BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0669c Length=637 Score E Sequences producing significant alignments: (Bits) Value gi|15607809|ref|NP_215183.1| hydrolase [Mycobacterium tuberculos... 1297 0.0 gi|289573275|ref|ZP_06453502.1| hydrolase [Mycobacterium tubercu... 1295 0.0 gi|254549630|ref|ZP_05140077.1| hydrolase [Mycobacterium tubercu... 1295 0.0 gi|31791853|ref|NP_854346.1| hydrolase [Mycobacterium bovis AF21... 1295 0.0 gi|167967571|ref|ZP_02549848.1| hypothetical hydrolase [Mycobact... 1294 0.0 gi|254230994|ref|ZP_04924321.1| hypothetical protein TBCG_00661 ... 1293 0.0 gi|294993019|ref|ZP_06798710.1| hydrolase [Mycobacterium tubercu... 1292 0.0 gi|289749173|ref|ZP_06508551.1| hydrolase [Mycobacterium tubercu... 1252 0.0 gi|340625688|ref|YP_004744140.1| putative hydrolase [Mycobacteri... 1249 0.0 gi|289442067|ref|ZP_06431811.1| possible hydrolase [Mycobacteriu... 1185 0.0 gi|308370473|ref|ZP_07421641.2| hydrolase [Mycobacterium tubercu... 1116 0.0 gi|183981018|ref|YP_001849309.1| ceramidase [Mycobacterium marin... 1060 0.0 gi|289568610|ref|ZP_06448837.1| hydrolase [Mycobacterium tubercu... 1030 0.0 gi|307083175|ref|ZP_07492288.1| neutral/alkaline nonlysosomal ce... 1002 0.0 gi|323720892|gb|EGB29958.1| hypothetical protein TMMG_03375 [Myc... 779 0.0 gi|134099705|ref|YP_001105366.1| hydrolase [Saccharopolyspora er... 681 0.0 gi|291436562|ref|ZP_06575952.1| conserved hypothetical protein [... 665 0.0 gi|302557659|ref|ZP_07310001.1| neutral ceramidase [Streptomyces... 647 0.0 gi|333990637|ref|YP_004523251.1| ceramidase [Mycobacterium sp. J... 635 9e-180 gi|291008291|ref|ZP_06566264.1| hydrolase [Saccharopolyspora ery... 615 1e-173 gi|256389886|ref|YP_003111450.1| Neutral/alkaline nonlysosomal c... 553 4e-155 gi|326781031|ref|ZP_08240296.1| Ceramidase [Streptomyces cf. gri... 550 4e-154 gi|182440363|ref|YP_001828082.1| hypothetical protein SGR_6570 [... 550 4e-154 gi|239985835|ref|ZP_04706499.1| hypothetical protein SrosN1_0087... 549 4e-154 gi|291442789|ref|ZP_06582179.1| conserved hypothetical protein [... 549 5e-154 gi|297196055|ref|ZP_06913453.1| conserved hypothetical protein [... 546 5e-153 gi|294633770|ref|ZP_06712328.1| conserved hypothetical protein [... 539 6e-151 gi|325674944|ref|ZP_08154631.1| neutral ceramidase [Rhodococcus ... 499 4e-139 gi|312138151|ref|YP_004005487.1| ceramidase [Rhodococcus equi 10... 497 3e-138 gi|226304253|ref|YP_002764211.1| ceramidase [Rhodococcus erythro... 496 5e-138 gi|229494547|ref|ZP_04388310.1| alkaline ceramidase [Rhodococcus... 496 5e-138 gi|111021557|ref|YP_704529.1| hypothetical protein RHA1_ro04585 ... 494 2e-137 gi|54022614|ref|YP_116856.1| hypothetical protein nfa6470 [Nocar... 491 2e-136 gi|323720893|gb|EGB29959.1| hypothetical protein TMMG_03376 [Myc... 490 3e-136 gi|319949468|ref|ZP_08023527.1| hydrolase [Dietzia cinnamea P4] ... 481 2e-133 gi|333920233|ref|YP_004493814.1| hypothetical protein AS9A_2567 ... 471 1e-130 gi|262201941|ref|YP_003273149.1| ceramidase [Gordonia bronchiali... 446 5e-123 gi|115374581|ref|ZP_01461861.1| neutral/alkaline nonlysosomal ce... 444 2e-122 gi|6594292|dbj|BAA88409.1| alkaline ceramidase [Pseudomonas aeru... 431 3e-118 gi|218893188|ref|YP_002442057.1| alkaline ceramidase [Pseudomona... 430 4e-118 gi|222446995|pdb|2ZXC|A Chain A, Seramidase Complexed With C2 >g... 430 4e-118 gi|254239197|ref|ZP_04932520.1| conserved hypothetical protein [... 429 6e-118 gi|108760215|ref|YP_628881.1| alkaline ceramidase [Myxococcus xa... 429 7e-118 gi|116048768|ref|YP_792432.1| hypothetical protein PA14_53340 [P... 429 8e-118 gi|313105722|ref|ZP_07791985.1| alkaline ceramidase [Pseudomonas... 429 1e-117 gi|107100302|ref|ZP_01364220.1| hypothetical protein PaerPA_0100... 428 1e-117 gi|296390803|ref|ZP_06880278.1| alkaline ceramidase [Pseudomonas... 428 1e-117 gi|330802030|ref|XP_003289024.1| hypothetical protein DICPUDRAFT... 426 7e-117 gi|15596042|ref|NP_249536.1| hypothetical protein PA0845 [Pseudo... 424 2e-116 gi|152984039|ref|YP_001350019.1| hypothetical protein PSPA7_4675... 421 2e-115 >gi|15607809|ref|NP_215183.1| hydrolase [Mycobacterium tuberculosis H37Rv] gi|148660444|ref|YP_001281967.1| putative hydrolase [Mycobacterium tuberculosis H37Ra] gi|148821874|ref|YP_001286628.1| hydrolase [Mycobacterium tuberculosis F11] 47 more sequence titles Length=637 Score = 1297 bits (3357), Expect = 0.0, Method: Compositional matrix adjust. Identities = 637/637 (100%), Positives = 637/637 (100%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|289573275|ref|ZP_06453502.1| hydrolase [Mycobacterium tuberculosis K85] gi|289537706|gb|EFD42284.1| hydrolase [Mycobacterium tuberculosis K85] Length=637 Score = 1295 bits (3352), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/637 (99%), Positives = 636/637 (99%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAI DGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIFDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|254549630|ref|ZP_05140077.1| hydrolase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=637 Score = 1295 bits (3351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/637 (99%), Positives = 636/637 (99%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFW R Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWHR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|31791853|ref|NP_854346.1| hydrolase [Mycobacterium bovis AF2122/97] gi|121636590|ref|YP_976813.1| putative hydrolase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989062|ref|YP_002643749.1| putative hydrolase [Mycobacterium bovis BCG str. Tokyo 172] gi|31617440|emb|CAD93550.1| POSSIBLE HYDROLASE [Mycobacterium bovis AF2122/97] gi|121492237|emb|CAL70704.1| Possible hydrolase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772175|dbj|BAH24981.1| putative hydrolase [Mycobacterium bovis BCG str. Tokyo 172] gi|341600606|emb|CCC63276.1| possible hydrolase [Mycobacterium bovis BCG str. Moreau RDJ] Length=637 Score = 1295 bits (3350), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/637 (99%), Positives = 636/637 (99%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEV LSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVPLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|167967571|ref|ZP_02549848.1| hypothetical hydrolase [Mycobacterium tuberculosis H37Ra] Length=637 Score = 1294 bits (3348), Expect = 0.0, Method: Compositional matrix adjust. Identities = 635/637 (99%), Positives = 636/637 (99%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLIT+THTHAGPGGYCGYLL NLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITSTHTHAGPGGYCGYLLNNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|254230994|ref|ZP_04924321.1| hypothetical protein TBCG_00661 [Mycobacterium tuberculosis C] gi|124600053|gb|EAY59063.1| hypothetical protein TBCG_00661 [Mycobacterium tuberculosis C] Length=637 Score = 1293 bits (3345), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/637 (99%), Positives = 636/637 (99%), Gaps = 0/637 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYL YNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLPYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|294993019|ref|ZP_06798710.1| hydrolase [Mycobacterium tuberculosis 210] Length=634 Score = 1292 bits (3343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 634/634 (100%), Positives = 634/634 (100%), Gaps = 0/634 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREF 634 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREF Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREF 634 >gi|289749173|ref|ZP_06508551.1| hydrolase [Mycobacterium tuberculosis T92] gi|289689760|gb|EFD57189.1| hydrolase [Mycobacterium tuberculosis T92] Length=637 Score = 1252 bits (3240), Expect = 0.0, Method: Compositional matrix adjust. Identities = 621/638 (98%), Positives = 622/638 (98%), Gaps = 2/638 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIG-IPGEPT 419 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQE + R R L G PT Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQENCS-RSARANRSPLSDRYSGRPT 419 Query 420 IVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCA 479 IVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCA Sbjct 420 IVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCA 479 Query 480 LMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAV 539 LMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAV Sbjct 480 LMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAV 539 Query 540 EAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWD 599 EAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWD Sbjct 540 EAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWD 599 Query 600 VPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 VPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 600 VPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 >gi|340625688|ref|YP_004744140.1| putative hydrolase [Mycobacterium canettii CIPT 140010059] gi|340003878|emb|CCC43009.1| putative hydrolase [Mycobacterium canettii CIPT 140010059] Length=637 Score = 1249 bits (3233), Expect = 0.0, Method: Compositional matrix adjust. Identities = 621/636 (98%), Positives = 625/636 (99%), Gaps = 0/636 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDG+ARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGNARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSE NTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEHNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSP+AFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPAAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGE TVG IHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGETTVGAIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDG+ERRTGRPMFGAG MAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGQERRTGRPMFGAGCMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLAR AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARSAAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRR VASIVGA+LADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRTVASIVGAELADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQTVAELAEAMRDGRPV G RPRPTRELSWVRGAPADAGSFGAVIAEP ATYRPGQAVE Sbjct 481 MQTVAELAEAMRDGRPVMPGCRPRPTRELSWVRGAPADAGSFGAVIAEPLATYRPGQAVE 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV Sbjct 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV Sbjct 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 >gi|289442067|ref|ZP_06431811.1| possible hydrolase [Mycobacterium tuberculosis T46] gi|289414986|gb|EFD12226.1| possible hydrolase [Mycobacterium tuberculosis T46] Length=581 Score = 1185 bits (3065), Expect = 0.0, Method: Compositional matrix adjust. Identities = 580/581 (99%), Positives = 581/581 (100%), Gaps = 0/581 (0%) Query 57 LIVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSG 116 +IVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSG Sbjct 1 MIVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSG 60 Query 117 FRPATFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFP 176 FRPATFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFP Sbjct 61 FRPATFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFP 120 Query 177 KRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADY 236 KRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADY Sbjct 121 KRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADY 180 Query 237 LAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATP 296 LAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATP Sbjct 181 LAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATP 240 Query 297 IGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNP 356 IGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNP Sbjct 241 IGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNP 300 Query 357 FWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPG 416 FWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPG Sbjct 301 FWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPG 360 Query 417 EPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE 476 EPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE Sbjct 361 EPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE 420 Query 477 LCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPG 536 LCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPG Sbjct 421 LCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPG 480 Query 537 QAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSI 596 QAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSI Sbjct 481 QAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSI 540 Query 597 RWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 637 RWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV Sbjct 541 RWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV 581 >gi|308370473|ref|ZP_07421641.2| hydrolase [Mycobacterium tuberculosis SUMu003] gi|308371734|ref|ZP_07426011.2| hydrolase [Mycobacterium tuberculosis SUMu004] gi|308331815|gb|EFP20666.1| hydrolase [Mycobacterium tuberculosis SUMu003] gi|308335601|gb|EFP24452.1| hydrolase [Mycobacterium tuberculosis SUMu004] Length=547 Score = 1116 bits (2886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 546/547 (99%), Positives = 547/547 (100%), Gaps = 0/547 (0%) Query 91 LITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVSLSHG 150 +ITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVSLSHG Sbjct 1 MITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVSLSHG 60 Query 151 ELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTN 210 ELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTN Sbjct 61 ELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTN 120 Query 211 RNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPD 270 RNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPD Sbjct 121 RNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPD 180 Query 271 REFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGR 330 REFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGR Sbjct 181 REFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGR 240 Query 331 PMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNR 390 PMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNR Sbjct 241 PMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNR 300 Query 391 IHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAY 450 IHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAY Sbjct 301 IHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAY 360 Query 451 IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELS 510 IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELS Sbjct 361 IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELS 420 Query 511 WVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWV 570 WVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWV Sbjct 421 WVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWV 480 Query 571 RIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSAT 630 RIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSAT Sbjct 481 RIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSAT 540 Query 631 TREFTVV 637 TREFTVV Sbjct 541 TREFTVV 547 >gi|183981018|ref|YP_001849309.1| ceramidase [Mycobacterium marinum M] gi|183174344|gb|ACC39454.1| ceramidase [Mycobacterium marinum M] Length=637 Score = 1060 bits (2742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/636 (82%), Positives = 556/636 (88%), Gaps = 0/636 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIH RLRSRAFVFRDDSQD + RLLL+VA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHLRLRSRAFVFRDDSQDENPRLLLVVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELP+PMQNVN+EVLRRLA+ YGDTY+EQNTLIT THTHAGPGGYCGYL+YNLTT+GFRPA Sbjct 61 ELPMPMQNVNDEVLRRLAESYGDTYTEQNTLITTTHTHAGPGGYCGYLMYNLTTNGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESV HAH DVAPAEV LSHGEL+ ASINRSPSAFDRNP ADKAFFP R+D Sbjct 121 TFAAIVDGIVESVTHAHDDVAPAEVMLSHGELHSASINRSPSAFDRNPEADKAFFPNRID 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 P TTLVRIDRGE TVG IHFFATHGTSMTNRN +ISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PQTTLVRIDRGEHTVGAIHFFATHGTSMTNRNRMISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPL P A P +NTR+ GL QFEDA TQL T IG G Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLPPGAAPQCALENTRQIGLRQFEDASTQLGATTSIGTG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDAR TYVDL SV VRGE+TPDG+E RTG P GAG MAGT+EG GF GF QG+N FWD+ Sbjct 301 IDARLTYVDLSSVRVRGEFTPDGQEHRTGSPTVGAGGMAGTEEGKGFQGFHQGQNLFWDK 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LS AM+RLA A QAPKGIV+PA LPNR+HPFVQEI PVQLVRIGRLYLIGIPGEPT+ Sbjct 361 LSGAMFRLAGALGATQAPKGIVVPAGLPNRVHPFVQEIAPVQLVRIGRLYLIGIPGEPTV 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRR VASIVGA+LADVLCVGY NAYIHY+TTPEEYLEQRYEGGSTLFGRWEL A Sbjct 421 VAGLRLRRTVASIVGAELADVLCVGYCNAYIHYLTTPEEYLEQRYEGGSTLFGRWELPAF 480 Query 481 MQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVE 540 MQ VA LAEAMRDGRP+ G RPR R LSW R APAD GSFGAVIAEP+A+YRPG+AV+ Sbjct 481 MQIVAGLAEAMRDGRPIAPGPRPRLARPLSWGRAAPADTGSFGAVIAEPAASYRPGEAVQ 540 Query 541 AVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDV 600 A FVSALP+NDLRRG TYLEV RREG W R+ADDGDW+TSF W+RQGRAGS VSIRW++ Sbjct 541 AAFVSALPSNDLRRGDTYLEVQRREGQDWARVADDGDWSTSFHWERQGRAGSRVSIRWEI 600 Query 601 PGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 P DT PGQYRIVHHG AR+ G LT F+ATTREFTV Sbjct 601 PCDTAPGQYRIVHHGAARNGVGALTPFTATTREFTV 636 >gi|289568610|ref|ZP_06448837.1| hydrolase [Mycobacterium tuberculosis T17] gi|289542364|gb|EFD46012.1| hydrolase [Mycobacterium tuberculosis T17] Length=505 Score = 1030 bits (2664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 504/505 (99%), Positives = 505/505 (100%), Gaps = 0/505 (0%) Query 133 VEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGE 192 +EHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGE Sbjct 1 MEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGE 60 Query 193 ATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNP 252 ATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNP Sbjct 61 ATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNP 120 Query 253 GDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGS 312 GDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGS Sbjct 121 GDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGS 180 Query 313 VLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPT 372 VLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPT Sbjct 181 VLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPT 240 Query 373 AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVAS 432 AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVAS Sbjct 241 AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVAS 300 Query 433 IVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMR 492 IVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMR Sbjct 301 IVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMR 360 Query 493 DGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDL 552 DGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDL Sbjct 361 DGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDL 420 Query 553 RRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIV 612 RRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIV Sbjct 421 RRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIV 480 Query 613 HHGTARDRNGMLTAFSATTREFTVV 637 HHGTARDRNGMLTAFSATTREFTVV Sbjct 481 HHGTARDRNGMLTAFSATTREFTVV 505 >gi|307083175|ref|ZP_07492288.1| neutral/alkaline nonlysosomal ceramidase superfamily [Mycobacterium tuberculosis SUMu012] gi|308367045|gb|EFP55896.1| neutral/alkaline nonlysosomal ceramidase superfamily [Mycobacterium tuberculosis SUMu012] Length=490 Score = 1002 bits (2591), Expect = 0.0, Method: Compositional matrix adjust. Identities = 490/490 (100%), Positives = 490/490 (100%), Gaps = 0/490 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG Sbjct 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG 300 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR Sbjct 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDR 360 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI Sbjct 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL Sbjct 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 Query 481 MQTVAELAEA 490 MQTVAELAEA Sbjct 481 MQTVAELAEA 490 >gi|323720892|gb|EGB29958.1| hypothetical protein TMMG_03375 [Mycobacterium tuberculosis CDC1551A] Length=383 Score = 779 bits (2011), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/383 (100%), Positives = 383/383 (100%), Gaps = 0/383 (0%) Query 255 MSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVL 314 MSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVL Sbjct 1 MSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVL 60 Query 315 VRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAA 374 VRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAA Sbjct 61 VRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAA 120 Query 375 AQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIV 434 AQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIV Sbjct 121 AQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIV 180 Query 435 GADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDG 494 GADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDG Sbjct 181 GADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDG 240 Query 495 RPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRR 554 RPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRR Sbjct 241 RPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRR 300 Query 555 GGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHH 614 GGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHH Sbjct 301 GGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHH 360 Query 615 GTARDRNGMLTAFSATTREFTVV 637 GTARDRNGMLTAFSATTREFTVV Sbjct 361 GTARDRNGMLTAFSATTREFTVV 383 >gi|134099705|ref|YP_001105366.1| hydrolase [Saccharopolyspora erythraea NRRL 2338] gi|133912328|emb|CAM02441.1| possible hydrolase [Saccharopolyspora erythraea NRRL 2338] Length=681 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/642 (57%), Positives = 445/642 (70%), Gaps = 15/642 (2%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 GRGI+D TGE A+CGM+GYG+ DQ+ AG+H RLR R+FV + DG R+LLIV + P+ Sbjct 43 GRGISDATGEVAECGMMGYGRFDQQAAGLHTRLRVRSFVIA--TPDGGDRVLLIVVDSPM 100 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 ++V++ VLRRL + +GD Y+EQN LITATHTHAGPGGY +LLYNLTT+GF TF A Sbjct 101 IFESVHQAVLRRLGERFGDRYTEQNVLITATHTHAGPGGYSHHLLYNLTTTGFHRRTFDA 160 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 +VDGIVES E AHAD+APAE++L+HGEL AS NRS +AFDRNP +A FP +DP T+ Sbjct 161 VVDGIVESAERAHADLAPAELTLTHGELRDASANRSRAAFDRNPGDIRAHFPDAIDPQTS 220 Query 185 LVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQPDF 243 L+RI+R VG +++FATHGTSM+ N LIS DNKG+AAYHWER V DY A P F Sbjct 221 LLRIERSGRAVGAVNWFATHGTSMSGDNRLISADNKGYAAYHWEREVERVDYRADADPGF 280 Query 244 IAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQL-SGATPIGAGID 302 ++AFAQTN GDMSPN+D L P P+ +F+ TR G Q+E A QL S + G+D Sbjct 281 VSAFAQTNAGDMSPNLD--LRPPTTPE-DFERTRVNGHRQYEAAARQLGSPGARLTGGVD 337 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDRL 361 +R YVDL V+V E+T DG RT +P GA AG T++GP F GF +G NP WD + Sbjct 338 SRLVYVDLSDVVVSPEFTGDGRTHRTSKPAIGAPMAAGSTEDGPAFPGFAEGENPLWDAV 397 Query 362 S-RAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 S +Y A AQAPK IV+P NR++P+VQE VPVQLVR+GRL+LIGIPGE TI Sbjct 398 SGSVVYGPAPELRDAQAPKAIVVPVGAMNRVYPWVQEQVPVQLVRVGRLHLIGIPGEVTI 457 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 AGLRLRR VA IVGADLADVL GY N+Y HYVTTPEEY Q+YEGGSTLFGRW+L AL Sbjct 458 GAGLRLRRTVAGIVGADLADVLVAGYANSYFHYVTTPEEYDAQQYEGGSTLFGRWQLPAL 517 Query 481 MQTVAELAEAMRDGRPVTLGRRP------RPTRELSWVRGAPADAGSFGAVIAEPSATYR 534 Q VAELA AMRDGR + LG P + + + V P +FG V+ P +YR Sbjct 518 QQVVAELATAMRDGRRLPLGPVPPDLSGSQLSLQPPIVMDVPQPMRAFGDVLTGPRDSYR 577 Query 535 PGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHV 594 G+ V VF A P NDL R GTYL+V R EG W +ADDGDW+T W+R G A S V Sbjct 578 AGERVSVVFAGAHPGNDLHRRGTYLQVQRDEGGRWRTVADDGDWSTRLHWERDGIAASKV 637 Query 595 SIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 +I WDVPGD PG YRI +HG AR G ++AF+ TTR FTV Sbjct 638 TITWDVPGDVGPGGYRIRYHGHARHLTGAISAFTGTTRTFTV 679 >gi|291436562|ref|ZP_06575952.