BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0567
Length=339
Score E
Sequences producing significant alignments: (Bits) Value
gi|15839965|ref|NP_335002.1| tetracenpmycin polyketide synthesis... 689 0.0
gi|15607707|ref|NP_215081.1| methyltransferase/methylase [Mycoba... 687 0.0
gi|31791749|ref|NP_854242.1| methyltransferase/methylase [Mycoba... 685 0.0
gi|340625594|ref|YP_004744046.1| putative methyltransferase/meth... 677 0.0
gi|183980955|ref|YP_001849246.1| methyltransferase/methylase [My... 561 5e-158
gi|118616484|ref|YP_904816.1| methyltransferase/methylase [Mycob... 556 2e-156
gi|254432782|ref|ZP_05046485.1| tetracenomycin polyketide synthe... 421 9e-116
gi|220905879|ref|YP_002481190.1| O-methyltransferase family 2 [C... 390 2e-106
gi|115373042|ref|ZP_01460345.1| tetracenomycin polyketide synthe... 389 4e-106
gi|197104541|ref|YP_002129918.1| methyltransferase/methylase [Ph... 377 1e-102
gi|254431102|ref|ZP_05044805.1| tetracenomycin polyketide synthe... 324 1e-86
gi|302039074|ref|YP_003799396.1| o-methyltransferase [Candidatus... 315 7e-84
gi|296445285|ref|ZP_06887244.1| O-methyltransferase family 2 [Me... 305 9e-81
gi|220925549|ref|YP_002500851.1| O-methyltransferase family 2 [M... 305 1e-80
gi|223937003|ref|ZP_03628911.1| O-methyltransferase family 2 [ba... 304 1e-80
gi|332708639|ref|ZP_08428612.1| O-methyltransferase [Lyngbya maj... 304 1e-80
gi|73539379|ref|YP_299746.1| O-methyltransferase family protein ... 300 2e-79
gi|295676181|ref|YP_003604705.1| O-methyltransferase family 2 [B... 296 2e-78
gi|323138579|ref|ZP_08073647.1| O-methyltransferase family 2 [Me... 296 2e-78
gi|311745287|ref|ZP_07719072.1| tetracenomycin polyketide synthe... 296 3e-78
gi|87302194|ref|ZP_01085019.1| O-methyltransferase, family 2 [Sy... 293 3e-77
gi|116626250|ref|YP_828406.1| O-methyltransferase family protein... 292 7e-77
gi|171913856|ref|ZP_02929326.1| O-methyltransferase, family 2 [V... 291 9e-77
gi|209518561|ref|ZP_03267381.1| O-methyltransferase family 2 [Bu... 290 3e-76
gi|82703424|ref|YP_412990.1| putative transcriptional regulator ... 286 3e-75
gi|307726176|ref|YP_003909389.1| O-methyltransferase family 2 [B... 286 5e-75
gi|323529544|ref|YP_004231696.1| O-methyltransferase family 2 [B... 283 2e-74
gi|186473411|ref|YP_001860753.1| O-methyltransferase family prot... 278 8e-73
gi|302548369|ref|ZP_07300711.1| tetracenomycin polyketide synthe... 277 2e-72
gi|162449489|ref|YP_001611856.1| methyltransferase [Sorangium ce... 250 2e-64
gi|330467585|ref|YP_004405328.1| O-methyltransferase family 2 [V... 218 8e-55
gi|283484099|gb|ADB23385.1| O-methyltransferase [Micromonospora ... 217 3e-54
gi|161367427|gb|ABX71152.1| Lcz35 [Streptomyces sanglieri] 215 1e-53
gi|134099420|ref|YP_001105081.1| putative 8-O-methyltransferase ... 213 5e-53
gi|197116283|dbj|BAG68852.1| O-methyltransferase, family 2 [Stre... 210 2e-52
gi|254389419|ref|ZP_05004646.1| O-methyltransferase [Streptomyce... 207 2e-51
gi|326444140|ref|ZP_08218874.1| O-methyltransferase family 2 [St... 207 3e-51
gi|117956311|gb|ABK58689.1| PdmT [Actinomadura hibisca] 204 1e-50
gi|196232088|ref|ZP_03130943.1| O-methyltransferase family 2 [Ch... 203 4e-50
gi|302540363|ref|ZP_07292705.1| tetracenomycin polyketide synthe... 201 2e-49
gi|73621289|gb|AAZ78343.1| OxyT [Streptomyces rimosus] 197 2e-48
gi|730914|sp|P39896.1|TCMO_STRGA RecName: Full=Tetracenomycin po... 197 2e-48
gi|161367392|gb|ABX71118.1| Lct35 [Streptomyces rishiriensis] 193 4e-47
gi|154623247|emb|CAM34375.1| putative O-methyltransferase [Strep... 186 4e-45
gi|292659126|gb|ADE34508.1| SsfM1 [Streptomyces sp. SF2575] 182 7e-44
gi|40644841|emb|CAE17534.1| O-methyltransferase [Streptomyces gr... 180 4e-43
gi|229014702|ref|ZP_04171812.1| O-methyltransferase, family 2 [B... 175 9e-42
gi|302843296|ref|XP_002953190.1| hypothetical protein VOLCADRAFT... 173 3e-41
gi|154623239|emb|CAM34367.1| putative O-methyltransferase [Strep... 173 4e-41
gi|291442186|ref|ZP_06581576.1| O-methyltransferase family 2 [St... 172 6e-41
>gi|15839965|ref|NP_335002.1| tetracenpmycin polyketide synthesis 8-o-methyltransferase [Mycobacterium
tuberculosis CDC1551]
gi|253797499|ref|YP_003030500.1| methyltransferase/methylase [Mycobacterium tuberculosis KZN 1435]
gi|254230909|ref|ZP_04924236.1| hypothetical protein TBCG_00562 [Mycobacterium tuberculosis C]
28 more sequence titles
Length=340
Score = 689 bits (1777), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 339/339 (100%), Positives = 339/339 (100%), Gaps = 0/339 (0%)
Query 1 VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
Sbjct 2 VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 61
Query 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
Sbjct 62 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 121
Query 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC
Sbjct 122 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 181
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
Sbjct 182 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 241
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
Sbjct 242 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 301
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
Sbjct 302 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 340
>gi|15607707|ref|NP_215081.1| methyltransferase/methylase [Mycobacterium tuberculosis H37Rv]
gi|148660336|ref|YP_001281859.1| tetracenpmycin polyketide synthesis 8-o-methyltransferase [Mycobacterium
tuberculosis H37Ra]
gi|148821768|ref|YP_001286522.1| methyltransferase [Mycobacterium tuberculosis F11]
36 more sequence titles
Length=339
Score = 687 bits (1773), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 338/339 (99%), Positives = 339/339 (100%), Gaps = 0/339 (0%)
Query 1 VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
+ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
Sbjct 1 MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
Query 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
Sbjct 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
Query 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC
Sbjct 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
Sbjct 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
Sbjct 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
Sbjct 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
>gi|31791749|ref|NP_854242.1| methyltransferase/methylase [Mycobacterium bovis AF2122/97]
gi|121636485|ref|YP_976708.1| putative methyltransferase/methylase [Mycobacterium bovis BCG
str. Pasteur 1173P2]
gi|224988957|ref|YP_002643644.1| putative methyltransferase/methylase [Mycobacterium bovis BCG
str. Tokyo 172]
8 more sequence titles
Length=339
Score = 685 bits (1767), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 337/339 (99%), Positives = 338/339 (99%), Gaps = 0/339 (0%)
Query 1 VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
+ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
Sbjct 1 MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
Query 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
Sbjct 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
Query 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC
Sbjct 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
ADGLLSRIVAAAHPHLQCVS DLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV
Sbjct 181 ADGLLSRIVAAAHPHLQCVSLDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
Sbjct 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
Sbjct 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
>gi|340625594|ref|YP_004744046.1| putative methyltransferase/methylase [Mycobacterium canettii
CIPT 140010059]
gi|340003784|emb|CCC42910.1| putative methyltransferase/methylase [Mycobacterium canettii
CIPT 140010059]
Length=339
Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/339 (99%), Positives = 337/339 (99%), Gaps = 0/339 (0%)
Query 1 VELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
+ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA
Sbjct 1 MELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDA 60
Query 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT
Sbjct 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
Query 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLA+RFPFERYRRLCDVG
Sbjct 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAERFPFERYRRLCDVGG 180
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQA AGDFLADPLPAADV
Sbjct 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQAFAGDFLADPLPAADV 240
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF
Sbjct 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK
Sbjct 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
>gi|183980955|ref|YP_001849246.1| methyltransferase/methylase [Mycobacterium marinum M]
gi|183174281|gb|ACC39391.1| methyltransferase/methylase [Mycobacterium marinum M]
Length=340
Score = 561 bits (1446), Expect = 5e-158, Method: Compositional matrix adjust.
Identities = 270/336 (81%), Positives = 299/336 (89%), Gaps = 0/336 (0%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
SPDRIMAIG GYGPSKVLLTAVGLGLFTELGD AMTA+AIA+ LGL+ RPA DFLDALVS
Sbjct 5 SPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQAIAELLGLVPRPATDFLDALVS 64
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
LDLLARDGDGP + YRNT ETA +LDEA P Y GGLLKIW++RNYRFWADLT+AL+TGK
Sbjct 65 LDLLARDGDGPDARYRNTAETARYLDEASPEYQGGLLKIWDQRNYRFWADLTDALQTGKP 124
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
Q+E+KQTGRPFFE +YADPRRLE F+ AMD+ASRRN ELL KRFPF+RY LCDVG A+G
Sbjct 125 QNEIKQTGRPFFETVYADPRRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANG 184
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
LLSR AAAHPHLQC+SFDLPAVT+I RRKL+ +GLG+RV+A +GDF ADPLP+ADVITM
Sbjct 185 LLSRTAAAAHPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVITM 244
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
GQILHDWNLD KQ+L+AKAYEAL + GAFI IETLIDDARR+NT GLMMSLNMLIEFGDA
Sbjct 245 GQILHDWNLDGKQRLIAKAYEALPEGGAFIAIETLIDDARRKNTAGLMMSLNMLIEFGDA 304
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ ADFR WCG AGFRSFEVI LA GSSAAVAYK
Sbjct 305 FDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK 340
>gi|118616484|ref|YP_904816.1| methyltransferase/methylase [Mycobacterium ulcerans Agy99]
gi|118568594|gb|ABL03345.1| methyltransferase/methylase [Mycobacterium ulcerans Agy99]
Length=340
Score = 556 bits (1433), Expect = 2e-156, Method: Compositional matrix adjust.
Identities = 267/335 (80%), Positives = 297/335 (89%), Gaps = 0/335 (0%)
Query 5 PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSL 64
PDRIMAIG GYGPSKVLLTAVGLGLFTELGD AMTA+A+A+ LGL+ RPA DFLDALVSL
Sbjct 6 PDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQALAELLGLVPRPATDFLDALVSL 65
Query 65 DLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQ 124
DLLARDGDGP + YRNT ETA +LDEA P Y GGLLKIW++RNYRFWADLT+AL+TGK Q
Sbjct 66 DLLARDGDGPDARYRNTAETARYLDEASPEYQGGLLKIWDQRNYRFWADLTDALQTGKPQ 125
Query 125 SEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGL 184
+E+KQTGRPFFE +YADPRRLE F+ AMD+ASRRN ELL KRFPF+RY LCDVG A+GL
Sbjct 126 NEIKQTGRPFFETVYADPRRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGL 185
Query 185 LSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMG 244
LSR AAAHPHLQC+SFDLPAVT+I RRKL+ +GLG+RV+A +GDF ADPLP+ADVITMG
Sbjct 186 LSRTAAAAHPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVITMG 245
Query 245 QILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAF 304
QILHDWNLD KQ+L+AKAYEAL + GAF IETLIDDARR+NT GLMMSLNMLIEFGDAF
Sbjct 246 QILHDWNLDGKQRLIAKAYEALPEGGAFTAIETLIDDARRKNTAGLMMSLNMLIEFGDAF 305
Query 305 DYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
DY+ ADFR WCG AGFRSFEVI LA GSSAAVAYK
Sbjct 306 DYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK 340
>gi|254432782|ref|ZP_05046485.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Cyanobium sp. PCC 7001]
gi|197627235|gb|EDY39794.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Cyanobium sp. PCC 7001]
Length=362
Score = 421 bits (1082), Expect = 9e-116, Method: Compositional matrix adjust.
