BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0516c
Length=158
Score E
Sequences producing significant alignments: (Bits) Value
gi|15839909|ref|NP_334946.1| hypothetical protein MT0537 [Mycoba... 324 3e-87
gi|15607657|ref|NP_215030.1| hypothetical protein Rv0516c [Mycob... 324 3e-87
gi|308371695|ref|ZP_07667223.1| LOW QUALITY PROTEIN: hypothetica... 286 7e-76
gi|308231575|ref|ZP_07663882.1| hypothetical protein TMAG_03519 ... 241 2e-62
gi|333990636|ref|YP_004523250.1| hypothetical protein JDM601_199... 166 1e-39
gi|240173366|ref|ZP_04752024.1| hypothetical protein MkanA1_2889... 162 2e-38
gi|118616416|ref|YP_904748.1| hypothetical protein MUL_0605 [Myc... 155 2e-36
gi|118462779|ref|YP_883763.1| STAS domain-containing protein [My... 152 2e-35
gi|41410105|ref|NP_962941.1| hypothetical protein MAP4007c [Myco... 151 3e-35
gi|254821053|ref|ZP_05226054.1| STAS domain-containing protein [... 150 4e-35
gi|342858980|ref|ZP_08715634.1| STAS domain-containing protein [... 150 5e-35
gi|296168174|ref|ZP_06850195.1| anti-sigma-factor antagonist [My... 149 1e-34
gi|145220947|ref|YP_001131625.1| anti-sigma-factor antagonist [M... 106 1e-21
gi|120401420|ref|YP_951249.1| anti-sigma-factor antagonist [Myco... 105 1e-21
gi|118469263|ref|YP_884997.1| STAS domain-containing protein [My... 90.5 7e-17
gi|108797339|ref|YP_637536.1| anti-sigma-factor antagonist [Myco... 85.9 2e-15
gi|240169577|ref|ZP_04748236.1| stas domain-containing protein [... 82.0 2e-14
gi|296169161|ref|ZP_06850816.1| stas domain protein [Mycobacteri... 70.9 7e-11
gi|118464299|ref|YP_883045.1| stas domain-containing protein [My... 65.5 3e-09
gi|254776304|ref|ZP_05217820.1| hypothetical protein MaviaA2_167... 65.1 3e-09
gi|342858142|ref|ZP_08714797.1| stas domain-containing protein [... 64.7 5e-09
gi|254821742|ref|ZP_05226743.1| stas domain-containing protein [... 63.5 1e-08
gi|296169142|ref|ZP_06850798.1| anti-sigma-factor antagonist [My... 63.2 1e-08
gi|41409166|ref|NP_962002.1| hypothetical protein MAP3068 [Mycob... 62.8 2e-08
gi|108797874|ref|YP_638071.1| anti-sigma-factor antagonist [Myco... 60.1 9e-08
gi|342861500|ref|ZP_08718147.1| hypothetical protein MCOL_21546 ... 56.6 1e-06
gi|254819524|ref|ZP_05224525.1| hypothetical protein MintA_06344... 56.6 1e-06
gi|145224460|ref|YP_001135138.1| anti-sigma-factor antagonist [M... 56.2 2e-06
gi|315444795|ref|YP_004077674.1| anti-anti-sigma regulatory fact... 56.2 2e-06
gi|118464650|ref|YP_883397.1| STAS domain-containing protein [My... 55.1 3e-06
gi|254776691|ref|ZP_05218207.1| hypothetical protein MaviaA2_187... 55.1 3e-06
gi|41409503|ref|NP_962339.1| hypothetical protein MAP3405 [Mycob... 55.1 3e-06
gi|336459632|gb|EGO38567.1| anti-anti-sigma regulatory factor (a... 55.1 4e-06
gi|296168914|ref|ZP_06850583.1| anti-sigma-factor antagonist [My... 55.1 4e-06
gi|240171603|ref|ZP_04750262.1| hypothetical protein MkanA1_1997... 53.5 1e-05
gi|315445713|ref|YP_004078592.1| STAS domain-containing protein ... 52.8 2e-05
gi|145225366|ref|YP_001136044.1| anti-sigma-factor antagonist [M... 52.4 2e-05
gi|126433913|ref|YP_001069604.1| anti-sigma-factor antagonist [M... 52.4 2e-05
gi|120405652|ref|YP_955481.1| anti-sigma-factor antagonist [Myco... 52.0 3e-05
gi|108798253|ref|YP_638450.1| anti-sigma-factor antagonist [Myco... 51.6 4e-05
gi|145222611|ref|YP_001133289.1| anti-sigma-factor antagonist [M... 50.1 1e-04
gi|120402667|ref|YP_952496.1| anti-sigma-factor antagonist [Myco... 49.3 2e-04
gi|315443076|ref|YP_004075955.1| anti-anti-sigma regulatory fact... 49.3 2e-04
gi|333991689|ref|YP_004524303.1| anti-sigma-factor antagonist [M... 48.9 2e-04
gi|169629598|ref|YP_001703247.1| hypothetical protein MAB_2512 [... 48.9 2e-04
gi|108799864|ref|YP_640061.1| anti-sigma-factor antagonist [Myco... 48.5 3e-04
gi|120403518|ref|YP_953347.1| anti-sigma-factor antagonist [Myco... 47.4 7e-04
gi|145220808|ref|YP_001131486.1| anti-sigma-factor antagonist [M... 47.0 0.001
gi|120401717|ref|YP_951546.1| anti-sigma-factor antagonist [Myco... 47.0 0.001
gi|148270482|ref|YP_001244942.1| anti-sigma-factor antagonist [T... 47.0 0.001
>gi|15839909|ref|NP_334946.1| hypothetical protein MT0537 [Mycobacterium tuberculosis CDC1551]
gi|13880046|gb|AAK44760.1| hypothetical protein MT0537 [Mycobacterium tuberculosis CDC1551]
gi|323721055|gb|EGB30118.1| hypothetical protein TMMG_03892 [Mycobacterium tuberculosis CDC1551A]
gi|339293563|gb|AEJ45674.1| hypothetical protein CCDC5079_0484 [Mycobacterium tuberculosis
CCDC5079]
gi|339297204|gb|AEJ49314.1| hypothetical protein CCDC5180_0477 [Mycobacterium tuberculosis
CCDC5180]
Length=159
Score = 324 bits (831), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 158/158 (100%), Positives = 158/158 (100%), Gaps = 0/158 (0%)
Query 1 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR 60
MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR
Sbjct 2 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR 61
Query 61 RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG 120
RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG
Sbjct 62 RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG 121
Query 121 EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 158
EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA
Sbjct 122 EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 159
>gi|15607657|ref|NP_215030.1| hypothetical protein Rv0516c [Mycobacterium tuberculosis H37Rv]
gi|31791698|ref|NP_854191.1| hypothetical protein Mb0529c [Mycobacterium bovis AF2122/97]
gi|121636434|ref|YP_976657.1| hypothetical protein BCG_0559c [Mycobacterium bovis BCG str.
