BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0691c
Length=198
Score E
Sequences producing significant alignments: (Bits) Value
gi|15607831|ref|NP_215205.1| transcriptional regulatory protein ... 405 2e-111
gi|289756779|ref|ZP_06516157.1| transcriptional regulatory prote... 404 4e-111
gi|339293721|gb|AEJ45832.1| transcriptional regulator [Mycobacte... 404 5e-111
gi|297633189|ref|ZP_06950969.1| transcriptional regulator [Mycob... 402 1e-110
gi|340625710|ref|YP_004744162.1| putative transcriptional regula... 400 5e-110
gi|240167692|ref|ZP_04746351.1| transcriptional regulator [Mycob... 327 5e-88
gi|254822797|ref|ZP_05227798.1| hypothetical protein MintA_22899... 322 3e-86
gi|41410249|ref|NP_963085.1| hypothetical protein MAP4151c [Myco... 317 5e-85
gi|118463601|ref|YP_883616.1| TetR family transcriptional regula... 317 8e-85
gi|336460678|gb|EGO39569.1| mycofactocin system transcriptional ... 317 8e-85
gi|118616555|ref|YP_904887.1| transcriptional regulator [Mycobac... 314 5e-84
gi|342861780|ref|ZP_08718425.1| hypothetical protein MCOL_22940 ... 313 6e-84
gi|296168545|ref|ZP_06850349.1| TetR family transcriptional regu... 310 9e-83
gi|333991991|ref|YP_004524605.1| transcriptional regulator [Myco... 285 2e-75
gi|108797971|ref|YP_638168.1| TetR family transcriptional regula... 270 9e-71
gi|118472856|ref|YP_885803.1| transcriptional regulatory protein... 267 6e-70
gi|120402305|ref|YP_952134.1| TetR family transcriptional regula... 259 1e-67
gi|145225638|ref|YP_001136316.1| TetR family transcriptional reg... 253 1e-65
gi|111023033|ref|YP_706005.1| AcrR family transcriptional regula... 214 4e-54
gi|158430737|pdb|2RAE|A Chain A, Crystal Structure Of A TetrACRR... 214 5e-54
gi|226365537|ref|YP_002783320.1| TetR family transcriptional reg... 214 7e-54
gi|226305285|ref|YP_002765243.1| TetR family transcriptional reg... 213 9e-54
gi|229490652|ref|ZP_04384490.1| transcriptional regulator, AcrR ... 213 1e-53
gi|169630916|ref|YP_001704565.1| transcriptional regulatory prot... 212 2e-53
gi|3873400|gb|AAC77476.1| unknown [Rhodococcus erythropolis] 211 5e-53
gi|312140962|ref|YP_004008298.1| tetr family transcriptional reg... 199 3e-49
gi|262203645|ref|YP_003274853.1| TetR family transcriptional reg... 190 9e-47
gi|343927804|ref|ZP_08767272.1| putative TetR family transcripti... 187 7e-46
gi|326384863|ref|ZP_08206538.1| regulatory protein TetR [Gordoni... 182 2e-44
gi|336178663|ref|YP_004584038.1| regulatory protein TetR [Franki... 171 5e-41
gi|324999705|ref|ZP_08120817.1| TetR family transcriptional regu... 167 8e-40
gi|111223716|ref|YP_714510.1| TetR family transcriptional regula... 166 2e-39
gi|312198474|ref|YP_004018535.1| TetR family transcriptional reg... 162 3e-38
gi|333922025|ref|YP_004495606.1| TetR family transcriptional reg... 161 4e-38
gi|331694457|ref|YP_004330696.1| TetR family transcriptional reg... 160 1e-37
gi|319950928|ref|ZP_08024804.1| regulatory protein TetR [Dietzia... 155 3e-36
gi|258651019|ref|YP_003200175.1| TetR family transcriptional reg... 151 5e-35
gi|288919778|ref|ZP_06414103.1| transcriptional regulator, TetR ... 149 2e-34
gi|258652559|ref|YP_003201715.1| TetR family transcriptional reg... 143 2e-32
gi|158315008|ref|YP_001507516.1| TetR family transcriptional reg... 142 2e-32
gi|269126599|ref|YP_003299969.1| TetR family transcriptional reg... 139 2e-31
gi|288918285|ref|ZP_06412639.1| transcriptional regulator, TetR ... 128 4e-28
gi|158315129|ref|YP_001507637.1| TetR family transcriptional reg... 112 3e-23
gi|284993286|ref|YP_003411841.1| TetR family transcriptional reg... 111 4e-23
gi|302529485|ref|ZP_07281827.1| transcriptional regulator [Strep... 107 9e-22
gi|54025179|ref|YP_119421.1| putative transcriptional regulator ... 98.6 4e-19
gi|50954607|ref|YP_061895.1| TetR family transcriptional regulat... 90.5 1e-16
gi|152968261|ref|YP_001364045.1| TetR family transcriptional reg... 86.7 2e-15
gi|330466754|ref|YP_004404497.1| putative transcriptional regula... 78.6 5e-13
gi|325675952|ref|ZP_08155635.1| TetR family transcriptional regu... 74.7 6e-12
>gi|15607831|ref|NP_215205.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15840095|ref|NP_335132.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31791875|ref|NP_854368.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97]
70 more sequence titles
Length=198
Score = 405 bits (1041), Expect = 2e-111, Method: Compositional matrix adjust.
Identities = 198/198 (100%), Positives = 198/198 (100%), Gaps = 0/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI
Sbjct 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL
Sbjct 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE
Sbjct 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALGAAFDVVGAGLDRLNQ
Sbjct 181 ALGAAFDVVGAGLDRLNQ 198
>gi|289756779|ref|ZP_06516157.1| transcriptional regulatory protein [Mycobacterium tuberculosis
T85]
gi|294996185|ref|ZP_06801876.1| transcriptional regulator [Mycobacterium tuberculosis 210]
gi|289712343|gb|EFD76355.1| transcriptional regulatory protein [Mycobacterium tuberculosis
T85]
gi|326905087|gb|EGE52020.1| transcriptional regulator [Mycobacterium tuberculosis W-148]
Length=198
Score = 404 bits (1038), Expect = 4e-111, Method: Compositional matrix adjust.
Identities = 197/198 (99%), Positives = 197/198 (99%), Gaps = 0/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI
Sbjct 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL
Sbjct 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIAKFV RRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE
Sbjct 121 QAYSMTMYAGWREVIAKFVTRRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALGAAFDVVGAGLDRLNQ
Sbjct 181 ALGAAFDVVGAGLDRLNQ 198
>gi|339293721|gb|AEJ45832.1| transcriptional regulator [Mycobacterium tuberculosis CCDC5079]
gi|339297360|gb|AEJ49470.1| transcriptional regulator [Mycobacterium tuberculosis CCDC5180]
Length=199
Score = 404 bits (1037), Expect = 5e-111, Method: Compositional matrix adjust.
Identities = 197/198 (99%), Positives = 197/198 (99%), Gaps = 0/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI
Sbjct 2 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 61
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL
Sbjct 62 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 121
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIAKFV RRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE
Sbjct 122 QAYSMTMYAGWREVIAKFVTRRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 181
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALGAAFDVVGAGLDRLNQ
Sbjct 182 ALGAAFDVVGAGLDRLNQ 199
>gi|297633189|ref|ZP_06950969.1| transcriptional regulator [Mycobacterium tuberculosis KZN 4207]
gi|328457414|gb|AEB02837.1| transcriptional regulator [Mycobacterium tuberculosis KZN 4207]
Length=198
Score = 402 bits (1034), Expect = 1e-110, Method: Compositional matrix adjust.
Identities = 197/198 (99%), Positives = 197/198 (99%), Gaps = 0/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI
Sbjct 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
WGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL
Sbjct 61 SWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE
Sbjct 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALGAAFDVVGAGLDRLNQ
Sbjct 181 ALGAAFDVVGAGLDRLNQ 198
>gi|340625710|ref|YP_004744162.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
gi|340003900|emb|CCC43032.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
Length=198
Score = 400 bits (1028), Expect = 5e-110, Method: Compositional matrix adjust.
