BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0500

Length=295
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607641|ref|NP_215014.1|  pyrroline-5-carboxylate reductase [...   570    7e-161
gi|31791681|ref|NP_854174.1|  pyrroline-5-carboxylate reductase [...   569    2e-160
gi|308375174|ref|ZP_07442980.2|  pyrroline-5-carboxylate reductas...   561    5e-158
gi|294996008|ref|ZP_06801699.1|  pyrroline-5-carboxylate reductas...   478    4e-133
gi|240171904|ref|ZP_04750563.1|  pyrroline-5-carboxylate reductas...   439    2e-121
gi|15828312|ref|NP_302575.1|  pyrroline-5-carboxylate reductase [...   437    1e-120
gi|183980850|ref|YP_001849141.1|  pyrroline-5-carboxylate reducta...   433    2e-119
gi|118619662|ref|YP_907994.1|  pyrroline-5-carboxylate reductase ...   431    6e-119
gi|41410089|ref|NP_962925.1|  pyrroline-5-carboxylate reductase [...   417    1e-114
gi|336460454|gb|EGO39350.1|  pyrroline-5-carboxylate reductase [M...   416    2e-114
gi|118463455|ref|YP_883781.1|  pyrroline-5-carboxylate reductase ...   416    2e-114
gi|296168155|ref|ZP_06850176.1|  pyrroline-5-carboxylate reductas...   416    2e-114
gi|254777089|ref|ZP_05218605.1|  pyrroline-5-carboxylate reductas...   413    2e-113
gi|342858998|ref|ZP_08715652.1|  pyrroline-5-carboxylate reductas...   409    4e-112
gi|254821068|ref|ZP_05226069.1|  pyrroline-5-carboxylate reductas...   406    2e-111
gi|108797648|ref|YP_637845.1|  pyrroline-5-carboxylate reductase ...   401    5e-110
gi|118472220|ref|YP_885346.1|  pyrroline-5-carboxylate reductase ...   378    5e-103
gi|145220681|ref|YP_001131359.1|  pyrroline-5-carboxylate reducta...   372    3e-101
gi|120401852|ref|YP_951681.1|  pyrroline-5-carboxylate reductase ...   370    1e-100
gi|333989135|ref|YP_004521749.1|  pyrroline-5-carboxylate reducta...   347    1e-93 
gi|169631084|ref|YP_001704733.1|  pyrroline-5-carboxylate reducta...   336    3e-90 
gi|226361146|ref|YP_002778924.1|  pyrroline-5-carboxylate reducta...   284    1e-74 
gi|312141102|ref|YP_004008438.1|  pyrroline-5-carboxylate reducta...   283    2e-74 
gi|111019054|ref|YP_702026.1|  pyrroline-5-carboxylate reductase ...   281    8e-74 
gi|54027151|ref|YP_121393.1|  pyrroline-5-carboxylate reductase [...   265    8e-69 
gi|226305122|ref|YP_002765080.1|  pyrroline-5-carboxylate reducta...   258    7e-67 
gi|229490591|ref|ZP_04384429.1|  pyrroline-5-carboxylate reductas...   258    8e-67 
gi|326383055|ref|ZP_08204744.1|  pyrroline-5-carboxylate reductas...   230    2e-58 
gi|333918306|ref|YP_004491887.1|  pyrroline-5-carboxylate reducta...   230    2e-58 
gi|134103385|ref|YP_001109046.1|  pyrroline-5-carboxylate reducta...   229    4e-58 
gi|291004396|ref|ZP_06562369.1|  pyrroline-5-carboxylate reductas...   225    6e-57 
gi|117927456|ref|YP_872007.1|  pyrroline-5-carboxylate reductase ...   224    1e-56 
gi|262200999|ref|YP_003272207.1|  pyrroline-5-carboxylate reducta...   221    1e-55 
gi|237786469|ref|YP_002907174.1|  pyrroline-5-carboxylate reducta...   220    2e-55 
gi|258651142|ref|YP_003200298.1|  pyrroline-5-carboxylate reducta...   219    3e-55 
gi|257054352|ref|YP_003132184.1|  pyrroline-5-carboxylate reducta...   219    4e-55 
gi|343925953|ref|ZP_08765468.1|  pyrroline-5-carboxylate reductas...   217    2e-54 
gi|256380726|ref|YP_003104386.1|  pyrroline-5-carboxylate reducta...   216    3e-54 
gi|284034266|ref|YP_003384197.1|  pyrroline-5-carboxylate reducta...   215    6e-54 
gi|336326504|ref|YP_004606470.1|  Pyrroline-5-carboxylate reducta...   214    1e-53 
gi|311896780|dbj|BAJ29188.1|  putative pyrroline-5-carboxylate re...   213    3e-53 
gi|302523825|ref|ZP_07276167.1|  pyrroline-5-carboxylate reductas...   213    4e-53 
gi|225020266|ref|ZP_03709458.1|  hypothetical protein CORMATOL_00...   211    8e-53 
gi|305679732|ref|ZP_07402542.1|  pyrroline-5-carboxylate reductas...   211    1e-52 
gi|97180300|sp|P0C1E5.1|P5CR_CORML  RecName: Full=Pyrroline-5-car...   211    1e-52 
gi|72163107|ref|YP_290764.1|  pyrroline-5-carboxylate reductase [...   211    1e-52 
gi|19551656|ref|NP_599658.1|  pyrroline-5-carboxylate reductase [...   211    2e-52 
gi|62389310|ref|YP_224712.1|  pyrroline-5-carboxylate reductase [...   211    2e-52 
gi|297563917|ref|YP_003682890.1|  pyrroline-5-carboxylate reducta...   210    2e-52 
gi|317123802|ref|YP_004097914.1|  pyrroline-5-carboxylate reducta...   208    8e-52 


>gi|15607641|ref|NP_215014.1| pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis 
H37Rv]
 gi|15839892|ref|NP_334929.1| pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis 
CDC1551]
 gi|148660268|ref|YP_001281791.1| pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis 
H37Ra]
 50 more sequence titles
 Length=295

 Score =  570 bits (1470),  Expect = 7e-161, Method: Compositional matrix adjust.
 Identities = 295/295 (100%), Positives = 295/295 (100%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD
Sbjct  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT
Sbjct  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL
Sbjct  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE
Sbjct  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295


>gi|31791681|ref|NP_854174.1| pyrroline-5-carboxylate reductase [Mycobacterium bovis AF2122/97]
 gi|121636417|ref|YP_976640.1| pyrroline-5-carboxylate reductase [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224988889|ref|YP_002643576.1| pyrroline-5-carboxylate reductase [Mycobacterium bovis BCG str. 
Tokyo 172]
 20 more sequence titles
 Length=295

 Score =  569 bits (1466),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 294/295 (99%), Positives = 295/295 (100%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD
Sbjct  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT
Sbjct  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERM+QDQGGANGELMGL
Sbjct  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMDQDQGGANGELMGL  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE
Sbjct  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295


>gi|308375174|ref|ZP_07442980.2| pyrroline-5-carboxylate reductase proC [Mycobacterium tuberculosis 
SUMu007]
 gi|308376416|ref|ZP_07438768.2| pyrroline-5-carboxylate reductase proC [Mycobacterium tuberculosis 
SUMu008]
 gi|308347192|gb|EFP36043.1| pyrroline-5-carboxylate reductase proC [Mycobacterium tuberculosis 
SUMu007]
 gi|308351133|gb|EFP39984.1| pyrroline-5-carboxylate reductase proC [Mycobacterium tuberculosis 
SUMu008]
 gi|339293549|gb|AEJ45660.1| pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis 
CCDC5079]
Length=291

 Score =  561 bits (1445),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 291/291 (100%), Positives = 291/291 (100%), Gaps = 0/291 (0%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN
Sbjct  1    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR
Sbjct  61   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  120

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
            AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA
Sbjct  121  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  180

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL
Sbjct  181  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  240

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE
Sbjct  241  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  291


>gi|294996008|ref|ZP_06801699.1| pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis 
210]
Length=303

 Score =  478 bits (1231),  Expect = 4e-133, Method: Compositional matrix adjust.
 Identities = 247/247 (100%), Positives = 247/247 (100%), Gaps = 0/247 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD
Sbjct  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT
Sbjct  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL
Sbjct  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240

Query  241  RVDLTAS  247
            RVDLTAS
Sbjct  241  RVDLTAS  247


>gi|240171904|ref|ZP_04750563.1| pyrroline-5-carboxylate reductase [Mycobacterium kansasii ATCC 
12478]
Length=290

 Score =  439 bits (1130),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 244/291 (84%), Positives = 261/291 (90%), Gaps = 1/291 (0%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAER+P+RA YLA TYSVLVTS +DA+E+
Sbjct  1    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERIPERAKYLASTYSVLVTSVSDAIEH  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            ATFVVVAVKPADVE VI DLA A   A +DS EQVFVTV AG+T +YFESKLPAGTPV+R
Sbjct  61   ATFVVVAVKPADVETVIGDLAAAATGAGSDSVEQVFVTVAAGVTTSYFESKLPAGTPVIR  120

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
            AMPNAAALVGAGVTALAKGRFVTPQQL+EVSALFDAVG VL VPE QLDAVTAVSGSGPA
Sbjct  121  AMPNAAALVGAGVTALAKGRFVTPQQLKEVSALFDAVGVVLNVPEQQLDAVTAVSGSGPA  180

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFLLVEALVDAGV VGLSRQVAT+L AQT+AGS AMLLERMEQ++  A GE  GLRVD 
Sbjct  181  YFFLLVEALVDAGVAVGLSRQVATELTAQTLAGSTAMLLERMEQERPAA-GEPAGLRVDT  239

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            TA +LRA+VTSPGGTTAAALRELE+GGFR  VDAAV AAKSRSEQLRIT E
Sbjct  240  TALQLRASVTSPGGTTAAALRELEKGGFRGVVDAAVHAAKSRSEQLRITSE  290


>gi|15828312|ref|NP_302575.1| pyrroline-5-carboxylate reductase [Mycobacterium leprae TN]
 gi|221230789|ref|YP_002504205.1| pyrroline-5-carboxylate reductase [Mycobacterium leprae Br4923]
 gi|1172631|sp|P46725.1|P5CR_MYCLE RecName: Full=Pyrroline-5-carboxylate reductase; Short=P5C reductase; 
Short=P5CR
 gi|467049|gb|AAA17233.1| proC [Mycobacterium leprae]
 gi|13094005|emb|CAC31947.1| pyrroline-5-carboxylate reductase [Mycobacterium leprae]
 gi|219933896|emb|CAR72529.1| pyrroline-5-carboxylate reductase [Mycobacterium leprae Br4923]
Length=294

 Score =  437 bits (1123),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 243/295 (83%), Positives = 258/295 (88%), Gaps = 1/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML  MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRA YLA TYSVLVTS  D
Sbjct  1    MLSSMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRARYLADTYSVLVTSVTD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA FVVVAVKP DVE V+ DL  A A A NDSAEQV VTV AG+TI Y ESKLPAGT
Sbjct  61   AVENAMFVVVAVKPTDVESVMGDLVQAAAVA-NDSAEQVLVTVAAGVTITYLESKLPAGT  119