Pasteur 1173P2]
53 more sequence titles
Length=158
Score = 324 bits (830), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 158/158 (100%), Positives = 158/158 (100%), Gaps = 0/158 (0%)
Query 1 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR 60
MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR
Sbjct 1 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR 60
Query 61 RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG 120
RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG
Sbjct 61 RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG 120
Query 121 EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 158
EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA
Sbjct 121 EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 158
>gi|308371695|ref|ZP_07667223.1| LOW QUALITY PROTEIN: hypothetical protein TMDG_02999 [Mycobacterium
tuberculosis SUMu004]
gi|308335790|gb|EFP24641.1| LOW QUALITY PROTEIN: hypothetical protein TMDG_02999 [Mycobacterium
tuberculosis SUMu004]
Length=140
Score = 286 bits (732), Expect = 7e-76, Method: Compositional matrix adjust.
Identities = 140/140 (100%), Positives = 140/140 (100%), Gaps = 0/140 (0%)
Query 19 GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH 78
GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH
Sbjct 1 GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH 60
Query 79 FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD 138
FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD
Sbjct 61 FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD 120
Query 139 LADAIDRRRQLVLPLISRSA 158
LADAIDRRRQLVLPLISRSA
Sbjct 121 LADAIDRRRQLVLPLISRSA 140
>gi|308231575|ref|ZP_07663882.1| hypothetical protein TMAG_03519 [Mycobacterium tuberculosis SUMu001]
gi|308369417|ref|ZP_07417706.2| hypothetical protein TMBG_03753 [Mycobacterium tuberculosis SUMu002]
gi|308370433|ref|ZP_07666927.1| hypothetical protein TMCG_03346 [Mycobacterium tuberculosis SUMu003]
17 more sequence titles
Length=119
Score = 241 bits (616), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 118/119 (99%), Positives = 119/119 (100%), Gaps = 0/119 (0%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV
Sbjct 1 MVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 60
Query 100 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 158
QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA
Sbjct 61 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 119
>gi|333990636|ref|YP_004523250.1| hypothetical protein JDM601_1996 [Mycobacterium sp. JDM601]
gi|333486604|gb|AEF35996.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=152
Score = 166 bits (419), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 87/158 (56%), Positives = 111/158 (71%), Gaps = 6/158 (3%)
Query 1 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR 60
M TI T++SA + + GN V G AQIRA+ HLATV+TIRG ID++NV+++SEH R
Sbjct 1 MAITI-TTRSAARIGQQ-GNPTVKCGDAQIRAHSRHLATVITIRGRIDSSNVDELSEHAR 58
Query 61 RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG 120
RF L P++LDLS ++ F+ AGI LLC+LD DCRAAGV W L+ PAV E LG
Sbjct 59 RFVLAKEPLLLDLSGVTSFAAAGIWLLCVLDGDCRAAGVDWTLIEGPAVSELLG----DF 114
Query 121 EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA 158
+ ++MFP ARSV +ALH LAD DRRRQ +LPL +SA
Sbjct 115 DEDAMFPTARSVEQALHALADGNDRRRQALLPLFQKSA 152
>gi|240173366|ref|ZP_04752024.1| hypothetical protein MkanA1_28896 [Mycobacterium kansasii ATCC
12478]
Length=149
Score = 162 bits (409), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 84/144 (59%), Positives = 109/144 (76%), Gaps = 4/144 (2%)
Query 15 TTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLS 74
T R GN D GA IRA+ HLATVVTIRG+IDA N++++ ++++RF L +P+VLDLS
Sbjct 10 TGRRGNWTYDCAGAHIRAHCRHLATVVTIRGDIDAVNIDEVGKYLQRFILEDHPVVLDLS 69
Query 75 ELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHK 134
E+ +FS A ISLL +LDE+C AAGVQW+LVASPAV + LG D +++FP+ SVH+
Sbjct 70 EVDYFSAAAISLLHMLDENCHAAGVQWSLVASPAVRQLLGDDRD----DALFPLTGSVHE 125
Query 135 ALHDLADAIDRRRQLVLPLISRSA 158
AL DLADAI RRQLVLPLI ++A
Sbjct 126 ALRDLADAIVSRRQLVLPLIRKTA 149
>gi|118616416|ref|YP_904748.1| hypothetical protein MUL_0605 [Mycobacterium ulcerans Agy99]
gi|183980875|ref|YP_001849166.1| hypothetical protein MMAR_0853 [Mycobacterium marinum M]
gi|118568526|gb|ABL03277.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
gi|183174201|gb|ACC39311.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=149
Score = 155 bits (393), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 79/149 (54%), Positives = 106/149 (72%), Gaps = 5/149 (3%)
Query 10 SACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPM 69
+A S R N + GA +RA+ HLAT+VTIRGEIDA NV+Q++E ++ F GTNP+
Sbjct 6 TASSFADRQKNGTFECSGAVVRAHCRHLATIVTIRGEIDAVNVDQVTERIQHFIHGTNPV 65
Query 70 VLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMA 129
VLD+ ++SHFS AGISLL +DE+C AAG +W LVA PAVVE LG + +MFP+A
Sbjct 66 VLDVGDVSHFSPAGISLLAAIDEECHAAGAEWTLVAGPAVVELLG-----EDMATMFPVA 120
Query 130 RSVHKALHDLADAIDRRRQLVLPLISRSA 158
SVH+AL +LA+A RRQL+L L+ ++A
