BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0617

Length=133
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607757|ref|NP_215131.1|  hypothetical protein Rv0617 [Mycoba...   262    2e-68
gi|240169388|ref|ZP_04748047.1|  hypothetical protein MkanA1_0874...   211    3e-53
gi|289749117|ref|ZP_06508495.1|  conserved hypothetical protein [...   190    8e-47
gi|336179654|ref|YP_004585029.1|  PIN domain-containing protein f...   170    5e-41
gi|324997204|ref|ZP_08118316.1|  toxin [Pseudonocardia sp. P1]         117    4e-25
gi|227876599|ref|ZP_03994709.1|  conserved hypothetical protein [...  95.5    2e-18
gi|225874392|ref|YP_002755851.1|  Mycobacterium tuberculosis PIN ...  88.2    4e-16
gi|294339103|emb|CAZ87457.1|  conserved hypothetical protein; put...  85.9    2e-15
gi|113953974|ref|YP_729372.1|  hypothetical protein sync_0135 [Sy...  85.5    2e-15
gi|241518561|ref|YP_002979189.1|  PIN domain protein family prote...  85.1    3e-15
gi|333815879|gb|AEG08546.1|  PIN domain protein family protein [S...  84.3    5e-15
gi|254420497|ref|ZP_05034221.1|  Mycobacterium tuberculosis PIN d...  83.6    9e-15
gi|344199817|ref|YP_004784143.1|  PIN domain-containing protein f...  82.4    2e-14
gi|334319720|ref|YP_004556349.1|  PIN domain-containing protein f...  82.4    2e-14
gi|304413692|ref|ZP_07395136.1|  PIN domain-containing addiction ...  82.0    3e-14
gi|206601848|gb|EDZ38331.1|  Hypothetical protein CGL2_11278040 [...  82.0    3e-14
gi|330818818|ref|YP_004351035.1|  PilT domain-containing protein ...  80.9    6e-14
gi|87123102|ref|ZP_01078953.1|  hypothetical protein RS9917_04565...  79.0    2e-13
gi|15842022|ref|NP_337059.1|  hypothetical protein MT2569 [Mycoba...  73.9    7e-12
gi|317967919|ref|ZP_07969309.1|  hypothetical protein SCB02_00127...  73.9    8e-12
gi|15609631|ref|NP_217010.1|  hypothetical protein Rv2494 [Mycoba...  73.9    8e-12
gi|116624591|ref|YP_826747.1|  PilT domain-containing protein [Ca...  73.2    1e-11
gi|289758626|ref|ZP_06518004.1|  conserved hypothetical protein [...  73.2    1e-11
gi|254232624|ref|ZP_04925951.1|  conserved hypothetical protein [...  73.2    1e-11
gi|134291479|ref|YP_001115248.1|  PilT domain-containing protein ...  73.2    1e-11
gi|15610456|ref|NP_217837.1|  hypothetical protein Rv3320c [Mycob...  72.8    2e-11
gi|340628304|ref|YP_004746756.1|  hypothetical protein MCAN_33461...  72.8    2e-11
gi|289747139|ref|ZP_06506517.1|  conserved hypothetical protein [...  72.4    2e-11
gi|24214369|ref|NP_711850.1|  hypothetical protein LA_1669 [Lepto...  70.9    6e-11
gi|45657964|ref|YP_002050.1|  hypothetical protein LIC12116 [Lept...  70.1    9e-11
gi|340358885|ref|ZP_08681388.1|  PIN family toxin-antitoxin syste...  70.1    1e-10
gi|15609667|ref|NP_217046.1|  hypothetical protein Rv2530c [Mycob...  67.8    5e-10
gi|121595342|ref|YP_987238.1|  PilT domain-containing protein [Ac...  67.8    5e-10
gi|336115788|ref|YP_004570554.1|  hypothetical protein MLP_01370 ...  67.8    6e-10
gi|307701656|ref|ZP_07638672.1|  toxin-antitoxin system, toxin co...  67.0    1e-09
gi|269954934|ref|YP_003324723.1|  PIN domain-containing protein f...  66.2    1e-09
gi|336120816|ref|YP_004575602.1|  hypothetical protein MLP_51850 ...  66.2    2e-09
gi|87123276|ref|ZP_01079127.1|  hypothetical protein RS9917_05435...  66.2    2e-09
gi|256826277|ref|YP_003150237.1|  nucleic acid-binding protein [K...  63.5    9e-09
gi|320109069|ref|YP_004184659.1|  PIN domain-containing protein f...  63.5    9e-09
gi|262201135|ref|YP_003272343.1|  PIN domain-containing protein f...  62.0    3e-08
gi|114331350|ref|YP_747572.1|  PilT domain-containing protein [Ni...  62.0    3e-08
gi|326772971|ref|ZP_08232255.1|  toxin-antitoxin system, toxin co...  58.9    2e-07
gi|124515583|gb|EAY57093.1|  conserved hypothetical protein [Lept...  51.6    4e-05
gi|190895067|ref|YP_001985360.1|  hypothetical protein RHECIAT_PC...  49.7    2e-04
gi|333990807|ref|YP_004523421.1|  hypothetical protein JDM601_216...  48.5    3e-04
gi|16264146|ref|NP_436938.1|  hypothetical protein SM_b20412 [Sin...  48.1    4e-04
gi|218459869|ref|ZP_03499960.1|  hypothetical protein RetlK5_1036...  47.8    5e-04
gi|16264145|ref|NP_436937.1|  hypothetical protein SM_b20411 [Sin...  45.1    0.004
gi|218289454|ref|ZP_03493682.1|  PilT protein domain protein [Ali...  42.4    0.023


>gi|15607757|ref|NP_215131.1| hypothetical protein Rv0617 [Mycobacterium tuberculosis H37Rv]
 gi|15840020|ref|NP_335057.1| hypothetical protein MT0646 [Mycobacterium tuberculosis CDC1551]
 gi|31791800|ref|NP_854293.1| hypothetical protein Mb0634 [Mycobacterium bovis AF2122/97]
 79 more sequence titles
 Length=133

 Score =  262 bits (669),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 132/133 (99%), Positives = 133/133 (100%), Gaps = 0/133 (0%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAAR  60
            +TVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAAR
Sbjct  1    MTVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAAR  60

Query  61   DVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAH  120
            DVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAH
Sbjct  61   DVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAH  120

Query  121  LHGDVAVLIPTTT  133
            LHGDVAVLIPTTT
Sbjct  121  LHGDVAVLIPTTT  133


>gi|240169388|ref|ZP_04748047.1| hypothetical protein MkanA1_08748 [Mycobacterium kansasii ATCC 
12478]
Length=133

 Score =  211 bits (537),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 103/128 (81%), Positives = 113/128 (89%), Gaps = 0/128 (0%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARDVV  63
            LLD+NVLIALVVAEHVHHD AA WL A D GFATCP+TQGSLVRFL+R+GQ AA AR+VV
Sbjct  4    LLDSNVLIALVVAEHVHHDVAAAWLSARDNGFATCPITQGSLVRFLMRTGQPAAVAREVV  63

Query  64   SAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAHLHG  123
             AV+   RHEFWPD++SFA VE+ GVVGHRQVTDAYLAQLARS +GQLATLDSGLAHLH 
Sbjct  64   GAVETAKRHEFWPDSVSFADVEIGGVVGHRQVTDAYLAQLARSRNGQLATLDSGLAHLHS  123

Query  124  DVAVLIPT  131
            DVAVLIPT
Sbjct  124  DVAVLIPT  131


>gi|289749117|ref|ZP_06508495.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289689704|gb|EFD57133.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
Length=116