Identities = 209/338 (62%), Positives = 243/338 (72%), Gaps = 0/338 (0%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
E P I+AI GYG SK LL+AVGLGL T+L MT E IA GL RP DFLD L
Sbjct 22 EPDPSAILAIASGYGVSKALLSAVGLGLHTQLAAGPMTCEQIAAAFGLQGRPTRDFLDLL 81
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
VS+D+LAR+GD P + Y NTP TA FLD ++P Y GGL +IW R+YRFWADLTEAL++G
Sbjct 82 VSVDMLAREGDAPEALYGNTPATARFLDRSQPEYIGGLPEIWELRDYRFWADLTEALRSG 141
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ Q+E K G PFFEA+Y DP RLEAFM AM+ +S RN + LA+ FPF Y L D+G A
Sbjct 142 RPQNEAKHAGTPFFEAMYGDPERLEAFMNAMNGSSLRNFQALARAFPFGSYATLTDIGGA 201
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
D LL R VAA H + CVSFDLP VT IA R++ A GLGER+ A +GDF DP P A +I
Sbjct 202 DALLCREVAAVHSGIHCVSFDLPPVTPIADRRIAAAGLGERIHAVSGDFFVDPWPPAQLI 261
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
TMG ILHDWNL+RKQ L+ KAY+AL + GA I IE IDDARR NT GL MSL MLIEFG
Sbjct 262 TMGMILHDWNLERKQTLIRKAYDALPEGGALIAIEAFIDDARRHNTFGLFMSLMMLIEFG 321
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
DAFD++AA+FR WC AGF FE IPL G SSA VAYK
Sbjct 322 DAFDFTAAEFRQWCAAAGFSRFETIPLDGPSSAVVAYK 359
>gi|220905879|ref|YP_002481190.1| O-methyltransferase family 2 [Cyanothece sp. PCC 7425]
gi|219862490|gb|ACL42829.1| O-methyltransferase family 2 [Cyanothece sp. PCC 7425]
Length=353
Score = 390 bits (1001), Expect = 2e-106, Method: Compositional matrix adjust.
Identities = 188/335 (57%), Positives = 234/335 (70%), Gaps = 0/335 (0%)
Query 5 PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSL 64
P I+ +G G+ SK+LLTAV LG+FT LGD AM E + L L R DF DALV+L
Sbjct 19 PSHILQVGFGFWSSKILLTAVKLGVFTTLGDRAMAGEELGKALDLHPRAIFDFFDALVAL 78
Query 65 DLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQ 124
L R+G+G + YRNT TA +LD+ +P+Y GG+L++ N+R + FW+DL ALKTGK Q
Sbjct 79 GFLDREGNGVAARYRNTAITAQYLDKHQPSYIGGILEMANDRLFNFWSDLEPALKTGKPQ 138
Query 125 SEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGL 184
+E+K +P FE LYADP RLE F+ AM SR N + A +F F + LCDVG A GL
Sbjct 139 NEIKHKQKPMFEELYADPSRLEQFIDAMTGISRGNFQSFAAQFDFSSHTTLCDVGGAAGL 198
Query 185 LSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMG 244
LS++V HPH+QC+SFDLP V IAR+ + GL R+Q +GDFL+ LP ADVITMG
Sbjct 199 LSQLVVQQHPHMQCISFDLPQVEPIARQSIEKAGLAARIQVVSGDFLSASLPKADVITMG 258
Query 245 QILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAF 304
ILHDWNL+ K+ L+ AYEAL + GA + IE LIDD RREN GL+MSLNMLIEFGDAF
Sbjct 259 MILHDWNLEIKKHLIHLAYEALPENGALVAIENLIDDDRRENAFGLLMSLNMLIEFGDAF 318
Query 305 DYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
D++ ADF WC EAGFR +EVI L G SAA+AYK
Sbjct 319 DFTGADFWKWCQEAGFRRYEVIHLVGPCSAAIAYK 353
>gi|115373042|ref|ZP_01460345.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Stigmatella aurantiaca DW4/3-1]
gi|310821868|ref|YP_003954226.1| tetracenomycin polyketide synthesis 8-o-methyl transferase tcmo
[Stigmatella aurantiaca DW4/3-1]
gi|115369954|gb|EAU68886.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Stigmatella aurantiaca DW4/3-1]
gi|309394940|gb|ADO72399.1| Tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Stigmatella aurantiaca DW4/3-1]
Length=341
Score = 389 bits (998), Expect = 4e-106, Method: Compositional matrix adjust.
Identities = 188/335 (57%), Positives = 232/335 (70%), Gaps = 0/335 (0%)
Query 5 PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSL 64
P RIM IG GY SK LLTAV LG+FT+LG ++T + R+ L R DF D+LV+L
Sbjct 7 PSRIMQIGTGYWASKTLLTAVELGVFTQLGQGSLTGPELGKRMELHPRTIYDFFDSLVAL 66
Query 65 DLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQ 124
LL R+GDGP YRNTPET LD P Y GG+L+++N R YRFW DL+EAL+TG+AQ
Sbjct 67 GLLEREGDGPTGRYRNTPETKALLDRNSPDYMGGILEMFNSRLYRFWGDLSEALRTGEAQ 126
Query 125 SEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGL 184
SE+K TG+ + L++DP RLE F AM SRRN A++F RYR LCDVG +
Sbjct 127 SEIKHTGKSMYTELFSDPERLEQFTRAMSGISRRNFVAFAEKFDLSRYRTLCDVGGSSAE 186
Query 185 LSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMG 244
LS VA HPHL CVSFDLP + IA+R + GL R+ GDFL +PLP ADVITMG
Sbjct 187 LSISVAQRHPHLACVSFDLPVLKPIAQRAIDRAGLTGRITPVGGDFLHEPLPKADVITMG 246
Query 245 QILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAF 304
ILH+W+L++++ L+ AYEAL ++GAF+ IE IDDARR+N GL+MSL MLIEFGDA
Sbjct 247 MILHNWSLEKRKHLIRLAYEALPEDGAFVAIEHFIDDARRQNAFGLLMSLTMLIEFGDAS 306
Query 305 DYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
D++ ADFRGWC EAGFR FE I L +A VAYK
Sbjct 307 DFTGADFRGWCSEAGFRRFETIALTDPGAAVVAYK 341
>gi|197104541|ref|YP_002129918.1| methyltransferase/methylase [Phenylobacterium zucineum HLK1]
gi|196477961|gb|ACG77489.1| methyltransferase/methylase [Phenylobacterium zucineum HLK1]
Length=344
Score = 377 bits (969), Expect = 1e-102, Method: Compositional matrix adjust.
Identities = 199/337 (60%), Positives = 239/337 (71%), Gaps = 0/337 (0%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
++PDR+ +G G+ SK LL+AV LG+F+ L + M+A + RLGL R DFLD LV
Sbjct 8 VAPDRVYEVGMGFWASKTLLSAVELGVFSVLAERPMSAAELEARLGLHPRATADFLDGLV 67
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
++ +L R G G + Y NTPETA FLD A P Y GGLL++ N R Y FW DLT AL+TG+
Sbjct 68 AIGMLDRAGAGASALYANTPETAVFLDRASPRYVGGLLEMANARLYPFWGDLTNALRTGR 127
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
Q+E +TG+P FE LYADP RLE FM AM AS RN E A+RF F +R L D+G A
Sbjct 128 PQNEAARTGKPVFEELYADPARLEQFMDAMTGASLRNFEAFAERFDFAPHRSLADIGGAT 187
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
GLLS IVA HPHL C ++DLP V IA R++ EGL RV+A A DFLA+ LP ADVIT
Sbjct 188 GLLSCIVARRHPHLACATYDLPVVGPIAERRIAREGLAGRVRAGALDFLAEELPKADVIT 247
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
MG ILHDWNL+ K+ L+AKAY AL + GA + IE +IDD RR N GLMMSLNMLIEFGD
Sbjct 248 MGMILHDWNLEHKKMLIAKAYRALPEGGALVAIENIIDDERRTNAYGLMMSLNMLIEFGD 307
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
AFD++ ADF GWC EAGF EVIPLAG +SAAVAYK
Sbjct 308 AFDFTGADFAGWCREAGFSRCEVIPLAGAASAAVAYK 344
>gi|254431102|ref|ZP_05044805.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Cyanobium sp. PCC 7001]
gi|197625555|gb|EDY38114.1| tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO
[Cyanobium sp. PCC 7001]
Length=336
Score = 324 bits (831), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 169/337 (51%), Positives = 216/337 (65%), Gaps = 4/337 (1%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
LSP+ I+ G + SK LL+AV LGLF+EL + + EA+ RL L R A DFLDALV
Sbjct 4 LSPEAILQTGLAFWASKTLLSAVELGLFSELANGPLPLEALMARLALHPRSARDFLDALV 63
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
+L L+RD G Y NTP+TA FLD A+PTY GGLL++ N R Y W L+EAL++G+
Sbjct 64 ALGFLSRDASG----YANTPDTALFLDRAKPTYVGGLLEMANHRLYPAWGHLSEALRSGE 119
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
Q+E+K G FE LYADP+ L+ F+AAM SR + +A+ FP++ YR DVG A
Sbjct 120 PQNELKSGGPGLFEVLYADPKALKEFLAAMSGISRGANQTIARTFPWQPYRTFVDVGTAQ 179
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L+ +A A PHL+ + FDLP V + + + GLGER+Q AGDF PLP+ADV+
Sbjct 180 GDLAVQIALAQPHLRGIGFDLPPVEPVFTSYVESHGLGERLQFTAGDFFQQPLPSADVVL 239
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
MG ILHDW+L K+ L+ KAY+AL GA +V E +IDD R N GL+MSLNMLIE
Sbjct 240 MGHILHDWDLPTKRMLIGKAYDALPPGGALVVYEAIIDDDRSRNAFGLLMSLNMLIETSG 299
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDYS AD GW EAGF S V PL G + + K
Sbjct 300 GFDYSGADCMGWMREAGFSSTRVEPLVGPDAMVIGVK 336
>gi|302039074|ref|YP_003799396.1| o-methyltransferase [Candidatus Nitrospira defluvii]
gi|300607138|emb|CBK43471.1| O-methyltransferase, family 2 [Candidatus Nitrospira defluvii]
Length=337
Score = 315 bits (807), Expect = 7e-84, Method: Compositional matrix adjust.
Identities = 170/338 (51%), Positives = 216/338 (64%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
+LSPDRIM +G G+ SK LL+AV LGLFTEL ++ A+A+A RL L R A DF DAL
Sbjct 5 QLSPDRIMQLGFGFWGSKTLLSAVELGLFTELAKRSLDAKALAKRLELHPRSARDFFDAL 64
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L +L R G+ Y NT E+A FLD A+P+Y GG+L++ N R Y FW LTE L+TG
Sbjct 65 VALGMLKR----VGTRYANTSESALFLDRAKPSYVGGILEMANVRLYPFWGSLTEGLRTG 120
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
K Q+EVK TG FF LYADP+RLE F+ AM S+ +A +FP+ R+R D+GCA
Sbjct 121 KPQNEVK-TGEDFFGTLYADPQRLEGFLKAMTGLSQGTARAIAAKFPWTRHRSFVDIGCA 179
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G ++ +A AH HL DLP V I + L +R+ AGDF D LP ADV+
Sbjct 180 QGGVAAEIALAHKHLSGQGMDLPVVRPIFEAYAKSRTLEKRLTFHAGDFFNDALPKADVL 239
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L+ K L+ KAYEAL GA IV E LIDDAR++N GL+MSLNMLIE
Sbjct 240 IMGHILHDWDLNEKMMLLRKAYEALPSGGALIVHEALIDDARKQNAFGLLMSLNMLIETP 299
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FD++ AD W +AGF+ +V L G S +A K
Sbjct 300 GGFDFTGADCIQWMKKAGFKRTKVEKLTGPDSMVIAIK 337
>gi|296445285|ref|ZP_06887244.1| O-methyltransferase family 2 [Methylosinus trichosporium OB3b]
gi|296257240|gb|EFH04308.1| O-methyltransferase family 2 [Methylosinus trichosporium OB3b]
Length=336
Score = 305 bits (780), Expect = 9e-81, Method: Compositional matrix adjust.
