BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0541c Length=449 Score E Sequences producing significant alignments: (Bits) Value gi|15607681|ref|NP_215055.1| integral membrane protein [Mycobact... 858 0.0 gi|31791723|ref|NP_854216.1| integral membrane protein [Mycobact... 857 0.0 gi|254549496|ref|ZP_05139943.1| hypothetical protein Mtube_03373... 855 0.0 gi|298524029|ref|ZP_07011438.1| conserved hypothetical protein [... 728 0.0 gi|298524023|ref|ZP_07011432.1| conserved hypothetical protein [... 709 0.0 gi|183980908|ref|YP_001849199.1| hypothetical protein MMAR_0887 ... 659 0.0 gi|118616444|ref|YP_904776.1| hypothetical protein MUL_0640 [Myc... 652 0.0 gi|240169221|ref|ZP_04747880.1| hypothetical protein MkanA1_0790... 639 0.0 gi|342858950|ref|ZP_08715604.1| hypothetical protein MCOL_08738 ... 588 7e-166 gi|296168278|ref|ZP_06850227.1| integral membrane protein [Mycob... 575 5e-162 gi|41410135|ref|NP_962971.1| hypothetical protein MAP4037c [Myco... 568 9e-160 gi|254777036|ref|ZP_05218552.1| integral membrane protein [Mycob... 565 7e-159 gi|118463924|ref|YP_883732.1| integral membrane protein [Mycobac... 564 1e-158 gi|126433320|ref|YP_001069011.1| hypothetical protein Mjls_0709 ... 541 9e-152 gi|108797694|ref|YP_637891.1| hypothetical protein Mmcs_0715 [My... 540 1e-151 gi|15839937|ref|NP_334974.1| hypothetical protein MT0566 [Mycoba... 528 1e-147 gi|120401906|ref|YP_951735.1| putative integral membrane protein... 503 2e-140 gi|118473533|ref|YP_885402.1| integral membrane protein [Mycobac... 494 1e-137 gi|111021239|ref|YP_704211.1| hypothetical protein RHA1_ro04262 ... 467 2e-129 gi|289744253|ref|ZP_06503631.1| integral membrane protein [Mycob... 442 5e-122 gi|289441926|ref|ZP_06431670.1| probable conserved integral memb... 435 7e-120 gi|226363585|ref|YP_002781367.1| hypothetical protein ROP_41750 ... 428 9e-118 gi|289744254|ref|ZP_06503632.1| integral membrane protein [Mycob... 381 1e-103 gi|291453188|ref|ZP_06592578.1| integral membrane protein [Strep... 352 7e-95 gi|254822009|ref|ZP_05227010.1| integral membrane protein [Mycob... 331 1e-88 gi|182440492|ref|YP_001828211.1| hypothetical protein SGR_6699 [... 328 1e-87 gi|326781162|ref|ZP_08240427.1| hypothetical protein SACT1_7053 ... 321 1e-85 gi|302530365|ref|ZP_07282707.1| hypothetical protein SSMG_06747 ... 315 1e-83 gi|291300407|ref|YP_003511685.1| hypothetical protein Snas_2917 ... 312 6e-83 gi|329937269|ref|ZP_08286868.1| integral membrane protein [Strep... 311 1e-82 gi|320012495|gb|ADW07345.1| hypothetical protein Sfla_5959 [Stre... 306 6e-81 gi|300790131|ref|YP_003770422.1| hypothetical protein AMED_8323 ... 294 2e-77 gi|345009966|ref|YP_004812320.1| hypothetical protein Strvi_2316... 291 2e-76 gi|297155367|gb|ADI05079.1| hypothetical protein SBI_01958 [Stre... 285 1e-74 gi|302554744|ref|ZP_07307086.1| integral membrane protein [Strep... 284 3e-74 gi|345003433|ref|YP_004806287.1| hypothetical protein SACTE_5963... 273 7e-71 gi|159038329|ref|YP_001537582.1| integral membrane protein [Sali... 265 1e-68 gi|290955003|ref|YP_003486185.1| protein [Streptomyces scabiei 8... 262 8e-68 gi|134099881|ref|YP_001105542.1| integral membrane protein [Sacc... 262 1e-67 gi|21222159|ref|NP_627938.1| integral membrane protein [Streptom... 261 2e-67 gi|295838765|ref|ZP_06825698.1| integral membrane protein [Strep... 259 8e-67 gi|302868411|ref|YP_003837048.1| integral membrane protein [Micr... 249 8e-64 gi|29831112|ref|NP_825746.1| hypothetical protein SAV_4569 [Stre... 246 7e-63 gi|254822075|ref|ZP_05227076.1| integral membrane protein [Mycob... 243 3e-62 gi|326328829|ref|ZP_08195165.1| putative membrane protein [Nocar... 239 6e-61 gi|88856675|ref|ZP_01131331.1| putative integral membrane protei... 236 6e-60 gi|333026935|ref|ZP_08454999.1| putative integral membrane prote... 220 4e-55 gi|318061573|ref|ZP_07980294.1| integral membrane protein [Strep... 220 5e-55 gi|302519218|ref|ZP_07271560.1| integral membrane protein [Strep... 219 8e-55 gi|302541882|ref|ZP_07294224.1| integral membrane protein [Strep... 217 3e-54 >gi|15607681|ref|NP_215055.1| integral membrane protein [Mycobacterium tuberculosis H37Rv] gi|148660310|ref|YP_001281833.1| putative integral membrane protein [Mycobacterium tuberculosis H37Ra] gi|148821743|ref|YP_001286497.1| integral membrane protein [Mycobacterium tuberculosis F11] 64 more sequence titles Length=449 Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 449/449 (100%), Gaps = 0/449 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW Sbjct 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL Sbjct 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG Sbjct 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA Sbjct 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 Query 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LLPPRSHRLWLAVNAAGALLLNSIIFTNW Sbjct 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 >gi|31791723|ref|NP_854216.1| integral membrane protein [Mycobacterium bovis AF2122/97] gi|121636459|ref|YP_976682.1| putative integral membrane protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988931|ref|YP_002643618.1| putative integral membrane protein [Mycobacterium bovis BCG str. Tokyo 172] gi|31617309|emb|CAD93417.1| PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [Mycobacterium bovis AF2122/97] gi|121492106|emb|CAL70570.1| Probable conserved integral membrane protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772044|dbj|BAH24850.1| putative integral membrane protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341600475|emb|CCC63145.1| probable conserved integral membrane protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=449 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/449 (99%), Positives = 449/449 (100%), Gaps = 0/449 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIW+AVSADGYFAGVAAW Sbjct 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWVAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL Sbjct 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG Sbjct 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA Sbjct 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 Query 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LLPPRSHRLWLAVNAAGALLLNSIIFTNW Sbjct 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 >gi|254549496|ref|ZP_05139943.1| hypothetical protein Mtube_03373 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=449 Score = 855 bits (2209), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/449 (99%), Positives = 448/449 (99%), Gaps = 0/449 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 R EYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RHEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW Sbjct 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL Sbjct 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRAL 300 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG Sbjct 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA Sbjct 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 Query 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LLPPRSHRLWLAVNAAGALLLNSIIFTNW Sbjct 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 >gi|298524029|ref|ZP_07011438.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298493823|gb|EFI29117.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=392 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/382 (99%), Positives = 381/382 (99%), Gaps = 0/382 (0%) Query 68 LTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQ 127 TAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQ Sbjct 11 FTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQ 70 Query 128 VPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCL 187 VPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCL Sbjct 71 VPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCL 130 Query 188 LVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAV 247 LVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAV Sbjct 131 LVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAV 190 Query 248 AVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAA 307 AVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAA Sbjct 191 AVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAA 250 Query 308 LVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSR 367 LVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSR Sbjct 251 LVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSR 310 Query 368 VFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSH 427 VFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSH Sbjct 311 VFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSH 370 Query 428 RLWLAVNAAGALLLNSIIFTNW 449 RLWLAVNAAGALLLNSIIFTNW Sbjct 371 RLWLAVNAAGALLLNSIIFTNW 392 >gi|298524023|ref|ZP_07011432.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298493817|gb|EFI29111.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=370 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/370 (99%), Positives = 370/370 (100%), Gaps = 0/370 (0%) Query 80 VAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLR 139 +AHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLR Sbjct 1 MAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLR 60 Query 140 TFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLI 199 TFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLI Sbjct 61 TFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLI 120 Query 200 AVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALV 259 AVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALV Sbjct 121 AVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALV 180 Query 260 AAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGF 319 AAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGF Sbjct 181 AAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGF 240 Query 320 SWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSG 379 SWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSG Sbjct 241 SWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSG 300 Query 380 CHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGAL 439 CHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGAL Sbjct 301 CHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGAL 360 Query 440 LLNSIIFTNW 449 LLNSIIFTNW Sbjct 361 LLNSIIFTNW 370 >gi|183980908|ref|YP_001849199.1| hypothetical protein MMAR_0887 [Mycobacterium marinum M] gi|183174234|gb|ACC39344.1| conserved hypothetical membrane protein [Mycobacterium marinum M] Length=450 Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/450 (78%), Positives = 388/450 (87%), Gaps = 1/450 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RI