BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0536

Length=346
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15839932|ref|NP_334969.1|  NAD-dependent epimerase/dehydratase...   688    0.0   
gi|289744248|ref|ZP_06503626.1|  UDP-glucose 4-epimerase galE3 [M...   688    0.0   
gi|289441922|ref|ZP_06431666.1|  UDP-glucose 4-epimerase galE3 [M...   686    0.0   
gi|339293583|gb|AEJ45694.1|  UDP-glucose 4-epimerase galE3 [Mycob...   683    0.0   
gi|253797468|ref|YP_003030469.1|  UDP-glucose 4-epimerase galE3 [...   659    0.0   
gi|289756614|ref|ZP_06515992.1|  UDP-glucose 4-epimerase galE3 [M...   652    0.0   
gi|307083028|ref|ZP_07492141.1|  NAD dependent epimerase/dehydrat...   650    0.0   
gi|296168247|ref|ZP_06850220.1|  possible UDP-glucose 4-epimerase...   590    1e-166
gi|183980903|ref|YP_001849194.1|  UDP-glucose 4-epimerase, GalE3 ...   589    2e-166
gi|298524019|ref|ZP_07011428.1|  UDP-glucose 4-epimerase [Mycobac...   589    2e-166
gi|118616439|ref|YP_904771.1|  UDP-glucose 4-epimerase, GalE3 [My...   587    1e-165
gi|342858955|ref|ZP_08715609.1|  putative UDP-glucose 4-epimerase...   568    6e-160
gi|240171284|ref|ZP_04749943.1|  UDP-glucose 4-epimerase, GalE3 [...   555    3e-156
gi|254777045|ref|ZP_05218561.1|  NAD-dependent epimerase/dehydrat...   552    3e-155
gi|254818932|ref|ZP_05223933.1|  NAD-dependent epimerase/dehydrat...   551    5e-155
gi|118466473|ref|YP_883738.1|  NAD-dependent epimerase/dehydratas...   546    2e-153
gi|289749034|ref|ZP_06508412.1|  UDP-glucose 4-epimerase galE3 [M...   535    3e-150
gi|108797684|ref|YP_637881.1|  NAD-dependent epimerase/dehydratas...   509    3e-142
gi|126433309|ref|YP_001069000.1|  NAD-dependent epimerase/dehydra...   508    5e-142
gi|118469353|ref|YP_885393.1|  NAD-dependent epimerase/dehydratas...   490    2e-136
gi|254230879|ref|ZP_04924206.1|  UDP-glucose 4-epimerase galE3 [M...   486    2e-135
gi|120401897|ref|YP_951726.1|  NAD-dependent epimerase/dehydratas...   457    1e-126
gi|226363583|ref|YP_002781365.1|  nucleotide-sugar epimerase [Rho...   395    5e-108
gi|111021237|ref|YP_704209.1|  UDP-glucose 4-epimerase [Rhodococc...   384    1e-104
gi|320012487|gb|ADW07337.1|  NAD-dependent epimerase/dehydratase ...   380    2e-103
gi|325000783|ref|ZP_08121895.1|  UDP-glucose 4-epimerase [Pseudon...   369    3e-100
gi|182440498|ref|YP_001828217.1|  putative UDP-glucose 4-epimeras...   368    8e-100
gi|326781168|ref|ZP_08240433.1|  UDP-glucose 4-epimerase [Strepto...   367    2e-99 
gi|300790126|ref|YP_003770417.1|  UDP-glucose 4-epimerase [Amycol...   361    8e-98 
gi|302530361|ref|ZP_07282703.1|  UDP-glucose 4-epimerase [Strepto...   358    5e-97 
gi|290955581|ref|YP_003486763.1|  epimerase/dehydratase [Streptom...   358    6e-97 
gi|302868412|ref|YP_003837049.1|  NAD-dependent epimerase/dehydra...   357    2e-96 
gi|291453182|ref|ZP_06592572.1|  epimerase [Streptomyces albus J1...   354    1e-95 
gi|306416865|gb|ADM87279.1|  putative UDP-glucose 4-epimerase [St...   352    4e-95 
gi|134099884|ref|YP_001105545.1|  UDP-glucose 4-epimerase [Saccha...   352    7e-95 
gi|302538232|ref|ZP_07290574.1|  epimerase [Streptomyces sp. C] >...   351    9e-95 
gi|331699676|ref|YP_004335915.1|  UDP-glucose 4-epimerase [Pseudo...   351    1e-94 
gi|86739689|ref|YP_480089.1|  NAD-dependent epimerase/dehydratase...   348    8e-94 
gi|159038332|ref|YP_001537585.1|  NAD-dependent epimerase/dehydra...   347    1e-93 
gi|345003429|ref|YP_004806283.1|  NAD-dependent epimerase/dehydra...   342    5e-92 
gi|311743371|ref|ZP_07717178.1|  NAD-dependent epimerase/dehydrat...   342    7e-92 
gi|291300413|ref|YP_003511691.1|  NAD-dependent epimerase/dehydra...   341    8e-92 
gi|345009975|ref|YP_004812329.1|  NAD-dependent epimerase/dehydra...   338    5e-91 
gi|289770655|ref|ZP_06530033.1|  epimerase [Streptomyces lividans...   337    2e-90 
gi|297560679|ref|YP_003679653.1|  NAD-dependent epimerase/dehydra...   337    2e-90 
gi|302554751|ref|ZP_07307093.1|  epimerase [Streptomyces viridoch...   336    4e-90 
gi|336176419|ref|YP_004581794.1|  UDP-glucose 4-epimerase [Franki...   336    4e-90 
gi|328886562|emb|CCA59801.1|  NAD-dependent epimerase or dehydrat...   335    6e-90 
gi|21222151|ref|NP_627930.1|  epimerase [Streptomyces coelicolor ...   334    1e-89 
gi|329937260|ref|ZP_08286859.1|  epimerase [Streptomyces griseoau...   330    1e-88 


>gi|15839932|ref|NP_334969.1| NAD-dependent epimerase/dehydratase family protein [Mycobacterium 
tuberculosis CDC1551]
 gi|31791718|ref|NP_854211.1| UDP-glucose 4-epimerase [Mycobacterium bovis AF2122/97]
 gi|57116753|ref|YP_177737.1| UDP-glucose 4-epimerase [Mycobacterium tuberculosis H37Rv]
 56 more sequence titles
 Length=346

 Score =  688 bits (1776),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 346/346 (100%), Positives = 346/346 (100%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
Sbjct  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346


>gi|289744248|ref|ZP_06503626.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis 02_1987]
 gi|294996046|ref|ZP_06801737.1| putative UDP-glucose 4-epimerase [Mycobacterium tuberculosis 
210]
 gi|289684776|gb|EFD52264.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis 02_1987]
 gi|326902365|gb|EGE49298.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis W-148]
Length=346

 Score =  688 bits (1775),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 345/346 (99%), Positives = 346/346 (100%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAG+NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGINAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
Sbjct  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346


>gi|289441922|ref|ZP_06431666.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T46]
 gi|289414841|gb|EFD12081.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T46]
Length=346

 Score =  686 bits (1771),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 345/346 (99%), Positives = 345/346 (99%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALL AAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLAAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
Sbjct  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346


>gi|339293583|gb|AEJ45694.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis CCDC5079]
 gi|339297223|gb|AEJ49333.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis CCDC5180]
Length=344

 Score =  683 bits (1762),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 342/344 (99%), Positives = 344/344 (100%), Gaps = 0/344 (0%)

Query  3    VLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPL  62
            +LLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPL
Sbjct  1    MLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPL  60

Query  63   LAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQ  122
            LAGVDLVCHQAAMVGAG+NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQ
Sbjct  61   LAGVDLVCHQAAMVGAGINAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQ  120

Query  123  GRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTA  182
            GRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTA
Sbjct  121  GRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTA  180

Query  183  QEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQ  242
            QEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQ
Sbjct  181  QEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQ  240

Query  243  MRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAI  302
            MRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAI
Sbjct  241  MRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAI  300

Query  303  TGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            TGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  301  TGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  344


>gi|253797468|ref|YP_003030469.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis KZN 
1435]
 gi|253318971|gb|ACT23574.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis KZN 
1435]
Length=331

 Score =  659 bits (1701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 330/331 (99%), Positives = 331/331 (100%), Gaps = 0/331 (0%)

Query  16   VDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAM  75
            +DAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAM
Sbjct  1    MDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAM  60

Query  76   VGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDP  135
            VGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDP
Sbjct  61   VGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDP  120

Query  136  LPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASG  195
            LPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASG
Sbjct  121  LPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASG  180

Query  196  GSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQMRDFVHVDDVAAA  255
            GSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQMRDFVHVDDVAAA
Sbjct  181  GSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQMRDFVHVDDVAAA  240

Query  256  NLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIV  315
            NLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIV
Sbjct  241  NLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIV  300

Query  316  ADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            ADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  301  ADPARAARVLGFRAAVDPGEGLREFAFAPLR  331


>gi|289756614|ref|ZP_06515992.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T85]
 gi|289712178|gb|EFD76190.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T85]
Length=345

 Score =  652 bits (1683),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 326/327 (99%), Positives = 327/327 (100%), Gaps = 0/327 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
Sbjct  15   MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  74

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAG+NAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  75   PLLAGVDLVCHQAAMVGAGINAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  134

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  135  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  194

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  195  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  254

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
Sbjct  255  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  314

Query  301  AITGHYRSGDVRHIVADPARAARVLGF  327
            AITGHYRSGDVRHIVADPARAARVLGF
Sbjct  315  AITGHYRSGDVRHIVADPARAARVLGF  341


>gi|307083028|ref|ZP_07492141.1| NAD dependent epimerase/dehydratase family protein [Mycobacterium 
tuberculosis SUMu012]
 gi|308367253|gb|EFP56104.1| NAD dependent epimerase/dehydratase family protein [Mycobacterium 
tuberculosis SUMu012]
Length=338

 Score =  650 bits (1677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 326/326 (100%), Positives = 326/326 (100%), Gaps = 0/326 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP
Sbjct  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLG  326
            AITGHYRSGDVRHIVADPARAARVLG
Sbjct  301  AITGHYRSGDVRHIVADPARAARVLG  326


>gi|296168247|ref|ZP_06850220.1| possible UDP-glucose 4-epimerase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295896819|gb|EFG76450.1| possible UDP-glucose 4-epimerase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=343

 Score =  590 bits (1521),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 297/346 (86%), Positives = 318/346 (92%), Gaps = 3/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIG+RV AALRAAGHDV+GVDALLPAAHGPNPVLP GC RVDVRDA ALA
Sbjct  1    MRVLLTGAAGFIGTRVAAALRAAGHDVIGVDALLPAAHGPNPVLPQGCHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLL GVD+VCHQAAMVGAGV+AADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLDGVDVVCHQAAMVGAGVDAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRY C +HG VDP+PRRRADLD G+FEHRCP   E + W+LVDED  LRPRSLYAASK
Sbjct  121  GQGRYRCGRHGDVDPVPRRRADLDAGIFEHRCPVGDEELAWRLVDEDTALRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAW+EA GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS++E+G+PP+VFEDG
Sbjct  181  TAQEHYALAWAEADGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSSLERGEPPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAV    + RDGFTAVNVCSGRPISILQVA A+CDARGG+ SP
Sbjct  241  GQMRDFVHVDDVAAANLAAV---TSTRDGFTAVNVCSGRPISILQVAGALCDARGGAFSP  297