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVT LAKGRFVT QQ E+V A+FDAVGGVLTVPESQ+DAVTAVSG
Sbjct  120  PVVRAMPNAAALVGAGVTVLAKGRFVTGQQFEDVLAMFDAVGGVLTVPESQMDAVTAVSG  179

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGV VGL+RQVAT+LAAQTMAGSAAMLLERM+QD+  A    +G 
Sbjct  180  SGPAYFFLLVEALVDAGVAVGLTRQVATELAAQTMAGSAAMLLERMDQDRHSAEVAPLGA  239

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            +VD+ A++LRA +TSPGGTTAAALRELERGG RM VDAAVQAAK RSEQLRIT E
Sbjct  240  QVDVPAAQLRATITSPGGTTAAALRELERGGLRMVVDAAVQAAKIRSEQLRITSE  294


>gi|183980850|ref|YP_001849141.1| pyrroline-5-carboxylate reductase ProC [Mycobacterium marinum 
M]
 gi|183174176|gb|ACC39286.1| pyrroline-5-carboxylate reductase ProC [Mycobacterium marinum 
M]
Length=294

 Score =  433 bits (1113),  Expect = 2e-119, Method: Compositional matrix adjust.
 Identities = 241/295 (82%), Positives = 262/295 (89%), Gaps = 1/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GM RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAER+P+RA YLA TYSVLVTSA D
Sbjct  1    MLSGMPRIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERVPERAKYLASTYSVLVTSAKD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            A E+A+ VVVAVKP DV+ V+ DL+   AAAE+ S EQVFVTV AG+T +YFESKLPAGT
Sbjct  61   AAESASLVVVAVKPGDVDSVMGDLSAVVAAAESYSGEQVFVTVAAGVTTSYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALV AGVTALAKGRFVTP+QLEEVSALFD+VG VLTVPE QLDAVTA+SG
Sbjct  121  PVVRAMPNAAALVSAGVTALAKGRFVTPEQLEEVSALFDSVGVVLTVPEQQLDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYF L+VEALVDAGV  GLSRQVATDL AQTMAGSAAMLLERM+QD+ GA  E +GL
Sbjct  181  SGPAYFLLMVEALVDAGVAAGLSRQVATDLTAQTMAGSAAMLLERMDQDRRGA-AEPLGL  239

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD + ++LRA+VTSPGGTTAAALRELER GFR AVDAAVQAAKSRSEQLRIT E
Sbjct  240  RVDTSPAQLRASVTSPGGTTAAALRELEREGFRGAVDAAVQAAKSRSEQLRITSE  294


>gi|118619662|ref|YP_907994.1| pyrroline-5-carboxylate reductase [Mycobacterium ulcerans Agy99]
 gi|118571772|gb|ABL06523.1| pyrroline-5-carboxylate reductase ProC [Mycobacterium ulcerans 
Agy99]
Length=294

 Score =  431 bits (1109),  Expect = 6e-119, Method: Compositional matrix adjust.
 Identities = 240/295 (82%), Positives = 262/295 (89%), Gaps = 1/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GM RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAER+P+RA YLA TYSVLVTSA D
Sbjct  1    MLSGMPRIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERVPERAKYLASTYSVLVTSAKD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            A E+A+ VVVAVKP DV+ V+ DL+   AAAE+ S EQVFVTV AG+T +YFESKLPAGT
Sbjct  61   AAESASLVVVAVKPGDVDSVMGDLSAVVAAAESYSGEQVFVTVAAGVTTSYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALV AGVTALAKGRFVTP+QLEEVSALFD+VG VLTVPE QLDAVTA+SG
Sbjct  121  PVVRAMPNAAALVSAGVTALAKGRFVTPEQLEEVSALFDSVGVVLTVPEQQLDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYF L+VEALVDAGV  GLSRQVATDL AQTMAGSAAMLLERM+QD+ GA  E +GL
Sbjct  181  SGPAYFLLMVEALVDAGVAAGLSRQVATDLTAQTMAGSAAMLLERMDQDRRGA-AEPLGL  239

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            R+D + ++LRA+VTSPGGTTAAALRELER GFR AVDAAVQAAKSRSEQLRIT E
Sbjct  240  RLDTSPAQLRASVTSPGGTTAAALRELEREGFRGAVDAAVQAAKSRSEQLRITSE  294


>gi|41410089|ref|NP_962925.1| pyrroline-5-carboxylate reductase [Mycobacterium avium subsp. 
paratuberculosis K-10]
 gi|41398922|gb|AAS06541.1| ProC [Mycobacterium avium subsp. paratuberculosis K-10]
Length=298

 Score =  417 bits (1071),  Expect = 1e-114, Method: Compositional matrix adjust.
 Identities = 239/295 (82%), Positives = 260/295 (89%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL+TS AD
Sbjct  4    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLITSVAD  63

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V++++A A   AE+D+AEQVFVTV AG+TI YFES+LPAGT
Sbjct  64   AVENASFVVVAVKPADVESVMSEIARAAGQAESDTAEQVFVTVAAGVTIGYFESRLPAGT  123

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAA LVGAGVTALAKGRFVT  QLE VSALFD+VGGVL+VPESQ+DAVTA+SG
Sbjct  124  PVVRAMPNAAVLVGAGVTALAKGRFVTAPQLEGVSALFDSVGGVLSVPESQMDAVTALSG  183

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGV  GLSR+VA DL AQTMAGSAAMLLERM+ D+     E  GL
Sbjct  184  SGPAYFFLLVEALVDAGVAAGLSREVAADLTAQTMAGSAAMLLERMDADRRLGEAETPGL  243

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VTSPGGTTAA LRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  244  RVDATATQLRATVTSPGGTTAAGLRELERGGLRAAVDAAVQAAKMRSEQLRITSE  298


>gi|336460454|gb|EGO39350.1| pyrroline-5-carboxylate reductase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=295

 Score =  416 bits (1070),  Expect = 2e-114, Method: Compositional matrix adjust.
 Identities = 239/295 (82%), Positives = 260/295 (89%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL+TS AD
Sbjct  1    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLITSVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V++++A A   AE+D+AEQVFVTV AG+TI YFES+LPAGT
Sbjct  61   AVENASFVVVAVKPADVESVMSEIARAAGQAESDTAEQVFVTVAAGVTIGYFESRLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAA LVGAGVTALAKGRFVT  QLE VSALFD+VGGVL+VPESQ+DAVTA+SG
Sbjct  121  PVVRAMPNAAVLVGAGVTALAKGRFVTAPQLEGVSALFDSVGGVLSVPESQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGV  GLSR+VA DL AQTMAGSAAMLLERM+ D+     E  GL
Sbjct  181  SGPAYFFLLVEALVDAGVAAGLSREVAADLTAQTMAGSAAMLLERMDADRRLGEAETPGL  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VTSPGGTTAA LRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  241  RVDATATQLRATVTSPGGTTAAGLRELERGGLRAAVDAAVQAAKMRSEQLRITSE  295


>gi|118463455|ref|YP_883781.1| pyrroline-5-carboxylate reductase [Mycobacterium avium 104]
 gi|118164742|gb|ABK65639.1| pyrroline-5-carboxylate reductase [Mycobacterium avium 104]
Length=295

 Score =  416 bits (1069),  Expect = 2e-114, Method: Compositional matrix adjust.
 Identities = 239/295 (82%), Positives = 261/295 (89%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL+TS AD
Sbjct  1    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLMTSVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V++++A A   AE+D+AEQVFVTV AG+TI YFES+LPAGT
Sbjct  61   AVENASFVVVAVKPADVESVMSEIARAAGQAESDTAEQVFVTVAAGVTIGYFESRLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVT  QLE VSALFD+VGGVL+VPESQ+DAVTA+SG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTAPQLEGVSALFDSVGGVLSVPESQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGV  GLSR+VA DL AQTMAGSAAMLLERM+ D+     E  G+
Sbjct  181  SGPAYFFLLVEALVDAGVAAGLSREVAADLTAQTMAGSAAMLLERMDADRRLGEAETPGM  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VTSPGGTTAA LRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  241  RVDATATQLRATVTSPGGTTAAGLRELERGGLRAAVDAAVQAAKIRSEQLRITSE  295


>gi|296168155|ref|ZP_06850176.1| pyrroline-5-carboxylate reductase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295896833|gb|EFG76462.1| pyrroline-5-carboxylate reductase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=295

 Score =  416 bits (1069),  Expect = 2e-114, Method: Compositional matrix adjust.
 Identities = 238/295 (81%), Positives = 263/295 (90%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAER+P+RA YLA TYSVL+TS AD
Sbjct  1    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERIPERAQYLADTYSVLITSVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKP DVEPV+A+L   +AA+E+DSAEQVFVTV AGI I+YFESKLPAGT
Sbjct  61   AVENASFVVVAVKPGDVEPVMAELTRVSAASESDSAEQVFVTVAAGIGISYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALA GRFV+ +QL+ VSALFD+VGGVLTVPE+Q+DAVTA+SG
Sbjct  121  PVVRAMPNAAALVGAGVTALATGRFVSSEQLQGVSALFDSVGGVLTVPEAQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFL+VEALVDAGV  GLSR+VATDL AQTMAGSAAMLLERM+ ++    GE    
Sbjct  181  SGPAYFFLMVEALVDAGVAAGLSREVATDLTAQTMAGSAAMLLERMDAERRPVEGEGPAP  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD  A++LRA VTSPGGTTAA LRELERGG R AVDAAVQAAK+RSEQLRIT E
Sbjct  241  RVDAAATQLRATVTSPGGTTAAGLRELERGGLRAAVDAAVQAAKTRSEQLRITSE  295


>gi|254777089|ref|ZP_05218605.1| pyrroline-5-carboxylate reductase [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=295

 Score =  413 bits (1062),  Expect = 2e-113, Method: Compositional matrix adjust.
 Identities = 238/295 (81%), Positives = 260/295 (89%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL+TS AD
Sbjct  1    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLMTSVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V++++A A   AE+D+AEQVFVTV AG+TI YFES+LPAGT
Sbjct  61   AVENASFVVVAVKPADVESVMSEIARAAGQAESDTAEQVFVTVAAGVTIGYFESRLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVT  QLE VSALFD+VGGVL+VPESQ+DAVTA+SG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTAPQLEGVSALFDSVGGVLSVPESQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEALVDAGV  GLSR+VA DL AQTMAGSAAMLLERM+ D+     E  G+
Sbjct  181  SGPAYFFLLVEALVDAGVAAGLSREVAADLTAQTMAGSAAMLLERMDADRRLGEAETPGM  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VT PGGTTAA LRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  241  RVDATATQLRATVTFPGGTTAAGLRELERGGLRAAVDAAVQAAKIRSEQLRITSE  295


>gi|342858998|ref|ZP_08715652.1| pyrroline-5-carboxylate reductase [Mycobacterium colombiense 
CECT 3035]
 gi|342133239|gb|EGT86442.1| pyrroline-5-carboxylate reductase [Mycobacterium colombiense 
CECT 3035]
Length=295