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC 14672] gi|291339457|gb|EFE66413.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC 14672] Length=658 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/644 (56%), Positives = 440/644 (69%), Gaps = 16/644 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRG+AD TGE A+ GM+GYG+ DQ+ AG+H RLR+RAFV D++ R++LIVA+ P Sbjct 19 VGRGLADATGEVAEVGMMGYGRFDQQAAGLHTRLRARAFVVVDEASG--RRVMLIVADSP 76 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + +V++ VLRRL + YGD Y+EQN LITATHTHAGPGGY +LLYN TT GF TF Sbjct 77 MIFSSVHQAVLRRLGEAYGDLYTEQNVLITATHTHAGPGGYAHHLLYNTTTFGFHRKTFE 136 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A+ DG+ E+ + AH D+AP+E+ LSHG L GAS+NRS SAF+RNP AD+ FP VDPHT Sbjct 137 AVADGLFEAAQRAHDDLAPSELVLSHGTLTGASVNRSRSAFERNPKADRDHFPDAVDPHT 196 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQPD 242 TL+R++R VG +++F H TSM+ N LIS DNKG+AAYHWER V DYL+ G P Sbjct 197 TLLRVERAGRVVGAVNWFPVHSTSMSGDNRLISADNKGYAAYHWEREVHDVDYLSDGSPA 256 Query 243 FIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQL-SGATPIGAGI 301 F++AFAQTN GDMSPN++ L P P+ +FD TR GL Q+E A QL + + Sbjct 257 FVSAFAQTNSGDMSPNLE--LEPPTTPE-DFDRTRANGLRQYEAAAAQLRQPGVELSGPV 313 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQGRNPFWDR 360 D+R YVDL V VR E+T DG RT +P GA AG+ ++GP F GF +G NPFWD Sbjct 314 DSRLVYVDLSDVTVRPEFTGDGRTHRTSKPCVGASMAAGSLEDGPAFPGFTEGENPFWDA 373 Query 361 LSRA-MYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPT 419 +S + +Y ++ A AQAPK + +P NR++P+VQE VPV LVRIGRL+LIGIPGE T Sbjct 374 VSDSVVYTVSPELARAQAPKDVFVPLGEMNRVYPWVQERVPVMLVRIGRLHLIGIPGEVT 433 Query 420 IVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCA 479 I AGLRLRR VA IVGADL DVL GY NAY HY+TTPEEY Q+YEGGSTLFGRW+L A Sbjct 434 ICAGLRLRRTVAEIVGADLDDVLVAGYANAYFHYLTTPEEYDAQQYEGGSTLFGRWQLPA 493 Query 480 LMQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGAPADAG----SFGAVIAEPSATY 533 L QT AELA A+RDG + LG + LS G DA FG V+ P Y Sbjct 494 LQQTAAELATALRDGTDLPLGPEAPDLSGKALSLQPGVVLDAPPLFRRFGDVLVGPRENY 553 Query 534 RPGQAVEAVFVSALPNNDLRRGGTYLEVVRRE-GASWVRIADDGDWATSFRWQRQGRAGS 592 R G+ VE VF A P NDL RG TYLEV R+E G +W +ADDGDWAT F W+R G A S Sbjct 554 RAGERVEVVFAGAHPGNDLHRGETYLEVQRQEPGGTWRTVADDGDWATRFHWKRDGIAAS 613 Query 593 HVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 V++ WDVP PG +RIV+HG AR G +T F+ T+ FTV Sbjct 614 RVTVTWDVPRGAAPGPHRIVYHGDARGVTGTVTPFTGTSPAFTV 657 >gi|302557659|ref|ZP_07310001.1| neutral ceramidase [Streptomyces griseoflavus Tu4000] gi|302475277|gb|EFL38370.1| neutral ceramidase [Streptomyces griseoflavus Tu4000] Length=685 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/643 (55%), Positives = 438/643 (69%), Gaps = 15/643 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRG+AD TGE A+ GM+GYG+ DQ+ AG+H RLR+RAFV D++ R++LIVA+ P Sbjct 47 VGRGLADATGEVAEVGMMGYGRFDQQAAGLHTRLRARAFVVVDEASG--RRVMLIVADSP 104 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + +V++ VLRRLA+ YG Y+ +N LITATHTH+GPGGY +LLYN TT GF TF Sbjct 105 MIFGSVHQAVLRRLAEAYGGLYTARNVLITATHTHSGPGGYSHHLLYNTTTFGFHRKTFE 164 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A+ DGI+E+ AH D+AP+E+ LSHG L GAS+NRS SAFDRNP AD+ FP VDPHT Sbjct 165 AVADGILEAARRAHDDLAPSELVLSHGTLTGASVNRSRSAFDRNPKADRDHFPDAVDPHT 224 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQPD 242 TL+R++R TVG +++F H TSM+ N LIS DNKG+AAYHWER V DYL+ G P Sbjct 225 TLLRVERAGRTVGAVNWFPVHSTSMSGDNRLISADNKGYAAYHWEREVNEVDYLSDGSPA 284 Query 243 FIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 F++AFAQTN GDMSPN+D L P P+ +F +TR +GL Q+E A QL + +D Sbjct 285 FVSAFAQTNSGDMSPNLD--LRPPTTPE-DFAHTRASGLLQYEAAAAQLGRGARLSGPVD 341 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQGRNPFWDRL 361 +R YVDL V VR E+T DG RT +P GA AG+ ++GP F GF +G NPFWD + Sbjct 342 SRLVYVDLSDVTVRPEFTGDGRTHRTSKPCVGASMAAGSMEDGPAFPGFEEGENPFWDAI 401 Query 362 SRA-MYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 S + +Y ++ AQAPK + +P NR++P+VQE VPV LVRIG LYLIGIPGE T+ Sbjct 402 SDSVIYTVSPELKQAQAPKDVFVPIGEMNRVYPWVQERVPVMLVRIGGLYLIGIPGEVTV 461 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 AGLRLRR VA IVGADL DVL GY NAY HY+TTPEEY Q+YEGGSTLFGRW+L AL Sbjct 462 CAGLRLRRTVAGIVGADLDDVLVAGYANAYFHYLTTPEEYDAQQYEGGSTLFGRWQLPAL 521 Query 481 MQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGAPADAG----SFGAVIAEPSATYR 534 QT A LA A+RDG + LG + LS G DA FG V+ P YR Sbjct 522 QQTAAALATALRDGTELPLGPEAPDLSGKALSLQPGVVLDAPPAFRKFGDVLVPPRENYR 581 Query 535 PGQAVEAVFVSALPNNDLRRGGTYLEV-VRREGASWVRIADDGDWATSFRWQRQGRAGSH 593 G+ VEAVF A P NDL RGGTYLEV +R+ +W +ADDGDW T F W+R G A S Sbjct 582 AGERVEAVFAGAHPGNDLHRGGTYLEVQLRKADGTWHTVADDGDWPTRFHWKRDGVAASQ 641 Query 594 VSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 V++ WDVP T G YR+V+HG AR G +T F+ TT FTV Sbjct 642 VTLTWDVPQGTPAGTYRLVYHGDARSLTGTITPFTGTTPAFTV 684 >gi|333990637|ref|YP_004523251.1| ceramidase [Mycobacterium sp. JDM601] gi|333486605|gb|AEF35997.1| ceramidase [Mycobacterium sp. JDM601] Length=647 Score = 635 bits (1637), Expect = 9e-180, Method: Compositional matrix adjust. Identities = 366/647 (57%), Positives = 439/647 (68%), Gaps = 18/647 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 +GRGIADITGE A+CGMLGYG + Q+T+G+H RLR+RAFV + + RLLL+V ELP Sbjct 1 MGRGIADITGEPAECGMLGYGVASQQTSGLHNRLRARAFVIVHPASE--VRLLLVVCELP 58 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 L +++V+ EVL RLA +G+ Y+ N ++TATHTH GPGGY + LYN T GFRP TFA Sbjct 59 LLLESVHREVLGRLAAAHGELYTVHNVMLTATHTHCGPGGYSDHRLYNSNTGGFRPQTFA 118 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGI E+VE AHAD+APA +SL+ G L+ AS NRSPSAF RNP A++A FP +DP T Sbjct 119 AIVDGICEAVERAHADLAPASLSLAVGRLHDASSNRSPSAFARNPEAERAHFPDAIDPQT 178 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ-PD 242 TL+RI+R VG +++FATHGTSMTNRN LISGDNKG+AAY WER G DYLA PD Sbjct 179 TLLRIERSGRLVGAVNWFATHGTSMTNRNTLISGDNKGYAAYRWERIDRGVDYLAPDPPD 238 Query 243 FIAAFAQTNPGDMSPNVDG-PLSPEAPPDREFDNTRRTGLCQFEDAFTQLSG-ATPIGAG 300 F+AAFAQTN GDMSPN++ P S P + EF+NTR G Q A +G + G Sbjct 239 FVAAFAQTNSGDMSPNLNHRPGS--GPTEDEFENTRIIGERQAAAAADLTTGHGAEVTGG 296 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPG-FHG-FRQGRNPFW 358 + A TYVDL V E+T DG RTG + GA A+AGTDEGPG H RQGRN Sbjct 297 LAALATYVDLSDFEVSPEFTGDGRTHRTGPAVAGAAALAGTDEGPGPLHPLLRQGRNCIV 356 Query 359 DRLSRA-MYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGE 417 D L A +YR+A A APKG+V P NR + PVQL+RIG+LYLIGIP E Sbjct 357 DSLVDATVYRVAPRLRDAHAPKGLVGPGSRLNRALTLMPNGGPVQLLRIGQLYLIGIPAE 416 Query 418 PTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 TIVAGLRLRR VA+IVGA+L DVL GY+N Y+HYVTTPEEY EQRYEGGSTLFGRWEL Sbjct 417 VTIVAGLRLRRTVAAIVGAELRDVLVAGYSNGYLHYVTTPEEYQEQRYEGGSTLFGRWEL 476 Query 478 CALMQTVAELAEAMRDGRPVTLGRR----PRPTRELSWVRG-APADAGSFGAVIAEPSAT 532 AL Q A LA AMRD RP +G PR R V PA FG V+A P A Sbjct 477 AALQQVAAGLATAMRDRRPAPVGNAAAEPPRRRRSRRRVSADEPAAGRRFGEVLAPPLAH 536 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGAS---WVRIADDGDWATSFRWQRQGR 589 Y+PG V AVF A PNNDL RGGTYL V R+ G + W +ADDGDW+T+FRW+R GR Sbjct 537 YQPGATVTAVFAGAHPNNDLHRGGTYLRVERQTGGAEGGWSTVADDGDWSTTFRWRRAGR 596 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 GS V++ W VP +T G+YR+ + G AR G TAF+ +T F + Sbjct 597 RGSTVTVTWTVPENTAAGRYRLRYDGDARGLEGQRTAFTGSTEPFEI 643 >gi|291008291|ref|ZP_06566264.1| hydrolase [Saccharopolyspora erythraea NRRL 2338] Length=582 Score = 615 bits (1585), Expect = 1e-173, Method: Compositional matrix adjust. Identities = 331/581 (57%), Positives = 400/581 (69%), Gaps = 13/581 (2%) Query 66 MQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAI 125 ++V++ VLRRL + +GD Y+EQN LITATHTHAGPGGY +LLYNLTT+GF TF A+ Sbjct 3 FESVHQAVLRRLGERFGDRYTEQNVLITATHTHAGPGGYSHHLLYNLTTTGFHRRTFDAV 62 Query 126 VDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTL 185 VDGIVES E AHAD+APAE++L+HGEL AS NRS +AFDRNP +A FP +DP T+L Sbjct 63 VDGIVESAERAHADLAPAELTLTHGELRDASANRSRAAFDRNPGDIRAHFPDAIDPQTSL 122 Query 186 VRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQPDFI 244 +RI+R VG +++FATHGTSM+ N LIS DNKG+AAYHWER V DY A P F+ Sbjct 123 LRIERSGRAVGAVNWFATHGTSMSGDNRLISADNKGYAAYHWEREVERVDYRADADPGFV 182 Query 245 AAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQL-SGATPIGAGIDA 303 +AFAQTN GDMSPN+D L P P+ +F+ TR G Q+E A QL S + G+D+ Sbjct 183 SAFAQTNAGDMSPNLD--LRPPTTPE-DFERTRVNGHRQYEAAARQLGSPGARLTGGVDS 239 Query 304 RFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDRLS 362 R YVDL V+V E+T DG RT +P GA AG T++GP F GF +G NP WD +S Sbjct 240 RLVYVDLSDVVVSPEFTGDGRTHRTSKPAIGAPMAAGSTEDGPAFPGFAEGENPLWDAVS 299 Query 363 -RAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIV 421 +Y A AQAPK IV+P NR++P+VQE VPVQLVR+GRL+LIGIPGE TI Sbjct 300 GSVVYGPAPELRDAQAPKAIVVPVGAMNRVYPWVQEQVPVQLVRVGRLHLIGIPGEVTIG 359 Query 422 AGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALM 481 AGLRLRR VA IVGADLADVL GY N+Y HYVTTPEEY Q+YEGGSTLFGRW+L AL Sbjct 360 AGLRLRRTVAGIVGADLADVLVAGYANSYFHYVTTPEEYDAQQYEGGSTLFGRWQLPALQ 419 Query 482 QTVAELAEAMRDGRPVTLGRRP------RPTRELSWVRGAPADAGSFGAVIAEPSATYRP 535 Q VAELA AMRDGR + LG P + + + V P +FG V+ P +YR Sbjct 420 QVVAELATAMRDGRRLPLGPVPPDLSGSQLSLQPPIVMDVPQPMRAFGDVLTGPRDSYRA 479 Query 536 GQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVS 595 G+ V VF A P NDL R GTYL+V R EG W +ADDGDW+T W+R G A S V+ Sbjct 480 GERVSVVFAGAHPGNDLHRRGTYLQVQRDEGGRWRTVADDGDWSTRLHWERDGIAASKVT 539 Query 596 IRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 I WDVPGD PG YRI +HG AR G ++AF+ TTR FTV Sbjct 540 ITWDVPGDVGPGGYRIRYHGHARHLTGAISAFTGTTRTFTV 580 >gi|256389886|ref|YP_003111450.1| Neutral/alkaline nonlysosomal ceramidase [Catenulispora acidiphila DSM 44928] gi|256356112|gb|ACU69609.1| Neutral/alkaline nonlysosomal ceramidase [Catenulispora acidiphila DSM 44928] Length=643 Score = 553 bits (1424), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 326/656 (50%), Positives = 403/656 (62%), Gaps = 48/656 (7%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 GRGIADITGE A+CG+LGYG +Q+ AG+H RLR+RAF DG+ R+LL++ +LPL Sbjct 6 GRGIADITGEIAECGLLGYGLPEQQAAGLHTRLRARAFAL----ADGERRMLLVICDLPL 61 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 +V + VLRRL +Y +E N +I+ATHTH GPGGY + +YN TT GFRP TF A Sbjct 62 VFSSVTQAVLRRLPAVY----TEANVVISATHTHCGPGGYSHHAVYNGTTGGFRPQTFRA 117 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIVE+ A AD+ PA + L+ GEL+ AS+NRS AF+RNP ADKA FP VDP TT Sbjct 118 IVDGIVEAARRAIADLRPATLRLNRGELHDASVNRSRRAFERNPSADKAAFPDAVDPATT 177 Query 185 LVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA--GQPD 242 L+ I+R V +I +FA H TSMTNRN L+S DNKG+AAYHWER V G DYLA +P Sbjct 178 LLTIERDGLPVALIDWFAVHNTSMTNRNRLVSADNKGYAAYHWEREVSGFDYLAEDAEPA 237 Query 243 FIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSG---ATPIG 298 + AFAQTN GDMSPN++ L P P + EF+NTR G Q+E A L+G A + Sbjct 238 LVTAFAQTNAGDMSPNLN--LRPGSGPTEDEFENTRIIGTRQYEAAAKLLAGRENAEVLD 295 Query 299 AGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGP-GFHGFRQGRNP 356 G+D R +VD+ V V ++ DG RT + GA A AG +GP G+ NP Sbjct 296 GGLDHRLVHVDMADVRVSPRFSGDGLPHRTSHAVPGATAFAGALPDGPTGWRFVHPEINP 355 Query 357 FWDRLSR-AMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIP 415 F D +SR +YRLAR QAPK + P L NRI PF QEI+P+QL+RIG LYL+ +P Sbjct 356 FLDTVSRDGIYRLARRLRETQAPKTLAAPISLLNRIVPFGQEILPIQLLRIGSLYLLCLP 415 Query 416 GEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRW 475 E TIVAGLRLRR VA G D V+ +GY NAY HYVTTPEEY Q YEG STLFGRW Sbjct 416 FEVTIVAGLRLRRTVAEASGTDPDHVIVMGYANAYGHYVTTPEEYDAQMYEGASTLFGRW 475 Query 476 ELCALMQTVAELAEAMRDGRPVTLG-----------RRPRPTRELSWVRGAPADAGSFGA 524 +L AL Q A LA AMR+GR + G R+P P R AD Sbjct 476 QLPALQQNAARLATAMREGRQIAPGRAAPDLSARHRRQPTPPR---------ADGRPPTV 526 Query 525 VIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRW 584 I E + + + F + P +D RRGGTY E+ RREG W RIADDGDW+T RW Sbjct 527 DIGEELSFAWDEKTLAVEFAAVHPFHDPRRGGTYYEIQRREGLYWHRIADDGDWSTRMRW 586 Query 585 QR----QGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 R S V I W VP +T G+YR+V+ G + AF A +REF + Sbjct 587 TRLPSPHDTTLSKVRIEWRVPPETPRGRYRLVYRG-----DTGQVAFEARSREFDL 637 >gi|326781031|ref|ZP_08240296.1| Ceramidase [Streptomyces cf. griseus XylebKG-1] gi|326661364|gb|EGE46210.1| Ceramidase [Streptomyces griseus XylebKG-1] Length=686 Score = 550 bits (1416), Expect = 4e-154, Method: Compositional matrix adjust. Identities = 298/644 (47%), Positives = 392/644 (61%), Gaps = 15/644 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRGI+D+TGEAA+ GM+GY DQ+T+GIHQR RSRAFV D + R++ + A+L Sbjct 46 VGRGISDVTGEAAETGMMGYSSFDQKTSGIHQRQRSRAFVVVDRASG--KRVVYVNADLA 103 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V + V+ RL + YG Y E+N L++ATHTH+GPGGY + YNL+ GF+ T+ Sbjct 104 MIFQSVRQGVMARLKERYGSLYGEENVLLSATHTHSGPGGYSHNVAYNLSVLGFQKETYR 163 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGI ESV AH D+ P +SL G L AS+NRS AFDRNP AD+A FP +DP Sbjct 164 AIVDGITESVAKAHEDLKPGTMSLGTGTLTNASVNRSREAFDRNPAADRAAFPDAIDPAM 223 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +GE G I +FATH TS+TN+N LIS DNKG+AAY WE G YL P F Sbjct 224 TVLRFKQGERDAGAISWFATHNTSITNKNTLISPDNKGYAAYAWEHDHEGVRYLDDTPGF 283 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 +AAF TN GDMSPN++ L P P + EF+N R G Q + A G P+ G+D Sbjct 284 VAAFPNTNAGDMSPNLN--LKPGSGPTEDEFENARVIGERQLDKAREIYDGTRPVSGGVD 341 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPFWDR 360 +R YVD+ +V VR EY PDG+E RT + GA +AG+ ++GP F +G R P Sbjct 342 SRLAYVDMENVTVRPEYAPDGKEHRTCPAVVGASTLAGSVEDGPAIPLFEEGMRTPIAPI 401 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 L A Q PK ++P L + +HP + +P+Q+++IG L+L+ PGE TI Sbjct 402 LEALRVDTPSWLATCQYPKASLVPTGLLSNVHPVTPKRLPLQIMKIGELHLVAAPGEFTI 461 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 +GLR+RR VA +G L VL GY NAY YVTTPEEY Q YEGGSTL+GR+ L A Sbjct 462 ASGLRVRRTVARQLGVPLDRVLLQGYANAYSQYVTTPEEYDTQNYEGGSTLYGRYTLPAY 521 Query 481 MQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGA----PADAGSFGAVIAEPSATYR 534 Q +A+++R+G + G P R+ ++ G P +FG V+ P +Y Sbjct 522 QQEYDRIAKSLREGTTLDRGTMPADESGRQFTFQTGVVYDNPPSGKAFGGVLKAPEPSYA 581 Query 535 PGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQR-QGRAG-S 592 G F + P N+LRRG T+LEV R SW R+ DDGDW T++RW R G G S Sbjct 582 RGSTATVEFATGHPKNNLRRGSTFLEVQRLVNGSWQRVLDDGDWGTTYRWTRLNGLTGTS 641 Query 593 HVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 +I WD+ DT PG YRIVHHG A+ G +T F+ TT FTV Sbjct 642 KATITWDIAADTDPGTYRIVHHGDAKSLLGKITPFTGTTGGFTV 685 >gi|182440363|ref|YP_001828082.1| hypothetical protein SGR_6570 [Streptomyces griseus subsp. griseus NBRC 13350] gi|178468879|dbj|BAG23399.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus NBRC 13350] Length=686 Score = 550 bits (1416), Expect = 4e-154, Method: Compositional matrix adjust. Identities = 296/644 (46%), Positives = 391/644 (61%), Gaps = 15/644 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRGI+D+TGEAA+ GM+GY DQ+T+GIHQR RSRAFV D + R++ + A+L Sbjct 46 VGRGISDVTGEAAETGMMGYSSFDQKTSGIHQRQRSRAFVVVDRASG--KRVVYVNADLA 103 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V + V+ RL + YG Y E+N L++ATHTH+GPGGY + YNL+ GF+ T+ Sbjct 104 MIFQSVRQGVMARLKERYGSLYGEENVLLSATHTHSGPGGYSHNVAYNLSVLGFQKETYR 163 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGI ESV AH D+ P +SL G L AS+NRS AFDRNP AD+A FP +DP Sbjct 164 AIVDGITESVAKAHEDLKPGTMSLGTGTLTNASVNRSREAFDRNPAADRAAFPDAIDPAM 223 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +GE G I +FATH TS+TN+N LIS DNKG+AAY WE G YL P F Sbjct 224 TVLRFKQGERDAGAISWFATHNTSITNKNTLISPDNKGYAAYAWEHDHEGVRYLDDTPGF 283 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 +AAF TN GDMSPN++ L P P + EF+N R G Q + A G P+ G+D Sbjct 284 VAAFPNTNAGDMSPNLN--LKPGSGPTEDEFENARVIGERQLDKAREIYDGTRPVSGGVD 341 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPFWDR 360 +R YVD+ +V VR EY PDG+E RT + GA +AG+ ++GP F +G R P Sbjct 342 SRLAYVDMENVTVRPEYAPDGKEHRTCPAVVGASTLAGSVEDGPAIPLFEEGMRTPIAPI 401 Query 361 LSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTI 420 L A Q PK ++P L + +HP + +P+Q+++IG L+L+ PGE TI Sbjct 402 LEALRVDTPSWLATCQYPKASLVPTGLLSNVHPVTPKRLPLQIMKIGELHLVAAPGEFTI 461 Query 421 VAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCAL 480 +GLR+RR VA +G L VL GY NAY YVTTPEEY Q YEGGSTL+GR+ L A Sbjct 462 ASGLRVRRTVARQLGVPLDRVLLQGYANAYSQYVTTPEEYDTQNYEGGSTLYGRYTLPAY 521 Query 481 MQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGA----PADAGSFGAVIAEPSATYR 534 Q +A+++R+G + G P R+ ++ G P +FG V+ P +Y Sbjct 522 QQEYDRIAKSLREGTTLDRGTMPADESGRQFTFQTGVVYDNPPSGKAFGGVLKAPEPSYA 581 Query 535 PGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQG--RAGS 592 G F + P N+LRRG T+LEV R SW R+ DDGDW T++RW R S Sbjct 582 RGSTATVEFATGHPKNNLRRGSTFLEVQRLVNGSWQRVLDDGDWGTTYRWTRLNDLTGTS 641 Query 593 HVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 +I WD+ DT PG YRIVHHG A+ G +T+F+ TT FTV Sbjct 642 KATITWDIAADTDPGTYRIVHHGDAKSLLGKITSFTGTTGGFTV 685 >gi|239985835|ref|ZP_04706499.1| hypothetical protein SrosN1_00872 [Streptomyces roseosporus NRRL 11379] Length=686 Score = 549 bits (1415), Expect = 4e-154, Method: Compositional matrix adjust. Identities = 299/646 (47%), Positives = 395/646 (62%), Gaps = 19/646 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRGIAD+TGEAA+ GM+GY DQ+T+GIHQR RSRAFV D + R + + A+L Sbjct 46 VGRGIADVTGEAAETGMMGYSSFDQKTSGIHQRQRSRAFVVVDKASG--KRAVYVNADLA 103 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V + V+ RL + YG Y E N L++ATHTH+GPGGY + YNL+ GF+ T+ Sbjct 104 MIFQSVRQGVMARLTERYGSLYGEDNVLLSATHTHSGPGGYSHNVAYNLSVLGFQKETYR 163 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGI ESV AH D+ P +SL G L AS NRS AFDRNP AD+A FP +DP Sbjct 164 AIVDGITESVAEAHEDLKPGTMSLGTGTLTNASANRSREAFDRNPAADRAAFPDGIDPAM 223 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +G+ G I +FATH TS+TN+N LIS DNKG+A+Y WE G YL P F Sbjct 224 TVLRFKQGDKDAGAISWFATHNTSITNKNTLISPDNKGYASYAWEHDHEGVRYLDDTPGF 283 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 +AAF TN GDMSPN++ L P P + EF+N R G Q + A A P+ G+D Sbjct 284 VAAFPNTNAGDMSPNLN--LKPGSGPTEDEFENARIIGERQLDKAREIYDDARPVAGGVD 341 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPFWDR 360 +R YVD+ +V VR EYTPDGEE RT + GA +AG+ ++GP F +G R P Sbjct 342 SRLAYVDMENVTVRPEYTPDGEEHRTCPAVVGASTLAGSVEDGPAIPLFEEGMRTPIAPI 401 Query 361 LSRAMYRLARPT--AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L R+ P+ A Q PK ++P L + +HP + +P+Q+++IG L+L+ PGE Sbjct 402 LE--ALRVDTPSWLATCQYPKASLIPTGLLSNVHPVTPKRLPLQIMKIGELHLVAAPGEF 459 Query 419 TIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 TI +GLR+RR VA +G L VL GY NAY YVTTPEEY Q YEGGSTL+GR+ L Sbjct 460 TIASGLRVRRTVAEQLGVPLDRVLLQGYANAYSQYVTTPEEYDAQNYEGGSTLYGRYTLP 519 Query 479 ALMQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGA----PADAGSFGAVIAEPSAT 532 A Q A +A+++R G + G P R+ ++ G P +FGAV+ P + Sbjct 520 AYQQEYARIAQSLRAGTALDRGTVPADESGRQFTFQTGVVYDNPPSGKAFGAVLKAPEGS 579 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQR-QGRAG 591 Y G F + P N++RRG T+LEV R E +W R+ DDGDW T++RW R G G Sbjct 580 YARGSTATVEFATGHPKNNVRRGSTFLEVQRLENGTWKRVLDDGDWETTYRWTRLNGLTG 639 Query 592 -SHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 S ++ W + DT PG YRIVHHG A++ G +T F+ T FTV Sbjct 640 TSKATVTWKIAADTAPGTYRIVHHGDAKNLLGKITPFTGATGTFTV 685 >gi|291442789|ref|ZP_06582179.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 15998] gi|291345736|gb|EFE72640.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 15998] Length=695 Score = 549 bits (1415), Expect = 5e-154, Method: Compositional matrix adjust. Identities = 299/646 (47%), Positives = 395/646 (62%), Gaps = 19/646 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRGIAD+TGEAA+ GM+GY DQ+T+GIHQR RSRAFV D + R + + A+L Sbjct 55 VGRGIADVTGEAAETGMMGYSSFDQKTSGIHQRQRSRAFVVVDKASG--KRAVYVNADLA 112 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V + V+ RL + YG Y E N L++ATHTH+GPGGY + YNL+ GF+ T+ Sbjct 113 MIFQSVRQGVMARLTERYGSLYGEDNVLLSATHTHSGPGGYSHNVAYNLSVLGFQKETYR 172 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGI ESV AH D+ P +SL G L AS NRS AFDRNP AD+A FP +DP Sbjct 173 AIVDGITESVAEAHEDLKPGTMSLGTGTLTNASANRSREAFDRNPAADRAAFPDGIDPAM 232 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +G+ G I +FATH TS+TN+N LIS DNKG+A+Y WE G YL P F Sbjct 233 TVLRFKQGDKDAGAISWFATHNTSITNKNTLISPDNKGYASYAWEHDHEGVRYLDDTPGF 292 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 +AAF TN GDMSPN++ L P P + EF+N R G Q + A A P+ G+D Sbjct 293 VAAFPNTNAGDMSPNLN--LKPGSGPTEDEFENARIIGERQLDKAREIYDDARPVAGGVD 350 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPFWDR 360 +R YVD+ +V VR EYTPDGEE RT + GA +AG+ ++GP F +G R P Sbjct 351 SRLAYVDMENVTVRPEYTPDGEEHRTCPAVVGASTLAGSVEDGPAIPLFEEGMRTPIAPI 410 Query 361 LSRAMYRLARPT--AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L R+ P+ A Q PK ++P L + +HP + +P+Q+++IG L+L+ PGE Sbjct 411 LE--ALRVDTPSWLATCQYPKASLIPTGLLSNVHPVTPKRLPLQIMKIGELHLVAAPGEF 468 Query 419 TIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 TI +GLR+RR VA +G L VL GY NAY YVTTPEEY Q YEGGSTL+GR+ L Sbjct 469 TIASGLRVRRTVAEQLGVPLDRVLLQGYANAYSQYVTTPEEYDAQNYEGGSTLYGRYTLP 528 Query 479 ALMQTVAELAEAMRDGRPVTLGRRP--RPTRELSWVRGA----PADAGSFGAVIAEPSAT 532 A Q A +A+++R G + G P R+ ++ G P +FGAV+ P + Sbjct 529 AYQQEYARIAQSLRAGTALDRGTVPADESGRQFTFQTGVVYDNPPSGKAFGAVLKAPEGS 588 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQR-QGRAG 591 Y G F + P N++RRG T+LEV R E +W R+ DDGDW T++RW R G G Sbjct 589 YARGSTATVEFATGHPKNNVRRGSTFLEVQRLENGTWKRVLDDGDWETTYRWTRLNGLTG 648 Query 592 -SHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 S ++ W + DT PG YRIVHHG A++ G +T F+ T FTV Sbjct 649 TSKATVTWKIAADTAPGTYRIVHHGDAKNLLGKITPFTGATGTFTV 694 >gi|297196055|ref|ZP_06913453.1| conserved hypothetical protein [Streptomyces pristinaespiralis ATCC 25486] gi|197723306|gb|EDY67214.1| conserved hypothetical protein [Streptomyces pristinaespiralis ATCC 25486] Length=679 Score = 546 bits (1407), Expect = 5e-153, Method: Compositional matrix adjust. Identities = 305/648 (48%), Positives = 402/648 (63%), Gaps = 22/648 (3%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGRGI+D+TGEAA+ GM+GY +Q+ +GIHQR RSRAFV D + R++ + A+L Sbjct 38 VGRGISDVTGEAAEVGMMGYSSFEQKASGIHQRQRSRAFVVADRTTG--KRVVYVNADLA 95 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V + V+ L YG YSE+N L++ATHTHAG GG+ +L YNL + GF+ T+ Sbjct 96 MIFQSVQQGVIAGLKARYGSLYSEENVLLSATHTHAGSGGHSHHLAYNLASLGFQKDTYR 155 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIVDGIVESV AH D+AP + L GEL AS+NRS +AF++NP DKA FP +DP Sbjct 156 AIVDGIVESVAEAHEDLAPGTIRLGRGELTDASVNRSRTAFEKNPAGDKAAFPGAIDPAM 215 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +G+ +G I +FATH TS+TN+N L+S DNKG+AAY WE G YL Q F Sbjct 216 TVLRFRQGDRDIGAISWFATHNTSLTNKNTLLSPDNKGYAAYEWEHDDQGVRYLENQEGF 275 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSG-ATPIGAGI 301 +AAF TN GDMSPN++ L P P + EF+NTR G QF A G A P+ G+ Sbjct 276 VAAFPNTNAGDMSPNLN--LKPGSGPTEDEFENTRIIGDRQFRKAQEIYDGAAVPLSGGV 333 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQGRNPFWDR 360 D+R +V++ V V G+YTPDG+E RT M GA +AG+ ++GP GF +G N + Sbjct 334 DSRMRFVNMEEVTVGGKYTPDGKEHRTCPAMVGASTLAGSVEDGPAIPGFTEGMNSPVAK 393 Query 361 LSRAMYRLARPT--AAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + P + Q PK ++P L N + P ++PVQ+V+IG+ YL+ P E Sbjct 394 LLEP-FDIDPPEWLVSCQYPKANLVPTGLVNAVTPTTPTVLPVQIVKIGQFYLVAGPAEY 452 Query 419 TIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 TIV+GLR+RR VA +G L +VL GY NAY YVTTPEEY Q+YEGGSTL+GR+ L Sbjct 453 TIVSGLRIRRTVAQELGVPLENVLMQGYANAYSQYVTTPEEYDLQQYEGGSTLYGRYTLP 512 Query 479 ALMQTVAELAEAMRDGRPVTLGRRPRPT----RELSWVRGA----PADAGSFGAVIAEPS 530 A Q A LA ++RDG T+GR P P R+ S G P FG V+ EP+ Sbjct 513 AYQQEFASLAASLRDG--TTIGRGPSPADQSGRQTSLQTGVVMDNPPSGRKFGDVLTEPA 570 Query 531 ATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQR-QGR 589 +Y G V A FV+ P N+LRRGGT+LEV + WVR DDGDW T++RW R G Sbjct 571 ESYGQGATVTAEFVTGHPKNNLRRGGTFLEVQQLVDGRWVRRLDDGDWDTTYRWVRLNGV 630 Query 590 AG-SHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 +G S + W V T G YRIVH G ++ G +T FS TR FTV Sbjct 631 SGTSKAVVTWKVAPGTPKGTYRIVHFGDSKSLFGKITGFSGATRPFTV 678 >gi|294633770|ref|ZP_06712328.1| conserved hypothetical protein [Streptomyces sp. e14] gi|292830412|gb|EFF88763.1| conserved hypothetical protein [Streptomyces sp. e14] Length=672 Score = 539 bits (1389), Expect = 6e-151, Method: Compositional matrix adjust. Identities = 303/651 (47%), Positives = 399/651 (62%), Gaps = 32/651 (4%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VGR +ADITGE A+ GY D +T G+HQR R+RAF+ D + + R+ ++VAE+ Sbjct 35 