Identities = 169/338 (50%), Positives = 208/338 (62%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
+LSP++I+ +G G+ +K LL+AV LGLFT L + AE + RLGL R A+DF DAL
Sbjct 4 QLSPEKILGLGFGFWNAKTLLSAVELGLFTILAEAPADAETLRSRLGLHPRSALDFFDAL 63
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L LL RD YRNT E A FLD A+P+Y G +L++ N R + W LTEALKTG
Sbjct 64 VALGLLERDN----GLYRNTAEAALFLDRAKPSYVGQILELANARLFASWDRLTEALKTG 119
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ QSE + FF ALYADP RL F+ AM S + +A++FP+ +Y DVG A
Sbjct 120 RPQSE-NAAEKDFFAALYADPARLRGFLTAMSGISAGPAKAIAEKFPWTKYGSFVDVGSA 178
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G++ VA AHPHL FDLP V I + A GL +RV GDF D LP ADVI
Sbjct 179 QGMVPATVARAHPHLIGAGFDLPQVKPIFDDFIAANGLSDRVTFRGGDFFRDALPGADVI 238
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L+ K+ L+A AY AL K GA IV E LIDD RR N GL+MSLNMLIE
Sbjct 239 VMGHILHDWDLEEKRHLLANAYAALPKGGALIVYEALIDDERRTNAFGLLMSLNMLIETP 298
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ AD +GW EAGF V L G S + K
Sbjct 299 GGFDYTGADCQGWMREAGFAETRVEHLLGPDSMVIGVK 336
>gi|220925549|ref|YP_002500851.1| O-methyltransferase family 2 [Methylobacterium nodulans ORS 2060]
gi|219950156|gb|ACL60548.1| O-methyltransferase family 2 [Methylobacterium nodulans ORS 2060]
Length=338
Score = 305 bits (780), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 160/338 (48%), Positives = 212/338 (63%), Gaps = 4/338 (1%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEA-IADRLGLLKRPAIDFLDAL 61
++PD+I+ +G + SK LL+A+ LGLFT L ++ A + + L L +R A DFLDAL
Sbjct 4 IAPDKILQLGSAFWGSKTLLSAIELGLFTHLAQRGPSSLAEMREGLSLHERSARDFLDAL 63
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L +L R DG Y NTPET +LD +P+Y GG+L++ N R YRFW +LT+ALKTG
Sbjct 64 VALGMLQRLPDG---RYANTPETELYLDRTKPSYVGGILEMMNGRLYRFWGNLTDALKTG 120
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
Q+E + F A+YADP RLE F+ AM S +A FP+ Y+ D+GCA
Sbjct 121 LPQNEAQHGEPDLFAAVYADPARLELFLGAMTGISLPTARAMATAFPWREYQTFADIGCA 180
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L+ +A AH HL FDLP V+ + R + GL +R+ G+F DPLP+ DV+
Sbjct 181 QGGLTVEIARAHSHLTGYGFDLPIVSPVFERYVAQHGLDQRLTFQPGNFFQDPLPSVDVL 240
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L++K+ L+ KAY+AL GA IV + +IDD RR+N GL+MSLNMLIE
Sbjct 241 VMGHILHDWSLEQKKMLLRKAYDALPSGGALIVYDAMIDDERRQNAFGLLMSLNMLIETP 300
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ AD RGW EAGFR V L G S AV K
Sbjct 301 AGFDYTGADCRGWMTEAGFRDVRVEHLQGPYSMAVGRK 338
>gi|223937003|ref|ZP_03628911.1| O-methyltransferase family 2 [bacterium Ellin514]
gi|223894284|gb|EEF60737.1| O-methyltransferase family 2 [bacterium Ellin514]
Length=362
Score = 304 bits (779), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 161/338 (48%), Positives = 206/338 (61%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
++PD+I I G+ SK LL+AV LGLFTEL A ++ +LGL +R A DF D L
Sbjct 30 HITPDKIGQIAFGFASSKALLSAVELGLFTELAKSPGDAASLTAKLGLNERAARDFFDTL 89
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L +L R G Y NTPE +LD A+PTY GGLL++ N R Y FW LTEAL+TG
Sbjct 90 VALGMLDRKG----GFYSNTPEADLYLDRAKPTYMGGLLEMMNARLYAFWGSLTEALRTG 145
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
K Q+E+K G F E LY++P RLEAF+ AM S +A++FP++ Y+ DVGCA
Sbjct 146 KPQNEIKAGGNAF-EVLYSNPERLEAFLKAMTGISLGTGRAIAEKFPWDNYKTFVDVGCA 204
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L VA H HL + +DL V I R + GL +R++ GDF DPLP DV+
Sbjct 205 QGALPVQVALKHGHLTGLGYDLECVGPIYERYIRTNGLSDRLKFAPGDFFKDPLPKTDVL 264
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDWNL+ K+ L+ KAY+AL GA ++ E +IDD RR N GL+MSLNMLIE
Sbjct 265 VMGHILHDWNLEEKKMLLKKAYDALQPGGAVLIYEAIIDDERRNNVFGLIMSLNMLIETT 324
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ A+ W EAGFR V L G S + K
Sbjct 325 GGFDYTGAECCQWMREAGFRETRVEHLIGPDSMVIGIK 362
>gi|332708639|ref|ZP_08428612.1| O-methyltransferase [Lyngbya majuscula 3L]
gi|332352595|gb|EGJ32162.1| O-methyltransferase [Lyngbya majuscula 3L]
Length=339
Score = 304 bits (778), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 158/338 (47%), Positives = 209/338 (62%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
+L PD+++ +G + SK L+AV LG+FTEL +MTA + ++L L R A DFLDAL
Sbjct 7 QLVPDKLLELGFAFSASKTFLSAVELGVFTELAQSSMTAAELTEKLALHPRSARDFLDAL 66
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L++L R D Y NTPE+ FLD ++P+Y GG L++ N R Y FW LTE L+TG
Sbjct 67 VALNVLERCND----RYSNTPESDLFLDRSKPSYIGGCLEMCNSRLYGFWGSLTEGLRTG 122
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ Q+E K G FF LY DP RL+ F+ AM S + +A++FP+E+++ D+G A
Sbjct 123 QPQNEAKN-GEDFFGTLYGDPARLKIFLEAMSGISMGVAKAIAEKFPWEKFQTFIDIGTA 181
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L VA +H HL FDLP V I + + GL +R+ GDF D LP+ADV+
Sbjct 182 QGQLPVTVALSHDHLHGGGFDLPVVRPIYEEYVASRGLSQRLDFHGGDFFQDMLPSADVL 241
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDWNL++K L+AKAYEAL GA IV + LIDD R +N GL+MSLNMLIE
Sbjct 242 VMGHILHDWNLEQKHLLIAKAYEALPTGGALIVYDALIDDQRCQNRFGLLMSLNMLIETF 301
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ AD W + GF+ PL G S AV K
Sbjct 302 GGFDYTGADCCAWMDKVGFKDTYTKPLVGAYSMAVGIK 339
>gi|73539379|ref|YP_299746.1| O-methyltransferase family protein [Ralstonia eutropha JMP134]
gi|72122716|gb|AAZ64902.1| O-methyltransferase, family 2 [Ralstonia eutropha JMP134]
Length=352
Score = 300 bits (768), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 158/338 (47%), Positives = 210/338 (63%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
EL+PDR++ +G G+ SK +L+AV LG+FT L + A + LGL +R A+DFLDAL
Sbjct 20 ELTPDRLLQLGMGFWASKTMLSAVELGVFTRLAAGPLGAAELISALGLHRRSALDFLDAL 79
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L LL R+ YRNTP+TA FLD A+P+Y G LL++ N R Y FW LTEAL+TG
Sbjct 80 VALKLLEREQ----GKYRNTPDTALFLDAAKPSYVGDLLEMANTRLYPFWGSLTEALRTG 135
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ Q+E K+ G FEA+Y D L F+ AM S + +A++FP++ Y D+G A
Sbjct 136 QPQNEAKRGGN-LFEAVYHDEHALRRFLRAMTGVSLGAAKAMAQKFPWQNYSTFIDIGTA 194
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L +A AHPHL+ FDLPAV + + + GL ER++ GDF DP P ADV+
Sbjct 195 QGALPVQIALAHPHLRGGGFDLPAVGPVFEEYVVSHGLQERLRFQPGDFFKDPCPTADVL 254
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L +K +L+ K + AL EG IV + +IDD RR+N GL+MSLNMLIE
Sbjct 255 VMGHILHDWDLGQKLELLKKCHAALPDEGCLIVYDAVIDDERRQNAFGLLMSLNMLIETP 314
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ A W EAGF V PLAG S + +
Sbjct 315 GGFDYTGAQCCAWMKEAGFTQVRVEPLAGPDSMVIGIR 352
>gi|295676181|ref|YP_003604705.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1002]
gi|295436024|gb|ADG15194.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1002]
Length=353
Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 157/338 (47%), Positives = 208/338 (62%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
E SP+R++ +G G+ +K LL+AV LG+FT L AE + + LGL R A+DFLDAL
Sbjct 21 EPSPERLLQLGMGFWATKTLLSAVELGVFTRLAIAPQNAEELREALGLHPRSALDFLDAL 80
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L+LL R+ YRNT + FLD+A+P Y GGLL++ N R Y FW LTEAL+TG
Sbjct 81 VALNLLEREN----GKYRNTQDAELFLDKAKPGYVGGLLEMANARLYPFWGLLTEALRTG 136
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
Q+EVK G PF +ALY D L F+ AM S + +A++FP++ YR D+G A
Sbjct 137 MPQNEVKHGGNPF-DALYRDEPSLRGFLQAMTGVSLGPAKAMAQKFPWQNYRTFLDIGAA 195
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L +A AHPHL+ FDLP V + + + + GL ER+ +GDF DP P+ADV+
Sbjct 196 QGALPVEIALAHPHLRGGGFDLPVVGPLFEQYVASHGLQERLSFHSGDFFKDPCPSADVL 255
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L +K +L+ K + AL G IV + +IDD RR+N GL+MSLNMLIE
Sbjct 256 VMGHILHDWDLAQKMELLTKCHAALPPGGCLIVYDAVIDDERRQNAFGLLMSLNMLIETP 315
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ A W E GF V PLAG S + K
Sbjct 316 GGFDYTGAQCCAWMKEVGFTQVRVEPLAGPDSMVIGTK 353
>gi|323138579|ref|ZP_08073647.1| O-methyltransferase family 2 [Methylocystis sp. ATCC 49242]
gi|322396213|gb|EFX98746.1| O-methyltransferase family 2 [Methylocystis sp. ATCC 49242]
Length=336
Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 161/336 (48%), Positives = 208/336 (62%), Gaps = 5/336 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
SP++++A+G + +K LL+AV LG+F L D + +LGL +R A DFLDALV+
Sbjct 6 SPEKLLALGMSFWNAKTLLSAVELGVFDALADGPADLSTLTKKLGLHERSARDFLDALVA 65
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
+ +L R+ YRNTPET FL RP+Y GGLL++ N R Y W +LTEALKTG+
Sbjct 66 MKMLDRES----GQYRNTPETDFFLVRGRPSYVGGLLEMANARLYSSWGNLTEALKTGQR 121
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
QSE K+ G F ALYADP RL F+AAM S +A++FP+ Y+ DVG A G
Sbjct 122 QSENKEEGD-LFGALYADPDRLRGFLAAMSGVSAGAARAIAEKFPWSDYKTFIDVGAAQG 180
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
++ VA AH HL FDLPAV I + A GL +R++ GDF D LPAADVI M
Sbjct 181 MVPVTVARAHAHLSGGGFDLPAVGPIFNDFVAANGLADRLRFHPGDFFNDALPAADVIIM 240
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G ILHDW+L +K+ L+ KA++AL GA IV E +IDD RR+N GL+MSLNMLIE
Sbjct 241 GHILHDWDLAQKRMLLKKAHDALPDGGALIVYEAIIDDDRRQNAFGLLMSLNMLIETAGG 300
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FD++ AD W EAGF V L G S + +K
Sbjct 301 FDFTGADCESWMKEAGFAKTRVEHLVGPDSMVIGFK 336
>gi|311745287|ref|ZP_07719072.1| tetracenomycin polyketide synthesis 8-o-methyltransferase [Algoriphagus
sp. PR1]
gi|126577819|gb|EAZ82039.1| tetracenomycin polyketide synthesis 8-o-methyltransferase [Algoriphagus
sp. PR1]
Length=346
Score = 296 bits (759), Expect = 3e-78, Method: Compositional matrix adjust.