 Score =  409 bits (1050),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 240/295 (82%), Positives = 261/295 (89%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL++S +D
Sbjct  1    MLCGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLISSVSD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V+A++A A  AAE+D+AEQVFVTV AGITI YFESKLPAGT
Sbjct  61   AVENASFVVVAVKPADVESVMAEIARAAGAAESDTAEQVFVTVAAGITITYFESKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPNAAALVGAGVTALAKGRFVT  QLE VSALFD+VGGVL+VPE Q+DAVTA+SG
Sbjct  121  PVVRAMPNAAALVGAGVTALAKGRFVTAPQLEGVSALFDSVGGVLSVPEGQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFLLVEAL+DAGV  GLSR+VA DL AQTMAGSAAMLLERM+ D+     E  GL
Sbjct  181  SGPAYFFLLVEALIDAGVAAGLSREVAADLTAQTMAGSAAMLLERMDADRQLGEAEAPGL  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VTSPGGTTAA LRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  241  RVDATATQLRATVTSPGGTTAAGLRELERGGLRAAVDAAVQAAKMRSEQLRITSE  295


>gi|254821068|ref|ZP_05226069.1| pyrroline-5-carboxylate reductase [Mycobacterium intracellulare 
ATCC 13950]
Length=295

 Score =  406 bits (1044),  Expect = 2e-111, Method: Compositional matrix adjust.
 Identities = 237/295 (81%), Positives = 264/295 (90%), Gaps = 0/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALLSGLLRAGRQVKDLVV ER+P+RA YLA TYSVL+TS A+
Sbjct  1    MLSGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVVERVPERAKYLADTYSVLITSVAE  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AVENA+FVVVAVKPADVE V++++A A A AE+D+AEQVFVTV AG+TIAYFE+KLPAGT
Sbjct  61   AVENASFVVVAVKPADVESVMSEVARAAAEAESDTAEQVFVTVAAGVTIAYFEAKLPAGT  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVRAMPN AALVGAGVTALAKGRFVTP QLE VSALFD+VGGVL+VPE Q+DAVTA+SG
Sbjct  121  PVVRAMPNTAALVGAGVTALAKGRFVTPPQLEGVSALFDSVGGVLSVPEGQMDAVTALSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFL+VEAL+DAGV  GLSR+VA DL AQTMAG+AAMLLERM+ D+  +  E  G+
Sbjct  181  SGPAYFFLMVEALIDAGVAAGLSREVAGDLTAQTMAGAAAMLLERMDADRRLSEAEAPGM  240

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            RVD TA++LRA VTSPGGTTAAALRELERGG R AVDAAVQAAK RSEQLRIT E
Sbjct  241  RVDATATQLRATVTSPGGTTAAALRELERGGLRAAVDAAVQAAKMRSEQLRITSE  295


>gi|108797648|ref|YP_637845.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. MCS]
 gi|119866735|ref|YP_936687.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. KMS]
 gi|126433272|ref|YP_001068963.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. JLS]
 gi|108768067|gb|ABG06789.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. MCS]
 gi|119692824|gb|ABL89897.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. KMS]
 gi|126233072|gb|ABN96472.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. JLS]
Length=294

 Score =  401 bits (1031),  Expect = 5e-110, Method: Compositional matrix adjust.
 Identities = 213/295 (73%), Positives = 248/295 (85%), Gaps = 1/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML+ MARIAIIGGGS+GEALLSGLLRAGRQVKDLVVAE+ PDRA +LA+ +SVLVTS  +
Sbjct  1    MLWRMARIAIIGGGSMGEALLSGLLRAGRQVKDLVVAEKHPDRAKFLAEKHSVLVTSVVE  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            A++NA +V+VAVKPADVE VI D+A A A A+ D+AEQVFVTV AG++ AY+E+KLPAG 
Sbjct  61   AIDNAHYVIVAVKPADVEHVIDDIAEAAANADTDTAEQVFVTVAAGVSTAYYENKLPAGA  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PV+RAMPNA  +VG GV+ALA GRF TP+ L+EVSA+FD+VGGVLTVPESQLDAVTAVSG
Sbjct  121  PVIRAMPNAPVVVGGGVSALAPGRFATPEHLKEVSAIFDSVGGVLTVPESQLDAVTAVSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFL+VEALVDA V  GLSR VATDL  QTMAGSAAMLLER+++ Q   +   MG 
Sbjct  181  SGPAYFFLMVEALVDAAVASGLSRTVATDLVVQTMAGSAAMLLERLDEAQPVGDAA-MGT  239

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
             +D TA++LRA VTSP GTTAA LRELERGG R AV  AV+AAK+RSEQL IT E
Sbjct  240  AMDTTAAQLRATVTSPAGTTAAGLRELERGGLRSAVANAVEAAKTRSEQLGITSE  294


>gi|118472220|ref|YP_885346.1| pyrroline-5-carboxylate reductase [Mycobacterium smegmatis str. 
MC2 155]
 gi|118173507|gb|ABK74403.1| pyrroline-5-carboxylate reductase [Mycobacterium smegmatis str. 
MC2 155]
Length=286

 Score =  378 bits (971),  Expect = 5e-103, Method: Compositional matrix adjust.
 Identities = 211/291 (73%), Positives = 241/291 (83%), Gaps = 5/291 (1%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M+RIAIIGGGS+GEALLSGLLRAGRQVKD+VVAE+ P+RA YLA  YSV VTS ADA EN
Sbjct  1    MSRIAIIGGGSMGEALLSGLLRAGRQVKDMVVAEKFPERAKYLADKYSVRVTSVADAAEN  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A +VVVAVKPADVE VI ++A A A AE D+AEQVFVT+ AG+  AY+E+KLPAG+PV+R
Sbjct  61   AHYVVVAVKPADVEKVIGEIAEAAANAETDTAEQVFVTIAAGVGTAYYEAKLPAGSPVIR  120

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPNA  +VG GV+ALA GRF TP+QL+EVS LFDAVGGV+TV ESQLDAVTA+SGSGPA
Sbjct  121  VMPNAPVIVGGGVSALAPGRFATPEQLKEVSTLFDAVGGVITVSESQLDAVTALSGSGPA  180

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFL+ EA+VDAGV VGLSR VATDL AQTMAGSAAMLL+R+  DQ  A G   G  +D 
Sbjct  181  YFFLMAEAMVDAGVAVGLSRAVATDLVAQTMAGSAAMLLDRL--DQVNAAG---GAALDT  235

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            T ++LRA VTSP GTTAA LRELERGG R AV  AV+AAK+RSEQL IT E
Sbjct  236  TPAQLRATVTSPAGTTAAGLRELERGGLRAAVANAVEAAKTRSEQLGITSE  286


>gi|145220681|ref|YP_001131359.1| pyrroline-5-carboxylate reductase [Mycobacterium gilvum PYR-GCK]
 gi|315442367|ref|YP_004075246.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. Spyr1]
 gi|145213167|gb|ABP42571.1| pyrroline-5-carboxylate reductase [Mycobacterium gilvum PYR-GCK]
 gi|315260670|gb|ADT97411.1| pyrroline-5-carboxylate reductase [Mycobacterium sp. Spyr1]
Length=293

 Score =  372 bits (956),  Expect = 3e-101, Method: Compositional matrix adjust.
 Identities = 212/295 (72%), Positives = 248/295 (85%), Gaps = 2/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML  MARIAIIGGGSIGEALL+GLLRAGRQVKDLVVAE+ PDR  YLA+ YSVLVT+ AD
Sbjct  1    MLARMARIAIIGGGSIGEALLAGLLRAGRQVKDLVVAEKSPDRGKYLAEKYSVLVTTVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AV+ AT+V+VAVKPADV+ VI D+A+  A A++D+AEQVFV+V AG++ +++ESKLPAG+
Sbjct  61   AVDAATYVIVAVKPADVQHVIGDIADTAARADSDAAEQVFVSVAAGVSTSFYESKLPAGS  120

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PV+R MPNA  LVG GV+ALA GRF +P+QL+EVS LFDAVGGVLTV ESQ+DAVTAVSG
Sbjct  121  PVIRVMPNAPMLVGGGVSALAPGRFASPEQLKEVSLLFDAVGGVLTVAESQIDAVTAVSG  180

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFL+VEALVDAGV  GL R VATDLA QTMAGSAAMLLER++Q+  G+     G 
Sbjct  181  SGPAYFFLMVEALVDAGVDAGLPRAVATDLAVQTMAGSAAMLLERLDQNAAGSASA--GP  238

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
             +D +A++LRA VTSPGGTTAA LRELERGG R AV  AV+AAK RSEQL IT E
Sbjct  239  SMDTSAAQLRATVTSPGGTTAAGLRELERGGLRAAVANAVEAAKKRSEQLGITTE  293


>gi|120401852|ref|YP_951681.1| pyrroline-5-carboxylate reductase [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954670|gb|ABM11675.1| pyrroline-5-carboxylate reductase [Mycobacterium vanbaalenii 
PYR-1]
Length=306

 Score =  370 bits (951),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 212/295 (72%), Positives = 247/295 (84%), Gaps = 1/295 (0%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML GMARIAIIGGGSIGEALL+GLLRAGRQVKDLVVAE+ P RA YLA+ YSVLVT+ +D
Sbjct  13   MLCGMARIAIIGGGSIGEALLAGLLRAGRQVKDLVVAEKNPGRAKYLAEKYSVLVTAVSD  72

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGT  120
            AV+ AT+VVVAVKP+DV+ VI D+A+  A AE+++AEQVFVTV AG++ AY+E+KLPAG+
Sbjct  73   AVDAATYVVVAVKPSDVQYVIGDIADTAARAESNAAEQVFVTVAAGVSTAYYENKLPAGS  132

Query  121  PVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSG  180
            PVVR MPNA  LVG GV+ALA GRF T + L+EVS LFDAVGGVLTV ESQ+DAVTAVSG
Sbjct  133  PVVRVMPNAPMLVGGGVSALAPGRFATQEHLKEVSLLFDAVGGVLTVAESQIDAVTAVSG  192

Query  181  SGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGL  240
            SGPAYFFL+VEALVDA V  GL+R VATDL  QTMAGSAAMLLER+++    +N    G 
Sbjct  193  SGPAYFFLMVEALVDAAVDAGLARSVATDLVVQTMAGSAAMLLERLDE-SAPSNDSAAGA  251

Query  241  RVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
             +D +A++LRA VTSPGGTTAA LRELERGG R AV  AV+AAK+RSEQL ITPE
Sbjct  252  FMDTSAAQLRATVTSPGGTTAAGLRELERGGLRAAVANAVEAAKTRSEQLGITPE  306


>gi|333989135|ref|YP_004521749.1| pyrroline-5-carboxylate reductase ProC [Mycobacterium sp. JDM601]
 gi|333485103|gb|AEF34495.1| pyrroline-5-carboxylate reductase ProC [Mycobacterium sp. JDM601]
Length=286

 Score =  347 bits (890),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 198/292 (68%), Positives = 230/292 (79%), Gaps = 7/292 (2%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M RIAIIGGG++GEALL+GLL AGR VKDLVVAER  DRA  L++ YSVLVTS ADAVEN
Sbjct  1    MTRIAIIGGGNMGEALLAGLLAAGRPVKDLVVAERFGDRARQLSEKYSVLVTSVADAVEN  60