 Score =  190 bits (482),  Expect = 8e-47, Method: Compositional matrix adjust.
 Identities = 95/95 (100%), Positives = 95/95 (100%), Gaps = 0/95 (0%)

Query  39   PMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDA  98
            PMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDA
Sbjct  22   PMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDA  81

Query  99   YLAQLARSHDGQLATLDSGLAHLHGDVAVLIPTTT  133
            YLAQLARSHDGQLATLDSGLAHLHGDVAVLIPTTT
Sbjct  82   YLAQLARSHDGQLATLDSGLAHLHGDVAVLIPTTT  116


>gi|336179654|ref|YP_004585029.1| PIN domain-containing protein family protein [Frankia symbiont 
of Datisca glomerata]
 gi|334860634|gb|AEH11108.1| PIN domain protein family protein [Frankia symbiont of Datisca 
glomerata]
Length=131

 Score =  170 bits (431),  Expect = 5e-41, Method: Compositional matrix adjust.
 Identities = 81/128 (64%), Positives = 99/128 (78%), Gaps = 0/128 (0%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARDVV  63
            LLDANVLI L+V +HVHHDAA  WL  +   FATCP+T+GSLVR L+R GQSA  A  VV
Sbjct  4    LLDANVLITLIVTDHVHHDAAEAWLAGTAGRFATCPITEGSLVRLLIREGQSAQTATAVV  63

Query  64   SAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAHLHG  123
            SA+   SRHEFWPD +S++ V + GV+GHRQVTDAYLA LAR+H+G+LA+ + GLA LH 
Sbjct  64   SAIAGDSRHEFWPDEVSYSAVSMTGVIGHRQVTDAYLAYLARTHNGRLASFNQGLAKLHD  123

Query  124  DVAVLIPT  131
            D+  LIPT
Sbjct  124  DIVDLIPT  131


>gi|324997204|ref|ZP_08118316.1| toxin [Pseudonocardia sp. P1]
Length=141

 Score =  117 bits (294),  Expect = 4e-25, Method: Compositional matrix adjust.
 Identities = 67/130 (52%), Positives = 83/130 (64%), Gaps = 2/130 (1%)

Query  2    TVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARD  61
            T LLDANVLIAL V EH HHD A+ W  A    FA CP+ +G+LVRFLVR+G++ + A  
Sbjct  3    TYLLDANVLIALTVTEHEHHDRASAW-GARIERFALCPVVEGALVRFLVRAGETPSTATG  61

Query  62   VVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDG-QLATLDSGLAH  120
            ++ AV      EFWPD+LSFA   +  V GHRQVTDAYL  L  +  G   ATLD GLA 
Sbjct  62   LLRAVHALPGCEFWPDSLSFADARLGHVGGHRQVTDAYLTSLVAAVPGASPATLDEGLAR  121

Query  121  LHGDVAVLIP  130
               ++  L+P
Sbjct  122  DVPELTTLVP  131


>gi|227876599|ref|ZP_03994709.1| conserved hypothetical protein [Mobiluncus mulieris ATCC 35243]
 gi|227842800|gb|EEJ52999.1| conserved hypothetical protein [Mobiluncus mulieris ATCC 35243]
Length=130

 Score = 95.5 bits (236),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 51/128 (40%), Positives = 71/128 (56%), Gaps = 1/128 (0%)

Query  2    TVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARD  61
              L+DAN LIA  ++ H HHD    W   +DT   TCP+T+G+L RF++R+    + A  
Sbjct  3    NYLIDANALIAFNISTHQHHDVVLRWFAQADTVL-TCPITEGALFRFIIRNHFDFSVACQ  61

Query  62   VVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAHL  121
            +++      + +  PD L +      GV G RQVTD YLA+LA  HD  LAT D G+A L
Sbjct  62   LLTDFCAIPKVQRIPDDLHYDDANWTGVRGFRQVTDVYLAELALHHDALLATFDQGIAFL  121

Query  122  HGDVAVLI  129
              +   LI
Sbjct  122  RPEATFLI  129


>gi|225874392|ref|YP_002755851.1| Mycobacterium tuberculosis PIN domain protein [Acidobacterium 
capsulatum ATCC 51196]
 gi|225792658|gb|ACO32748.1| Mycobacterium tuberculosis PIN domain protein [Acidobacterium 
capsulatum ATCC 51196]
Length=146

 Score = 88.2 bits (217),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 55/130 (43%), Positives = 70/130 (54%), Gaps = 15/130 (11%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFLVRS--GQSAAAAR  60
            LLD NVL+A+    HVHH  A  W    S  G+ATCP+TQ   VR +      +SA  AR
Sbjct  5    LLDVNVLVAMFWPSHVHHVRAQQWFSEHSRHGWATCPLTQTGFVRIVSNPAFSKSAVTAR  64

Query  61   DVVSAVQCTSRHE---FWPDALSFAGVEVAG------VVGHRQVTDAYLAQLARSHDGQL  111
            D +  +Q   +H    FW D++   GV  A       ++GH+QVTDAYL  LA  H G+L
Sbjct  65   DAIHVLQENLKHRSHVFWADSV---GVNEAASFTHDRLIGHKQVTDAYLIGLAHHHQGRL  121

Query  112  ATLDSGLAHL  121
             T D GL  L
Sbjct  122  LTFDRGLGSL  131


>gi|294339103|emb|CAZ87457.1| conserved hypothetical protein; putative PIN domain [Thiomonas 
sp. 3As]
Length=143

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 49/126 (39%), Positives = 70/126 (56%), Gaps = 9/126 (7%)

Query  2    TVLLDANVLIALVVAEHVHHDAAADWLMASDTG-FATCPMTQGSLVRFL-----VRSGQS  55
            T LLD NVLIAL+   HV HDAA  W   + +  +ATCP+T+  L+R +       +  +
Sbjct  3    TFLLDVNVLIALIDPAHVQHDAAHHWFAETGSASWATCPLTENGLLRIVGHPRYPNTPGT  62

Query  56   AAAARDVVSAVQCTSRHEFWPDALSFAGVEVA---GVVGHRQVTDAYLAQLARSHDGQLA  112
             A    V+ A++    H FWPD +S    E+     ++ H Q+TD+YL  LAR H G+LA
Sbjct  63   PATVAVVLQALRALPGHHFWPDDISLLNPELILTDRLLSHTQITDSYLLALARHHSGKLA  122

Query  113  TLDSGL  118
            + D  L
Sbjct  123  SFDRKL  128


>gi|113953974|ref|YP_729372.1| hypothetical protein sync_0135 [Synechococcus sp. CC9311]
 gi|113881325|gb|ABI46283.1| Mycobacterium tuberculosis PIN domain family subfamily [Synechococcus 
sp. CC9311]
Length=148

 Score = 85.5 bits (210),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 52/125 (42%), Positives = 69/125 (56%), Gaps = 9/125 (7%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL--VRSGQSAAAAR  60
            LLD NVLIAL+  +HVHH+ +  W  A    G+ATCP+TQ +L+R L   R   S     
Sbjct  7    LLDVNVLIALIDPQHVHHEPSHRWFQAHGGDGWATCPLTQNALLRILGNPRYPNSPGGPA  66

Query  61   DVVSAVQ---CTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQLATL  114
             V+S +Q       H FWPDALS+      E   ++ H Q+TD YL  LA  H G+L + 
Sbjct  67   VVMSFLQELLAHPAHVFWPDALSWQATGVFEAEALLHHGQITDTYLLGLAVHHQGRLVSF  126

Query  115  DSGLA  119
            D  L+
Sbjct  127  DRRLS  131


>gi|241518561|ref|YP_002979189.1| PIN domain protein family protein [Rhizobium leguminosarum bv. 
trifolii WSM1325]
 gi|240862974|gb|ACS60638.1| PIN domain protein family protein [Rhizobium leguminosarum bv. 
trifolii WSM1325]
Length=147