Identities = 196/198 (99%), Positives = 196/198 (99%), Gaps = 0/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI
Sbjct 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDFSTHLAQLQ LLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL
Sbjct 61 PWGDFSTHLAQLQDLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIAKFVA RSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE
Sbjct 121 QAYSMTMYAGWREVIAKFVAHRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALGAAFDVVGAGLDRLNQ
Sbjct 181 ALGAAFDVVGAGLDRLNQ 198
>gi|240167692|ref|ZP_04746351.1| transcriptional regulator [Mycobacterium kansasii ATCC 12478]
Length=197
Score = 327 bits (838), Expect = 5e-88, Method: Compositional matrix adjust.
Identities = 158/197 (81%), Positives = 177/197 (90%), Gaps = 0/197 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
M HESRVGRRRSTT HHI+DVA++LF A GF +VSVDD+ARAAGIARR+LFRYYASKNAI
Sbjct 1 MLHESRVGRRRSTTKHHITDVAMDLFTARGFAEVSVDDVARAAGIARRSLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF HLA+LQ LLDNI+ +++L ALRAALLAFNTFDESET+RHR+RMR+IL+T EL
Sbjct 61 PWGDFDAHLAELQHLLDNIEPQVRLGTALRAALLAFNTFDESETVRHRQRMRIILETAEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWR VIA FVARR GG++TD +PQT+AWTMLGVALSAYEHWL DESVSL E
Sbjct 121 QAYSMTMYAGWRAVIAGFVARRLGGESTDLVPQTIAWTMLGVALSAYEHWLGDESVSLPE 180
Query 181 ALGAAFDVVGAGLDRLN 197
ALG AFDVVGAGLDRL
Sbjct 181 ALGDAFDVVGAGLDRLG 197
>gi|254822797|ref|ZP_05227798.1| hypothetical protein MintA_22899 [Mycobacterium intracellulare
ATCC 13950]
Length=197
Score = 322 bits (824), Expect = 3e-86, Method: Compositional matrix adjust.
Identities = 159/197 (81%), Positives = 172/197 (88%), Gaps = 1/197 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTP HI+DVAI+LF A GF DVSVDD+A AAGI+RRTLFRYYASKNAI
Sbjct 1 MP-QPRVGRRRSTTPAHITDVAIDLFTARGFADVSVDDVAHAAGISRRTLFRYYASKNAI 59
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLA L+ LLDN+DSR++L DALRAALLAFNTFDESET RHR+RMRVILQT EL
Sbjct 60 PWGDFDTHLAHLRDLLDNVDSRVRLGDALRAALLAFNTFDESETARHRQRMRVILQTAEL 119
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR KTTD +PQT AWTMLGVALSAYEHWL DESV L
Sbjct 120 QAYSMTMYAGWREVIAGFVARRCDCKTTDLLPQTAAWTMLGVALSAYEHWLSDESVPLPV 179
Query 181 ALGAAFDVVGAGLDRLN 197
ALG AFDVVGAGL+ L+
Sbjct 180 ALGNAFDVVGAGLNELD 196
>gi|41410249|ref|NP_963085.1| hypothetical protein MAP4151c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41399083|gb|AAS06701.1| hypothetical protein MAP_4151c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=210
Score = 317 bits (813), Expect = 5e-85, Method: Compositional matrix adjust.
Identities = 157/198 (80%), Positives = 172/198 (87%), Gaps = 1/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTPHHI+DVAI+LF A GF +VSVDD+A AAGI+RRTLFRYYASKNAI
Sbjct 14 MPQQ-RVGRRRSTTPHHITDVAIDLFTARGFAEVSVDDVAAAAGISRRTLFRYYASKNAI 72
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLA+L+ LLDN++SR+ L DALR ALLAFNTFDESET RHR+RMRVILQT EL
Sbjct 73 PWGDFDTHLARLRELLDNVESRVPLGDALRTALLAFNTFDESETARHRQRMRVILQTAEL 132
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR KTTD PQTVAW MLGVALSAYEHWL DESV L
Sbjct 133 QAYSMTMYAGWREVIAGFVARRCECKTTDLAPQTVAWMMLGVALSAYEHWLGDESVPLPV 192
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALG AFDVVGAGL+ L++
Sbjct 193 ALGNAFDVVGAGLNGLDR 210
>gi|118463601|ref|YP_883616.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|254776917|ref|ZP_05218433.1| hypothetical protein MaviaA2_19931 [Mycobacterium avium subsp.
avium ATCC 25291]
gi|118164888|gb|ABK65785.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=197
Score = 317 bits (811), Expect = 8e-85, Method: Compositional matrix adjust.
Identities = 157/198 (80%), Positives = 172/198 (87%), Gaps = 1/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTPHHI+DVAI+LF A GF +VSVDD+A AAGI+RRTLFRYYASKNAI
Sbjct 1 MPQQ-RVGRRRSTTPHHITDVAIDLFTARGFAEVSVDDVAAAAGISRRTLFRYYASKNAI 59
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLA+L+ LLDN++SR+ L DALR ALLAFNTFDESET RHR+RMRVILQT EL
Sbjct 60 PWGDFDTHLARLRELLDNVESRVPLGDALRTALLAFNTFDESETARHRQRMRVILQTAEL 119
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR KTTD PQTVAW MLGVALSAYEHWL DESV L
Sbjct 120 QAYSMTMYAGWREVIAGFVARRCECKTTDLAPQTVAWMMLGVALSAYEHWLGDESVPLPV 179
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALG AFDVVGAGL+ L++
Sbjct 180 ALGNAFDVVGAGLNGLDR 197
>gi|336460678|gb|EGO39569.1| mycofactocin system transcriptional regulator [Mycobacterium
avium subsp. paratuberculosis S397]
Length=204
Score = 317 bits (811), Expect = 8e-85, Method: Compositional matrix adjust.
Identities = 157/198 (80%), Positives = 172/198 (87%), Gaps = 1/198 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTPHHI+DVAI+LF A GF +VSVDD+A AAGI+RRTLFRYYASKNAI
Sbjct 8 MPQQ-RVGRRRSTTPHHITDVAIDLFTARGFAEVSVDDVAAAAGISRRTLFRYYASKNAI 66
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLA+L+ LLDN++SR+ L DALR ALLAFNTFDESET RHR+RMRVILQT EL
Sbjct 67 PWGDFDTHLARLRELLDNVESRVPLGDALRTALLAFNTFDESETARHRQRMRVILQTAEL 126
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR KTTD PQTVAW MLGVALSAYEHWL DESV L
Sbjct 127 QAYSMTMYAGWREVIAGFVARRCECKTTDLAPQTVAWMMLGVALSAYEHWLGDESVPLPV 186
Query 181 ALGAAFDVVGAGLDRLNQ 198
ALG AFDVVGAGL+ L++
Sbjct 187 ALGNAFDVVGAGLNGLDR 204
>gi|118616555|ref|YP_904887.1| transcriptional regulator [Mycobacterium ulcerans Agy99]
gi|183981040|ref|YP_001849331.1| transcriptional regulator [Mycobacterium marinum M]
gi|118568665|gb|ABL03416.1| transcriptional regulator [Mycobacterium ulcerans Agy99]
gi|183174366|gb|ACC39476.1| transcriptional regulator [Mycobacterium marinum M]
Length=197
Score = 314 bits (804), Expect = 5e-84, Method: Compositional matrix adjust.
Identities = 155/197 (79%), Positives = 170/197 (87%), Gaps = 0/197 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
M HESR GRR STT HI+DVAI+LFAA F +VSVDD+A+AAGIARRTLFRYYASKNAI
Sbjct 1 MAHESRAGRRPSTTKRHIADVAIDLFAARTFAEVSVDDVAQAAGIARRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLAQLQ LL+ ID ++L ALR ALLAFNT+DESETIRHR+RMR+ILQT EL
Sbjct 61 PWGDFDTHLAQLQDLLERIDGHVRLGKALREALLAFNTYDESETIRHRQRMRIILQTAEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWR VIA FVARR K TD +PQTVAWTMLGVALSAYEHWL DESVSL E
Sbjct 121 QAYSMTMYAGWRAVIAGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLSDESVSLPE 180
Query 181 ALGAAFDVVGAGLDRLN 197
ALG AFDVVGAGL++L+
Sbjct 181 ALGNAFDVVGAGLEKLD 197
>gi|342861780|ref|ZP_08718425.1| hypothetical protein MCOL_22940 [Mycobacterium colombiense CECT
3035]
gi|342130597|gb|EGT83901.1| hypothetical protein MCOL_22940 [Mycobacterium colombiense CECT
3035]
Length=198
Score = 313 bits (803), Expect = 6e-84, Method: Compositional matrix adjust.