VGRAVADITGEPANSDKDGYLAPDYKTVGLHQRQRARAFIMADPATN--KRVAIVVAEVN 92 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q V +EVLRRL +GD Y+++N L+++THTH+ PGG+ Y YN+ GF+P F Sbjct 93 MVPQAVRDEVLRRLEHRFGDKYTKENLLLSSTHTHSAPGGFNYYNFYNIAAGGFKPKNFD 152 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 + VDG+ ++V A AD+AP + ++ GEL AS NRS AFDR+P AD+AFFP +DP T Sbjct 153 SFVDGVYDAVVKADADLAPGSLDMAIGELNNASANRSRDAFDRDPAADRAFFPDAIDPQT 212 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQPD 242 TL+++ R VG + +FATHGTSM N LIS DNKG+AAYHWE V DYL+ P Sbjct 213 TLLQMSRNGRPVGALDWFATHGTSMDKTNRLISPDNKGYAAYHWEHDVEHVDYLSDNDPA 272 Query 243 FIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGA--TPIGA 299 F+A FAQTN GDM+P+++ L P P + + +NT+ G Q++ A QLS T I Sbjct 273 FVAGFAQTNSGDMTPDLN--LRPGSGPTEDDVENTKIIGDRQYQ-AAAQLSTGPKTAIDG 329 Query 300 GIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDE-GPGFHGFRQ--GRNP 356 ID RFTYVD+G V YT DG+ T FG G AG+ E GPG + G NP Sbjct 330 PIDYRFTYVDMGDTTVDPAYTGDGKSHSTCSGAFGVGFAAGSKEDGPGVDFLNEGTGNNP 389 Query 357 FWDRLSRAMYRLARPTAAAQAPKGIVMPA----RLPNRIHPFVQEIVPVQLVRIGRLYLI 412 +DR+S A+Y+ + QAPK I++ + PN I+P+QLVRIG+LYLI Sbjct 390 LFDRISGALYQASPALKDCQAPKDILLASGDLGLTPN--------ILPIQLVRIGQLYLI 441 Query 413 GIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLF 472 IP E TIVAGLRLRR V+ IVGA L +VL GY+N+Y YVTTPEEY + YE G T+F Sbjct 442 AIPQEATIVAGLRLRRTVSQIVGAPLQNVLVAGYSNSYAGYVTTPEEYDQGDYEAGHTMF 501 Query 473 GRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPA---DAGS----FGAV 525 GRW L A Q VAELA M RP ++ P P + + VR AP DA + FG V Sbjct 502 GRWTLPAYQQHVAELARDMAGNRPTSVTIEP-PDKSSTLVRSAPGPLFDAPALFHRFGDV 560 Query 526 IAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQ 585 + +P A+Y G V+ F A P+ DLRRG TYL+V R W R+ DDGDW+T F W Sbjct 561 LLQPQASYYRGDEVKVEFDGANPDTDLRRGSTYLKVERLGANGWQRMYDDGDWSTRFVWT 620 Query 586 RQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 QG S +++ WD+P D PGQYR+ + G A+ G FS + FTV Sbjct 621 DQGLGVSKITVTWDIPADAEPGQYRVTYLGDAKPLIGDPVPFSGVSNTFTV 671 >gi|325674944|ref|ZP_08154631.1| neutral ceramidase [Rhodococcus equi ATCC 33707] gi|325554530|gb|EGD24205.1| neutral ceramidase [Rhodococcus equi ATCC 33707] Length=685 Score = 499 bits (1286), Expect = 4e-139, Method: Compositional matrix adjust. Identities = 295/647 (46%), Positives = 388/647 (60%), Gaps = 24/647 (3%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VG G++D+TG A+ GM+GY + DQR G+HQR R RA+VF D D R++ A+ Sbjct 48 VGVGLSDMTGPVAENGMMGYSQFDQRAEGLHQRTRVRAYVFADAD---DNRVVYTCADTC 104 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q V++ VL RLA YGD Y+E+N ++TA H+HA GG Y+L T GF+P F Sbjct 105 MVFQAVHDAVLARLAAKYGDLYTEKNVMLTAVHSHAACGGASQDYAYSLATLGFQPQVFD 164 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A VDG+VE++ AH ++A V+ EL AS+NRS +AFDRNP DK ++P +D Sbjct 165 AEVDGVVEAIVAAHDNLAAGTVAYGRSELKDASVNRSRAAFDRNPQGDKDYYPLGIDTAM 224 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++RI +G VG I +F THG S+TN+NHLISGDNKG AAY WE V G YL G+P F Sbjct 225 RVLRISQGGDNVGGIGWFPTHGASLTNKNHLISGDNKGAAAYFWEHDVAGVRYLDGKPGF 284 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGA-GI 301 +A F QTN GDMSPN+D L P P EF+NTR G Q A ATP+ + + Sbjct 285 VACFPQTNTGDMSPNLD--LKPGHGPTADEFENTRIIGERQVAAAREAFRKATPLASTTV 342 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQG-RNPFWD 359 D+R Y+D+ + +V G+YT DG+ RRT GA AG T++GP F +G RNP D Sbjct 343 DSRIMYLDMANQVVDGKYTSDGQVRRTAPACVGAAMAAGSTEDGPAIEIFTEGTRNPMID 402 Query 360 RLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHP--FVQEIVPVQLVRIGRLYLIGIPGE 417 L + + AQAPK +++P L + P +V ++ +Q++RIG +Y++G P E Sbjct 403 ALGGIDTPTPQWLSDAQAPKLVLVPVGL---LPPDGWVPHVLKIQIIRIGDVYVVGGPAE 459 Query 418 PTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 TIV+GLR+RR VA +G L +V+ GY NAY Y TTPEEY Q+YEGGSTLFGR L Sbjct 460 FTIVSGLRIRRTVAEELGVPLENVIFNGYANAYSSYCTTPEEYDAQQYEGGSTLFGRNTL 519 Query 478 CALMQTVAELAEAMRDGRPVTLGRRPRPT--------RELSWVRGAPADAGSFGAVIAEP 529 A Q A LA AM+ G V G PR RE + AP FG V+ +P Sbjct 520 PAYQQGFAALAAAMKAGADVPRGPAPRDLSGFQPGFGREFPF--DAPLPGRDFGDVVVQP 577 Query 530 SATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGR 589 + + G+ V FV+ P NDL R GTY EV RR+G W R ADDGDWAT +RW+R+G Sbjct 578 AGSVGAGEQVAVEFVTGHPKNDLHRRGTYFEVQRRDGDRWTRHADDGDWATKYRWRREGL 637 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 S I WDVP T G YRI H G ++ G + AF+ T+ EFTV Sbjct 638 NSSVARITWDVPAGTPSGTYRIQHFGNWKNPEGAVFAFTGTSAEFTV 684 >gi|312138151|ref|YP_004005487.1| ceramidase [Rhodococcus equi 103S] gi|311887490|emb|CBH46802.1| putative secreted ceramidase [Rhodococcus equi 103S] Length=685 Score = 497 bits (1279), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 294/647 (46%), Positives = 388/647 (60%), Gaps = 24/647 (3%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VG G++D+TG A+ GM+GY + DQR G+HQR R RA+VF D D R++ A+ Sbjct 48 VGVGLSDMTGPVAENGMMGYSQFDQRAEGLHQRTRVRAYVFADAD---DNRVVYTCADTC 104 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q V++ VL RLA +G+ Y+E+N ++TA H+HA GG Y+L T GF+P F Sbjct 105 MVFQAVHDAVLARLAARFGNLYTEKNVMLTAVHSHAACGGASQDYAYSLATLGFQPQVFD 164 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A VDG+VE++ AH ++A V+ EL AS+NRS +AFDRNP DK ++P +D Sbjct 165 AEVDGVVEAIVAAHDNLAAGTVAYGRSELKDASVNRSRAAFDRNPQGDKDYYPLGIDTAM 224 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++RI +G VG I +F THG S+TN+NHLISGDNKG AAY WE V G YL G+P F Sbjct 225 RVLRISQGGDNVGGIGWFPTHGASLTNKNHLISGDNKGAAAYFWEHDVAGVRYLDGKPGF 284 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGA-GI 301 +A F QTN GDMSPN+D L P P EF+NTR G Q A ATP+ + + Sbjct 285 VACFPQTNTGDMSPNLD--LKPGHGPTADEFENTRIIGERQVAAAREAFRKATPLASTTV 342 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQG-RNPFWD 359 D+R Y+D+ + +V G+YT DG+ RRT GA AG T++GP F +G RNP D Sbjct 343 DSRIMYLDMANQVVDGKYTSDGQVRRTAPACVGAAMAAGSTEDGPAIEIFTEGTRNPMID 402 Query 360 RLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHP--FVQEIVPVQLVRIGRLYLIGIPGE 417 L + A AQAPK +++P L + P +V ++ +Q++RIG +Y++G P E Sbjct 403 ALGGIDTPTPQWLADAQAPKLVLVPVGL---LPPDGWVPHVLKIQIIRIGDVYVVGGPAE 459 Query 418 PTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 TIV+GLR+RR VA +G L +V+ GY NAY Y TTPEEY Q+YEGGSTLFGR L Sbjct 460 FTIVSGLRIRRTVAEELGVPLENVIFNGYANAYSSYCTTPEEYDAQQYEGGSTLFGRNTL 519 Query 478 CALMQTVAELAEAMRDGRPVTLGRRPRPT--------RELSWVRGAPADAGSFGAVIAEP 529 A Q A LA AM+ G V G PR RE + AP FG V+ +P Sbjct 520 PAYQQGFAALAAAMKAGADVPRGPAPRDLSGFQPGFGREFPF--DAPLPGRDFGDVVVQP 577 Query 530 SATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGR 589 + + G+ V FV+ P NDL R GTY EV RR+G W R ADDGDWAT +RW+R+G Sbjct 578 AGSVGAGEQVAVEFVTGHPKNDLHRRGTYFEVQRRDGDRWTRHADDGDWATKYRWRREGL 637 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 S I WDVP T G YRI H G ++ G + AF+ T+ EFTV Sbjct 638 NSSVARITWDVPAGTPSGTYRIQHFGNWKNPEGAVFAFTGTSAEFTV 684 >gi|226304253|ref|YP_002764211.1| ceramidase [Rhodococcus erythropolis PR4] gi|226183368|dbj|BAH31472.1| probable ceramidase [Rhodococcus erythropolis PR4] Length=685 Score = 496 bits (1277), Expect = 5e-138, Method: Compositional matrix adjust. Identities = 286/646 (45%), Positives = 379/646 (59%), Gaps = 23/646 (3%) Query 2 LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAE 61 L VG GI+D+TG A+ GM+GY DQR G+HQR+R+RAF+F + G +R+ + + Sbjct 47 LQVGVGISDVTGPVAEVGMMGYSSFDQRAEGLHQRMRARAFIF----ESGGSRVAYVCVD 102 Query 62 LPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPAT 121 + Q+V++EVLRRLA +GD Y+E+N ++TA H+HA GG YNL GF Sbjct 103 NCMIFQSVHDEVLRRLAGRFGDIYAERNVMLTAIHSHAACGGASHNYAYNLAVLGFELQV 162 Query 122 FAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDP 181 F A V+G+VE++ AH ++AP V +L AS+NRS AFD NP DKA++P D Sbjct 163 FEAEVNGMVEAISAAHENLAPGTVRFGRSDLTDASVNRSRVAFDLNPEEDKAYYPGGNDH 222 Query 182 HTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQP 241 H ++RI RG +G I++FATH S+TN NHLISGDNKG AAY WE G YL G Sbjct 223 HMRVMRISRGSKDIGAINWFATHCASLTNENHLISGDNKGAAAYFWEHDDQGVRYLDGDT 282 Query 242 DFIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGAT-PIGA 299 FIAAF QTN GDMSPN+ L P P + EF+N R GL Q A T A+ + Sbjct 283 SFIAAFPQTNSGDMSPNLF--LEPGRGPTEDEFENARIIGLRQVAAARTAFDAASDTVTG 340 Query 300 GIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPF 357 G+D+R Y+D+ + +V G +TPDG E RT GA AG+ ++GP F +G RNP Sbjct 341 GVDSRIMYLDMANQVVSGRFTPDGREHRTAPAAIGAAMSAGSVEDGPAIPIFPEGTRNPM 400 Query 358 WDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHP--FVQEIVPVQLVRIGRLYLIGIP 415 D L + + AQAPK +V+P L + P +V ++ +Q++RIG+ Y++G P Sbjct 401 IDALGGMDAPVPQWLQDAQAPKLVVVPVGL---LPPGGWVPNVLKIQILRIGQFYIVGGP 457 Query 416 GEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRW 475 E TIV+GLR+RR VA +G L +V+ GY N+Y Y TTP+EY Q+YEGGST+FGR+ Sbjct 458 AEFTIVSGLRVRRTVAEELGVPLENVIFQGYANSYSSYCTTPQEYDSQQYEGGSTMFGRY 517 Query 476 ELCALMQTVAELAEAMRDGRPVTLGRRP------RPTRELSWVRGAPADAGSFGAVIAEP 529 L A Q A LA AMRDG G P +P+ P FG +P Sbjct 518 TLPAYQQGYAALAAAMRDGTEPPRGPAPADLSGFQPSFGPGVDFDEPLPGTQFGDATVQP 577 Query 530 SATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGR 589 T PG V FV+ P ND R GT+ E+ R G SW R+ADD DW+T W+R G Sbjct 578 GDT-SPGGQVAVEFVTGHPKNDTHRNGTFYEIQRNTGGSWTRVADDNDWSTKLHWRRVGS 636 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARDR-NGMLTAFSATTREF 634 GS V I WDVP DT G YR+ H G ++ R +G +T FS T EF Sbjct 637 NGSVVRITWDVPADTPAGTYRVQHFGASKARGSGAITPFSGVTAEF 682 >gi|229494547|ref|ZP_04388310.1| alkaline ceramidase [Rhodococcus erythropolis SK121] gi|229318909|gb|EEN84767.1| alkaline ceramidase [Rhodococcus erythropolis SK121] Length=685 Score = 496 bits (1277), Expect = 5e-138, Method: Compositional matrix adjust. Identities = 285/646 (45%), Positives = 379/646 (59%), Gaps = 23/646 (3%) Query 2 LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAE 61 L VG GI+D+TG A+ GM+GY DQR G+HQR+R+RAF+F + G +R+ + + Sbjct 47 LQVGVGISDVTGPVAEVGMMGYSSFDQRAEGLHQRMRARAFIF----ESGGSRVAYVCVD 102 Query 62 LPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPAT 121 + Q+V++EVLRRLA +GD Y+E+N ++TA H+HA GG YNL GF Sbjct 103 NCMIFQSVHDEVLRRLAGSFGDIYTERNVMLTAIHSHAACGGASHNYAYNLAVLGFELQV 162 Query 122 FAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDP 181 F A V+G+VE++ AH ++AP V +L AS+NRS AFD NP DKA++P D Sbjct 163 FEAEVNGMVEAISAAHENLAPGTVRFGRSDLTDASVNRSRVAFDLNPEEDKAYYPGGNDH 222 Query 182 HTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQP 241 H ++RI RG +G I++FATH S+TN NHLISGDNKG AAY WE G YL G Sbjct 223 HMRVMRISRGSKDIGAINWFATHCASLTNENHLISGDNKGAAAYFWEHDDQGVRYLDGDT 282 Query 242 DFIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGAT-PIGA 299 FIAAF QTN GDMSPN+ L P P + EF+N R GL Q A T A+ + Sbjct 283 SFIAAFPQTNSGDMSPNLF--LEPGRGPTEDEFENARIIGLRQVAAARTAFDAASDTVTG 340 Query 300 GIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPF 357 G+D+R Y+D+ + +V G +TPDG E RT GA AG+ ++GP F +G RNP Sbjct 341 GVDSRIMYLDMANQVVSGRFTPDGREHRTAPAAIGAAMSAGSVEDGPAIPIFPEGTRNPM 400 Query 358 WDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHP--FVQEIVPVQLVRIGRLYLIGIP 415 D L + + AQAPK +V+P L + P +V ++ +Q++RIG+ Y++G P Sbjct 401 IDALGGMDAPVPQWLQDAQAPKLVVVPVGL---LPPGGWVPNVLKIQILRIGQFYIVGGP 457 Query 416 GEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRW 475 E TIV+GLR+RR VA +G L +V+ GY N+Y Y TTP+EY Q+YEGGST+FGR+ Sbjct 458 AEFTIVSGLRVRRTVAEELGVPLENVIFQGYANSYSSYCTTPQEYDSQQYEGGSTMFGRY 517 Query 476 ELCALMQTVAELAEAMRDGRPVTLGRRP------RPTRELSWVRGAPADAGSFGAVIAEP 529 L A Q A LA AMRDG G P +P+ P FG +P Sbjct 518 TLPAYQQGYAALAAAMRDGTEPPRGPAPADLSGFQPSFGPGVDFDEPLPGTQFGDATVQP 577 Query 530 SATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGR 589 + PG V FV+ P ND R GT+ E+ R G SW R+ADD DW+T W+R G Sbjct 578 GDS-SPGAQVAVEFVTGHPKNDTHRNGTFYEIQRNTGGSWTRVADDNDWSTKLHWRRVGS 636 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARDR-NGMLTAFSATTREF 634 GS V I WDVP DT G YR+ H G ++ R +G +T FS T EF Sbjct 637 NGSVVRITWDVPADTPAGTYRVQHFGASKARGSGAITPFSGVTAEF 682 >gi|111021557|ref|YP_704529.1| hypothetical protein RHA1_ro04585 [Rhodococcus jostii RHA1] gi|110821087|gb|ABG96371.