 Score = 85.1 bits (209),  Expect = 3e-15, Method: Compositional matrix adjust.
 Identities = 49/128 (39%), Positives = 71/128 (56%), Gaps = 9/128 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL-----VRSGQ  54
            +T LLD NVLIAL+   HV HD A +W  A   + +ATCP+T+  ++R +       S  
Sbjct  1    MTFLLDVNVLIALIDPGHVAHDDAHEWFAAIGQSAWATCPITENGVIRIVGNPQYPNSPG  60

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQL  111
            S +   ++V  ++    H FWPD +S  G   +  A ++   QVTD YL  LA++  GQL
Sbjct  61   SPSLVMEIVRKLRSLPGHSFWPDDVSLVGSGDIAPAKILTSGQVTDTYLLALAKARGGQL  120

Query  112  ATLDSGLA  119
            AT D  L+
Sbjct  121  ATFDRKLS  128


>gi|333815879|gb|AEG08546.1| PIN domain protein family protein [Sinorhizobium meliloti BL225C]
Length=147

 Score = 84.3 bits (207),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 47/128 (37%), Positives = 72/128 (57%), Gaps = 9/128 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL-----VRSGQ  54
            +T LLD NVLIAL+   H+ HD A +W  +   T +ATCP+T+  ++R +       S  
Sbjct  1    MTFLLDVNVLIALIDPSHIGHDDAHEWFASIGQTAWATCPITENGVIRIVGNPEYPNSPG  60

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQL  111
            S   A ++V+ ++    H FWPD +S  G   +  + ++   QVTD YL  LA++  G+L
Sbjct  61   SPLPAMEIVAKLRSLPGHVFWPDDVSLVGSSDIIPSKILTSGQVTDTYLLALAKARGGKL  120

Query  112  ATLDSGLA  119
            AT D  L+
Sbjct  121  ATFDRKLS  128


>gi|254420497|ref|ZP_05034221.1| Mycobacterium tuberculosis PIN domain family [Brevundimonas sp. 
BAL3]
 gi|196186674|gb|EDX81650.1| Mycobacterium tuberculosis PIN domain family [Brevundimonas sp. 
BAL3]
Length=145

 Score = 83.6 bits (205),  Expect = 9e-15, Method: Compositional matrix adjust.
 Identities = 53/129 (42%), Positives = 72/129 (56%), Gaps = 11/129 (8%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMASDTG-FATCPMTQGSLVRFLVRS------G  53
            +T LLD NVLIALV   HV HD A  W      G +ATCP+T+  LVR +  S      G
Sbjct  1    MTYLLDVNVLIALVDPRHVFHDTANGWFQREAAGSWATCPITENGLVRIVGNSRYRNPVG  60

Query  54   QSAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQ  110
              +   R ++  ++  + H FWPDA+S A     + + +    Q+TDAYL  LA S+ G+
Sbjct  61   PPSEIVR-ILELLRDMAGHVFWPDAISLADDRLFDPSALTTPEQITDAYLLALAVSNGGR  119

Query  111  LATLDSGLA  119
            LATLD  L+
Sbjct  120  LATLDRRLS  128


>gi|344199817|ref|YP_004784143.1| PIN domain-containing protein family protein [Acidithiobacillus 
ferrivorans SS3]
 gi|343775261|gb|AEM47817.1| PIN domain protein family protein [Acidithiobacillus ferrivorans 
SS3]
Length=142

 Score = 82.4 bits (202),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 48/127 (38%), Positives = 72/127 (57%), Gaps = 9/127 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL-----VRSGQ  54
            +T LLD NVLIAL+   HV HD A +W  A     +ATCP+T+  ++R +       S  
Sbjct  1    MTFLLDVNVLIALIDPMHVQHDMAHEWFAAHGQPAWATCPLTENGVLRIVGHPRYPNSPG  60

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAGV---EVAGVVGHRQVTDAYLAQLARSHDGQL  111
            + AA   ++  ++ +  H FWPD +S   V   + + ++   Q+TD+YL  LA +H+GQL
Sbjct  61   TPAAVAPLIQGLRASPGHVFWPDDISLLDVDHIDASRLLTSGQITDSYLLALACAHEGQL  120

Query  112  ATLDSGL  118
            AT D  L
Sbjct  121  ATFDHRL  127


>gi|334319720|ref|YP_004556349.1| PIN domain-containing protein family protein [Sinorhizobium meliloti 
AK83]
 gi|334097459|gb|AEG55469.1| PIN domain protein family protein [Sinorhizobium meliloti AK83]
Length=147

 Score = 82.4 bits (202),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 46/128 (36%), Positives = 71/128 (56%), Gaps = 9/128 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL-----VRSGQ  54
            +T LLD NVLIAL+   H+ HD A +W  +   T +ATCP+T+  ++R +       S  
Sbjct  1    MTFLLDVNVLIALIDPSHIGHDDAHEWFASIGQTTWATCPITENGVIRIVGNPEYPNSPG  60

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQL  111
            S     ++V+ ++    H FWPD +S  G   +  + ++   QVTD YL  LA++  G+L
Sbjct  61   SPLPVMEIVAKLRSLPGHVFWPDDVSLVGSSDIIPSKILTSGQVTDTYLLALAKARGGKL  120

Query  112  ATLDSGLA  119
            AT D  L+
Sbjct  121  ATFDRKLS  128


>gi|304413692|ref|ZP_07395136.1| PIN domain-containing addiction module [Candidatus Regiella insecticola 
LSR1]
 gi|304283783|gb|EFL92177.1| PIN domain-containing addiction module [Candidatus Regiella insecticola 
LSR1]
Length=147

 Score = 82.0 bits (201),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 54/142 (39%), Positives = 73/142 (52%), Gaps = 12/142 (8%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFL-----VRSGQSAAA  58
            LLD NVLIALV   H+ HDAA  W       +ATCP+TQ  ++R +       S  + AA
Sbjct  4    LLDVNVLIALVDPAHIQHDAAHTWFEKQGQDWATCPLTQNGVLRIVGHGRYPNSPGTPAA  63

Query  59   ARDVVSAVQCTSRHEFWPDALSFAGVE---VAGVVGHRQVTDAYLAQLARSHDGQLATLD  115
              ++++ +     H FWPD +S    E      ++   Q+TD+YL  LA +H+GQLAT D
Sbjct  64   VAELMTTLCSLPGHCFWPDDISLLDTEKLDATRLLTSAQLTDSYLLALACAHNGQLATFD  123

Query  116  SGLA----HLHGDVAVLIPTTT  133
              L     H       LIP TT
Sbjct  124  RRLETDAVHNGARSLHLIPATT  145


>gi|206601848|gb|EDZ38331.1| Hypothetical protein CGL2_11278040 [Leptospirillum sp. Group 
II '5-way CG']
Length=142

 Score = 82.0 bits (201),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 51/124 (42%), Positives = 72/124 (59%), Gaps = 10/124 (8%)

Query  4    LLDANVLIALVVAEHVHHDAAADW--LMASDTGFATCPMTQGSLVRFLVRSGQ----SAA  57
            LLD NVLIAL+ ++HV H  A +W  L A+D G+A+CP+TQ   +R +         S +
Sbjct  4    LLDINVLIALLDSDHVSHHTAREWFSLHATD-GWASCPLTQNGCMRIMSHPNYPNPISIS  62

Query  58   AARDVVSAVQCTSRHEFWPDALSF--AGV-EVAGVVGHRQVTDAYLAQLARSHDGQLATL  114
              R+ +S    +S H+FWPD +SF  AGV + A + G  Q+TD YL  LA  H G+  T 
Sbjct  63   RIRERLSEAASSSLHQFWPDDVSFLDAGVADTARIHGPHQITDLYLLALAIRHKGRFVTF  122

