BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0601c
Length=156
Score E
Sequences producing significant alignments: (Bits) Value
gi|57996832|emb|CAI45378.1| artificial two-component regulatory ... 298 1e-79
gi|15607741|ref|NP_215115.1| two component sensor kinase [Mycoba... 298 2e-79
gi|167969025|ref|ZP_02551302.1| putative two component sensor ki... 298 2e-79
gi|289568535|ref|ZP_06448762.1| two component system sensor kina... 276 1e-72
gi|336177575|ref|YP_004582950.1| integral membrane sensor signal... 95.1 3e-18
gi|158315648|ref|YP_001508156.1| integral membrane sensor signal... 93.6 9e-18
gi|229494403|ref|ZP_04388166.1| sensor kinase, two-component sys... 91.7 3e-17
gi|226304508|ref|YP_002764466.1| two-component histidine kinase ... 90.9 5e-17
gi|229489858|ref|ZP_04383714.1| sensor kinase, two-component sys... 90.1 1e-16
gi|257126115|ref|YP_003164229.1| histidine kinase [Leptotrichia ... 90.1 1e-16
gi|260888930|ref|ZP_05900193.1| sensor histidine kinase [Leptotr... 89.7 1e-16
gi|226349582|ref|YP_002776696.1| two-component histidine kinase ... 89.4 1e-16
gi|344330335|gb|EGW41636.1| HAMP domain protein [Desulfosporosin... 87.8 5e-16
gi|94967341|ref|YP_589389.1| periplasmic sensor signal transduct... 87.4 7e-16
gi|340752079|ref|ZP_08688889.1| sensor histidine kinase [Fusobac... 86.3 1e-15
gi|300786953|ref|YP_003767244.1| two-component system histidine ... 86.3 1e-15
gi|340528444|gb|AEK43649.1| two-component system histidine kinas... 86.3 1e-15
gi|111025332|ref|YP_707752.1| sensor histidine kinase [Rhodococc... 85.9 2e-15
gi|119715850|ref|YP_922815.1| ATPase domain-containing protein [... 85.9 2e-15
gi|302870966|ref|YP_003839602.1| integral membrane sensor signal... 85.5 2e-15
gi|297160787|gb|ADI10499.1| putative two-component system sensor... 85.5 2e-15
gi|297561738|ref|YP_003680712.1| integral membrane sensor signal... 85.1 3e-15
gi|333979456|ref|YP_004517401.1| integral membrane sensor signal... 85.1 3e-15
gi|320008510|gb|ADW03360.1| integral membrane sensor signal tran... 84.7 4e-15
gi|296170766|ref|ZP_06852338.1| sensor histidine kinase [Mycobac... 84.7 4e-15
gi|284041763|ref|YP_003392103.1| integral membrane sensor signal... 84.7 5e-15
gi|342858650|ref|ZP_08715305.1| hypothetical protein MCOL_07231 ... 84.3 5e-15
gi|29826612|ref|NP_821246.1| two-component system sensor kinase ... 84.0 7e-15
gi|222528318|ref|YP_002572200.1| histidine kinase [Caldicellulos... 83.6 8e-15
gi|300790442|ref|YP_003770733.1| two-component system sensor kin... 83.6 9e-15
gi|311897137|dbj|BAJ29545.1| putative two-component system senso... 83.6 9e-15
gi|83590321|ref|YP_430330.1| periplasmic sensor signal transduct... 83.2 1e-14
gi|336402308|ref|ZP_08583046.1| hypothetical protein HMPREF0127_... 83.2 1e-14
gi|298481286|ref|ZP_06999479.1| two-component system response re... 82.8 1e-14
gi|237720753|ref|ZP_04551234.1| two-component system sensor hist... 82.8 1e-14
gi|299145539|ref|ZP_07038607.1| putative two-component regulator... 82.8 1e-14
gi|315918676|ref|ZP_07914916.1| two-component system sensor hist... 82.8 1e-14
gi|336416202|ref|ZP_08596538.1| hypothetical protein HMPREF1017_... 82.8 1e-14
gi|226228543|ref|YP_002762649.1| two-component histidine kinase ... 82.8 1e-14
gi|111223229|ref|YP_714023.1| putative transmembrane sensory tra... 82.8 1e-14
gi|160882233|ref|ZP_02063236.1| hypothetical protein BACOVA_0017... 82.8 1e-14
gi|237716433|ref|ZP_04546914.1| two-component system sensor hist... 82.8 2e-14
gi|111020129|ref|YP_703101.1| sensor kinase, two-component syste... 82.8 2e-14
gi|41407199|ref|NP_960035.1| hypothetical protein MAP1101 [Mycob... 82.4 2e-14
gi|254775853|ref|ZP_05217369.1| hypothetical protein MaviaA2_144... 82.4 2e-14
gi|88855870|ref|ZP_01130532.1| two-component system, sensor prot... 82.4 2e-14
gi|118464100|ref|YP_882588.1| hypothetical protein MAV_3405 [Myc... 82.4 2e-14
gi|182435927|ref|YP_001823646.1| putative two-component system s... 82.4 2e-14
gi|21223764|ref|NP_629543.1| two-component sensor kinase [Strept... 82.0 2e-14
gi|326776551|ref|ZP_08235816.1| integral membrane sensor signal ... 82.0 3e-14
>gi|57996832|emb|CAI45378.1| artificial two-component regulatory system sensor kinase [Mycobacterium
tuberculosis H37Rv]
Length=363
Score = 298 bits (764), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%)
Query 1 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 60
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY
Sbjct 1 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 60
Query 61 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 120
LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA
Sbjct 61 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 120
Query 121 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 156
HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
Sbjct 121 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 156
>gi|15607741|ref|NP_215115.1| two component sensor kinase [Mycobacterium tuberculosis H37Rv]
gi|31791783|ref|NP_854276.1| two component sensor kinase [Mycobacterium bovis AF2122/97]
gi|121636519|ref|YP_976742.1| putative two component sensor kinase (first part) [Mycobacterium
bovis BCG str. Pasteur 1173P2]
27 more sequence titles
Length=156
Score = 298 bits (762), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%)
Query 1 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 60
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY
Sbjct 1 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 60
Query 61 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 120
LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA
Sbjct 61 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 120
Query 121 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 156
HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
Sbjct 121 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 156
>gi|167969025|ref|ZP_02551302.1| putative two component sensor kinase [Mycobacterium tuberculosis
H37Ra]
gi|254549558|ref|ZP_05140005.1| putative two component sensor kinase [Mycobacterium tuberculosis
'98-R604 INH-RIF-EM']
gi|294996115|ref|ZP_06801806.1| putative two component sensor kinase [Mycobacterium tuberculosis
210]
6 more sequence titles
Length=176
Score = 298 bits (762), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%)
Query 1 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 60
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY
Sbjct 21 MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY 80
Query 61 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 120
LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA
Sbjct 81 LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA 140
Query 121 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 156
HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
Sbjct 141 HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS 176
>gi|289568535|ref|ZP_06448762.1| two component system sensor kinase [Mycobacterium tuberculosis
T17]
gi|289542289|gb|EFD45937.1| two component system sensor kinase [Mycobacterium tuberculosis
T17]
Length=175
Score = 276 bits (705), Expect = 1e-72, Method: Compositional matrix adjust.
Identities = 143/144 (99%), Positives = 143/144 (99%), Gaps = 0/144 (0%)
Query 13 VVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDR 72
VVQFRD AHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDR
Sbjct 32 VVQFRDPAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDR 91
Query 73 IRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHE 132
IRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHE
Sbjct 92 IRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHE 151
Query 133 LRTPLALLTTELELRCAGPDPPTS 156
LRTPLALLTTELELRCAGPDPPTS
Sbjct 152 LRTPLALLTTELELRCAGPDPPTS 175
>gi|336177575|ref|YP_004582950.1| integral membrane sensor signal transduction histidine kinase
[Frankia symbiont of Datisca glomerata]
gi|334858555|gb|AEH09029.1| integral membrane sensor signal transduction histidine kinase
[Frankia symbiont of Datisca glomerata]
Length=533
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 56/113 (50%), Positives = 75/113 (67%), Gaps = 4/113 (3%)
Query 35 DITADLVRELVTILPIVLV-IAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLP 93
D D VR+++ + + +V ++A+AA++LS AALRPV+R+R A + DT L
Sbjct 144 DAAEDRVRDVMVLASVPMVAVSALAAWVLSGAALRPVERMRRQAAAMGVA---DTGGRLE 200
Query 94 VPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
VPPT DEIA LA T+N +L RL A A ++ FVADA HELRTPL +L ELEL
Sbjct 201 VPPTRDEIAALADTMNDLLDRLHAARARDRAFVADAGHELRTPLTILKAELEL 253
>gi|158315648|ref|YP_001508156.1| integral membrane sensor signal transduction histidine kinase
[Frankia sp. EAN1pec]
gi|158111053|gb|ABW13250.1| integral membrane sensor signal transduction histidine kinase
[Frankia sp. EAN1pec]
Length=476
Score = 93.6 bits (231), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 56/113 (50%), Positives = 73/113 (65%), Gaps = 4/113 (3%)
Query 35 DITADLVRE-LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLP 93
D D VR +V+ ++ ++ +AA+LLS AALRPVDR+R ++ + D+ A L
Sbjct 149 DSAEDRVRNIMVSATAPMVALSGLAAWLLSGAALRPVDRMRRQTAAISES---DSSAELD 205
Query 94 VPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
VPPT DEIA LA T+N +L RL A A ++ FVADA HELRTPL L ELEL
Sbjct 206 VPPTRDEIAALAATMNNLLRRLHAARARDRAFVADAGHELRTPLTNLKAELEL 258