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=676 Score = 494 bits (1271), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 291/646 (46%), Positives = 384/646 (60%), Gaps = 21/646 (3%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 +G GI+D TG AD GM+GY +QR G+HQR R+RAFVF ++ G R++ + ++ Sbjct 38 IGVGISDATGPVADVGMMGYSSFEQRAEGLHQRTRARAFVF---AEPGRQRVVYVCVDVC 94 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V++ VL RLA+L+G Y+E+N ++TA H+HA GG YNL G F Sbjct 95 MIFQSVHDAVLARLAELHGGLYTERNVMLTAVHSHAACGGASHDYAYNLAVLGHNRQVFD 154 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A V GIVE++ AH +AP VS EL AS+NRS AF RNP D+ ++P +D Sbjct 155 AEVCGIVEAITAAHDSLAPGSVSYGRSELTDASVNRSRIAFGRNPSEDRDYYPLGIDTSM 214 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYL-AGQPD 242 ++RI +G VG I++F THG S+TN NHLISGDNKG AAY WE G YL +P Sbjct 215 RVLRITQGGRDVGAINWFPTHGASLTNTNHLISGDNKGAAAYFWEHDHEGVRYLDDDKPR 274 Query 243 FIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPI-GAG 300 F+AAF QTN GDMSPN+D L P P D EF+NTR G Q A T A+ I G Sbjct 275 FVAAFPQTNTGDMSPNLD--LRPGHGPTDDEFENTRIIGRRQVAAARTAWESASDILTGG 332 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQG-RNPFW 358 +D+R Y+D+ + V GE+TPDG RT GA AG T++GP F +G NP Sbjct 333 VDSRIMYLDMANQEVGGEFTPDGRTYRTSPACVGAAMSAGSTEDGPAIPIFPEGTTNPLV 392 Query 359 DRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHP--FVQEIVPVQLVRIGRLYLIGIPG 416 D L + + AQAPK +++ L + P +V ++ +Q++RIG +Y++G P Sbjct 393 DALGGMDAPIPQWLQDAQAPKLVLVAVGL---LPPDGWVPHVLKIQIIRIGGVYVVGGPA 449 Query 417 EPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE 476 E TIV+GLR+RR VA +G L +V+ GY N+Y Y TTP+EY Q+YEGGSTLFGR+ Sbjct 450 EFTIVSGLRIRRTVADRLGVPLENVIFQGYANSYASYCTTPQEYDAQQYEGGSTLFGRYT 509 Query 477 LCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPAD-----AGS-FGAVIAEPS 530 L A Q A LA+AMR GR V G PR + G D AG FG V+ EP+ Sbjct 510 LPAYQQGFAALADAMRTGRDVPRGPAPRDLSQFQPYAGPGVDHDEPPAGRVFGDVLTEPA 569 Query 531 ATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRA 590 A G+ V FV+ P ND RR GT+LE+ RR G WVR ADDGDW+T +RW R G Sbjct 570 AKVSAGEQVTVEFVTGHPRNDPRRRGTFLEIQRRGGDGWVRHADDGDWSTKYRWTRTGSN 629 Query 591 GSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 S I WDVP T G+YR+ H G +RD G +T+F+ T+ EF V Sbjct 630 RSVAQITWDVPAGTPAGRYRVQHFGNSRDAAGAITSFTGTSNEFEV 675 >gi|54022614|ref|YP_116856.1| hypothetical protein nfa6470 [Nocardia farcinica IFM 10152] gi|54014122|dbj|BAD55492.1| putative ceramidase [Nocardia farcinica IFM 10152] Length=697 Score = 491 bits (1263), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 299/644 (47%), Positives = 382/644 (60%), Gaps = 18/644 (2%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VG GI+DITG AA+CGM+GY + Q TAGIH R R+RAF+F + G AR++ VAE Sbjct 60 VGLGISDITGPAAECGMMGYSQFGQDTAGIHLRPRARAFIF----EAGAARVVFAVAENG 115 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q+V+ VL LA +GD Y+EQN L+T+TH+HA GG YNL+ GF+ + Sbjct 116 MIFQSVHRGVLLELARRFGDRYTEQNVLLTSTHSHATCGGASHDYAYNLSVLGFQQQVYD 175 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A V GIVE++ AH D++PA ++L EL+ AS+NRS AF+RNP D+A FP +DP Sbjct 176 AEVQGIVEAIVAAHEDLSPATLALGRAELHDASVNRSRVAFERNPAEDRAHFPGAIDPAV 235 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T + I +G VG I +FATH TSMTN+N LIS DNKG+AA+ E G YL G P+F Sbjct 236 TALSIRKGGREVGAITWFATHNTSMTNQNRLISSDNKGYAAFAHEHIEHGVRYLDGAPEF 295 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGID 302 IAAFAQTN GDMSPN++ L P P D EF NTR G Q + L+ A P+ + Sbjct 296 IAAFAQTNAGDMSPNLN--LRPGSGPTDDEFANTRIIGERQHAASKAALAQAAPVRGPVQ 353 Query 303 ARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHG--FRQG-RNPFW 358 + Y+DL + V G +TPDG+ RRT G +AG+ ++GPG G +G RNP Sbjct 354 SLLCYIDLADIAVDGRFTPDGQPRRTAPAAAGVSLIAGSVEDGPGLPGAPIPEGVRNPLI 413 Query 359 DRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEP 418 D L A AQAPK I P L + +V +VP+QLVRIG LYL GE Sbjct 414 DALGDPRRPAPSWLADAQAPKVIAAPLGLLPPVP-WVPNVVPIQLVRIGELYLAAAGGEF 472 Query 419 TIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 TIVAGLR+RR VA+ +G DL VL GY NAY YVTTPEEY Q+YEGGSTLFGR+ L Sbjct 473 TIVAGLRVRRAVAAALGVDLEQVLLQGYANAYHQYVTTPEEYDAQQYEGGSTLFGRYTLP 532 Query 479 ALMQTVAELAEAMRDGRPVTLGRRPRPTREL--SWVRGAPADAG----SFGAVIAEPSAT 532 A Q LA A+ G V G PR L + V D +FG V+ +P+ Sbjct 533 AYQQEFTRLATALATGGTVARGPAPRDVSHLQPNLVPAPGPDTALPDRTFGDVLVQPAPG 592 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGS 592 Y G+ V A FVSA P +D RR GT+LEV RR WVR+A++G+WA F W++ G A S Sbjct 593 YARGEQVVAEFVSAHPKHDPRRNGTFLEVQRRTADGWVRVANEGEWAVRFHWRKTGTATS 652 Query 593 HVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 WD+P D PG+YR VH +G + T EF + Sbjct 653 IARFTWDIPADAAPGRYRFVHFAGRLAPDGSRHPVTGVTDEFDI 696 >gi|323720893|gb|EGB29959.1| hypothetical protein TMMG_03376 [Mycobacterium tuberculosis CDC1551A] Length=301 Score = 490 bits (1261), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 240/240 (100%), Positives = 240/240 (100%), Gaps = 0/240 (0%) Query 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA Sbjct 1 MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVA 60 Query 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA Sbjct 61 ELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPA 120 Query 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD Sbjct 121 TFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVD 180 Query 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ Sbjct 181 PHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 >gi|319949468|ref|ZP_08023527.1| hydrolase [Dietzia cinnamea P4] gi|319436872|gb|EFV91933.1| hydrolase [Dietzia cinnamea P4] Length=693 Score = 481 bits (1238), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 285/652 (44%), Positives = 384/652 (59%), Gaps = 28/652 (4%) Query 2 LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAE 61 L VGRGI D+TGE GM GY ++Q + G+H R R+RAFVF D R L + AE Sbjct 52 LYVGRGIGDMTGEPLGAGMNGYADTEQLSVGLHLRQRARAFVFADSPSS--PRFLHVTAE 109 Query 62 LPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPAT 121 + L Q++ +EVLRRLA +G TY E N +ITATHTH PGG G+ + +L+ GFRP T Sbjct 110 IGLIFQSIQQEVLRRLAAEFGGTYHEGNVVITATHTHVAPGGTSGHPMVDLSMLGFRPVT 169 Query 122 FAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDP 181 F A V GIV++V AH D+AP+EV ++ G L A + RS +F+R+ P ++A FP+ +DP Sbjct 170 FEANVAGIVDAVRMAHHDLAPSEVGVTTGTLRDAGVQRSRGSFERDTPEERAHFPEGIDP 229 Query 182 HTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLA-GQ 240 + ++I RG GV+++FATH TSMT+ N + S DNKG+AA+HWER V G DYLA G Sbjct 230 RSQSLQITRGGQLAGVLNWFATHATSMTSHNRIASSDNKGYAAWHWEREVAGQDYLAGGT 289 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLS-GATPIG 298 P + AFAQTNPGD+SPN+D L P P E+ NTR G QF A Q+ P+G Sbjct 290 PALVTAFAQTNPGDVSPNLD--LEPGRGPTPDEWLNTRINGERQFAAARDQVDRDVRPLG 347 Query 299 AGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPG------FHGFRQ 352 GID R +VD+ +V VR E+T DG RT GA +G+ E G F + Sbjct 348 GGIDVRHVWVDMSAVEVRPEFTGDGRTHRTAVAALGASFASGSQEDGGGGDELPFAEGDR 407 Query 353 GRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARL-PNRIHPFVQEIVPVQLVRIGRLYL 411 G NP L+ + + A APK +++P L PN VQ + P LVR+G YL Sbjct 408 GGNPAVKALTDVV--IPAWLREAHAPKDVLLPVGLVPNA----VQRVYPFHLVRLGTHYL 461 Query 412 IGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTL 471 + EPT+VAGLRLRR +A+ +G V GY+N+Y HYVTTPEEY Q YEGG+T+ Sbjct 462 FTLGFEPTVVAGLRLRRTLAAELGVAEDYVTVQGYSNSYGHYVTTPEEYSAQNYEGGATI 521 Query 472 FGRWELCALMQTVAELAEAMRDGRPVTLGRRPR------PTREL-SWVRGAPADAGSFGA 524 FG W L A+ Q A+LA ++R G P+ G R P L + + PA +FG Sbjct 522 FGPWTLPAIQQIAADLARSIRAGTPLDPGTSERDLTGQIPVSPLGNPLVDTPAPLRNFGD 581 Query 525 VIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRW 584 V+ +P YR GQ V F PN+DLRRG TYL + RR+G W+R+ DDGDW+T + Sbjct 582 VLDQPLPEYRVGQRVLVRFCGTHPNSDLRRGDTYLAIERRDGGRWIRVHDDGDWSTMIVF 641 Query 585 QRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 + ++ + WD+P T G+YR+V+ + R +G L +R F V Sbjct 642 EGLLTV-TNALVTWDIPPGTPAGEYRVVYTASGRGFDGRLFPVRGQSRGFAV 692 >gi|333920233|ref|YP_004493814.1| hypothetical protein AS9A_2567 [Amycolicicoccus subflavus DQS3-9A1] gi|333482454|gb|AEF41014.1| hypothetical protein AS9A_2567 [Amycolicicoccus subflavus DQS3-9A1] Length=606 Score = 471 bits (1213), Expect = 1e-130, Method: Compositional matrix adjust. Identities = 281/619 (46%), Positives = 363/619 (59%), Gaps = 40/619 (6%) Query 3 SVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAEL 62 SVG GIAD+TG A GM+GY QRT GIH RLR+RAF+ DG R++ + A+L Sbjct 5 SVGCGIADVTGVAYGNGMMGYSMPQQRTGGIHLRLRARAFIV----DDGTTRVVFVCADL 60 Query 63 PLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATF 122 + V + VL L +G Y EQN L+TATHTHAGPGG+ +LLYNL GF TF Sbjct 61 GMIFDAVRQAVLVELGGKFGSLYGEQNVLLTATHTHAGPGGFSHHLLYNLAPLGFHEKTF 120 Query 123 AAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPH 182 A+V GIV +V +AH +AP +++ EL+ AS+NRS AFD NP D+ FP+ +DP Sbjct 121 GAVVTGIVAAVSNAHDAMAPGSLAVGQTELWDASVNRSRPAFDLNPLEDQREFPRAIDPA 180 Query 183 TTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPD 242 T++R +G VG I FFATHGTSMTN N LISGDNKG+AAY WE G Y A Sbjct 181 MTVLRFRQGSTDVGAISFFATHGTSMTNTNRLISGDNKGYAAYQWEHDHAGVRYRADTRP 240 Query 243 FIAAFAQTNPGDMSPNVDGPLSPEAPPDR-EFDNTRRTGLCQFEDAFTQLSGATPIGAGI 301 F+AAF QTN GDMSPN++ L P P R EF NT+ G QF A +GA P+ G+ Sbjct 241 FVAAFPQTNAGDMSPNLE--LKPGTGPTRDEFTNTQMIGGRQFRAALGAFNGARPLRGGV 298 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGT-DEGPGFHGFRQG-RNPFWD 359 D+R YVD+ V + YTPDG+ RT G +AG+ ++GPG G +G R PF Sbjct 299 DSRLQYVDMSDVAIDSTYTPDGKPHRTRSSAIGLPTLAGSVEDGPGI-GIPEGLRKPF-- 355 Query 360 RLSRAMYRLARPTAAAQAPKGIVMPA-RLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEP 418 A+ + +V+P+ RL + I+P+Q++R+G L+L+ P E Sbjct 356 --------------ASHDRRIVVLPSGRL-----GWTPNILPLQIMRLGTLHLVAGPAEF 396 Query 419 TIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 TIVAGLR+R VA+ + ++ DVL VGY+NAY YVTTPEEY Q+YEGGSTLFGR+ LC Sbjct 397 TIVAGLRIRTSVAAELRVNVEDVLLVGYSNAYSQYVTTPEEYDSQQYEGGSTLFGRYSLC 456 Query 479 ALMQTVAELAEAM--RDGRPVTLGR-RPRPTRELSWVRGAPADAGSFGAVIAEPSATYRP 535 A Q LA + R P + R PR VR + G++G V+ PS +YRP Sbjct 457 AYQQEFVRLARDLTSRAALPKSQDRGAPRNVLRARTVR--RRENGTYGRVLTAPSPSYRP 514 Query 536 GQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVS 595 G V A FV+A P + + Y++V SWV IADDGDW T + R+ R Sbjct 515 GATVVAEFVAAHPADAM--CPNYIDVEHHRDGSWVHIADDGDWETRVTFARRRRQ-LIAR 571 Query 596 IRWDVPGDTTPGQYRIVHH 614 W VP DT G YRIV+H Sbjct 572 AEWTVPEDTCAGTYRIVYH 590 >gi|262201941|ref|YP_003273149.1| ceramidase [Gordonia bronchialis DSM 43247] gi|262085288|gb|ACY21256.1| Ceramidase [Gordonia bronchialis DSM 43247] Length=682 Score = 446 bits (1147), Expect = 5e-123, Method: Compositional matrix adjust. Identities = 273/653 (42%), Positives = 374/653 (58%), Gaps = 38/653 (5%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 VG GIAD+TG A GM+GY ++DQ G+ QR +RA++ D++ +R++ + A++ Sbjct 45 VGCGIADMTGAVAGQGMMGYSEADQVAEGLLQRCWARAYIVVDEAIG--SRVVFVTADIA 102 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 Q+ + ++ RL +G Y+E+N + ATH+HA GG Y+L GF+ ++ Sbjct 103 CLFQSHHMGLMPRLRARFGSLYTERNVNLNATHSHASCGGTAWDYAYSLAAYGFKKNSYE 162 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 A VDG+ ++ AH ++AP +S+ GEL+ AS NRS AFD NP +++ FP +DP Sbjct 163 AEVDGLFAAIVRAHENLAPGSISIGRGELHDASANRSKVAFDLNPASERRHFPSAIDPTV 222 Query 184 TLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 T++R +G +G I +F+THGTS+T+RN LI+GDNKG+A+Y WE T QP F Sbjct 223 TVLRFRQGGNDIGAITWFSTHGTSLTDRNRLIAGDNKGYASYRWEST---------QPGF 273 Query 244 IAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLC---QFEDAFTQLSGATPIG-A 299 +AAF QTN GDM+PN++ L P FDN R + Q+ GA + Sbjct 274 VAAFPQTNSGDMTPNLN--LIKMRPSGPTFDNRRNCAIIGERQYLAGRNAFDGARAMSRG 331 Query 300 GIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWD 359 G+D+ YVD+ +V + YTP+G RT M GA A A + E + + + Sbjct 332 GVDSIVRYVDMSAVSIDAAYTPEGRPARTTPAMMGAAAAATSTEDNYYSQLPFLQEGVTN 391 Query 360 RLSRAMYRLARPTAA-----AQAPKGIVMP-ARLPNRIHPFVQEIVPVQLVRIGRLYLIG 413 L A RP A QAPK I+ P LP P++ ++VP+Q++RIG L L+ Sbjct 392 PLVAAFGGDRRPPIAPWMRDMQAPKLILFPLGLLPP--SPWIPQVVPLQIMRIGELVLVA 449 Query 414 IPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFG 473 +P E TIVAGLRLR++VA + DL DVL GY+NAY YVTTPEEY Q+YEGG T FG Sbjct 450 VPAEVTIVAGLRLRQVVADALRVDLDDVLVQGYSNAYTQYVTTPEEYDAQQYEGGETQFG 509 Query 474 RWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELS----WVRGAPAD---AG-SFGAV 525 RW L A MQ A LA AM GRP LGR P P + + + P D AG +G V Sbjct 510 RWTLSAYMQEFARLAAAMATGRP--LGRGPAPLDKSAVQPDLLPAVPPDRPVAGRRYGDV 567 Query 526 IAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQ 585 + P + YR GQ V FV A PNND R G