Query  115  DSGL  118
            D  +
Sbjct  123  DGSI  126


>gi|330818818|ref|YP_004351035.1| PilT domain-containing protein [Burkholderia gladioli BSR3]
 gi|327374360|gb|AEA65712.1| PilT domain-containing protein [Burkholderia gladioli BSR3]
Length=151

 Score = 80.9 bits (198),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 51/127 (41%), Positives = 73/127 (58%), Gaps = 9/127 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFL-----VRSGQ  54
            +T LLD NVLIAL+ A HV H+AA +W   A+   +ATCP+T+  ++R +       +  
Sbjct  9    MTYLLDVNVLIALLDAGHVQHEAAHEWFGSAAHAAWATCPLTENGVLRIIGNPRYPNTLG  68

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQL  111
            + AA   +V+ ++    H FW D LS      V+V+ ++   QVTD YL  LAR H G+L
Sbjct  69   TPAAVAPLVTQLRAHPGHTFWWDDLSLLNPEQVDVSRILATDQVTDTYLLALARVHGGKL  128

Query  112  ATLDSGL  118
            AT D  L
Sbjct  129  ATFDRRL  135


>gi|87123102|ref|ZP_01078953.1| hypothetical protein RS9917_04565 [Synechococcus sp. RS9917]
 gi|86168822|gb|EAQ70078.1| hypothetical protein RS9917_04565 [Synechococcus sp. RS9917]
Length=149

 Score = 79.0 bits (193),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 49/125 (40%), Positives = 70/125 (56%), Gaps = 9/125 (7%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVRFL--VRSGQSAAAAR  60
            LLD NVLIAL+  +HVHH+ A  W  A+ + G+ATCP+TQ +L+R L   R   S     
Sbjct  7    LLDVNVLIALLDPQHVHHEPAHRWFQANASYGWATCPLTQNALLRILSNPRYPNSPGGPA  66

Query  61   DVVSAVQCTSRHE---FWPDALSFA---GVEVAGVVGHRQVTDAYLAQLARSHDGQLATL  114
             V+  +Q    H    FWPD LS++    ++   ++ H Q+TD YL  LA    G L + 
Sbjct  67   SVMPLLQGMLSHPGHLFWPDLLSWSTDGELQAELLLHHGQITDTYLLALAVHQGGCLMSF  126

Query  115  DSGLA  119
            D+ L+
Sbjct  127  DARLS  131


>gi|15842022|ref|NP_337059.1| hypothetical protein MT2569 [Mycobacterium tuberculosis CDC1551]
 gi|254366798|ref|ZP_04982840.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|13882299|gb|AAK46873.1| hypothetical protein MT2569 [Mycobacterium tuberculosis CDC1551]
 gi|134152308|gb|EBA44353.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|323718902|gb|EGB28056.1| toxin protein [Mycobacterium tuberculosis CDC1551A]
Length=141

 Score = 73.9 bits (180),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 48/121 (40%), Positives = 68/121 (57%), Gaps = 6/121 (4%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVRF-----LVRSGQSAA  57
            LLD N L+AL    H+HH    +W  A+ T G+ATCP+T+   VR      ++ S    A
Sbjct  3    LLDVNALVALAWDSHIHHARIREWFTANATLGWATCPLTEAGFVRVSTNPKVLPSAIGIA  62

Query  58   AARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
             AR V+ A++    H F  D +S    +V  +VG+RQVTDA+L  LAR    +L T D+G
Sbjct  63   DARPVLVALRAVGGHRFLADDVSLVDDDVPLIVGYRQVTDAHLLTLARRRGVRLVTFDAG  122

Query  118  L  118
            +
Sbjct  123  V  123


>gi|317967919|ref|ZP_07969309.1| hypothetical protein SCB02_00127 [Synechococcus sp. CB0205]
Length=144

 Score = 73.9 bits (180),  Expect = 8e-12, Method: Compositional matrix adjust.
 Identities = 50/127 (40%), Positives = 67/127 (53%), Gaps = 15/127 (11%)

Query  2    TVLLDANVLIALVVAEHVHHDAAADWLMASDTG---FATCPMTQGSLVRFL------VRS  52
            T LLD NVLIAL+   HVHH+    W   +D G   +A+C MTQ +++R L      +  
Sbjct  5    TALLDVNVLIALLDPHHVHHELCHGWF--ADRGAAPWASCAMTQNAVLRILGNPRYPISP  62

Query  53   GQSAAAARDVVSAVQCTSRHEFW---PDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDG  109
            G     A  + S V+    HEFW   P  LS   +  + ++ + Q+TD YL  LAR H G
Sbjct  63   GPPPTIAPHLDSLVEHPG-HEFWDSNPSLLSQGFIARSALIDYAQITDLYLLALARHHGG  121

Query  110  QLATLDS  116
             LATLD 
Sbjct  122  TLATLDK  128


>gi|15609631|ref|NP_217010.1| hypothetical protein Rv2494 [Mycobacterium tuberculosis H37Rv]
 gi|31793674|ref|NP_856167.1| hypothetical protein Mb2522 [Mycobacterium bovis AF2122/97]
 gi|121638376|ref|YP_978600.1| hypothetical protein BCG_2514 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 68 more sequence titles
 Length=141

 Score = 73.9 bits (180),  Expect = 8e-12, Method: Compositional matrix adjust.
 Identities = 48/121 (40%), Positives = 68/121 (57%), Gaps = 6/121 (4%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVRF-----LVRSGQSAA  57
            LLD N L+AL    H+HH    +W  A+ T G+ATCP+T+   VR      ++ S    A
Sbjct  3    LLDVNALVALAWDSHIHHARIREWFTANATLGWATCPLTEAGFVRVSTNPKVLPSAIGIA  62

Query  58   AARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
             AR V+ A++    H F  D +S    +V  +VG+RQVTDA+L  LAR    +L T D+G
Sbjct  63   DARRVLVALRAVGGHRFLADDVSLVDDDVPLIVGYRQVTDAHLLTLARRRGVRLVTFDAG  122

Query  118  L  118
            +
Sbjct  123  V  123


>gi|116624591|ref|YP_826747.1| PilT domain-containing protein [Candidatus Solibacter usitatus 
Ellin6076]
 gi|116227753|gb|ABJ86462.1| PIN domain family protein [Candidatus Solibacter usitatus Ellin6076]
Length=147

 Score = 73.2 bits (178),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 47/128 (37%), Positives = 62/128 (49%), Gaps = 17/128 (13%)

Query  4    LLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFLVRSGQSAAAARDV  62
            LLD NVLIAL    H+ H  A  W  +    G+ATCP+T    VR L   G     A   
Sbjct  5    LLDVNVLIALFDPAHIDHVEAHRWFGLNRKRGWATCPITINGCVRILSSPGYPGINA---  61

Query  63   VSAVQCTSR---------HEFWPDALSF---AGVEVAGVVGHRQVTDAYLAQLARSHDGQ  110
             S  + T+R         H FWPD++S    A    + + GH+ +TD YL  LA  + G+
Sbjct  62   -SPAEITARMQASFANVDHHFWPDSVSLLDEALFRPSMITGHKNITDVYLLGLAVRNHGR  120

Query  111  LATLDSGL  118
            LAT D  +
Sbjct  121  LATFDQSI  128


>gi|289758626|ref|ZP_06518004.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|294994398|ref|ZP_06800089.1| toxin [Mycobacterium tuberculosis 210]
 gi|289714190|gb|EFD78202.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|326904108|gb|EGE51041.1| toxin [Mycobacterium tuberculosis W-148]
 gi|339295377|gb|AEJ47488.1| hypothetical protein CCDC5079_2298 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339298997|gb|AEJ51107.1| hypothetical protein CCDC5180_2270 [Mycobacterium tuberculosis 
CCDC5180]
Length=141