RRE AV +G VLV AAFVLPRL+LG+KPR DIGLERFA+RAGAAPIFGYWD H Sbjct 1 MRIARRETAAVTVGVVLVAAAFVLPRLDLGVKPRRDIGLERFASRAGAAPIFGYWDIHAS 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGT A+L A+AV+ WGP VA +L WRVL L+TWATA WAFSLAMIDG++RGFAGRLTT Sbjct 61 WGTIAAILLALAVLVWGPRVARKLSWRVLPLATWATACGWAFSLAMIDGFERGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 +DEYL +V G+ DIP LRTF SRI+D+QPNSW THVSGHPPGALLTFVWLDRIGL GG Sbjct 121 KDEYLSEVGGVTDIPVMLRTFASRIVDYQPNSWTTHVSGHPPGALLTFVWLDRIGLGGGA 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAG +CLLVGSSAAAA++IAV LA E +ARR APFVA+APTAIWIAVSADGYFAGV AW Sbjct 181 WAGFLCLLVGSSAAAAMVIAVGALAGEHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAAD-WRPVLRA 299 GI LLA+AVHG +RF AL AAGAGL+LGW +FL+YGL L+ LP +AVLA+A+ WR L+A Sbjct 241 GITLLAIAVHGGSRFRALWAAGAGLVLGWAIFLSYGLALMGLPALAVLASANHWRTALKA 300 Query 300 LGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGL 359 L PAVLAAL VA++FAVAGF WFDGYTLVQQRYWQGIA DRPF YWSWANLACVVCAIGL Sbjct 301 LWPAVLAALGVALAFAVAGFWWFDGYTLVQQRYWQGIAHDRPFQYWSWANLACVVCAIGL 360 Query 360 GSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAP 419 GSVAG+SRV D AAI RRSG HLLLL ++AAI +ADLSMLSKAETERIWLPFT+WLT AP Sbjct 361 GSVAGISRVVDAAAIRRRSGLHLLLLGMVAAILVADLSMLSKAETERIWLPFTVWLTTAP 420 Query 420 ALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ALL PRS RLWLAVNAAGAL +NSIIFTNW Sbjct 421 ALLRPRSDRLWLAVNAAGALAVNSIIFTNW 450 >gi|118616444|ref|YP_904776.1| hypothetical protein MUL_0640 [Mycobacterium ulcerans Agy99] gi|118568554|gb|ABL03305.1| conserved hypothetical membrane protein [Mycobacterium ulcerans Agy99] Length=450 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/450 (77%), Positives = 386/450 (86%), Gaps = 1/450 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RI RRE AV +G VLV AAFVLPRL+LG+KPR DIGLERFA+RAGAAPIFGYWD H Sbjct 1 MRIARRETAAVTVGVVLVAAAFVLPRLDLGVKPRRDIGLERFASRAGAAPIFGYWDIHAS 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGT A+L A+AV+ WGP VA +L WRVL L+TWATA W FSLAMIDG++RGFAGRLTT Sbjct 61 WGTIAAILLALAVLVWGPRVARKLSWRVLPLATWATACGWPFSLAMIDGFERGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 +DEYL +V G+ DIP LRTF SRI+D+QPNSW THVSGHPPGALLTFVWLDRIGL GG Sbjct 121 KDEYLSEVGGVTDIPVMLRTFASRIVDYQPNSWTTHVSGHPPGALLTFVWLDRIGLGGGA 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAG +CLLVGSSAAAA++IAV LA + +ARR APFVA+APTAIWIAVSADGYFAGV AW Sbjct 181 WAGFLCLLVGSSAAAAMVIAVGALAGKHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAAD-WRPVLRA 299 GI LLA+AVHG +RF AL AAGAGL+LGW +FL+YGL L+ LP +AVLA+A+ WR L+A Sbjct 241 GITLLAIAVHGGSRFRALWAAGAGLVLGWAIFLSYGLALMGLPALAVLASANHWRTALKA 300 Query 300 LGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGL 359 L PAVLAAL VA++FAVAGF WFDGYTLVQQRYWQGIA DRPF YWSWANLACVVCAIGL Sbjct 301 LWPAVLAALGVALAFAVAGFWWFDGYTLVQQRYWQGIAHDRPFQYWSWANLACVVCAIGL 360 Query 360 GSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAP 419 GSVAG+SRV D AAI RRSG HL LL ++AAI +ADLSMLSKAETERIWLPFT+WLT AP Sbjct 361 GSVAGISRVVDAAAIRRRSGLHLPLLGMVAAILVADLSMLSKAETERIWLPFTVWLTTAP 420 Query 420 ALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ALL PRS RLWLAVNAAGAL +NSIIFTNW Sbjct 421 ALLRPRSDRLWLAVNAAGALAVNSIIFTNW 450 >gi|240169221|ref|ZP_04747880.1| hypothetical protein MkanA1_07904 [Mycobacterium kansasii ATCC 12478] Length=450 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/450 (82%), Positives = 400/450 (89%), Gaps = 1/450 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RI RRE AVA+G VLV AAFVLPR+NLG+KPR DIGLERFA+RAGAAPIFGYWD H Sbjct 1 MRIARRETSAVAVGVVLVAAAFVLPRMNLGVKPRRDIGLERFASRAGAAPIFGYWDVHAS 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGT A++ A+AVVAWGPVV RL WR+LTL +WAT+ AWAFSLAMIDGWQ+GFAGRLTT Sbjct 61 WGTWAAIVIALAVVAWGPVVTQRLSWRLLTLGSWATSCAWAFSLAMIDGWQQGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 +DEYL +VPGI DIPAT+RTF SRI+DFQPNSW THVSGHPPGALLTFVWLDR+GL GG Sbjct 121 KDEYLSEVPGIRDIPATVRTFASRIVDFQPNSWTTHVSGHPPGALLTFVWLDRLGLHGGA 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGL+CLLVGSSAAAAV++AVR LA E ARR APF+A+APTAIW+AVSADGYFAGVAAW Sbjct 181 WAGLLCLLVGSSAAAAVVVAVRALAGEHTARRAAPFLALAPTAIWVAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL-AAADWRPVLRA 299 GIALLAVAVH TRFP LVAAGAGLLLGWGVFL+YGL+L+ LP +AVL ++ DWR LRA Sbjct 241 GIALLAVAVHAGTRFPGLVAAGAGLLLGWGVFLSYGLMLMGLPALAVLVSSKDWRAGLRA 300 Query 300 LGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGL 359 LGPAV+AA VAV+FAVAGFSWF+GYTLVQQRYWQGIA DRPF YWSWANLACVVCAIGL Sbjct 301 LGPAVVAAAAVAVAFAVAGFSWFEGYTLVQQRYWQGIAHDRPFQYWSWANLACVVCAIGL 360 Query 360 GSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAP 419 GSVAG+SRVFDR AI RRSG HLLLL LAAI ADLSMLSKAETERIWLPFTIWLTAAP Sbjct 361 GSVAGVSRVFDREAIRRRSGFHLLLLGALAAIVCADLSMLSKAETERIWLPFTIWLTAAP 420 Query 420 ALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ALLP RS RLWLAVNAAGALLLNSIIFTNW Sbjct 421 ALLPERSARLWLAVNAAGALLLNSIIFTNW 450 >gi|342858950|ref|ZP_08715604.1| hypothetical protein MCOL_08738 [Mycobacterium colombiense CECT 3035] gi|342133191|gb|EGT86394.1| hypothetical protein MCOL_08738 [Mycobacterium colombiense CECT 3035] Length=453 Score = 588 bits (1516), Expect = 7e-166, Method: Compositional matrix adjust. Identities = 337/434 (78%), Positives = 365/434 (85%), Gaps = 8/434 (1%) Query 24 LPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHR 83 LPR+N+G++PR D+G E+FAT AGAAPIFG W H GWGT PA+ A+AVVAWGP +A R Sbjct 20 LPRMNIGVRPRLDVGAEKFATHAGAAPIFGEWLIHAGWGTGPAIALAIAVVAWGPPLAQR 79 Query 84 LPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTS 143 L WR LTL +WATA WAF+LAMIDGWQRGFAGRLTTRDEYL QVPGI DI ATLRTF Sbjct 80 LSWRALTLGSWATACGWAFALAMIDGWQRGFAGRLTTRDEYLSQVPGITDIGATLRTFAG 139 Query 144 RILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRV 203 RI+D+QPNSW THVSGHPPGALLTFVWLDR+GL GG WAGL+CLL GSSAAAAV+IAVR Sbjct 140 RIVDYQPNSWTTHVSGHPPGALLTFVWLDRLGLHGGAWAGLLCLLAGSSAAAAVVIAVRA 199 Query 204 LASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGA 263 LA E ARR APFVA+APTAIW+AVSADGYFAGVAAWGIALLAVAVH RFPAL AAGA Sbjct 200 LADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHRPVRFPALTAAGA 259 Query 264 GLLLGWGVFLNYGLVLIVLPGMAVLAAAD--------WRPVLRALGPAVLAALVVAVSFA 315 GLLLGWGVF NYGL+L+ LP +AVL A WR +LRALGPA LAA+ VA +FA Sbjct 260 GLLLGWGVFCNYGLMLMGLPALAVLVGAQQPASGLAHWRAILRALGPAALAAIAVAAAFA 319 Query 316 VAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAIS 375 VAGF WFDGYTLVQQRYWQGIAKDRPF YWSWANLACVVCAIGLG VAG+SRVFD AI Sbjct 320 VAGFFWFDGYTLVQQRYWQGIAKDRPFQYWSWANLACVVCAIGLGGVAGISRVFDWPAIR 379 Query 376 RRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNA 435 RRSG HLLLL VLAAI ADLSMLSKAE ERIWLPFTIWLTAA ALLP RSHR+WLA+NA Sbjct 380 RRSGFHLLLLGVLAAIVFADLSMLSKAEVERIWLPFTIWLTAAAALLPVRSHRIWLALNA 439 Query 436 AGALLLNSIIFTNW 449 GAL LN+II TNW Sbjct 440 VGALALNTIILTNW 453 >gi|296168278|ref|ZP_06850227.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896797|gb|EFG76429.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=448 Score = 575 bits (1482), Expect = 5e-162, Method: Compositional matrix adjust. Identities = 357/448 (80%), Positives = 391/448 (88%), Gaps = 1/448 (0%) Query 3 IGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWG 62 + RRE LAVA G VLVGAAFVLPRL+LG++PR+D+G ERF T AGAAPIFG W+ H WG Sbjct 1 MARREWLAVAAGAVLVGAAFVLPRLHLGVRPRTDVGEERFGTHAGAAPIFGAWEIHASWG 60 Query 63 TAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRD 122 T PA+ A+A V WG ++A RL WRVLTL TWATA WAF+LAMIDGWQRGFAGRLTT+D Sbjct 61 TGPAIAIAIAAVVWGSILAQRLAWRVLTLGTWATACGWAFALAMIDGWQRGFAGRLTTKD 120 Query 123 EYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWA 182 EYL +VPG+ DIPAT+RTF RI+D+QP+SW THVSGHPPGALLTFVWLDRIGL GG WA Sbjct 121 EYLSEVPGVTDIPATVRTFAGRIVDYQPSSWTTHVSGHPPGALLTFVWLDRIGLHGGAWA 180 Query 183 GLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGI 242 GL+CLL GSSAAAAVLIAVR LA EQ ARR APFVAVAPTAIW+AVSADGYFAGVAAWGI Sbjct 181 GLLCLLAGSSAAAAVLIAVRALADEQTARRAAPFVAVAPTAIWVAVSADGYFAGVAAWGI 240 Query 243 ALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLA-AADWRPVLRALG 301 ALLAVAVH RFPAL AA AGLLLGWGVF NYGL+L+ LP +AVLA AA WR LRALG Sbjct 241 ALLAVAVHRGVRFPALTAAAAGLLLGWGVFCNYGLMLMGLPAVAVLASAAGWRTALRALG 300 Query 302 PAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGS 361 PA LAA+ VA +FAVAGF WFDGYTLVQQRYWQGIAK+RPF YWSWANLACVVCAIGLGS Sbjct 301 PAALAAVAVASAFAVAGFYWFDGYTLVQQRYWQGIAKNRPFQYWSWANLACVVCAIGLGS 360 Query 362 VAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPAL 421 VAG+SRVFDRAA+ RRSG HL+LLAVLAAIA ADLSMLSKAE ERIWLPFT+WLTAAPAL Sbjct 361 VAGVSRVFDRAAVRRRSGFHLVLLAVLAAIACADLSMLSKAEVERIWLPFTVWLTAAPAL 420 Query 422 LPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LP RSHR+WLA+NAAGALLLN+II TNW Sbjct 421 LPVRSHRVWLALNAAGALLLNTIIVTNW 448 >gi|41410135|ref|NP_962971.1| hypothetical protein MAP4037c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398968|gb|AAS06587.1| hypothetical protein MAP_4037c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460486|gb|EGO39381.1| hypothetical protein MAPs_40030 [Mycobacterium avium subsp. paratuberculosis S397] Length=458 Score = 568 bits (1463), Expect = 9e-160, Method: Compositional matrix adjust. Identities = 339/434 (79%), Positives = 366/434 (85%), Gaps = 9/434 (2%) Query 25 PRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRL 84 PRLNLG++ R D+G ERFAT AGAAPIFG W H GWGT PAV A AVVAWGPV+A RL Sbjct 25 PRLNLGVRQRLDVGPERFATHAGAAPIFGEWLIHAGWGTGPAVALAAAVVAWGPVLAQRL 84 Query 85 PWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSR 144 W LTL +WA AA WAF+LAMIDGWQRGFAGRLTTRDEYLW+VPGI DI A +RTF+SR Sbjct 85 SWWALTLGSWAVAAGWAFALAMIDGWQRGFAGRLTTRDEYLWEVPGIHDIAAAVRTFSSR 144 Query 145 ILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVL 204 I+D+QP+SW THVSGHPPGALLTFVWLDR+GL GGGWAGL+CLL GSSAAAAVLI VR L Sbjct 145 IVDYQPHSWTTHVSGHPPGALLTFVWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVRAL 204 Query 205 ASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAG 264 A E ARR APFVA+APTAIW+AVSADGYFAGVAAWGIALLAVAVH RFPAL AAGAG Sbjct 205 ADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHRPVRFPALTAAGAG 264 Query 265 LLLGWGVFLNYGLVLIVLPGMAVLAA---------ADWRPVLRALGPAVLAALVVAVSFA 315 LLLGWGVF NYGL+L+ LP AVLAA WR VLRALGPA L A+ VAV+FA Sbjct 265 LLLGWGVFCNYGLMLMGLPAAAVLAAAPRLPRDGRTQWRAVLRALGPAALGAIAVAVAFA 324 Query 316 VAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAIS 375 VAGF WFDGYTLVQQRYWQGIAKDRPF YWSWANLACVVCAIGLG VAG+ RVFDRAAI Sbjct 325 VAGFYWFDGYTLVQQRYWQGIAKDRPFQYWSWANLACVVCAIGLGGVAGVGRVFDRAAIR 384 Query 376 RRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNA 435 RRSG LLLLAVLAAIA ADLSMLSKAE ERIWLPFTIWLTAA ALLP R+HR+WLA+NA Sbjct 385 RRSGFPLLLLAVLAAIACADLSMLSKAEVERIWLPFTIWLTAAAALLPVRTHRIWLALNA 444 Query 436 AGALLLNSIIFTNW 449 GAL +N+II T+W Sbjct 445 VGALAVNTIILTHW 458 >gi|254777036|ref|ZP_05218552.1| integral membrane protein [Mycobacterium avium subsp. avium ATCC 25291] Length=450 Score = 565 bits (1455), Expect = 7e-159, Method: Compositional matrix adjust. Identities = 339/434 (79%), Positives = 367/434 (85%), Gaps = 9/434 (2%) Query 25 PRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRL 84 PRLNLG++PR D+G ERFAT AGAAPIFG W H GWGT PAV A AVVAWGPV+A RL Sbjct 17 PRLNLGVRPRLDVGPERFATHAGAAPIFGEWLIHAGWGTGPAVALAAAVVAWGPVLAQRL 76 Query 85 PWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSR 144 WR LTL +WA AA WAF+LAMIDGWQRGFAGRLTTRDEYLW+VP + DI A +RTF+SR Sbjct 77 SWRALTLGSWAVAAGWAFALAMIDGWQRGFAGRLTTRDEYLWEVPRVTDIAAAVRTFSSR 136 Query 145 ILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVL 204 I+D+QP+SW THVSGHPPGALLTFVWLDR+GL GGGWAGL+CLL GSSAAAAVLI VR L Sbjct 137 IVDYQPHSWTTHVSGHPPGALLTFVWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVRAL 196 Query 205 ASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAG 264 A E ARR APFVA+APTAIW+AVSADGYFAGVAAWGIALLAVAVH RFPAL AAGAG Sbjct 197 ADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHRPVRFPALTAAGAG 256 Query 265 LLLGWGVFLNYGLVLIVLPGMAVLAA---------ADWRPVLRALGPAVLAALVVAVSFA 315 LLLGWGVF NYGL+L+ LP AVLAA WR VLRALGPA LAA+ VAV+FA Sbjct 257 LLLGWGVFCNYGLMLMGLPAAAVLAAAPRPPRDGWTQWRAVLRALGPAALAAIAVAVAFA 316 Query 316 VAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAIS 375 VAGF WFDGYTLVQQRYWQGIAKDRPF YWSWANLACVVCAIGLG VAG+ RVFDRAAI Sbjct 317 VAGFYWFDGYTLVQQRYWQGIAKDRPFQYWSWANLACVVCAIGLGGVAGVGRVFDRAAIR 376 Query 376 RRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNA 435 RRSG LLLLAVLAA A ADLSMLSKAE ERIWLPFTIWLTAA ALLP R+HR+WLA+NA Sbjct 377 RRSGFPLLLLAVLAAAACADLSMLSKAEVERIWLPFTIWLTAAAALLPVRTHRIWLALNA 436 Query 436 AGALLLNSIIFTNW 449 GAL +N+II T+W Sbjct 437 VGALAVNTIILTHW 450 >gi|118463924|ref|YP_883732.1| integral membrane protein [Mycobacterium avium 104] gi|118165211|gb|ABK66108.1| integral membrane protein [Mycobacterium avium 104] Length=450 Score = 564 bits (1454), Expect = 1e-158, Method: Compositional matrix adjust. Identities = 339/434 (79%), Positives = 367/434 (85%), Gaps = 9/434 (2%) Query 25 PRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRL 84 PRLNLG++PR D+G ERFAT AGAAPIFG W H GWGT PAV A AVVAWGPV+A RL Sbjct 17 PRLNLGVRPRLDVGPERFATHAGAAPIFGEWLIHAGWGTGPAVALAAAVVAWGPVLAQRL 76 Query 85 PWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSR 144 WR LTL +WA AA WAF+LAMIDGWQRGFAGRLTTRDEYLW+VP + DI A +RTF+SR Sbjct 77 SWRALTLGSWAVAAGWAFALAMIDGWQRGFAGRLTTRDEYLWEVPRVTDIAAAVRTFSSR 136 Query 145 ILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVL 204 I+D+QP+SW THVSGHPPGALLTFVWLDR+GL GGGWAGL+CLL GSSAAAAVLI VR L Sbjct 137 IVDYQPHSWTTHVSGHPPGALLTFVWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVRAL 196 Query 205 ASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAG 264 A E ARR APFVA+APTAIW+AVSADGYFAGVAAWGIALLAVAVH RFPAL AAGAG Sbjct 197 ADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHRPLRFPALTAAGAG 256 Query 265 LLLGWGVFLNYGLVLIVLPGMAVLAA---------ADWRPVLRALGPAVLAALVVAVSFA 315 LLLGWGVF NYGL+L+ LP AVLAA WR VLRALGPA LAA+ VAV+FA Sbjct 257 LLLGWGVFCNYGLMLMGLPAAAVLAAAPRPPRDGWTQWRAVLRALGPAALAAIAVAVAFA 316 Query 316 VAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAIS 375 VAGF WFDGYTLVQQRYWQGIAKDRPF YWSWANLACVVCAIGLG VAG+ RVFDRAAI Sbjct 317 VAGFYWFDGYTLVQQRYWQGIAKDRPFQYWSWANLACVVCAIGLGGVAGVGRVFDRAAIR 376 Query 376 RRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNA 435 RRSG LLLLAVLAA A ADLSMLSKAE ERIWLPFTIWLTAA ALLP R+HR+WLA+NA Sbjct 377 RRSGFPLLLLAVLAAAACADLSMLSKAEVERIWLPFTIWLTAAAALLPVRTHRIWLALNA 436 Query 436 AGALLLNSIIFTNW 449 GAL +N+II T+W Sbjct 437 VGALAVNTIILTHW 450 >gi|126433320|ref|YP_001069011.1| hypothetical protein Mjls_0709 [Mycobacterium sp. JLS] gi|126233120|gb|ABN96520.1| putative conserved integral membrane protein [Mycobacterium sp. JLS] Length=451 Score = 541 bits (1394), Expect = 9e-152, Method: Compositional matrix adjust. Identities = 315/451 (70%), Positives = 358/451 (80%), Gaps = 2/451 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGI-KPRSDIGLERFATRAGAAPIFGYWDAHV 59 +R RRE +A A+G +LV AF++P L+LG+ P + ERF + AG AP+FG+W+AHV Sbjct 1 MRAHRRETIAAAVGLLLVVTAFIVPHLDLGVVTPLINATPERFRSFAGTAPVFGWWNAHV 60 Query 60 GWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLT 119 GWGT PAV VA V WG ++ RL WR L +TWAT+AAWAFSLAM+DGWQRGFAGRLT Sbjct 61 GWGTVPAVFLGVAAVVWGRTLSERLSWRTLVPATWATSAAWAFSLAMVDGWQRGFAGRLT 120 Query 120 TRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGG 179 R EYL QVP + DIP +RTF RILD+QP+SW+THVSGHPPGALLTFVWLDRIGL GG Sbjct 121 ARHEYLRQVPTVTDIPDAVRTFADRILDYQPDSWITHVSGHPPGALLTFVWLDRIGLGGG 180 Query 180 GWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAA 239 WAGL+CLL GSS AAA+L+AVR LA E+ AR APF+AVAPTAIW+AVSADGYFAGVAA Sbjct 181 AWAGLLCLLAGSSVAAAILVAVRALADERTARLAAPFLAVAPTAIWVAVSADGYFAGVAA 240 Query 240 WGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL-AAADWRPVLR 298 WGIALLA+AV R P L A GAGLLLGW VFLNYGLVL+ LP +AVL +ADWR LR Sbjct 241 WGIALLALAVRRVGRRPELFAVGAGLLLGWAVFLNYGLVLMALPALAVLICSADWRSALR 300 Query 299 ALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIG 358 AL PAV AA+V+ V F +AGF WFDGY LVQ+RYWQGIA DRPF YW WANLA VVCAIG Sbjct 301 ALLPAVGAAVVIVVVFVIAGFWWFDGYQLVQERYWQGIAVDRPFQYWGWANLASVVCAIG 360 Query 359 LGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAA 418 LGSVAGL RVFD AAI RSG HLL+L LAAI ADLSMLSKAETERIWLPFT+WL AA Sbjct 361 LGSVAGLGRVFDIAAIRARSGLHLLMLGALAAILCADLSMLSKAETERIWLPFTMWLVAA 420 Query 419 PALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ALLP R+ R WLA+N GALL+N +I TNW Sbjct 421 GALLPVRAQRWWLALNVLGALLINHLILTNW 451 >gi|108797694|ref|YP_637891.1| hypothetical protein Mmcs_0715 [Mycobacterium sp. MCS] gi|119866783|ref|YP_936735.1| hypothetical protein Mkms_0729 [Mycobacterium sp. KMS] gi|108768113|gb|ABG06835.1| putative conserved integral membrane protein [Mycobacterium sp. MCS] gi|119692872|gb|ABL89945.1| putative conserved integral membrane protein [Mycobacterium sp. KMS] Length=451 Score = 540 bits (1392), Expect = 1e-151, Method: Compositional matrix adjust. Identities = 314/451 (70%), Positives = 358/451 (80%), Gaps = 2/451 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGI-KPRSDIGLERFATRAGAAPIFGYWDAHV 59 +R RRE +A A+G +LV AF++P L+LG+ P + ERF + AG AP+FG+W+AHV Sbjct 1 MRAHRRETIAAAVGLLLVVTAFIVPHLDLGVVTPLINATPERFRSFAGTAPVFGWWNAHV 60 Query 60 GWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLT 119 GWGT PAV VA V WG ++ RL WR L +TWAT+AAWAFSLAM+DGWQRGFAGRLT Sbjct 61 GWGTVPAVFLGVAAVVWGRTLSERLSWRTLVPATWATSAAWAFSLAMVDGWQRGFAGRLT 120 Query 120 TRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGG 179 R EYL QVP + DIP +RTF RILD+QP+SW+THVSGHPPGALLTFVWLDRIGL GG Sbjct 121 ARHEYLRQVPTVTDIPDAVRTFADRILDYQPDSWITHVSGHPPGALLTFVWLDRIGLGGG 180 Query 180 GWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAA 239 WAGL+CLL GSS AAA+L+AVR LA E+ AR APF+AVAPTAIW+AVSADGYFAGVAA Sbjct 181 AWAGLLCLLAGSSVAAAILVAVRALADERAARLAAPFLAVAPTAIWVAVSADGYFAGVAA 240 Query 240 WGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL-AAADWRPVLR 298 WGIALLA+AV R P L A GAGLLLGW VFLNYGLVL+ LP +AVL +ADWR LR Sbjct 241 WGIALLALAVRRVGRRPELFAVGAGLLLGWAVFLNYGLVLMALPALAVLICSADWRSALR 300 Query 299 ALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIG 358 AL PA+ AA+V+ V F +AGF WFDGY LVQ+RYWQGIA DRPF YW WANLA VVCAIG Sbjct 301 ALLPAIGAAVVIVVVFVIAGFWWFDGYQLVQERYWQGIAVDRPFQYWGWANLASVVCAIG 360 Query 359 LGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAA 418 LGSVAGL RVFD AAI RSG HLL+L LAAI ADLSMLSKAETERIWLPFT+WL AA Sbjct 361 LGSVAGLGRVFDIAAIRARSGLHLLMLGALAAILCADLSMLSKAETERIWLPFTMWLVAA 420 Query 419 PALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ALLP R+ R WLA+N GALL+N +I TNW Sbjct 421 GALLPVRAQRWWLALNVLGALLINHLILTNW 451 >gi|15839937|ref|NP_334974.1| hypothetical protein MT0566 [Mycobacterium tuberculosis CDC1551] gi|13880076|gb|AAK44788.1| hypothetical protein MT0566 [Mycobacterium tuberculosis CDC1551] Length=493 Score = 528 bits (1359), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 272/274 (99%), Positives = 273/274 (99%), Gaps = 0/274 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW Sbjct 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLN 274 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFL Sbjct 241 GIALLAVAVHGATRFPALVAAGAGLLLGWGVFLQ 274 >gi|120401906|ref|YP_951735.1| putative integral membrane protein [Mycobacterium vanbaalenii PYR-1] gi|119954724|gb|ABM11729.1| putative conserved integral membrane protein [Mycobacterium vanbaalenii PYR-1] Length=451 Score = 503 bits (1295), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 307/449 (69%), Positives = 345/449 (77%), Gaps = 2/449 (0%) Query 3 IGRREGLAVAIGFVLVGAAFVLPRLNLGI-KPRSDIGLERFATRAGAAPIFGYWDAHVGW 61 IGR+E +AVA+G VLV AAFV+P L+LG+ P + ER + A APIFG+W+ HVG Sbjct 3 IGRKEAVAVAVGSVLVVAAFVIPHLDLGVVTPLINATPERLRSFADTAPIFGWWNTHVGA 62 Query 62 GTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTR 121 GT PA A V WGP +A RLPWR L +W + AWAFSLAM+DGWQRGFAGRLT R Sbjct 63 GTIPAFAIGAAAVLWGPPLAQRLPWRWLPWLSWTVSCAWAFSLAMVDGWQRGFAGRLTAR 122 Query 122 DEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW 181 EYL QVP + DIP LRTF RILD+QP+SW+THVSGHPPGALLTFVWLDRIGL GG W Sbjct 123 HEYLRQVPTVTDIPEALRTFAGRILDYQPDSWITHVSGHPPGALLTFVWLDRIGLGGGAW 182 Query 182 AGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWG 241 AGL+CLL GSS AAA+++ VR LA E AR APFVAVAPTAIWIAVSADGYFAGVAAWG Sbjct 183 AGLLCLLAGSSIAAAIVVTVRALADEDTARAAAPFVAVAPTAIWIAVSADGYFAGVAAWG 242 Query 242 IALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAV-LAAADWRPVLRAL 300 I LLA+AV G+ R P A G+GLLLGW VFLNYGLVL+ P +AV L AA W+ +R L Sbjct 243 ITLLALAVRGSVRQPVAAAIGSGLLLGWAVFLNYGLVLMAFPAVAVLLGAATWQAAVRTL 302 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 PAV+AAL V FA AGF WFDGY LVQ+RYWQGIA DRPF YW WAN A VVCAIGLG Sbjct 303 VPAVVAALAVVAVFAAAGFWWFDGYLLVQERYWQGIANDRPFQYWGWANFASVVCAIGLG 362 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 SVAGL RVFD AAI RRSG HLL+L L AI +ADLS LSKAETERIWLPFT+WL A+ A Sbjct 363 SVAGLGRVFDIAAIKRRSGLHLLVLGALLAIVVADLSRLSKAETERIWLPFTVWLVASTA 422 Query 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LLPPRS R WLA+N GAL +N +I TNW Sbjct 423 LLPPRSARWWLALNVIGALAINHLILTNW 451 >gi|118473533|ref|YP_885402.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155] gi|118174820|gb|ABK75716.