Query  65   ATFVVVAVKPADVEPVIADLA-NATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
            A+ V+VAVKP DVE V+A+ A N TAA+EN S EQV V++VAG+T  Y ESKLPAGT V+
Sbjct  61   ASIVIVAVKPQDVESVVAEFAKNLTAASEN-SPEQVLVSIVAGVTTGYVESKLPAGTAVI  119

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN    VGAG +ALAKGRF + +Q+E+V+ LF+ VG V+ VPE Q+D+VTAVSGSGP
Sbjct  120  RVMPNTPVKVGAGASALAKGRFASSEQVEQVAELFECVGTVVIVPEEQMDSVTAVSGSGP  179

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AYFFL+VEALVDAGV  GLSRQ ATDLA QTMAGSA MLLE   +  G AN       +D
Sbjct  180  AYFFLMVEALVDAGVAAGLSRQGATDLAVQTMAGSAQMLLEERGETAGTANS-----VID  234

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
               ++LRA VTSPGGTTAAALRELE GG R +VD AV+AAK+RSEQLRIT E
Sbjct  235  TGPAQLRAMVTSPGGTTAAALRELEAGGLRTSVDRAVRAAKTRSEQLRITSE  286


>gi|169631084|ref|YP_001704733.1| pyrroline-5-carboxylate reductase [Mycobacterium abscessus ATCC 
19977]
 gi|169243051|emb|CAM64079.1| Probable pyrroline-5-carboxylate reductase ProC [Mycobacterium 
abscessus]
Length=299

 Score =  336 bits (862),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 193/299 (65%), Positives = 228/299 (77%), Gaps = 4/299 (1%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAAD  60
            ML  M+RIAIIGGG+IGEAL+SGLLRAGRQ KD+VV+E++P RA  LA  YS+ ++  AD
Sbjct  1    MLVAMSRIAIIGGGNIGEALISGLLRAGRQAKDIVVSEKVPARARALADAYSIRISEVAD  60

Query  61   AVENATFVVVAVKPADVEPVIADLANATAAAENDSAE----QVFVTVVAGITIAYFESKL  116
            AVE A F+VVAVKP+DVE    ++A A A  + + +E    QV V+V AG++  +FESKL
Sbjct  61   AVEGADFIVVAVKPSDVESATTEIAAALAKLDAEGSERETEQVLVSVAAGVSTGFFESKL  120

Query  117  PAGTPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVT  176
             AG PVVR MPNA  LVGAGV+ALAKGRF   +QL  V+ L ++VG V+TV ESQ+D VT
Sbjct  121  AAGAPVVRVMPNAPMLVGAGVSALAKGRFANDEQLSAVAELLESVGTVITVAESQMDTVT  180

Query  177  AVSGSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGE  236
            A+SGSGPAYFFLLVEALVDAGV  GL+R VATDL  QTMAGSAAMLLER E D+  A G 
Sbjct  181  AISGSGPAYFFLLVEALVDAGVASGLTRPVATDLVIQTMAGSAAMLLERAESDENRAPGL  240

Query  237  LMGLRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
                 VD TA+ LRA +TSPGGTTAAALRELERGG R +V AAV AAK+RSEQL IT E
Sbjct  241  QTRTEVDTTAAELRATITSPGGTTAAALRELERGGLRASVYAAVDAAKTRSEQLGITSE  299


>gi|226361146|ref|YP_002778924.1| pyrroline-5-carboxylate reductase [Rhodococcus opacus B4]
 gi|226239631|dbj|BAH49979.1| pyrroline-5-carboxylate reductase [Rhodococcus opacus B4]
Length=271

 Score =  284 bits (727),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 161/291 (56%), Positives = 199/291 (69%), Gaps = 20/291 (6%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M RIA+IGGG IGEAL+SGLL+AG  VKDLVVAE+ P RA+ LA  YSV VT+  DA E 
Sbjct  1    MTRIAVIGGGKIGEALISGLLQAGHAVKDLVVAEQHPVRADELAAAYSVRVTTPTDAAEG  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +V+AVKP DVE  + +++      E    EQ+ V++ AGI  A++E++LPAG PVVR
Sbjct  61   ADVIVMAVKPGDVESALTEVSKVELDGER---EQLLVSLAAGIPTAFYETRLPAGFPVVR  117

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG GV+ LA GR V  + LE V  +  +VG V+ VPESQ+DAVTAVSGSGPA
Sbjct  118  VMPNTPMLVGEGVSVLAPGRHVKKEHLELVRGVLSSVGKVVVVPESQIDAVTAVSGSGPA  177

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFL+ EA++DAGVG+GL+R  AT+L  QTM GSAAML      D+ G +          
Sbjct  178  YFFLVAEAMIDAGVGLGLTRATATELVVQTMVGSAAML------DRSGES----------  221

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
             A+ LRAAVTSPGGTTAAA+R LE  G R A   A++AAK RS +L  T E
Sbjct  222  -ATELRAAVTSPGGTTAAAIRRLEGNGLRTAFFDALEAAKIRSAELGTTTE  271


>gi|312141102|ref|YP_004008438.1| pyrroline-5-carboxylate reductase proc [Rhodococcus equi 103S]
 gi|325674088|ref|ZP_08153778.1| pyrroline-5-carboxylate reductase [Rhodococcus equi ATCC 33707]
 gi|311890441|emb|CBH49759.1| pyrroline-5-carboxylate reductase ProC [Rhodococcus equi 103S]
 gi|325555353|gb|EGD25025.1| pyrroline-5-carboxylate reductase [Rhodococcus equi ATCC 33707]
Length=271

 Score =  283 bits (724),  Expect = 2e-74, Method: Compositional matrix adjust.
 Identities = 161/291 (56%), Positives = 197/291 (68%), Gaps = 20/291 (6%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M RIA+IGGG IGEAL+SGLL+ G   +DLVVAE+   RA  LA  YS+ VT+  DA E 
Sbjct  1    MTRIAVIGGGKIGEALVSGLLQGGHATRDLVVAEQYEPRAEELAAAYSIRVTTPEDAAEG  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +VVAVKP DV+ V+A L+      E    EQ+ V++ AGI+ A +ESKLPAG PVVR
Sbjct  61   ADVIVVAVKPTDVDSVLAALSKVDLDGER---EQIIVSLAAGISTARYESKLPAGFPVVR  117

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG G +A+A GR V P+ L+ V  +   VG V TVPESQ+DAVTAVSGSGPA
Sbjct  118  VMPNTPMLVGQGASAIAPGRHVKPEHLDLVRGILATVGAVTTVPESQIDAVTAVSGSGPA  177

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFL  EA++DAGV +GL+R  A++L  QTM GSAAML E         +GE        
Sbjct  178  YFFLAAEAMIDAGVSLGLTRATASELVVQTMIGSAAMLAE---------SGE--------  220

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
            +A+ LRAAVTSPGGTTAAA+RELER G R A   A+ AA+ RS +L + PE
Sbjct  221  SANDLRAAVTSPGGTTAAAVRELERCGLRTAFYEALAAARDRSAELGVAPE  271


>gi|111019054|ref|YP_702026.1| pyrroline-5-carboxylate reductase [Rhodococcus jostii RHA1]
 gi|110818584|gb|ABG93868.1| pyrroline-5-carboxylate reductase [Rhodococcus jostii RHA1]
Length=271

 Score =  281 bits (719),  Expect = 8e-74, Method: Compositional matrix adjust.
 Identities = 158/291 (55%), Positives = 200/291 (69%), Gaps = 20/291 (6%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M RIA+IGGG IGEAL+SGLL+AG  VKDLVVAE+ P RA+ LA  Y+V VT+ +DA E 
Sbjct  1    MTRIAVIGGGKIGEALISGLLQAGHAVKDLVVAEQHPARADELAAAYAVRVTTPSDAAEG  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +V+AVKP DVE  + +++      E    EQ+ V++ AGI  A++E++LPAG PVVR
Sbjct  61   ADVIVIAVKPGDVEAALTEVSKVELDGER---EQLLVSLAAGIPTAFYETRLPAGFPVVR  117

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG GV+ LA GR V  + LE V  +  +VG V+ VPESQ+DAVTAVSGSGPA
Sbjct  118  VMPNTPMLVGEGVSVLAPGRHVKKEHLELVRGVLSSVGKVVVVPESQIDAVTAVSGSGPA  177

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFL+ EA++DAGVG+GL+R  A++L  QTM GSAAML      D+ G +          
Sbjct  178  YFFLVAEAMIDAGVGLGLTRATASELVVQTMVGSAAML------DRSGES----------  221

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE  295
             A+ LRAAVTSPGGTTAAA+R LE  G R A   A++AAK RS +L  + E
Sbjct  222  -ATELRAAVTSPGGTTAAAIRRLEGNGLRTAFFDALEAAKIRSAELGTSTE  271


>gi|54027151|ref|YP_121393.1| pyrroline-5-carboxylate reductase [Nocardia farcinica IFM 10152]
 gi|54018659|dbj|BAD60029.1| putative pyrroline-5-carboxylate reductase [Nocardia farcinica 
IFM 10152]
Length=273

 Score =  265 bits (676),  Expect = 8e-69, Method: Compositional matrix adjust.
 Identities = 156/286 (55%), Positives = 189/286 (67%), Gaps = 20/286 (6%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTS-AADAVE  63
            M RIA+IGGG IGEAL++GLL +GR  KDLVV E   DRA  +A  + V VT+  ADA  
Sbjct  1    MTRIAVIGGGRIGEALIAGLLESGRASKDLVVVETHQDRAELVASRFGVRVTAEVADAAI  60

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
             A  +V+AVKP DV+ V+  L  A   A +   +QV V++ AG+  A  E+K+PAG PVV
Sbjct  61   GADLLVIAVKPGDVDTVLTQLGKAELNAGD--VDQVLVSLAAGVPTARLEAKMPAGFPVV  118

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG G+  LA GR+  P QLE V+ +   VG V+TV ESQ+DAVTAVSGSGP
Sbjct  119  RVMPNTPMLVGQGMIVLAPGRYTKPSQLELVTEVLGTVGKVVTVAESQMDAVTAVSGSGP  178

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AYFFL+VEA++DA V +GLSR +ATDL  QTM GSAA LL+  EQ               
Sbjct  179  AYFFLVVEAMIDAAVSLGLSRDIATDLVVQTMVGSAA-LLDEAEQ---------------  222

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQ  289
             +A  LRAAVTSP GTTAAALRELER G R A   A+ AAK RS +
Sbjct  223  -SAVELRAAVTSPAGTTAAALRELERAGVRSAFLEALHAAKERSAE  267


>gi|226305122|ref|YP_002765080.1| pyrroline-5-carboxylate reductase [Rhodococcus erythropolis PR4]
 gi|226184237|dbj|BAH32341.1| pyrroline-5-carboxylate reductase [Rhodococcus erythropolis PR4]
Length=271

 Score =  258 bits (660),  Expect = 7e-67, Method: Compositional matrix adjust.
 Identities = 148/270 (55%), Positives = 185/270 (69%), Gaps = 20/270 (7%)