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADP+RAA VLGFRAAVDP +GLREFAFAPLR
Sbjct  298  VVTGQYRSGDVRHIVADPSRAAEVLGFRAAVDPADGLREFAFAPLR  343


>gi|183980903|ref|YP_001849194.1| UDP-glucose 4-epimerase, GalE3 [Mycobacterium marinum M]
 gi|183174229|gb|ACC39339.1| UDP-glucose 4-epimerase, GalE3 [Mycobacterium marinum M]
Length=346

 Score =  589 bits (1519),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 298/346 (87%), Positives = 319/346 (93%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            M+VLLTGAAGFIGSRV AAL AAGH+VVGVD LLPAAHGPNPVLPPGC RVDVRDA A+A
Sbjct  1    MKVLLTGAAGFIGSRVGAALSAAGHEVVGVDVLLPAAHGPNPVLPPGCHRVDVRDADAMA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCP+HG +DPLPRR +DLD GVFEHRCP C EPV W+LV E+A LRPRSLYAASK
Sbjct  121  GQGRYDCPEHGRIDPLPRRHSDLDAGVFEHRCPLCAEPVRWRLVGEEAELRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSE++GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS++EKG+PPKVFEDG
Sbjct  181  TAQEHYALAWSESTGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSSLEKGEPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDD+AAANLAA  LGE DR GF A NVCSGRPISILQVA+A+C ARG ++SP
Sbjct  241  GQMRDFVHVDDIAAANLAAAQLGEVDRHGFVAANVCSGRPISILQVASALCQARGDALSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             ITG YRSGDVRHIVADP+RAA VLGFRAAV+P EGLR FAFAPLR
Sbjct  301  VITGQYRSGDVRHIVADPSRAAEVLGFRAAVEPLEGLRGFAFAPLR  346


>gi|298524019|ref|ZP_07011428.1| UDP-glucose 4-epimerase [Mycobacterium tuberculosis 94_M4241A]
 gi|298493813|gb|EFI29107.1| UDP-glucose 4-epimerase [Mycobacterium tuberculosis 94_M4241A]
Length=294

 Score =  589 bits (1519),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 292/294 (99%), Positives = 294/294 (100%), Gaps = 0/294 (0%)

Query  53   VRDASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLV  112
            +RDASALAPLLAGVDLVCHQAAMVGAG+NAADAPAYGGHNDFATTVLLAQMFAAGVRRLV
Sbjct  1    MRDASALAPLLAGVDLVCHQAAMVGAGINAADAPAYGGHNDFATTVLLAQMFAAGVRRLV  60

Query  113  LASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRP  172
            LASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRP
Sbjct  61   LASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRP  120

Query  173  RSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGK  232
            RSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGK
Sbjct  121  RSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGK  180

Query  233  PPKVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICD  292
            PPKVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICD
Sbjct  181  PPKVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICD  240

Query  293  ARGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            ARGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR
Sbjct  241  ARGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  294


>gi|118616439|ref|YP_904771.1| UDP-glucose 4-epimerase, GalE3 [Mycobacterium ulcerans Agy99]
 gi|118568549|gb|ABL03300.1| UDP-glucose 4-epimerase, GalE3 [Mycobacterium ulcerans Agy99]
Length=346

 Score =  587 bits (1513),  Expect = 1e-165, Method: Compositional matrix adjust.
 Identities = 297/346 (86%), Positives = 318/346 (92%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            M+VLLTGAAGFIGSRV AAL AAGH+VVGVD LLPAAHGPNPVLPPGC RVDVRDA A+A
Sbjct  1    MKVLLTGAAGFIGSRVGAALSAAGHEVVGVDVLLPAAHGPNPVLPPGCHRVDVRDADAMA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQG YDCP+HG +DPLPRR +DLD GVFEHRCP C EPV W+LV E+A LRPRSLYAASK
Sbjct  121  GQGHYDCPEHGRIDPLPRRHSDLDAGVFEHRCPLCAEPVRWRLVGEEAELRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSE++GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS++EKG+PPKVFEDG
Sbjct  181  TAQEHYALAWSESTGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSSLEKGEPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDD+AAANLAA  LGE DR GF A NVCSGRPISILQVA+A+C ARG ++SP
Sbjct  241  GQMRDFVHVDDIAAANLAAAQLGEVDRHGFVAANVCSGRPISILQVASALCQARGDALSP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             ITG YRSGDVRHIVADP+RAA VLGFRAAV+P EGLR FAFAPLR
Sbjct  301  VITGQYRSGDVRHIVADPSRAAEVLGFRAAVEPLEGLRGFAFAPLR  346


>gi|342858955|ref|ZP_08715609.1| putative UDP-glucose 4-epimerase GALE3 [Mycobacterium colombiense 
CECT 3035]
 gi|342133196|gb|EGT86399.1| putative UDP-glucose 4-epimerase GALE3 [Mycobacterium colombiense 
CECT 3035]
Length=342

 Score =  568 bits (1463),  Expect = 6e-160, Method: Compositional matrix adjust.
 Identities = 299/346 (87%), Positives = 317/346 (92%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIG+RVDAALRAAGH+VVGVDALL AAHGPNPVLP GC RVDVRDA ALA
Sbjct  1    MRVLLTGAAGFIGARVDAALRAAGHEVVGVDALLAAAHGPNPVLPQGCHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVD+VCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRY C +HGPVDPLPRRRADLD G+FEHRCP  GE + W+LVDEDA LRPRSLYAASK
Sbjct  121  GQGRYHCDRHGPVDPLPRRRADLDAGIFEHRCPLGGEELHWRLVDEDACLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEA+GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSA+EKG PP+VFEDG
Sbjct  181  TAQEHYALAWSEATGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSALEKGDPPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAAN+AA   GE    GFTAVNVCSG+PI+I QVA A+CDARG S+SP
Sbjct  241  GQMRDFVHVDDVAAANVAATQWGE----GFTAVNVCSGQPIAISQVAAALCDARGASLSP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADPARAA VLGFRAAV P +GLREFAFAPLR
Sbjct  297  VVTGQYRSGDVRHIVADPARAAEVLGFRAAVAPRDGLREFAFAPLR  342


>gi|240171284|ref|ZP_04749943.1| UDP-glucose 4-epimerase, GalE3 [Mycobacterium kansasii ATCC 12478]
Length=346

 Score =  555 bits (1431),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 293/346 (85%), Positives = 313/346 (91%), Gaps = 0/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            M+VLLTGAAGFIGSRV  AL AAGH+VVGVDALLPAAHGP+  LPPGC RVDVRD  ALA
Sbjct  1    MKVLLTGAAGFIGSRVAVALSAAGHEVVGVDALLPAAHGPDAQLPPGCHRVDVRDGDALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGV+AADAP YG HND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVDAADAPEYGAHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRY C +HG VDPLPRRRADLD+G+FEHRCP CG+PV W+LVDE A +RPRSLYAASK
Sbjct  121  GQGRYHCGRHGLVDPLPRRRADLDSGIFEHRCPACGDPVRWRLVDEAAAVRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYALAWSE++GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS++EKG+PP+VFEDG
Sbjct  181  AAQEHYALAWSESTGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSSLEKGEPPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAA  L  ADR GFTA NVCSGRPISILQVA A+C+ARG S +P
Sbjct  241  GQMRDFVHVDDVAAANLAAADLTAADRGGFTAANVCSGRPISILQVAIALCEARGDSTAP  300

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             ITG YRSGDVRHIVADPARAA VLGFRAAV P EGLR+FAFAPLR
Sbjct  301  VITGQYRSGDVRHIVADPARAADVLGFRAAVAPVEGLRDFAFAPLR  346


>gi|254777045|ref|ZP_05218561.1| NAD-dependent epimerase/dehydratase [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|336460492|gb|EGO39387.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=342

 Score =  552 bits (1422),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 299/346 (87%), Positives = 319/346 (93%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TGAAGFIGSRV AALRAAGHDVV VDALL AAHGPNP+ P GC RVDVRDA ALA
Sbjct  1    MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVD+VCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQG Y C +HGPV PLPRRRADLD GVFEHRCP  GE + WQLVDEDA LRPRSLYAASK
Sbjct  121  GQGGYRCERHGPVHPLPRRRADLDAGVFEHRCPIGGEELRWQLVDEDACLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEA+GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSA+EKG+PP+VFEDG
Sbjct  181  TAQEHYALAWSEATGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSALEKGEPPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAA+      RDGFTAVNVCSG+PISILQVATA+CDARGG+++P
Sbjct  241  GQMRDFVHVDDVAAANLAALAC----RDGFTAVNVCSGQPISILQVATALCDARGGAVAP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADP+RAAR+LGFRAAV PG+GLREFAFAPLR
Sbjct  297  VVTGQYRSGDVRHIVADPSRAARLLGFRAAVQPGDGLREFAFAPLR  342


>gi|254818932|ref|ZP_05223933.1| NAD-dependent epimerase/dehydratase [Mycobacterium intracellulare 
ATCC 13950]
Length=342

 Score =  551 bits (1421),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 292/346 (85%), Positives = 310/346 (90%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRV AALRAAGHDVV VD LLPAAHGPNPVLP GC RVDVRDA ALA
Sbjct  1    MRVLLTGAAGFIGSRVGAALRAAGHDVVAVDVLLPAAHGPNPVLPKGCHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLL GVD VCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLDGVDAVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQG Y C +HG VDPLPRRRADLD G FEHRCP  GE + W+LVDEDA LRPRSLYAA K
Sbjct  121  GQGNYHCRRHGRVDPLPRRRADLDAGTFEHRCPVGGEELAWRLVDEDACLRPRSLYAAGK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEA+GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS++EKG+PP+VFEDG
Sbjct  181  TAQEHYALAWSEATGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSSLEKGEPPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAAN+AA     A  DGF A NVCSG+PISI +VA A+CDARGGS+SP
Sbjct  241  GQMRDFVHVDDVAAANVAA----LAHDDGFLAANVCSGQPISIFEVAAALCDARGGSLSP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADP+RAA VLGFRA+V PG+GLREFAFAPLR
Sbjct  297  VVTGQYRSGDVRHIVADPSRAAEVLGFRASVLPGDGLREFAFAPLR  342


>gi|118466473|ref|YP_883738.1| NAD-dependent epimerase/dehydratase [Mycobacterium avium 104]
 gi|118167760|gb|ABK68657.1| NAD-dependent epimerase/dehydratase [Mycobacterium avium 104]
Length=340

 Score =  546 bits (1407),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 296/344 (87%), Positives = 317/344 (93%), Gaps = 4/344 (1%)

Query  3    VLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPL  62
            +L+TGAAGFIGSRV AALRAAGHDVV VDALL AAHGPNP+ P GC RVDVRDA ALAPL
Sbjct  1    MLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALAPL  60

Query  63   LAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQ  122
            LAGVD+VCHQAAMVGAGV+AADAPAYGGHND ATTVLLAQMFAAGVRRLVLASSMVVYGQ
Sbjct  61   LAGVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVYGQ  120

Query  123  GRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTA  182
            G Y C +HGPV PLPRRRADLD GVFEHRCP  GE + WQLVDEDA LRPRSLYAASKTA
Sbjct  121  GGYRCERHGPVHPLPRRRADLDAGVFEHRCPIGGEELRWQLVDEDACLRPRSLYAASKTA  180

Query  183  QEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQ  242
            QEHYALAWSEA+GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSA+EKG+PP+VFEDGGQ
Sbjct  181  QEHYALAWSEATGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSALEKGEPPRVFEDGGQ  240

Query  243  MRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAI  302
            MRDFVHVDDVAAANLAA+      RDGFTAVNVCSG+PISILQVATA+CDARGG+++P +
Sbjct  241  MRDFVHVDDVAAANLAALAC----RDGFTAVNVCSGQPISILQVATALCDARGGAVAPVV  296

Query  303  TGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            TG YRSGDVRHIVADP+RAAR+LGFRAAV PG+GLREFAFAPLR
Sbjct  297  TGQYRSGDVRHIVADPSRAARLLGFRAAVQPGDGLREFAFAPLR  340


>gi|289749034|ref|ZP_06508412.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T92]
 gi|289689621|gb|EFD57050.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis T92]
Length=338

 Score =  535 bits (1379),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 269/270 (99%), Positives = 269/270 (99%), Gaps = 0/270 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALL AAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLAAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGF  270
            GQMRDFVHVDDVAAANLAAVHLGEADRDGF
Sbjct  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGF  270


>gi|108797684|ref|YP_637881.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS]
 gi|119866772|ref|YP_936724.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS]
 gi|108768103|gb|ABG06825.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS]
 gi|119692861|gb|ABL89934.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS]
Length=343

 Score =  509 bits (1310),  Expect = 3e-142, Method: Compositional matrix adjust.
 Identities = 269/346 (78%), Positives = 294/346 (85%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRV AAL +AGH+VV VD +LPAAHG    LP    RVDVRDA ALA
Sbjct  1    MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLL GVD VCHQAA+VGAGVNAADAP+YG HND+ TTVLLA+MFAAGVR+LVLASSMVVY
Sbjct  61   PLLEGVDAVCHQAAVVGAGVNAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGR+DCP HGPVDPLPR RADLD GVFEHRCP  GE + W+LV ED P+RPRSLYAASK
Sbjct  121  GQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQWRLVGEDEPVRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYALAW+EA+GGSVVALRYHNVYGP MPRDTPYSGVAAIFRS +E G  P+VFEDG
Sbjct  181  AAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAA+   EAD  GF A NVCSGRPISI++VA+ +C+ RG +  P
Sbjct  241  GQMRDFVHVDDVAAANLAAI---EADLPGFEAFNVCSGRPISIIEVASELCEIRGAA-PP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVA P RAA  LGFRA VDP +GLREFAFAPLR
Sbjct  297  LVTGQYRSGDVRHIVASPRRAAEQLGFRAVVDPRDGLREFAFAPLR  342


>gi|126433309|ref|YP_001069000.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS]
 gi|126233109|gb|ABN96509.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS]
Length=343

 Score =  508 bits (1309),  Expect = 5e-142, Method: Compositional matrix adjust.
 Identities = 267/346 (78%), Positives = 292/346 (85%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRV AAL +AGH+VV VD +LPAAHG    LP    RVDVRDA ALA
Sbjct  1    MRVLLTGAAGFIGSRVRAALESAGHEVVAVDVMLPAAHGGAAPLPEDTHRVDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLL GVD VCHQAA+VGAGVNAADAP+YG HND+ TTVLLA+MFAAGVR+LVLASSMVVY
Sbjct  61   PLLEGVDAVCHQAAVVGAGVNAADAPSYGSHNDYGTTVLLAEMFAAGVRKLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGR+DCP HGPVDPLPR RADLD GVFEHRCP  GE + W+LV ED P+RPRSLYAASK
Sbjct  121  GQGRFDCPAHGPVDPLPRTRADLDAGVFEHRCPVGGEELQWRLVGEDEPVRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYALAW+EA+GGSVVALRYHNVYGP MPRDTPYSGVAAIFRS +E G  P+VFEDG
Sbjct  181  AAQEHYALAWAEATGGSVVALRYHNVYGPHMPRDTPYSGVAAIFRSELENGDVPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAA+  G     GF A NVCSGRPISI++VA+ +C+ RG +  P
Sbjct  241  GQMRDFVHVDDVAAANLAAIEAG---LPGFEAFNVCSGRPISIIEVASELCEIRGAA-PP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVA P RAA  LGFRA VDP +GLREFAFAPLR
Sbjct  297  LVTGQYRSGDVRHIVASPRRAAEQLGFRAVVDPRDGLREFAFAPLR  342


>gi|118469353|ref|YP_885393.1| NAD-dependent epimerase/dehydratase [Mycobacterium smegmatis 
str. MC2 155]
 gi|118170640|gb|ABK71536.1| NAD-dependent epimerase/dehydratase [Mycobacterium smegmatis 
str. MC2 155]
Length=346

 Score =  490 bits (1261),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 259/346 (75%), Positives = 285/346 (83%), Gaps = 1/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSR+  ALR AGH+V+GVDA+LPAAH      P GC+ +DVRDA ALA
Sbjct  1    MRVLLTGAAGFIGSRIAVALRDAGHEVIGVDAMLPAAHRTGAQPPEGCELIDVRDADALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLL+GVD+VCHQAA+VGAGVN  DAP+Y  HN   T VLLAQMF AG  RLVLASSMVVY
Sbjct  61   PLLSGVDVVCHQAAVVGAGVNPGDAPSYASHNVLGTAVLLAQMFEAGCTRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGR+ C +HG +DP+PR RADLD GVFEHRCP   EP+ WQLV EDAP+RPRSLYAASK
Sbjct  121  GQGRFYCVEHGEIDPMPRSRADLDAGVFEHRCPVGEEPLRWQLVGEDAPVRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYALAW+ A GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRS +E G  P+VFEDG
Sbjct  181  AAQEHYALAWAVAVGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSQLESGDVPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAANLAAVH  +   DGF   NVCSGRPISI+ VAT +C+ RG    P
Sbjct  241  GQMRDFVHVDDVAAANLAAVHAVDGGLDGFHPFNVCSGRPISIMDVATQLCEVRGAP-GP  299

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADPARA  VLGFRAA+DP +GLREFAFA LR
Sbjct  300  VVTGQYRSGDVRHIVADPARAHEVLGFRAAIDPRDGLREFAFARLR  345


>gi|254230879|ref|ZP_04924206.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis C]
 gi|124599938|gb|EAY58948.1| UDP-glucose 4-epimerase galE3 [Mycobacterium tuberculosis C]
Length=359

 Score =  486 bits (1251),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 241/241 (100%), Positives = 241/241 (100%), Gaps = 0/241 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA
Sbjct  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
            PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY
Sbjct  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK
Sbjct  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
            TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG
Sbjct  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240

Query  241  G  241
            G
Sbjct  241  G  241


>gi|120401897|ref|YP_951726.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954715|gb|ABM11720.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii 
PYR-1]
Length=348

 Score =  457 bits (1175),  Expect = 1e-126, Method: Compositional matrix adjust.
 Identities = 264/346 (77%), Positives = 291/346 (85%), Gaps = 4/346 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVLLTGAAGFIG+R+   L   GHDVV VDA+LPAAHG +   P    RVDVRDA+A+A
Sbjct  1    MRVLLTGAAGFIGTRIRERLIDGGHDVVAVDAMLPAAHGEDAAPPDDVARVDVRDAAAVA  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              +AGVD+VCHQAA+VGAGV+AADAP+Y  HNDFAT VLLAQMF AG RRLVLASSMVVY
Sbjct  61   DAVAGVDVVCHQAAVVGAGVDAADAPSYAAHNDFATAVLLAQMFGAGCRRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            GQGRY CP HG VDP+PR R+DLD G F+HRCP CGEPV W LV E APLRPRSLYAASK
Sbjct  121  GQGRYVCPGHGDVDPVPRTRSDLDAGAFDHRCPICGEPVDWALVGEGAPLRPRSLYAASK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYALAWSE++GGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSA+E G  P+VFEDG
Sbjct  181  VAQEHYALAWSESTGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSALEAGDVPRVFEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
            GQMRDFVHVDDVAAAN+AAV  G    +GF A NVCSG+P+SIL VATA+C+AR G +SP
Sbjct  241  GQMRDFVHVDDVAAANVAAVEAGT---EGFNAFNVCSGKPVSILDVATALCEAR-GDVSP  296

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YRSGDVRHIVADPARAA VLGFRA VDP +GL EFA APLR
Sbjct  297  LVTGQYRSGDVRHIVADPARAADVLGFRAVVDPADGLCEFATAPLR  342


>gi|226363583|ref|YP_002781365.1| nucleotide-sugar epimerase [Rhodococcus opacus B4]
 gi|226242072|dbj|BAH52420.1| putative nucleotide-sugar epimerase [Rhodococcus opacus B4]
Length=355

 Score =  395 bits (1015),  Expect = 5e-108, Method: Compositional matrix adjust.
 Identities = 222/345 (65%), Positives = 255/345 (74%), Gaps = 4/345 (1%)

Query  2    RVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAP  61
            RVLLTGAAGFIG  V  AL  AGHDVV VDALLP+AHG    LP G +R DVRD  AL  
Sbjct  5    RVLLTGAAGFIGGHVRTALTEAGHDVVAVDALLPSAHGAGAELPDGVRRADVRDLPALTE  64

Query  62   LLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYG  121
            LL GVD+VCHQAA+VGAGV+ +DAPAY  HND  T  LLA M  +G RR+VLASSMVVYG
Sbjct  65   LLRGVDVVCHQAAVVGAGVDVSDAPAYASHNDLGTATLLAAMHRSGCRRMVLASSMVVYG  124

Query  122  QGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKT  181
             GRY   +   V+P  RR  DL  G+F+   PG GEP+ W LV+E++PLRPRSLYAA K 
Sbjct  125  AGRYRNGRGEFVEPAARRAEDLAAGIFDETDPGTGEPLEWALVEENSPLRPRSLYAAGKV  184

Query  182  AQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGG  241
            AQE+YALAW+ A+GGSV ALRYHNVYG  MP +TPYSGVAA+FRSA+E G+PP+VFEDG 
Sbjct  185  AQENYALAWALATGGSVTALRYHNVYGDRMPHNTPYSGVAAMFRSALEAGEPPRVFEDGR  244

Query  242  QMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPA  301
            Q RDFVHV DVAAAN+AAV   EA   GF A NVCSG+PI+I +VA  +  + GG   P 
Sbjct  245  QTRDFVHVHDVAAANVAAV---EAALPGFAAFNVCSGQPITIGEVAATLARSHGGP-EPV  300

Query  302  ITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            +TG YR GDVRHIVADP RA   LGFRA + P EG+  FA APLR
Sbjct  301  VTGEYRPGDVRHIVADPRRARERLGFRAKILPDEGIAAFAHAPLR  345


>gi|111021237|ref|YP_704209.1| UDP-glucose 4-epimerase [Rhodococcus jostii RHA1]
 gi|110820767|gb|ABG96051.1| UDP-glucose 4-epimerase [Rhodococcus jostii RHA1]
Length=355

 Score =  384 bits (986),  Expect = 1e-104, Method: Compositional matrix adjust.
 Identities = 219/345 (64%), Positives = 249/345 (73%), Gaps = 4/345 (1%)

Query  2    RVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAP  61
            RVLLTGAAGFIG  V AAL  AGHDVV VDALLP+AHG +P  P G +R DVRD  AL  
Sbjct  5    RVLLTGAAGFIGGHVHAALIEAGHDVVAVDALLPSAHGADPEPPDGVRRADVRDRPALIE  64

Query  62   LLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYG  121
            LL GVD+VCHQAA+VGAGV+  DAPAY  HND  T  LLA M  +G   L+LASSMVVYG
Sbjct  65   LLRGVDVVCHQAAVVGAGVDVRDAPAYASHNDLGTATLLAAMHESGCETLILASSMVVYG  124