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155] Length=454 Score = 494 bits (1271), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 310/454 (69%), Positives = 349/454 (77%), Gaps = 5/454 (1%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGI-KPRSDIGLERFATRAGAAPIFGYWDAHV 59 ++IGRRE +AV I +LV AAFV+P L+LGI P + + + A APIFG+W+AHV Sbjct 1 MQIGRRELVAVIIAILLVTAAFVVPHLDLGIVTPLINSTPAQIYSFADTAPIFGWWNAHV 60 Query 60 GWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLT 119 GWGT PAVL A V WGP VA RLPWR L L W T+A WAFSLAMIDGWQRGFAGRLT Sbjct 61 GWGTVPAVLIGAATVWWGPAVAQRLPWRALPLVAWVTSALWAFSLAMIDGWQRGFAGRLT 120 Query 120 TRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGG 179 R EYL QVP + DI LRTF+SRILDFQP+SW+THVSGHPPGALLTFVWLDRIGL GG Sbjct 121 ARHEYLRQVPSVTDIGEALRTFSSRILDFQPDSWITHVSGHPPGALLTFVWLDRIGLGGG 180 Query 180 GWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAA 239 WAGL+CLLVGSSAAAA+++A+R ++ E AR APFVAVAPTAIWIAVSADGYFAGVAA Sbjct 181 AWAGLLCLLVGSSAAAAIVVALRAVSGEATARLAAPFVAVAPTAIWIAVSADGYFAGVAA 240 Query 240 WGIALLAVAVHGAT---RFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAA-DWRP 295 WG+ALLA+AV + R A G+GLLLGWG+FLNYGL L L +AVL A DWR Sbjct 241 WGLALLALAVRDSVHRRRVALPTAVGSGLLLGWGIFLNYGLALAALIALAVLITAPDWRA 300 Query 296 VLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVC 355 LR PAV+A L V F VAGF WFDGYTLVQ+RYWQGIA +RPF YWSWANLA VVC Sbjct 301 ALRVAVPAVIAVLAVVAVFLVAGFWWFDGYTLVQERYWQGIANNRPFQYWSWANLASVVC 360 Query 356 AIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWL 415 AIGLGSVAG+ RVFD A R G +L++ L AI ADLSMLSKAETERIWLPFT+WL Sbjct 361 AIGLGSVAGIGRVFDIKAARRNPGLPMLVIGALLAITFADLSMLSKAETERIWLPFTVWL 420 Query 416 TAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 TAA ALLPPRSHR WL +N AGAL LN +I TNW Sbjct 421 TAAGALLPPRSHRWWLGLNVAGALALNHLILTNW 454 >gi|111021239|ref|YP_704211.1| hypothetical protein RHA1_ro04262 [Rhodococcus jostii RHA1] gi|110820769|gb|ABG96053.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=470 Score = 467 bits (1201), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 265/439 (61%), Positives = 313/439 (72%), Gaps = 4/439 (0%) Query 12 AIGFVLVGAAFVLPRL-NLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTA 70 A+ +LV AFV+PRL N I P E A AAP+FG+ D HVGWGT AV A Sbjct 35 ALALILVVVAFVVPRLGNETITPIVHRTAESVRDFADAAPLFGFRDVHVGWGTPVAVGVA 94 Query 71 VAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPG 130 VAVV+WGP +A RL WR LT+ W +A WA +LA++DGWQRGFA RLT+ DEYL +VP Sbjct 95 VAVVSWGPGLAQRLAWRRLTVGVWLASALWAMALALVDGWQRGFARRLTSTDEYLHEVPR 154 Query 131 IADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVG 190 + DIPATLR F RILD QP+SW THVSGHPPGALLTFVWLDRIGL GG WA +C+ VG Sbjct 155 VTDIPATLRGFAGRILDLQPDSWTTHVSGHPPGALLTFVWLDRIGLDGGAWASALCVAVG 214 Query 191 SSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVH 250 SSA AAV++AVR L E MARR APF+ +AP AIW+AVSAD FAGV AWGIALLA++ Sbjct 215 SSAGAAVIVAVRALGDEAMARRAAPFLVLAPAAIWVAVSADALFAGVVAWGIALLALSAT 274 Query 251 GATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVV 310 PALVA AG+LLG+GV+L+YGL L+ +P +AVL A R L A+ AL V Sbjct 275 RTVPVPALVAVTAGVLLGFGVYLSYGLTLMAIPAVAVLMIAR---TARPLVGALAGALAV 331 Query 311 AVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFD 370 A F + GF WFDGY LVQ+RY+QGIA DRPF YW WAN A +VCA+GL A L R F Sbjct 332 AAVFTLYGFWWFDGYQLVQERYYQGIASDRPFAYWGWANFASLVCAVGLAVPAALPRAFA 391 Query 371 RAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLW 430 + S +L+L+ LAA+ +ADLS LSKAETERIWLPF +WL AAPALLP SHR W Sbjct 392 WTRVRALSPVPVLVLSALAAVVIADLSALSKAETERIWLPFEVWLLAAPALLPRGSHRFW 451 Query 431 LAVNAAGALLLNSIIFTNW 449 LAV AAGAL +N ++FTNW Sbjct 452 LAVQAAGALAVNHLLFTNW 470 >gi|289744253|ref|ZP_06503631.1| integral membrane protein [Mycobacterium tuberculosis 02_1987] gi|289684781|gb|EFD52269.1| integral membrane protein [Mycobacterium tuberculosis 02_1987] Length=262 Score = 442 bits (1137), Expect = 5e-122, Method: Compositional matrix adjust. Identities = 233/233 (100%), Positives = 233/233 (100%), Gaps = 0/233 (0%) Query 217 VAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYG 276 VAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYG Sbjct 30 VAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYG 89 Query 277 LVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGI 336 LVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGI Sbjct 90 LVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGI 149 Query 337 AKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADL 396 AKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADL Sbjct 150 AKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADL 209 Query 397 SMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 SMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW Sbjct 210 SMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 262 >gi|289441926|ref|ZP_06431670.1| probable conserved integral membrane protein [Mycobacterium tuberculosis T46] gi|289414845|gb|EFD12085.1| probable conserved integral membrane protein [Mycobacterium tuberculosis T46] Length=280 Score = 435 bits (1119), Expect = 7e-120, Method: Compositional matrix adjust. Identities = 256/267 (96%), Positives = 258/267 (97%), Gaps = 5/267 (1%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW Sbjct 181 WAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAW 240 Query 241 GIALLAVAVHGA---TRFPALVAAGAG 264 GIALLA A GA FPALVAA +G Sbjct 241 GIALLAGA--GAWVPLAFPALVAARSG 265 >gi|226363585|ref|YP_002781367.1| hypothetical protein ROP_41750 [Rhodococcus opacus B4] gi|226242074|dbj|BAH52422.1| hypothetical membrane protein [Rhodococcus opacus B4] Length=470 Score = 428 bits (1101), Expect = 9e-118, Method: Compositional matrix adjust. Identities = 257/445 (58%), Positives = 306/445 (69%), Gaps = 4/445 (0%) Query 6 REGLAVAIGFVLVGAAFVLPRL-NLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTA 64 R+ + +LV AFV+P L N I P E A AAP+FG+ D HVGWGT Sbjct 29 RDFAGAGLALILVVVAFVVPYLGNETITPIVSRTAESVRDFADAAPLFGFRDVHVGWGTP 88 Query 65 PAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEY 124 A+ A AVV WGP +A L WR LT+ W +A WA +LA++DGWQRGF RLT+ DEY Sbjct 89 VAIAIAAAVVVWGPGLAQTLSWRPLTVGMWLGSALWAMALALVDGWQRGFVDRLTSTDEY 148 Query 125 LWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGL 184 L +V G+ DIPA LR F RILD QP+SW THVSGHPPGALLTFVWLDRIGL GG WA Sbjct 149 LHEVAGVTDIPAMLRGFADRILDLQPDSWTTHVSGHPPGALLTFVWLDRIGLDGGVWASA 208 Query 185 VCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIAL 244 +C+ VGSSA AAV++AVR L E ARR APF+ +AP IW+AVSAD FAGV AWGIAL Sbjct 209 LCVAVGSSAGAAVIVAVRALGDEATARRAAPFLVLAPAVIWVAVSADALFAGVVAWGIAL 268 Query 245 LAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAV 304 LA++ A PALVA AG+LLG+GV+L+YGL L+ +P +AVL A R L A+ Sbjct 269 LALSAARAVPVPALVAVAAGVLLGFGVYLSYGLTLMAIPAVAVLVIAR---TARPLAGAL 325 Query 305 LAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAG 364 AL VA F + GF WFDGY LVQ+RY+QGIA DRPF YW WAN A ++CA+GL A Sbjct 326 AGALAVAAVFTLCGFWWFDGYHLVQERYYQGIASDRPFAYWGWANFASLICAVGLAVPAA 385 Query 365 LSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPP 424 LSR + + S +L+LA L A+ +ADLS LSKAETERIWLPF WL AAPALLP Sbjct 386 LSRTLAWSRVRALSPVPVLVLAALLAVVIADLSALSKAETERIWLPFEWWLLAAPALLPR 445 Query 425 RSHRLWLAVNAAGALLLNSIIFTNW 449 SHR WLAV AAGAL +N ++FTNW Sbjct 446 GSHRFWLAVQAAGALAVNHLLFTNW 470 >gi|289744254|ref|ZP_06503632.1| integral membrane protein [Mycobacterium tuberculosis 02_1987] gi|289684782|gb|EFD52270.1| integral membrane protein [Mycobacterium tuberculosis 02_1987] Length=206 Score = 381 bits (978), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 194/196 (99%), Positives = 195/196 (99%), Gaps = 0/196 (0%) Query 1 VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 +RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG Sbjct 1 MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVG 60 Query 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT Sbjct 61 WGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTT 120 Query 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG Sbjct 121 RDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGG 180 Query 181 WAGLVCLLVGSSAAAA 196 WAGLVCLLVGSSAA A Sbjct 181 WAGLVCLLVGSSAATA 196 >gi|291453188|ref|ZP_06592578.1| integral membrane protein [Streptomyces albus J1074] gi|291356137|gb|EFE83039.1| integral membrane protein [Streptomyces albus J1074] Length=468 Score = 352 bits (903), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 220/414 (54%), Positives = 269/414 (65%), Gaps = 21/414 (5%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P+ W+ HVG GT A+ A AVVA+GP +A RLPWR L L+ WATA AW FSLA+I+G Sbjct 62 PLLASWNPHVGPGTPAALTVAAAVVAYGPALADRLPWRRLLLTAWATALAWIFSLALIEG 121 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLTT+ EYL + DIPA LR FT I+ P +W HV+GHPPGA LTFV Sbjct 122 WYRGIARRLTTKHEYLRVIDRFDDIPAALRGFTDHIVVGPPGNWPAHVAGHPPGATLTFV 181 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 WLDRIGL GG WAG+ C+++G+S AAVLIAVR LA E++ARR APF+A+AP A+W S Sbjct 182 WLDRIGLGGGAWAGVFCIVLGASGVAAVLIAVRALAGERLARRAAPFLALAPFAVWTGTS 241 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLP-GMAVL 288 ADGYFAGVAAW IALLAVA ATR L A +GLL GW +L+YGL LI LP +L Sbjct 242 ADGYFAGVAAWSIALLAVA---ATRRSLLAACASGLLFGWTCYLSYGLPLIALPLATVLL 298 Query 289 AAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWA 348 RPVL P + AAL V ++F + GF+W++ Y L+ +RY+QG RP+ YW W Sbjct 299 ITRTTRPVL----PFLAAALTVPLAFTLTGFAWWEAYPLLVERYYQGAGGVRPYAYWVWG 354 Query 349 NLACVVCAIGLGSVAGLSRVF-------------DRAAISRRSGCHLLLLAVLAAIALAD 395 NLA A+GL +VAGL R R A + + LL+LA L A+ AD Sbjct 355 NLAAATLAVGLATVAGLRRTLAATPSAALGALHPRRPAPTAEAALTLLVLAALLALLAAD 414 Query 396 LSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LS +SKAETERIW PF WL A ALLP R R WL A ALL+N +++T W Sbjct 415 LSGMSKAETERIWQPFYFWLLPATALLPVRGRRGWLGAQAGVALLVNHLVWTGW 468 >gi|254822009|ref|ZP_05227010.1| integral membrane protein [Mycobacterium intracellulare ATCC 13950] Length=245 Score = 331 bits (849), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 198/245 (81%), Positives = 212/245 (87%), Gaps = 1/245 (0%) Query 206 SEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGL 265 E ARR APFVA+APTAIW+AVSADGYFAGVAAWGIALLAVAVH RFPAL AA AGL Sbjct 1 DESTARRVAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHRPVRFPALTAAAAGL 60 Query 266 LLGWGVFLNYGLVLIVLPGMAVLAAA-DWRPVLRALGPAVLAALVVAVSFAVAGFSWFDG 324 LLGWGVF NYGL+L+ LP AVLA+A DWR +LRALGPA LAA+ VAV+FAVAGF WFDG Sbjct 61 LLGWGVFCNYGLMLMGLPAAAVLASAADWRAILRALGPAALAAIGVAVAFAVAGFYWFDG 120 Query 325 YTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLL 384 Y LVQQRYWQGIAKDRPF YWSWANLACVVCAIGLG VAGL RVFD AA+ RRSG HLLL Sbjct 121 YHLVQQRYWQGIAKDRPFQYWSWANLACVVCAIGLGGVAGLGRVFDGAAVRRRSGFHLLL 180 Query 385 LAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSI 444 L VLAA+ ADLSMLSKAE ERIWLPFTIWLTAA ALLP RSHR+WLA+NAAGA+ LN+I Sbjct 181 LGVLAAVVCADLSMLSKAEVERIWLPFTIWLTAATALLPVRSHRIWLALNAAGAIALNTI 240 Query 445 IFTNW 449 I TNW Sbjct 241 ILTNW 245 >gi|182440492|ref|YP_001828211.1| hypothetical protein SGR_6699 [Streptomyces griseus subsp. griseus NBRC 