Query  18   EALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADV  77
            EAL+SGLL+AG  +KDLVVAE+   RA+ L   YS+ V++ ADA E A  +V+AVKP DV
Sbjct  14   EALISGLLQAGHAIKDLVVAEQYQPRADELIAEYSIRVSTIADAAEGADVIVIAVKPGDV  73

Query  78   EPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGV  137
            E  +  L   T    +   EQ+ V++ AGI   +FE++LPAG PV+R MPN   LVG GV
Sbjct  74   ESALTAL---TKVDLDGDLEQLIVSLAAGIPTGFFETRLPAGFPVIRVMPNTPMLVGEGV  130

Query  138  TALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAG  197
            + L+ GR V  + LE V  +  +VG V+TVPESQ+DAVTAVSGSGPAYFFL+ EA++DAG
Sbjct  131  SVLSPGRHVKAEHLELVRGILGSVGKVVTVPESQIDAVTAVSGSGPAYFFLVAEAMIDAG  190

Query  198  VGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPG  257
            VG+GL+R VAT+L  QTM GSAAML      D+ G +           A+ LRAAVTSPG
Sbjct  191  VGLGLTRPVATELVVQTMVGSAAML------DRTGDS-----------ATDLRAAVTSPG  233

Query  258  GTTAAALRELERGGFRMAVDAAVQAAKSRS  287
            GTTAAALR+LE GG R A   A+ AAKSRS
Sbjct  234  GTTAAALRQLEAGGLRTAFFDALDAAKSRS  263


>gi|229490591|ref|ZP_04384429.1| pyrroline-5-carboxylate reductase [Rhodococcus erythropolis SK121]
 gi|229322411|gb|EEN88194.1| pyrroline-5-carboxylate reductase [Rhodococcus erythropolis SK121]
Length=271

 Score =  258 bits (659),  Expect = 8e-67, Method: Compositional matrix adjust.
 Identities = 148/270 (55%), Positives = 185/270 (69%), Gaps = 20/270 (7%)

Query  18   EALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADV  77
            EAL+SGLL+AG  +KDLVVAE+   RA+ L   YS+ V++ ADA E A  +V+AVKP DV
Sbjct  14   EALISGLLQAGHAIKDLVVAEQYQPRADELIAEYSIRVSTVADAAEGADVIVIAVKPNDV  73

Query  78   EPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGV  137
            E  +  L   T    +   EQ+ V++ AGI   +FE++LPAG PV+R MPN   LVG GV
Sbjct  74   ESALTAL---TKVDLDGDLEQLIVSLAAGIPTGFFETRLPAGFPVIRVMPNTPMLVGEGV  130

Query  138  TALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAG  197
            + L+ GR V  + LE V  +  +VG V+TVPESQ+DAVTAVSGSGPAYFFL+ EA++DAG
Sbjct  131  SVLSPGRHVKAEHLELVRGILGSVGKVVTVPESQIDAVTAVSGSGPAYFFLVAEAMIDAG  190

Query  198  VGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPG  257
            VG+GL+R VAT+L  QTM GSAAML      D+ G +           A+ LRAAVTSPG
Sbjct  191  VGLGLTRPVATELVVQTMVGSAAML------DRTGDS-----------ATDLRAAVTSPG  233

Query  258  GTTAAALRELERGGFRMAVDAAVQAAKSRS  287
            GTTAAALR+LE GG R A   A+ AAKSRS
Sbjct  234  GTTAAALRQLEAGGLRTAFFDALDAAKSRS  263


>gi|326383055|ref|ZP_08204744.1| pyrroline-5-carboxylate reductase [Gordonia neofelifaecis NRRL 
B-59395]
 gi|326198191|gb|EGD55376.1| pyrroline-5-carboxylate reductase [Gordonia neofelifaecis NRRL 
B-59395]
Length=292

 Score =  230 bits (586),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 133/274 (49%), Positives = 177/274 (65%), Gaps = 21/274 (7%)

Query  7    RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTS-AADAVENA  65
            R+AIIGGG IGEALL+GL+ AG+ VKDLVV ER P+R+  L   Y V V+    DAVE A
Sbjct  4    RVAIIGGGKIGEALLAGLISAGKPVKDLVVIERSPERSAELVDDYGVRVSDDITDAVEGA  63

Query  66   TFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRA  125
              V +AVKP  V+ V+  L   +   ++   E+V V++VAGI  + +E+ L AG+PV+R 
Sbjct  64   RVVFIAVKPDAVDTVLQKL---SVTDDDGELERVTVSLVAGIPTSRYEAALQAGSPVIRV  120

Query  126  MPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAY  185
            MPN   LV   ++A++ GR+    Q+     L ++VG V+ VPE Q+DAVTA+SGSGPAY
Sbjct  121  MPNTPMLVNEAMSAVSPGRYAEDDQVALTVRLLESVGKVMVVPEKQMDAVTAISGSGPAY  180

Query  186  FFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLT  245
            FFL+VEA++DAGV +GL+R  A++LA QT+ G+  +L E                   L+
Sbjct  181  FFLMVEAMIDAGVALGLTRPQASELAVQTVKGAGLLLSES-----------------GLS  223

Query  246  ASRLRAAVTSPGGTTAAALRELERGGFRMAVDAA  279
               LRAAVTSP GTTAAALRE ER G R AV+ A
Sbjct  224  PVELRAAVTSPAGTTAAALREFERAGLRHAVNEA  257


>gi|333918306|ref|YP_004491887.1| pyrroline-5-carboxylate reductase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333480527|gb|AEF39087.1| Pyrroline-5-carboxylate reductase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=279

 Score =  230 bits (586),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 138/286 (49%), Positives = 185/286 (65%), Gaps = 12/286 (4%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M  IA+IGGG IGEAL+SGLL +GR+ +D+VV+ER+  RA+ L + + +   S  DA E+
Sbjct  1    MTTIAVIGGGRIGEALISGLLASGREPRDVVVSERVVSRASELCRKFGIRTLSLRDASES  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  VV+A KP DV  V+  L       ++   E+  V++VAG+T  ++E+KLPAGTPVVR
Sbjct  61   ADVVVIATKPGDVGSVVDHLVQVL---DDSDREKTVVSLVAGLTAGWYEAKLPAGTPVVR  117

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LV  G+  +A GR+   + +  V  +   VG V+TV E  +D +TAVSGSGPA
Sbjct  118  VMPNTPMLVNQGMCVVAPGRYAAEEHVALVEEMLRPVGRVMTVREQMMDVITAVSGSGPA  177

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFFL+VEA+ DA V +GL+R  A +L  QTM GSAAML   +  D+GG         V  
Sbjct  178  YFFLVVEAMADAAVKLGLTRDAAMELVVQTMTGSAAMLQRTL--DEGGPA-------VLT  228

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
             A+ LR AVTSPGGTTAA L ELER G R ++  A++AA+ RS +L
Sbjct  229  AANELRYAVTSPGGTTAAGLAELERNGLRTSIFEALEAARDRSVEL  274


>gi|134103385|ref|YP_001109046.1| pyrroline-5-carboxylate reductase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133916008|emb|CAM06121.1| pyrroline-5-carboxylate reductase [Saccharopolyspora erythraea 
NRRL 2338]
Length=301

 Score =  229 bits (584),  Expect = 4e-58, Method: Compositional matrix adjust.
 Identities = 133/289 (47%), Positives = 176/289 (61%), Gaps = 23/289 (7%)

Query  2    LFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADA  61
            L GM  IA++G G IGE+L+SGLL AGR  +DL+  ER P RA  L   Y V     A A
Sbjct  29   LLGMTTIAVLGAGKIGESLMSGLLHAGRSPEDLLFTERYPARAKELTAKYGVEHVDVAGA  88

Query  62   VENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTP  121
            V  A  +VVAVKP D+EP++ ++A    +       ++ V++ AG++ A FE +LP GT 
Sbjct  89   VRRADVIVVAVKPQDIEPLLDEMAADLPSG------KLVVSLCAGLSTALFERRLPEGTR  142

Query  122  VVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGS  181
            VVR MPN   LVG  ++A++ G     + L  V  L  +VG V+ VPESQ DAVTA+SGS
Sbjct  143  VVRVMPNTPMLVGEAMSAISGGEHAEDEHLRLVEELLGSVGKVVRVPESQQDAVTALSGS  202

Query  182  GPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLR  241
            GPAYFF LVEA++DAG+ +G+ R VA DL  Q+  G+AAML      D+G          
Sbjct  203  GPAYFFYLVEAMIDAGILLGIPRAVAADLIVQSAVGAAAML----RSDEG----------  248

Query  242  VDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                   LR AVTSP GTT A +RELE+ G R A+  A++AA+ RS +L
Sbjct  249  ---HPVMLREAVTSPAGTTIAGIRELEKHGVRAALIDAIEAARDRSVEL  294


>gi|291004396|ref|ZP_06562369.1| pyrroline-5-carboxylate reductase [Saccharopolyspora erythraea 
NRRL 2338]
Length=270

 Score =  225 bits (574),  Expect = 6e-57, Method: Compositional matrix adjust.
 Identities = 131/286 (46%), Positives = 174/286 (61%), Gaps = 23/286 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M  IA++G G IGE+L+SGLL AGR  +DL+  ER P RA  L   Y V     A AV  
Sbjct  1    MTTIAVLGAGKIGESLMSGLLHAGRSPEDLLFTERYPARAKELTAKYGVEHVDVAGAVRR  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +VVAVKP D+EP++ ++A    +       ++ V++ AG++ A FE +LP GT VVR
Sbjct  61   ADVIVVAVKPQDIEPLLDEMAADLPSG------KLVVSLCAGLSTALFERRLPEGTRVVR  114

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG  ++A++ G     + L  V  L  +VG V+ VPESQ DAVTA+SGSGPA
Sbjct  115  VMPNTPMLVGEAMSAISGGEHAEDEHLRLVEELLGSVGKVVRVPESQQDAVTALSGSGPA  174

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFF LVEA++DAG+ +G+ R VA DL  Q+  G+AAML      D+G             
Sbjct  175  YFFYLVEAMIDAGILLGIPRAVAADLIVQSAVGAAAML----RSDEG-------------  217

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                LR AVTSP GTT A +RELE+ G R A+  A++AA+ RS +L
Sbjct  218  HPVMLREAVTSPAGTTIAGIRELEKHGVRAALIDAIEAARDRSVEL  263


>gi|117927456|ref|YP_872007.1| pyrroline-5-carboxylate reductase [Acidothermus cellulolyticus 
11B]
 gi|117647919|gb|ABK52021.1| pyrroline-5-carboxylate reductase [Acidothermus cellulolyticus 
11B]
Length=276

 Score =  224 bits (571),  Expect = 1e-56, Method: Compositional matrix adjust.
 Identities = 135/283 (48%), Positives = 176/283 (63%), Gaps = 23/283 (8%)

Query  8    IAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATF  67
            IA++G G +GEAL+SGLL+AG   + LV+ ER P RA  + + Y V   S  +A + A  
Sbjct  13   IAVLGAGKMGEALISGLLKAGLPAEKLVITERYPARAREMTERYQVRAVSNLEAAKTADT  72

Query  68   VVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMP  127
            +V+AVKP D++ ++ +L+ A       + E++ VT+ AGIT +  E +L  G PV+R MP
Sbjct  73   LVLAVKPQDMDDLLTELSPAV------TPERLVVTIAAGITTSAIERRLVEGVPVIRVMP  126