Query  122  QGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKT  181
            +GRY   +   V+P  RR  DL  G F+   P  GEP+ W LV+E +PLRPRSLYAA K 
Sbjct  125  EGRYRNGRGEFVEPAARRAEDLAAGFFDETDPDTGEPLEWALVEEHSPLRPRSLYAAGKV  184

Query  182  AQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGG  241
            AQE+YALAW+ A+GGSV ALRYHNVYG  MPR+TPYSGVAA+FRSA+E G PP VFEDG 
Sbjct  185  AQENYALAWALATGGSVTALRYHNVYGDRMPRNTPYSGVAAMFRSALENGDPPHVFEDGR  244

Query  242  QMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPA  301
            Q RDFVHV DVAAAN+AAV   EA   GF A NVCSG PI+I +VA  +  + GG   P 
Sbjct  245  QTRDFVHVHDVAAANVAAV---EAALPGFAAFNVCSGHPITIGEVAATLARSHGGP-EPV  300

Query  302  ITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            +TG YR GDVRHIVADP  A   LGFRA + P +G+  FA APLR
Sbjct  301  VTGEYRPGDVRHIVADPWLARERLGFRAQIRPADGIAAFAHAPLR  345


>gi|320012487|gb|ADW07337.1| NAD-dependent epimerase/dehydratase [Streptomyces flavogriseus 
ATCC 33331]
Length=352

 Score =  380 bits (976),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 209/350 (60%), Positives = 250/350 (72%), Gaps = 5/350 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPN-PVLPPGCQRV--DVRDAS  57
            MRVL+TG AGFIGS++   L A GH+ V +DALLP+AHG + P  PPG + V  DVRD  
Sbjct  1    MRVLVTGGAGFIGSQIVRTLAADGHEPVVLDALLPSAHGASVPPPPPGVRSVVADVRDRE  60

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
            A+A  L G+D VCHQAAMVG G + ADAP Y G NDF T VLLA+M AAG+R LVLA SM
Sbjct  61   AVAGALTGIDAVCHQAAMVGLGKDFADAPQYVGCNDFGTAVLLAEMAAAGIRYLVLAGSM  120

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+GRYDCP+HG V P PR  ADLD G FE RCP C   ++  LV EDAP+ PR++YA
Sbjct  121  VVYGEGRYDCPRHGGVRPGPRSVADLDAGRFEPRCPSCRSELVPGLVTEDAPVDPRNVYA  180

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            A+K AQEH A AW+ A+GG  VALRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+VF
Sbjct  181  ATKLAQEHLAAAWTRATGGRAVALRYHNVYGPGMPRDTPYAGVASFFRSALARGESPRVF  240

Query  238  EDGGQMRDFVHVDDVAAANLAAV-HLGEADRDGFTAVNVCSGRPISILQVATAICDARGG  296
            EDGGQ RDFVHV DVA AN+ A+  L E     F A N  SG P +I ++A A+  A GG
Sbjct  241  EDGGQRRDFVHVRDVATANVTALAALRERGPGSFDAYNTGSGVPHTIGEMAWALASAHGG  300

Query  297  SMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              +P +TG YR GDVRH+ AD  R    LG++ A D   G+REFA  PLR
Sbjct  301  P-APVVTGEYRLGDVRHVTADSRRLREELGWKPATDFVTGMREFATEPLR  349


>gi|325000783|ref|ZP_08121895.1| UDP-glucose 4-epimerase [Pseudonocardia sp. P1]
Length=353

 Score =  369 bits (948),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 215/349 (62%), Positives = 249/349 (72%), Gaps = 6/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV---DVRDAS  57
            MRVLLTG AGFIGS V   L A GHDVV +DALLP AHGP  V P G   +   DVRDA 
Sbjct  1    MRVLLTGGAGFIGSHVADRLTADGHDVVLLDALLPQAHGPGAV-PDGDHELVHGDVRDAD  59

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
             +  LL+GVD VCHQAAMVG GV+ +DAP Y  HND  T VLLAQM AAGV RLVLA SM
Sbjct  60   LVRRLLSGVDAVCHQAAMVGHGVDPSDAPDYAAHNDLGTAVLLAQMHAAGVHRLVLAGSM  119

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+GRYDCP HG V P PR   D+D G +E RCP CG+ +   LV E AP+ PRS YA
Sbjct  120  VVYGEGRYDCPDHGVVRPGPRAFDDIDAGRYEPRCPECGKDLEPGLVPESAPVDPRSTYA  179

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            A+K AQEH A AW+  +GG+V +LRYHNVYGP MPRDTPY+GVA+IFRSA+E+G+ P+V 
Sbjct  180  ATKLAQEHLASAWARQTGGTVWSLRYHNVYGPRMPRDTPYAGVASIFRSALERGEAPRVM  239

Query  238  EDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGS  297
            EDG Q RDFVHV DVAAAN AA+ L + +  GF A NVCSG P +I  +A  +  A GG 
Sbjct  240  EDGRQRRDFVHVSDVAAANAAAL-LADPEPTGFGAANVCSGEPHTIGDLAAELARAMGGP  298

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +P ITG  R GDVRH+VADP+ AA  LGFRAA    +G+  FA  PLR
Sbjct  299  -APEITGGARPGDVRHVVADPSYAASRLGFRAATSFADGVTAFATDPLR  346


>gi|182440498|ref|YP_001828217.1| putative UDP-glucose 4-epimerase [Streptomyces griseus subsp. 
griseus NBRC 13350]
 gi|178469014|dbj|BAG23534.1| putative UDP-glucose 4-epimerase [Streptomyces griseus subsp. 
griseus NBRC 13350]
Length=372

 Score =  368 bits (944),  Expect = 8e-100, Method: Compositional matrix adjust.
 Identities = 207/353 (59%), Positives = 244/353 (70%), Gaps = 11/353 (3%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV---DVRDAS  57
            MRVL+TG AGFIGS V AAL AAGH+ V +DALLP+AH       P   RV   DVRD  
Sbjct  1    MRVLVTGGAGFIGSHVVAALTAAGHESVVLDALLPSAHPGPTPPKPPADRVVVGDVRDRE  60

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
            A+A  LAGVD VCHQAAMVG G + ADAP Y G ND  T VLLA+M  AGVR LVLA SM
Sbjct  61   AVADALAGVDTVCHQAAMVGLGKDFADAPLYVGCNDLGTAVLLAEMATAGVRDLVLAGSM  120

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+GRY CP+HG V P PR  ADL  G FE RCP CG  +   LV EDAP  PR++YA
Sbjct  121  VVYGEGRYACPRHGTVRPGPRAEADLRAGSFEPRCPDCGAELTPGLVGEDAPADPRNVYA  180

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            ++K AQEH A AW+ A+GG  V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+V+
Sbjct  181  STKLAQEHLAAAWTRATGGRAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVY  240

Query  238  EDGGQMRDFVHVDDVAAANLAAVHLGEADRD----GFTAVNVCSGRPISILQVATAICDA  293
            EDG Q RDFVHV DVA+AN  A+   EA R+     F A N  SG P +I ++A+A+  A
Sbjct  241  EDGAQRRDFVHVHDVASANAVAL---EAVRERRPASFAAYNTGSGEPHTIGEMASALARA  297

Query  294  RGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             GG   P +TG YR GDVRH+ AD       LG+R  V   EG+R+FA APLR
Sbjct  298  HGGP-DPVVTGEYRLGDVRHVTADSRALREELGWRPRVSFAEGMRDFAAAPLR  349


>gi|326781168|ref|ZP_08240433.1| UDP-glucose 4-epimerase [Streptomyces cf. griseus XylebKG-1]
 gi|326661501|gb|EGE46347.1| UDP-glucose 4-epimerase [Streptomyces griseus XylebKG-1]
Length=372

 Score =  367 bits (942),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 207/353 (59%), Positives = 244/353 (70%), Gaps = 11/353 (3%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV---DVRDAS  57
            MRVL+TG AGFIGS V AAL AAGH+ V +DALLP+AH       P   RV   DVRD  
Sbjct  1    MRVLVTGGAGFIGSHVVAALTAAGHESVVLDALLPSAHPGPTPPKPPGDRVVVGDVRDRE  60

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
            A+A  LAGVD VCHQAAMVG G + ADAP Y G ND  T VLLA+M  AGVR LVLA SM
Sbjct  61   AVADALAGVDAVCHQAAMVGLGKDFADAPLYVGCNDLGTAVLLAEMATAGVRDLVLAGSM  120

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+GRY CP+HG V P PR  ADL  G FE RCP CG  +   LV EDAP  PR++YA
Sbjct  121  VVYGEGRYACPRHGTVRPGPRAEADLRAGSFEPRCPDCGAELTPGLVGEDAPADPRNVYA  180

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            ++K AQEH A AW+ A+GG  V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+V+
Sbjct  181  STKLAQEHLAAAWARATGGRAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVY  240

Query  238  EDGGQMRDFVHVDDVAAANLAAVHLGEADRD----GFTAVNVCSGRPISILQVATAICDA  293
            EDG Q RDFVHV DVA+AN  A+   EA R+     F A N  SG P +I ++A+A+  A
Sbjct  241  EDGAQRRDFVHVHDVASANAVAL---EAVRERRPASFAAYNTGSGEPHTIGEMASALARA  297

Query  294  RGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             GG   P +TG YR GDVRH+ AD       LG+R  V   EG+R+FA APLR
Sbjct  298  HGGP-DPVVTGEYRLGDVRHVTADSRALREELGWRPRVSFAEGMRDFAAAPLR  349


>gi|300790126|ref|YP_003770417.1| UDP-glucose 4-epimerase [Amycolatopsis mediterranei U32]
 gi|299799640|gb|ADJ50015.1| UDP-glucose 4-epimerase [Amycolatopsis mediterranei U32]
 gi|340531806|gb|AEK47011.1| UDP-glucose 4-epimerase [Amycolatopsis mediterranei S699]
Length=356

 Score =  361 bits (927),  Expect = 8e-98, Method: Compositional matrix adjust.
 Identities = 194/350 (56%), Positives = 244/350 (70%), Gaps = 6/350 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQ----RVDVRDA  56
            +RVL+TG AGFIGS +   L   G +VV +D LLP AHG +   P   +    R DV D 
Sbjct  4    VRVLVTGGAGFIGSHIADLLADGGDEVVVLDNLLPTAHGSSSPPPYTGRHRFLRGDVTDT  63

Query  57   SALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASS  116
              +A LL GVD VCHQAA+VG G++ +DAP+Y  HND+ T VLLA M AAGVR+LVLASS
Sbjct  64   EIVAELLDGVDAVCHQAAVVGHGIDPSDAPSYALHNDYGTAVLLAGMHAAGVRKLVLASS  123

Query  117  MVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLY  176
            MVVYG+GRY CP HG V P PRRR+D+D G FE RCP C   + WQLV EDAPL PRS Y
Sbjct  124  MVVYGEGRYACPDHGVVPPSPRRRSDVDAGRFEPRCPSCEAELSWQLVPEDAPLNPRSTY  183

Query  177  AASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKV  236
            AA+K AQEH A AW+  +GG+V A+RYHNVYGP MP++TPY+GVA++FRSA+ +G+ P+V
Sbjct  184  AATKLAQEHLAGAWARQTGGTVWAMRYHNVYGPRMPQNTPYAGVASLFRSALVRGEAPRV  243

Query  237  FEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGG  296
             EDG Q RDF+HV DVA AN+ A+H+ E      + +NVCSG P ++  +AT +  A  G
Sbjct  244  LEDGRQQRDFIHVHDVARANVLALHM-EGPAGEISPLNVCSGTPHTVGDLATELARASKG  302