13350] gi|178469008|dbj|BAG23528.1| putative membrane protein [Streptomyces griseus subsp. griseus NBRC 13350] Length=479 Score = 328 bits (841), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 235/461 (51%), Positives = 292/461 (64%), Gaps = 26/461 (5%) Query 2 RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGW 61 R GR + +A A G +LV AA V+ R+ I+ R + RA P+ WD H+G Sbjct 32 RAGRADLVAAAGGGLLVTAAVVVGRV---IQNRDG------SLRAQWPPLLASWDPHLGP 82 Query 62 GTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTR 121 GT A++ AV VVA+GP +A RLPWR L + WA + AW S+A+IDGW RG A RLTT+ Sbjct 83 GTPAALVMAVLVVAYGPPLATRLPWRGLLAAAWAGSTAWVLSMALIDGWHRGVAKRLTTK 142 Query 122 DEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW 181 EYL + DIPATLR FT I+ +P +W H++GHPPGA LTFVWLDRIGL GG W Sbjct 143 HEYLRVIDRFEDIPATLRGFTDHIVIGEPGNWPAHIAGHPPGATLTFVWLDRIGLGGGAW 202 Query 182 AGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWG 241 A + C++VGSS A LI VRVLA E+ ARR APF+ +AP A+W VSADGYF VAAW Sbjct 203 AAVFCVVVGSSGVLAALITVRVLAGERPARRAAPFLVLAPAAVWAGVSADGYFTAVAAWS 262 Query 242 IALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADW-RPVLRAL 300 +ALLA+A RFPA AAG GLL GW +L+YGL L+ +AVL A RPV L Sbjct 263 VALLALAATRRVRFPAGAAAGGGLLFGWTCYLSYGLGLMAAVLLAVLVLARTARPVPLFL 322 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 L ALVV V+F + GF+W+ Y L+ +RY+QG RP+GYW WANLAC A GL Sbjct 323 ----LGALVVPVAFTLTGFNWWTAYHLLVERYYQGAGGVRPYGYWVWANLACATLAAGLA 378 Query 361 SVAGLSRVFDRA------------AISRRSGCHLLLLAVLAAIALADLSMLSKAETERIW 408 +VAG+ R A A S + LL+LA LAA+ ADLS +SKAETERIW Sbjct 379 AVAGVRRSAVAAPGALRALRGGSVAASPEAKVALLVLAALAALLAADLSGMSKAETERIW 438 Query 409 LPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 PF +WL A ALLP R R WLA +A ALL+N +++T W Sbjct 439 QPFLLWLLPATALLPRRGVRWWLAASAIPALLINHLLWTGW 479 >gi|326781162|ref|ZP_08240427.1| hypothetical protein SACT1_7053 [Streptomyces cf. griseus XylebKG-1] gi|326661495|gb|EGE46341.1| hypothetical protein SACT1_7053 [Streptomyces griseus XylebKG-1] Length=479 Score = 321 bits (823), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 225/465 (49%), Positives = 282/465 (61%), Gaps = 34/465 (7%) Query 2 RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGW 61 R GR + +A A G +LV AA V+ R+ I+ R + RA P+ WD H+G Sbjct 32 RAGRADLVAAAGGGLLVTAAVVVGRV---IQNRDG------SLRAQWPPLLASWDPHLGP 82 Query 62 GTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTR 121 GT A++ AV VVA+GP +A RLPWR L + WA + AW S+A+IDGW RG A RLTT+ Sbjct 83 GTPAALVMAVLVVAYGPPLATRLPWRGLLAAAWAGSTAWVLSMALIDGWHRGVAKRLTTK 142 Query 122 DEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW 181 EYL + DIPATLR FT I+ +P +W H++GHPPGA LTFVWLDRIGL GG W Sbjct 143 HEYLRVIDRFEDIPATLRGFTDHIVIGEPGNWPAHIAGHPPGATLTFVWLDRIGLGGGAW 202 Query 182 AGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWG 241 A + C++VGSS A A LI VRVLA E+ ARR APF+ +AP A+W VSADGYF VAAW Sbjct 203 AAVFCVVVGSSGALAALITVRVLAGERPARRAAPFLVLAPAAVWAGVSADGYFTAVAAWS 262 Query 242 IALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADW-RPVLRAL 300 +ALLA+A RFPA AAG GLL GW +L+YGL L+ +AVL A RPV L Sbjct 263 VALLALAATRRVRFPAGAAAGGGLLFGWTCYLSYGLGLMAAVLLAVLVLARTARPVPLFL 322 Query 301 GPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLG 360 L ALVV V+F +AGF+W+ Y L+ +RY+QG RP+GYW WANLAC A Sbjct 323 ----LGALVVPVAFTLAGFNWWTAYHLLVERYYQGAGGVRPYGYWVWANLACATLA---- 374 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALAD----------------LSMLSKAET 404 + R+A++ L +AA A LS +SKAET Sbjct 375 AGLAAVAGVRRSAVAAPGAVRALRGGSVAASPEAKVALLVLAALAALLAADLSGMSKAET 434 Query 405 ERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ERIW PF +WL A ALLP R R WLA +A ALL+N +++T W Sbjct 435 ERIWQPFLLWLLPATALLPRRGVRWWLAASALPALLINHLLWTGW 479 >gi|302530365|ref|ZP_07282707.1| hypothetical protein SSMG_06747 [Streptomyces sp. AA4] gi|302439260|gb|EFL11076.1| hypothetical protein SSMG_06747 [Streptomyces sp. AA4] Length=467 Score = 315 bits (806), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 218/414 (53%), Positives = 260/414 (63%), Gaps = 18/414 (4%) Query 48 AAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMI 107 A P+F +W HVG G+ AVL A VV +GP +A RL WR + + + AW FSLAM+ Sbjct 60 APPLFAHWLPHVGPGSVFAVLLAAGVVLYGPALAARLRWRRALAAGYLASLAWIFSLAMV 119 Query 108 DGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLT 167 DGW RGFAGRLTT EYL +VPGI DIP LR F+SRILDFQPNSW THVSGHPPGA L Sbjct 120 DGWTRGFAGRLTTPQEYLHEVPGITDIPRFLREFSSRILDFQPNSWTTHVSGHPPGATLV 179 Query 168 FVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIA 227 FVWLDR+GLRGG WA +LV + A AV + +L AR T PF ++P A+W+ Sbjct 180 FVWLDRLGLRGGAWASTAVVLVAALVAVAVPATIALLGRPGAARATLPFAVLSPGAVWLG 239 Query 228 VSADGYFAGVAAWGIALLAVA-----VHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVL 282 VSADG FAGV A GIALLA+A G +P +A AG+L+G+G+FL+YGLVL+ L Sbjct 240 VSADGLFAGVTATGIALLALASVGFRARGGYAWPTALA--AGVLVGFGIFLSYGLVLLGL 297 Query 283 PGMAVLAAA-DWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRP 341 +AV WR AVL AL V FA+AGF WFDGY LV +RY+QG+A RP Sbjct 298 VALAVALLGRQWRAAAV----AVLGALAVVAVFALAGFWWFDGYHLVVERYYQGVALVRP 353 Query 342 FGYWSWANLACVVCAIGLGSVAGLSRVFDRAAI--SRRS----GCHLLLLAVLAAIALAD 395 + YW WA+LA V A G VA R A SRR+ L++LA L I AD Sbjct 354 YSYWVWADLAAVAVACGPAVVAAARRGVATAVFLPSRRTILRDPVLLIVLAALLTIVFAD 413 Query 396 LSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 S LSKAE ERIWLPF WL A ALLP R WLA A AL +N ++ TNW Sbjct 414 SSGLSKAEVERIWLPFGAWLLPATALLPAGHRRWWLAGQAVVALAVNHLLLTNW 467 >gi|291300407|ref|YP_003511685.1| hypothetical protein Snas_2917 [Stackebrandtia nassauensis DSM 44728] gi|290569627|gb|ADD42592.1| hypothetical protein Snas_2917 [Stackebrandtia nassauensis DSM 44728] Length=462 Score = 312 bits (800), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 225/465 (49%), Positives = 285/465 (62%), Gaps = 39/465 (8%) Query 9 LAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVL 68 +AVA G LVGAAF + L ++P +D G+ + A PI H G GT A+ Sbjct 13 IAVACGAALVGAAF---WVGLSVEPVADSGV--YWPPLSAKPI-----PHFGAGTPLAIA 62 Query 69 TAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQV 128 AVAV+ +GPV+A RL WR L + W A AW F+LA++DGW+RG AG+LT+ +EYL + Sbjct 63 VAVAVIGYGPVLAARLRWRALVVVAWLAAIAWTFALALVDGWRRGIAGQLTSDNEYLSII 122 Query 129 PGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLL 188 DI A LR ++ IL P +W HV+GHPPGA+LTFV LDR+GL GG WAG+ C++ Sbjct 123 GRFDDIGAALRGYSDHILIDAPANWPAHVAGHPPGAVLTFVGLDRLGLGGGAWAGVWCIV 182 Query 189 VGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVA 248 VG SA AA+L+AVR LA E +ARR+APF+ ++P AIWI VSADGYFA VAAWGIALL +A Sbjct 183 VGCSAVAAILVAVRALAGEDLARRSAPFLVLSPAAIWIGVSADGYFAAVAAWGIALLVLA 242 Query 249 VHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAAL 308 R+P LVA GAGLL G V+L+YGL LI + + VL R L ++ A Sbjct 243 ARRECRWPWLVALGAGLLFGAAVYLSYGLTLIAVVAVGVLLITR---TARPLPLVLIGAC 299 Query 309 VVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSR- 367 VV ++F +AGF W++ Y L+ +RY QG R + YW W NLA V IG VAGL R Sbjct 300 VVPLAFTLAGFYWWEAYFLLAERYDQGAGGVRSYAYWVWGNLAAAVIVIGPAVVAGLRRS 359 Query 368 -VFDRAAISRRSGCHLLLLAVLAAI----------------------ALADLSMLSKAET 404 V AAI RR +A AAI A+ADLS +SKAET Sbjct 360 AVAAPAAI-RRFPMRPSAVAAPAAIRPSPKTGQDRFVLLLLAALVAIAVADLSGMSKAET 418 Query 405 ERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ERIWLPFT+WL A ALLP R RLWL A AL++N + T+W Sbjct 419 ERIWLPFTVWLIPAAALLPDR-RRLWLGAQALLALVVNHALLTSW 462 >gi|329937269|ref|ZP_08286868.1| integral membrane protein [Streptomyces griseoaurantiacus M045] gi|329303550|gb|EGG47436.1| integral membrane protein [Streptomyces griseoaurantiacus M045] Length=452 Score = 311 bits (797), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 223/420 (54%), Positives = 265/420 (64%), Gaps = 24/420 (5%) Query 47 GAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAM 106 G P++ W+ HVG GT A+L AV VV +GP +A RLPWR L + W TA AW FSLA+ Sbjct 40 GWPPLYATWEPHVGPGTPAALLVAVLVVVYGPPLAARLPWRALLGAVWGTALAWTFSLAL 99 Query 107 IDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALL 166 +DGWQRG A RLTTR EYL V +DIPATLR FT IL P W HV+GHPP + L Sbjct 100 VDGWQRGLARRLTTRYEYLNAVDRFSDIPATLRDFTHHILIDSPAHWPPHVAGHPPASTL 159 Query 167 TFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWI 226 TFV LDRIGL GG WAG+ C+LVG+SAA AVL+ VR LASE+MARR APF VAP A+W+ Sbjct 160 TFVLLDRIGLGGGAWAGVWCVLVGTSAAVAVLVTVRALASEEMARRAAPFTVVAPAAVWV 219 Query 227 AVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMA 286 SADGYFAGVAAW +A LA+AV G R P GAGLL G V+L+YGL L + A Sbjct 220 GASADGYFAGVAAWAVACLALAVTG--RRPWAFGLGAGLLFGLTVYLSYGLTLFAVLAGA 277 Query 287 VLAAADWRPVLRALGPAVLAAL-VVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYW 345 VL RP A+ P +LA VV V F GF W++ Y L+ +RY+QG RP+GYW Sbjct 278 VLLLGTRRP---AVLPWLLAGCAVVPVVFTCLGFDWWEAYRLLVRRYYQGAGGIRPYGYW 334 Query 346 SWANLACVVCAIGLGSVAGLSRVFD-RAAISRRSGCH---------------LLLLAVLA 389 WANLAC V G +V GL R RR+G +L A L Sbjct 335 VWANLACTVLVAGPATVVGLRRTGGVLVGAVRRTGVRARPRPARWSSEVRLSVLAWAALG 394 Query 390 AIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 A+ ADLS +SKAETERIWLPF +WL AA AL+ R R+WLA A ALLLN ++ T W Sbjct 395 ALLAADLSGMSKAETERIWLPFVMWLLAAGALV--REVRVWLAAQAVLALLLNHLLLTGW 452 >gi|320012495|gb|ADW07345.1| hypothetical protein Sfla_5959 [Streptomyces flavogriseus ATCC 33331] Length=467 Score = 306 bits (783), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 214/410 (53%), Positives = 266/410 (65%), Gaps = 13/410 (3%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P+ WD HVG GT A+ AVAVVA+GP +A RLPWR L L+ WA + AW SLA+++G Sbjct 61 PLLASWDPHVGPGTPLALGVAVAVVAYGPRLAARLPWRRLLLTCWAGSVAWILSLALVEG 120 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLTT+ EYL + DI A LR FT I+ P +W HV+GHPPGA LTFV Sbjct 121 WYRGVARRLTTKHEYLRVIDRFDDIGAALRGFTDHIVIGPPGNWPAHVAGHPPGATLTFV 180 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDRIGL GG WAG C+++G SAAAAVL+A+R L E +ARR APF+ +AP A+W S Sbjct 181 GLDRIGLGGGAWAGTWCIVLGGSAAAAVLVALRALTGEHLARRAAPFLVLAPFAVWTGTS 240 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLA 289 ADGYF VAAW +ALLA+A RFPA+ A +GLL G+ +L+YGL LI + AVL Sbjct 241 ADGYFTAVAAWSVALLALAATRTVRFPAVAALASGLLFGFTCYLSYGLTLIAVLPAAVLV 300 Query 290 AADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWAN 349 + LGP +L ALV V+F +AGF+W++ Y L+ +RY+QG RPF YW W N Sbjct 301 MTR---TVGPLGPFLLGALVAPVAFTLAGFNWWEAYHLLVERYYQGAGGVRPFSYWVWGN 357 Query 350 LACVVCAIGLGSVAGLSRVFDRAAISRR---SGC-------HLLLLAVLAAIALADLSML 399 LAC A GL +VAGL R A + R SG +L LA L A+A+ADLS + Sbjct 358 LACATLAAGLATVAGLRRAAASAPAALRGLLSGTATGVQRLAVLTLAALLAVAVADLSGM 417 Query 400 SKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 SKAETERIW PF +WL A ALLP R WLA AA ALL+N +++T W Sbjct 418 SKAETERIWQPFVLWLMPAAALLPDGDRRAWLAAQAAVALLVNHLLWTGW 467 >gi|300790131|ref|YP_003770422.1| hypothetical protein AMED_8323 [Amycolatopsis mediterranei