Query  128  NAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFF  187
            N  ALVG  ++ LA G   T + L    A+F  VG VL +PESQLDAVTA+SGSGPAY F
Sbjct  127  NTPALVGEAMSVLAPGSNATEEHLARAEAIFRPVGKVLRLPESQLDAVTALSGSGPAYVF  186

Query  188  LLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTAS  247
             LVEA+ DAG+ +GL R VA DL  QT+ GSA ML E  E                    
Sbjct  187  FLVEAMTDAGILLGLPRSVAHDLIVQTIYGSAVMLRESGEHPVA----------------  230

Query  248  RLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
             LR AVTSPGGTT AA+RELER G R A+ AA++AA+ RS QL
Sbjct  231  -LREAVTSPGGTTIAAIRELERHGVRAALLAALEAARDRSRQL  272


>gi|262200999|ref|YP_003272207.1| pyrroline-5-carboxylate reductase [Gordonia bronchialis DSM 43247]
 gi|262084346|gb|ACY20314.1| pyrroline-5-carboxylate reductase [Gordonia bronchialis DSM 43247]
Length=281

 Score =  221 bits (563),  Expect = 1e-55, Method: Compositional matrix adjust.
 Identities = 127/259 (50%), Positives = 170/259 (66%), Gaps = 20/259 (7%)

Query  18   EALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADV  77
            EALL+GL+ +G   K+LVVAE  P RA  +A  Y VLVT   +A E+A +V +A+KP DV
Sbjct  15   EALLAGLIASGTPTKNLVVAEHSPARAAEIADEYGVLVTDVRNAAESAQYVFLAIKPDDV  74

Query  78   EPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGV  137
            + V+ +LA   AA +N   E+V VT+VAG+ +A +E+ L AG+PV+R MPN   LV   +
Sbjct  75   DGVLRELA---AAQDNAETERVTVTLVAGLPLARYENALQAGSPVIRVMPNTPMLVNEAM  131

Query  138  TALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAG  197
            +A++ GR+V  +QLE V  L   VG V  VPE Q+DAVTA+SGSGPAY FLL E+++DAG
Sbjct  132  SAVSAGRYVAAEQLESVVELLKTVGRVAVVPEKQMDAVTAISGSGPAYVFLLTESMIDAG  191

Query  198  VGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPG  257
            V +GL+R  A+++A QT+ G+  ML      D G            ++   LRAAVTSPG
Sbjct  192  VALGLTRAQASEMAIQTIRGAGIML-----SDAG------------ISPVDLRAAVTSPG  234

Query  258  GTTAAALRELERGGFRMAV  276
            GTTAAA+RE E GG R  V
Sbjct  235  GTTAAAIREFEAGGLRHTV  253


>gi|237786469|ref|YP_002907174.1| pyrroline-5-carboxylate reductase [Corynebacterium kroppenstedtii 
DSM 44385]
 gi|237759381|gb|ACR18631.1| Pyrroline-5-carboxylate reductase [Corynebacterium kroppenstedtii 
DSM 44385]
Length=290

 Score =  220 bits (560),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 129/287 (45%), Positives = 176/287 (62%), Gaps = 21/287 (7%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVL-VTSAADAVE  63
            M +IA+IGGG IGEAL+ GLL       D+VVA R P+R++ L + Y V  V   A AVE
Sbjct  11   MTKIAVIGGGKIGEALIGGLLSGDYDPTDIVVANRRPERSDELKERYGVTAVDDDATAVE  70

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
            NA    + VKP D   V+  +A+     +++  + + V++ AGIT++  E    AGT +V
Sbjct  71   NADIAFLCVKPYDTLGVVESIADVV---DHNDTDTILVSMAAGITLSSLEGIASAGTAIV  127

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG GV  +A+GRFV+ +QLE VS L   +G    V ESQ+DA TAVSGSGP
Sbjct  128  RVMPNTPMLVGKGVNVIARGRFVSDEQLETVSDLLGLLGYTAEVKESQMDAATAVSGSGP  187

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AYFFL++EA+ DAGV +GL R++A +LA+QT  G++ M        Q GA+         
Sbjct  188  AYFFLVLEAMTDAGVNLGLPRELAKELASQTALGASTMAT------QEGAD---------  232

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                +LRA V+SPGGTT+AA R L+  G R A   A++A   +SE+L
Sbjct  233  --PVQLRANVSSPGGTTSAATRALDENGLRTAFYRAMEACAKKSEEL  277


>gi|258651142|ref|YP_003200298.1| pyrroline-5-carboxylate reductase [Nakamurella multipartita DSM 
44233]
 gi|258554367|gb|ACV77309.1| pyrroline-5-carboxylate reductase [Nakamurella multipartita DSM 
44233]
Length=270

 Score =  219 bits (559),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 130/286 (46%), Positives = 168/286 (59%), Gaps = 23/286 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M  IAI+G G IGEALL+GL+ AGR    L+  ER PDR   L + Y V      +A   
Sbjct  1    MTTIAILGAGKIGEALLAGLIGAGRAPDSLMFTERYPDRVAELTERYGVRGVETDEAAAQ  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  ++VAVKP D++P++  LA A           + V++ AG+  A +E  LPAGTPVVR
Sbjct  61   ADVLIVAVKPQDIDPLLQSLATAITPG------TLVVSLCAGLPTALYERHLPAGTPVVR  114

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG  ++A++ G    P  L+ V  L   VG V+ VPESQ DAVTA+SGSGPA
Sbjct  115  VMPNTPMLVGEAMSAISAGSHAEPAHLQLVEDLLSTVGKVVRVPESQQDAVTALSGSGPA  174

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFF LVEA++DAG+ +GL R V+T+L  Q+  G+A ML +  E                 
Sbjct  175  YFFFLVEAMIDAGILLGLPRAVSTELIIQSAVGAATMLRDSGEHP---------------  219

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                LR AVTSPGGTT AA+RELE    R A+  A++AA  RS +L
Sbjct  220  --VTLREAVTSPGGTTIAAIRELENHRVRAALLTAIEAAALRSAEL  263


>gi|257054352|ref|YP_003132184.1| pyrroline-5-carboxylate reductase [Saccharomonospora viridis 
DSM 43017]
 gi|256584224|gb|ACU95357.1| pyrroline-5-carboxylate reductase [Saccharomonospora viridis 
DSM 43017]
Length=270

 Score =  219 bits (558),  Expect = 4e-55, Method: Compositional matrix adjust.
 Identities = 131/286 (46%), Positives = 176/286 (62%), Gaps = 23/286 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M  IA++G G IGEALLSGLL  GR  +DL+  ER P+RA  L   Y +   +  +A   
Sbjct  1    MGTIAVLGAGKIGEALLSGLLSGGRSAEDLLFTERHPERAAELESRYGITNVTIEEAAAR  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +V+AVKP D++PV+A+LA     +       + V++ AG+  + FE +LP  TPVVR
Sbjct  61   ADLLVIAVKPQDIDPVLAELAPLLRPS------SLVVSLCAGLPTSLFERRLPPNTPVVR  114

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG  ++A++ G   T + ++ V+ L   VG V+ VPESQ DAVTA+SGSGPA
Sbjct  115  VMPNTPMLVGEAMSAVSPGSHATREHVQTVTELLSCVGKVVEVPESQQDAVTALSGSGPA  174

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFF LVEA++DAG+ +GL R VA  L  Q+  G+A ML      D+G  +  L       
Sbjct  175  YFFYLVEAMIDAGILLGLPRAVAERLIVQSAVGAAKML------DEGAGHPVL-------  221

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                LR AVTSPGGTT  A+RELE  G R A+ AA++AA+ RS +L
Sbjct  222  ----LREAVTSPGGTTINAIRELENHGVRAALLAAIEAARDRSVEL  263


>gi|343925953|ref|ZP_08765468.1| pyrroline-5-carboxylate reductase [Gordonia alkanivorans NBRC 
16433]
 gi|343764304|dbj|GAA12394.1| pyrroline-5-carboxylate reductase [Gordonia alkanivorans NBRC 
16433]
Length=286

 Score =  217 bits (553),  Expect = 2e-54, Method: Compositional matrix adjust.
 Identities = 127/259 (50%), Positives = 168/259 (65%), Gaps = 20/259 (7%)

Query  18   EALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADV  77
            EALL+GL+ AG   KDLVVAE++  RA+ +A  Y VLVT    A E+A +V +AVKP  V
Sbjct  15   EALLAGLIGAGTPTKDLVVAEKLESRASEIADEYGVLVTDVKTAAESAQYVFLAVKPDAV  74

Query  78   EPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGV  137
            + V+ +LA+A    +N   E+V VT+VAGI +A +ES L AG+PV+R MPN   LV   +
Sbjct  75   DSVLRELASAE---DNAQTERVTVTLVAGIPLARYESALQAGSPVIRVMPNTPMLVNEAM  131

Query  138  TALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAG  197
            +A++ GR+V  +QL  V  +   VG V  VPE Q+DAVTAVSGSGPAY FLL EA++DAG
Sbjct  132  SAVSAGRYVGDEQLRAVVNILKTVGRVAVVPEKQMDAVTAVSGSGPAYVFLLAEAMIDAG  191

Query  198  VGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPG  257
            VG+GL+R  A+++  QT+ G+  +L      D G            ++   LRAAVTSPG
Sbjct  192  VGLGLTRAQASEMTIQTIRGAGVLL-----SDSG------------MSPVDLRAAVTSPG  234

Query  258  GTTAAALRELERGGFRMAV  276
            GTTA A+RE E  G R AV
Sbjct  235  GTTAEAIREFEANGLRHAV  253


>gi|256380726|ref|YP_003104386.1| pyrroline-5-carboxylate reductase [Actinosynnema mirum DSM 43827]
 gi|255925029|gb|ACU40540.1| pyrroline-5-carboxylate reductase [Actinosynnema mirum DSM 43827]
Length=270

 Score =  216 bits (551),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 133/286 (47%), Positives = 175/286 (62%), Gaps = 23/286 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M  IA++G G IGEALLSGLL  GR    L+  E+ P R   L+  Y V   S  DA   
Sbjct  1    MTTIAVLGAGKIGEALLSGLLDGGRDAASLLFTEKHPGRGAELSARYGVEAVSVPDAAAR  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +VVAVKP D+EP++ADLA +         + + V++ AG+  + +ES+LPAGTPVVR
Sbjct  61   ADVLVVAVKPQDIEPLLADLAPSL------KPDTLVVSLCAGLPTSLYESRLPAGTPVVR  114

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN   LVG  ++A++ G     + L  V  L   VG V  VPESQ DAVTA+SGSGPA
Sbjct  115  VMPNTPMLVGKAMSAISPGAHAAEEHLALVEDLLSTVGEVARVPESQQDAVTALSGSGPA  174

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            YFF LVEA++DAG+ +G+ R +A  L  Q+  G+AAML      D+GG +  +       
Sbjct  175  YFFYLVEAMIDAGILLGIPRDLAGRLIIQSAVGAAAML------DEGGQHPVI-------  221