Query  297  SMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              +P + G  R  DVRH+VADPARA   LGF A +   +G+ +FA A LR
Sbjct  303  P-APKVIGGARPADVRHVVADPARAREQLGFTAEIGFADGIADFATAELR  351


>gi|302530361|ref|ZP_07282703.1| UDP-glucose 4-epimerase [Streptomyces sp. AA4]
 gi|302439256|gb|EFL11072.1| UDP-glucose 4-epimerase [Streptomyces sp. AA4]
Length=353

 Score =  358 bits (920),  Expect = 5e-97, Method: Compositional matrix adjust.
 Identities = 199/352 (57%), Positives = 242/352 (69%), Gaps = 10/352 (2%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV------DVR  54
            MRVLLTG AGFIGSR+   L   G +VV +D LL  AHG     PP   R       DV 
Sbjct  1    MRVLLTGGAGFIGSRIADQLADDGDEVVVLDNLLSTAHGST--TPPEYTRRHRFLRGDVT  58

Query  55   DASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLA  114
            D   +A LL GVD VCHQAA+VG GV+ +DAP+Y  +ND+ T VLLA M AA VR+LVLA
Sbjct  59   DTEIVAALLDGVDAVCHQAAVVGHGVDPSDAPSYALNNDYGTAVLLAAMHAAKVRKLVLA  118

Query  115  SSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRS  174
            SSMVVYG+GRY C +HG V P PRR++D+D G FE  CP CG  + WQLV E+APL PRS
Sbjct  119  SSMVVYGEGRYACAEHGVVPPSPRRQSDVDAGRFEPACPHCGAELGWQLVPENAPLLPRS  178

Query  175  LYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPP  234
             YAA+K AQEH A AW+  +GG+V ALRYHNVYGP MP++TPY+GVA++FRSA+E+G+ P
Sbjct  179  TYAATKLAQEHLAGAWARQTGGTVWALRYHNVYGPRMPQNTPYAGVASLFRSALERGEAP  238

Query  235  KVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDAR  294
             V EDG Q RDFVHVDDVA AN+ A+     + D  T +N+CSG+P S+  +A  +  A 
Sbjct  239  TVLEDGRQQRDFVHVDDVARANVLALRNDGPEAD-LTPLNICSGQPHSVGDLARELARAC  297

Query  295  GGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            GG   P I G  R  DVRH+VADPARA  +LGF+A     EG+  FA A LR
Sbjct  298  GGP-EPRIVGGARPADVRHVVADPARARELLGFQAETSFAEGIAAFATAELR  348


>gi|290955581|ref|YP_003486763.1| epimerase/dehydratase [Streptomyces scabiei 87.22]
 gi|260645107|emb|CBG68193.1| putative epimerase/dehydratase [Streptomyces scabiei 87.22]
Length=350

 Score =  358 bits (920),  Expect = 6e-97, Method: Compositional matrix adjust.
 Identities = 203/349 (59%), Positives = 239/349 (69%), Gaps = 4/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGC--QRVDVRDASA  58
            M +L+TG AGFIGS V  AL  AGH V  +DALLPAAH   P +PPG   +  DVRD +A
Sbjct  1    MLILVTGGAGFIGSHVVTALIGAGHTVRVLDALLPAAHRTAPQIPPGVDWRHADVRDKAA  60

Query  59   LAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMV  118
            +   L GV  VCHQAAMVG G + ADAP Y G ND  T VLLA M  AGVR LVLA SMV
Sbjct  61   VTDALRGVGAVCHQAAMVGLGKDFADAPDYVGCNDLGTAVLLAGMAEAGVRHLVLAGSMV  120

Query  119  VYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAA  178
            VYG+G Y C +HG V P PR  ADL+ G FE  CP CGEP+   LVDEDAP  PR++YAA
Sbjct  121  VYGEGHYACSRHGVVRPGPRLVADLEAGRFEPPCPHCGEPLTGGLVDEDAPADPRNVYAA  180

Query  179  SKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFE  238
            +K AQEH A AW+ A+GG   ALRYHNVYGPGMPRDTPY+GVA++FRSA+ +G+ P+VFE
Sbjct  181  TKLAQEHLAAAWARATGGRASALRYHNVYGPGMPRDTPYAGVASLFRSALARGEVPRVFE  240

Query  239  DGGQMRDFVHVDDVAAANLAAVH-LGEADRDGFTAVNVCSGRPISILQVATAICDARGGS  297
            DGGQ RDFVHV DVA ANLAA+  +      G  A NV SG P ++ ++ATA+  A  G 
Sbjct  241  DGGQRRDFVHVRDVAGANLAALDGVRGLPEGGLRAYNVGSGEPHTVGEMATALA-ASYGD  299

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              P +TG +R GDVRHI A   R    LG++  V   EG+ EFA APLR
Sbjct  300  RVPVVTGEFRLGDVRHITASSRRLREELGWKPQVAFAEGMAEFAAAPLR  348


>gi|302868412|ref|YP_003837049.1| NAD-dependent epimerase/dehydratase [Micromonospora aurantiaca 
ATCC 27029]
 gi|302571271|gb|ADL47473.1| NAD-dependent epimerase/dehydratase [Micromonospora aurantiaca 
ATCC 27029]
Length=353

 Score =  357 bits (915),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 204/351 (59%), Positives = 240/351 (69%), Gaps = 10/351 (2%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV-----DVRD  55
            MRVL+TGAAGFIGS+V   L A GH VV +DALLP AHG  P  P   +R      D+RD
Sbjct  1    MRVLVTGAAGFIGSQVADLLVAQGHQVVCLDALLPQAHGSEP--PEWFRRHEPVVGDIRD  58

Query  56   ASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLAS  115
            A  L  LLAGVD VCHQAAMVG G++ +DAP Y  HND+ T VLLA M  AGV RLVLAS
Sbjct  59   AHLLDDLLAGVDAVCHQAAMVGHGLDPSDAPDYVSHNDYGTAVLLAAMHRAGVSRLVLAS  118

Query  116  SMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSL  175
            SMVVYG+GRY C +HG V P PRR AD+  G ++  CP C   +   LV EDAPL PRS 
Sbjct  119  SMVVYGEGRYTCARHGVVRPAPRRAADVAVGRYDPTCPVCAGALASALVPEDAPLEPRST  178

Query  176  YAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPK  235
            YAASK AQE+ A AWS  +G  V ALRYHNVYGP MPRDTPY+GVA+IFRSA+  G+PP+
Sbjct  179  YAASKLAQENLAAAWSRQTGAGVWALRYHNVYGPRMPRDTPYAGVASIFRSALAHGRPPR  238

Query  236  VFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARG  295
            ++EDG Q RDFVHV DVA AN+ A  L     DG   VNVCSGRP ++  +ATA+  A  
Sbjct  239  LYEDGLQQRDFVHVSDVARANVLA--LTAPAPDGLVPVNVCSGRPHTVGDLATALAAAMD  296

Query  296  GSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            G  +P + G  R  DVRH+VADP RA  +LG+ A V   +G+  FA  PLR
Sbjct  297  GP-APVVVGGARPADVRHVVADPRRARDLLGYTARVSFADGVAAFATDPLR  346


>gi|291453182|ref|ZP_06592572.1| epimerase [Streptomyces albus J1074]
 gi|291356131|gb|EFE83033.1| epimerase [Streptomyces albus J1074]
Length=355

 Score =  354 bits (909),  Expect = 1e-95, Method: Compositional matrix adjust.
 Identities = 206/349 (60%), Positives = 241/349 (70%), Gaps = 5/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV--DVRDASA  58
            MRVL+TG AGFIGS+V   L AAGH+ V  DALLPAAH P    P   + V  D+RDA  
Sbjct  1    MRVLVTGGAGFIGSQVVRELAAAGHEAVVFDALLPAAH-PGGHGPREARSVVADLRDAER  59

Query  59   LAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMV  118
            +   LAG+D VCHQAAMVG G   ADAPAY G ND  T VLLA+M AAGVR LV+A SMV
Sbjct  60   VRAALAGIDAVCHQAAMVGLGKEFADAPAYVGCNDLGTAVLLAEMAAAGVRDLVVAGSMV  119

Query  119  VYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAA  178
            VYG+GRYDC +HG V P PR  ADLD G FE  CP CG P+   LV EDAP  PR++YAA
Sbjct  120  VYGEGRYDCARHGTVRPGPRAAADLDAGRFEPPCPECGAPLRPGLVAEDAPTDPRNVYAA  179

Query  179  SKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFE  238
            +K AQEH A AWS A+GG  VALRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+V+E
Sbjct  180  TKLAQEHLASAWSRATGGRAVALRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVYE  239

Query  239  DGGQMRDFVHVDDVAAANLAAVHLGEADRDG-FTAVNVCSGRPISILQVATAICDARGGS  297
            DG Q RDFVHV DVA+AN  A+        G F A N  SG P +I ++A A+  A GG 
Sbjct  240  DGAQRRDFVHVRDVASANTVALAALAGREPGFFAAYNTGSGEPHTIGEMAAALAAAHGGP  299

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +P +TG YR GDVRH+ AD  R    LG++  V   EG+ EFA APLR
Sbjct  300  -APVVTGEYRLGDVRHVTADSRRLRDELGWKPQVGFAEGMAEFAAAPLR  347


>gi|306416865|gb|ADM87279.1| putative UDP-glucose 4-epimerase [Streptomyces subtropicus]
Length=372

 Score =  352 bits (904),  Expect = 4e-95, Method: Compositional matrix adjust.
 Identities = 207/351 (59%), Positives = 247/351 (71%), Gaps = 7/351 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAH-GPNPVLPPGCQRV---DVRDA  56
            MRVL+TG AGFIGS V AAL AAGH+ V +DALLP+AH G  P   PG  RV   DVRD 
Sbjct  1    MRVLITGGAGFIGSHVVAALAAAGHESVVLDALLPSAHPGGTPPQLPG-DRVAVGDVRDR  59

Query  57   SALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASS  116
             A+A  LAGVD VCHQAAMVG G + +DAP Y G ND  T VLLA+M +AGVR LVLA S
Sbjct  60   EAVADALAGVDAVCHQAAMVGLGKDFSDAPLYVGCNDLGTAVLLAEMASAGVRDLVLAGS  119

Query  117  MVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLY  176
            MVVYG+GRY+C +HG V P PR  ADL  G +E RCP CG  +   LV EDAP+ PR++Y
Sbjct  120  MVVYGEGRYECSRHGTVRPGPRAEADLRAGDYEPRCPHCGTALTPGLVTEDAPVDPRNVY  179

Query  177  AASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKV  236
            A++K AQEH A AW+ A+GG  V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+V
Sbjct  180  ASTKLAQEHLAAAWARATGGRAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRV  239

Query  237  FEDGGQMRDFVHVDDVAAANLAAVHLGEADRD-GFTAVNVCSGRPISILQVATAICDARG  295
            +EDGGQ RDFVHV DVAAAN  A+      R   F A N  SG P +I ++A A+ DA G
Sbjct  240  YEDGGQRRDFVHVHDVAAANAVALEAVRERRPASFAAYNTGSGEPHTIGEMAAALADAHG  299

Query  296  GSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            G   P +TG YR GDVRH+ AD       LG+R  V   EG+++FA APLR
Sbjct  300  GP-DPVVTGEYRLGDVRHVTADSRALREELGWRPRVSFAEGMKDFASAPLR  349