Identities = 156/197 (80%), Positives = 169/197 (86%), Gaps = 1/197 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTPHHI+DVAI++F A GF DVSVDD+A+AAGI+RRTLFRYYASKNAI
Sbjct 2 MP-QPRVGRRRSTTPHHITDVAIDMFTARGFADVSVDDVAQAAGISRRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF HLA L+ LLDN+D+ + L DALRAALLAFNTFDESET RHR+RMRVILQT EL
Sbjct 61 PWGDFDNHLAHLRDLLDNVDADVGLGDALRAALLAFNTFDESETARHRQRMRVILQTAEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR KT D +PQTVAWTMLGVALSAYEHWL DESV L
Sbjct 121 QAYSMTMYAGWREVIAGFVARRMDCKTADLLPQTVAWTMLGVALSAYEHWLGDESVPLPV 180
Query 181 ALGAAFDVVGAGLDRLN 197
ALG AFDVVGAGL L
Sbjct 181 ALGNAFDVVGAGLHGLG 197
>gi|296168545|ref|ZP_06850349.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896608|gb|EFG76247.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=198
Score = 310 bits (793), Expect = 9e-83, Method: Compositional matrix adjust.
Identities = 155/196 (80%), Positives = 166/196 (85%), Gaps = 1/196 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
MP + RVGRRRSTTPHHI+DVAIELF A GF DVSVDD+A+AAGI+RRTLFRYYASKNAI
Sbjct 2 MP-QPRVGRRRSTTPHHITDVAIELFGARGFADVSVDDVAQAAGISRRTLFRYYASKNAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF THLA L+ LLD++D R+ L ALR ALLAFNTF ESET RHR+RMRVILQT EL
Sbjct 61 PWGDFDTHLAHLRDLLDDVDPRVPLGQALRDALLAFNTFGESETARHRQRMRVILQTAEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWREVIA FVARR K TD +PQT AWTMLGVALSAYEHWL DESV L
Sbjct 121 QAYSMTMYAGWREVIAGFVARRLDCKPTDLVPQTAAWTMLGVALSAYEHWLSDESVPLPT 180
Query 181 ALGAAFDVVGAGLDRL 196
ALG AFDVV GLDRL
Sbjct 181 ALGNAFDVVRTGLDRL 196
>gi|333991991|ref|YP_004524605.1| transcriptional regulator [Mycobacterium sp. JDM601]
gi|333487959|gb|AEF37351.1| transcriptional regulator [Mycobacterium sp. JDM601]
Length=199
Score = 285 bits (730), Expect = 2e-75, Method: Compositional matrix adjust.
Identities = 141/191 (74%), Positives = 158/191 (83%), Gaps = 0/191 (0%)
Query 4 ESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWG 63
++RVGRRRSTT HI+ VAI+LFA GF++VSVDD+A+AAGIARRTLFRYY SKNAIPWG
Sbjct 9 QARVGRRRSTTREHITHVAIDLFATRGFSEVSVDDVAQAAGIARRTLFRYYPSKNAIPWG 68
Query 64 DFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAY 123
DF HL QL+ LLD I+ L DALRAALLAFNTFDE ET RHR+RMRVILQT ELQAY
Sbjct 69 DFDAHLHQLRELLDGIEPDAPLGDALRAALLAFNTFDEGETARHRRRMRVILQTDELQAY 128
Query 124 SMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALG 183
SMTMYAGWR VIA+FVARR+G D PQTVAWTMLGVALSAYEHWL DE ++L +ALG
Sbjct 129 SMTMYAGWRSVIAEFVARRAGVAPADLRPQTVAWTMLGVALSAYEHWLGDEQLALPQALG 188
Query 184 AAFDVVGAGLD 194
AFD + GLD
Sbjct 189 EAFDTIRGGLD 199
>gi|108797971|ref|YP_638168.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119867068|ref|YP_937020.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|126433634|ref|YP_001069325.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|108768390|gb|ABG07112.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119693157|gb|ABL90230.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
gi|126233434|gb|ABN96834.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=199
Score = 270 bits (690), Expect = 9e-71, Method: Compositional matrix adjust.
Identities = 134/192 (70%), Positives = 156/192 (82%), Gaps = 0/192 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
RVGRRRSTT HI+DVA+++FAA GF +VSVDD+A AAGIARRTLFRYY+SK+AIPWGDF
Sbjct 8 RVGRRRSTTQDHITDVALDMFAARGFDEVSVDDVAAAAGIARRTLFRYYSSKSAIPWGDF 67
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
HL ++ L D++D + + +ALRAALLAFN FD +ET RHR+RMRVILQT LQAYSM
Sbjct 68 DAHLEHMRHLFDDLDPTVPVDEALRAALLAFNHFDAAETARHRQRMRVILQTDALQAYSM 127
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
TMYAGWR VIA+FVA R G K D +PQTVAWTMLGVALSAYE WL DE+VSL +ALG A
Sbjct 128 TMYAGWRAVIAQFVADRIGVKAHDLVPQTVAWTMLGVALSAYEQWLADEAVSLAQALGDA 187
Query 186 FDVVGAGLDRLN 197
FD V GL L+
Sbjct 188 FDTVRDGLRALH 199
>gi|118472856|ref|YP_885803.1| transcriptional regulatory protein [Mycobacterium smegmatis str.
MC2 155]
gi|118174143|gb|ABK75039.1| probable transcriptional regulatory protein [Mycobacterium smegmatis
str. MC2 155]
Length=200
Score = 267 bits (683), Expect = 6e-70, Method: Compositional matrix adjust.
Identities = 135/197 (69%), Positives = 152/197 (78%), Gaps = 0/197 (0%)
Query 1 MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAI 60
M SR GRRRSTT HI+ VAI+LFAA GF VSVDD+A AAGI+RRTLFRYYASK+AI
Sbjct 1 MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDDVAAAAGISRRTLFRYYASKSAI 60
Query 61 PWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
PWGDF +HL LQ LL + S + L DALR ALL FNT+ + E HR+RMRVIL+T EL
Sbjct 61 PWGDFDSHLQHLQNLLRTLSSEVSLGDALREALLTFNTYADHEMAEHRQRMRVILETEEL 120
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTE 180
QAYSMTMYAGWR VIA++VA R G TTD MPQTVAW MLGVALSAYE+WL DESVSL
Sbjct 121 QAYSMTMYAGWRTVIAEYVADRLGMSTTDLMPQTVAWLMLGVALSAYENWLADESVSLRG 180
Query 181 ALGAAFDVVGAGLDRLN 197
A+ AAF+V GLD L
Sbjct 181 AIAAAFEVARPGLDALQ 197
>gi|120402305|ref|YP_952134.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119955123|gb|ABM12128.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=204
Score = 259 bits (663), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 127/190 (67%), Positives = 153/190 (81%), Gaps = 2/190 (1%)
Query 4 ESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWG 63
++RVGRRRST+ H+SDVAI+LF A GF DVSVDD+A AAGIARRTLFRYY SK+A+PWG
Sbjct 5 KARVGRRRSTSWEHLSDVAIDLFMARGFDDVSVDDVAAAAGIARRTLFRYYPSKSALPWG 64
Query 64 DFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAY 123
DF HL ++ LLD +D + +RDALR ALLAFN FD+++ RHR+RMR+IL+T LQAY
Sbjct 65 DFDAHLEHMRELLDELDPSVPIRDALRTALLAFNDFDDAD--RHRQRMRLILETEALQAY 122
Query 124 SMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALG 183
SMTMYAGWR V+A FVA R G + MPQTVAWTML V+LSAYE+WL DESVSL ALG
Sbjct 123 SMTMYAGWRAVVAAFVAGRLGVDPAELMPQTVAWTMLAVSLSAYEYWLADESVSLAAALG 182
Query 184 AAFDVVGAGL 193
AFD++ +GL
Sbjct 183 DAFDMLASGL 192
>gi|145225638|ref|YP_001136316.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|315445991|ref|YP_004078870.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
gi|145218124|gb|ABP47528.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
gi|315264294|gb|ADU01036.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=208
Score = 253 bits (646), Expect = 1e-65, Method: Compositional matrix adjust.