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                LR AVTSP GTT  A+RELE+ G R A+ AA++AA+ RS +L
Sbjct  222  ----LREAVTSPAGTTIMAIRELEKHGVRAALLAAIEAARDRSVEL  263


>gi|284034266|ref|YP_003384197.1| pyrroline-5-carboxylate reductase [Kribbella flavida DSM 17836]
 gi|283813559|gb|ADB35398.1| pyrroline-5-carboxylate reductase [Kribbella flavida DSM 17836]
Length=269

 Score =  215 bits (548),  Expect = 6e-54, Method: Compositional matrix adjust.
 Identities = 128/284 (46%), Positives = 169/284 (60%), Gaps = 23/284 (8%)

Query  7    RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENAT  66
            ++AI+G G +GE LLSGLLRAGR+  DL++ ER  +RA  L + Y V V S  DA   A 
Sbjct  6    QVAILGAGVMGETLLSGLLRAGRRPADLLITERREERATELRERYGVDVVSNVDAAAKAD  65

Query  67   FVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAM  126
             +V+ VKP D+  ++A+++    A       Q  V++ AGIT  + ES+LP G  VVR M
Sbjct  66   TLVLVVKPQDMPELLAEISPVVRAG------QTVVSLAAGITTGFIESRLPDGVAVVRVM  119

Query  127  PNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYF  186
            PN  ALV  G+ A+++G       L     L  A G V+ VPE Q DAVTAVSGSGPAY 
Sbjct  120  PNTPALVDEGMAAISRGAHCDESHLVLAEGLLSATGRVIRVPEKQQDAVTAVSGSGPAYL  179

Query  187  FLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTA  246
            F +VEA+++AGV +GL R  AT+L  QT+ GSA +L E  E                   
Sbjct  180  FFVVEAMIEAGVHMGLPRSTATELVVQTVVGSAKLLRETGEH-----------------P  222

Query  247  SRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
            + LR  VTSPGGTTAAA+RELE    R A  +A++AA++RS  L
Sbjct  223  TVLRERVTSPGGTTAAAVRELEDHKVRAAFLSAIEAARNRSRDL  266


>gi|336326504|ref|YP_004606470.1| Pyrroline-5-carboxylate reductase [Corynebacterium resistens 
DSM 45100]
 gi|336102486|gb|AEI10306.1| Pyrroline-5-carboxylate reductase [Corynebacterium resistens 
DSM 45100]
Length=273

 Score =  214 bits (546),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 129/274 (48%), Positives = 163/274 (60%), Gaps = 16/274 (5%)

Query  18   EALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVT-SAADAVENATFVVVAVKPAD  76
            EALLSG++  G   K ++VA+R  +R +YL   Y V+ T  A +A E   ++   VKP  
Sbjct  14   EALLSGIIADGGDAKKVIVADRTQERLDYLKDKYGVVTTLEAVEAAEGVDYLFNCVKPDG  73

Query  77   VEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAG  136
            + PV  ++A+     +++  E V V+V AG+T+   E  LPAGTPVVR MPN   LVG G
Sbjct  74   IVPVFQEVADVL---DDNDEETVVVSVAAGVTLEAMEGALPAGTPVVRIMPNTPMLVGKG  130

Query  137  VTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDA  196
             +ALA GRF     LE V  +   VG  + V E  LDAVTAVSGSGPAYFFL VEALVDA
Sbjct  131  TSALAGGRFAEESHLEGVQNIMGKVGTAVVVKEKDLDAVTAVSGSGPAYFFLAVEALVDA  190

Query  197  GVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSP  256
            GV  GL R +A  LA  T+ G+AAM++   E++ G               S LRA VTSP
Sbjct  191  GVQQGLPRPLAEQLAVSTIEGAAAMMVRGQEEEDGDG------------PSELRAKVTSP  238

Query  257  GGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
            GGTTAAALR LE  G R A   A +A  +RS +L
Sbjct  239  GGTTAAALRALEENGLRKAFFHAAEACANRSREL  272


>gi|311896780|dbj|BAJ29188.1| putative pyrroline-5-carboxylate reductase [Kitasatospora setae 
KM-6054]
Length=275

 Score =  213 bits (542),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 125/284 (45%), Positives = 174/284 (62%), Gaps = 23/284 (8%)

Query  7    RIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENAT  66
            +IA +G G IGEALLSGLLRAG    D++V  R  +RA  LA  + V V + A+A + A 
Sbjct  10   KIAFLGTGKIGEALLSGLLRAGTSPADVLVTARRAERATELADRHGVTVVTNAEAAKLAD  69

Query  67   FVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAM  126
             +++AVKP D+  ++ +LA      E+ +A+++ V+  AGI  ++FE +L  GTPVVR M
Sbjct  70   TLILAVKPQDMGTLLDELA------EHVAADKLVVSAAAGIPTSWFEERLAPGTPVVRVM  123

Query  127  PNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYF  186
            PN   LV  G++ ++ G       L    A+F +VG  L VPESQ DA TA+SGSGPAYF
Sbjct  124  PNTPVLVDEGMSVISGGSHAAEAHLLRAEAIFRSVGKALRVPESQQDAATALSGSGPAYF  183

Query  187  FLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTA  246
            + LVEA++DAG+ +GL RQVA +L  Q+  G++ ML +  E                   
Sbjct  184  YFLVEAMIDAGILLGLPRQVAHELIVQSAIGASVMLRDSGEH-----------------P  226

Query  247  SRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
             +LR AVTSP GTT AA+RELE  G R A+  A++AA+ RS +L
Sbjct  227  VKLREAVTSPAGTTIAAIRELENHGVRAAMLGALEAARDRSREL  270


>gi|302523825|ref|ZP_07276167.1| pyrroline-5-carboxylate reductase [Streptomyces sp. AA4]
 gi|302432720|gb|EFL04536.1| pyrroline-5-carboxylate reductase [Streptomyces sp. AA4]
Length=273

 Score =  213 bits (541),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 128/287 (45%), Positives = 171/287 (60%), Gaps = 24/287 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYS-VLVTSAADAVE  63
            M+ IA++G G IGEALLSGLL  G +  DL+  ER  +RA  L   Y  +   + ADA  
Sbjct  4    MSVIAVLGAGKIGEALLSGLLNGGHEPGDLLFTERYEERARELETRYPGMKAATVADAAR  63

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
             A  +VVAVKP D+EPV+ +LA             + V++ AG+  A +E +L  G PVV
Sbjct  64   RADILVVAVKPQDIEPVLDELAPLLGTG------SLVVSLCAGLPTALYERRLAEGVPVV  117

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG  ++A++ G+  T + L  V  L   VG V+ VPE Q DAVTA+SGSGP
Sbjct  118  RVMPNTPMLVGEAMSAISPGKHATVEHLATVKELLSHVGQVVEVPERQQDAVTALSGSGP  177

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AYFF LVEA++DAG+ +GL R +A  L  Q+  G+A ML E       G +  ++     
Sbjct  178  AYFFYLVEAMIDAGILLGLPRALAGQLIIQSAVGAAKMLAE-------GQDHPVL-----  225

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                 LR AVTSP GTT  A+RELE+ G R A+  A++AA+ RSE+L
Sbjct  226  -----LREAVTSPAGTTINAIRELEKHGVRAALLDAIEAARDRSEEL  267


>gi|225020266|ref|ZP_03709458.1| hypothetical protein CORMATOL_00269 [Corynebacterium matruchotii 
ATCC 33806]
 gi|224947010|gb|EEG28219.1| hypothetical protein CORMATOL_00269 [Corynebacterium matruchotii 
ATCC 33806]
Length=273

 Score =  211 bits (538),  Expect = 8e-53, Method: Compositional matrix adjust.
 Identities = 129/291 (45%), Positives = 172/291 (60%), Gaps = 22/291 (7%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLV-TSAA  59
            M+  M+ IA+IGGG IGEAL+ GL+  G   K++ V  R P+R  YL   Y+VL      
Sbjct  1    MVEFMSSIAVIGGGKIGEALIVGLINGGINPKNIHVTNREPERNQYLRDKYAVLTFDDNI  60

Query  60   DAVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAG  119
             AV+ A  V + VKP  V  V+ ++++     +N+ A  V V++ AGI+IA  E  L AG
Sbjct  61   LAVDGADVVFLCVKPKVVASVVEEISDRI---DNNEATTV-VSMAAGISIAVVEEGLAAG  116

Query  120  TPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVS  179
             PV+R MPN   LVGAG+ A+A GRFV  +QL  V  L   VG V  V E  +DAVTA+S
Sbjct  117  APVIRVMPNTPMLVGAGMCAMAVGRFVEAEQLARVKDLLSMVGAVRVVDEHDMDAVTAMS  176

Query  180  GSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMG  239
            GS PAY FLLVEA++DAGV +GL+R  A +L+  T  G+A MLL+   +           
Sbjct  177  GSAPAYLFLLVEAMIDAGVNLGLTRDAARELSTMTFYGAAKMLLDTSAE-----------  225

Query  240  LRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                   + LRA V+SPGG+T AA+RE E  G R AV  A +A   RS++L
Sbjct  226  ------PAELRANVSSPGGSTIAAIREFEEAGLRAAVYRATEACAHRSKEL  270


>gi|305679732|ref|ZP_07402542.1| pyrroline-5-carboxylate reductase [Corynebacterium matruchotii 
ATCC 14266]
 gi|305660352|gb|EFM49849.1| pyrroline-5-carboxylate reductase [Corynebacterium matruchotii 
ATCC 14266]
Length=273

 Score =  211 bits (537),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 129/291 (45%), Positives = 172/291 (60%), Gaps = 22/291 (7%)

Query  1    MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLV-TSAA  59
            M+  M+ IA+IGGG IGEAL+ GL+  G   K++ V  R P+R  YL   Y+VL      
Sbjct  1    MVEFMSSIAVIGGGKIGEALIVGLINGGINPKNIHVTNREPERNQYLRDKYAVLTFDDNI  60

Query  60   DAVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAG  119
             AV+ A  V + VKP  V  V+ ++++     +N+ A  V V++ AGI+IA  E  L AG
Sbjct  61   LAVDGADVVFLCVKPKVVASVVEEISDRI---DNNEATTV-VSMAAGISIAVVEEGLAAG  116

Query  120  TPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVS  179
             PV+R MPN   LVGAG+ A+A GRFV  +QL  V  L   VG V  V E  +DAVTA+S
Sbjct  117  APVIRVMPNTPMLVGAGMCAMAVGRFVEAEQLARVKDLLSMVGAVRVVDEHDMDAVTAMS  176

Query  180  GSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMG  239
            GS PAY FLLVEA++DAGV +GL+R  A +L+  T  G+A MLL+   +           
Sbjct  177  GSAPAYLFLLVEAMIDAGVNLGLTRDAARELSTMTFYGAAKMLLDTSAE-----------  225

Query  240  LRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
                   + LRA V+SPGG+T AA+RE E  G R AV  A +A   RS++L
Sbjct  226  ------PAELRANVSSPGGSTIAAIREFEEAGLRAAVYRATEACARRSKEL  270