>gi|229494403|ref|ZP_04388166.1| sensor kinase, two-component system [Rhodococcus erythropolis
SK121]
gi|229318765|gb|EEN84623.1| sensor kinase, two-component system [Rhodococcus erythropolis
SK121]
Length=447
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 51/104 (50%), Positives = 69/104 (67%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
P+VL +AA A Y L +AL PV+RIRA ++++ + +PVP +DEIA LATT+
Sbjct 159 PLVLGLAAFATYRLVGSALAPVERIRARVASISSGRQGER---VPVPSGNDEIARLATTM 215
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N ML RL +Q+FV+DASHELR+PL+ +TT LEL PD
Sbjct 216 NDMLARLDEGALAQQRFVSDASHELRSPLSTITTALELAHRRPD 259
>gi|226304508|ref|YP_002764466.1| two-component histidine kinase [Rhodococcus erythropolis PR4]
gi|226183623|dbj|BAH31727.1| putative two-component histidine kinase [Rhodococcus erythropolis
PR4]
Length=484
Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 51/104 (50%), Positives = 69/104 (67%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
P+VL +AA A Y L +AL PV+RIRA ++++ + +PVP +DEIA LATT+
Sbjct 191 PLVLGLAAFATYRLVGSALAPVERIRARVASISSGRQGER---VPVPSGNDEIARLATTM 247
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N ML RL +Q+FV+DASHELR+PL+ +TT LEL PD
Sbjct 248 NDMLARLDEGALAQQRFVSDASHELRSPLSTITTALELAHRRPD 291
>gi|229489858|ref|ZP_04383714.1| sensor kinase, two-component system [Rhodococcus erythropolis
SK121]
gi|229323208|gb|EEN88973.1| sensor kinase, two-component system [Rhodococcus erythropolis
SK121]
Length=380
Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 49/109 (45%), Positives = 70/109 (65%), Gaps = 3/109 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
L + P+V+ + A+A Y L AAL PV+RIR +++ + D +PVP + DEIA
Sbjct 81 LAIVGPVVVALVALATYRLVGAALSPVERIRTRVASISNS---DLGERIPVPRSRDEIAR 137
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T+N ML RLQ +Q+FV+DASHELR+PL+ +T LEL + P+
Sbjct 138 LAVTMNRMLERLQAGQRAQQRFVSDASHELRSPLSTITAALELAASRPE 186
>gi|257126115|ref|YP_003164229.1| histidine kinase [Leptotrichia buccalis C-1013-b]
gi|257050054|gb|ACV39238.1| histidine kinase [Leptotrichia buccalis C-1013-b]
Length=454
Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/99 (38%), Positives = 60/99 (61%), Gaps = 2/99 (2%)
Query 47 ILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLAT 106
+LP LV +A++ Y +++ A +P+++IR A + + D + + +DEI LA
Sbjct 160 VLPFFLVFSAISGYFITKKAFKPIEKIREAVEKIN--EGNDLTQRINIGEGNDEIYTLAN 217
Query 107 TLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELE 145
T +TM RLQ + E QF +D SHELRTP+A++ +E E
Sbjct 218 TFDTMFDRLQNSFEREAQFTSDVSHELRTPVAIIISECE 256
>gi|260888930|ref|ZP_05900193.1| sensor histidine kinase [Leptotrichia hofstadii F0254]
gi|260861377|gb|EEX75877.1| sensor histidine kinase [Leptotrichia hofstadii F0254]
Length=454
Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 61/100 (61%), Gaps = 2/100 (2%)
Query 47 ILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLAT 106
+LP L+ +A++ Y +++ A +P+++IR AA+ + D + + +DEI LA
Sbjct 160 VLPFFLLFSAISGYFITKKAFKPIEKIRGAAEKIN--EGNDLTQRINIGEGNDEIYTLAN 217
Query 107 TLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
T +TM RLQ + E QF +D SHELRTP++++ +E E
Sbjct 218 TFDTMFDRLQSSFEREAQFTSDVSHELRTPVSIIISECEY 257
>gi|226349582|ref|YP_002776696.1| two-component histidine kinase [Rhodococcus opacus B4]
gi|226245497|dbj|BAH55844.1| two-component histidine kinase [Rhodococcus opacus B4]
Length=472
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 51/104 (50%), Positives = 68/104 (66%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
PIV+ AVA Y L AALRPV+RIRA +++T D +PVP DE+A LA T+
Sbjct 178 PIVIGFVAVATYRLIGAALRPVERIRARVASISTD---QLDERVPVPAARDEVADLAVTM 234
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N+ML RL+ +++FV DASHELR+PLA +T LEL + P+
Sbjct 235 NSMLARLEAGHLAQRRFVGDASHELRSPLATITAALELAQSRPE 278
>gi|344330335|gb|EGW41636.1| HAMP domain protein [Desulfosporosinus sp. OT]
Length=461
Score = 87.8 bits (216), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 40/89 (45%), Positives = 60/89 (68%), Gaps = 3/89 (3%)
Query 52 LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTM 111
+ I+ A YL+SR L P+DRI AAQ+++ D + + V TDDE++ LA T N M
Sbjct 171 IAISLFAGYLMSRRMLYPIDRITRAAQSISVN---DLNRRIEVSQTDDELSRLAKTFNEM 227
Query 112 LTRLQRALAHEQQFVADASHELRTPLALL 140
+ RLQ + ++QFV+DASHELRTP++++
Sbjct 228 IERLQLSFEKQKQFVSDASHELRTPISVI 256
>gi|94967341|ref|YP_589389.1| periplasmic sensor signal transduction histidine kinase [Candidatus
Koribacter versatilis Ellin345]
gi|94549391|gb|ABF39315.1| periplasmic sensor signal transduction histidine kinase [Candidatus
Koribacter versatilis Ellin345]
Length=484