Identities = 125/193 (65%), Positives = 148/193 (77%), Gaps = 2/193 (1%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
RVGRRRST+ HISDVAI+LF A GF DVSVDD+A AAGIARRTLFRYY SK+A+PWGDF
Sbjct 7 RVGRRRSTSWEHISDVAIDLFMARGFDDVSVDDVASAAGIARRTLFRYYPSKSALPWGDF 66
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
HL ++ LL ++D + +RDALR ALLAFN FD+ + RHR+RMR+IL+T LQAYSM
Sbjct 67 DAHLDHMRALLADLDPEVPIRDALRTALLAFNDFDDPD--RHRQRMRLILETEALQAYSM 124
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
TMYAGWR V+A FVA R G D PQTVAWTML V+LSAYEHWL DE+ L +LG A
Sbjct 125 TMYAGWRAVVAAFVADRLGVGGDDLRPQTVAWTMLAVSLSAYEHWLADETACLQSSLGEA 184
Query 186 FDVVGAGLDRLNQ 198
FD++ +GL L
Sbjct 185 FDLLASGLSGLES 197
>gi|111023033|ref|YP_706005.1| AcrR family transcriptional regulator [Rhodococcus jostii RHA1]
gi|110822563|gb|ABG97847.1| transcriptional regulator, AcrR family protein [Rhodococcus jostii
RHA1]
Length=207
Score = 214 bits (546), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 107/194 (56%), Positives = 131/194 (68%), Gaps = 0/194 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
SR+GRR STT IS V IELF GF SVD++A A+GIARRTLFRY+ SKNAIPWGD
Sbjct 9 SRIGRRPSTTQDRISTVGIELFTEQGFDATSVDEVAEASGIARRTLFRYFPSKNAIPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HLA+++ L I + D L AALL FN F SE I HRKRM +IL+ P LQAYS
Sbjct 69 FDAHLAEMRAQLAAQPDDIPIVDGLTAALLQFNAFPASEEINHRKRMGLILRVPALQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR VIA++VA R G TD +P+TV + +LGVA+SAYE WL D+S+ L E L +
Sbjct 129 VVMYEGWRNVIAEYVASRLGTSPTDHVPRTVGYLLLGVAMSAYEQWLDDDSLELNELLAS 188
Query 185 AFDVVGAGLDRLNQ 198
+ GL L +
Sbjct 189 GMQSLYDGLSSLGE 202
>gi|158430737|pdb|2RAE|A Chain A, Crystal Structure Of A TetrACRR FAMILY TRANSCRIPTIONAL
Regulator From Rhodococcus Sp. Rha1
Length=207
Score = 214 bits (545), Expect = 5e-54, Method: Compositional matrix adjust.
Identities = 107/194 (56%), Positives = 131/194 (68%), Gaps = 0/194 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
SR+GRR STT IS V IELF GF SVD++A A+GIARRTLFRY+ SKNAIPWGD
Sbjct 9 SRIGRRPSTTQDRISTVGIELFTEQGFDATSVDEVAEASGIARRTLFRYFPSKNAIPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HLA+++ L I + D L AALL FN F SE I HRKRM +IL+ P LQAYS
Sbjct 69 FDAHLAEMRAQLAAQPDDIPIVDGLTAALLQFNAFPASEEINHRKRMGLILRVPALQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR VIA++VA R G TD +P+TV + +LGVA+SAYE WL D+S+ L E L +
Sbjct 129 VVMYEGWRNVIAEYVASRLGTSPTDHVPRTVGYLLLGVAMSAYEQWLDDDSLELNELLAS 188
Query 185 AFDVVGAGLDRLNQ 198
+ GL L +
Sbjct 189 GMQSLYDGLSSLGE 202
>gi|226365537|ref|YP_002783320.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
gi|226244027|dbj|BAH54375.1| putative TetR family transcriptional regulator [Rhodococcus opacus
B4]
Length=205
Score = 214 bits (544), Expect = 7e-54, Method: Compositional matrix adjust.
Identities = 107/194 (56%), Positives = 131/194 (68%), Gaps = 0/194 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
SR+GRR STT IS V IELF GF SVD++A A+GIARRTLFRY+ SKNAIPWGD
Sbjct 9 SRIGRRPSTTQDRISTVGIELFTEQGFDATSVDEVAEASGIARRTLFRYFPSKNAIPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HLA+++ L I + D L AALL FN F ESE HRKRM +IL+ P LQAYS
Sbjct 69 FDAHLAEMRAQLAAQPGDIPIVDGLTAALLQFNAFPESEEANHRKRMGLILRVPALQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR VIA++VA R G TD +P+TV + +LGVA+SAYE WL D+S+ L E L +
Sbjct 129 VVMYEGWRNVIAEYVAGRLGVSPTDHVPRTVGYLLLGVAMSAYEQWLDDDSLELNELLAS 188
Query 185 AFDVVGAGLDRLNQ 198
+ GL L +
Sbjct 189 GMQSLYDGLSSLGE 202
>gi|226305285|ref|YP_002765243.1| TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
gi|226184400|dbj|BAH32504.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
Length=199
Score = 213 bits (543), Expect = 9e-54, Method: Compositional matrix adjust.
Identities = 104/189 (56%), Positives = 133/189 (71%), Gaps = 0/189 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
+R+GRR STT IS + IELF+ GF +VSVD IA AAGIARRT FRY+ SKNA+PWGD
Sbjct 9 ARIGRRPSTTREGISTIGIELFSTVGFNEVSVDQIADAAGIARRTFFRYFPSKNAVPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HL +++ LD++ + I L DAL +ALL FNTF ET HRKRM +IL+ P LQAYS
Sbjct 69 FDGHLDEMREHLDSLPADIPLVDALESALLTFNTFPPEETAVHRKRMELILEVPTLQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR+V+A +VARR + TD P+TV + +LGVA+SAYE WL D+S+ L E L
Sbjct 129 VVMYEGWRQVVADYVARRMNLEPTDHGPRTVGYLLLGVAMSAYEQWLTDDSLELPELLKT 188
Query 185 AFDVVGAGL 193
+ G+
Sbjct 189 GTQSLRTGI 197
>gi|229490652|ref|ZP_04384490.1| transcriptional regulator, AcrR family [Rhodococcus erythropolis
SK121]
gi|229322472|gb|EEN88255.1| transcriptional regulator, AcrR family [Rhodococcus erythropolis
SK121]
Length=199
Score = 213 bits (542), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 103/189 (55%), Positives = 133/189 (71%), Gaps = 0/189 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
+R+GRR STT IS + IELF+ GF +VSVD IA AAGIARRT FRY+ SKNA+PWGD
Sbjct 9 ARIGRRPSTTKEGISTIGIELFSTVGFNEVSVDQIADAAGIARRTFFRYFPSKNAVPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HL +++ LD++ + I L DAL +ALL FNTF ET HRKRM +IL+ P LQAYS
Sbjct 69 FDGHLDEMREHLDSLPADIPLVDALESALLTFNTFPPEETAVHRKRMELILEVPTLQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR+V+A +VARR + +D P+TV + +LGVA+SAYE WL D+S+ L E L
Sbjct 129 VVMYEGWRQVVADYVARRMNLEPSDHGPRTVGYLLLGVAMSAYEQWLTDDSLELPELLKT 188
Query 185 AFDVVGAGL 193
+ G+
Sbjct 189 GTQSLRTGI 197
>gi|169630916|ref|YP_001704565.1| transcriptional regulatory protein TetR [Mycobacterium abscessus
ATCC 19977]
gi|169242883|emb|CAM63911.1| Probable transcriptional regulatory protein TetR [Mycobacterium
abscessus]
Length=198
Score = 212 bits (540), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 118/191 (62%), Positives = 136/191 (72%), Gaps = 0/191 (0%)
Query 3 HESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPW 62
+RVGRR STT I+ VA+ LFA HGF +VSVDDIA AAGIARRT+FRYY+SKNAI W
Sbjct 4 QPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRTVFRYYSSKNAIVW 63
Query 63 GDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQA 122
GDF +HL ++ LLD + ALR A+L FN F ET RHR RMR+IL+ P LQA
Sbjct 64 GDFDSHLGVMRALLDETADTVDTSTALRQAVLTFNDFPVDETPRHRMRMRMILEVPALQA 123
Query 123 YSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEAL 182
YSM MY GWR+VIA+FVARRSG +PQTVAWT+LGVAL+AYE WL DES LT L
Sbjct 124 YSMLMYTGWRDVIAQFVARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLADESSKLTTLL 183
Query 183 GAAFDVVGAGL 193
G FD GL
Sbjct 184 GKGFDAAEVGL 194
>gi|3873400|gb|AAC77476.1| unknown [Rhodococcus erythropolis]
Length=185
Score = 211 bits (536), Expect = 5e-53, Method: Compositional matrix adjust.