Sbjct 121 HSVHEALRNLAEANSSRRQLMLSLVRKTA 149
>gi|118462779|ref|YP_883763.1| STAS domain-containing protein [Mycobacterium avium 104]
gi|254777071|ref|ZP_05218587.1| STAS domain-containing protein [Mycobacterium avium subsp. avium
ATCC 25291]
gi|118164066|gb|ABK64963.1| stas domain, putative [Mycobacterium avium 104]
Length=146
Score = 152 bits (383), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 78/143 (55%), Positives = 101/143 (71%), Gaps = 4/143 (2%)
Query 16 TRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSE 75
TR N D GAQ+RA+ HLATVV IRG ID ANV++IS H+RRF+LG NP+VLD+++
Sbjct 8 TRHDNCVFDCDGAQVRAHHRHLATVVHIRGVIDDANVDRISHHIRRFTLGENPVVLDVAD 67
Query 76 LSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKA 135
+S F+ AGISLL D DCRAA V+W LVAS AV L D H++ FP+ RSVH+
Sbjct 68 VSQFAEAGISLLYAFDADCRAAEVEWTLVASSAVTAVL----DDTGHDASFPIMRSVHEV 123
Query 136 LHDLADAIDRRRQLVLPLISRSA 158
L D ADAI RR++ LPL+ +++
Sbjct 124 LRDRADAIAVRRRMALPLVKKTS 146
>gi|41410105|ref|NP_962941.1| hypothetical protein MAP4007c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398938|gb|AAS06557.1| hypothetical protein MAP_4007c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336460518|gb|EGO39413.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium avium subsp. paratuberculosis S397]
Length=146
Score = 151 bits (381), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 77/143 (54%), Positives = 101/143 (71%), Gaps = 4/143 (2%)
Query 16 TRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSE 75
TR N D GAQ+RA+ HLATVV IRG ID ANV++IS H+RRF+LG NP+VLD+++
Sbjct 8 TRHDNCVFDCDGAQVRAHHRHLATVVHIRGVIDDANVDRISHHIRRFTLGENPVVLDVAD 67
Query 76 LSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKA 135
++ F+ AGISLL D DCRAA V+W LVAS AV L D H++ FP+ RSVH+
Sbjct 68 VTQFAEAGISLLYAFDADCRAAEVEWTLVASSAVTAVL----DDTGHDASFPIMRSVHEV 123
Query 136 LHDLADAIDRRRQLVLPLISRSA 158
L D ADAI RR++ LPL+ +++
Sbjct 124 LRDRADAIAVRRRMALPLVKKTS 146
>gi|254821053|ref|ZP_05226054.1| STAS domain-containing protein [Mycobacterium intracellulare
ATCC 13950]
Length=146
Score = 150 bits (380), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 77/143 (54%), Positives = 102/143 (72%), Gaps = 4/143 (2%)
Query 16 TRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSE 75
+R N + GAQ+RA+ HLATVV IRGEID NV+++S H+RRF+LG NP+VLD+++
Sbjct 8 SRHDNCVFECDGAQVRAHYRHLATVVHIRGEIDDTNVDRVSRHIRRFTLGENPVVLDVAD 67
Query 76 LSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKA 135
+S F+ AGISLL D DCRAAGV W LVAS AV+ L D G H++ FP+ RSV +A
Sbjct 68 VSQFAEAGISLLYAFDADCRAAGVDWTLVASSAVIAVLE---DTG-HDANFPLMRSVQEA 123
Query 136 LHDLADAIDRRRQLVLPLISRSA 158
L D ADAI RR + LPL+ +++
Sbjct 124 LRDRADAIRVRRTMALPLVRKTS 146
>gi|342858980|ref|ZP_08715634.1| STAS domain-containing protein [Mycobacterium colombiense CECT
3035]
gi|342133221|gb|EGT86424.1| STAS domain-containing protein [Mycobacterium colombiense CECT
3035]
Length=146
Score = 150 bits (379), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 77/138 (56%), Positives = 99/138 (72%), Gaps = 4/138 (2%)
Query 20 NAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHF 79
N D GAQIRA+ HLATVV IRGEID NV++IS+H+ RF+LG NP+VLD++++ F
Sbjct 12 NCVFDCEGAQIRAHHRHLATVVHIRGEIDDDNVDRISDHIARFTLGENPVVLDVADVDEF 71
Query 80 SGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDL 139
+ AGISLL D DCRAAGV W LVAS AV + L D H++ FP+ RSVH+AL D
Sbjct 72 AEAGISLLYAFDADCRAAGVDWTLVASSAVTQVL----DDTGHDASFPIMRSVHEALQDR 127
Query 140 ADAIDRRRQLVLPLISRS 157
ADAI RR++ LPL+ ++
Sbjct 128 ADAIALRRRMALPLVRKT 145
>gi|296168174|ref|ZP_06850195.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896852|gb|EFG76481.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=143
Score = 149 bits (376), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 79/145 (55%), Positives = 97/145 (67%), Gaps = 8/145 (5%)
Query 13 SVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLD 72
V TR N GGA +RA+ LATVVTIRGEIDA N +Q+ +H+RRF LG + +VLD
Sbjct 7 EVLTREQNGVFRCGGAWVRAHRRQLATVVTIRGEIDAVNADQVGDHIRRFILGEDRVVLD 66
Query 73 LSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSV 132
+S++S F+ AGISLL D +CRA GVQW LVA PAV E L ++ F SV
Sbjct 67 MSDVSQFAAAGISLLQTFDAECRAEGVQWTLVAGPAVAETL--------DDTGFSDNHSV 118
Query 133 HKALHDLADAIDRRRQLVLPLISRS 157
+ALHDLADAIDRRR+L LPL+ S
Sbjct 119 PEALHDLADAIDRRRRLALPLVRMS 143
>gi|145220947|ref|YP_001131625.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|315442083|ref|YP_004074962.1| STAS domain-containing protein [Mycobacterium sp. Spyr1]
gi|145213433|gb|ABP42837.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|315260386|gb|ADT97127.1| STAS domain-containing protein [Mycobacterium sp. Spyr1]
Length=135
Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 64/140 (46%), Positives = 86/140 (62%), Gaps = 7/140 (5%)
Query 19 GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH 78
GN GA IRA+ LATVV + G +D ANVE+ ++ RF L P VLDLSE+
Sbjct 3 GNPTFHCAGADIRAHCRQLATVVKVAGRLDNANVERAGRYIDRFILPEKPFVLDLSEVDS 62
Query 79 FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD 138