Score = 87.4 bits (215), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 47/103 (46%), Positives = 67/103 (66%), Gaps = 3/103 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
+ ++P ++IAAV +Y SR ALR VD I A A+++ + + LP T+DE+
Sbjct 166 FLFLVPCFVLIAAVGSYYFSRRALRSVDEITAMARSI---HERNLNQRLPPLQTNDELQR 222
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
L+ TLN ML+R++ A +QF ADASHELRTPL+L+ TE EL
Sbjct 223 LSDTLNEMLSRIEAAFTRTRQFTADASHELRTPLSLIRTEAEL 265
>gi|340752079|ref|ZP_08688889.1| sensor histidine kinase [Fusobacterium mortiferum ATCC 9817]
gi|229421048|gb|EEO36095.1| sensor histidine kinase [Fusobacterium mortiferum ATCC 9817]
Length=443
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 42/122 (35%), Positives = 73/122 (60%), Gaps = 7/122 (5%)
Query 29 LRGLTDDITADLVRELVT-----ILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTT 83
+RG+ DI + + +++ ILPI+++++ V Y +++ A PV +I+ AQ +T +
Sbjct 127 IRGVFSDIQINQLTQIIVTGAFLILPILVILSTVIGYFITKKAFLPVKKIQETAQNITES 186
Query 84 PHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTE 143
+ + +P DEI LA T++ ML RL ++ E+QF +DASHELRTP+ ++ E
Sbjct 187 N--ELSLRIGLPKGRDEITKLANTIDEMLERLDKSFQKEKQFTSDASHELRTPVTVILAE 244
Query 144 LE 145
E
Sbjct 245 SE 246
>gi|300786953|ref|YP_003767244.1| two-component system histidine kinase [Amycolatopsis mediterranei
U32]
gi|299796467|gb|ADJ46842.1| two-component system histidine kinase [Amycolatopsis mediterranei
U32]
Length=454
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 49/118 (42%), Positives = 71/118 (61%), Gaps = 3/118 (2%)
Query 32 LTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAP 91
L +D+T + L + +++ A+LL+ AALRPV+++R ++ T D P
Sbjct 146 LQNDLTRRVTWWLSGAAAVTVLVGGWGAWLLAGAALRPVEQLRREVSGISET---DPSTP 202
Query 92 LPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCA 149
+ VP T DE+A LA T+N +L R+ L ++QFVADASHE+RTPL L T LEL A
Sbjct 203 VRVPGTGDEVAALAETMNALLARISAGLTRQRQFVADASHEVRTPLTNLRTTLELAGA 260
>gi|340528444|gb|AEK43649.1| two-component system histidine kinase [Amycolatopsis mediterranei
S699]
Length=494
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 49/118 (42%), Positives = 71/118 (61%), Gaps = 3/118 (2%)
Query 32 LTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAP 91
L +D+T + L + +++ A+LL+ AALRPV+++R ++ T D P
Sbjct 146 LQNDLTRRVTWWLSGAAAVTVLVGGWGAWLLAGAALRPVEQLRREVSGISET---DPSTP 202
Query 92 LPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCA 149
+ VP T DE+A LA T+N +L R+ L ++QFVADASHE+RTPL L T LEL A
Sbjct 203 VRVPGTGDEVAALAETMNALLARISAGLTRQRQFVADASHEVRTPLTNLRTTLELAGA 260
>gi|111025332|ref|YP_707752.1| sensor histidine kinase [Rhodococcus jostii RHA1]
gi|110824311|gb|ABG99594.1| sensor histidine kinase [Rhodococcus jostii RHA1]
Length=469
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 50/104 (49%), Positives = 67/104 (65%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
P++ +IAAV Y L R +LR V+ IR T+++T D +PVP DEIA LA T+
Sbjct 180 PVIALIAAVVTYKLVRRSLRSVEHIRTQVATISST---DLAERIPVPTPRDEIAALARTM 236
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N MLTRL+ +++FV DASHELR+PLA +T LEL A P+
Sbjct 237 NDMLTRLEAGHTAQRRFVGDASHELRSPLATVTMALELADARPE 280
>gi|119715850|ref|YP_922815.1| ATPase domain-containing protein [Nocardioides sp. JS614]
gi|119536511|gb|ABL81128.1| ATP-binding region, ATPase domain protein [Nocardioides sp. JS614]
Length=455
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 56/121 (47%), Positives = 74/121 (62%), Gaps = 2/121 (1%)
Query 32 LTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAP 91
L + TA +V L+ P+VLV +Y L AL PV+RIR+ T+ T TD
Sbjct 152 LVSESTAIIVGLLMVGYPLVLVAVGGTSYWLVGRALAPVERIRSRVATIHGTSKA-TDR- 209
Query 92 LPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGP 151
+PVP T DEI+ LA T+N ML+RL+ A A ++QFVADASHELR+PLA + E+ P
Sbjct 210 VPVPDTHDEISRLAETMNAMLSRLEAASASQRQFVADASHELRSPLATIRAVHEIAVLHP 269
Query 152 D 152
D
Sbjct 270 D 270
>gi|302870966|ref|YP_003839602.1| integral membrane sensor signal transduction histidine kinase
[Caldicellulosiruptor obsidiansis OB47]
gi|302573825|gb|ADL41616.1| integral membrane sensor signal transduction histidine kinase
[Caldicellulosiruptor obsidiansis OB47]
Length=460
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 45/106 (43%), Positives = 63/106 (60%), Gaps = 3/106 (2%)
Query 33 TDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPL 92
T I +L + +PI +IA Y+L++ AL+P+D I A+T+ H D L
Sbjct 150 TRRIMNNLKNVIFLSIPIPFLIAVAGGYILAKKALKPIDDITTMARTI---GHTDLSKRL 206
Query 93 PVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLA 138
P T+DEI LA T + ML RL+ A E++F++DASHELRTPLA
Sbjct 207 NFPNTNDEIGRLALTFDEMLERLENAFKRERRFLSDASHELRTPLA 252