Identities = 101/177 (58%), Positives = 130/177 (74%), Gaps = 0/177 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
+R+GRR STT IS + IELF+ GF +VSVD IA AAGIARRT FRY+ SKNA+PWGD
Sbjct 9 ARIGRRPSTTREGISTIGIELFSTVGFNEVSVDQIADAAGIARRTFFRYFPSKNAVPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HL +++ LD++ + I L DAL +ALL FNTF ET HRKRM +IL+ P LQAYS
Sbjct 69 FDGHLDEMREHLDSLPADIPLVDALESALLTFNTFPPEETAVHRKRMELILEVPTLQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA 181
+ MY GWR+V+A +VARR + TD P+TV + +LGVA+SAYE WL D+S+ L ++
Sbjct 129 VVMYEGWRQVVADYVARRMNLEPTDHGPRTVGYLLLGVAMSAYEQWLTDDSLELPDS 185
>gi|312140962|ref|YP_004008298.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
gi|325675402|ref|ZP_08155086.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
gi|311890301|emb|CBH49619.1| putative TetR family transcriptional regulator [Rhodococcus equi
103S]
gi|325553373|gb|EGD23051.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
Length=210
Score = 199 bits (505), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 101/194 (53%), Positives = 130/194 (68%), Gaps = 0/194 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
SR+GRR +TT I+ V I+LFA GF D SVDDIA AAGIARRT FRY+ SKNA+PWGD
Sbjct 9 SRIGRRPTTTRDRIAAVGIDLFATRGFDDTSVDDIAEAAGIARRTFFRYFPSKNAVPWGD 68
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HLA+++ LL + + D L AA+L FNTF T HR+RM +I P LQAYS
Sbjct 69 FDAHLAEMRTLLAEMPDDEPILDNLVAAVLEFNTFPPEVTDGHRRRMELIFVVPALQAYS 128
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
+ MY GWR+VIA++VA R + TD +P+TV + MLGVA+ AYE WL D+S L + L
Sbjct 129 VVMYEGWRKVIAEYVAGRLHLQATDQLPRTVGYLMLGVAMGAYETWLADDSADLIDLLTK 188
Query 185 AFDVVGAGLDRLNQ 198
++ GL L++
Sbjct 189 GSRMLYTGLSELHE 202
>gi|262203645|ref|YP_003274853.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262086992|gb|ACY22960.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=209
Score = 190 bits (483), Expect = 9e-47, Method: Compositional matrix adjust.
Identities = 96/175 (55%), Positives = 117/175 (67%), Gaps = 0/175 (0%)
Query 4 ESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWG 63
+S GRR T+ IS +AI+LF GF + SVDDIA AAGIARRTLFRYY SKNA+PWG
Sbjct 16 KSAAGRRPLTSRAQISTIAIDLFTERGFDETSVDDIAEAAGIARRTLFRYYPSKNAVPWG 75
Query 64 DFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAY 123
DF HLAQ++ LL I S + + DAL+ AL++FN +E HR+RM ++L P LQA+
Sbjct 76 DFDGHLAQMRELLARIPSDLSIADALQMALVSFNRVPPTERDSHRRRMALLLGVPALQAH 135
Query 124 SMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSL 178
SM MYA WR VIA F A R G D +PQT+ W LG AL+AYE WL D L
Sbjct 136 SMLMYAEWRHVIADFCAARLGLDEHDHLPQTIGWLCLGTALAAYEAWLADPGSDL 190
>gi|343927804|ref|ZP_08767272.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
gi|343762445|dbj|GAA14198.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
Length=209
Score = 187 bits (475), Expect = 7e-46, Method: Compositional matrix adjust.
Identities = 96/197 (49%), Positives = 120/197 (61%), Gaps = 0/197 (0%)
Query 2 PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIP 61
P + GRR ++ IS +AI LF GF + SVDDIA AAGIARRTLFRYY+SKN IP
Sbjct 11 PGRAAPGRRPISSRARISALAIGLFTTRGFEETSVDDIAEAAGIARRTLFRYYSSKNEIP 70
Query 62 WGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQ 121
WG+F HL +L+GLL I + I + DAL AL+ FN E HR+RM ++L P LQ
Sbjct 71 WGEFDDHLGELRGLLAQIPTDIPMADALVDALVVFNRVPPEELENHRRRMSLLLGVPALQ 130
Query 122 AYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA 181
A+SM MYA WR VIA+F A R G D +PQT+ W LG AL+AYE WL + L
Sbjct 131 AHSMIMYADWRHVIAEFCAARLGLDENDHLPQTIGWLCLGAALAAYEQWLANPDADLERL 190
Query 182 LGAAFDVVGAGLDRLNQ 198
+ V G+ L +
Sbjct 191 ISDGARTVATGVASLTR 207
>gi|326384863|ref|ZP_08206538.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395]
gi|326196382|gb|EGD53581.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395]
Length=211
Score = 182 bits (462), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 96/189 (51%), Positives = 122/189 (65%), Gaps = 0/189 (0%)
Query 8 GRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFST 67
GR +TT +S +AI+LF +GF + SVDDIA AAGIARRTLFRYY SKN++ WG+F+
Sbjct 12 GRPAATTRGRLSSLAIDLFTENGFDETSVDDIANAAGIARRTLFRYYPSKNSLAWGEFTE 71
Query 68 HLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTM 127
HL L+ LL + + + L ALR AL+AFNT E E HR+RM ++L P LQA+SM M
Sbjct 72 HLDGLRDLLRSSPADVPLGVALRDALIAFNTVPEPELDEHRRRMALLLGVPALQAHSMLM 131
Query 128 YAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFD 187
YA WR+VIA A R G +PQT+AW LG AL+AY+ WL D LTE L
Sbjct 132 YADWRQVIADHCAERLGLDPASHIPQTIAWQTLGTALAAYDQWLLDPDSDLTELLEIGSR 191
Query 188 VVGAGLDRL 196
V+ G+ L
Sbjct 192 VLIGGVASL 200
>gi|336178663|ref|YP_004584038.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
gi|334859643|gb|AEH10117.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
Length=224
Score = 171 bits (433), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 88/181 (49%), Positives = 113/181 (63%), Gaps = 0/181 (0%)
Query 13 TTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQL 72
T+ + +A ELFA GF +VDDIARAAGI RRT FRY+ SKN + WG F LA+L
Sbjct 26 TSRAELEHLAFELFAERGFERTTVDDIARAAGIGRRTFFRYFPSKNDVVWGAFDEELARL 85
Query 73 QGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWR 132
+ L + L DA+R AL+ FN +ET HR+RMR+IL TP LQA+S Y WR
Sbjct 86 RADLRTYPPDVPLMDAVRQALIEFNRVGPAETPWHRRRMRLILGTPALQAHSTLRYVAWR 145
Query 133 EVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAG 192
+VIA+F+ R G PQ +A+ LGVA++AYE WLR E++ LTE L AA + AG
Sbjct 146 QVIAEFIGNRIGQDEHALAPQAIAYATLGVAIAAYEQWLRHENLELTELLDAAMRKLAAG 205
Query 193 L 193
Sbjct 206 F 206
>gi|324999705|ref|ZP_08120817.1| TetR family transcriptional regulator [Pseudonocardia sp. P1]
Length=212
Score = 167 bits (423), Expect = 8e-40, Method: Compositional matrix adjust.