 Score = 73.2 bits (178),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 48/121 (40%), Positives = 68/121 (57%), Gaps = 6/121 (4%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVR-----FLVRSGQSAA  57
            LLD N L+AL    H+HH    +W  A+ T G+ATCP+T+   VR      ++ S    A
Sbjct  3    LLDVNALVALAWDSHIHHARIREWFTANATLGWATCPLTEAGFVRASTNPKVLPSAIGIA  62

Query  58   AARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
             AR V+ A++    H F  D +S    +V  +VG+RQVTDA+L  LAR    +L T D+G
Sbjct  63   DARRVLVALRAVGGHRFLADDVSLVDDDVPLIVGYRQVTDAHLLTLARRRGVRLVTFDAG  122

Query  118  L  118
            +
Sbjct  123  V  123


>gi|254232624|ref|ZP_04925951.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 gi|124601683|gb|EAY60693.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
Length=141

 Score = 73.2 bits (178),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 47/121 (39%), Positives = 68/121 (57%), Gaps = 6/121 (4%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVRF-----LVRSGQSAA  57
            L+D N L+AL    H+HH    +W  A+ T G+ATCP+T+   VR      ++ S    A
Sbjct  3    LIDVNALVALAWDSHIHHARIREWFTANATLGWATCPLTEAGFVRVSTNPKVLPSAIGIA  62

Query  58   AARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
             AR V+ A++    H F  D +S    +V  +VG+RQVTDA+L  LAR    +L T D+G
Sbjct  63   DARPVLVALRAVGGHRFLADDVSLVDDDVPLIVGYRQVTDAHLLTLARRRGVRLVTFDAG  122

Query  118  L  118
            +
Sbjct  123  V  123


>gi|134291479|ref|YP_001115248.1| PilT domain-containing protein [Burkholderia vietnamiensis G4]
 gi|134134668|gb|ABO58993.1| PIN domain family protein [Burkholderia vietnamiensis G4]
Length=144

 Score = 73.2 bits (178),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 45/127 (36%), Positives = 67/127 (53%), Gaps = 9/127 (7%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFLVRSGQ-----  54
            +T LLD NVLIAL+   HV H+ A  W      + +ATCP+T+  ++R +          
Sbjct  2    ITYLLDVNVLIALLDPAHVQHEPAHAWFGRVGHSAWATCPLTENGVLRIIGNPKYPNTMV  61

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSF---AGVEVAGVVGHRQVTDAYLAQLARSHDGQL  111
            S A+   +V  ++  + H FW D +S      V+   ++   Q+TD YL  LAR+H G+L
Sbjct  62   SPASVAPLVVQLRSHAGHTFWSDDVSLLDEKHVDATRLLSSAQLTDTYLLALARAHKGKL  121

Query  112  ATLDSGL  118
            AT D  L
Sbjct  122  ATFDRRL  128


>gi|15610456|ref|NP_217837.1| hypothetical protein Rv3320c [Mycobacterium tuberculosis H37Rv]
 gi|15842912|ref|NP_337949.1| hypothetical protein MT3421 [Mycobacterium tuberculosis CDC1551]
 gi|31794501|ref|NP_856994.1| hypothetical protein Mb3349c [Mycobacterium bovis AF2122/97]
 77 more sequence titles
 Length=142

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 47/124 (38%), Positives = 69/124 (56%), Gaps = 8/124 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMAS-DTGFATCPMTQGSLVRFLVR----SGQSAAA  58
            LLD NVL+AL+  +HV H+ A  W+    + G+A+C +TQ   VR + +    S  S A 
Sbjct  4    LLDVNVLLALLDRDHVDHERARAWITGQIERGWASCAITQNGFVRVISQPRYPSPISVAH  63

Query  59   ARDVVSAVQCTSRHEFWPDALSFAGVEV---AGVVGHRQVTDAYLAQLARSHDGQLATLD  115
            A D+++    T  HEFW   +S    +V   + +   +QVTDAYL  LA +HDG+  T D
Sbjct  64   AIDLLARATHTRYHEFWSCTVSILDSKVIDRSRLHSPKQVTDAYLLALAVAHDGRFVTFD  123

Query  116  SGLA  119
              +A
Sbjct  124  QSIA  127


>gi|340628304|ref|YP_004746756.1| hypothetical protein MCAN_33461 [Mycobacterium canettii CIPT 
140010059]
 gi|340006494|emb|CCC45677.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=142

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 47/124 (38%), Positives = 69/124 (56%), Gaps = 8/124 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMAS-DTGFATCPMTQGSLVRFLVR----SGQSAAA  58
            LLD NVL+AL+  +HV H+ A  W+    + G+A+C +TQ   VR + +    S  S A 
Sbjct  4    LLDVNVLLALLDRDHVDHERARAWITGQIERGWASCAITQNGFVRVISQPRYPSPISVAH  63

Query  59   ARDVVSAVQCTSRHEFWPDALSFAGVEV---AGVVGHRQVTDAYLAQLARSHDGQLATLD  115
            A D+++    T  HEFW   +S    +V   + +   +QVTDAYL  LA +HDG+  T D
Sbjct  64   AIDLLARATHTRYHEFWSCTVSILDSKVIDRSRLHSPKQVTDAYLLALAVAHDGRFVTFD  123

Query  116  SGLA  119
              +A
Sbjct  124  QAIA  127


>gi|289747139|ref|ZP_06506517.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289687667|gb|EFD55155.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
Length=202

 Score = 72.4 bits (176),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 47/124 (38%), Positives = 69/124 (56%), Gaps = 8/124 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMAS-DTGFATCPMTQGSLVRFLVR----SGQSAAA  58
            LLD NVL+AL+  +HV H+ A  W+    + G+A+C +TQ   VR + +    S  S A 
Sbjct  4    LLDVNVLLALLDRDHVDHERARAWITGQIERGWASCAITQNGFVRVISQPRYPSPISVAH  63

Query  59   ARDVVSAVQCTSRHEFWPDALSFAGVEV---AGVVGHRQVTDAYLAQLARSHDGQLATLD  115
            A D+++    T  HEFW   +S    +V   + +   +QVTDAYL  LA +HDG+  T D
Sbjct  64   AIDLLARATHTRYHEFWSCTVSILDSKVIDRSRLHSPKQVTDAYLLALAVAHDGRFVTFD  123

Query  116  SGLA  119
              +A
Sbjct  124  QSIA  127


>gi|24214369|ref|NP_711850.1| hypothetical protein LA_1669 [Leptospira interrogans serovar 
Lai str. 56601]
 gi|24195304|gb|AAN48868.1| hypothetical protein LA_1669 [Leptospira interrogans serovar 
Lai str. 56601]
Length=144

 Score = 70.9 bits (172),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 45/130 (35%), Positives = 67/130 (52%), Gaps = 11/130 (8%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFLVRSGQSA-AA  58
            +  LLD NVLI+L  + HV H+ A  W    +  G+ATCP+TQ +LVR +  S       
Sbjct  1    MKYLLDVNVLISLCDSNHVFHEKAWKWFDRKAKNGWATCPITQNALVRIMSHSSYPGNPG  60

Query  59   ARDVVSAVQCT----SRHEFWPDALSFAG----VEVAGVVGHRQVTDAYLAQLARSHDGQ  110
              +VVSA+  +      H+F PD +S       + +   V  +Q+TD YL  L+  H  +
Sbjct  61   GVEVVSAILHSLLKVKGHQFIPDNISINSSLFYLNIVS-VSSKQITDVYLLALSVHHKVK  119