F ISLL ++D+ C AAG +W+L+AS AV + L D G FP A SV +AL+
Sbjct 63 FGEEAISLLFVIDDLCTAAGEEWSLIASRAVEQTLR---DSGIE---FPAAGSVPEALNH 116
Query 139 LADAIDRRRQLVLPLISRSA 158
ADA+ RR+L LPL++++A
Sbjct 117 FADAMVARRRL-LPLLTKTA 135
>gi|120401420|ref|YP_951249.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
gi|119954238|gb|ABM11243.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
Length=135
Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 66/140 (48%), Positives = 85/140 (61%), Gaps = 7/140 (5%)
Query 19 GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH 78
GN GA IRA+ LATVVTI G +D NVE S +V RF L P VLDLS +
Sbjct 3 GNPTFHCDGADIRAHCRQLATVVTISGHLDDVNVETASHYVDRFILTEKPFVLDLSGVDS 62
Query 79 FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD 138
F+ ISLL +D+ C +AGV W+++AS AV + L D G FP A SV +AL+
Sbjct 63 FTREAISLLFAIDDVCASAGVDWSMIASRAVEQTLR---DAGIE---FPAAGSVPEALNH 116
Query 139 LADAIDRRRQLVLPLISRSA 158
ADA+ RRQL LPL++++A
Sbjct 117 FADAMVTRRQL-LPLLTKTA 135
>gi|118469263|ref|YP_884997.1| STAS domain-containing protein [Mycobacterium smegmatis str.
MC2 155]
gi|118170550|gb|ABK71446.1| stas domain, putative [Mycobacterium smegmatis str. MC2 155]
Length=129
Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 54/132 (41%), Positives = 80/132 (61%), Gaps = 7/132 (5%)
Query 27 GAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISL 86
GA +RA+ LATVVT++G I + N++QIS +VRR + +VLDLS ++ F+ +SL
Sbjct 5 GASMRAHHRQLATVVTVKGAIGSENLDQISAYVRRLVIPEKSIVLDLSGVNSFAPQAVSL 64
Query 87 LCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR 146
+D C GV WA+VAS AV+ +L + ++ P+ SV ALH A+ R
Sbjct 65 FYAIDARCGELGVDWAVVASGAVLAEL------DDDDAGVPLTASVPDALHHFAEGTMAR 118
Query 147 RQLVLPLISRSA 158
R+L LPL+ +SA
Sbjct 119 RRL-LPLLVKSA 129
>gi|108797339|ref|YP_637536.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119866424|ref|YP_936376.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126432961|ref|YP_001068652.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
gi|108767758|gb|ABG06480.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119692513|gb|ABL89586.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126232761|gb|ABN96161.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
Length=151
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 47/125 (38%), Positives = 73/125 (59%), Gaps = 4/125 (3%)
Query 19 GNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSH 78
GN + D ++RA LATVVT+ G+IDA N+ ++++ RRF L P +LDLS +S
Sbjct 17 GNPSFDCDRVRMRARCRQLATVVTVTGDIDADNLSCVADYARRFVLAEKPFILDLSGVST 76
Query 79 FSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHD 138
F+ G+SL +D C A V+W+++ S V++ L G + M P+ SV +ALH
Sbjct 77 FAAEGLSLFYEIDARCAEADVEWSVIGSQPVLQVLRA---SGTLDDM-PVTASVPEALHH 132
Query 139 LADAI 143
++ I
Sbjct 133 FSEGI 137
>gi|240169577|ref|ZP_04748236.1| stas domain-containing protein [Mycobacterium kansasii ATCC 12478]
Length=147
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 49/134 (37%), Positives = 75/134 (56%), Gaps = 5/134 (3%)
Query 23 VDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGA 82
VD GA++ Y LAT+V I GEIDA+N E+I+ +RRF+ P++LDLS L S
Sbjct 2 VDCAGARLCVYARSLATIVRIDGEIDASNAERIAHEIRRFARVKAPLILDLSHLDFLSVD 61
Query 83 GISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADA 142
G L +L+ + AG+ +++A PA+ L + G P+A S+ +AL + D
Sbjct 62 GFRALLVLNHEHHKAGLHCSVIAGPAIRPLLRIVINHG-----LPVADSIAEALQLVEDV 116
Query 143 IDRRRQLVLPLISR 156
I RRQ + L+ +
Sbjct 117 ISSRRQFLAGLVKQ 130
>gi|296169161|ref|ZP_06850816.1| stas domain protein [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295896177|gb|EFG75842.1| stas domain protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=136
Score = 70.9 bits (172), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 45/114 (40%), Positives = 65/114 (58%), Gaps = 5/114 (4%)
Query 37 LATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA 96
+ATV+ I GE+DAAN + ++E +RRFS P+VLDL L +G+G+ L +LDE+ R
Sbjct 6 VATVLRIDGEVDAANTDLVAEAIRRFSRLKAPLVLDLGGLDFLAGSGLRALLVLDEEHRR 65
Query 97 AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
AG++ +V A+ D G P+A SV AL + A RR+LV
Sbjct 66 AGLRCCVVGGAALRRLTRVVPDHG-----LPIADSVASALAHIEGATTARRRLV 114
>gi|118464299|ref|YP_883045.1| stas domain-containing protein [Mycobacterium avium 104]
gi|118165586|gb|ABK66483.1| stas domain protein [Mycobacterium avium 104]
gi|336459154|gb|EGO38101.1| STAS domain-containing protein [Mycobacterium avium subsp. paratuberculosis
S397]
Length=143
Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/127 (30%), Positives = 65/127 (52%), Gaps = 5/127 (3%)
Query 24 DYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAG 83
D+ A + Y L TV+ + GE+DA+N ++ +RRF P+VLDLS L S G
Sbjct 3 DFARAHLFVYARSLGTVLRVDGEVDASNARDLTATIRRFGRLKTPLVLDLSRLRFISVEG 62
Query 84 ISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI 143
L +L+++ R + V +V A+ L + H++ +A SV +A ++ D +
Sbjct 63 FRALLLLNDELRKSRVHCCVVPGAAIRALL-----RLVHDNGLALADSVPEAFQNIEDIV 117
Query 144 DRRRQLV 150
RR+ +
Sbjct 118 RARREFL 124