Identities = 150/339 (45%), Positives = 204/339 (61%), Gaps = 4/339 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELG---DEAMTAEAIADRLGLLKRPAIDFLDA 60
+P+ I+ IG G+ K LLTAV LFT+L D+ A L R DF+D
Sbjct 9 TPENILKIGSGFMACKALLTAVKFDLFTKLSAHPDQKALALKKQLDLNCTDRHFYDFMDG 68
Query 61 LVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKT 120
L L L R G + Y N+ +T FLD+ +P+Y GG+L++ N R Y FW +L E LKT
Sbjct 69 LYGLGFLTRTGILETALYSNSQDTEVFLDKNKPSYIGGILEMMNARLYGFWGNLEEGLKT 128
Query 121 GKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
G Q+E K G FE +Y +P LE F+ M N AK+F F +++ L D G
Sbjct 129 GTPQNEAKN-GVNIFEEIYKEPELLETFVNGMTGVQIGNFMAFAKQFDFSKFKTLTDAGG 187
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
+ G LS +VA +PH+ CV+FDLP + IA + L +RV++ +GDF + +P AD+
Sbjct 188 SAGYLSLMVAQENPHMSCVTFDLPPLNPIANATIKKFNLADRVKSQSGDFFMEAIPKADM 247
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
I MG ILHDWN K +L+ KAY++L +EG F+ IE +ID R+ N GLMMSLNMLIE
Sbjct 248 IVMGNILHDWNKKEKIKLMQKAYDSLPEEGVFVAIENIIDQERKHNVFGLMMSLNMLIET 307
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ DF+ W E GF+SFE++PLAG +SAA+AYK
Sbjct 308 EGGFDYTFDDFQSWGKEVGFKSFEILPLAGPASAAIAYK 346
>gi|87302194|ref|ZP_01085019.1| O-methyltransferase, family 2 [Synechococcus sp. WH 5701]
gi|87283119|gb|EAQ75075.1| O-methyltransferase, family 2 [Synechococcus sp. WH 5701]
Length=337
Score = 293 bits (749), Expect = 3e-77, Method: Compositional matrix adjust.
Identities = 158/338 (47%), Positives = 204/338 (61%), Gaps = 4/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
+L+P++I+ G + SK LL+AV +GLFTEL + + ++ RLGL R A DFLDAL
Sbjct 4 QLNPEKILQTGLAFWASKTLLSAVEMGLFTELSSGPESLDKLSGRLGLHPRSARDFLDAL 63
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L L R G Y NTPET FLD +P+Y GG+L++ N R Y FW +LTEAL+TG
Sbjct 64 VALGFLTRTG----GEYSNTPETELFLDRNKPSYLGGILEMANHRLYPFWNNLTEALRTG 119
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ Q+E K G FE LYADP RL+ F+AAM S +AK FP++ YR DVG A
Sbjct 120 QPQNEAKSGGPELFEILYADPARLKEFLAAMSGISHGANMKIAKTFPWKEYRTFVDVGTA 179
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L+ + A+PHL+ FDLP V I + G+ +R+ G F +P ADVI
Sbjct 180 QGDLAAQIILANPHLRGEGFDLPEVAPIFEEYIEGLGIKDRLTFVPGSFFTQDIPPADVI 239
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L K+ L+ KA++A+ GA +V E +IDD R +N GLMMSLNMLIE
Sbjct 240 LMGHILHDWDLPTKKMLIRKAFDAVPTGGALVVYEAIIDDDRSKNAFGLMMSLNMLIETP 299
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ AD W EAGF S V L G S V K
Sbjct 300 GGFDYTGADCVRWMLEAGFTSTWVEELVGPDSMVVGIK 337
>gi|116626250|ref|YP_828406.1| O-methyltransferase family protein [Candidatus Solibacter usitatus
Ellin6076]
gi|116229412|gb|ABJ88121.1| O-methyltransferase, family 2 [Candidatus Solibacter usitatus
Ellin6076]
Length=337
Score = 292 bits (747), Expect = 7e-77, Method: Compositional matrix adjust.
Identities = 156/336 (47%), Positives = 205/336 (62%), Gaps = 4/336 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
+PD I+ +G G+ PSKVLL+AV + LFT+L + E I R+GL R A DFLD LV+
Sbjct 6 TPDSILQVGLGFWPSKVLLSAVEMELFTDLAKGPQSLETIQGRMGLHARAARDFLDTLVA 65
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
L L R DG Y NT T FLD+ +P+Y GG+L++ N+R Y FW LTEAL+TG+
Sbjct 66 LGFLQR-ADG---QYSNTAATDLFLDKHKPSYIGGILEMANQRLYGFWGHLTEALRTGQP 121
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
Q+EV+ G FE+LYADP RL++F+AAM S +A +FP+ Y D G A G
Sbjct 122 QNEVRNGGSALFESLYADPARLKSFLAAMSGISHGANMKIASQFPWSGYTSFVDAGTAQG 181
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
L+ +A A+PHL + FDL V I G+ R++ G FL P+P ADV+ M
Sbjct 182 DLAVQIALANPHLSGIGFDLAEVGPIFEEYAERNGVSGRLRFHGGSFLEQPIPHADVVLM 241
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G ILHDW L K+ L+ KAY+A+ GA +V E++IDD R +N GLMMSLNMLIE
Sbjct 242 GHILHDWGLPEKRMLIRKAYDAVPDGGALVVYESIIDDDRSKNAFGLMMSLNMLIETRAG 301
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ AD +GW EAGFR V L G S + +
Sbjct 302 FDYTGADCQGWMKEAGFRETRVEHLLGPDSMVIGIR 337
>gi|171913856|ref|ZP_02929326.1| O-methyltransferase, family 2 [Verrucomicrobium spinosum DSM
4136]
Length=335
Score = 291 bits (746), Expect = 9e-77, Method: Compositional matrix adjust.
Identities = 156/336 (47%), Positives = 203/336 (61%), Gaps = 5/336 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
+PDRI G + PSKVLL+AV + +FTEL + RLGL R DFLD LV+
Sbjct 5 TPDRIFQTGLAFWPSKVLLSAVEMEVFTELAKHPGDLATVQGRLGLHPRGGRDFLDTLVA 64
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
L L R+G YRNTPET FLD+ +P+Y GG+L++ N R ++FW LTEAL+TG
Sbjct 65 LGFLVREG----GVYRNTPETDLFLDKNKPSYIGGILEMANSRLFKFWGSLTEALRTGLR 120
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
Q+E K G F LYADP RL+ F+ AM SR +A++FP+ +Y D G A G
Sbjct 121 QNEGKH-GDDMFATLYADPARLKEFLRAMSGVSRGANLAIARQFPWAQYNSFVDAGTAQG 179
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
L+ VA A PH++ + FDLP V I T G+ +R+ G F D LP DV+ M
Sbjct 180 DLAVQVALAQPHVRGIGFDLPEVAPIFEDYATQAGVADRLSFQGGSFFTDDLPKVDVVMM 239
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G ILHDW+L++K+ L+ +AYEA+ + GA IV +++IDD R +N GLMMSLNML+E
Sbjct 240 GHILHDWDLEQKKLLLRRAYEAVPEGGAVIVYDSIIDDDRSQNAFGLMMSLNMLVETDGG 299
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDYS AD RGW E GF+ V L G S V K
Sbjct 300 FDYSGADCRGWMEEIGFKDIRVEHLVGPDSMVVGIK 335
>gi|209518561|ref|ZP_03267381.1| O-methyltransferase family 2 [Burkholderia sp. H160]
gi|209501011|gb|EEA01047.1| O-methyltransferase family 2 [Burkholderia sp. H160]
Length=349
Score = 290 bits (742), Expect = 3e-76, Method: Compositional matrix adjust.
Identities = 158/336 (48%), Positives = 207/336 (62%), Gaps = 5/336 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
S ++++ +G G+ SK LL+AV L LFT LG A + + L L R A+DFLDALV+
Sbjct 19 STEKLLQLGMGFWGSKALLSAVELDLFTVLGRGPRNATQLMEELRLHPRSALDFLDALVA 78
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
L +L RD DG YRNT ET FLD A+P + GGLL + N R Y FW LTEAL+TG+
Sbjct 79 LGVLDRD-DG---LYRNTAETGAFLDRAKPGFMGGLLLMANNRLYPFWGSLTEALRTGQP 134
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
Q+E KQ G PF +A+Y D L F+ AM S+ + +A++FP++ YR DVG A G
Sbjct 135 QNEAKQGGNPF-DAIYRDEPVLREFLGAMSGVSQGPAKAIARKFPWQNYRSFVDVGTAQG 193
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
L VA H HL V FDLPAV + + L ER++ GDF + P+ADV+ M
Sbjct 194 ALMVEVARTHEHLTGVGFDLPAVGPVFNDYIAQNDLQERIRFHPGDFFKEAFPSADVLVM 253
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G ILHDWNL++K++L+AK+Y+AL G IV + +IDD RR N GL+MSLNMLIE
Sbjct 254 GHILHDWNLEQKRELLAKSYKALPAGGCLIVYDAVIDDERRRNAFGLLMSLNMLIETPGG 313
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ R W EAGFR V PL G +S + +
Sbjct 314 FDYTGKQCREWMTEAGFREVRVEPLVGPTSMIIGVR 349
>gi|82703424|ref|YP_412990.1| putative transcriptional regulator [Nitrosospira multiformis
ATCC 25196]
gi|82411489|gb|ABB75598.1| putative transcriptional regulator [Nitrosospira multiformis
ATCC 25196]
Length=392
Score = 286 bits (732), Expect = 3e-75, Method: Compositional matrix adjust.
Identities = 152/338 (45%), Positives = 207/338 (62%), Gaps = 4/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
+L+P+ I+ G + P+K LL+AV LG+FT L +++ +A+A++ GL R A DFLDAL
Sbjct 59 QLTPENILKTGMAFWPAKTLLSAVELGVFTRLAQGSLSLDALAEQAGLHPRGARDFLDAL 118
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L L R+GD Y NT ET FLD +P+Y GG+L++ N R Y W+DLT+AL TG
Sbjct 119 VALGFLDREGD----RYSNTSETDLFLDRNKPSYIGGILEMANRRLYPIWSDLTQALLTG 174
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
K Q+E++ FE LYADP L+ F+AAM SR +A+ FP+ Y DVG A
Sbjct 175 KPQNEIRTGEADLFEKLYADPAGLKEFLAAMTGVSRAANMTIARAFPWHGYHTFVDVGTA 234
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L+ +A A+ HL+ + +D P V I + + +RV G+F + LP ADV+
Sbjct 235 QGDLAVQIALANSHLRGMGYDRPEVGPIFEQYAQTANVADRVSFVPGNFFEEDLPQADVV 294
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+L K+ L KA++AL GAF+V E+LIDD R +N GLMMSLNMLIE
Sbjct 295 LMGHILHDWDLSTKKMLTRKAFDALPAGGAFVVYESLIDDDRSQNAFGLMMSLNMLIETP 354
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FD++ AD W EAGF + V PL G S + K
Sbjct 355 GGFDFTGADCMAWMKEAGFSNTRVEPLVGTDSMVIGIK 392
>gi|307726176|ref|YP_003909389.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1003]
gi|307586701|gb|ADN60098.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1003]
Length=351
Score = 286 bits (731), Expect = 5e-75, Method: Compositional matrix adjust.