Query  111  LATLDSGLAH  120
             AT DS + +
Sbjct  120  FATFDSKIPY  129


>gi|45657964|ref|YP_002050.1| hypothetical protein LIC12116 [Leptospira interrogans serovar 
Copenhageni str. Fiocruz L1-130]
 gi|45601205|gb|AAS70687.1| conserved hypothetical protein [Leptospira interrogans serovar 
Copenhageni str. Fiocruz L1-130]
Length=144

 Score = 70.1 bits (170),  Expect = 9e-11, Method: Compositional matrix adjust.
 Identities = 45/130 (35%), Positives = 67/130 (52%), Gaps = 11/130 (8%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFLVRSGQSA-AA  58
            +  LLD NVLI+L  + HV H+ A  W    +  G+ATCP+TQ +LVR +  S       
Sbjct  1    MKYLLDVNVLISLCDSNHVFHEKAWKWFDRKARNGWATCPITQNALVRIMSHSSYPGNPG  60

Query  59   ARDVVSAVQCT----SRHEFWPDALSFAG----VEVAGVVGHRQVTDAYLAQLARSHDGQ  110
              +VVSA+  +      H+F PD +S       + +   V  +Q+TD YL  L+  H  +
Sbjct  61   GVEVVSAILHSLLKVKGHQFIPDNISINSSLFYLNIVS-VSSKQITDVYLLALSVHHKVK  119

Query  111  LATLDSGLAH  120
             AT DS + +
Sbjct  120  FATFDSKIPY  129


>gi|340358885|ref|ZP_08681388.1| PIN family toxin-antitoxin system [Actinomyces sp. oral taxon 
448 str. F0400]
 gi|339885631|gb|EGQ75340.1| PIN family toxin-antitoxin system [Actinomyces sp. oral taxon 
448 str. F0400]
Length=148

 Score = 70.1 bits (170),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 50/139 (36%), Positives = 71/139 (52%), Gaps = 14/139 (10%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTG-FATCPMTQGSLVRFLVRSGQSA-----A  57
            LLD NV++AL +A H HH  A  W    D G +ATCP+T+ +  R L+ S  +      +
Sbjct  10   LLDVNVMLALSLANHAHHRVATSWF--EDVGAWATCPITESAYCRLLLNSHVTGFELGVS  67

Query  58   AARDVVSAVQCTSRHEFWPDA--LSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLD  115
               D +      S HE   D+  L+   ++V+G+VG RQ+TD +L  LA      LATLD
Sbjct  68   EVFDALRTFCSVSGHELIEDSASLTAPAIDVSGLVGRRQITDFHLVDLAARSGALLATLD  127

Query  116  S----GLAHLHGDVAVLIP  130
            +     LAH       +IP
Sbjct  128  ARIPPALAHEDRRFVEVIP  146


>gi|15609667|ref|NP_217046.1| hypothetical protein Rv2530c [Mycobacterium tuberculosis H37Rv]
 gi|15842064|ref|NP_337101.1| hypothetical protein MT2605 [Mycobacterium tuberculosis CDC1551]
 gi|31793711|ref|NP_856204.1| hypothetical protein Mb2559c [Mycobacterium bovis AF2122/97]
 81 more sequence titles
 Length=139

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 48/124 (39%), Positives = 65/124 (53%), Gaps = 11/124 (8%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRF-----LVRSGQ  54
            +T LLD NVLIAL    HVHH AA  W    S  G+AT P+T+   VR      +++   
Sbjct  1    MTALLDVNVLIALGWPNHVHHAAAQRWFTQFSSNGWATTPITEAGYVRISSNRSVMQVST  60

Query  55   SAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAG----VVGHRQVTDAYLAQLARSHDGQ  110
            + A A   ++A+   + H FWPD +    V  AG    V  HR+VTD +L  LA  + G+
Sbjct  61   TPAIAIAQLAAMTSLAGHTFWPDDVPLI-VGSAGDRDAVSNHRRVTDCHLIALAARYGGR  119

Query  111  LATL  114
            L T 
Sbjct  120  LVTF  123


>gi|121595342|ref|YP_987238.1| PilT domain-containing protein [Acidovorax sp. JS42]
 gi|120607422|gb|ABM43162.1| PIN domain family protein [Acidovorax sp. JS42]
Length=142

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 45/124 (37%), Positives = 62/124 (50%), Gaps = 8/124 (6%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMAS-DTGFATCPMTQGSLVRFLVRSGQSA---  56
            +  LLD NVLIAL+ A H+HH  A+ WL  S   G+A+CP+TQ   +R + +        
Sbjct  1    MRALLDVNVLIALLDAAHIHHQRASQWLEQSLHHGWASCPLTQNGCLRIMAQPAYPQALP  60

Query  57   -AAARDVVSAVQCTSRHEFWPDALSFA---GVEVAGVVGHRQVTDAYLAQLARSHDGQLA  112
             AA    +     T  H F  D  S      +    ++GHRQVTDAYL  LA  H  +  
Sbjct  61   LAAVAQRLGQAAATPAHLFIADDYSLLDADSLHWPQLLGHRQVTDAYLLGLAVRHGCRFV  120

Query  113  TLDS  116
            + D+
Sbjct  121  SFDA  124


>gi|336115788|ref|YP_004570554.1| hypothetical protein MLP_01370 [Microlunatus phosphovorus NM-1]
 gi|334683566|dbj|BAK33151.1| hypothetical protein MLP_01370 [Microlunatus phosphovorus NM-1]
Length=139

 Score = 67.8 bits (164),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 48/123 (40%), Positives = 70/123 (57%), Gaps = 8/123 (6%)

Query  3    VLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRS---GQS--AA  57
            +LLD NVL+AL   +HVHH+ A       DT + TCP T+  LVR L+     G+    +
Sbjct  1    MLLDVNVLLALSWDQHVHHEIAHQRFAELDT-WNTCPTTEAGLVRLLLTEQVVGRKVIGS  59

Query  58   AARDVVSAVQCTSRHEFWPDALSFAG--VEVAGVVGHRQVTDAYLAQLARSHDGQLATLD  115
             A   ++A++  S   F PD+ S A   ++   ++G RQVTD  L  LA S++ +LAT D
Sbjct  60   EALGQLAAMRGVSGWGFLPDSGSLAEPVIDTRVLMGRRQVTDLQLVNLAASNNTKLATFD  119

Query  116  SGL  118
            +GL
Sbjct  120  AGL  122


>gi|307701656|ref|ZP_07638672.1| toxin-antitoxin system, toxin component, PIN family [Mobiluncus 
mulieris FB024-16]
 gi|307613159|gb|EFN92412.1| toxin-antitoxin system, toxin component, PIN family [Mobiluncus 
mulieris FB024-16]
Length=96

 Score = 67.0 bits (162),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 35/92 (39%), Positives = 50/92 (55%), Gaps = 0/92 (0%)

Query  38   CPMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTD  97
            CP+ +G+L RF+VR+      A  +++      +    PD L +   +  GV GHRQ+TD
Sbjct  4    CPIAEGALFRFVVRNHFGFPVAHQLLADFCDIPKVLRIPDDLHYDNADWTGVRGHRQITD  63

Query  98   AYLAQLARSHDGQLATLDSGLAHLHGDVAVLI  129
             YL +LA+ H   LAT D G+A L  D   LI
Sbjct  64   VYLVELAQRHRALLATFDQGIAALRPDATFLI  95


>gi|269954934|ref|YP_003324723.1| PIN domain-containing protein family protein [Xylanimonas cellulosilytica 
DSM 15894]
 gi|269303615|gb|ACZ29165.1| PIN domain protein family protein [Xylanimonas cellulosilytica 
DSM 15894]
Length=141