>gi|254776304|ref|ZP_05217820.1| hypothetical protein MaviaA2_16772 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=163
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/127 (30%), Positives = 65/127 (52%), Gaps = 5/127 (3%)
Query 24 DYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAG 83
D+ A + Y L TV+ + GE+DA+N ++ +RRF P+VLDLS L S G
Sbjct 23 DFARAHLFVYARSLGTVLRVDGEVDASNARDLTATIRRFGRLKTPLVLDLSRLRFISVEG 82
Query 84 ISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI 143
L +L+++ R + V +V A+ L + H++ +A SV +A ++ D +
Sbjct 83 FRALLLLNDELRKSRVHCCVVPGAAIRALL-----RLVHDNGLALADSVPEAFQNIEDIV 137
Query 144 DRRRQLV 150
RR+ +
Sbjct 138 RARREFL 144
>gi|342858142|ref|ZP_08714797.1| stas domain-containing protein [Mycobacterium colombiense CECT
3035]
gi|342133846|gb|EGT87026.1| stas domain-containing protein [Mycobacterium colombiense CECT
3035]
Length=143
Score = 64.7 bits (156), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 41/126 (33%), Positives = 65/126 (52%), Gaps = 5/126 (3%)
Query 25 YGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGI 84
+G A + Y +L TV+ + GE+DA N ++ +R F+ P+VLDLS L S G
Sbjct 4 FGRAHLFVYARNLGTVLRVDGEVDACNANDLTGAIRNFARLKTPLVLDLSHLRFVSVEGF 63
Query 85 SLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAID 144
L +L+++ R A V ++V AV L + H + +A SV +A +L D +
Sbjct 64 RALLLLNDEFRKARVYCSVVGGAAVRPLL-----RIVHHNGLSIAGSVPEAFQNLEDVLW 118
Query 145 RRRQLV 150
RRQ +
Sbjct 119 ARRQFL 124
>gi|254821742|ref|ZP_05226743.1| stas domain-containing protein [Mycobacterium intracellulare
ATCC 13950]
Length=143
Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 41/126 (33%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
Query 25 YGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGI 84
+ A + Y LATVV + GEIDAAN ++E +R F+ P+VLDLS L S G
Sbjct 4 FARAHVFVYARCLATVVRVDGEIDAANARDLTEAIRGFARLKTPVVLDLSRLRFLSVEGF 63
Query 85 SLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAID 144
L ++++ R A V ++V A+ L + H++ SV +A + D +
Sbjct 64 RALLFVNDELRKARVHCSVVTGKAIRPLL-----RIVHDNGLATTDSVPEAFQTIEDILA 118
Query 145 RRRQLV 150
RR+ V
Sbjct 119 ARRRFV 124
>gi|296169142|ref|ZP_06850798.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896191|gb|EFG75855.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=135
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 67/130 (52%), Gaps = 17/130 (13%)
Query 23 VDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGA 82
+D GAQ+ H LATV+ I+GE+DA+N + +++ +RRF P++LDL + + A
Sbjct 17 IDCAGAQLDVQAHALATVLRIQGELDASNADLVAQAIRRFVRLRAPLILDLRRVEYLGSA 76
Query 83 GISLLCILDEDCRAAGVQWALVASPA------VVEQLGGRCDQGEHESMFPMARSVHKAL 136
G+ L ++ E+C+ + ++V A +V LG P+ SV +AL
Sbjct 77 GLRALLLVQEECQLVRLHCSVVGGVALRRLTRLVTGLG-----------LPLVDSVSEAL 125
Query 137 HDLADAIDRR 146
+ + RR
Sbjct 126 QLIQGSKQRR 135
>gi|41409166|ref|NP_962002.1| hypothetical protein MAP3068 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41397986|gb|AAS05616.1| hypothetical protein MAP_3068 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=163
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 37/127 (30%), Positives = 64/127 (51%), Gaps = 5/127 (3%)
Query 24 DYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAG 83
D+ A + Y L TV+ + GE+DA+N ++ +RRF P+VLDLS L S
Sbjct 23 DFARAHLFVYARSLGTVLRVDGEVDASNARDLTATIRRFGRLKTPLVLDLSRLRFISVES 82
Query 84 ISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAI 143
L +L+++ R + V +V A+ L + H++ +A SV +A ++ D +
Sbjct 83 FRALLLLNDELRKSRVHCCVVPGAAIRALL-----RLVHDNGLALADSVPEAFQNIEDIV 137
Query 144 DRRRQLV 150
RR+ +
Sbjct 138 RARREFL 144
>gi|108797874|ref|YP_638071.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119866968|ref|YP_936920.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126433514|ref|YP_001069205.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
gi|108768293|gb|ABG07015.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119693057|gb|ABL90130.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126233314|gb|ABN96714.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
Length=106
Score = 60.1 bits (144), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 44/82 (54%), Gaps = 0/82 (0%)
Query 33 YLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDE 92
+L +T+ G +DA N + E+V R + + LDL+ + S AG S+LC + E
Sbjct 13 WLAPFEVRITVAGSVDATNAADLEEYVLRRGANSRRLTLDLTGVDFLSTAGFSVLCTIGE 72
Query 93 DCRAAGVQWALVASPAVVEQLG 114
C A V+W LVA+P V LG
Sbjct 73 RCVRADVEWTLVANPTVRRVLG 94
>gi|342861500|ref|ZP_08718147.1| hypothetical protein MCOL_21546 [Mycobacterium colombiense CECT
3035]
gi|342130989|gb|EGT84278.1| hypothetical protein MCOL_21546 [Mycobacterium colombiense CECT
3035]
Length=138
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 31/86 (37%), Positives = 47/86 (55%), Gaps = 0/86 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q+ +V++ + + ++LDL L AG S L
Sbjct 13 AQFTARWGPTGTLITVDGELDAANADQLVAYVQQSTSRSRRVILDLRGLKFIGTAGFSAL 72
Query 88 CILDEDCRAAGVQWALVASPAVVEQL 113
++ C A V WA+ SPAV L
Sbjct 73 HRINVKCSGAQVSWAMAPSPAVARLL 98
>gi|254819524|ref|ZP_05224525.1| hypothetical protein MintA_06344 [Mycobacterium intracellulare