>gi|297160787|gb|ADI10499.1| putative two-component system sensor kinase [Streptomyces bingchenggensis
BCW-1]
Length=485
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 48/110 (44%), Positives = 70/110 (64%), Gaps = 2/110 (1%)
Query 40 LVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDD 99
+ R ++ LP +LV+ A +L++R ALRPV+ IR +T + D +P P + D
Sbjct 193 VTRVMLIGLPCLLVVVAGVTWLVTRRALRPVEGIRGEMAEITASG--DLSRRVPQPDSHD 250
Query 100 EIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCA 149
EIA LA T N LT L+R++ + +FVADASHELR+P+A L T+LE+ A
Sbjct 251 EIARLAATTNETLTALERSVERQHRFVADASHELRSPIASLRTQLEVAVA 300
>gi|297561738|ref|YP_003680712.1| integral membrane sensor signal transduction histidine kinase
[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111]
gi|296846186|gb|ADH68206.1| integral membrane sensor signal transduction histidine kinase
[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111]
Length=475
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 47/110 (43%), Positives = 67/110 (61%), Gaps = 3/110 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
LV + ++L + ALRPV+ IRA TL+ + D LPVP +DDEIA
Sbjct 168 LVVMSCVLLATTGFVIWHGVGRALRPVEEIRAQLDTLSVS---DLHRRLPVPNSDDEIAH 224
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDP 153
LA T N L R++ +A +++FV+DASHELR P+A + T+LE+ + PDP
Sbjct 225 LARTANHSLERMEEGMARQRRFVSDASHELRNPIAGMRTKLEVELSDPDP 274
>gi|333979456|ref|YP_004517401.1| integral membrane sensor signal transduction histidine kinase
[Desulfotomaculum kuznetsovii DSM 6115]
gi|333822937|gb|AEG15600.1| integral membrane sensor signal transduction histidine kinase
[Desulfotomaculum kuznetsovii DSM 6115]
Length=459
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 47/107 (44%), Positives = 65/107 (61%), Gaps = 3/107 (2%)
Query 48 LPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATT 107
+P+ LV+AA L+R AL+P+D I A A+ ++ T D L +P +DE+ L T
Sbjct 168 IPMTLVMAAGGGIFLARRALQPIDEIAAKARQISAT---DLSRRLDLPHGNDEVGHLVAT 224
Query 108 LNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPP 154
L+ ML RL RA ++QF ADASHELRTPLA++ +E E P P
Sbjct 225 LDEMLDRLDRAFQRQRQFTADASHELRTPLAVIRSEAEAALKRPHSP 271
>gi|320008510|gb|ADW03360.1| integral membrane sensor signal transduction histidine kinase
[Streptomyces flavogriseus ATCC 33331]
Length=477
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 50/115 (44%), Positives = 75/115 (66%), Gaps = 3/115 (2%)
Query 39 DLVRE-LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D VR ++T LP++L++ A +L++R ALRPV+ IR +T + D +P P +
Sbjct 181 DTVRNSMLTGLPLMLLVVAGVTWLVTRRALRPVEGIRRELAAITASE--DLGRRVPEPDS 238
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
DEIA LA T N LT L+ ++ +++FVADASHELR+P+A L T+LE+ A P+
Sbjct 239 RDEIARLARTTNETLTVLEASVGRQRRFVADASHELRSPIASLRTQLEVGAAHPE 293
>gi|296170766|ref|ZP_06852338.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295894581|gb|EFG74318.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=460
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 48/104 (47%), Positives = 66/104 (64%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
PIV+ +AA A + L R +LR VD IRA ++ + D +PVP DEIA LA T+
Sbjct 169 PIVIAVAAGATFWLVRRSLRSVDAIRARVAEISAS---DLAERVPVPNGRDEIAALAVTM 225
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N ML+R++ +Q+FV DASHELR+PLA + + LE+ A PD
Sbjct 226 NRMLSRIEAGHRAQQRFVGDASHELRSPLATIISGLEVAEAHPD 269
>gi|284041763|ref|YP_003392103.1| integral membrane sensor signal transduction histidine kinase
[Conexibacter woesei DSM 14684]
gi|283945984|gb|ADB48728.1| integral membrane sensor signal transduction histidine kinase
[Conexibacter woesei DSM 14684]
Length=453
Score = 84.7 bits (208), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 46/80 (58%), Positives = 55/80 (69%), Gaps = 3/80 (3%)
Query 67 LRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFV 126
LRPV+R+RA A ++ D A LP+PP DEI L TLN ML RL AL E++FV
Sbjct 182 LRPVERMRARAAAVS---EEDPAARLPIPPARDEIRRLGETLNAMLDRLHGALDRERRFV 238
Query 127 ADASHELRTPLALLTTELEL 146
ADASHELRTPL++L ELEL
Sbjct 239 ADASHELRTPLSILKAELEL 258
>gi|342858650|ref|ZP_08715305.1| hypothetical protein MCOL_07231 [Mycobacterium colombiense CECT
3035]
gi|342134354|gb|EGT87534.1| hypothetical protein MCOL_07231 [Mycobacterium colombiense CECT
3035]
Length=441
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 46/104 (45%), Positives = 67/104 (65%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
P+++ + A A Y L R +L+ VD IR ++T+ D +PVP ++DEIA LA T+
Sbjct 152 PVIVGVVAAATYWLVRRSLQSVDAIRTRVADISTS---DLAERVPVPDSNDEIAALAVTM 208
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N ML+RL+ +Q+FV DASHELR+PLA + + LE+ A PD
Sbjct 209 NEMLSRLEAGHRAQQRFVGDASHELRSPLATIISGLEVAEAHPD 252