>gi|134099884|ref|YP_001105545.1| UDP-glucose 4-epimerase [Saccharopolyspora erythraea NRRL 2338]
 gi|291006079|ref|ZP_06564052.1| UDP-glucose 4-epimerase [Saccharopolyspora erythraea NRRL 2338]
 gi|133912507|emb|CAM02620.1| UDP-glucose 4-epimerase [Saccharopolyspora erythraea NRRL 2338]
Length=355

 Score =  352 bits (902),  Expect = 7e-95, Method: Compositional matrix adjust.
 Identities = 204/346 (59%), Positives = 238/346 (69%), Gaps = 2/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MR+L+TGAAGFIGS V  AL   GHDVV +DALLP AH   P +       DVRDA  + 
Sbjct  1    MRILVTGAAGFIGSHVADALAGRGHDVVLLDALLPQAHSTAPDIGHHLVHGDVRDAELVR  60

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
             LL+GV++VCHQAAMVG GV+ +D P Y  HND AT VLLA M A GV RLVLASSMVVY
Sbjct  61   DLLSGVEVVCHQAAMVGHGVDPSDMPDYASHNDHATAVLLAAMHATGVGRLVLASSMVVY  120

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+GRY CP+HG V P  RR+ DLD G ++ RCP CG  +   LV EDAPL PRS YAA+K
Sbjct  121  GEGRYRCPEHGVVRPSARRQDDLDAGRYDPRCPSCGAVLDPDLVPEDAPLDPRSTYAATK  180

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+  +GG V ALRYHNVYGP MP  TPY+GVA++FRSA+++G+ P V EDG
Sbjct  181  LAQEHLAAAWARQTGGGVWALRYHNVYGPRMPSGTPYAGVASLFRSALQRGEAPLVLEDG  240

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q RDFVHV DVAAAN  AV        G  AVNVCSG+P +I  +A  +  A GG   P
Sbjct  241  RQRRDFVHVHDVAAANALAV-EAAPPAGGLEAVNVCSGQPHTIGDMAEELSRAFGGP-RP  298

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             I G  R  DVRH+VADPA+A RVL FRA +   EG+  FA  PLR
Sbjct  299  RIVGGARPNDVRHVVADPAKARRVLDFRAEIGFREGMTAFASDPLR  344


>gi|302538232|ref|ZP_07290574.1| epimerase [Streptomyces sp. C]
 gi|302447127|gb|EFL18943.1| epimerase [Streptomyces sp. C]
Length=353

 Score =  351 bits (901),  Expect = 9e-95, Method: Compositional matrix adjust.
 Identities = 200/348 (58%), Positives = 238/348 (69%), Gaps = 3/348 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPG-CQRVDVRDASAL  59
            MRVL+TG AGFIGS V A L A GH  V +DALLPAAH   P LP     R DVRDA A+
Sbjct  1    MRVLVTGGAGFIGSHVVAVLAAGGHTPVVLDALLPAAHPRAPELPDAEVVRGDVRDAEAV  60

Query  60   APLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVV  119
               L GVD VCHQAAMVG G + ADAP Y   ND  T VLLA+   AGVRR V A SMVV
Sbjct  61   GRALRGVDAVCHQAAMVGLGKDFADAPEYVACNDLGTAVLLAETARAGVRRFVQAGSMVV  120

Query  120  YGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAAS  179
            YG+GRY+C  HG V P PR  ADL+ G FE RCP CG+ ++  LVDEDAP  PR++YA +
Sbjct  121  YGEGRYECRGHGVVRPGPRAAADLEAGRFEPRCPRCGDGLVPGLVDEDAPADPRNVYATT  180

Query  180  KTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFED  239
            K AQEH A AW+ ++GG+ V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+VFED
Sbjct  181  KLAQEHLAAAWARSTGGTAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVFED  240

Query  240  GGQMRDFVHVDDVAAANLAAVHLGEA-DRDGFTAVNVCSGRPISILQVATAICDARGGSM  298
            G Q RDFVHV DVA AN A +   E     G TA NV SG P ++ ++A A+    GG  
Sbjct  241  GAQRRDFVHVRDVARANAAVLAGVEGLPAGGHTAYNVGSGDPHTVGEMAAALAAEHGGP-  299

Query  299  SPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            +P +TG +R GDVRHI AD +R  R LG+R  V   +G+ EFA A  R
Sbjct  300  APVVTGEFRLGDVRHITADSSRLRRELGWRPEVGFEQGMAEFARAGQR  347


>gi|331699676|ref|YP_004335915.1| UDP-glucose 4-epimerase [Pseudonocardia dioxanivorans CB1190]
 gi|326954365|gb|AEA28062.1| UDP-glucose 4-epimerase [Pseudonocardia dioxanivorans CB1190]
Length=351

 Score =  351 bits (900),  Expect = 1e-94, Method: Compositional matrix adjust.
 Identities = 208/349 (60%), Positives = 238/349 (69%), Gaps = 7/349 (2%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHG---PNPVLPPGCQRVDVRDAS  57
            MRVL+TG AGFIGS V   L A GH  V +DALLP AHG   P         R DVRDA 
Sbjct  1    MRVLVTGGAGFIGSHVADLLAAQGHQPVVLDALLPQAHGAGVPEWTAAHEFVRGDVRDAE  60

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
             L  LL GVD VCHQAAMVG GV+  DAP Y  HND  T VLLA+M   GVRRLVLA SM
Sbjct  61   VLRRLLPGVDAVCHQAAMVGHGVDPYDAPDYAAHNDVGTAVLLAEMHRVGVRRLVLAGSM  120

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+GRYDC +HG V P PR  AD++ GVFE RCP CG  ++  LV EDAPL PRS YA
Sbjct  121  VVYGEGRYDCAEHGIVRPGPRALADIEAGVFEPRCPRCGRELVPGLVAEDAPLDPRSTYA  180

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            A+K AQEH A AW+  +G SV +LRYHNVYGP MP  TPY+GVA+IFRSA+E+G+ P+V 
Sbjct  181  ATKLAQEHLASAWARQTGASVWSLRYHNVYGPRMPFGTPYAGVASIFRSALERGEAPRVM  240

Query  238  EDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGS  297
            EDG Q RDFVHV DVAAANLAA+       DG  AVNVCSG P ++  +A  +  A GG 
Sbjct  241  EDGRQRRDFVHVTDVAAANLAAL---TTPADGVVAVNVCSGEPHTVGDLADELARAMGGP  297

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +P + G  R GDVRH+VADPARA   LGF A V   +G+  FA  PLR
Sbjct  298  -APQVVGGARPGDVRHVVADPARARDRLGFHAQVRFADGVAAFATDPLR  345


>gi|86739689|ref|YP_480089.1| NAD-dependent epimerase/dehydratase [Frankia sp. CcI3]
 gi|86566551|gb|ABD10360.1| NAD-dependent epimerase/dehydratase [Frankia sp. CcI3]
Length=347

 Score =  348 bits (893),  Expect = 8e-94, Method: Compositional matrix adjust.
 Identities = 199/349 (58%), Positives = 238/349 (69%), Gaps = 6/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV--DVRDASA  58
            MRVL+TG AGFIGS V  AL AAG +V  +DALLPA H   P +    + +  DV D   
Sbjct  1    MRVLVTGGAGFIGSHVVDALVAAGDEVRILDALLPAVHRTKPQVNNAAEMIVGDVTDRDQ  60

Query  59   LAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMV  118
            +A  L+G+D+VCHQAAMVG GV+  D PAY  +ND  T VLLA M  AGV RLVLASSMV
Sbjct  61   VAEALSGIDVVCHQAAMVGLGVDLDDLPAYATNNDLGTAVLLAAMARAGVGRLVLASSMV  120

Query  119  VYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAA  178
            VYG+G Y CP  GPV P PR+ A+LD G FE  CP C  P+   +V EDAPL PR+ YAA
Sbjct  121  VYGEGGYRCPTDGPVRPGPRQAAELDAGRFEPPCPRCHRPLAPIVVHEDAPLDPRNAYAA  180

Query  179  SKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFE  238
            +K AQEH A AW+  +GG+ VALRYHNVYGP MPRDTPY+GVA+IFRSA+E G+ P+VFE
Sbjct  181  TKVAQEHLAAAWAAETGGTAVALRYHNVYGPRMPRDTPYAGVASIFRSALEHGRAPRVFE  240

Query  239  DGGQMRDFVHVDDVAAANLAAVHLGEADRDG-FTAVNVCSGRPISILQVATAICDARGGS  297
            DG Q+RDFVHV DVA ANL A   G+    G    +N+ SG P ++  +A A+  A GG 
Sbjct  241  DGRQLRDFVHVHDVARANLLAS--GQPQAPGRLVPLNIGSGDPHTVGDMADALARAFGGP  298

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              P +TG  R GDVRHI A  ARA  +LG+R  VD  EG+R FA  PLR
Sbjct  299  -RPVVTGTSRVGDVRHIAASSARAGDLLGYRPRVDFAEGMRAFAHDPLR  346


>gi|159038332|ref|YP_001537585.1| NAD-dependent epimerase/dehydratase [Salinispora arenicola CNS-205]
 gi|157917167|gb|ABV98594.1| NAD-dependent epimerase/dehydratase [Salinispora arenicola CNS-205]
Length=370

 Score =  347 bits (891),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 199/349 (58%), Positives = 234/349 (68%), Gaps = 6/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPN-PVLPPGCQRV--DVRDAS  57
            MR+L+TG AGF+GS V     A GH+VVG+DALLP AHG   PV     Q V  DVRDA+
Sbjct  1    MRILVTGVAGFVGSHVADLAVADGHEVVGMDALLPQAHGGELPVWSRAHQPVVGDVRDAA  60

Query  58   ALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSM  117
             L  LL GVD VCHQAAMVG G++ +DAPAY  HND+ T VLLA M  AGVRRLVLASSM
Sbjct  61   LLDRLLPGVDAVCHQAAMVGHGLDPSDAPAYASHNDYGTAVLLAAMHRAGVRRLVLASSM  120

Query  118  VVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYA  177
            VVYG+G Y C  HG V P PRR  DL  G ++  CP C + +   LV EDAP+ PRS YA
Sbjct  121  VVYGEGAYRCSTHGSVRPTPRRPDDLAVGRYDPTCPHCHQALSPGLVPEDAPVEPRSTYA  180

Query  178  ASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVF  237
            ASK AQEH A AW+  +GG   ALRYHNVYGP MPRDTPY+GVA+IFRSA+  G+ P+V 
Sbjct  181  ASKLAQEHLAAAWARQAGGG-WALRYHNVYGPRMPRDTPYAGVASIFRSALAAGRAPRVL  239

Query  238  EDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGS  297
            EDG Q RDFVHV DVA ANL A+     D D    VN+CSG P ++  +A  +  A  G 
Sbjct  240  EDGRQRRDFVHVTDVARANLLALQTAPPDGD-LVPVNICSGEPRTVADLANTLAKAMDGP  298

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +P + G  R  DVRH+VADP RA  +LG+ A V   EG+  FA  PLR
Sbjct  299  -APVVVGGARGADVRHVVADPRRATNLLGYTARVGFAEGVAGFAHDPLR  346


>gi|345003429|ref|YP_004806283.1| NAD-dependent epimerase/dehydratase [Streptomyces sp. SirexAA-E]
 gi|344319055|gb|AEN13743.1| NAD-dependent epimerase/dehydratase [Streptomyces sp. SirexAA-E]
Length=356