Identities = 154/336 (46%), Positives = 201/336 (60%), Gaps = 5/336 (1%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
SP+R++ +G + SK LL+AV LG+FT+L +A A+ + LGL R A+DFLDALV+
Sbjct 21 SPERLLHLGMAFWGSKTLLSAVELGVFTQLASGPRSAAALTESLGLHARSALDFLDALVA 80
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKA 123
L +L R Y NTP+ FLD+A+P+Y GGLL++ N R Y FW LTEAL+TG
Sbjct 81 LSVLERHE----GTYSNTPDADLFLDKAKPSYVGGLLEMANARLYPFWGSLTEALRTGLP 136
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
Q+E K G F+A+Y D L F+ AM S +A+RFP+ YR D+G A G
Sbjct 137 QNEAKSGGN-LFDAIYRDEASLRGFLRAMSGVSLGAARAIAQRFPWSEYRSFIDIGTAQG 195
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
L VA AHPHL FDLP V + + A GL +R+Q GDF DP P+ADV+ M
Sbjct 196 ALPVQVALAHPHLSGGGFDLPLVGPVFNEYVAAHGLSDRLQFYPGDFFKDPCPSADVLIM 255
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G ILHDW L +K +L++K + AL G+ +V + +IDD RR N GL+MSLNMLIE
Sbjct 256 GHILHDWPLPQKLELLSKCHAALPPGGSLVVYDAIIDDDRRSNAFGLLMSLNMLIETPGG 315
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ A R W + GF V LAG S V K
Sbjct 316 FDYTGAQCREWMRQTGFAEIRVEHLAGPDSMVVGVK 351
>gi|323529544|ref|YP_004231696.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1001]
gi|323386546|gb|ADX58636.1| O-methyltransferase family 2 [Burkholderia sp. CCGE1001]
Length=353
Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust.
Identities = 155/333 (47%), Positives = 201/333 (61%), Gaps = 5/333 (1%)
Query 7 RIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDL 66
R++ +G + SK LL+AV LG+FT+L A A+ + LGL R A+DFLDALV+L L
Sbjct 24 RLLQLGMAFWASKTLLSAVELGVFTQLASGPREAAALTESLGLHPRSALDFLDALVALSL 83
Query 67 LARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSE 126
L R DG Y NTP+ FLD+A+P+Y GGLL++ N R Y FW LTEAL+TG Q+E
Sbjct 84 LERR-DG---AYSNTPDADLFLDKAKPSYVGGLLEMANARLYPFWGSLTEALQTGLPQNE 139
Query 127 VKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLS 186
K TG F+A+Y D L F+ AM S +A+RFP+ Y+ D+G A G L
Sbjct 140 AK-TGGNLFDAIYRDEASLRGFLRAMSGVSLGAARAIAQRFPWSEYKTFIDIGAAQGALP 198
Query 187 RIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQI 246
VA AHPHL FDLP V + + A GL ER++ GDF DP P+ADV+ MG I
Sbjct 199 VQVALAHPHLSGGGFDLPLVGPVFDEYVAAHGLTERLKFYPGDFFKDPCPSADVLIMGHI 258
Query 247 LHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDY 306
LHDW L +K +L++K + AL G+ +V + +IDD RR N GL+MSLNMLIE FDY
Sbjct 259 LHDWPLPQKLELLSKCHAALPPGGSLVVYDAIIDDERRSNAFGLLMSLNMLIETPGGFDY 318
Query 307 SAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
+ A R W +AGF + PL G S V K
Sbjct 319 TGAQCREWMKQAGFADVRIEPLVGPDSMVVGIK 351
>gi|186473411|ref|YP_001860753.1| O-methyltransferase family protein [Burkholderia phymatum STM815]
gi|184195743|gb|ACC73707.1| O-methyltransferase family 2 [Burkholderia phymatum STM815]
Length=353
Score = 278 bits (712), Expect = 8e-73, Method: Compositional matrix adjust.
Identities = 153/338 (46%), Positives = 204/338 (61%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
E SP+ I+ + G+ SK LL+AV L +F L +A+ + LGL R A+DFLDAL
Sbjct 21 EPSPEYILQVAMGFWASKTLLSAVELQVFAHLARGPQSAQPLIAALGLHPRSALDFLDAL 80
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L++L R DG Y NT + FLD ARP+Y GGLL++ N R Y FW LTEAL+TG
Sbjct 81 VALNVLNR-ADGV---YSNTRDADLFLDPARPSYVGGLLEMANSRLYPFWGSLTEALRTG 136
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
Q+E + G FEALY+D RL F+ AM S +A++FP++ +R D+G A
Sbjct 137 APQNESRHGGN-VFEALYSDETRLRTFLRAMSGVSLGAARAIAQQFPWQNHRTFVDLGAA 195
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L +A AHPHL FDLPAV + + ++GL +R++ AG+F DP P+ADV+
Sbjct 196 QGALPVQIALAHPHLSGGGFDLPAVRPVFEEYVASQGLQDRLRFYAGNFFDDPCPSADVL 255
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
MG ILHDW+LD+K+ L+ K ++AL G IV + +IDD RR N GL+MSLNMLIE
Sbjct 256 VMGHILHDWDLDQKRMLLRKCHDALPPGGCLIVYDAMIDDERRHNAFGLLMSLNMLIETP 315
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ W EAGF V L G S A+ K
Sbjct 316 GGFDYTGGQCIEWMREAGFTQVRVERLVGPDSMAIGIK 353
>gi|302548369|ref|ZP_07300711.1| tetracenomycin polyketide synthesis 8-O-methyltransferase [Streptomyces
hygroscopicus ATCC 53653]
gi|302465987|gb|EFL29080.1| tetracenomycin polyketide synthesis 8-O-methyltransferase [Streptomyces
himastatinicus ATCC 53653]
Length=354
Score = 277 bits (708), Expect = 2e-72, Method: Compositional matrix adjust.
Identities = 159/338 (48%), Positives = 202/338 (60%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
E+SP+ I+ +G GY SK LLTAV L +FT L +A LGL R A DFLDAL
Sbjct 16 EISPEPILQVGLGYMASKTLLTAVELDVFTRLAQGPCERGDLAGALGLHSRGAADFLDAL 75
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L L R G + YRN+P FLD + TY GG+L++ N R Y FW LTEAL+TG
Sbjct 76 VALGFLERRG----TEYRNSPSADAFLDREKDTYVGGVLEMANSRLYPFWGSLTEALRTG 131
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
K Q+E K G ++A+Y D LE F+ M S +A++FP+ YR + DVG A
Sbjct 132 KPQNEQKHGG-DVYDAIYHDQAGLERFLNGMTGLSMGMARAIAEKFPWVDYRTVLDVGGA 190
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G + VA H H+ F+LP V + + +T+ GL +R+ GDF AD LP ADVI
Sbjct 191 LGCVPVAVAQRHLHISGGVFELPRVRPVFDKYVTSFGLTDRIAFHGGDFFADDLPTADVI 250
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
+GQILH W LD K+ L+ KAY+AL GA +V + +IDD RR NT GL+ SLNMLIE
Sbjct 251 VLGQILHGWGLDEKRLLLKKAYDALPDGGAVLVYDAIIDDERRHNTFGLLASLNMLIESA 310
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
F+Y+AAD R W EAGF S V PL GG S V K
Sbjct 311 AGFEYTAADGRSWMAEAGFGSTWVEPLMGGYSLLVGIK 348
>gi|162449489|ref|YP_001611856.1| methyltransferase [Sorangium cellulosum 'So ce 56']
gi|161160071|emb|CAN91376.1| putative Methyltransferase [Sorangium cellulosum 'So ce 56']
Length=336
Score = 250 bits (639), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 139/338 (42%), Positives = 190/338 (57%), Gaps = 5/338 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
E+ + I+ +G Y SK LL+AV LG+FT L E + + + +R+G+ R A DF DAL
Sbjct 4 EIDHNAIVRLGMAYAESKTLLSAVELGVFTALAREPLDWQTLRERIGIHPRAARDFFDAL 63
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
V+L LL R+ DG Y NT E +LD+ + +Y GG+L++ N R Y W L+EAL+TG
Sbjct 64 VALRLLRRE-DG---RYSNTREADLYLDKTKKSYIGGMLEMSNARLYGIWGSLSEALRTG 119
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
Q+E+ F L P + F AM S + LA +FP++RY+ DVG A
Sbjct 120 APQNEIGAR-EDIFTWLSKTPEKYREFTQAMTGLSLPSARALAAKFPWDRYKTFADVGTA 178
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241
G L VA AHP + + DLP V + + GL +R++ D DP+P DVI
Sbjct 179 QGGLPVQVALAHPQVTGIGLDLPPVQPVFEDYVREHGLADRLRFQVFDLFKDPIPKVDVI 238
Query 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFG 301
TMG ILH W L K+ + KAY+ALS+ G +V + +IDD RREN G MMSL +L+E
Sbjct 239 TMGHILHGWKLADKRGFIKKAYDALSEGGVLVVYDAMIDDERRENVAGFMMSLTILLETP 298
Query 302 DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
+ FDY++AD GW E GFR L G S V K
Sbjct 299 EGFDYTSADCAGWLREQGFRDVRAEKLIGSDSFVVGVK 336
>gi|330467585|ref|YP_004405328.1| O-methyltransferase family 2 [Verrucosispora maris AB-18-032]
gi|328810556|gb|AEB44728.1| O-methyltransferase family 2 [Verrucosispora maris AB-18-032]
Length=339
Score = 218 bits (556), Expect = 8e-55, Method: Compositional matrix adjust.
Identities = 130/326 (40%), Positives = 178/326 (55%), Gaps = 9/326 (2%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
+S + + +G Y KV LTA LG+FT L D +TAE + RL L R DFLDALV
Sbjct 10 VSAEPLWRLGTAYFSRKVTLTAAELGVFTVLADGPLTAEQLRIRLELHPRGVPDFLDALV 69
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
+LD+L RDGD YRNTP + HFL+E RP+Y G L + R W L +AL+TG+
Sbjct 70 ALDMLERDGD----QYRNTPLSDHFLNEKRPSYVGAFLSAADAR----WDRLADALRTGE 121
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
Q+ G F Y F A MD + +A+ F + + DVG A
Sbjct 122 PQNRWG-AGPQMFTEQYRTTAAWRNFTAGMDYLNGMIGPPVAEAFDWTSVDSVVDVGGAR 180
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L + HPHL+ FDLP V + +T G+ +RV AGDF P+PAADV+
Sbjct 181 GNLVAALLRRHPHLKAGVFDLPGVEPVFIEHMTQLGIADRVTFHAGDFFTVPMPAADVLI 240
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
+ +LHDW L +Q LV++A++AL+ G +VI+ +IDD RR L+ SLNML+
Sbjct 241 LSHVLHDWALQERQALVSRAFDALAPGGRLMVIDPMIDDDRRGTAGALLTSLNMLMVTPH 300
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPL 328
+Y+AA+ R W EAGF +P+
Sbjct 301 GAEYTAAEARDWLTEAGFTGITAVPI 326
>gi|283484099|gb|ADB23385.1| O-methyltransferase [Micromonospora echinospora subsp. challisensis]
Length=334
Score = 217 bits (552), Expect = 3e-54, Method: Compositional matrix adjust.