Identities = 81/187 (44%), Positives = 115/187 (62%), Gaps = 0/187 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
R GRR T+ + I +A+E+F+ GF +VDD+A AAGI RRT FRYYASKN + WG F
Sbjct 20 RAGRRPVTSRYEIEHIALEMFSEQGFDHTTVDDVAHAAGIGRRTFFRYYASKNDVAWGAF 79
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
L +++ +L + + + +R A+L FN D E HR+R+R+IL+TP LQA+S
Sbjct 80 DEQLVRMRAVLAAQSPDLPVLEGIRRAVLEFNHVDPDEQPWHRRRLRLILETPALQAHST 139
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
YA WR+V+A VA R G ++ +PQ++ LGV L+AYEHWL D+ L + L
Sbjct 140 LRYAAWRQVVADHVAERRGEPSSGLVPQSLGHACLGVCLAAYEHWLADDGAELADLLDDV 199
Query 186 FDVVGAG 192
F + G
Sbjct 200 FGSLTQG 206
>gi|111223716|ref|YP_714510.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111151248|emb|CAJ62960.1| putative TetR family transcriptional regulator [Frankia alni
ACN14a]
Length=197
Score = 166 bits (420), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 86/188 (46%), Positives = 115/188 (62%), Gaps = 0/188 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
R GRR +T+ + +A+++F GF + +VDDIARAAGI RRT FRY+ASKN +PWGDF
Sbjct 7 RTGRRPATSAAELEHLALQIFTERGFEETTVDDIARAAGIGRRTFFRYFASKNDVPWGDF 66
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
L ++ L + + LR A+L FNT+ +E R+RM +IL+TP LQA+S
Sbjct 67 DGQLEVMRASLASAAAGEPTVAVLRRAILDFNTYPPAEGAWLRRRMTLILRTPALQAHST 126
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
YA WR V+A+FVARR G PQ VA LGVA++AYE WLR+E L L A
Sbjct 127 LRYASWRGVLAEFVARRVGQPADALTPQAVAAAHLGVAVTAYEQWLREEGTDLVAILDEA 186
Query 186 FDVVGAGL 193
++ G
Sbjct 187 LGLLATGF 194
>gi|312198474|ref|YP_004018535.1| TetR family transcriptional regulator [Frankia sp. EuI1c]
gi|311229810|gb|ADP82665.1| regulatory protein TetR [Frankia sp. EuI1c]
Length=208
Score = 162 bits (409), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 85/189 (45%), Positives = 112/189 (60%), Gaps = 0/189 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
R GRR TT + A+ +F GF +VDDIA AGI RRT FRYYASKN + WG+
Sbjct 16 GRAGRRPVTTAAELERHALLIFEERGFDATTVDDIAAVAGIGRRTFFRYYASKNDVAWGE 75
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F HL ++ L + + + ALR A+L FNT+ +E HR+RM +IL+TP LQA+S
Sbjct 76 FDAHLETMRAALAATPAEVPVLAALRRAILDFNTYPVAEADWHRRRMALILRTPALQAHS 135
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
YA WR V+A+FVA R+G +T P+ VAW LGVA++ YE WL L L
Sbjct 136 TLRYAAWRAVVAEFVAARTGRQTDALEPRAVAWAFLGVAVAGYEEWLARPGADLGPILDQ 195
Query 185 AFDVVGAGL 193
A ++ GL
Sbjct 196 ALRLLTEGL 204
>gi|333922025|ref|YP_004495606.1| TetR family transcriptional regulator [Amycolicicoccus subflavus
DQS3-9A1]
gi|333484246|gb|AEF42806.1| Transcriptional regulator, TetR family [Amycolicicoccus subflavus
DQS3-9A1]
Length=206
Score = 161 bits (408), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 83/184 (46%), Positives = 111/184 (61%), Gaps = 0/184 (0%)
Query 2 PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIP 61
P + R GR +T+ I VA +LF + GF +VDDIARAAGI RRT FRY+ SKN IP
Sbjct 4 PQQGRQGRPSATSHAWIERVAFDLFESKGFEATTVDDIARAAGIGRRTFFRYFDSKNDIP 63
Query 62 WGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQ 121
WG F L + L + S + + A+ +LAFNT+ +HR+RM +IL+TP LQ
Sbjct 64 WGQFDASLVSFRETLRTMPSTLPVHVAVHQGVLAFNTYPPEAVPQHRQRMALILKTPALQ 123
Query 122 AYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA 181
A+S+ YA WR VIA FVA R +D +P+T+ L +A++AYEHWL + S L
Sbjct 124 AHSVLRYAEWRAVIADFVAARMSLPASDLLPRTIGHVSLALAVTAYEHWLENPSEDLLVV 183
Query 182 LGAA 185
L A
Sbjct 184 LDNA 187
>gi|331694457|ref|YP_004330696.1| TetR family transcriptional regulator [Pseudonocardia dioxanivorans
CB1190]
gi|326949146|gb|AEA22843.1| transcriptional regulator, TetR family [Pseudonocardia dioxanivorans
CB1190]
Length=205
Score = 160 bits (404), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 87/188 (47%), Positives = 111/188 (60%), Gaps = 1/188 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
R GRR T+ I +A++LFA GF +VDDIA+AAGI RRT FRYYASKN +PWG F
Sbjct 11 RAGRRPVTSRFEIEHIALDLFAERGFDATTVDDIAQAAGIGRRTFFRYYASKNDVPWGAF 70
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
L +++ + + + A+R +L FN E HR+R+R+IL TP LQAYS
Sbjct 71 DEQLTRMRSTFAALPPDVPVMRAVREVVLDFNDVAPDEQPWHRQRLRLILGTPTLQAYST 130
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
YA WR+V+A FVA R G D +P TV LG AL+AYE WL + L L A
Sbjct 131 LRYAAWRQVVADFVAARLGTTPDDLVPLTVGHASLGAALAAYETWLTTDH-DLRSLLDEA 189
Query 186 FDVVGAGL 193
F + AGL
Sbjct 190 FRALEAGL 197
>gi|319950928|ref|ZP_08024804.1| regulatory protein TetR [Dietzia cinnamea P4]
gi|319435400|gb|EFV90644.1| regulatory protein TetR [Dietzia cinnamea P4]
Length=193
Score = 155 bits (393), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 83/164 (51%), Positives = 102/164 (63%), Gaps = 0/164 (0%)
Query 8 GRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFST 67
GRR STT I DVA++LFA G+ SVD IA AA I+RRTLFRY+ K AI WG+F
Sbjct 8 GRRPSTTRASIVDVALDLFARQGYEATSVDQIAEAAHISRRTLFRYFPGKAAIAWGEFDE 67
Query 68 HLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTM 127
+ + G L + LRDAL AL+AFNTF S+T HR RMR++L ELQA+S +
Sbjct 68 QIQLMLGYLAGVPEDTPLRDALADALIAFNTFPPSQTEVHRLRMRLLLGVDELQAHSTLV 127
Query 128 YAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWL 171
YA WR +A FVA R G D +P A LG+ALSAY W+
Sbjct 128 YADWRRAVAGFVADRRGETVDDLVPAATAHAALGIALSAYRLWV 171
>gi|258651019|ref|YP_003200175.1| TetR family transcriptional regulator [Nakamurella multipartita
DSM 44233]
gi|258554244|gb|ACV77186.1| transcriptional regulator, TetR family [Nakamurella multipartita
DSM 44233]
Length=212
Score = 151 bits (382), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 76/171 (45%), Positives = 104/171 (61%), Gaps = 0/171 (0%)
Query 21 VAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNID 80
+ +E+F+ GF SVD+IA AAGI RRT FRY+ SKN WG+F + LA +
Sbjct 35 ICLEIFSERGFEVTSVDEIAAAAGIGRRTFFRYFKSKNDAVWGEFDSQLAAFAHWFAHCP 94
Query 81 SRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVA 140
+ + A+RAA++ FN+FD T R RMR+IL +P LQAYS YA WR+V+A+F A
Sbjct 95 PELTVVQAIRAAVIDFNSFDRPATESLRTRMRLILSSPSLQAYSTLHYAAWRDVVARFAA 154
Query 141 RRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGA 191