>gi|97180300|sp|P0C1E5.1|P5CR_CORML RecName: Full=Pyrroline-5-carboxylate reductase; Short=P5C reductase; 
Short=P5CR
 gi|950193|gb|AAC44172.1| L-proline:NADP+ 5-oxidoreductase [Corynebacterium glutamicum]
Length=270

 Score =  211 bits (536),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 126/287 (44%), Positives = 169/287 (59%), Gaps = 21/287 (7%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVL-VTSAADAVE  63
            M  IA+IGGG IGEAL+SGL+ A    +++ V  R  +R   L   Y +L +T  + A +
Sbjct  1    MTTIAVIGGGQIGEALVSGLIAANMNPQNIRVTNRSEERGQELRDRYGILNMTDNSQAAD  60

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
             A  V + VKP  +  V++++   T   +N+SA+ V V++ AGI+IA  E    AG PVV
Sbjct  61   EADVVFLCVKPKFIVEVLSEI---TGTLDNNSAQSVVVSMAAGISIAAMEESASAGLPVV  117

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG G++ + KGR+V  +QLE+V  L   VG VL V ES +DAVTA+SGS P
Sbjct  118  RVMPNTPMLVGKGMSTVTKGRYVDAEQLEQVKDLLSTVGDVLEVAESDIDAVTAMSGSSP  177

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AY FL+ EAL++AGV +GL R  A  LA  +  G+A M+ E  ++               
Sbjct  178  AYLFLVTEALIEAGVNLGLPRATAKKLAVASFEGAATMMKETGKE---------------  222

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
               S LRA V+SP GTT AA+RELE  G R A   A QA   RSE+L
Sbjct  223  --PSELRAGVSSPAGTTVAAIRELEESGIRGAFYRAAQACADRSEEL  267


>gi|72163107|ref|YP_290764.1| pyrroline-5-carboxylate reductase [Thermobifida fusca YX]
 gi|71916839|gb|AAZ56741.1| pyrroline-5-carboxylate reductase [Thermobifida fusca YX]
Length=264

 Score =  211 bits (536),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 134/283 (48%), Positives = 171/283 (61%), Gaps = 23/283 (8%)

Query  8    IAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATF  67
            IAIIG G +GEALL+G+L  GR   +++++E   DRA  L Q Y V   S A+A   A  
Sbjct  2    IAIIGAGRMGEALLAGILHTGRDAAEVLISEAREDRAAELCQRYGVAAASPAEAAARADT  61

Query  68   VVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMP  127
            +++AVKP D+   + ++A A          ++ ++V AGIT A  E  LPA T VVRAMP
Sbjct  62   LLLAVKPQDMVAALNEIAPALPPG------RLVISVAAGITTAVLEKHLPAETAVVRAMP  115

Query  128  NAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFF  187
            N  ALVG G+TA+A G     + L+    L  +VG V+ VPE  LDAVTA+SGSGPAYF+
Sbjct  116  NTPALVGQGMTAIAAGTHTLEEHLDRAETLLRSVGEVVRVPEKHLDAVTALSGSGPAYFY  175

Query  188  LLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTAS  247
            L+ EA+++AGV +GL R  A  L  QT  GSAAML     +D G               +
Sbjct  176  LVAEAMIEAGVLLGLPRPTAERLVTQTAVGSAAML-----RDSGD------------HPT  218

Query  248  RLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
             LR AVTSPGGTTAAALRELER G R A   AV+AA  RS +L
Sbjct  219  LLREAVTSPGGTTAAALRELERHGLRSAFADAVEAACRRSAEL  261


>gi|19551656|ref|NP_599658.1| pyrroline-5-carboxylate reductase [Corynebacterium glutamicum 
ATCC 13032]
 gi|145294528|ref|YP_001137349.1| pyrroline-5-carboxylate reductase [Corynebacterium glutamicum 
R]
 gi|140844448|dbj|BAF53447.1| hypothetical protein [Corynebacterium glutamicum R]
Length=273

 Score =  211 bits (536),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 126/287 (44%), Positives = 169/287 (59%), Gaps = 21/287 (7%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVL-VTSAADAVE  63
            M  IA+IGGG IGEAL+SGL+ A    +++ V  R  +R   L   Y +L +T  + A +
Sbjct  4    MTTIAVIGGGQIGEALVSGLIAANMNPQNIRVTNRSEERGQELRDRYGILNMTDNSQAAD  63

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
             A  V + VKP  +  V++++   T   +N+SA+ V V++ AGI+IA  E    AG PVV
Sbjct  64   EADVVFLCVKPKFIVEVLSEI---TGTLDNNSAQSVVVSMAAGISIAAMEESASAGLPVV  120

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG G++ + KGR+V  +QLE+V  L   VG VL V ES +DAVTA+SGS P
Sbjct  121  RVMPNTPMLVGKGMSTVTKGRYVDAEQLEQVKDLLSTVGDVLEVAESDIDAVTAMSGSSP  180

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AY FL+ EAL++AGV +GL R  A  LA  +  G+A M+ E  ++               
Sbjct  181  AYLFLVTEALIEAGVNLGLPRATAKKLAVASFEGAATMMKETGKE---------------  225

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
               S LRA V+SP GTT AA+RELE  G R A   A QA   RSE+L
Sbjct  226  --PSELRAGVSSPAGTTVAAIRELEESGIRGAFYRAAQACADRSEEL  270


>gi|62389310|ref|YP_224712.1| pyrroline-5-carboxylate reductase [Corynebacterium glutamicum 
ATCC 13032]
 gi|97180299|sp|P0C1E4.1|P5CR_CORGL RecName: Full=Pyrroline-5-carboxylate reductase; Short=P5C reductase; 
Short=P5CR
 gi|21323175|dbj|BAB97803.1| Pyrroline-5-carboxylate reductase [Corynebacterium glutamicum 
ATCC 13032]
 gi|41324644|emb|CAF19126.1| PYRROLINE-5-CARBOXYLATE REDUCTASE [Corynebacterium glutamicum 
ATCC 13032]
 gi|344045327|gb|EGV40999.1| pyrroline-5-carboxylate reductase [Corynebacterium glutamicum 
S9114]
Length=270

 Score =  211 bits (536),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 126/287 (44%), Positives = 169/287 (59%), Gaps = 21/287 (7%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVL-VTSAADAVE  63
            M  IA+IGGG IGEAL+SGL+ A    +++ V  R  +R   L   Y +L +T  + A +
Sbjct  1    MTTIAVIGGGQIGEALVSGLIAANMNPQNIRVTNRSEERGQELRDRYGILNMTDNSQAAD  60

Query  64   NATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVV  123
             A  V + VKP  +  V++++   T   +N+SA+ V V++ AGI+IA  E    AG PVV
Sbjct  61   EADVVFLCVKPKFIVEVLSEI---TGTLDNNSAQSVVVSMAAGISIAAMEESASAGLPVV  117

Query  124  RAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGP  183
            R MPN   LVG G++ + KGR+V  +QLE+V  L   VG VL V ES +DAVTA+SGS P
Sbjct  118  RVMPNTPMLVGKGMSTVTKGRYVDAEQLEQVKDLLSTVGDVLEVAESDIDAVTAMSGSSP  177

Query  184  AYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVD  243
            AY FL+ EAL++AGV +GL R  A  LA  +  G+A M+ E  ++               
Sbjct  178  AYLFLVTEALIEAGVNLGLPRATAKKLAVASFEGAATMMKETGKE---------------  222

Query  244  LTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
               S LRA V+SP GTT AA+RELE  G R A   A QA   RSE+L
Sbjct  223  --PSELRAGVSSPAGTTVAAIRELEESGIRGAFYRAAQACADRSEEL  267


>gi|297563917|ref|YP_003682890.1| pyrroline-5-carboxylate reductase [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
 gi|296848366|gb|ADH70384.1| pyrroline-5-carboxylate reductase [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
Length=264

 Score =  210 bits (535),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 127/283 (45%), Positives = 168/283 (60%), Gaps = 23/283 (8%)

Query  8    IAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATF  67
            IAIIG G +GEALL+G+L  G   +D++V E   + A  L   Y + V  AADA + A  
Sbjct  2    IAIIGAGKMGEALLAGMLATGHAPEDVLVTEPREEHAGELRARYGIEVVPAADAAKRADT  61

Query  68   VVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMP  127
            +++A+KP D+  ++ DLA         S+  + ++V AGIT A  E  LP+GTPVVRAMP
Sbjct  62   LLLALKPQDMVALLDDLA------PRLSSSCLVISVAAGITTAVLEEHLPSGTPVVRAMP  115

Query  128  NAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFF  187
            N  AL+G G+TA+A G       L+   AL   VG V+ V E  +D VTA+SGSGPAYF+
Sbjct  116  NTPALMGQGMTAIAGGAHTGEAHLDRAEALLGTVGDVIRVGEQHMDTVTAISGSGPAYFY  175

Query  188  LLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDLTAS  247
             + E +++AGV +G+ R  A  L  QT+ G+AAML           +GE           
Sbjct  176  FIAETMIEAGVAMGMPRATAQKLVGQTITGAAAML---------NGSGE--------HPV  218

Query  248  RLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
             LR AVTSPGGTTAAALRELER G R A   A++AA+ RS  L
Sbjct  219  VLREAVTSPGGTTAAALRELERHGVRTAFTDAIEAARDRSNAL  261


>gi|317123802|ref|YP_004097914.1| pyrroline-5-carboxylate reductase [Intrasporangium calvum DSM 
43043]
 gi|315587890|gb|ADU47187.1| pyrroline-5-carboxylate reductase [Intrasporangium calvum DSM 
43043]
Length=268

 Score =  208 bits (529),  Expect = 8e-52, Method: Compositional matrix adjust.
 Identities = 123/286 (44%), Positives = 166/286 (59%), Gaps = 23/286 (8%)

Query  5    MARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVEN  64
            M   AI G G +GE LLSGLLR+GR   DL++ ER  +RA  LA+ Y V V    +A + 
Sbjct  1    MGTTAIFGAGVMGETLLSGLLRSGRAAADLIITERNAERAAQLAEKYDVRVLPNTEAADL  60

Query  65   ATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVR  124
            A  +V+ VKP D+E ++A++ +              V++ AGIT  + ES LP G+ VVR
Sbjct  61   ADTLVLVVKPQDMEGLLAEIRDHVRDG------NTVVSLAAGITTEFLESHLPEGSSVVR  114

Query  125  AMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPA  184
             MPN  ALV  G+  ++ GR  T   L E  AL  + G V+ + E  LDAVTA+SGSGPA
Sbjct  115  VMPNTPALVDQGMAGVSPGRHCTEDHLLEAEALLSSCGKVVRLEEKHLDAVTAISGSGPA  174

Query  185  YFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMEQDQGGANGELMGLRVDL  244
            Y F +VEA+++AGV +GL R  AT+L  QT+ G+A ML E  E                 
Sbjct  175  YIFYVVEAMIEAGVVLGLPRATATELVVQTLYGAATMLKETHEH----------------  218

Query  245  TASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQL  290
              + LR  V+SPGGTT AALR+L+    R A   A++AA +RS+QL
Sbjct  219  -PTVLREQVSSPGGTTVAALRQLDDHKVRAAFVNAMEAAAARSKQL  263



Lambda     K      H
   0.317    0.130    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 489554810128




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40