ATCC 13950]
Length=138
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 31/82 (38%), Positives = 47/82 (58%), Gaps = 0/82 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q++ +V++ + ++LDL L AG S L
Sbjct 11 AQFTARWGPTGTLITVDGELDAANADQLAAYVQQSVNRSRRVILDLRGLKFIGTAGFSTL 70
Query 88 CILDEDCRAAGVQWALVASPAV 109
++ C AA V WA+ SPAV
Sbjct 71 HRINVVCSAAQVSWAMAPSPAV 92
>gi|145224460|ref|YP_001135138.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|145216946|gb|ABP46350.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
Length=155
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/114 (35%), Positives = 56/114 (50%), Gaps = 8/114 (7%)
Query 41 VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQ 100
V + GE+DA N +++ +V R + +VLDL + F G + L + C + V
Sbjct 40 VAVVGEVDAVNGRELARYVERHLRVSRQLVLDLRAVDFFGSQGFTALYYISVHCTRSDVD 99
Query 101 WALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLVLPLI 154
WA+VASP V +L CD ES P+A + AL L DRR Q P +
Sbjct 100 WAIVASPP-VRRLLSICDP---ESELPLADDLTAALARL----DRRAQRHTPFV 145
>gi|315444795|ref|YP_004077674.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
gi|315263098|gb|ADT99839.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
Length=155
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/114 (35%), Positives = 56/114 (50%), Gaps = 8/114 (7%)
Query 41 VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQ 100
V + GE+DA N +++ +V R + +VLDL + F G + L + C + V
Sbjct 40 VAVVGEVDAVNGRELARYVERHLRVSRQLVLDLRAVDFFGSQGFTALYYISVHCTRSDVD 99
Query 101 WALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLVLPLI 154
WA+VASP V +L CD ES P+A + AL L DRR Q P +
Sbjct 100 WAIVASPP-VRRLLSICDP---ESELPLADDLTAALARL----DRRAQRHTPFV 145
>gi|118464650|ref|YP_883397.1| STAS domain-containing protein [Mycobacterium avium 104]
gi|118165937|gb|ABK66834.1| stas domain, putative [Mycobacterium avium 104]
Length=140
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/86 (37%), Positives = 48/86 (56%), Gaps = 0/86 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q++ +V++ + ++LDL L+ AG S L
Sbjct 13 AQFTARWGLTGTLITVDGELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSAL 72
Query 88 CILDEDCRAAGVQWALVASPAVVEQL 113
++ C AA WA+ SPAV L
Sbjct 73 HRINVICSAAQTSWAMAPSPAVARLL 98
>gi|254776691|ref|ZP_05218207.1| hypothetical protein MaviaA2_18771 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=138
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/86 (37%), Positives = 48/86 (56%), Gaps = 0/86 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q++ +V++ + ++LDL L+ AG S L
Sbjct 11 AQFTARWGLTGTLITVDGELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSAL 70
Query 88 CILDEDCRAAGVQWALVASPAVVEQL 113
++ C AA WA+ SPAV L
Sbjct 71 HRINVICSAAQTSWAMAPSPAVARLL 96
>gi|41409503|ref|NP_962339.1| hypothetical protein MAP3405 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398334|gb|AAS05955.1| Rv0516c [Mycobacterium avium subsp. paratuberculosis K-10]
Length=144
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/86 (37%), Positives = 48/86 (56%), Gaps = 0/86 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q++ +V++ + ++LDL L+ AG S L
Sbjct 17 AQFTARWGLTGTLITVDGELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSAL 76
Query 88 CILDEDCRAAGVQWALVASPAVVEQL 113
++ C AA WA+ SPAV L
Sbjct 77 HRINVICSAAQTSWAMAPSPAVARLL 102
>gi|336459632|gb|EGO38567.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium avium subsp. paratuberculosis S397]
Length=140
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/86 (37%), Positives = 48/86 (56%), Gaps = 0/86 (0%)
Query 28 AQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLL 87
AQ A T++T+ GE+DAAN +Q++ +V++ + ++LDL L+ AG S L
Sbjct 13 AQFTARWGLTGTLITVDGELDAANADQLAAYVQQSVNRSRRVILDLRGLNFIGTAGFSAL 72
Query 88 CILDEDCRAAGVQWALVASPAVVEQL 113
++ C AA WA+ SPAV L
Sbjct 73 HRINVICSAAQTSWAMAPSPAVARLL 98
>gi|296168914|ref|ZP_06850583.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896383|gb|EFG76036.1| anti-sigma-factor antagonist [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=142
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/112 (34%), Positives = 54/112 (49%), Gaps = 2/112 (1%)
Query 27 GAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISL 86
AQ A T++T+ GE+DAAN +Q++ +VR + ++LDL L AG S
Sbjct 16 AAQFTARWDPSGTLITVDGELDAANADQLAAYVRHVVDRSRRVILDLRGLKFIGTAGFSA 75
Query 87 LCILDEDCRAAGVQWALVASPAVVEQLGGRCD-QGEHESMFPMARSVHKALH 137
L ++ C A WA+ SPAV L CD G PMA + + L
Sbjct 76 LHRINVVCSGAQAHWAMAPSPAVARLL-RICDPDGTLPVTTPMAEPLLEPLR 126
>gi|240171603|ref|ZP_04750262.1| hypothetical protein MkanA1_19973 [Mycobacterium kansasii ATCC
12478]
Length=132
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/84 (39%), Positives = 46/84 (55%), Gaps = 0/84 (0%)
Query 26 GGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGIS 85
G A A A V+T+ GE+DAAN +Q++ +V++ + LDL L AG S
Sbjct 9 GTADFTASYGPSAGVITVEGELDAANADQLTGYVQQCVRSCRWLTLDLRHLEFIGTAGFS 68
Query 86 LLCILDEDCRAAGVQWALVASPAV 109
L ++ C AA ++WALV S AV