TYLE+ RRE W IADD DW+T FRW Sbjct 568 LVSPRSRYRAGQQVAVTFVGAHPNNDFRHGRTYLEIQRRERTGWHTIADDNDWSTEFRWS 627 Query 586 RQGRA--GSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTV 636 R + SH+ I W P T+ G YR+ +HG +RD G++ S T+R F V Sbjct 628 RPAGSSDASHIRITWTPPPGTS-GTYRVRYHGNSRDARGVVREISGTSRAFAV 679 >gi|115374581|ref|ZP_01461861.1| neutral/alkaline nonlysosomal ceramidase superfamily [Stigmatella aurantiaca DW4/3-1] gi|310823754|ref|YP_003956112.1| alkaline ceramidase [Stigmatella aurantiaca DW4/3-1] gi|115368451|gb|EAU67406.1| neutral/alkaline nonlysosomal ceramidase superfamily [Stigmatella aurantiaca DW4/3-1] gi|309396826|gb|ADO74285.1| Alkaline ceramidase [Stigmatella aurantiaca DW4/3-1] Length=689 Score = 444 bits (1142), Expect = 2e-122, Method: Compositional matrix adjust. Identities = 264/663 (40%), Positives = 377/663 (57%), Gaps = 52/663 (7%) Query 2 LSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAE 61 VG GI DITG AA+ GM+GY DQ+TAGIHQRLR+RAFV S R+ + A+ Sbjct 50 FQVGSGIYDITGPAAELGMMGYAMIDQKTAGIHQRLRARAFVVA--SPCNGKRVAFVSAD 107 Query 62 LPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPAT 121 Q V ++V+ RL +G+ Y+++N +++ATHTH+GPGG+ Y LYNLT G+ Sbjct 108 AGQIFQGVRQQVVERLKARFGNLYTDENVVLSATHTHSGPGGFSHYALYNLTILGYDRQN 167 Query 122 FAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDP 181 F AIVDGI +++ AH ++ P V ++ G+L GA+INRSP A+ RNP A++ P D Sbjct 168 FEAIVDGIFQAIVQAHINLVPGNVRITSGDLLGATINRSPGAYLRNPAAERGQSPYDTDK 227 Query 182 HTTLVRIDRGE-ATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQ 240 TL+++ + A VG+I++FA HGTSM N N LISGDNKG+A+Y +E+ G +YLA + Sbjct 228 RMTLLKLQGADGAEVGLINWFAVHGTSMGNDNRLISGDNKGYASYLFEKD-KGTNYLASK 286 Query 241 PDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGAT-PIGA 299 F+AAFAQ+N GD++PN+ G + D F++T +G Q+ A GA+ P+ Sbjct 287 T-FVAAFAQSNEGDVTPNILGGTNGGGAND--FESTELSGRKQYVLAKQLYDGASQPLVG 343 Query 300 GIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHG----FRQGRN 355 +D R YV + V V +YT DG R T G +AG ++GPGF Q RN Sbjct 344 AVDYRHAYVKMDEVSVAPKYT-DGVWRSTCEAAIGVSMLAGAEDGPGFGSEGATCEQVRN 402 Query 356 PFWDRLSRAMYRLARPTAAAQAPKGIV--MPARLPNRIHPFVQEIVPVQLVRIGRLYLIG 413 W + + T + Q K +V M +P +P+ E++P+Q+V +G L L+ Sbjct 403 -IWSEFTCGL-----TTTSCQGEKPVVLEMGTMVP---YPWTPEVLPLQVVTLGNLALVA 453 Query 414 IPGEPTIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLF 472 +P E T +AG RLR+ V A + + V+ G +NAY Y+ T EEY +Q YEG ST F Sbjct 454 VPFEMTTMAGRRLRQTVLAQLAPVGVDQVVIAGLSNAYAGYLVTREEYAKQDYEGASTHF 513 Query 473 GRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTR--------------ELSWVRGAPAD 518 G W L A+ Q LA A+R G PV G PR R +L WV Sbjct 514 GPWTLAAVQQETERLASALRAGTPVAAGIAPRDLRNEQTSLQTGVVFDDKLLWVE----- 568 Query 519 AGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDW 578 FG V+ + +A+Y GQ V F P N+LRR G++L+V R+ G++W+ + D DW Sbjct 569 ---FGGVVTQANASYTRGQTVSVKFWGGHPKNNLRRQGSFLQVQRKSGSTWIPVLYDWDW 625 Query 579 ATSFRWQRQG----RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTRE 633 T +RW+R A SHV+I W +P PG YRI H G + +G++ ++ +RE Sbjct 626 ETKYRWERNNCVPTLACSHVTIEWAIPSTAVPGTYRIRHDGDWKSGWDGVIRPYTGYSRE 685 Query 634 FTV 636 FTV Sbjct 686 FTV 688 >gi|6594292|dbj|BAA88409.1| alkaline ceramidase [Pseudomonas aeruginosa] Length=670 Score = 431 bits (1107), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 266/649 (41%), Positives = 368/649 (57%), Gaps = 30/649 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 TFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPT 419 L + + + QA K I+ + +P+ ++P+Q+ RIG+L L+G P E T Sbjct 379 LGGLLTGVPPQELVQCQAEKTILADTG-NKKPYPWTPTVLPIQMFRIGQLELLGAPAEFT 437 Query 420 IVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 ++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 438 VMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQA 497 Query 479 ALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSAT 532 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P + Sbjct 498 AYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRES 557 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQGR 589 YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 558 YRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVGI 617 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 618 SASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|218893188|ref|YP_002442057.1| alkaline ceramidase [Pseudomonas aeruginosa LESB58] gi|218773416|emb|CAW29228.1| alkaline ceramidase [Pseudomonas aeruginosa LESB58] Length=670 Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 268/650 (42%), Positives = 370/650 (57%), Gaps = 32/650 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 379 LGGLLTGVPPQELVQCQAEKTIL--ADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEF 436 Query 419 TIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 437 TVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQ 496 Query 478 CALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSA 531 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P Sbjct 497 AAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRE 556 Query 532 TYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQG 588 +YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 557 SYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVG 616 Query 589 RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 617 ISASKATINWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|222446995|pdb|2ZXC|A Chain A, Seramidase Complexed With C2 gi|222446996|pdb|2ZXC|B Chain B, Seramidase Complexed With C2 gi|224510545|pdb|2ZWS|A Chain A, Crystal Structure Analysis Of Neutral Ceramidase From Pseudomonas Aeruginosa Length=646 Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 268/650 (42%), Positives = 370/650 (57%), Gaps = 32/650 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 8 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 65 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 66 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 125 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 126 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 183 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 184 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 237 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 238 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 295 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 296 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 354 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 355 LGGLLTGVPPQELVQCQAEKTIL--ADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEF 412 Query 419 TIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 413 TVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQ 472 Query 478 CALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSA 531 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P Sbjct 473 AAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRE 532 Query 532 TYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQG 588 +YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 533 SYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVG 592 Query 589 RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 593 ISASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 642 >gi|254239197|ref|ZP_04932520.1| conserved hypothetical protein [Pseudomonas aeruginosa C3719] gi|126171128|gb|EAZ56639.1| conserved hypothetical protein [Pseudomonas aeruginosa C3719] Length=670 Score = 429 bits (1104), Expect = 6e-118, Method: Compositional matrix adjust. Identities = 268/650 (42%), Positives = 369/650 (57%), Gaps = 32/650 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLNVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 LAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 379 LGGLLTGVPPQELVQCQAEKTIL--ADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEF 436 Query 419 TIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 437 TVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQ 496 Query 478 CALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSA 531 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P Sbjct 497 AAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRE 556 Query 532 TYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQG 588 +YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 557 SYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVG 616 Query 589 RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 617 ISASKATINWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|108760215|ref|YP_628881.1| alkaline ceramidase [Myxococcus xanthus DK 1622] gi|108464095|gb|ABF89280.1| alkaline ceramidase [Myxococcus xanthus DK 1622] Length=686 Score = 429 bits (1103), Expect = 7e-118, Method: Compositional matrix adjust. Identities = 275/652 (43%), Positives = 366/652 (57%), Gaps = 37/652 (5%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 +G G ADITG AA+ GM+GYG +Q+T GIHQRL SRAFV S R+ + A+L Sbjct 52 LGAGSADITGPAAEVGMMGYGMLEQQTTGIHQRLHSRAFVIA--SPCNGKRVAFVSADLG 109 Query 64 LPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFA 123 + Q V ++V+ RL YGD Y++ N L++ATHTH+GPGGY Y LYNLTT GF P F Sbjct 110 MVFQAVKQQVVERLRARYGDLYTDDNVLLSATHTHSGPGGYSHYTLYNLTTLGFSPQNFE 169 Query 124 AIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHT 183 AIV GIV S+ AH +A + LS GEL+GAS NRSP+A+ NP ++A + VD Sbjct 170 AIVSGIVASIVRAHERLAEGTLRLSSGELFGASRNRSPNAYLLNPAEERARYAHDVDTRM 229 Query 184 TLVRIDRGEAT-VGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPD 242 TL+R+ R + T +G+I++FA H TSM N N LISGDNKG A+Y E+ G D Sbjct 230 TLLRLTRADGTDMGLINWFAVHATSMGNGNTLISGDNKGLASYLAEQAQGAGD------T 283 Query 243 FIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGA-TPIGAGI 301 F+AAFA N GD++PN+ G D F++T +G Q++ A + A TP+ G+ Sbjct 284 FVAAFANANEGDVTPNILGGTHGGGAND--FEDTDLSGRKQYDFAAKLWAEAKTPLTGGV 341 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFH----GFRQGRNPF 357 D R YV + +V V + DG R T G +AG ++GPG G+N Sbjct 342 DYRHVYVKMDAVDVAPAFA-DGAPRTTCPAAIGVSMLAGAEDGPGVGVEGVTCAAGQNA- 399 Query 358 WDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGE 417 W + S ++ T QA K IV+ R P+ E++P+QLV IG L L+ +P E Sbjct 400 WGQFSCSL-----ATTPCQAEKPIVLEMG-SMRPFPWTPEVLPLQLVTIGNLALVAVPFE 453 Query 418 PTIVAGLRLRRMVASIVG-ADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE 476 T +AG RLR V + + A + DV+ G +NAY YV T EEY Q YEG ST FG W Sbjct 454 LTTMAGRRLRDTVETALAPAGVTDVVIAGLSNAYSGYVATREEYARQDYEGASTHFGPWT 513 Query 477 LCALMQTVAELAEAMRDGRPVTLGRRPRPTR--ELSWVRGAPADAG----SFGAVIAEPS 530 L AL Q LA ++RDG V G PR R +LS G D FG V+ + Sbjct 514 LAALQQNFHLLATSLRDGAGVPPGPTPRDLRKEQLSLQPGVVFDDKLLWVDFGEVVTDAR 573 Query 531 ATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRRE-GASWVRIADDGDWATSFRWQRQG- 588 TY G A F P NDLR GT+L V RRE +W +A D D AT ++W+R+ Sbjct 574 PTYSRGDTASATFWGGHPKNDLRLEGTFLRVQRREPDGTWTDVATDADPATRYQWRRENC 633 Query 589 ---RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTV 636 A SHV++ W +P DT PG YR+VH G + +G + +S +R FTV Sbjct 634 VPTLACSHVTVTWGIPDDTVPGTYRLVHEGNWKSGWDGNVRPYSGASRTFTV 685 >gi|116048768|ref|YP_792432.1| hypothetical protein PA14_53340 [Pseudomonas aeruginosa UCBPP-PA14] gi|115583989|gb|ABJ10004.1| alkaline ceramidase [Pseudomonas aeruginosa UCBPP-PA14] Length=670 Score = 429 bits (1103), Expect = 8e-118, Method: Compositional matrix adjust. Identities = 266/649 (41%), Positives = 368/649 (57%), Gaps = 30/649 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRRAGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLDEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPT 419 L + + + QA K I+ + +P+ ++P+Q+ RIG+L L+G P E T Sbjct 379 LGGLLTGVPPQELVQCQAEKTILADTG-NKKPYPWTPTVLPIQMFRIGQLELLGAPAEFT 437 Query 420 IVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 ++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 438 VMAGVRIRRAVQAASEAAGIRHVIFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQA 497 Query 479 ALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSAT 532 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P + Sbjct 498 AYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRES 557 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQGR 589 YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 