R G D +P+T+ LG ALSAYE WL D+ L E L + ++G+
Sbjct 155 GRLGLDPDDLIPRTLGHLALGAALSAYEQWLADDGAELIELLHQSLALLGS 205
>gi|288919778|ref|ZP_06414103.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288348786|gb|EFC83038.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=220
Score = 149 bits (376), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 79/179 (45%), Positives = 102/179 (57%), Gaps = 0/179 (0%)
Query 8 GRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFST 67
GR T I A +F HGF ++D IA AAG+ RRTL RYY SKN IPWG F
Sbjct 34 GRPPVTDHASIERAAFAVFTEHGFDATTLDAIAAAAGVGRRTLLRYYPSKNDIPWGQFDE 93
Query 68 HLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTM 127
L LQ L + I + +A+ A+LAFN D + +HR+RM ++L+TP L A+S
Sbjct 94 SLVGLQKTLAAMPRDIPVHEAVHRAVLAFNHVDAAAVAQHRQRMTLLLRTPTLMAHSALK 153
Query 128 YAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAF 186
Y WR VIA +VA R G D +P+TV L +A+SAYE WL DE ++ E L A
Sbjct 154 YRQWRRVIASYVAERHGLTPEDLLPRTVGHVALAIAVSAYEQWLDDEQRTIEEILDEAL 212
>gi|258652559|ref|YP_003201715.1| TetR family transcriptional regulator [Nakamurella multipartita
DSM 44233]
gi|258555784|gb|ACV78726.1| transcriptional regulator, TetR family [Nakamurella multipartita
DSM 44233]
Length=230
Score = 143 bits (360), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 75/165 (46%), Positives = 102/165 (62%), Gaps = 0/165 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
R GR+ +++ I A LF GF +VDDIA AAGIARRT F Y+ASKN +PWG F
Sbjct 18 RPGRQPASSRTEIEHAAFRLFDERGFEQTTVDDIAGAAGIARRTFFSYFASKNDVPWGSF 77
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
L L+ +LD + + +A+R A+LAFNT D +E HRKR+ +IL TP LQA+S
Sbjct 78 DRELDYLRAVLDQTPDSVPVMEAIRRAVLAFNTVDPAEQPWHRKRLALILSTPALQAHST 137
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHW 170
YA WR+V+ +FVARR + QT+ + L A++AY+ W
Sbjct 138 LRYAQWRQVVCEFVARRLVAPVGSLLVQTIGYASLAAAIAAYDVW 182
>gi|158315008|ref|YP_001507516.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158110413|gb|ABW12610.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=209
Score = 142 bits (359), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 80/185 (44%), Positives = 101/185 (55%), Gaps = 0/185 (0%)
Query 2 PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIP 61
P + GR T I A +F GF ++D IA AAG+ RRTL RYY SKN IP
Sbjct 13 PSKRPKGRPPVTDHAAIERAAFVVFTERGFDATTLDAIAEAAGVGRRTLLRYYPSKNDIP 72
Query 62 WGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQ 121
WG F L LQ L + I + A+ A+LAFN +HR+RM ++L+TP LQ
Sbjct 73 WGQFDESLLDLQKSLAAMPRDIPVHVAVHRAVLAFNHVGPDAVAQHRQRMTLLLRTPTLQ 132
Query 122 AYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEA 181
A+S Y WREVIA +VA R G D +P+TV L +ALSAYE WL E ++ E
Sbjct 133 AHSALKYRRWREVIASYVAERHGLIADDLLPRTVGQVTLALALSAYEQWLEHEDRTIGEI 192
Query 182 LGAAF 186
L A
Sbjct 193 LDEAL 197
>gi|269126599|ref|YP_003299969.1| TetR family transcriptional regulator [Thermomonospora curvata
DSM 43183]
gi|268311557|gb|ACY97931.1| transcriptional regulator, TetR family [Thermomonospora curvata
DSM 43183]
Length=211
Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 87/191 (46%), Positives = 114/191 (60%), Gaps = 1/191 (0%)
Query 4 ESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWG 63
++ +GR R T+ + A ELFA GF + +VDDIA AAGI RRT FRY ASKN + WG
Sbjct 12 QTVMGRPRVTSRATLEARAFELFARKGFEETTVDDIAAAAGIGRRTFFRYCASKNDLVWG 71
Query 64 DFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAY 123
DF HL +L+ LL+ D + + LR A++ FN FD + HR+RM +IL+ P LQA
Sbjct 72 DFEGHLLKLRRLLEEADPTLPTMEVLRRAVVEFNRFDPRDVPWHRQRMELILKVPTLQAD 131
Query 124 SMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLR-DESVSLTEAL 182
+ YA WR VIA+FVA R+G + P+ +L A++AYEHWL D L E L
Sbjct 132 ATLRYASWRAVIAEFVASRTGLPPSAMTPRLAGHVLLAAAVAAYEHWLSGDGDAELAELL 191
Query 183 GAAFDVVGAGL 193
A V AGL
Sbjct 192 DKAIRRVSAGL 202
>gi|288918285|ref|ZP_06412639.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288350322|gb|EFC84545.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=209
Score = 128 bits (322), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 70/176 (40%), Positives = 101/176 (58%), Gaps = 0/176 (0%)
Query 11 RSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLA 70
+ T+ I A+E+ AA GF DV+V++IA AAG++RRT FRY+ASKN I +G+F+ L
Sbjct 6 QQTSVEAIEKAALEMIAARGFQDVTVEEIANAAGVSRRTFFRYFASKNDILFGNFAGLLK 65
Query 71 QLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAG 130
+L ++ + DA+ ++ FN + + HR+RM +IL TP L+A + A
Sbjct 66 ELDDWFASVPDDRPMFDAIAEGVMRFNRANTDGPVAHRQRMELILLTPALKANASLRNAE 125
Query 131 WREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAF 186
W VIA++ ARR PQ + LG A +AYE WLRD S L E + AF
Sbjct 126 WLAVIARYAARRLDEPEDALGPQLIGHVSLGAANAAYERWLRDASADLNELVRRAF 181
>gi|158315129|ref|YP_001507637.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158110534|gb|ABW12731.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=226
Score = 112 bits (280), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 62/181 (35%), Positives = 91/181 (51%), Gaps = 2/181 (1%)
Query 1 MPHES--RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKN 58
MP S R GR R T+ + +A+ LFA G+ + +VD IA AAG++RRT FRY+ +K+
Sbjct 1 MPQTSPDRRGRPRGTSARKLELIALRLFAEQGYHETTVDQIAAAAGVSRRTFFRYFDAKS 60
Query 59 AIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTP 118
+ W +F + ++ L + + DA+R A++A N + + R RM +I P
Sbjct 61 QVLWNEFDNEVTTIRANLQQTSGGLPVMDAVRHAVIAANYYRAEDVPELRMRMHLISTVP 120
Query 119 ELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSL 178
EL A + Y W I +FVARR+ P V L V +AYE W L
Sbjct 121 ELVASATVHYDAWERAITEFVARRTDQPADSLYPLAVGRATLAVCRAAYERWSTHADADL 180
Query 179 T 179
T
Sbjct 181 T 181
>gi|284993286|ref|YP_003411841.1| TetR family transcriptional regulator [Geodermatophilus obscurus
DSM 43160]
gi|284066532|gb|ADB77470.1| transcriptional regulator, TetR family [Geodermatophilus obscurus
DSM 43160]
Length=203
Score = 111 bits (278), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/186 (38%), Positives = 101/186 (55%), Gaps = 0/186 (0%)
Query 11 RSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLA 70
R+ T + A+ELF +GF V+ DDIA AAGI+RRT FR +A+K WG+F H+
Sbjct 4 RADTRARVQQAALELFTLNGFEQVTADDIAEAAGISRRTFFRCFATKADAVWGEFGAHVD 63