U32] gi|299799645|gb|ADJ50020.1| conserved hypothetical protein [Amycolatopsis mediterranei U32] gi|340531811|gb|AEK47016.1| hypothetical protein RAM_42745 [Amycolatopsis mediterranei S699] Length=465 Score = 294 bits (753), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 215/410 (53%), Positives = 259/410 (64%), Gaps = 14/410 (3%) Query 48 AAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMI 107 A P+F W HVG G+ AVL AVAVV GP +A RLPWR + + + AW FSLAM+ Sbjct 62 APPLFADWLPHVGPGSVFAVLVAVAVVLHGPALAARLPWRRTLAAGYLASLAWIFSLAMV 121 Query 108 DGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLT 167 DGW RGFAG LT EYL +VPGI DIP LR F+SRILDF+P SW THVSGHPPGA L Sbjct 122 DGWGRGFAGHLTIPQEYLHEVPGITDIPRMLREFSSRILDFRPQSWTTHVSGHPPGATLV 181 Query 168 FVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIA 227 FVWLDR+GL GG WA +LVGS A AV + +L + AR PF + P A+WI Sbjct 182 FVWLDRLGLHGGAWAATAVVLVGSLVAVAVPATLALLGRPEAAREVLPFAVLTPGAVWIG 241 Query 228 VSADGYFAGVAAWGIALLAVAVHGAT---RFPALVAAGAGLLLGWGVFLNYGLVLIVLPG 284 VSADG FAGV A G+ALL ++ G T R+ GAG+LLG+G+FL+YGLVL+ + Sbjct 242 VSADGLFAGVTATGLALLVLSATGFTHGRRYAVPAGLGAGVLLGFGIFLSYGLVLLGVLV 301 Query 285 MAVLAAA-DWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFG 343 +AV WR A++AAL V FA AGF W DGY LV +RY+QG+A RP+ Sbjct 302 LAVAVLGRQWRAAAL----AIVAALAVVGVFAWAGFWWLDGYHLVVERYYQGVALVRPYS 357 Query 344 YWSWANLACVVCAIGLGSVAGLSRVFDRAAISRR----SGCHLLLLAVLAAIALADLSML 399 YW WA+LA V A+G VA + R A+ RR LL LA LAAI AD+S L Sbjct 358 YWVWADLAAVTVALGPAVVAAVRRGL--ASSPRRALLTDPVLLLGLAALAAILFADVSGL 415 Query 400 SKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 SKAETERIWLPF +WL ALLP + WLA AA AL +N ++ T W Sbjct 416 SKAETERIWLPFGVWLLPMTALLPRPGRQWWLAAQAATALAVNHLLLTGW 465 >gi|345009966|ref|YP_004812320.1| hypothetical protein Strvi_2316 [Streptomyces violaceusniger Tu 4113] gi|344036315|gb|AEM82040.1| hypothetical protein Strvi_2316 [Streptomyces violaceusniger Tu 4113] Length=465 Score = 291 bits (744), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 210/411 (52%), Positives = 262/411 (64%), Gaps = 13/411 (3%) Query 49 APIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMID 108 AP++ W HVG GT A+ A AVV GP +A RLPWR L + WA + AW +SLA++D Sbjct 58 APLYADWLPHVGPGTPAALAVAAAVVVHGPRLAVRLPWRGLLGAVWAASMAWIWSLALVD 117 Query 109 GWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTF 168 GWQRG AGRLT R EYL V DI A LR FT IL QP+ W H++GHPPGA+LTF Sbjct 118 GWQRGVAGRLTARHEYLRGVDRFHDIGAALRGFTGHILLTQPDHWPAHIAGHPPGAVLTF 177 Query 169 VWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAV 228 V LDR+GL GGGWAG C+ VG SAA A+L+ +R L E+ AR APF+ +AP A+W+ Sbjct 178 VGLDRLGLGGGGWAGAFCITVGGSAAVAILVTLRALGQERAARAAAPFLVLAPGAVWVGA 237 Query 229 SADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL 288 SADGYFA VAAWG+ALLA+A R P VA G+GLLLG +L+YGL L+ LP AVL Sbjct 238 SADGYFAAVAAWGLALLALAATRTVRAPGAVAFGSGLLLGLTAYLSYGLTLLALPAAAVL 297 Query 289 AAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWA 348 A R L A++ A VVA +F +AGF W++GY+L+ +RY+QG+A DRP+ YW WA Sbjct 298 LLAR---TARPLPFALIGAAVVAGAFTLAGFQWWEGYSLLVERYYQGVASDRPYAYWVWA 354 Query 349 NLACVVCAIGLGSVAGLSRVFDRAAISRR----------SGCHLLLLAVLAAIALADLSM 398 NLA G VAG R+ + R G +L AVL A+ +ADLS Sbjct 355 NLAVATVVAGPACVAGARRMLSAVPDTVRRLRPGGPGAPDGLVVLTFAVLFALVVADLSG 414 Query 399 LSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 +SKAETERIWLPF +WL ALLP R WLA A L++N ++ T W Sbjct 415 MSKAETERIWLPFLVWLLPTAALLPAVDRRRWLAAQACLGLIVNHLLLTGW 465 >gi|297155367|gb|ADI05079.1| hypothetical protein SBI_01958 [Streptomyces bingchenggensis BCW-1] Length=454 Score = 285 bits (730), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 205/403 (51%), Positives = 247/403 (62%), Gaps = 27/403 (6%) Query 47 GAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAM 106 G P+F W+ H+G GT AV AVAVV +GP +A RLPWR L + W TA AWA+SLA+ Sbjct 27 GWPPLFASWNPHLGPGTPAAVAVAVAVVGYGPPLAARLPWRALLAAAWGTAMAWAWSLAL 86 Query 107 IDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALL 166 +DGW RG A RLTTR+EYL + DIPA L FT IL P W H++GHPP A L Sbjct 87 VDGWHRGVATRLTTRNEYLQVIDRFHDIPAALGDFTHHILLDSPGHWPAHIAGHPPAATL 146 Query 167 TFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWI 226 TFV LDR+GL GGGWAG C+ VG++A AVLI VR L E +ARR APF+ AP A+W+ Sbjct 147 TFVLLDRVGLGGGGWAGAWCITVGATACVAVLITVRALTDEDLARRAAPFLVAAPAAVWM 206 Query 227 AVSADGYFAGVAAWGIALLAVAV-HGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGM 285 A SADGYFA VAAW +ALLA++V A VA GAGLL G +L+YGL LI L Sbjct 207 ATSADGYFAAVAAWSVALLALSVTERAGARRRAVAFGAGLLSGLTCYLSYGLTLIALIAG 266 Query 286 AVLAAADWR-PVLRALGPAVLAAL-VVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFG 343 AVL R L L P LA VV + F +AGFSW++ Y L+ +RY+QG RP+G Sbjct 267 AVLVLGRVRGRDLAQLSPFPLAGFAVVPLLFTLAGFSWWEAYRLLVERYYQGAGGIRPYG 326 Query 344 YWSWANLACVVCAIGLGSVAGLSRVFDRAAISRR----SGCH------------------ 381 YW WANLAC V GL ++AGL R A+ R G H Sbjct 327 YWVWANLACTVLITGLATMAGLRRACATLALVRHGAVMPGRHGAVIRRPDPPSRPVAEPR 386 Query 382 --LLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALL 422 LL+ A L A+ +ADLS +SKAETERIWLPF +WL A A L Sbjct 387 LALLVSAALLALLIADLSGMSKAETERIWLPFAMWLLTACAFL 429 >gi|302554744|ref|ZP_07307086.1| integral membrane protein [Streptomyces viridochromogenes DSM 40736] gi|302472362|gb|EFL35455.1| integral membrane protein [Streptomyces viridochromogenes DSM 40736] Length=443 Score = 284 bits (726), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 212/409 (52%), Positives = 255/409 (63%), Gaps = 16/409 (3%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P+ W H+G GT AVL A+A V GP +A RLPWR L W T AAW SLA++DG Sbjct 42 PLLASWGPHLGPGTPAAVLVAIATVVHGPALAARLPWRALLPVAWGTGAAWICSLALVDG 101 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 WQRG A RLTTR EYL + DIPA LR FT IL P++W HV+GHPP A LTFV Sbjct 102 WQRGIARRLTTRYEYLQVIDRFHDIPAALRDFTRHILLDSPDNWPAHVAGHPPAATLTFV 161 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDR GLRGGGWAG+ C+ VG++A AVL+AVR LA E++ARR APF+ +AP A+W+ S Sbjct 162 LLDRAGLRGGGWAGIWCIAVGATACVAVLVAVRALAGERLARRAAPFLVLAPAAVWMGTS 221 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLA 289 AD YFA VAAW +ALLA+AV G + + A +GLL G +L+YGL L+ L AVLA Sbjct 222 ADAYFAAVAAWAVALLALAVTGRSFW---WAGASGLLFGLTCYLSYGLTLVALIAAAVLA 278 Query 290 AAD----WRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYW 345 RP L L P + VV +F +AGF W++ Y L+ RY QG RP+GYW Sbjct 279 LGQGGIRERPAL--LVPLLAGLAVVPTAFTLAGFDWWEAYRLLVTRYHQGAGGIRPYGYW 336 Query 346 SWANLACVVCAIGLGSVAGLSR---VFDRAAISRRSGCHL--LLLAVLAAIALADLSMLS 400 WANLAC V GL + AGL R V R G L L+ L A+ LADLS +S Sbjct 337 VWANLACAVIVTGLATAAGLRRTGAVLRGRHTEPRDGVRLAVLVCGALLALLLADLSGMS 396 Query 401 KAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 KAETERIWLPF +WL A ALLP R WL A ALLLN ++ T W Sbjct 397 KAETERIWLPFAVWLLPACALLP--RPRAWLTAQAVLALLLNHLLRTGW 443 >gi|345003433|ref|YP_004806287.1| hypothetical protein SACTE_5963 [Streptomyces sp. SirexAA-E] gi|344319059|gb|AEN13747.1| conserved hypothetical protein [Streptomyces sp. SirexAA-E] Length=473 Score = 273 bits (697), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 227/458 (50%), Positives = 285/458 (63%), Gaps = 21/458 (4%) Query 2 RIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGW 61 R+ RR L A G VL+ A VL + ++ R + + P+ WD H G Sbjct 27 RVARRRDLIAAGGGVLLIVAAVL--VGRAVQDRDG------SLQVQWPPLLASWDPHTGP 78 Query 62 GTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTR 121 GT AV AVAV+A+GP +A RLPWR L L+ W + AW SLA+I+GW RG A RLTT+ Sbjct 79 GTPAAVAVAVAVIAYGPGLAARLPWRRLLLTCWTASLAWILSLALIEGWYRGVARRLTTK 138 Query 122 DEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW 181 EYL V D+ A LR FT I+ P +W HV+GHPPGA LTFV LDR GL GG W Sbjct 139 HEYLRAVDRFDDVGAALRGFTDHIVIGPPGNWPAHVAGHPPGATLTFVGLDRAGLGGGAW 198 Query 182 AGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWG 241 AG C+++G SAA A LIA+R LA ++ARR APF+ +AP A+W SAD YFA VAAW Sbjct 199 AGAWCIVLGGSAAVAALIALRALAGVEIARRAAPFLVLAPFAVWAGTSADAYFAAVAAWS 258 Query 242 IALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALG 301 +ALLA+A TRFP+ A GAGLL G +L+YGL LI P +AVL A R G Sbjct 259 VALLALAATRTTRFPSAAALGAGLLFGLTCYLSYGLTLIAAPLLAVLVLAR---TARPAG 315 Query 302 PAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGS 361 P +L ALVV +F +AGF+W++GY L+ +RY+QG RPF YW W NLAC A GL + Sbjct 316 PFLLGALVVPAAFTLAGFNWWEGYHLLVERYYQGAGGTRPFSYWVWGNLACATLAAGLAT 375 Query 362 VAGLSRV---FDRAAISRRSG-------CHLLLLAVLAAIALADLSMLSKAETERIWLPF 411 VAG+ RV A + R+G LL+LA L A+ +ADLS +SKAETERIW PF Sbjct 376 VAGMRRVAVTVPSAVRALRAGTPSPAQRTALLVLAALLALLVADLSGMSKAETERIWQPF 435 Query 412 TIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 +WL A ALLP R+ R WLA A ALL+N +++T W Sbjct 436 LLWLLPAAALLPARNRRGWLAAQALVALLVNHLLWTGW 473 >gi|159038329|ref|YP_001537582.1| integral membrane protein [Salinispora arenicola CNS-205] gi|157917164|gb|ABV98591.1| integral membrane protein [Salinispora arenicola CNS-205] Length=468 Score = 265 bits (677), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 201/426 (48%), Positives = 250/426 (59%), Gaps = 32/426 (7%) Query 45 RAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSL 104 A AAP+F W H+GWGT AVL A VV WG A PW L + W TA AW SL Sbjct 50 HADAAPLFATWRPHLGWGTPAAVLVAAVVVGWGLPWARTAPWGRLLAAGWLTAVAWTLSL 109 Query 105 AMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGA 164 A++DGW G A RLT + EYL +VP I D+PA L FT RILDFQP SW TH +GHPPGA Sbjct 110 ALVDGWSAGLAERLTPQAEYLHEVPRITDVPAMLAGFTGRILDFQPESWSTHTAGHPPGA 169 Query 165 LLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAI 224 LL FVWLDRIGL GG AGL C+LVG++ ++ +A+R L + AR PF+ + P A+ Sbjct 170 LLVFVWLDRIGLGGGAAAGLACVLVGATVTVSIPMALRALGAGDAARTVVPFLVLLPGAV 229 Query 225 WIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPG 284 W+ SADG FAGV A G+ALL V L+A GL+LG+ + L+YG VL+ L Sbjct 230 WVGASADGLFAGVVAAGLALLVVGGR-------LLATVGGLVLGFALHLSYGFVLVGLLA 282 Query 285 MAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGY 344 +AVL R L A VV ++F AGF W+DGY LV +RY+QG A DRP+ Y Sbjct 283 LAVLTLRA-RHRWTTLVAAGAGVAVVVLAFTAAGFWWWDGYGLVVERYYQGWAADRPYAY 341 Query 345 WSWANLACVVCAIGLGSVAGLSRVFDRAAISR---------------------RSGCHLL 383 W WANLA ++ + G L R AA SR RS + Sbjct 342 WVWANLAALLLSAGPAVGPALRRTALEAA-SRVRAAAWPRPPRPTGATVADAVRSAGPTV 400 Query 384 LLAVLAAIAL--ADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLL 441 +L + AA+ + ADLS LSKAE ERIWLPF +WL A A LP +HR WLA A AL + Sbjct 401 VLPLTAALVVVAADLSGLSKAEVERIWLPFAVWLLVAVAHLPAHTHRWWLAGQALTALAV 460 Query 442 NSIIFT 447 N +++T Sbjct 461 NHLLWT 466 >gi|290955003|ref|YP_003486185.1| protein [Streptomyces scabiei 87.22] gi|260644529|emb|CBG67614.1| putative integral membrane protein [Streptomyces scabiei 87.22] Length=440 Score = 262 bits (670), Expect = 8e-68, Method: Compositional matrix adjust. Identities = 209/411 (51%), Positives = 257/411 (63%), Gaps = 17/411 (4%) Query 47 GAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAM 106 G P++ W H G GT A+ AVAVVA+GP +A RLPWR L S WA A AW FSLA+ Sbjct 39 GWPPLYAVWLPHTGPGTPAAIAVAVAVVAYGPPLAARLPWRPLLWSVWAAALAWTFSLAL 98 Query 107 IDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALL 166 +DGW RG A RLTTR EYL + DIPATLR+FT IL + W HV+GHPPGA L Sbjct 99 VDGWHRGIARRLTTRYEYLQVIDRFDDIPATLRSFTDHILLGTADHWPPHVAGHPPGATL 158 Query 167 TFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWI 226 TFV LDRIGL GGGWAG + VG++ AVL+ VR LASE +ARR APF+ +AP A+W+ Sbjct 159 TFVLLDRIGLAGGGWAGAFVITVGATGTVAVLLTVRTLASEALARRAAPFLVLAPAAVWM 218 Query 227 AVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMA 286 SADGYFA VAAW +A LA+AV G P A +GLL G ++L+YGL L + A Sbjct 219 GTSADGYFAAVAAWAVAFLALAVTGHR--PRPTAFLSGLLFGLVLYLSYGLTLFAVIAAA 276 Query 287 VLAAADWRPVLRALGPAVLAAL-VVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYW 345 VL R A+ P LA L VV ++F +AGF W++ Y L+ +RY QG RP+ Y+ Sbjct 277 VLLLGSRR---AAVLPFALAGLAVVPLAFTLAGFDWWEAYRLLVERYHQGAGGFRPYVYF 333 Query 346 SWANLACVVCAIGLGSVAGLSRV-------FDRAAISRRSGCHLLLLAVLAAIALADLSM 398 WANLAC V +G +VAGL R RR+G LL A L + +ADLS Sbjct 334 VWANLACTVLVVGPATVAGLRRTGALLGRWHASPVPERRTGL--LLAAALLMLLVADLSG 391 Query 399 LSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 +SKAETERIWLPF +WL A+ A L R+WL AA LLLN ++ T W Sbjct 392 MSKAETERIWLPFALWLLASGAFL--DRPRVWLVSQAALGLLLNHLLLTGW 440 >gi|134099881|ref|YP_001105542.1| integral membrane protein [Saccharopolyspora erythraea NRRL 2338] gi|291006082|ref|ZP_06564055.1| integral membrane protein [Saccharopolyspora erythraea NRRL 2338] gi|133912504|emb|CAM02617.1| integral membrane protein [Saccharopolyspora erythraea NRRL 2338] Length=434 Score = 262 bits (669), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 202/406 (50%), Positives = 251/406 (62%), Gaps = 12/406 (2%) Query 46 AGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLA 105 A +APIFG+ H G GT PAV+TAVAVVA+GP +A RL W +L + +A + W F LA Sbjct 39 ADSAPIFGFVSPHFGPGTLPAVVTAVAVVAFGPSLAERLSWPLLLAAGYAASLCWTFFLA 98 Query 106 MIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGAL 165 +++GW G A RLT EYL VP + DIPA L FT IL FQP SW HVSGHPPGAL Sbjct 99 LVEGWHDGIALRLTHEPEYLHDVPRVTDIPAMLSGFTDHILAFQPGSWTVHVSGHPPGAL 158 Query 166 LTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIW 225 LT+VWLDRIGL GG WA + LLVGS AA AV +AVR LA AR PF+ + P A+W Sbjct 159 LTYVWLDRIGLGGGAWAAALSLLVGSLAAVAVAVAVRALAGADAARAALPFLVLFPGAVW 218 Query 226 IAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLI--VLP 283 + VSADG F GV A G+AL + G A G+LL WG+FLNYGLVL+ + Sbjct 219 VGVSADGVFMGVVATGVALFTLGATGRGLRADAAAVAGGVLLSWGIFLNYGLVLMAPFVV 278 Query 284 GMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFG 343 G+A+L RP+L LG A A+ V ++FA AGF W DGY LV +RY QG RP+ Sbjct 279 GVALLTRRV-RPLL--LGAA--GAVTVVLAFAAAGFWWLDGYHLVVERYHQGEFALRPYS 333 Query 344 YWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAE 403 YW W N+ ++ + G ++ V R A R+ + + A A+ AD+S LSKAE Sbjct 334 YWVWGNVGALLLSAG-----PVAAVIARRAAVTRTAVAVPVAAAAVAVLAADISGLSKAE 388 Query 404 TERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 ERIWLPF +W A ALLP R WLAV A AL +N ++ TNW Sbjct 389 VERIWLPFAVWFCAGAALLPRAHRRGWLAVQAVTALAVNHLVVTNW 434 >gi|21222159|ref|NP_627938.1| integral membrane protein [Streptomyces coelicolor A3(2)] gi|7211014|emb|CAB76994.1| putative integral membrane protein [Streptomyces coelicolor A3(2)] Length=456 Score = 261 bits (666), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 210/424 (50%), Positives = 258/424 (61%), Gaps = 28/424 (6%) Query 47 GAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAM 106 G P+ G WD H+G GT AVL A V A+GP VA RLPWR L + W TA AW +SLA+ Sbjct 40 GWPPLLGRWDPHLGPGTPAAVLVAAGVAAYGPAVAARLPWRALLPAAWGTALAWTWSLAL 99 Query 107 IDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALL 166 IDGW+RG AGRLTT EYL V D+PATLR F IL P++W HV+GHPPGA L Sbjct 100 IDGWERGVAGRLTTSQEYLSVVDRWHDVPATLRDFNGHILLHSPDNWPAHVAGHPPGATL 159 Query 167 TFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWI 226 T+V LDRIGL GGGWAG + + VG++A AVL+AVR L E++ARR APF+A+AP A+W+ Sbjct 160 TYVLLDRIGLGGGGWAGALTITVGATACVAVLVAVRALTGERLARRAAPFLALAPAAVWM 219 Query 227 AVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMA 286 SADGYFA VAA +A+ TR AAG+GLL G +L+YGL L + A Sbjct 220 GTSADGYFAAVAA---WAVALLALAVTRRSPGWAAGSGLLFGLTCYLSYGLTLFAVIAAA 276 Query 287 VLAAADWRPVLRA----LGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPF 342 VL R +RA L + A VV V+F AGF W++ Y L+ RY++G A RP+ Sbjct 277 VLVLG--RRGVRARPVLLAALLAGAAVVPVAFTAAGFDWWEAYRLLVTRYYEGAAGVRPY 334 Query 343 GYWSWANLACVVCAIGLGSVAGLSR----VFDRAAISRRSGCH-------------LLLL 385 YW WANLAC V GL +VAGL R + R A R+G L+ Sbjct 335 AYWVWANLACTVLITGLATVAGLRRAGGVLLRRRAGDVRTGGERADGERAGEVRLAFLVA 394 Query 386 AVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSII 445 A L A+ ADLS +SKAETERIWLPF +WL AA A L R WL A ALL+N ++ Sbjct 395 AGLLALLAADLSGMSKAETERIWLPFALWLLAACAFLT--RPRGWLTAQAVLALLVNHLV 452 Query 446 FTNW 449 T W Sbjct 453 ATGW 456 >gi|295838765|ref|ZP_06825698.1| integral membrane protein [Streptomyces sp. SPB74] gi|295827176|gb|EFG65288.1| integral membrane protein [Streptomyces sp. SPB74] Length=377 Score = 259 bits (661), Expect = 8e-67, Method: Compositional matrix adjust. Identities = 177/323 (55%), Positives = 221/323 (69%), Gaps = 9/323 (2%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P++ +W+ HVG GT A+L A AVV +GP +A RLPWR L L+ WA AW FSLA IDG Sbjct 41 PLYAHWEPHVGPGTPAALLVAAAVVLYGPPLAARLPWRPLLLTAWAAGTAWTFSLAWIDG 100 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLT+R EYL + DIPATLR FT IL P W H +GHPP A +TFV Sbjct 101 WYRGIAERLTSRYEYLRVIDRFQDIPATLRDFTHHILLDSPGHWPPHTAGHPPAATVTFV 160 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDR+GL GGGWAG+ C++VG+SA AAVL+A+R LASE++ARR APF+ +AP A+W+ VS Sbjct 161 LLDRVGLGGGGWAGMWCVVVGASAGAAVLVALRALASEELARRAAPFLVLAPAAVWVGVS 220 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL- 288 ADGYFA VAAW +ALLA+AV G R PA AAG+GLL G ++L+YGL L + G AVL Sbjct 221 ADGYFAAVAAWAVALLALAVTG--RSPAW-AAGSGLLFGLALYLSYGLTLFAVIGGAVLL 277 Query 289 ---AAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYW 345 A RPVL A L +VV F GF+W++ Y ++ +RY+QG RP+GY+ Sbjct 278 LGRAEVRRRPVLLAYPLGGL--VVVPAVFTALGFNWWEAYHILVERYYQGAGGKRPYGYF 335 Query 346 SWANLACVVCAIGLGSVAGLSRV 368 WANLAC V +GL +VAGL R Sbjct 336 VWANLACTVFVVGLATVAGLRRC 358 >gi|302868411|ref|YP_003837048.1| integral membrane protein [Micromonospora aurantiaca ATCC 27029] gi|302571270|gb|ADL47472.1| integral membrane protein [Micromonospora aurantiaca ATCC 27029] Length=467 Score = 249 bits (635), Expect = 8e-64, Method: Compositional matrix adjust. Identities = 193/460 (42%), Positives = 245/460 (54%), Gaps = 61/460 (13%) Query 34 RSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLST 93 R+ +GL A AAP++ W H+GWGT A+ AVAVV G A W L Sbjct 21 RAGVGLH-----ADAAPLYATWRPHLGWGTPAALAIAVAVVGPGTQWARTARWGPLLSVG 75 Query 94 WATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSW 153 + A W +LA++DGW G RLT + EYL +VP + D+ L F RILDFQP+SW Sbjct 76 YLAAVGWTLALALVDGWSAGLTTRLTAQAEYLHEVPRVTDVGRMLAGFADRILDFQPDSW 135 Query 154 VTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRT 213 TH +GHPPGALL FV LDR+GL GG A + C+LVG+S +V I +R L + AR + Sbjct 136 STHTAGHPPGALLVFVALDRVGLGGGTAAAMACVLVGASVVVSVPIVLRALGAGGAARTS 195 Query 214 APFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFL 273 PF+ + P A+W SADG F GV A G+ALLAV R A AG G+LLG+ ++L Sbjct 196 LPFLVLLPGAVWAGASADGLFTGVVAAGLALLAV------RGTATALAG-GVLLGFALYL 248 Query 274 NYGLVLIVLPGMAVLAAADWRPVLR--ALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQR 331 +YG VL+ + VLA RP R AL VA F VAGF W+ GY V +R Sbjct 249 SYGFVLVAPLALVVLAL---RPGGRVAALLAGATGVATVATVFTVAGFHWWQGYDRVVER 305 Query 332 YWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRA------------------- 372 Y+QG A DRP+ YW WANLA ++ + G L R A Sbjct 306 YYQGWAADRPYAYWVWANLAALLLSAGPVVGPALRRTLHAARAWRGWDGSPAPAAWTPGT 365 Query 373 ---------------------AISRRSG----CHLLLLAVLAAIALADLSMLSKAETERI 407 A++RR G LL A + A+ ADLS +SKAE ERI Sbjct 366 GRPAPGGDPLTHVAVRNRRLGALARRVGTLGPTVLLPAAAVLAVLAADLSGMSKAEVERI 425 Query 408 WLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFT 447 WLPFT+WL A A LP +HR WLA A AL +N ++FT Sbjct 426 WLPFTVWLLVAVAHLPAATHRWWLAGQALTALAVNHLVFT 465 >gi|29831112|ref|NP_825746.1| hypothetical protein SAV_4569 [Streptomyces avermitilis MA-4680] gi|29608226|dbj|BAC72281.1| putative membrane protein [Streptomyces avermitilis MA-4680] Length=473 Score = 246 bits (627), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 208/417 (50%), Positives = 253/417 (61%), Gaps = 41/417 (9%) Query 47 GAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAM 106 G P++ + HVG GT A+ AVAVVA+GP +A RLPWR L + WATA AW FSLA+ Sbjct 39 GWPPLYAVAEPHVGAGTPAALAVAVAVVAYGPALAARLPWRALLAAAWATATAWTFSLAL 98 Query 107 IDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALL 166 +DGWQRG AGRLTT+ EYL + DIP TLR FT IL P W HV+GHPP A L Sbjct 99 VDGWQRGIAGRLTTQYEYLRVIDRFHDIPGTLRDFTHHILIDSPGHWPAHVAGHPPAAPL 158 Query 167 TFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWI 226 TFV LDRIGL GGGWAG+ C+ VG++A AVL+ VRVLA E +ARR APF+ +AP A+W+ Sbjct 159 TFVLLDRIGLGGGGWAGVWCITVGATACVAVLVTVRVLAGEVLARRAAPFLVLAPAAVWM 218 Query 227 AVSADGYFAGVAAWGIALLAVAVHGATRFPALV----------------------AAGAG 264 SADGYFA VAAW +ALLA+AV G T A G+G Sbjct 219 GTSADGYFAAVAAWAVALLALAVTGGTGRTGGAGRTGGAGQTGGAGRTGHRVWAAAFGSG 278 Query 265 LLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAAL-VVAVSFAVAGFSWFD 323 LL G +L+YGL L + VL R +R L P + A L VV + F +AGF W++ Sbjct 279 LLFGLTCYLSYGLTLFAVIAAGVLVLG--RERVRVL-PLLFAGLAVVPLVFTLAGFHWWE 335 Query 324 GYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSR-----VFDRAAISRRS 378 Y L+ +RY+QG RP+GYW WAN AC V +GL +VAGL R V R + R Sbjct 336 AYRLLVERYYQGAGGLRPYGYWVWANPACTVLVVGLATVAGLRRAGVALVRQRGQVLRSR 395 Query 379 GC---------HLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLP-PR 425 LL+ A L A+ ADLS +SKAETERIWLPF +WL AA A LP PR Sbjct 396 DAPGPAAEPRLALLVYAALLALLAADLSGMSKAETERIWLPFAMWLLAAGAFLPRPR 452 >gi|254822075|ref|ZP_05227076.1| integral membrane protein [Mycobacterium intracellulare ATCC 13950] Length=177 Score = 243 bits (621), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 129/176 (74%), Positives = 146/176 (83%), Gaps = 0/176 (0%) Query 6 REGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAP 65 R+ +AV+IG LV AAFVLPR+NLG++PR D+G E+FAT AG+APIFG W H GWGT P Sbjct 2 RDAVAVSIGAALVAAAFVLPRMNLGVRPRLDVGAEKFATHAGSAPIFGEWLIHAGWGTGP 61 Query 66 AVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYL 125 A+ AV VVAWGP +A RL WR LTL +WA A WAF+LAMIDGWQRGFAGRLTTRDEYL Sbjct 62 AIALAVVVVAWGPTLAQRLSWRALTLGSWAVAGGWAFALAMIDGWQRGFAGRLTTRDEYL 121 Query 