 Score = 66.2 bits (160),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 49/125 (40%), Positives = 60/125 (48%), Gaps = 8/125 (6%)

Query  2    TVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRF-----LVRSGQSA  56
            T L D NVLIAL   +HVHH  A  WL      FAT  +T+   VR      +V    S 
Sbjct  3    TDLPDVNVLIALHFEDHVHHVPAMSWLRKGGQ-FATTALTEAGFVRVSMNPAIVGEPFSG  61

Query  57   AAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVV--GHRQVTDAYLAQLARSHDGQLATL  114
              A + +  ++  +R  FW D  S A    A  V  GH+Q TD +L  LA S DG L T 
Sbjct  62   VEALEALRRLRGHTRATFWADDTSLATSPFADRVLSGHKQTTDLHLLNLAASRDGVLVTF  121

Query  115  DSGLA  119
            DS L 
Sbjct  122  DSKLG  126


>gi|336120816|ref|YP_004575602.1| hypothetical protein MLP_51850 [Microlunatus phosphovorus NM-1]
 gi|334688614|dbj|BAK38199.1| hypothetical protein MLP_51850 [Microlunatus phosphovorus NM-1]
Length=148

 Score = 66.2 bits (160),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 44/123 (36%), Positives = 67/123 (55%), Gaps = 8/123 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVR---SGQ--SAAA  58
            L D N+L+AL+   HVHH  A  W  + +  FAT P+T+   +R  +    +GQ  S   
Sbjct  13   LPDVNLLVALLHPAHVHHLQAQAWFTSVER-FATTPITESGFIRMALNPAVAGQVTSLDD  71

Query  59   ARDVVSAVQCTSRHEFWPD--ALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDS  116
            A   +++V+   R E+  D  +L+   +++ G+VG RQVTD +L  LA  H  +L T D 
Sbjct  72   AMSSLNSVRADKRVEYVADDTSLALPTIDLVGLVGFRQVTDFHLVNLAACHSARLVTFDR  131

Query  117  GLA  119
             LA
Sbjct  132  KLA  134


>gi|87123276|ref|ZP_01079127.1| hypothetical protein RS9917_05435 [Synechococcus sp. RS9917]
 gi|86168996|gb|EAQ70252.1| hypothetical protein RS9917_05435 [Synechococcus sp. RS9917]
Length=143

 Score = 66.2 bits (160),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 42/125 (34%), Positives = 69/125 (56%), Gaps = 8/125 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFLVR----SGQSAAA  58
            LLD NV+IAL+  +H  H  A+ WL   +  G+A+CP++Q  ++R + +    + Q  AA
Sbjct  4    LLDINVIIALLDGQHSLHSTASQWLSHHAAAGWASCPISQNGVIRIMSQPSYPNAQPPAA  63

Query  59   ARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQLATLD  115
                ++       H+FW  ALS      ++   ++G RQ+TDAYL  +A ++DG L + D
Sbjct  64   IASRLAEACRHPSHQFWGGALSLLDPRHLKWHCLLGPRQITDAYLLAVAVANDGCLVSFD  123

Query  116  SGLAH  120
              + H
Sbjct  124  RRIHH  128


>gi|256826277|ref|YP_003150237.1| nucleic acid-binding protein [Kytococcus sedentarius DSM 20547]
 gi|256689670|gb|ACV07472.1| predicted nucleic acid-binding protein, contains PIN domain [Kytococcus 
sedentarius DSM 20547]
Length=147

 Score = 63.5 bits (153),  Expect = 9e-09, Method: Compositional matrix adjust.
 Identities = 48/130 (37%), Positives = 64/130 (50%), Gaps = 9/130 (6%)

Query  1    VTVLLDANVLIALVVAEHVHHDAAADWLMAS-DTGFATCPMTQGSLVRFLVRSGQSAA--  57
            V  LLD N LIAL+  +H  H+AA  W       G+ATC  TQ   +R + + G  +   
Sbjct  7    VAALLDVNTLIALLDIDHRDHEAAHRWAEERLSNGWATCATTQMGFLRVISQPGYPSPIT  66

Query  58   ---AARDVVSAVQCTSRHEFWP-DALSFAG-VEVAGVVGHRQVTDAYLAQLARSHDGQLA  112
               A R +  A    S HE+W  +    AG V +  + GHRQ+TDAYL  LA   +G L 
Sbjct  67   VDEAGRLLRRATDHPS-HEYWSSEPQPCAGSVSLDVITGHRQITDAYLLALAVHQNGCLV  125

Query  113  TLDSGLAHLH  122
            T D  +   H
Sbjct  126  TFDRRITTRH  135


>gi|320109069|ref|YP_004184659.1| PIN domain-containing protein family protein [Terriglobus saanensis 
SP1PR4]
 gi|319927590|gb|ADV84665.1| PIN domain protein family protein [Terriglobus saanensis SP1PR4]
Length=147

 Score = 63.5 bits (153),  Expect = 9e-09, Method: Compositional matrix adjust.
 Identities = 42/127 (34%), Positives = 59/127 (47%), Gaps = 6/127 (4%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLV--RSGQ-SAAAAR  60
            LLD NV +AL+  +H HH     W       +A CP T+   +R     R GQ +   A 
Sbjct  9    LLDVNVFVALLSEDHTHHQLVTAWFNTPSLLWAICPFTEAGFLRNATAPRPGQITMTEAT  68

Query  61   DVVSAVQCTSRHEFWP---DALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
             V++ +     + + P   D  S        + G +QVTDAYL  LA   D  L T+D G
Sbjct  69   AVLARMAQVPGYHYLPITADWRSLCSPFSTRLYGTKQVTDAYLLGLAVREDLVLVTMDKG  128

Query  118  LAHLHGD  124
            + HL G+
Sbjct  129  ILHLAGN  135


>gi|262201135|ref|YP_003272343.1| PIN domain-containing protein family protein [Gordonia bronchialis 
DSM 43247]
 gi|262084482|gb|ACY20450.1| PIN domain protein family protein [Gordonia bronchialis DSM 43247]
Length=144

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 45/123 (37%), Positives = 69/123 (57%), Gaps = 8/123 (6%)

Query  3    VLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQ-----SAA  57
            +LLD NVL+AL   +HVHH  A +   A  T ++TCP+T+  LVR L+         + A
Sbjct  6    MLLDINVLVALSWDQHVHHGVAHE-RFAQLTEWSTCPVTEAGLVRVLMTESAVGRVVTGA  64

Query  58   AARDVVSAVQCTSRHEFWPDALSFAG--VEVAGVVGHRQVTDAYLAQLARSHDGQLATLD  115
             A   ++A++  +   F  D  S A   +++  ++G RQVTD +L  LA  +  +LAT D
Sbjct  65   EALGQLAALRTVTGWGFLHDDASLADSVIDLRVLMGRRQVTDLHLVNLAARNGRKLATFD  124

Query  116  SGL  118
            +GL
Sbjct  125  AGL  127


>gi|114331350|ref|YP_747572.1| PilT domain-containing protein [Nitrosomonas eutropha C91]
 gi|114308364|gb|ABI59607.1| PIN domain family protein [Nitrosomonas eutropha C91]
Length=142

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 45/124 (37%), Positives = 62/124 (50%), Gaps = 10/124 (8%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDT-GFATCPMTQGSLVRFLVRSGQS-----AA  57
            LLD NVLIAL+ A HVHH  A+ WL      G+A+CP+TQ   +R + +         AA
Sbjct  4    LLDVNVLIALLDAGHVHHVRASQWLEQEIIHGWASCPLTQNGCLRIMTQPAYPEALSLAA  63