558 YRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWYTQYRWERVGI 617 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 618 SASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|313105722|ref|ZP_07791985.1| alkaline ceramidase [Pseudomonas aeruginosa 39016] gi|310878487|gb|EFQ37081.1| alkaline ceramidase [Pseudomonas aeruginosa 39016] Length=661 Score = 429 bits (1102), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 266/649 (41%), Positives = 367/649 (57%), Gaps = 30/649 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 23 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 80 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 81 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 140 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 141 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 198 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 199 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 252 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 253 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 310 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 311 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLDEGNNPFLSA 369 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPT 419 L + + + QA K I+ + +P+ ++P+Q+ RIG+L L+G P E T Sbjct 370 LGGLLTGVPPQELVQCQAEKTILADTG-NKKPYPWTPTVLPIQMFRIGQLELLGAPAEFT 428 Query 420 IVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 ++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 429 VMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQA 488 Query 479 ALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSAT 532 A Q ++A A+R+ PV T P +++ G AD SFG V+ +P + Sbjct 489 AYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNLQTGVVADDPYIGKSFGDVLQQPRES 548 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQGR 589 YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 549 YRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVGI 608 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 609 SASKATINWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 657 >gi|107100302|ref|ZP_01364220.1| hypothetical protein PaerPA_01001327 [Pseudomonas aeruginosa PACS2] Length=670 Score = 428 bits (1101), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 268/650 (42%), Positives = 369/650 (57%), Gaps = 32/650 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 379 LGGLLTGVPPQELVQCQAEKTIL--ADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEF 436 Query 419 TIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 437 TVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQ 496 Query 478 CALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSA 531 A Q ++A A+R+ PV T P +++ G AD SFG V+ +P Sbjct 497 AAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNLQTGVVADDPYIGKSFGDVLQQPRE 556 Query 532 TYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQG 588 +YR G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 557 SYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKKTPVTVATDNDWDTQYRWERVG 616 Query 589 RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 617 ISASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|296390803|ref|ZP_06880278.1| alkaline ceramidase [Pseudomonas aeruginosa PAb1] gi|334843963|gb|EGM22544.1| alkaline ceramidase [Pseudomonas aeruginosa 152504] Length=670 Score = 428 bits (1101), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 265/649 (41%), Positives = 367/649 (57%), Gaps = 30/649 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPT 419 L + + + QA K I+ + +P+ ++P+Q+ RIG+L L+G P E T Sbjct 379 LGGLLTGVPPQELVQCQAEKTILADTG-NKKPYPWTPTVLPIQMFRIGQLELLGAPAEFT 437 Query 420 IVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELC 478 ++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 438 VMAGVRIRRAVQAASEAAGIRHVIFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQA 497 Query 479 ALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSAT 532 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P + Sbjct 498 AYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRES 557 Query 533 YRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQGR 589 Y G V FV+ P NDLR T+LEVV ++G V +A D DW T +RW+R G Sbjct 558 YHIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPVTVATDNDWDTQYRWERVGI 617 Query 590 AGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 618 SASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|330802030|ref|XP_003289024.1| hypothetical protein DICPUDRAFT_94802 [Dictyostelium purpureum] gi|325080903|gb|EGC34439.1| hypothetical protein DICPUDRAFT_94802 [Dictyostelium purpureum] Length=689 Score = 426 bits (1095), Expect = 7e-117, Method: Compositional matrix adjust. Identities = 247/674 (37%), Positives = 354/674 (53%), Gaps = 45/674 (6%) Query 4 VGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELP 63 +G GI DITG AA+ GM+GY Q T G+H RLR+RAFVF D + + R + + + Sbjct 18 IGTGIYDITGPAAETGMMGYAMPGQITGGLHFRLRARAFVFVDSNGN---RAVYVSTDSC 74 Query 64 LPMQNVNEEVLRRLADLYGDT-YSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATF 122 + Q V +V++ L ++G+ YS +N L++ THTH+GPGGY Y LY +TT GF F Sbjct 75 MIFQAVKIKVIQDLQAIFGENVYSHENVLLSGTHTHSGPGGYSMYALYGITTLGFYEDNF 134 Query 123 AAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPH 182 IVDGIV+++ AH VAPA + GEL ++INRSP+A+ NP +KA + VD + Sbjct 135 NTIVDGIVQAIVRAHKSVAPARMLAQQGELLESNINRSPTAYQNNPEEEKALYDYDVDKN 194 Query 183 TTLVRI-DRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQP 241 T++RI D V + FFA H TSM N NHLISGDNKG+A+Y WE+ G L GQ Sbjct 195 MTVIRIEDLNGNPVAAMSFFAVHCTSMNNTNHLISGDNKGYASYMWEKYQNGNSTLPGQG 254 Query 242 DFIAAFAQTNPGDMSPNVDGPLSPEAPPDRE-----------------------FDNTRR 278 FIA+F Q+N GD+SPN G P+ P + F++T+ Sbjct 255 PFIASFGQSNEGDVSPNTKGAFCPDGTPCVDSSSTCNGKNEGCKAIGPGKNGDMFESTQI 314 Query 279 TGLCQFEDAFTQLSGAT-PIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGA 337 G QF+ A A+ P+ I R ++V + ++ V+ + E T R G Sbjct 315 IGTNQFKKALELFENASIPVQGPIQYRHSWVQMTNISVQAPFNNGVEGATTCRAAMGYSF 374 Query 338 MAGTDEGPGFHGFRQGRNP-----FWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIH 392 AGT +GPG F QG N FW+ +S+ + Q+PK I++ L + + Sbjct 375 AAGTTDGPGAFDFTQGDNSTSGNIFWNFISKFIAVPTEDQKQCQSPKPILIDVGL-TKPY 433 Query 393 PFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLAD--VLCVGYTNAY 450 P+ +++PVQ++ IG++ L+ +PGE T ++G RLR V ++G + D VL G N Y Sbjct 434 PWTPDVLPVQIITIGQIVLVAVPGEFTTMSGRRLRNTVREVIGQSIQDPIVLVAGLANTY 493 Query 451 IHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELS 510 Y+ T EEY QRYEG ST+FG L Q A+LA+++ DG V G PR + Sbjct 494 SGYIATYEEYETQRYEGASTIFGPHTLGGYQQEFAKLAQSIVDGTEVDPGTFPRNLTGHT 553 Query 511 WVRGAPA------DAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRR 564 P FG + + +Y G VF A P N+ ++L V + Sbjct 554 LFFLPPVIFDEAPSGDDFGKIYTDAQESYSVGSQASVVFYGANPRNNFMIESSFLTVDQY 613 Query 565 EGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDR--NG 622 WV + +DGDW T F W+ A S ++I W++ T PG YRI H G A+ + Sbjct 614 VNNQWVTVLNDGDWDTKFIWKMHNLAQSLITIEWNIDPSTQPGTYRITHTGYAKKDPISK 673 Query 623 MLTAFSATTREFTV 636 LT + +R FTV Sbjct 674 DLTQYLGVSRTFTV 687 >gi|15596042|ref|NP_249536.1| hypothetical protein PA0845 [Pseudomonas aeruginosa PAO1] gi|81622531|sp|Q9I596.1|NCASE_PSEAE RecName: Full=Neutral ceramidase; Short=N-CDase; Short=NCDase; AltName: Full=Acylsphingosine deacylase; AltName: Full=N-acylsphingosine amidohydrolase; Flags: Precursor gi|9946741|gb|AAG04234.1|AE004519_5 conserved hypothetical protein [Pseudomonas aeruginosa PAO1] gi|15485644|emb|CAC67511.1| ceramide-hydrolysing enzyme [Pseudomonas aeruginosa] Length=670 Score = 424 bits (1091), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 265/650 (41%), Positives = 368/650 (57%), Gaps = 32/650 (4%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV S+E A A + P + GEL A+ NRS + +NP D + +DP + Sbjct 150 IVDGIVRSIERAQARLQPGRLFYGSGELRNANRNRSLLSHLKNP--DIVGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN NHLIS DNKG+A+YHWE V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDV------SRKSGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAG-I 301 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ A G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGEL 319 Query 302 DARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWDR 360 D+RF +VD + +R E+T DG+ R+ G AG T++GPG G +G NPF Sbjct 320 DSRFRFVDFTRLPIRPEFT-DGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSA 378 Query 361 LSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGEP 418 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 379 LGGLLTGVPPQELVQCQAEKTIL--ADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEF 436 Query 419 TIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWEL 477 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 437 TVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQ 496 Query 478 CALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPSA 531 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P Sbjct 497 AAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRE 556 Query 532 TYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASWVR-IADDGDWATSFRWQRQG 588 +YR G V FV+ P NDLR T+LEVV ++G +A D DW T +RW+R G Sbjct 557 SYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPETVATDNDWDTQYRWERVG 616 Query 589 RAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 + S +I W +P T PG Y I H+G A++ ++ +TR F V+ Sbjct 617 ISASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVL 666 >gi|152984039|ref|YP_001350019.1| hypothetical protein PSPA7_4675 [Pseudomonas aeruginosa PA7] gi|150959197|gb|ABR81222.1| conserved hypothetical protein [Pseudomonas aeruginosa PA7] Length=670 Score = 421 bits (1082), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 264/651 (41%), Positives = 370/651 (57%), Gaps = 34/651 (5%) Query 5 GRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPL 64 G G ADITGEAA+ GM+GY +Q+TAGIH R +RAFV + + RL+ + +L + Sbjct 32 GLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEPASG--RRLVYVNTDLGM 89 Query 65 PMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAA 124 Q V+ +VL RL Y Y E N ++ ATHTH+GPGG+ Y +YNL+ GF+ TF A Sbjct 90 IFQAVHLKVLARLKAKYPGIYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFDA 149 Query 125 IVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTT 184 IVDGIV ++E A A + P + GEL AS NRS + +NP D A + +DP + Sbjct 150 IVDGIVRAIERAQARLQPGRLFYGSGELRNASRNRSLLSHLKNP--DIAGYEDGIDPQMS 207 Query 185 LVR-IDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDF 243 ++ +D G I +F H TSMTN N LIS DNKG+A+YHWER V + + F Sbjct 208 VLSFVDANGELAGAISWFPVHSTSMTNANRLISPDNKGYASYHWERDV------SRKAGF 261 Query 244 IAAFAQTNPGDMSPNVDGPLSP-EAPPDREFDNTRRTGLCQFEDAFTQLSGAT--PIGAG 300 +AAFAQTN G++SPN++ L P P D EFDNTR GL QF A+ Q++G + Sbjct 262 VAAFAQTNAGNLSPNLN--LKPGSGPFDNEFDNTREIGLRQFAKAY-QIAGENQEEVLGE 318 Query 301 IDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAG-TDEGPGFHGFRQGRNPFWD 359 +D+RF +VD + +R E+T DG+ + G AG T++GPG G +G NPF Sbjct 319 LDSRFRFVDFTRLPIRPEFT-DGQPHQLCSAAIGTSLAAGSTEDGPGPLGLEEGNNPFLS 377 Query 360 RLSRAMYRL-ARPTAAAQAPKGIVMPARLPNRI-HPFVQEIVPVQLVRIGRLYLIGIPGE 417 L + + + QA K I+ A N+ +P+ ++P+Q+ RIG+L L+G P E Sbjct 378 ALGGLLTGVPPKELVQCQAEKTIL--ADTGNKQPYPWTPTVLPIQMFRIGQLELLGAPAE 435 Query 418 PTIVAGLRLRRMV-ASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWE 476 T++AG+R+RR V A+ A + V+ GY NAY YVTT EEY Q YEGGSTL+G W Sbjct 436 FTVMAGVRIRRAVQAASEAAGIRHVIFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWT 495 Query 477 LCALMQTVAELAEAMRDGRPV-TLGRRPR-PTRELSWVRGAPAD----AGSFGAVIAEPS 530 A Q ++A A+R+ PV T P ++++ G AD SFG V+ +P Sbjct 496 QAAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGRSFGDVLQQPR 555 Query 531 ATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVR--REGASW-VRIADDGDWATSFRWQRQ 587 +YR G V FV+ P NDLR T+LEVV ++G + IA D DW T + W+R Sbjct 556 ESYRIGDKVTVTFVTGHPKNDLRTEKTFLEVVYIGKDGKQTPMTIATDNDWDTQYHWERV 615 Query 588 GRAGSHVSIRWDVPGDTTPGQYRIVHHGTARD-RNGMLTAFSATTREFTVV 637 G + S +I W +P T PG Y I H+G ++ ++ +TR F V+ Sbjct 616 GISASKATISWTIPPGTEPGHYYIRHYGNKKNFWTQKISEIGGSTRSFEVL 666 Lambda K H 0.320 0.137 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1471207339360 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40