Query 71 QLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAG 130
+L+ LL + ++ A + N + + R+RM +IL P LQA+S YA
Sbjct 64 RLERLLAATRDDQPVLASICGAYVEVNDYAAEDLPILRQRMALILGEPALQAHSQVRYAD 123
Query 131 WREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVG 190
V+A+ VARR+G +P+ VA + A +A+E WL D + +L L AAFD +
Sbjct 124 VDRVVAEHVARRTGQSPAALLPRLVATSTRAAATTAFEVWLADGTTTLAADLHAAFDQLA 183
Query 191 AGLDRL 196
G L
Sbjct 184 LGFPGL 189
>gi|302529485|ref|ZP_07281827.1| transcriptional regulator [Streptomyces sp. AA4]
gi|302438380|gb|EFL10196.1| transcriptional regulator [Streptomyces sp. AA4]
Length=210
Score = 107 bits (267), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 58/181 (33%), Positives = 92/181 (51%), Gaps = 0/181 (0%)
Query 13 TTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQL 72
T+ + ++A+ LF GF + +VD IA AAG++RRT FRYY +K+ + W +F + + +
Sbjct 19 TSARQLEEIALRLFTEQGFHETTVDQIAAAAGVSRRTFFRYYDAKSDVLWNEFDSEVDTI 78
Query 73 QGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWR 132
+ LL + + + +A+R A+LA N + + R RM ++ EL A + Y W
Sbjct 79 RELLADSPEDVPVLEAVRRAVLAANHYRAEDVPELRMRMNLLSTVAELAASATRHYDAWE 138
Query 133 EVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAG 192
+ +FVARR+G P V +L +AYE W LT L A + AG
Sbjct 139 RAVIQFVARRTGQGEDSLYPLAVGRAVLATCRAAYERWSARADADLTLYLDAGLRALAAG 198
Query 193 L 193
Sbjct 199 F 199
>gi|54025179|ref|YP_119421.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
gi|54016687|dbj|BAD58057.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
Length=196
Score = 98.6 bits (244), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 59/189 (32%), Positives = 90/189 (48%), Gaps = 0/189 (0%)
Query 5 SRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGD 64
+R GR R TT + +A+ LF GF + +V+ IA AAGI+ RT FRY+ SK + W
Sbjct 4 TRAGRPRGTTKRDLELIAMRLFTEQGFDNTTVEHIAAAAGISGRTFFRYFPSKAEVLWHQ 63
Query 65 FSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYS 124
F + L+ + + + A+R ++ NT+ + R RM ++ P L A +
Sbjct 64 FDAEVDALRTAFATVPDELPMMTAVRRVVVNANTYRAEDVAELRTRMHLVATVPALAATA 123
Query 125 MTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGA 184
Y W ++ F ARR G +P V T L A +A++ WLR+ LT L
Sbjct 124 GPHYDAWERAVSAFAARRLGEPEDALVPLAVGRTTLAAARAAFDAWLRNADADLTVYLDQ 183
Query 185 AFDVVGAGL 193
A + G
Sbjct 184 ALSALERGF 192
>gi|50954607|ref|YP_061895.1| TetR family transcriptional regulator [Leifsonia xyli subsp.
xyli str. CTCB07]
gi|50951089|gb|AAT88790.1| transcriptional regulator, TetR family [Leifsonia xyli subsp.
xyli str. CTCB07]
Length=201
Score = 90.5 bits (223), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 57/189 (31%), Positives = 92/189 (49%), Gaps = 0/189 (0%)
Query 6 RVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDF 65
R GR P I+ +A+ FA HG+ ++DDIA AG+ RRTLFRY+ SK + WG
Sbjct 12 RRGRPYGVDPERIALLALHRFAVHGYDATTMDDIATLAGVGRRTLFRYFPSKPELVWGGL 71
Query 66 STHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSM 125
+ +++ +LD +RD L A F+ R R+R++ PEL A+ +
Sbjct 72 EPVVERMRAVLDAPPEGEPVRDTLARAFAHSLDFEPGAREAARLRLRLMASDPELIAFGV 131
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
R+++A F+ARR G + + +A + SA W ++ + + A A
Sbjct 132 ARLGANRDLLAGFLARRLGIPSDGLRARVLADALSSAPFSALLWWADNDDGAPSRAAVEA 191
Query 186 FDVVGAGLD 194
D V G++
Sbjct 192 VDAVLRGVE 200
>gi|152968261|ref|YP_001364045.1| TetR family transcriptional regulator [Kineococcus radiotolerans
SRS30216]
gi|151362778|gb|ABS05781.1| transcriptional regulator, TetR family [Kineococcus radiotolerans
SRS30216]
Length=214
Score = 86.7 bits (213), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 56/171 (33%), Positives = 86/171 (51%), Gaps = 1/171 (0%)
Query 2 PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIP 61
P R GR +++ I VA+ELF GF + ++ +I AAG+++ + FRY+ SK +I
Sbjct 8 PTAPRRGRPPASSRAEIETVAVELFLTRGFEETTLAEITAAAGVSKTSFFRYFPSKASIV 67
Query 62 WGDFSTHLAQLQGLLDNIDSRIQ-LRDALRAALLAFNTFDESETIRHRKRMRVILQTPEL 120
W F + A LL+ R D +RAA++ + +R RV+ ++ EL
Sbjct 68 WWRFDEYTAGFARLLEESRDRGDATMDLVRAAVVGAVQRVIDDQGLWMQRFRVLEESSEL 127
Query 121 QAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWL 171
++ +A WRE +A FVA R G D +PQ VA + LS WL
Sbjct 128 RSGESQQWAEWREHVAAFVAHRHGLAAPDVVPQAVAGAVHAAYLSVLRRWL 178
>gi|330466754|ref|YP_004404497.1| putative transcriptional regulator [Verrucosispora maris AB-18-032]
gi|328809725|gb|AEB43897.1| putative transcriptional regulator [Verrucosispora maris AB-18-032]
Length=204
Score = 78.6 bits (192), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 50/147 (35%), Positives = 71/147 (49%), Gaps = 0/147 (0%)
Query 2 PHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIP 61
P R GR P + A++L+A G+ DDI+ A GI+ RTL R++ SK A+
Sbjct 7 PTPRRRGRPTVLDPEAVGTAALKLWAERGYGATGWDDISAATGISARTLMRHFPSKAALA 66
Query 62 WGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQ 121
W +L + I L DALRAA++A + D MRV+ + PEL
Sbjct 67 WVGVPAATRRLTETFRTLPLDIPLSDALRAAVVASVSDDALVLSAGGYWMRVVAEEPELA 126
Query 122 AYSMTMYAGWREVIAKFVARRSGGKTT 148
S YA W E +A+ +ARR G +
Sbjct 127 EASARAYAPWTEALAREIARRRPGAPS 153
>gi|325675952|ref|ZP_08155635.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
gi|325553190|gb|EGD22869.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
Length=216
Score = 74.7 bits (182), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 54/186 (30%), Positives = 84/186 (46%), Gaps = 20/186 (10%)
Query 17 HISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASK------NAIPWGDFSTHLA 70
ISDVAI+LFA HGF V+V+ IA GI+ R+ RY+ +K + WG+F
Sbjct 36 RISDVAIDLFAEHGFESVTVEQIAAEVGISARSFHRYFPAKEDAVIGDLTRWGEF----- 90
Query 71 QLQGLLDNIDSRIQLRDALRAALLAFNTF-----DESETIRHRKRMRVILQTPELQAYSM 125
+ D + SR L + +AF + E R ++ MRV+ T L+A ++
Sbjct 91 ----VRDGLASRPTDEPPLVSLRIAFEALLSRPRNAGEEERSKRTMRVLTSTASLRARNL 146
Query 126 TMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAA 185
+ GW +++ V R G + QT+ + L A W E V + L +
Sbjct 147 EKHLGWAKMLVPVVEARLNGDYAELRAQTLVQSALACFDIALSTWAESEGVDAVDLLRRS 206
Query 186 FDVVGA 191
F + A
Sbjct 207 FATLAA 212
Lambda K H
0.323 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 211830921192
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40