Sbjct 69 ALHRINVVCSAADIRWALVPSRAV 92
>gi|315445713|ref|YP_004078592.1| STAS domain-containing protein [Mycobacterium sp. Spyr1]
gi|315264016|gb|ADU00758.1| STAS domain-containing protein [Mycobacterium sp. Spyr1]
Length=144
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 38/111 (35%), Positives = 58/111 (53%), Gaps = 4/111 (3%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+V +GE+DAAN + ++ R + T +V+DLS LS FS AG S L L+ C +
Sbjct 34 IVAGKGEVDAANGIRFVDYALRHAEQTQWLVIDLSGLSFFSTAGFSALHTLNVQCVGEDI 93
Query 100 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
+WALV A V ++ CD +S P+ V AL + + R +L+
Sbjct 94 RWALVPGTA-VHRVLRICDP---DSALPICPDVPAALVAVQEDPPRSFELI 140
>gi|145225366|ref|YP_001136044.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|145217852|gb|ABP47256.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
Length=144
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 38/111 (35%), Positives = 58/111 (53%), Gaps = 4/111 (3%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+V +GE+DAAN + ++ R + T +V+DLS LS FS AG S L L+ C +
Sbjct 34 IVAGKGEVDAANGIRFVDYALRHADQTQWLVIDLSGLSFFSTAGFSALHTLNVQCVGEDI 93
Query 100 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
+WALV A V ++ CD +S P+ V AL + + R +L+
Sbjct 94 RWALVPGTA-VHRVLRICDP---DSALPICPDVPSALVAVQEDPPRSFELI 140
>gi|126433913|ref|YP_001069604.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
gi|126233713|gb|ABN97113.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
Length=141
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 39/112 (35%), Positives = 55/112 (50%), Gaps = 6/112 (5%)
Query 39 TVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAG 98
TVVT+ GE+DAAN ++ + G +++DL+ + F AG S L L+ C A
Sbjct 32 TVVTVTGELDAANARDFADFALLHAGGA--LIVDLAGVEFFGTAGFSALHTLNVRCAGAD 89
Query 99 VQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
+ W LV S A V +L CD ++ P + SV AL L QLV
Sbjct 90 INWILVPS-AAVSRLLRICDP---DATLPWSESVETALTALQGEPRPLLQLV 137
>gi|120405652|ref|YP_955481.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
gi|119958470|gb|ABM15475.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
Length=135
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/73 (37%), Positives = 41/73 (57%), Gaps = 0/73 (0%)
Query 41 VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQ 100
V++ GE+DAAN + + VR + G ++LDLSE++ + G S L + GV
Sbjct 40 VSVWGEVDAANAKHFAHTVREVAEGNAALILDLSEVNFMAFDGASALYAISAQLAREGVT 99
Query 101 WALVASPAVVEQL 113
W ++ASPAV L
Sbjct 100 WCVIASPAVSRVL 112
>gi|108798253|ref|YP_638450.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119867349|ref|YP_937301.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|108768672|gb|ABG07394.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119693438|gb|ABL90511.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
Length=141
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 39/112 (35%), Positives = 55/112 (50%), Gaps = 6/112 (5%)
Query 39 TVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAG 98
TVVT+ GE+DAAN ++ + G +++DL+ + F AG S L L+ C A
Sbjct 32 TVVTVAGELDAANARDFADFALLHAGGA--LIVDLAGVEFFGTAGFSALHTLNVRCAGAD 89
Query 99 VQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
+ W LV S A V +L CD ++ P + SV AL L QLV
Sbjct 90 INWILVPS-AAVSRLLRICDP---DATLPWSESVDTALTALQGEPRPLLQLV 137
>gi|145222611|ref|YP_001133289.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|145215097|gb|ABP44501.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
Length=135
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/88 (35%), Positives = 47/88 (54%), Gaps = 4/88 (4%)
Query 41 VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQ 100
V++RGE+DA N + + VR + G+ +VLDL+E+S + G S L + V
Sbjct 40 VSVRGEVDALNAKHFAHTVREMAGGSAALVLDLTEVSFLAFDGASALYAISAHLAREDVT 99
Query 101 WALVASPAVVEQLGGRCDQGEHESMFPM 128
W +V SPA V ++ CD E + P+
Sbjct 100 WCVVPSPA-VSRVVKLCDP---EGLIPL 123
>gi|120402667|ref|YP_952496.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
gi|119955485|gb|ABM12490.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
Length=147
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 40/111 (37%), Positives = 56/111 (51%), Gaps = 4/111 (3%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+V+ GE+DAAN + R S + +V+DLS L+ FS AG S L L+ C + +
Sbjct 37 IVSGLGELDAANGIDFVGYALRHSDRAHWLVVDLSGLTFFSTAGFSALHTLNVQCVSEDI 96
Query 100 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRRRQLV 150
+WALV S A V++L CD + P V AL + R QLV
Sbjct 97 RWALVPSKA-VDRLLRICDP---DHALPTCADVPTALTVVQQEPPRSLQLV 143
>gi|315443076|ref|YP_004075955.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
gi|315261379|gb|ADT98120.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
Length=135
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/88 (35%), Positives = 46/88 (53%), Gaps = 4/88 (4%)
Query 41 VTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQ 100
V++RGE+DA N + VR + G+ +VLDL+E+S + G S L + V
Sbjct 40 VSVRGEVDALNARHFAHTVREMAGGSAALVLDLTEVSFLAFDGASALYAISAHLAREDVT 99
Query 101 WALVASPAVVEQLGGRCDQGEHESMFPM 128
W +V SPA V ++ CD E + P+