Identities = 129/332 (39%), Positives = 179/332 (54%), Gaps = 9/332 (2%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLL 67
I+ + GY +K L+AV LGLF L + T I + LGL R DFLD+LV+L +L
Sbjct 10 ILDLAAGYWSAKTFLSAVELGLFGVLAEGGKTEPEIRETLGLHPRATRDFLDSLVALKVL 69
Query 68 ARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEV 127
RD +G Y + A+ LD P+Y GG L++ + Y W LT+ LKTG Q+
Sbjct 70 DRDAEG---RYAISAAAANQLDPKHPSYQGGFLRM-HAWQYGVWGKLTDLLKTGDMQAHT 125
Query 128 KQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSR 187
+ F Y+ P + FM+AMD A+ LA++F + DVG A G ++
Sbjct 126 DRD----FNKFYSRPESVRNFMSAMDGANSAVGPALAEKFDWTEVGSFVDVGGARGNIAA 181
Query 188 IVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQIL 247
++A AHP L +FDLP V + G+ +RV AGDF D LP ADV+ G +L
Sbjct 182 VIAKAHPQLDAGTFDLPPVKPFFDEHMDRLGMTDRVTFHAGDFFNDSLPTADVLIFGHVL 241
Query 248 HDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYS 307
HDWN +++ L+ KAYEAL G +V + LIDD RRE L++SLNM + +Y+
Sbjct 242 HDWNDEQRIALLRKAYEALPVGGRVMVYDALIDDDRRE-PANLLLSLNMQLVTPGGGEYT 300
Query 308 AADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
AD +GW EAGF V+PL SA + K
Sbjct 301 GADCQGWMREAGFTETSVLPLTDADSAVIGRK 332
>gi|161367427|gb|ABX71152.1| Lcz35 [Streptomyces sanglieri]
Length=323
Score = 215 bits (547), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 130/331 (40%), Positives = 175/331 (53%), Gaps = 9/331 (2%)
Query 9 MAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLA 68
M I G+ ++ L +AV L LFT L T E + D LGL PA DFLDALV+L LL
Sbjct 1 MDIASGFWRARALFSAVDLDLFTHLAKGPATREELQDSLGLHPSPAEDFLDALVALGLLQ 60
Query 69 RDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVK 128
R+ DG Y N +LD A+ +Y GG + Y W LT L++G +
Sbjct 61 RE-DG---RYANARAAERYLDRAKDSYVGGFFTFMSYSLYPAWGRLTGLLRSGG-----R 111
Query 129 QTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRI 188
Q G F Y D ++ FM AMD+ S E L +RF + YR D+G A G L+
Sbjct 112 QEGLDDFGEWYKDLDQVRGFMHAMDSVSAPVTEELVRRFDWSAYRTFADLGGARGNLAGH 171
Query 189 VAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQILH 248
+ AH HL+ +FD+PAV + + G+ ++V GDF DPLP DV+ G +LH
Sbjct 172 LVKAHTHLRGTTFDVPAVKPLFEEHVAKLGVADKVDFQGGDFRIDPLPETDVLIFGHVLH 231
Query 249 DWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSA 308
DW+ D ++ LV +AY+AL GA ++ E L+DD RR L+MSLNM + D +Y+A
Sbjct 232 DWDADTRELLVKRAYDALRPGGALLIYEELLDDDRRGPARSLLMSLNMRLVRSDGSEYTA 291
Query 309 ADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
A+ RGW EAGF V L VA K
Sbjct 292 AESRGWLREAGFAEVSVEDLTATERLVVARK 322
>gi|134099420|ref|YP_001105081.1| putative 8-O-methyltransferase [Saccharopolyspora erythraea NRRL
2338]
gi|291006191|ref|ZP_06564164.1| putative 8-O-methyltransferase [Saccharopolyspora erythraea NRRL
2338]
gi|133912043|emb|CAM02156.1| putative 8-O-methyltransferase [Saccharopolyspora erythraea NRRL
2338]
Length=335
Score = 213 bits (541), Expect = 5e-53, Method: Compositional matrix adjust.
Identities = 125/336 (38%), Positives = 193/336 (58%), Gaps = 10/336 (2%)
Query 6 DRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLD 65
+ I + G+ ++ + TAV LG+F L +T++ + D+LGL R A DF + LV+L
Sbjct 8 NHIQELALGFMSARAVHTAVELGVFPLLAQGPLTSDELCDQLGLHGRGARDFFNCLVALG 67
Query 66 LLARDGDGPGSHYRNTPETAHFL-DEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQ 124
LL DG Y NT T+ +L D PTY GG+L+ Y W L +AL+TG++Q
Sbjct 68 LL-EHADG---RYVNTAATSRYLGDPDAPTYVGGMLEYMGSHWYWSWGRLGDALRTGRSQ 123
Query 125 SEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG- 183
S G+ +EA+++DP E F AM S LA+ FP++ + D+GC+DG
Sbjct 124 S---YGGQVPYEAIHSDPGLSEEFQRAMSGGSVAASTALAESFPWQDVATVADIGCSDGS 180
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
+LSR++ A HPHL + FDLP V + + GL +R++ GDF PAAD +
Sbjct 181 VLSRLLLA-HPHLTGLGFDLPMVEQGFDKTSARHGLADRMRFTPGDFRTASFPAADAVVF 239
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G +L DW+L ++ L+AKAY+AL++ G ++ + L++ +RE+ GL++SL+ML++ G
Sbjct 240 GHLLIDWDLATRRMLLAKAYDALAEGGTILIYDMLVEQDQRESAPGLLISLHMLVDQGGG 299
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
Y+A++ GW +AGFR V PL+G A K
Sbjct 300 VSYTASECFGWLADAGFRQCRVRPLSGADQLITAVK 335
>gi|197116283|dbj|BAG68852.1| O-methyltransferase, family 2 [Streptomyces albulus]
Length=283
Score = 210 bits (535), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 123/289 (43%), Positives = 162/289 (57%), Gaps = 9/289 (3%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
SP + + + +K +L+AV +G+FTEL E + + DRLGL RPA DF DALV+
Sbjct 3 SPQPVTDLMWAHWKTKTMLSAVEVGVFTELAKEPLPGPVLRDRLGLHPRPATDFFDALVA 62
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARP-TYAGGLLKIWNERNYRFWADLTEALKTGK 122
L LL R D Y N PE A +LD RP +Y GG + DLTE L+TG+
Sbjct 63 LGLLVRSDD----RYANAPEAAEYLDRHRPASYLGGSFLT---QCAGLADDLTEVLRTGR 115
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
A + + GR F+ A+YA + AF M A S +A++FP+ERYR L D+GCA+
Sbjct 116 AARQARD-GRDFYRAMYAASDSVRAFQKDMTALSMGPARAIAEKFPWERYRSLADIGCAE 174
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L V A HPHL V FDLP G+ +RV GDF DPLP+ADV+
Sbjct 175 GALPGHVLARHPHLTAVGFDLPPARAGFAEYTERLGVADRVTFQEGDFFHDPLPSADVLV 234
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLM 291
G +LH+W + K +L+ A+ AL GA +V ETLIDD RR N GL+
Sbjct 235 FGHVLHNWGQEEKLRLLRAAHRALPDGGAVLVYETLIDDERRSNAIGLI 283
>gi|254389419|ref|ZP_05004646.1| O-methyltransferase [Streptomyces clavuligerus ATCC 27064]
gi|294815796|ref|ZP_06774439.1| O-methyltransferase family protein [Streptomyces clavuligerus
ATCC 27064]
gi|197703133|gb|EDY48945.1| O-methyltransferase [Streptomyces clavuligerus ATCC 27064]
gi|294328395|gb|EFG10038.1| O-methyltransferase family protein [Streptomyces clavuligerus
ATCC 27064]
Length=350
Score = 207 bits (527), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 133/337 (40%), Positives = 186/337 (56%), Gaps = 7/337 (2%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
+SP + + + ++VLL+A+ LG+F L +TA+A+ RLG+ RPA DF DALV
Sbjct 21 ISPRPVTDLIWAHWRTRVLLSAIDLGVFAALSAGPLTADALRARLGVHPRPAADFFDALV 80
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
+L LL R D HY N P +A +LD A P G + + +LT L+TG+
Sbjct 81 ALGLLERHAD----HYANAPASAEYLDPALPHTCIG--PSLSAQCPGMADELTRLLRTGE 134
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
A + GR F+ A+ AD R + AF M A S + +A++FP+ YR L D+GCA+
Sbjct 135 ALRRARD-GRDFYAAVCADDRSVRAFQRDMTALSIGSARAIAEKFPWAGYRTLADIGCAE 193
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L + AHPHL FDLPA + GL +RV AGDF D LPAADV+
Sbjct 194 GALPAQILLAHPHLSATGFDLPAARTGFEQYTARLGLADRVTFTAGDFFHDDLPAADVLV 253
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
G +LH+W + + +L+ +A+ AL + GA ++ ETLIDD RR+N GL++SL M +E
Sbjct 254 FGHVLHNWPPEDRLRLLRRAHRALPEGGAVLIYETLIDDERRDNAIGLLLSLVMQLEVPG 313
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
DY+ A+ W AGF L G S VA K
Sbjct 314 GSDYTGAECHRWLTAAGFTDPRTEHLDGPESMVVAVK 350
>gi|326444140|ref|ZP_08218874.1| O-methyltransferase family 2 [Streptomyces clavuligerus ATCC
27064]
Length=331
Score = 207 bits (526), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 133/337 (40%), Positives = 186/337 (56%), Gaps = 7/337 (2%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
+SP + + + ++VLL+A+ LG+F L +TA+A+ RLG+ RPA DF DALV
Sbjct 2 ISPRPVTDLIWAHWRTRVLLSAIDLGVFAALSAGPLTADALRARLGVHPRPAADFFDALV 61
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
+L LL R D HY N P +A +LD A P G + + +LT L+TG+
Sbjct 62 ALGLLERHAD----HYANAPASAEYLDPALPHTCIG--PSLSAQCPGMADELTRLLRTGE 115
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
A + GR F+ A+ AD R + AF M A S + +A++FP+ YR L D+GCA+
Sbjct 116 ALRRARD-GRDFYAAVCADDRSVRAFQRDMTALSIGSARAIAEKFPWAGYRTLADIGCAE 174
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L + AHPHL FDLPA + GL +RV AGDF D LPAADV+
Sbjct 175 GALPAQILLAHPHLSATGFDLPAARTGFEQYTARLGLADRVTFTAGDFFHDDLPAADVLV 234
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
G +LH+W + + +L+ +A+ AL + GA ++ ETLIDD RR+N GL++SL M +E
Sbjct 235 FGHVLHNWPPEDRLRLLRRAHRALPEGGAVLIYETLIDDERRDNAIGLLLSLVMQLEVPG 294
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
DY+ A+ W AGF L G S VA K
Sbjct 295 GSDYTGAECHRWLTAAGFTDPRTEHLDGPESMVVAVK 331
>gi|117956311|gb|ABK58689.1| PdmT [Actinomadura hibisca]
Length=339
Score = 204 bits (520), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 128/336 (39%), Positives = 179/336 (54%), Gaps = 14/336 (4%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLL 67
++ +G Y SKVLL+AV LGLFT L T + LGL R A DFLDALVSL LL
Sbjct 13 VLRMGIAYFRSKVLLSAVELGLFTRLAKGPATGPQLRGELGLHPRAARDFLDALVSLGLL 72
Query 68 ARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG----KA 123
R+ Y NT +LD A+PTY GG L + + + + W DLT L+ G
Sbjct 73 RREN----GVYDNTAVADTYLDAAKPTYTGGFLTMLDHQ-FAQWGDLTRLLREGGRAYPV 127
Query 124 QSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADG 183
E+ Q + ++ADP RL FM+AMD ++ + LA + + + D+G A G