>gi|29826612|ref|NP_821246.1| two-component system sensor kinase [Streptomyces avermitilis
MA-4680]
gi|29603708|dbj|BAC67781.1| putative two-component system sensor kinase [Streptomyces avermitilis
MA-4680]
Length=551
Score = 84.0 bits (206), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 52/115 (46%), Positives = 71/115 (62%), Gaps = 3/115 (2%)
Query 38 ADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
+L RELV +P+ + A A+L +R ALRPV+ IRA ++T D + VP T
Sbjct 224 GELDRELVVAVPLATALVAGVAWLATRRALRPVEAIRARTASVTAA---DPRERVEVPDT 280
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
DE+A LA T+N L RL+ A +++FVADA+HELR+PLA L LE+ A PD
Sbjct 281 ADEVAELALTINATLQRLEEAATAQRRFVADAAHELRSPLATLLAGLEVATAYPD 335
>gi|222528318|ref|YP_002572200.1| histidine kinase [Caldicellulosiruptor bescii DSM 6725]
gi|222455165|gb|ACM59427.1| histidine kinase [Caldicellulosiruptor bescii DSM 6725]
Length=461
Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 47/115 (41%), Positives = 65/115 (57%), Gaps = 7/115 (6%)
Query 27 GALR----GLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTT 82
G LR LT + +L + +P+ +IA YLL++ AL+P+D I A+T T
Sbjct 139 GWLRIGRPSLTKRVLQNLKNVIFLSIPLPFLIAIWGGYLLAKKALKPIDDI---AKTART 195
Query 83 TPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPL 137
H D L P +DEI LA T + ML RL+ A E++F++DASHELRTPL
Sbjct 196 IGHTDLSKRLNFPKVEDEIGRLAMTFDEMLDRLENAFKRERRFLSDASHELRTPL 250
>gi|300790442|ref|YP_003770733.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
gi|299799956|gb|ADJ50331.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
gi|340532126|gb|AEK47331.1| two-component system sensor kinase [Amycolatopsis mediterranei
S699]
Length=457
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 46/102 (46%), Positives = 67/102 (66%), Gaps = 3/102 (2%)
Query 51 VLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNT 110
+L IA +A Y +ALRPV+R+R ++T D A +P+PP DE+ LA TLN
Sbjct 171 LLAIAGLAVYRAVGSALRPVERMRRTVAEISTR---DLAARVPLPPGGDEVQRLAVTLNE 227
Query 111 MLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
ML+RL A A +++FVADASHELR+PL+ ++T L++ P+
Sbjct 228 MLSRLASAQAAQRRFVADASHELRSPLSTISTALDVSGRHPE 269
>gi|311897137|dbj|BAJ29545.1| putative two-component system sensor kinase [Kitasatospora setae
KM-6054]
Length=547
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 46/110 (42%), Positives = 72/110 (66%), Gaps = 3/110 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
L LP+++ + A+ + ++ ALRPV+ IR+ +T D +PVP T DE++
Sbjct 242 LAVGLPLLVALVAMVTWRVTGRALRPVEAIRSEVAEITGH---DLHRRVPVPRTGDEVSR 298
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDP 153
LA T+N+ L RL+ A +++F+ADASHELR+P+A+L T+LE+ A PDP
Sbjct 299 LAATVNSTLDRLEDAGQRQRRFIADASHELRSPIAVLRTQLEVALAHPDP 348
>gi|83590321|ref|YP_430330.1| periplasmic sensor signal transduction histidine kinase [Moorella
thermoacetica ATCC 39073]
gi|83573235|gb|ABC19787.1| periplasmic sensor signal transduction histidine kinase [Moorella
thermoacetica ATCC 39073]
Length=459
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/98 (44%), Positives = 63/98 (65%), Gaps = 3/98 (3%)
Query 48 LPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATT 107
+P+ L++AA L+R AL+P+DRI A A+ ++ T D L +P +DE+ L T
Sbjct 168 IPMTLLVAAGGGIFLARRALQPIDRIAAKARQISAT---DLSRRLDLPHGNDEVGHLVAT 224
Query 108 LNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELE 145
L+ ML RL RA ++QF ADASHE RTPLA++ ++ E
Sbjct 225 LDEMLDRLDRAFQRQRQFTADASHEFRTPLAVIRSQAE 262
>gi|336402308|ref|ZP_08583046.1| hypothetical protein HMPREF0127_00359 [Bacteroides sp. 1_1_30]
gi|335936253|gb|EGM98187.1| hypothetical protein HMPREF0127_00359 [Bacteroides sp. 1_1_30]
Length=455
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|298481286|ref|ZP_06999479.1| two-component system response regulator sensor kinase [Bacteroides
sp. D22]
gi|298272490|gb|EFI14058.1| two-component system response regulator sensor kinase [Bacteroides
sp. D22]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|237720753|ref|ZP_04551234.1| two-component system sensor histidine kinase [Bacteroides sp.
2_2_4]
gi|229449588|gb|EEO55379.1| two-component system sensor histidine kinase [Bacteroides sp.
2_2_4]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|299145539|ref|ZP_07038607.1| putative two-component regulator sensor kinase [Bacteroides sp.
3_1_23]
gi|298516030|gb|EFI39911.1| putative two-component regulator sensor kinase [Bacteroides sp.
3_1_23]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|315918676|ref|ZP_07914916.1| two-component system sensor histidine kinase [Bacteroides sp.
D2]
gi|313692551|gb|EFS29386.1| two-component system sensor histidine kinase [Bacteroides sp.