Query  58   AARDVVSAVQCTSRHEFWPDALSFAGVEVAG---VVGHRQVTDAYLAQLARSHDGQLATL  114
             A  +  A+   + H F  D  S    E      ++GH Q+ D+YL  LA  H  +  + 
Sbjct  64   VASRLAQAIAHPT-HAFVADDYSLLDAEQVNWQQMLGHWQIIDSYLLGLAVRHHCRFVSF  122

Query  115  DSGL  118
            DS L
Sbjct  123  DSRL  126


>gi|326772971|ref|ZP_08232255.1| toxin-antitoxin system, toxin component, PIN family [Actinomyces 
viscosus C505]
 gi|326637603|gb|EGE38505.1| toxin-antitoxin system, toxin component, PIN family [Actinomyces 
viscosus C505]
Length=146

 Score = 58.9 bits (141),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 44/124 (36%), Positives = 63/124 (51%), Gaps = 8/124 (6%)

Query  4    LLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLV--RSGQSAAAARD  61
            LLD NVL+AL +  H HH+  + W    D  +ATC +TQ + +R L+  R      AA D
Sbjct  9    LLDVNVLVALSLPNHAHHEVVSAWFDGVDQ-WATCSITQAAYLRLLMNPRVTGFEIAAAD  67

Query  62   VVS---AVQCTSRHEFWPDALSFA--GVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDS  116
            V+S    +     H F  D    A   +  + + G +QVTD +L  LA  H+  LAT+D 
Sbjct  68   VLSGLGGLTSLDDHVFLVDDAPPAEPSISFSRLKGPKQVTDLHLVDLAARHNAVLATMDG  127

Query  117  GLAH  120
             +A 
Sbjct  128  RMAQ  131


>gi|124515583|gb|EAY57093.1| conserved hypothetical protein [Leptospirillum rubarum]
Length=193

 Score = 51.6 bits (122),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 37/111 (34%), Positives = 59/111 (54%), Gaps = 9/111 (8%)

Query  4    LLDANVLIALVVAEHVHHDAAADWL-MASDTGFATCPMTQGSLVRFLVRSGQ----SAAA  58
            LLD NVLI L+ ++HV H A+ + L + +  G+++CP+T    +  +           + 
Sbjct  72   LLDINVLIVLLDSDHVFHSASREGLSLHATDGWSSCPLTDNGCMCIMSCPNDPDTIPVSR  131

Query  59   ARDVVSAVQCTSRHEFWPDALSF--AGVEVAGVV-GHRQVTD-AYLAQLAR  105
             RD +S       H+FWP+ + F  AGV VA    G RQ+TD ++L+   R
Sbjct  132  IRDRLSEAASGPPHQFWPEDVHFLDAGVAVASRTHGPRQITDLSWLSPSGR  182


>gi|190895067|ref|YP_001985360.1| hypothetical protein RHECIAT_PC0000733 [Rhizobium etli CIAT 652]
 gi|190700728|gb|ACE94810.1| hypothetical conserved protein [Rhizobium etli CIAT 652]
Length=82

 Score = 49.7 bits (117),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 29/79 (37%), Positives = 43/79 (55%), Gaps = 6/79 (7%)

Query  61   DVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
            ++V  ++    H FWPD +S  G   +    ++   QVTD YL  LA++H GQLAT D  
Sbjct  2    EIVRKLRSLPGHSFWPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKAHGGQLATFDRK  61

Query  118  L---AHLHGDVAVLIPTTT  133
            L   A   G+ A+ + TT+
Sbjct  62   LSAAAVTRGNSALQLITTS  80


>gi|333990807|ref|YP_004523421.1| hypothetical protein JDM601_2166 [Mycobacterium sp. JDM601]
 gi|333486774|gb|AEF36166.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=49

 Score = 48.5 bits (114),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 21/34 (62%), Positives = 26/34 (77%), Gaps = 0/34 (0%)

Query  63  VSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVT  96
           V A+    RHEFWP++LSFA V + GV+GHRQVT
Sbjct  5   VGALGRDPRHEFWPESLSFADVTLTGVIGHRQVT  38


>gi|16264146|ref|NP_436938.1| hypothetical protein SM_b20412 [Sinorhizobium meliloti 1021]
 gi|15140271|emb|CAC48798.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]
Length=54

 Score = 48.1 bits (113),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 33/50 (66%), Gaps = 1/50 (2%)

Query  1   VTVLLDANVLIALVVAEHVHHDAAADWLMA-SDTGFATCPMTQGSLVRFL  49
           +T LLD NVLIAL+   H+ HD A +W  +   T +ATCP+T+  ++R +
Sbjct  1   MTFLLDVNVLIALIDPSHIGHDDAHEWFASIGQTAWATCPITENGVIRIV  50


>gi|218459869|ref|ZP_03499960.1| hypothetical protein RetlK5_10369 [Rhizobium etli Kim 5]
Length=100

 Score = 47.8 bits (112),  Expect = 5e-04, Method: Compositional matrix adjust.
 Identities = 26/71 (37%), Positives = 37/71 (53%), Gaps = 3/71 (4%)

Query  52   SGQSAAAARDVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHD  108
            S  S A   ++V  ++    H FWPD +S  G   +    ++   QVTD YL  LA++  
Sbjct  11   SPGSPALVMEIVRKLRSLPGHSFWPDDVSLVGSGDIAPTKILTPGQVTDTYLLALAKARG  70

Query  109  GQLATLDSGLA  119
            GQLAT D  L+
Sbjct  71   GQLATFDRKLS  81


>gi|16264145|ref|NP_436937.1| hypothetical protein SM_b20411 [Sinorhizobium meliloti 1021]
 gi|15140270|emb|CAC48797.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]
Length=82

 Score = 45.1 bits (105),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 22/62 (36%), Positives = 36/62 (59%), Gaps = 3/62 (4%)

Query  61   DVVSAVQCTSRHEFWPDALSFAG---VEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSG  117
            ++V+ ++    H FWPD +S  G   +  + ++   QVTD YL  LA++  G+LAT D  
Sbjct  2    EIVAKLRSLPGHVFWPDDVSLVGSSDIIPSKILTSGQVTDTYLLALAKARGGKLATFDRK  61

Query  118  LA  119
            L+
Sbjct  62   LS  63


>gi|218289454|ref|ZP_03493682.1| PilT protein domain protein [Alicyclobacillus acidocaldarius 
LAA1]
 gi|218240322|gb|EED07504.1| PilT protein domain protein [Alicyclobacillus acidocaldarius 
LAA1]
Length=135

 Score = 42.4 bits (98),  Expect = 0.023, Method: Compositional matrix adjust.
 Identities = 39/139 (29%), Positives = 65/139 (47%), Gaps = 29/139 (20%)

Query  2    TVLLDANVLIALVVAEHVHHD-AAADWLMASDTG---FATCPMTQGSLVRFLVRSGQSAA  57
            +VLLD NV++  ++ +H HH  AA +  M ++ G       PM        L   G+   
Sbjct  3    SVLLDTNVILRFLLDDHPHHSPAATNLFMKAEQGEIKLVIDPMIVAECCYVL--EGKVYQ  60

Query  58   AARDVVSA----------VQCTSRHEFWPDALS--FAGVEVAGVVGHR-QVTDAYLAQLA  104
             +++++++          VQC        DAL     G+++   V HR    DAYL  LA
Sbjct  61   FSKELIASHLIPVLTHEGVQC--------DALMTVLDGLDI--YVEHRLDFADAYLIALA  110

Query  105  RSHDGQLATLDSGLAHLHG  123
            R+H  ++AT D+ +A +  
Sbjct  111  RNHRFEVATFDNKMARIEN  129



Lambda     K      H
   0.322    0.131    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 130457467840




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40