Sbjct 128 DDELDQ-----HDEMHADPARLRRFMSAMDGINQFSGAALADAYDWSAHASFVDLGGARG 182
Query 184 LLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITM 243
L+ + AHPHL DLPAV + + + GL +V GDF DPLPAA+V+
Sbjct 183 NLAAELRKAHPHLAAGVMDLPAVQTVFDEHMESLGLTGQVAFTGGDFFNDPLPAAEVLIF 242
Query 244 GQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDA 303
G +LHDW+ + + LV +AYEAL G +V + +IDD RR + L+ SL+M++
Sbjct 243 GHVLHDWSPELRAALVRRAYEALPSGGELLVYDVMIDDERRTHDFSLLTSLHMMLVSPGG 302
Query 304 FDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
+Y+A D R W AGF +PL + +A K
Sbjct 303 GEYTARDCREWMTAAGFGVTRTVPLTDIDTLVIARK 338
>gi|196232088|ref|ZP_03130943.1| O-methyltransferase family 2 [Chthoniobacter flavus Ellin428]
gi|196223810|gb|EDY18325.1| O-methyltransferase family 2 [Chthoniobacter flavus Ellin428]
Length=250
Score = 203 bits (516), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 114/229 (50%), Positives = 137/229 (60%), Gaps = 0/229 (0%)
Query 3 LSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALV 62
L P I+ G+ SKVLLTAV GLFT+LG +T E + L L R DF DALV
Sbjct 5 LDPSSILQTAFGFWHSKVLLTAVEFGLFTKLGSRRLTGEELGAELQLHPRAIADFFDALV 64
Query 63 SLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGK 122
++ L RDGDG Y NTPE A FLDE P Y GG+L + N R ++FW DL EAL+TG+
Sbjct 65 AMKFLGRDGDGAPGKYFNTPEGALFLDETSPRYIGGILIMLNARLFKFWNDLPEALRTGR 124
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
Q+EVK + FE LYAD +LE FM AM SR N E A++F F + + LCDVG A
Sbjct 125 PQNEVKHGQKGIFEELYADLPKLEQFMGAMTGLSRLNFEAFAEKFDFSKSQTLCDVGGAT 184
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFL 231
GLL VA H HLQCVSFDL + R + A GL RV+ A FL
Sbjct 185 GLLCTEVAKRHSHLQCVSFDLRRSRRLRRSIIPAAGLKGRVRTAARRFL 233
>gi|302540363|ref|ZP_07292705.1| tetracenomycin polyketide synthesis 8-O-methyltransferase [Streptomyces
hygroscopicus ATCC 53653]
gi|302457981|gb|EFL21074.1| tetracenomycin polyketide synthesis 8-O-methyltransferase [Streptomyces
himastatinicus ATCC 53653]
Length=331
Score = 201 bits (511), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 135/337 (41%), Positives = 183/337 (55%), Gaps = 9/337 (2%)
Query 4 SPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVS 63
SP + + Y +K +L+A+ LG+FTEL E + + +A RLGL DFLDALV+
Sbjct 3 SPQPVTELFWAYWKTKTMLSAIELGVFTELAKEPLRGDELAGRLGLGPGAVGDFLDALVA 62
Query 64 LDLLARDGDGPGSHYRNTPETAHFLDEARP-TYAGGLLKIWNERNYRFWADLTEALKTGK 122
LDLL R GD Y NTP +LD +P TY G + + DLT L+TG+
Sbjct 63 LDLLDRTGD----VYANTPAADEYLDAGKPATYLG---DSYLTQCAGLADDLTGVLRTGE 115
Query 123 AQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCAD 182
A + TGR F+ YA + AF M A S + ++A FP++ YR L D+G ++
Sbjct 116 ALRGAR-TGRDFYADTYATSNSVRAFQRDMTALSIGSARVIADSFPWDDYRSLADIGTSE 174
Query 183 GLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT 242
G L + HPHL V FDLP E A L +R+ GDF D LP+ADV+
Sbjct 175 GALPGRILLRHPHLTAVGFDLPQAREGFEEYTGALDLADRMSFQPGDFFRDELPSADVLV 234
Query 243 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGD 302
G ILH+W L+ K+ L+ KAY AL + GA ++ ETLID RR N GL++SL M +E
Sbjct 235 FGHILHNWGLEEKRLLLDKAYRALPEGGAVLIYETLIDGDRRSNAVGLILSLMMHLEVPG 294
Query 303 AFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
FDY+ + + W EAGFR V L G S + +K
Sbjct 295 GFDYTGPECQEWLREAGFRETRVEHLDGPESMIIGFK 331
>gi|73621289|gb|AAZ78343.1| OxyT [Streptomyces rimosus]
Length=344
Score = 197 bits (501), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 120/314 (39%), Positives = 167/314 (54%), Gaps = 5/314 (1%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLL 67
++ + Y +K L +AV LGLF L D TAE + DRL ++ A +FLDALV+L+LL
Sbjct 15 LLQLTTAYHQAKALHSAVELGLFDLLADGPATAEEVKDRLRIVHPLAKEFLDALVALELL 74
Query 68 ARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEV 127
DGD YRN+P FL Y GG + ++Y WA LT AL+ G+A S
Sbjct 75 EADGD----RYRNSPAAQAFLVSGASEYLGGTVLQHARKHYHVWAGLTTALQEGEAGSGA 130
Query 128 KQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSR 187
+ G + Y DP R MA D S E LA+R + Y D+G A G L+
Sbjct 131 EAHGPEAYPKHYEDPERARQVMAHFDTFSSFTAEELARRVDWSGYGSFIDIGGARGNLAT 190
Query 188 IVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQIL 247
VA AHPHL FDLPA+ +A + GL RV+ GDFL DPLP+AD + G +L
Sbjct 191 RVALAHPHLHGAVFDLPALAPLAGELIRERGLEGRVRFHGGDFLTDPLPSADAVVTGHVL 250
Query 248 HDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYS 307
DW + ++++L+A+ +EAL GA +V + + D A ++ LN + GD+ S
Sbjct 251 PDWPVPQRRKLLARIHEALPSGGALVVYDLMTDPA-TTTVHDVLQRLNHGLIRGDSSSSS 309
Query 308 AADFRGWCGEAGFR 321
++R EAGFR
Sbjct 310 VEEYRAEIEEAGFR 323
>gi|730914|sp|P39896.1|TCMO_STRGA RecName: Full=Tetracenomycin polyketide synthesis 8-O-methyl
transferase tcmO
gi|153500|gb|AAA67519.1| O-methyltransferase [Streptomyces glaucescens]
Length=339
Score = 197 bits (501), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 120/335 (36%), Positives = 181/335 (55%), Gaps = 7/335 (2%)
Query 5 PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSL 64
P I+ + + S+ L++AV L LFT L + + + +R G+ R A DFLDALV+L
Sbjct 10 PGDILQLTMAFYGSRALISAVELDLFTLLAGKPLPLGELCERAGIHPRGARDFLDALVAL 69
Query 65 DLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQ 124
LL R+G+ YRN+P LD +P Y GG ++ + + + WA LTEAL+TG+ Q
Sbjct 70 GLLEREGE---DTYRNSPAADRHLDRRKPGYVGGYARLADTKLFPVWARLTEALRTGEKQ 126
Query 125 SEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGL 184
Q G FF YADP F+ AMDA + LA + Y D+G A G
Sbjct 127 VP-SQGG--FFGG-YADPEAARGFLGAMDAVNGGVGHSLAGALDWTEYSSFVDLGGARGN 182
Query 185 LSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMG 244
L+ + AHPHL+ FDLP + + + + ++V+ GDF DPLP ADV +G
Sbjct 183 LAAHLHRAHPHLRATCFDLPEMEPFFQEHMKSLETTDQVRFAGGDFFTDPLPRADVFIVG 242
Query 245 QILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAF 304
ILH + L +++ L+A+ ++AL+ GA +V + +IDD RR L+ SLNML+ +
Sbjct 243 HILHYFGLRQREALIARIHQALTPGGAVLVYDRMIDDDRRSAALSLLGSLNMLLTSDEGR 302
Query 305 DYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
+Y+ A+ W +AGF ++G + A+ K
Sbjct 303 EYTPAECVRWLSDAGFTDVRTTAVSGPDTLAIGRK 337
>gi|161367392|gb|ABX71118.1| Lct35 [Streptomyces rishiriensis]
Length=322
Score = 193 bits (490), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 125/331 (38%), Positives = 169/331 (52%), Gaps = 10/331 (3%)
Query 9 MAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLA 68
M I G+ ++ L +AV LGLFT L + T E I LGL A DFLDALVSL LL
Sbjct 1 MDIASGFWRARALFSAVELGLFTHLAEGPATQEEIERSLGLHPSAAADFLDALVSLGLLD 60
Query 69 RDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVK 128
R+ DG Y N+ A +LD + Y GG + Y W LT L++G +
Sbjct 61 RE-DG---RYANSAAAARYLDRTKDAYVGGFFTFMSYALYPAWGRLTGLLRSGS-----R 111
Query 129 QTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRI 188
Q G+ F Y D ++ FM AMD+ S E LA+RF + Y D+G A G L+
Sbjct 112 QEGQDDFGDWYKDLDQVRGFMDAMDSVSAPVTEELARRFDWSAYSTFADLGGARGNLTGH 171
Query 189 VAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQILH 248
+ AHPHL+ +FD+PA+ + G+ ++V GDF DPLP ADV+ G +LH
Sbjct 172 LVRAHPHLRGTTFDVPAIKPLFEEHAARLGVADKVAFQGGDFRTDPLPEADVLIFGHVLH 231
Query 249 DWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSA 308
DW+ + LV +A + GA ++ E L+DD RR L+MSLNM + +Y+A
Sbjct 232 DWDDATRALLVGRATTPCAG-GALLIYEELLDDDRRGPARSLLMSLNMRLVRSGGSEYTA 290
Query 309 ADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
A+ R W AGF V L VA K
Sbjct 291 AESRVWLEAAGFTDITVEELTATERLIVARK 321
>gi|154623247|emb|CAM34375.1| putative O-methyltransferase [Streptomyces tendae]
Length=338
Score = 186 bits (472), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 115/321 (36%), Positives = 169/321 (53%), Gaps = 9/321 (2%)
Query 19 KVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHY 78
+ +L AV L LFT L D T I +R L +R DFLDALVS+ LL R+ DG Y
Sbjct 25 RTVLFAVELDLFTALADSPATEPEIRERFSLGERGTRDFLDALVSVGLLVRE-DGV---Y 80
Query 79 RNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEAL 138
R P A +LD R + G L + R W + + L++G+ Q+ G F
Sbjct 81 RAAPLAAGYLDSRRSAFLGRFLGQADAR----WGRVAQGLRSGEPQNGAG-GGAGMFTRQ 135
Query 139 YADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQC 198
+ D + A+ MDA + + L F + R +R+ DVG A G + + AHPHLQ
Sbjct 136 HRDQQAWRAYYGGMDALNGPSGAALVGAFDWSRVKRVTDVGGARGNVLAHLVRAHPHLQA 195
Query 199 VSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQILHDWNLDRKQQL 258
FDLP V + + GL R+ C G+F DPLP +DV+ G +LHDW++ +++ L
Sbjct 196 TVFDLPPVEAVFSEHMRELGLTGRIAFCPGNFFEDPLPESDVVVFGHVLHDWDVSQRRVL 255
Query 259 VAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAADFRGWCGEA 318
KAYEA++ G +V +T+ID+ RRE T L++S+NM++ +Y+ ++ W EA
Sbjct 256 ARKAYEAVAPGGCALVYDTMIDEERRERTNSLLVSINMMLCTPGGGEYTPSEGGRWFAEA 315
Query 319 GFRSFEVIPLAGGSSAAVAYK 339
GF E L G + +A K
Sbjct 316 GFAHVEHRHLHGDDTLLIARK 336
>gi|292659126|gb|ADE34508.1| SsfM1 [Streptomyces sp. SF2575]
Length=332
Score = 182 bits (462), Expect = 7e-44, Method: Compositional matrix adjust.