D2]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|336416202|ref|ZP_08596538.1| hypothetical protein HMPREF1017_03646 [Bacteroides ovatus 3_8_47FAA]
gi|335938933|gb|EGN00812.1| hypothetical protein HMPREF1017_03646 [Bacteroides ovatus 3_8_47FAA]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|226228543|ref|YP_002762649.1| two-component histidine kinase [Gemmatimonas aurantiaca T-27]
gi|226091734|dbj|BAH40179.1| two-component histidine kinase [Gemmatimonas aurantiaca T-27]
Length=496
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 48/113 (43%), Positives = 72/113 (64%), Gaps = 4/113 (3%)
Query 35 DITADLVRELVTI-LPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLP 93
D+ VRE + I +PI L++A L+ A+LRPVD +RA A+ +T + + LP
Sbjct 183 DVLFARVRETMWIGVPIALLLAMAGGLGLAAASLRPVDAMRAQAEQITAS---NLHERLP 239
Query 94 VPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
VP T+DE++ L+ T N +L R++ A ++F ADASHELRTP+A++ E EL
Sbjct 240 VPSTEDELSRLSRTFNALLDRVEDAFEQRRRFTADASHELRTPVAIVIGESEL 292
>gi|111223229|ref|YP_714023.1| putative transmembrane sensory transduction histidine kinase
for metal resistance [Frankia alni ACN14a]
gi|111150761|emb|CAJ62463.1| putative transmembrane sensory transduction histidine kinase
for metal resistance [Frankia alni ACN14a]
Length=519
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 54/115 (47%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
Query 35 DITADLVRE-LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAP-- 91
D D VR +V ++ ++ +AA+LLS AALRPVDR+R A + +
Sbjct 161 DRAEDRVRNVMVAATAPLIALSGLAAWLLSGAALRPVDRMRRQAAEMAASDLGTAGGGFQ 220
Query 92 LPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
L VP T DEIA LA T+N +L RL A A ++ FVADA HELRTPL +L ELEL
Sbjct 221 LAVPATRDEIAALARTMNDLLARLHAARARDRAFVADAGHELRTPLTVLRAELEL 275
>gi|160882233|ref|ZP_02063236.1| hypothetical protein BACOVA_00179 [Bacteroides ovatus ATCC 8483]
gi|156112385|gb|EDO14130.1| hypothetical protein BACOVA_00179 [Bacteroides ovatus ATCC 8483]
Length=455
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|237716433|ref|ZP_04546914.1| two-component system sensor histidine kinase [Bacteroides sp.
D1]
gi|262408033|ref|ZP_06084581.1| two-component system sensor histidine kinase [Bacteroides sp.
2_1_22]
gi|294643326|ref|ZP_06721150.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Bacteroides
ovatus SD CC 2a]
gi|294806112|ref|ZP_06764965.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Bacteroides
xylanisolvens SD CC 1b]
gi|229444080|gb|EEO49871.1| two-component system sensor histidine kinase [Bacteroides sp.
D1]
gi|262354841|gb|EEZ03933.1| two-component system sensor histidine kinase [Bacteroides sp.
2_1_22]
gi|292641332|gb|EFF59526.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Bacteroides
ovatus SD CC 2a]
gi|294446700|gb|EFG15314.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Bacteroides
xylanisolvens SD CC 1b]
Length=455
Score = 82.8 bits (203), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 43/109 (40%), Positives = 67/109 (62%), Gaps = 4/109 (3%)
Query 39 DLVRELVTILPIV-LVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPT 97
D +R ++ +L I L + V Y+LSR+ L+P+ I A+ +T + D LPV
Sbjct 152 DALRNMLILLFIGGLSVLVVVGYILSRSTLKPIRNIVKEAEKITASH---IDKRLPVKNE 208
Query 98 DDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELEL 146
DE+ L+TT N +L RL+++ ++ FV++ SHELRTP+A LT EL+L
Sbjct 209 QDELGELSTTFNALLERLEKSFNSQKMFVSNVSHELRTPMAALTAELDL 257
>gi|111020129|ref|YP_703101.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
gi|110819659|gb|ABG94943.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
Length=472
Score = 82.8 bits (203), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/104 (46%), Positives = 65/104 (63%), Gaps = 3/104 (2%)
Query 49 PIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTL 108
P++ ++AAV Y L R +LR V+ IR T+++T D +PVP DEIA L T+
Sbjct 178 PVIALVAAVVTYKLVRRSLRSVEHIRTQVATISST---DLGERIPVPAPRDEIAALTRTM 234
Query 109 NTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N ML RL+ +++FV DASHELR+PLA +T LEL A P+
Sbjct 235 NDMLARLEAGHTAQRRFVGDASHELRSPLATVTMALELADARPE 278
>gi|41407199|ref|NP_960035.1| hypothetical protein MAP1101 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41395550|gb|AAS03418.1| hypothetical protein MAP_1101 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336461547|gb|EGO40414.1| signal transduction histidine kinase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=467
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/109 (44%), Positives = 67/109 (62%), Gaps = 3/109 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
L T P+++ +AA A Y L R +L+ VD IRA ++ + D +PVP DEIA
Sbjct 171 LATTAPVIVAVAAGATYWLVRRSLKSVDAIRARVADISAS---DLAERVPVPDGRDEIAA 227