 Score =  342 bits (877),  Expect = 5e-92, Method: Compositional matrix adjust.
 Identities = 199/353 (57%), Positives = 241/353 (69%), Gaps = 8/353 (2%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLP----PGCQRV--DVR  54
            MRVL+TG AGFIGS +  AL + GH+ V  DALLP A+G          PG + V  DVR
Sbjct  1    MRVLVTGGAGFIGSHIVRALASGGHEAVIFDALLPTAYGGEKPWSADCVPGVRTVIADVR  60

Query  55   DASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLA  114
            D  A+A  L+GVD VCHQAAMVG G + ADAP Y G ND  T VLLA M  AGVR LVLA
Sbjct  61   DREAVAAALSGVDAVCHQAAMVGLGKDFADAPEYVGCNDLGTAVLLAGMADAGVRDLVLA  120

Query  115  SSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRS  174
             SMVVYG+GRYDCP+HG V P PR  +DLD G FE RCP CG  +   LV E+A   PR+
Sbjct  121  GSMVVYGEGRYDCPRHGRVRPGPRAVSDLDAGRFEPRCPDCGSELTPGLVAEEAAADPRN  180

Query  175  LYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPP  234
            +YAA+K AQEH A +W+ A+GG  V+LRYHNVYGPGMPRDTPY+GVA++FRSA+ +G+ P
Sbjct  181  VYAATKLAQEHLAASWARATGGRAVSLRYHNVYGPGMPRDTPYAGVASLFRSALARGEAP  240

Query  235  KVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDG-FTAVNVCSGRPISILQVATAICDA  293
            +VFEDGGQ RDFVHV DVAAAN  A+        G F A N  SG+P +I ++A A+  A
Sbjct  241  RVFEDGGQRRDFVHVRDVAAANAVALAALRERGPGTFDAYNTGSGQPHTIGEMARALASA  300

Query  294  RGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             GG  +P +TG YR GDVRH+ AD  R    LG++   +   G+REFA + LR
Sbjct  301  HGGP-APVVTGEYRLGDVRHVTADSRRLRDELGWKPETEFVAGMREFATSALR  352


>gi|311743371|ref|ZP_07717178.1| NAD-dependent epimerase/dehydratase [Aeromicrobium marinum DSM 
15272]
 gi|311313439|gb|EFQ83349.1| NAD-dependent epimerase/dehydratase [Aeromicrobium marinum DSM 
15272]
Length=346

 Score =  342 bits (876),  Expect = 7e-92, Method: Compositional matrix adjust.
 Identities = 187/346 (55%), Positives = 222/346 (65%), Gaps = 2/346 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            M+VLLTGAAGFIG+ +       GHDV  +D  L  AHG      P   R+D+R +  L 
Sbjct  1    MKVLLTGAAGFIGTHIGRIAGERGHDVRRLDLYLEKAHGTGGERDPRVARLDLR-SDRLD  59

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
             ++A VD+VCHQAAMVG GV+A D P Y  HND  T  LLA M   G R LVLASSMVVY
Sbjct  60   EIVADVDVVCHQAAMVGNGVDAQDLPDYAEHNDAGTARLLAAMARVGARDLVLASSMVVY  119

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G GRY CP+HG V P  RR  DL  G ++ RCP C  P+ W+ +DE  P  PR+ YAASK
Sbjct  120  GDGRYTCPEHGDVPPATRREDDLSAGRYDPRCPVCAGPIEWRRIDESTPFLPRTSYAASK  179

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEHYA AW        +ALRYHNVYGPGMP DTPY+GVAAIFRS++ +G+ P+VFEDG
Sbjct  180  VAQEHYASAWCTLEDARAIALRYHNVYGPGMPADTPYAGVAAIFRSSIARGEAPRVFEDG  239

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q+RDFVHV D+A AN+ AV    A R G TA NV SG P +I ++A  +  A G    P
Sbjct  240  RQVRDFVHVHDIALANVLAVEQVSAHRGGLTAYNVASGHPTTIGEMARTLAAAAGAP-EP  298

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YR  DVRH+VA P  A   LGF A V P +GL   A  PLR
Sbjct  299  VVTGEYRRFDVRHVVASPDAARDSLGFSAEVRPEDGLAALATDPLR  344


>gi|291300413|ref|YP_003511691.1| NAD-dependent epimerase/dehydratase [Stackebrandtia nassauensis 
DSM 44728]
 gi|290569633|gb|ADD42598.1| NAD-dependent epimerase/dehydratase [Stackebrandtia nassauensis 
DSM 44728]
Length=352

 Score =  341 bits (875),  Expect = 8e-92, Method: Compositional matrix adjust.
 Identities = 195/349 (56%), Positives = 232/349 (67%), Gaps = 4/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLP-PGCQRVDVRDASAL  59
            MRVL+TG AGFIGSR+  ALR AGHDVV  D LL AAHGP+P    P     DVRD  A+
Sbjct  1    MRVLVTGGAGFIGSRIATALRQAGHDVVIADVLLAAAHGPHPRKDHPHMLCADVRDRGAM  60

Query  60   APLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVV  119
               L  VD+VCHQAAMVG G   ADA  Y   ND  T  LL+ M  AGVRRLVLA SMVV
Sbjct  61   RRALRHVDVVCHQAAMVGLGNGFADACDYVDCNDLGTAALLSAMADAGVRRLVLAGSMVV  120

Query  120  YGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAAS  179
            YG+G Y C +HG V P PR+  DLD G FE  CP CGE +   LV+E A + PR++YAA+
Sbjct  121  YGEGVYHCAEHGQVRPGPRQVGDLDAGRFEPPCPHCGEALSPGLVEETATIDPRNVYAAT  180

Query  180  KTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFED  239
            K AQE+ A AW+ A  G V++LRYHNVYGPGMPRDTPY+GVA+ FRSA+E G+PPKVFED
Sbjct  181  KIAQEYLASAWARACAGRVISLRYHNVYGPGMPRDTPYAGVASFFRSALENGEPPKVFED  240

Query  240  GGQMRDFVHVDDVAAANLAAVHLGEAD--RDGFTAVNVCSGRPISILQVATAICDARGGS  297
            G Q RDFVHV D+A+ANLAA+    A+         NV SG P ++ ++A  +    GG 
Sbjct  241  GAQRRDFVHVRDIASANLAALDAVYANIPEGTLRPYNVASGTPHTVGEMAAELAGFFGGP  300

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              P +TG YR GDVRHI A   R    L ++  VD  +G+ EFA APLR
Sbjct  301  -EPVVTGEYRLGDVRHITASTRRIRSELDWKPRVDFRKGVAEFAAAPLR  348


>gi|345009975|ref|YP_004812329.1| NAD-dependent epimerase/dehydratase [Streptomyces violaceusniger 
Tu 4113]
 gi|344036324|gb|AEM82049.1| NAD-dependent epimerase/dehydratase [Streptomyces violaceusniger 
Tu 4113]
Length=369

 Score =  338 bits (868),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 197/348 (57%), Positives = 233/348 (67%), Gaps = 3/348 (0%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TG AGFIGS +  AL   GH+ V +DALLPAAH   P +       DVRD  A+ 
Sbjct  20   MRVLVTGGAGFIGSHIVTALTEHGHEPVVLDALLPAAHPTPPTVDGEWIHADVRDREAVV  79

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              L GVD VCHQAAMVG G + ADAPAY G ND  T VLLA M   GVR LVLA SMVVY
Sbjct  80   AALRGVDAVCHQAAMVGLGKDFADAPAYVGCNDLGTAVLLAAMAERGVRELVLAGSMVVY  139

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+GRYDCP+HG V P PR  ADL  G F+ RCP CG  +    V+EDAP+ PR++YA +K
Sbjct  140  GEGRYDCPRHGRVRPGPRAEADLAAGRFDPRCPECGTSLRPGKVEEDAPVDPRNVYATTK  199

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+ + GG  V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P VFEDG
Sbjct  200  LAQEHLAAAWARSVGGRAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPMVFEDG  259

Query  241  GQMRDFVHVDDVAAANLAAVHLGE--ADRDGFTAVNVCSGRPISILQVATAICDARGGSM  298
            GQ RDFVHV DVAAAN+AA+            TA N  S  P ++ ++A A+  A GG  
Sbjct  260  GQRRDFVHVRDVAAANVAALEAAPEVVAPSTLTAYNTGSDDPHTVGEMAAALATAFGGP-  318

Query  299  SPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            +P +TG YR GDVRHI A   R    LG+RAA+   EG+  FA AP R
Sbjct  319  APVVTGGYRLGDVRHITASSRRIREALGWRAAISFTEGMTAFARAPQR  366


>gi|289770655|ref|ZP_06530033.1| epimerase [Streptomyces lividans TK24]
 gi|289700854|gb|EFD68283.1| epimerase [Streptomyces lividans TK24]
Length=337

 Score =  337 bits (864),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 194/346 (57%), Positives = 225/346 (66%), Gaps = 14/346 (4%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TG+AGFIGS V  ALR  GH+ VG D              PG    DVRD +ALA
Sbjct  4    MRVLVTGSAGFIGSHVVEALREHGHEPVGYDVRED----------PGA---DVRDPAALA  50

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              LAGVD VCHQAAMVG G   ADA  Y   ND  T VLLA    AGVRRLVLA SMVVY
Sbjct  51   RALAGVDAVCHQAAMVGLGNGFADAAEYVSRNDLGTAVLLAATAGAGVRRLVLAGSMVVY  110

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+GRY C +HG V P PR  ADLD G FE  CP CG  +   LV EDAP  PR++YA +K
Sbjct  111  GEGRYTCARHGVVRPGPRAVADLDAGRFEPTCPRCGADLAPGLVGEDAPADPRNVYATTK  170

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+  +G + V+LRYHNVYGP MPRDTPY+GVA+ FRSA+ +G+ P+VFEDG
Sbjct  171  LAQEHLAAAWARTTGATAVSLRYHNVYGPRMPRDTPYAGVASFFRSALARGEAPRVFEDG  230

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q RDFVHV DVAAAN+AA+          +A N  SG P ++ ++A A+  A GG   P
Sbjct  231  RQRRDFVHVRDVAAANVAALESARPPEGALSAYNTGSGEPHTVGEMAVALSAAHGGP-EP  289

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YR GDVRHI AD AR    LG+R  V   EG+REFA   LR
Sbjct  290  VVTGEYRLGDVRHITADSARLRTDLGWRPRVGFAEGMREFARDGLR  335


>gi|297560679|ref|YP_003679653.1| NAD-dependent epimerase/dehydratase [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
 gi|296845127|gb|ADH67147.1| NAD-dependent epimerase/dehydratase [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
Length=373

 Score =  337 bits (863),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 193/349 (56%), Positives = 227/349 (66%), Gaps = 4/349 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV-DVRDASAL  59
            MRVL+TG AGFIGSRV   LR AGH+ V +DA LP AH            V DVRD   +
Sbjct  1    MRVLVTGGAGFIGSRVAEELRLAGHEAVTLDAYLPQAHTGRDTEHRTVDVVGDVRDGEIV  60

Query  60   APLLAGVDLVCHQAAMVGAG-VNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMV  118
               L GVD VCHQAAMVG G  +  DAP Y   ND  T VLLA M   GVR +V+A SMV
Sbjct  61   ERALRGVDAVCHQAAMVGLGSADFLDAPDYVRCNDLGTAVLLAAMARTGVRDIVMAGSMV  120

Query  119  VYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAA  178
            VYG+GRY CP+HG V P PR  ADL  GVF+  CP CG P++  LV EDAP  PR++YA 
Sbjct  121  VYGEGRYTCPEHGDVRPGPRAEADLRAGVFDPPCPRCGAPLVPGLVGEDAPSDPRNVYAT  180