Sbjct 100 WCVVPSPA-VSRVVKLCDP---EGLIPL 123
>gi|333991689|ref|YP_004524303.1| anti-sigma-factor antagonist [Mycobacterium sp. JDM601]
gi|333487657|gb|AEF37049.1| anti-sigma-factor antagonist [Mycobacterium sp. JDM601]
Length=107
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+V GEIDAAN +++ RR + ++LDL+EL+ G + L + C AA
Sbjct 1 MVAADGEIDAANAAPFADYARRCADCCEWLILDLAELAFIGTVGFTALQSVSARCAAAQT 60
Query 100 QWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDL 139
+ +V SPAV L CD +S P+ S+ AL D+
Sbjct 61 RLMVVPSPAVTSVL-RICD---PQSRLPLVPSLADALADV 96
>gi|169629598|ref|YP_001703247.1| hypothetical protein MAB_2512 [Mycobacterium abscessus ATCC 19977]
gi|169241565|emb|CAM62593.1| Conserved hypothetical protein (sulfate transporter/antisigma-factor
antagonist STAS?) [Mycobacterium abscessus]
Length=140
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 28/87 (33%), Positives = 43/87 (50%), Gaps = 1/87 (1%)
Query 28 AQIRAYLHH-LATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISL 86
A+ A+ H A +V GEIDA N ++E+ R+ G +VLDL L F G+
Sbjct 30 ARFTAHWHRPSAVLVRATGEIDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVA 89
Query 87 LCILDEDCRAAGVQWALVASPAVVEQL 113
L + C+ G+ W ++ AV + L
Sbjct 90 LDRVRRHCKVQGIDWTVIPGDAVTKLL 116
>gi|108799864|ref|YP_640061.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119868974|ref|YP_938926.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126435507|ref|YP_001071198.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
gi|108770283|gb|ABG09005.1| anti-sigma-factor antagonist [Mycobacterium sp. MCS]
gi|119695063|gb|ABL92136.1| anti-sigma-factor antagonist [Mycobacterium sp. KMS]
gi|126235307|gb|ABN98707.1| anti-sigma-factor antagonist [Mycobacterium sp. JLS]
Length=148
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 38/111 (35%), Positives = 53/111 (48%), Gaps = 7/111 (6%)
Query 39 TVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAG 98
+VVT GEIDA N + +V + +++DL+ ++ F G S L + C
Sbjct 38 SVVTAVGEIDATNGRDLGRYVECHTASATQLIVDLTGVTFFGSQGFSALHYMSVSCTRID 97
Query 99 VQWALVASPAVVEQLGGRCD-QGEHESMFPMARSVHKALHDLADAIDRRRQ 148
V W +V V +L CD QGE P+A SV A L D + RRRQ
Sbjct 98 VDWVIVPG-GEVRRLLRICDPQGE----LPLADSVDAACARL-DRVTRRRQ 142
>gi|120403518|ref|YP_953347.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
gi|119956336|gb|ABM13341.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
Length=155
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 34/109 (32%), Positives = 50/109 (46%), Gaps = 6/109 (5%)
Query 31 RAYLHHLATVVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCIL 90
R H +A V GEIDA N + +V R + + +VLDL + F G + L +
Sbjct 32 RCSAHRMAIAVI--GEIDAVNGRALGRYVERHTRISRQLVLDLRAVDFFGSQGFTALYYI 89
Query 91 DEDCRAAGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDL 139
C + V W +V SPA V +L CD + P+ ++ AL L
Sbjct 90 SVHCARSDVDWVIVGSPA-VRRLLAICDP---DGELPLTDALSSALARL 134
>gi|145220808|ref|YP_001131486.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|315442239|ref|YP_004075118.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
gi|145213294|gb|ABP42698.1| anti-sigma-factor antagonist [Mycobacterium gilvum PYR-GCK]
gi|315260542|gb|ADT97283.1| anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
[Mycobacterium sp. Spyr1]
Length=152
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/79 (32%), Positives = 44/79 (56%), Gaps = 1/79 (1%)
Query 40 VVTIRGEIDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGV 99
+VTI GEIDA N ++ ++ + + +++DL + F+ +G + L ++ C GV
Sbjct 45 LVTIHGEIDATNNMPLAHYIEKRIGDSRKLIVDLQTVEFFAASGFAALFNVNVVCHRRGV 104
Query 100 QWALVASPAVVEQLGGRCD 118
+W L+A P V +L CD
Sbjct 105 RWQLLAGPH-VRRLLRVCD 122
>gi|120401717|ref|YP_951546.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
gi|119954535|gb|ABM11540.1| anti-sigma-factor antagonist [Mycobacterium vanbaalenii PYR-1]
Length=152
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/110 (28%), Positives = 52/110 (48%), Gaps = 5/110 (4%)
Query 1 MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAY-----LHHLATVVTIRGEIDAANVEQI 55
M+ T P S+ RP + + RA L +VTI GE+DA N +
Sbjct 1 MSITDPLPASSTQRVFRPDPTSFELREEHHRATFSACELPPSTVLVTIHGEVDATNSMAL 60
Query 56 SEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVA 105
+ ++ + G ++LDL + F+ +G + L ++ C +GV+W L+A
Sbjct 61 ACYIEKRLGGARKLILDLQTVEFFAASGFAALSNINVVCARSGVRWTLLA 110
>gi|148270482|ref|YP_001244942.1| anti-sigma-factor antagonist [Thermotoga petrophila RKU-1]
gi|147736026|gb|ABQ47366.1| anti-sigma-factor antagonist [Thermotoga petrophila RKU-1]
Length=110
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 22/66 (34%), Positives = 39/66 (60%), Gaps = 2/66 (3%)
Query 40 VVTIRGEIDAANVEQISEHVRRF--SLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAA 97
+V ++GEIDA N ++ E +R F + +VLDLS +S+ AG+ L ++ +D +
Sbjct 16 IVRVQGEIDAYNSSELKEQLRSFISTTSKKKIVLDLSSVSYMDSAGLGTLVVILKDAKIN 75
Query 98 GVQWAL 103
G ++ L
Sbjct 76 GKEFIL 81
Lambda K H
0.320 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 128907826664
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40