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T+N ML+RL+ +Q+FV DASHELR+PL + + LE+ A P+
Sbjct 228 LAVTMNEMLSRLEAGHRAQQRFVGDASHELRSPLTTIISGLEVAEAHPE 276
>gi|254775853|ref|ZP_05217369.1| hypothetical protein MaviaA2_14445 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=454
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/109 (45%), Positives = 66/109 (61%), Gaps = 3/109 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
L T P+++ +AA A Y L R +L+ VD IRA +T D +PVP DEIA
Sbjct 158 LATTAPVIVAVAAGATYWLVRRSLKSVDAIRA---RVTDISASDLAERVPVPDGRDEIAA 214
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T+N ML+RL+ +Q+FV DASHELR+PL + + LE+ A P+
Sbjct 215 LAVTMNEMLSRLEAGHRAQQRFVGDASHELRSPLTTIISGLEVAEAHPE 263
>gi|88855870|ref|ZP_01130532.1| two-component system, sensor protein [marine actinobacterium
PHSC20C1]
gi|88814737|gb|EAR24597.1| two-component system, sensor protein [marine actinobacterium
PHSC20C1]
Length=449
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/140 (43%), Positives = 82/140 (59%), Gaps = 17/140 (12%)
Query 8 AGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIA-AVAAYLLSRAA 66
AGA TV R A + ALRGL ++ I IVL+ A+A+++L+ A
Sbjct 127 AGAWTVWSARSTAA---SELALRGLG---------SVLLIAGIVLLAGFAIASWVLATVA 174
Query 67 LRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFV 126
LRPV+ +R A+ + D++A LPV P DE+A LA TLN L + + A E+Q V
Sbjct 175 LRPVNAMRRKAEAFSA----DSEATLPVGPARDELAALAETLNEFLAQTRAATEREKQMV 230
Query 127 ADASHELRTPLALLTTELEL 146
+DA+HELRTPLA L T+LEL
Sbjct 231 SDAAHELRTPLAALKTQLEL 250
>gi|118464100|ref|YP_882588.1| hypothetical protein MAV_3405 [Mycobacterium avium 104]
gi|118165387|gb|ABK66284.1| conserved hypothetical protein [Mycobacterium avium 104]
Length=467
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/109 (44%), Positives = 67/109 (62%), Gaps = 3/109 (2%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
L T P+++ +AA A Y L R +L+ VD IRA ++ + D +PVP DEIA
Sbjct 171 LATTAPVIVAVAAGATYWLVRRSLKSVDAIRARVADISAS---DLAERVPVPDGRDEIAA 227
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T+N ML+RL+ +Q+FV DASHELR+PL + + LE+ A P+
Sbjct 228 LAVTMNEMLSRLEAGHRAQQRFVGDASHELRSPLTTIISGLEVAEAHPE 276
>gi|182435927|ref|YP_001823646.1| putative two-component system sensor kinase [Streptomyces griseus
subsp. griseus NBRC 13350]
gi|178464443|dbj|BAG18963.1| putative two-component system sensor kinase [Streptomyces griseus
subsp. griseus NBRC 13350]
Length=482
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/109 (45%), Positives = 72/109 (67%), Gaps = 2/109 (1%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
++T LP++LV+ A +L++R ALRPV+ IR +T + D +P P + DEIA
Sbjct 194 MLTGLPLLLVVVAGVTWLVTRRALRPVEGIRRELAAITASE--DLARRVPEPGSRDEIAA 251
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T N LT L+ ++ +++FVADASHELR+P+A L T+LE+ A P+
Sbjct 252 LARTTNETLTVLEASVERQRRFVADASHELRSPIASLRTQLEVAEAHPE 300
>gi|21223764|ref|NP_629543.1| two-component sensor kinase [Streptomyces coelicolor A3(2)]
gi|289769036|ref|ZP_06528414.1| two-component sensor kinase [Streptomyces lividans TK24]
gi|6808397|emb|CAB70634.1| probable two-component sensor kinase [Streptomyces coelicolor
A3(2)]
gi|289699235|gb|EFD66664.1| two-component sensor kinase [Streptomyces lividans TK24]
Length=478
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 46/105 (44%), Positives = 67/105 (64%), Gaps = 2/105 (1%)
Query 48 LPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATT 107
P++L + A +L++R ALRPV+ IR +T + D +PVP T DE+A LATT
Sbjct 192 FPLLLAVVAWVTWLVTRRALRPVEGIRREMAAITASE--DLARRVPVPGTHDEVARLATT 249
Query 108 LNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
N L L+ ++ ++ FVADASHELR+P+A L T+LE+ A P+
Sbjct 250 TNETLAALESSVERQRGFVADASHELRSPIASLRTQLEVAAAHPE 294
>gi|326776551|ref|ZP_08235816.1| integral membrane sensor signal transduction histidine kinase
[Streptomyces cf. griseus XylebKG-1]
gi|326656884|gb|EGE41730.1| integral membrane sensor signal transduction histidine kinase
[Streptomyces griseus XylebKG-1]
Length=482
Score = 82.0 bits (201), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 48/109 (45%), Positives = 72/109 (67%), Gaps = 2/109 (1%)
Query 44 LVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAW 103
++T LP++LV+ A +L++R ALRPV+ IR +T + D +P P + DEIA
Sbjct 194 MLTGLPLLLVVVAGVTWLVTRRALRPVEGIRRELAAITASE--DLARRVPEPGSRDEIAA 251
Query 104 LATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPD 152
LA T N LT L+ ++ +++FVADASHELR+P+A L T+LE+ A P+
Sbjct 252 LARTTNETLTVLEASVERQRRFVADASHELRSPIASLRTQLEVAEAHPE 300
Lambda K H
0.320 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 130065254832
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40