Query  179  SKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFE  238
            +K AQEH   AW+ + GG  V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+VFE
Sbjct  181  TKLAQEHLCAAWARSVGGRAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVFE  240

Query  239  DGGQMRDFVHVDDVAAANLAAVHLGEADRDG-FTAVNVCSGRPISILQVATAICDARGGS  297
            DG Q RDFVHV DVA AN+AA+        G  +A N  SG P +I ++A A+ DA GG 
Sbjct  241  DGRQRRDFVHVGDVARANVAALEAVAGRAPGELSAFNTGSGTPHTIGEMARALADAHGGP  300

Query  298  MSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
              P +TG YR GDVRHI A   R  R L +R  V   EG+ EFA A LR
Sbjct  301  -EPLVTGEYRLGDVRHITASSDRLRRELSWRPRVGFAEGMAEFARAELR  348


>gi|302554751|ref|ZP_07307093.1| epimerase [Streptomyces viridochromogenes DSM 40736]
 gi|302472369|gb|EFL35462.1| epimerase [Streptomyces viridochromogenes DSM 40736]
Length=333

 Score =  336 bits (861),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 193/346 (56%), Positives = 228/346 (66%), Gaps = 15/346 (4%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TG AGFIGS V  ALR  GH+ V  D              PG    DVRD +A+ 
Sbjct  1    MRVLVTGGAGFIGSHVVTALRERGHEAVVFDVRED----------PGA---DVRDPAAVR  47

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              L+G D VCHQAAMVG G   ADA  Y  HND  T VLLA M  AGVRRLVLA SMVVY
Sbjct  48   RALSGADAVCHQAAMVGLGDGVADAAEYVSHNDLGTAVLLAAMAEAGVRRLVLAGSMVVY  107

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+GRY+CP+HG V P PR  ADL  G FE  CP CG  ++  LV EDAP  PR++YA +K
Sbjct  108  GEGRYECPRHGVVRPGPRALADLRAGRFEPPCPACGADLLPGLVGEDAPTDPRNVYATTK  167

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+  +GGS V+LRYHNVYGPGMPRDTPY+GVA+ FRSA+ +G+ P+V+EDG
Sbjct  168  LAQEHLAAAWARCTGGSAVSLRYHNVYGPGMPRDTPYAGVASFFRSALARGEAPRVYEDG  227

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q RDFVHV DVA ANLAAV    +     TA N  SG P ++ ++A A+  A GG   P
Sbjct  228  RQRRDFVHVRDVAEANLAAVE-ASSPTGALTAYNTGSGDPHTVGEMARALAAAYGGP-EP  285

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG +R GDVRHI AD AR    LG++ AV   EG+ EFA A +R
Sbjct  286  VVTGEFRLGDVRHITADSARLRDGLGWKPAVGFEEGMAEFARAGMR  331


>gi|336176419|ref|YP_004581794.1| UDP-glucose 4-epimerase [Frankia symbiont of Datisca glomerata]
 gi|334857399|gb|AEH07873.1| UDP-glucose 4-epimerase [Frankia symbiont of Datisca glomerata]
Length=347

 Score =  336 bits (861),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 199/352 (57%), Positives = 238/352 (68%), Gaps = 12/352 (3%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRV--DVRDASA  58
            MR+L+TG AGFIGS V   L AAG  V  +DALLPA H   P +    + +  DV D   
Sbjct  1    MRILVTGGAGFIGSHVVDMLVAAGDSVRILDALLPAVHRSRPEVNAAAELIVADVTDRPQ  60

Query  59   LAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMV  118
            +   L GVD VCHQAAMVG GV+  D PAY  HND  T VLLA M   GVRRLVLASSMV
Sbjct  61   VEAALDGVDAVCHQAAMVGLGVDLDDLPAYAAHNDLGTAVLLAAMARRGVRRLVLASSMV  120

Query  119  VYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAA  178
            VYG+G Y CP  GPV P PR  A+L  G FE  CP CG P+   LV EDAPL P+S+YAA
Sbjct  121  VYGEGGYRCPADGPVRPGPRLPAELAAGRFEPPCPSCGRPLEPTLVAEDAPLEPKSVYAA  180

Query  179  SKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFE  238
            +K AQEH A AW+ A+GGSV+ALRYHNVYGP MPRDTPY+GVA+IFRSA+E+G+PP+VFE
Sbjct  181  TKVAQEHLAAAWATATGGSVLALRYHNVYGPRMPRDTPYAGVASIFRSALERGEPPRVFE  240

Query  239  DGGQMRDFVHVDDVAAANLAAVH----LGEADRDGFTAVNVCSGRPISILQVATAICDAR  294
            DGGQ+RDFVHV DVA ANL A+     LGE        +N+ SG P S+  +A+ +    
Sbjct  241  DGGQLRDFVHVHDVAQANLHALRHPGVLGE-----LVPLNIGSGEPHSVGDMASVLARVF  295

Query  295  GGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            GG+ +P +TG YR+GDVRH+ A  A A   LG++  V   EG+  FA  PLR
Sbjct  296  GGA-APVVTGLYRAGDVRHVTASSALARGFLGYQPRVTFDEGVNAFARDPLR  346


>gi|328886562|emb|CCA59801.1| NAD-dependent epimerase or dehydratase family protein [Streptomyces 
venezuelae ATCC 10712]
Length=357

 Score =  335 bits (860),  Expect = 6e-90, Method: Compositional matrix adjust.
 Identities = 191/352 (55%), Positives = 233/352 (67%), Gaps = 7/352 (1%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQ-----RVDVRD  55
            MRVL+TG AGFIGS +  ALR AGH+ V +DALLP+AH   P              DVRD
Sbjct  1    MRVLVTGGAGFIGSHIVTALREAGHEPVVLDALLPSAHPTAPAPGAAAPPAEFVHADVRD  60

Query  56   ASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLAS  115
            A ++A +L GVD VCHQAAMVG G + ADAP Y   ND  T VLLA M   GVRRLVLA 
Sbjct  61   AWSVAAVLRGVDAVCHQAAMVGLGRDFADAPDYVSCNDLGTAVLLAAMAETGVRRLVLAG  120

Query  116  SMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSL  175
            SMVVYG+GRYDC +HGPV P  RR  DL  G+FE RCP CG  +   LV ED P  PR++
Sbjct  121  SMVVYGEGRYDCLRHGPVRPGARRPEDLAAGLFEPRCPDCGSALTPGLVGEDTPPDPRNV  180

Query  176  YAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPK  235
            YA++K  QEH A AW+ +  G+ ++LRYHNVYGPGMPRDTPY+GVA+ FRSA+ + + P+
Sbjct  181  YASTKLTQEHLAAAWARSVDGTALSLRYHNVYGPGMPRDTPYAGVASFFRSALARSEAPR  240

Query  236  VFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDG-FTAVNVCSGRPISILQVATAICDAR  294
            VFEDGGQ RDFVHV+DVAAAN+  +        G  TA N  SG P ++ ++ATA+  A 
Sbjct  241  VFEDGGQRRDFVHVEDVAAANVLGLEAAPGLPPGTLTAYNTGSGDPHTVGEMATALARAH  300

Query  295  GGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
            GG  +P +TG +R GDVRHI AD  R    LG+   +   EG+  FA A  R
Sbjct  301  GGP-APVVTGEFRLGDVRHITADSTRLRHDLGWHPRITFTEGMTAFAHAAQR  351


>gi|21222151|ref|NP_627930.1| epimerase [Streptomyces coelicolor A3(2)]
 gi|7211006|emb|CAB76986.1| putative epimerase [Streptomyces coelicolor A3(2)]
Length=334

 Score =  334 bits (856),  Expect = 1e-89, Method: Compositional matrix adjust.
 Identities = 193/346 (56%), Positives = 224/346 (65%), Gaps = 14/346 (4%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TG+AGFIGS V  ALR  GH+ VG D              PG    DVRD +ALA
Sbjct  1    MRVLVTGSAGFIGSHVVEALREHGHEPVGYDVRED----------PGA---DVRDPAALA  47

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              LAGVD VCHQAAMVG G   ADA  Y   ND  T VLLA    AGVRRLVLA SMVVY
Sbjct  48   RALAGVDAVCHQAAMVGLGNGFADAAEYVSRNDLGTAVLLAATAGAGVRRLVLAGSMVVY  107

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+GRY C +HG V P PR  ADLD G FE  CP CG  +   LV EDAP  PR++YA +K
Sbjct  108  GEGRYTCARHGVVRPGPRAVADLDAGRFEPTCPRCGADLAPGLVGEDAPADPRNVYATTK  167

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+  +G + V+LRYHNVYGP MPRDTPY+GVA+ FRSA+ +G+ P+VFEDG
Sbjct  168  LAQEHLAAAWARTTGATAVSLRYHNVYGPRMPRDTPYAGVASFFRSALARGEAPRVFEDG  227

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q RDFVHV DVAAAN+AA+          +A N  SG P ++ ++A A+  A GG   P
Sbjct  228  RQRRDFVHVRDVAAANVAALESARPPEGALSAYNTGSGEPHTVGEMAVALSAAHGGP-EP  286

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR  346
             +TG YR GDVRHI AD AR    L +R  V   EG+REFA   LR
Sbjct  287  VVTGEYRLGDVRHITADSARLRTDLDWRPRVGFAEGMREFARDGLR  332


>gi|329937260|ref|ZP_08286859.1| epimerase [Streptomyces griseoaurantiacus M045]
 gi|329303541|gb|EGG47427.1| epimerase [Streptomyces griseoaurantiacus M045]
Length=330

 Score =  330 bits (847),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 190/341 (56%), Positives = 221/341 (65%), Gaps = 16/341 (4%)

Query  1    MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALA  60
            MRVL+TG+AGFIGS V  AL A GH+ V +D                    DVRD   +A
Sbjct  4    MRVLVTGSAGFIGSHVVEALAARGHESVALDVREDGG--------------DVRDPEVVA  49

Query  61   PLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVY  120
              L GVD VCHQAAMVG G   ADAP Y   ND  T VLLA M  AGVRRLVLA SMVVY
Sbjct  50   DRLRGVDAVCHQAAMVGLGTGFADAPEYVSRNDLGTAVLLAAMAEAGVRRLVLAGSMVVY  109

Query  121  GQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASK  180
            G+G Y C +HG V P PR  ADLD G FE  CP CG  +   LV EDAP  PR++YA +K
Sbjct  110  GEGAYACSRHGAVRPGPRTVADLDAGRFEPPCPRCGAALSPGLVGEDAPADPRNVYATTK  169

Query  181  TAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDG  240
             AQEH A AW+ ++GGS V+LRYHNVYGP MPRDTPY+GVA+ FRS++ +G+ P+VFEDG
Sbjct  170  LAQEHLAAAWARSTGGSAVSLRYHNVYGPRMPRDTPYAGVASFFRSSLARGEAPRVFEDG  229

Query  241  GQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSP  300
             Q RDFVHV DVAAAN+ A+   EA     TA N  SG P +I  +A A+  A GG   P
Sbjct  230  RQRRDFVHVRDVAAANVTALE-AEAAPGALTAYNTGSGTPRTIADLAEALATACGGP-RP  287

Query  301  AITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFA  341
             +TG YR GDVRHI AD AR    LG++  V   EG+REFA
Sbjct  288  TVTGEYRLGDVRHITADSARLRADLGWKPEVAFEEGVREFA  328



Lambda     K      H
   0.322    0.138    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 636071322808




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40