126 WQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW 181 QVPG+ DIPATLRTF RI+D+QP+SW THVSGHPPGALLTFVWLDRIGL GG W Sbjct 122 SQVPGVTDIPATLRTFAGRIVDYQPHSWTTHVSGHPPGALLTFVWLDRIGLHGGAW 177 >gi|326328829|ref|ZP_08195165.1| putative membrane protein [Nocardioidaceae bacterium Broad-1] gi|325953451|gb|EGD45455.1| putative membrane protein [Nocardioidaceae bacterium Broad-1] Length=451 Score = 239 bits (610), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 173/438 (40%), Positives = 240/438 (55%), Gaps = 17/438 (3%) Query 20 AAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPV 79 A V P L + PR I F P+ G+ VG GT PAVL A+A V W Sbjct 23 AVLVPPLLGWQVWPRVHIEDGTFP------PLHGFPQVKVGIGTVPAVLLALASVRWADP 76 Query 80 VAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLR 139 VA RLPWR L + +A W SLA++DG G +G L +R EYL + D+ LR Sbjct 77 VATRLPWRRLLVVAYAAGLVWLLSLALVDG-VEGISGVLGSRSEYLGTARAVDDVGGLLR 135 Query 140 TFTSRI-LDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVL 198 + +RI D +W H++GHPPG +L FV L ++GL G AGLV ++ ++ A AV+ Sbjct 136 EYVARIPYDAPDGNWPVHIAGHPPGMVLFFVLLVKVGLGGDLAAGLVVTVIAATLAPAVM 195 Query 199 IAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPAL 258 VRVL SE AR AP++ + P+A+++AVSAD A AAWG+ LA+A G R Sbjct 196 TTVRVLGSEAGARAAAPYLVLTPSAVFLAVSADAVMAATAAWGMCCLALACRGGLRRGWP 255 Query 259 VAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAAD-----WRPVLRALGPAVLAALVVAVS 313 A AGLLLG+ V ++YG L+ + +AVL W L A ++AL V + Sbjct 256 WAVAAGLLLGYLVMMSYGHPLVGVLALAVLWLGSGRRWGWARGWWVLPVAAVSALGVVLV 315 Query 314 FAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIG--LGSVAGLSRVFDR 371 FA GF+W++ Y ++ RYW G+A RP YW+W NLA + + G +G+ G + R Sbjct 316 FAAGGFAWWEAYPVLVDRYWDGLASQRPGAYWTWGNLAALAISAGPLVGAGIGAAWASRR 375 Query 372 AAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWL 431 R + ++ +ALAD+S +S+AE ERIWLPF WLT ALLP R R L Sbjct 376 NLEDRVVVVLVAAALIM--VALADVSQMSRAEVERIWLPFIPWLTLGCALLPERWRRPGL 433 Query 432 AVNAAGALLLNSIIFTNW 449 A+ ALL+ ++ T+W Sbjct 434 ALQLGTALLVEHLLHTSW 451 >gi|88856675|ref|ZP_01131331.1| putative integral membrane protein [marine actinobacterium PHSC20C1] gi|88814136|gb|EAR24002.1| putative integral membrane protein [marine actinobacterium PHSC20C1] Length=430 Score = 236 bits (602), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 180/449 (41%), Positives = 255/449 (57%), Gaps = 29/449 (6%) Query 11 VAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTA 70 +A VL+ A V+P L G +A P+ W HVG GT PA++ A Sbjct 1 MAAAIVLITVAIVIPALT---------GWNVYANHF--PPLHALWMPHVGPGTIPAIVLA 49 Query 71 VAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPG 130 + ++ WG A RLPW+ L +++A + W SLA++DG G L + EYL Sbjct 50 IVLIRWGSAAASRLPWKQLLAASFAASLLWLASLALVDG-PSGLGAILNSGHEYLPVART 108 Query 131 IADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGW--AGLVCLL 188 + D+ L+ F SRI ++W THV+GHPPGALL F L + GL G W AG++ ++ Sbjct 109 VTDVGVLLQEFISRIPLESTDNWPTHVAGHPPGALLFFWVLAQWGL--GNWLAAGIIVIV 166 Query 189 VGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVA 248 +G+S AVL+ +R L +E AR APF+ P AIW+AVSADG F AAWG+ LLA+A Sbjct 167 LGASVPVAVLVTLRQLDAESHARAAAPFLVAGPAAIWMAVSADGMFTAFAAWGLCLLAMA 226 Query 249 VHG-ATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL-AAADWRPVLRALGPAVLA 306 ++R A AG++LG+ VFL+YGL+LI + +A+L A +W P L A+ + Sbjct 227 ASAKSSRAVAGWGVAAGIILGFCVFLSYGLILIGVLAIAILVVAKNWTP----LPWALAS 282 Query 307 ALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIG------LG 360 A +VAV+FA+AGF+W++ Y ++ +RYW GIA RP YW WAN+A + + G + Sbjct 283 AAIVAVAFAIAGFAWWEAYPVIVERYWDGIASRRPLEYWIWANIAALAISAGPVLGAAIA 342 Query 361 SVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPA 420 S A R F R +++ L A L ++ LADLS +SK E ERIWLPF W+ A A Sbjct 343 STASRLRHF-RNNVAQDRVVVWLAAAALTSVLLADLSGMSKGEVERIWLPFVPWILIATA 401 Query 421 LLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 +PP R A ALL+ ++FT W Sbjct 402 WIPPHLRRGVYASQLIFALLVQHLLFTGW 430 >gi|333026935|ref|ZP_08454999.1| putative integral membrane protein [Streptomyces sp. Tu6071] gi|332746787|gb|EGJ77228.1| putative integral membrane protein [Streptomyces sp. Tu6071] Length=516 Score = 220 bits (561), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 169/320 (53%), Positives = 210/320 (66%), Gaps = 5/320 (1%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P++ W+ HVG GT A+L A AVV GP + RLPWR L L+ WA A AW FSLA IDG Sbjct 41 PLYARWEPHVGPGTPAAILVAAAVVLHGPPLVARLPWRALLLAVWAAATAWTFSLAWIDG 100 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLT+R EYL + DIPATLR FT IL P+ W H +GHPP A +TFV Sbjct 101 WYRGIAERLTSRYEYLRVIDRFQDIPATLRDFTHHILLDSPHHWPPHTAGHPPAATVTFV 160 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDR+GL GGGWAG+ C++VG+SA A LIAVR LA E +ARR A F+ +AP A+W+ VS Sbjct 161 LLDRVGLGGGGWAGMWCIVVGASAGVAALIAVRALAGEDLARRAALFLVLAPAAVWVGVS 220 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAV-- 287 ADGYFA VAAW +ALLA+AV G R PA AAG+GLL G ++L+YGL L + G AV Sbjct 221 ADGYFAAVAAWAVALLALAVTG--RSPAW-AAGSGLLFGLALYLSYGLTLFAVIGCAVLL 277 Query 288 LAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSW 347 L R L + +VV F GF+W++ Y ++ +RY+QG RP+GY+ W Sbjct 278 LGRHGVRRKPVLLLYLLAGLVVVPAVFTALGFNWWEAYHILVERYYQGAGGKRPYGYFVW 337 Query 348 ANLACVVCAIGLGSVAGLSR 367 ANLA V +GL +VAGL R Sbjct 338 ANLAGTVLVVGLATVAGLRR 357 Score = 45.1 bits (105), Expect = 0.027, Method: Compositional matrix adjust. Identities = 23/30 (77%), Positives = 25/30 (84%), Gaps = 1/30 (3%) Query 397 SMLSKAETERIWLPFTIWLTAAPALLP-PR 425 S +SKAETERIWLPFT+WL A ALLP PR Sbjct 466 SGMSKAETERIWLPFTVWLLPAAALLPRPR 495 >gi|318061573|ref|ZP_07980294.1| integral membrane protein [Streptomyces sp. SA3_actG] Length=506 Score = 220 bits (560), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 169/320 (53%), Positives = 210/320 (66%), Gaps = 5/320 (1%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P++ W+ HVG GT A+L A AVV GP + RLPWR L L+ WA A AW FSLA IDG Sbjct 41 PLYARWEPHVGPGTPAAILVAAAVVLHGPPLVARLPWRALLLAVWAAATAWTFSLAWIDG 100 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLT+R EYL + DIPATLR FT IL P+ W H +GHPP A +TFV Sbjct 101 WYRGIAERLTSRYEYLRVIDRFQDIPATLRDFTHHILLDSPHHWPPHTAGHPPAATVTFV 160 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDR+GL GGGWAG+ C++VG+SA A LIAVR LA E +ARR A F+ +AP A+W+ VS Sbjct 161 LLDRVGLGGGGWAGMWCIVVGASAGVAALIAVRALAGEDLARRAALFLVLAPAAVWVGVS 220 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLA 289 ADGYFA VAAW +ALLA+AV G R PA AAG+GLL G ++L+YGL L + G AVL Sbjct 221 ADGYFAAVAAWAVALLALAVTG--RSPAW-AAGSGLLFGLALYLSYGLTLFAVIGCAVLL 277 Query 290 AADW--RPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSW 347 R L + +VV F GF+W++ Y ++ +RY+QG RP+GY+ W Sbjct 278 LGRHGVRRKPVLLLYLLAGLVVVPAVFTALGFNWWEAYHILVERYYQGAGGKRPYGYFVW 337 Query 348 ANLACVVCAIGLGSVAGLSR 367 ANLA V +GL +VAGL R Sbjct 338 ANLAGTVLVVGLATVAGLRR 357 Score = 50.4 bits (119), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 33/53 (63%), Positives = 38/53 (72%), Gaps = 2/53 (3%) Query 397 SMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 S +SKAETERIWLPFT+WL A ALLP RLWL A ALLLN ++ T+W Sbjct 456 SGMSKAETERIWLPFTVWLLPAAALLP--GPRLWLTAQAVLALLLNHLLLTSW 506 >gi|302519218|ref|ZP_07271560.1| integral membrane protein [Streptomyces sp. SPB78] gi|302428113|gb|EFK99928.1| integral membrane protein [Streptomyces sp. SPB78] Length=479 Score = 219 bits (558), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 170/320 (54%), Positives = 210/320 (66%), Gaps = 5/320 (1%) Query 50 PIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDG 109 P++ W+ HVG GT A+L A AVV GP + RLPWR L L+ WA A AW FSLA IDG Sbjct 14 PLYARWEPHVGPGTPAAILVAAAVVLHGPPLVARLPWRALLLAVWAAATAWTFSLAWIDG 73 Query 110 WQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFV 169 W RG A RLT+R EYL + DIPATLR FT IL P+ W H +GHPP A +TFV Sbjct 74 WYRGIAERLTSRYEYLRVIDRFQDIPATLRDFTHHILLDSPHHWPPHTAGHPPAATVTFV 133 Query 170 WLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVS 229 LDR+GL GGGWAG+ C++VG+SA A LIAVR LA E +ARR A F+ +AP A+W+ VS Sbjct 134 LLDRVGLGGGGWAGMWCIVVGASAGVAALIAVRALAGEDLARRAALFLVLAPAAVWVGVS 193 Query 230 ADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAV-- 287 ADGYFA VAAW +ALLA+AV G R PA AAG+GLL G ++L+YGL L + G AV Sbjct 194 ADGYFAAVAAWAVALLALAVTG--RSPAW-AAGSGLLFGLALYLSYGLTLFAVIGCAVLL 250 Query 288 LAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSW 347 L R L + LVV F GF+W++ Y ++ +RY+QG RP+GY+ W Sbjct 251 LGRHGVRRKPVLLLYLLAGLLVVPAVFTALGFNWWEAYHILVERYYQGAGGKRPYGYFVW 310 Query 348 ANLACVVCAIGLGSVAGLSR 367 ANLA V +GL +VAGL R Sbjct 311 ANLAGTVLVVGLATVAGLRR 330 Score = 50.8 bits (120), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 33/53 (63%), Positives = 38/53 (72%), Gaps = 2/53 (3%) Query 397 SMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 S +SKAETERIWLPFT+WL A ALLP RLWL A ALLLN ++ T+W Sbjct 429 SGMSKAETERIWLPFTVWLLPAAALLP--GPRLWLTAQAVLALLLNHLLLTSW 479 >gi|302541882|ref|ZP_07294224.1| integral membrane protein [Streptomyces hygroscopicus ATCC 53653] gi|302459500|gb|EFL22593.1| integral membrane protein [Streptomyces himastatinicus ATCC 53653] Length=469 Score = 217 bits (552), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 219/414 (53%), Positives = 269/414 (65%), Gaps = 16/414 (3%) Query 49 APIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMID 108 AP++ W H G GT AV AVAVVA GP +A LPWR L + WATA AW ++LA++D Sbjct 59 APLYADWLPHAGPGTPAAVALAVAVVAHGPRIAATLPWRRLLWAGWATAMAWTWALALVD 118 Query 109 GWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTF 168 GW RG AGRLT R EYL + DI A LR FT IL QP+ W H++GHPPGA+LTF Sbjct 119 GWGRGVAGRLTQRHEYLRGIDRFHDIGAALRGFTGHILITQPDHWPAHIAGHPPGAVLTF 178 Query 169 VWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAV 228 V LDR+GL GGGWAG C+ GSSA AAVL+ +R L E+ AR APF+ +AP A+W+ Sbjct 179 VGLDRLGLGGGGWAGAFCITAGSSAVAAVLVTLRALGQERAARTAAPFLVLAPAAVWVGA 238 Query 229 SADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL 288 SADGYFA VAAWG+ALLA+A TR P VA AGLLLG +++YGL L+ LP AVL Sbjct 239 SADGYFAAVAAWGLALLALAATRTTRAPGAVALAAGLLLGLTAYVSYGLTLMALPAAAVL 298 Query 289 AAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWA 348 A +R L A+ A VA +F +AGF+W++GY L+ +RY+QG+A DRP+GYW WA Sbjct 299 LLAR---TVRPLPYALAGAAAVAGAFTLAGFAWWEGYDLLVERYYQGVAADRPYGYWVWA 355 Query 349 NLACVVCAIGLGSVA----------GLSRVFDRAAISRRSGCH---LLLLAVLAAIALAD 395 NLA A GL SVA G R R + G +L+LA L A+A A+ Sbjct 356 NLANAAIAAGLASVAGARRAVGAAPGAVRRLRRGDLGGEGGADGLVVLVLAALLALATAN 415 Query 396 LSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW 449 LS +SKAETERIWLPF +WL A ALLP R R WLA AA ALL+N ++ T W Sbjct 416 LSGMSKAETERIWLPFVLWLLPAAALLPARDLRRWLAAQAALALLVNHLLLTGW 469 Lambda K H 0.327 0.139 0.460 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 930863295684 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40