Identities = 119/334 (36%), Positives = 173/334 (52%), Gaps = 11/334 (3%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLL 67
I + GY +++L +AV +GLF L D ++A I RL L R DFL+ALV+L LL
Sbjct 7 ISRLNTGYAEARILHSAVEVGLFELLSDGPLSAAEIVSRLELHPRLVGDFLNALVALGLL 66
Query 68 ARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEV 127
RDG Y N+ + L P + GG +K +R+Y W LTEAL+ G+ ++ +
Sbjct 67 TRDG----RQYANSTVSQEVLVPGGPVFLGGRVKATAQRHYHTWGKLTEALRDGEPKAAM 122
Query 128 KQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSR 187
G E LY+DP AF A MDA + LA + Y+ D G A G ++
Sbjct 123 ---GLGAMERLYSDPALARAFFAHMDANNAVVALQLATVVDWSSYKSFVDAGGARGNVAA 179
Query 188 IVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQIL 247
+ AHPHL+ DL + + G V GDF D LPAADVI G +L
Sbjct 180 TLVKAHPHLRGSVMDLGKAEPLFDELMAERGTTGSVVFHPGDFFTDDLPAADVIVYGHVL 239
Query 248 HDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYS 307
HDW+ ++ Q LV +AY+AL GA +V + ++D+ + L+ SLN+ + +Y+
Sbjct 240 HDWSAEQCQVLVERAYQALPSGGALVVYDQMLDE-ESPDLRSLVGSLNVALLSEGGSEYT 298
Query 308 AADFRGWCGEAGFR--SFEVIPLAGGSSAAVAYK 339
A+FR W +AGFR E +P G + A+A+K
Sbjct 299 VAEFRAWAEKAGFRFDRAERLP-RGNDTVAIAHK 331
>gi|40644841|emb|CAE17534.1| O-methyltransferase [Streptomyces griseus subsp. griseus]
Length=357
Score = 180 bits (456), Expect = 4e-43, Method: Compositional matrix adjust.
Identities = 117/321 (37%), Positives = 164/321 (52%), Gaps = 12/321 (3%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDLL 67
++ + Y SKVL +AV LGLF L +E TAE + RLG+ RP DFLDALV L LL
Sbjct 20 LLRLNTAYFQSKVLQSAVELGLFALLAEEPATAETVFGRLGVRARPGADFLDALVGLGLL 79
Query 68 ARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEV 127
R DG HY N PE A FL P Y GG + R+YR WA LT+ L+ A
Sbjct 80 ERK-DG---HYSNKPEAAAFLVPDAPGYLGGSIAQHARRHYRSWASLTDLLRNEPAADSP 135
Query 128 KQT--GRPF-----FEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGC 180
T G P F + + + M MDA + L + + R+R DVG
Sbjct 136 PATAGGDPAKVQLDFHKDFENLDNVRRLMGHMDAFNTFVAHELGRCVDWSRHRTFLDVGG 195
Query 181 ADGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADV 240
A G ++ + H HL+ FDLPAV + + A G +V AGDF DPLP +DV
Sbjct 196 ARGNVAARLVRTHGHLRGGVFDLPAVRPLFDEHMAALGTASQVGFTAGDFFDDPLPESDV 255
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
+ +G +LHDW +++L+ + + A+ G +V + ++ D R++ L+ SLN I
Sbjct 256 VILGHVLHDWPPAARERLLERVFAAVRPGGRVVVYDAMLTD-ERDDAVALLQSLNCSIMR 314
Query 301 GDAFDYSAADFRGWCGEAGFR 321
+Y+ A+ RG+ AGFR
Sbjct 315 DGGSEYTVAECRGYVEHAGFR 335
>gi|229014702|ref|ZP_04171812.1| O-methyltransferase, family 2 [Bacillus mycoides DSM 2048]
gi|228746608|gb|EEL96501.1| O-methyltransferase, family 2 [Bacillus mycoides DSM 2048]
Length=350
Score = 175 bits (444), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 100/326 (31%), Positives = 165/326 (51%), Gaps = 6/326 (1%)
Query 2 ELSPDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDAL 61
++S + ++ I G+ SK L +AV L +F + + + + + L + RPA L A
Sbjct 14 DISANNLLNIATGFWASKALASAVELEIFNIMPKQGINIKEVTKELEIQMRPAEMLLTAC 73
Query 62 VSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTG 121
+L LL + G+ Y N+P + FL + P Y GG++ + ++R Y W+ LTEA+KT
Sbjct 74 TALGLLTKKGE----LYYNSPLSNKFLVKGEPYYFGGVITMLDKREYIPWSKLTEAIKTD 129
Query 122 KAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCA 181
+ Q +K FE++ +P F M + S + + L K F F + +L DVG
Sbjct 130 QMQV-LKDDSLGIFESISVNPEEQRIFTEGMHSWSIQTGKELTKVFDFSQNTQLLDVGGC 188
Query 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLP-AADV 240
G +P L V FDL +IA+ K+ L R++ GDF + LP +DV
Sbjct 189 SGAYCIEAVQKYPDLHAVVFDLAPALKIAKEKIEQAELSHRIKTHTGDFFKEELPKGSDV 248
Query 241 ITMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEF 300
I + +L +W+ + +++ K Y L + G+ I+ E +IDD + + +MSLNMLIE
Sbjct 249 ILLSMLLQNWSPEENHEILQKCYNVLPEGGSIIISELMIDDDKTGPISAALMSLNMLIET 308
Query 301 GDAFDYSAADFRGWCGEAGFRSFEVI 326
+YS +++ GW GF + I
Sbjct 309 IKGRNYSWSEYEGWLKNIGFIDIQRI 334
>gi|302843296|ref|XP_002953190.1| hypothetical protein VOLCADRAFT_121144 [Volvox carteri f. nagariensis]
gi|300261577|gb|EFJ45789.1| hypothetical protein VOLCADRAFT_121144 [Volvox carteri f. nagariensis]
Length=435
Score = 173 bits (439), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 124/360 (35%), Positives = 175/360 (49%), Gaps = 74/360 (20%)
Query 17 PSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAI----DFLDALVSLDLLARDGD 72
PS + + AVG L + +++ LGL + P DFLD LVS+ L R
Sbjct 113 PSHLPVFAVGASL-----------QQLSEMLGLCREPHFRGGADFLDLLVSVACLER--- 158
Query 73 GPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGR 132
+GG+L++ +ER++ ++ L AL+ G+ + Q
Sbjct 159 -----------------------SGGILRLNSERSFPMFSHLVHALQHGEMPPDAFQRIT 195
Query 133 PFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAA 192
+D E F M AS N +LLA+RFPF R+ + D+G + G L+ VA+
Sbjct 196 DIHTTFNSDVAAAEFFAEGMTGASLGNFQLLAERFPFSRFTSVGDLGGSAGCLACCVASR 255
Query 193 HPHLQCVSFDLPAVTEIARRKL---TAEG-----------------------LGERVQAC 226
H HL ++DLP V A R + T G L RVQ
Sbjct 256 HAHLTATTYDLPPVHAAAERYVRGFTLRGQAAAGGGGGGDGGAGAGDGDGLDLQRRVQVR 315
Query 227 AGDFLA-DPLPAA-DVITMGQILHDWNLDRKQQLV---AKAYEALSKEGAFIVIETLIDD 281
DF + DP+PA DV+T G +LHDW +D+K L+ ++A+E+L GA I I+ LIDD
Sbjct 316 DYDFFSPDPIPAGHDVLTYGMVLHDWGIDKKLLLMRKASRAFESLPPGGALIAIDHLIDD 375
Query 282 ARRENTTGLMMSLNMLIEFG--DAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
R + L MSL ML+EFG +AFDYS +F W + GF S E+IPL G + AAVAYK
Sbjct 376 NRTNSAVQLGMSLTMLLEFGRENAFDYSFKEFSEWATQVGFSSLELIPLLGTAKAAVAYK 435
>gi|154623239|emb|CAM34367.1| putative O-methyltransferase [Streptomyces tendae]
Length=333
Score = 173 bits (438), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 119/333 (36%), Positives = 165/333 (50%), Gaps = 12/333 (3%)
Query 7 RIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLDALVSLDL 66
RI + G+ +K+LLTA+ LGLFT L D + E + LGL R DFL ALV+L L
Sbjct 11 RINDLALGFASAKILLTALELGLFTRLADGPCSEERLRTDLGLHGRGMTDFLTALVALGL 70
Query 67 LARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSE 126
L RDGDG YRN P TA +L P YAGG L+ N Y W L+ AL+TG Q+
Sbjct 71 LERDGDG----YRNAPHTARYLVRG-PGYAGGFLEGANLVLYPAWGGLSAALRTGAPQNA 125
Query 127 VKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLS 186
FE + DP R ++A MDA S L ++ + DVG A G L
Sbjct 126 GD------FEEMLGDPGRQRGYLAMMDALSGPLAPDLGTALDWDGRTHVTDVGGARGNLL 179
Query 187 RIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQI 246
++ PHL+ FD P A G R+ GDF D LP DV+ +G +
Sbjct 180 SLLLRDRPHLKGTVFDRPQNAAACAEHTAALGTAGRITFTGGDFFTDDLPECDVMVIGHV 239
Query 247 LHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDY 306
L D++ ++++ LV KA A+ GA +V + + DA R ++ SL+ML+ Y
Sbjct 240 LADFSPEQRRSLVGKAQRAVRPGGALLVYDPM-PDADRPQLLDVIGSLHMLVMSPAGSGY 298
Query 307 SAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK 339
A+ GW EAGFR V + G++ ++
Sbjct 299 RPAECAGWLEEAGFRDVTVRRIGMGNTLVTGHR 331
>gi|291442186|ref|ZP_06581576.1| O-methyltransferase family 2 [Streptomyces ghanaensis ATCC 14672]
gi|291345081|gb|EFE72037.1| O-methyltransferase family 2 [Streptomyces ghanaensis ATCC 14672]
Length=340
Score = 172 bits (437), Expect = 6e-41, Method: Compositional matrix adjust.
Identities = 111/333 (34%), Positives = 168/333 (51%), Gaps = 11/333 (3%)
Query 8 IMAIGGGYGPSKVLLTAVGLGLFTELGDE-AMTAEAIADRLGLLKRPAIDFLDALVSLDL 66
IM + G S+ L+TA +F MT+ +AD +GL +RP + A L L
Sbjct 11 IMNMVSGLWVSQTLVTAHERDVFGHFAKRPGMTSAQLADEMGLEERPVEQLVTACAGLGL 70
Query 67 LARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYRFWADLTEALKTGKAQSE 126
L RDG+G YRNTP T +L Y GG ++I + +Y W L EAL+T + +
Sbjct 71 LERDGEG----YRNTPMTDRYLLRGGEDYVGGWVEIVSRHDYPGWLRLGEALRTNRPTAW 126
Query 127 VKQTGRPFFEALYADPRRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLS 186
+ F+ +P +E+F M A SR LA L DVG G +
Sbjct 127 DSERRDSLFDD--ENPVVVESFWEGMSAISRPTARALADAVDLSGDLSLLDVGGGGGAYA 184
Query 187 RIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPA-ADVITMGQ 245
++ +P L+ FDLP V ++ R+K+ G G R+ AGDF D LP+ DV+ +
Sbjct 185 IELSRVYPSLRATIFDLPFVCDLTRKKVEQAGFGNRISFAAGDFFTDQLPSDQDVVLLSM 244
Query 246 ILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIE-FGDAF 304
ILHDW++D+ + ++ YEAL+ G ++ E L+ D + +MSL+ML+E FG
Sbjct 245 ILHDWDVDQCKSILRSCYEALAPGGRLLISELLVADTKDGPLDATLMSLSMLVETFGR-- 302
Query 305 DYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVA 337
+Y+ A++R W E GF E+ P A ++ V
Sbjct 303 NYTGAEYRDWLLETGFTDVEIRPFAAPAANGVV 335
Lambda K H
0.322 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 614457248732
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40