BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0724 Length=623 Score E Sequences producing significant alignments: (Bits) Value gi|15607864|ref|NP_215238.1| protease IV SppA [Mycobacterium tub... 1237 0.0 gi|339630792|ref|YP_004722434.1| endopeptidase IV [Mycobacterium... 1236 0.0 gi|340625745|ref|YP_004744197.1| putative protease IV SPPA [Myco... 1229 0.0 gi|289752771|ref|ZP_06512149.1| protease IV SppA [Mycobacterium ... 1215 0.0 gi|289446284|ref|ZP_06436028.1| protease IV sppA [Mycobacterium ... 1213 0.0 gi|339293749|gb|AEJ45860.1| protease IV SppA [Mycobacterium tube... 1188 0.0 gi|167968282|ref|ZP_02550559.1| protease IV sppA [Mycobacterium ... 1186 0.0 gi|289749231|ref|ZP_06508609.1| protease IV sppA [Mycobacterium ... 1116 0.0 gi|15840132|ref|NP_335169.1| protease IV [Mycobacterium tubercul... 1059 0.0 gi|240167730|ref|ZP_04746389.1| protease IV, Ssp [Mycobacterium ... 994 0.0 gi|183981078|ref|YP_001849369.1| protease IV, Ssp [Mycobacterium... 960 0.0 gi|15827982|ref|NP_302245.1| protease IV, signal peptide peptida... 938 0.0 gi|118616594|ref|YP_904926.1| protease IV, Ssp [Mycobacterium ul... 928 0.0 gi|296168584|ref|ZP_06850388.1| protease IV [Mycobacterium paras... 917 0.0 gi|41410286|ref|NP_963122.1| hypothetical protein MAP4188 [Mycob... 910 0.0 gi|118462440|ref|YP_883579.1| signal peptide peptidase SppA, 67K... 907 0.0 gi|289756812|ref|ZP_06516190.1| protease IV SppA [Mycobacterium ... 906 0.0 gi|289568669|ref|ZP_06448896.1| protease IV sppA [Mycobacterium ... 900 0.0 gi|342861819|ref|ZP_08718464.1| hypothetical protein MCOL_23135 ... 884 0.0 gi|254818384|ref|ZP_05223385.1| hypothetical protein MintA_00577... 870 0.0 gi|108798015|ref|YP_638212.1| signal peptide peptidase SppA, 67K... 853 0.0 gi|126433677|ref|YP_001069368.1| signal peptide peptidase SppA, ... 841 0.0 gi|118467630|ref|YP_885858.1| signal peptide peptidase SppA, 67K... 823 0.0 gi|333991946|ref|YP_004524560.1| protease IV Ssp [Mycobacterium ... 810 0.0 gi|315445955|ref|YP_004078834.1| signal peptide peptidase SppA, ... 795 0.0 gi|145225602|ref|YP_001136280.1| signal peptide peptidase SppA, ... 794 0.0 gi|120402354|ref|YP_952183.1| signal peptide peptidase SppA, 67K... 790 0.0 gi|169630869|ref|YP_001704518.1| protease IV SppA [Mycobacterium... 703 0.0 gi|289760851|ref|ZP_06520229.1| protease IV sppA [Mycobacterium ... 659 0.0 gi|308231618|ref|ZP_07663896.1| peptidase, S49 (protease IV) fam... 602 4e-170 gi|308231619|ref|ZP_07663897.1| signal peptide peptidase SppA, 3... 559 7e-157 gi|336460641|gb|EGO39532.1| ClpP class periplasmic serine protea... 493 3e-137 gi|333991950|ref|YP_004524564.1| signal peptide peptidase SppA 6... 388 2e-105 gi|284032927|ref|YP_003382858.1| signal peptide peptidase SppA, ... 372 1e-100 gi|271969371|ref|YP_003343567.1| signal peptide peptidase SppA, ... 364 2e-98 gi|269127810|ref|YP_003301180.1| signal peptide peptidase SppA, ... 362 9e-98 gi|296270823|ref|YP_003653455.1| signal peptide peptidase SppA, ... 362 1e-97 gi|72160983|ref|YP_288640.1| signal peptide peptidase A [Thermob... 361 2e-97 gi|23015704|ref|ZP_00055473.1| COG0616: Periplasmic serine prote... 357 4e-96 gi|108762546|ref|YP_635601.1| signal peptide peptidase SppA, 67K... 350 3e-94 gi|258652617|ref|YP_003201773.1| signal peptide peptidase SppA, ... 347 3e-93 gi|338531431|ref|YP_004664765.1| signal peptide peptidase SppA, ... 345 1e-92 gi|310825614|ref|YP_003957972.1| Signal peptide peptidase SppA, ... 345 1e-92 gi|115375108|ref|ZP_01462376.1| signal peptide peptidase SppA, 6... 345 1e-92 gi|83310697|ref|YP_420961.1| periplasmic serine protease [Magnet... 345 1e-92 gi|297559382|ref|YP_003678356.1| signal peptide peptidase SppA, ... 335 2e-89 gi|328873642|gb|EGG22009.1| hypothetical protein DFA_01898 [Dict... 332 2e-88 gi|83593953|ref|YP_427705.1| peptidase S49 [Rhodospirillum rubru... 331 3e-88 gi|336460640|gb|EGO39531.1| ClpP class periplasmic serine protea... 323 9e-86 gi|336115962|ref|YP_004570728.1| putative signal peptide peptida... 320 7e-85 >gi|15607864|ref|NP_215238.1| protease IV SppA [Mycobacterium tuberculosis H37Rv] gi|31791910|ref|NP_854403.1| protease IV SppA [Mycobacterium bovis AF2122/97] gi|121636646|ref|YP_976869.1| putative protease IV sppA (endopeptidase IV) [Mycobacterium bovis BCG str. Pasteur 1173P2] 31 more sequence titles Length=623 Score = 1237 bits (3201), Expect = 0.0, Method: Compositional matrix adjust. Identities = 623/623 (100%), Positives = 623/623 (100%), Gaps = 0/623 (0%) Query 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF Sbjct 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 Query 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV Sbjct 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 Query 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD Sbjct 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 Query 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV Sbjct 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 Query 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP Sbjct 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 Query 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG Sbjct 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 Query 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS Sbjct 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 Query 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP Sbjct 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 Query 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG Sbjct 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 Query 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV Sbjct 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 Query 601 GIVEQVEQTLSGASVLWLGESRL 623 GIVEQVEQTLSGASVLWLGESRL Sbjct 601 GIVEQVEQTLSGASVLWLGESRL 623 >gi|339630792|ref|YP_004722434.1| endopeptidase IV [Mycobacterium africanum GM041182] gi|339330148|emb|CCC25805.1| putative protease IV SPPA (endopeptidase IV) (signal peptide peptidase) [Mycobacterium africanum GM041182] Length=623 Score = 1236 bits (3198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/623 (99%), Positives = 623/623 (100%), Gaps = 0/623 (0%) Query 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF Sbjct 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 Query 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV Sbjct 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 Query 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD Sbjct 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 Query 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV Sbjct 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 Query 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP Sbjct 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 Query 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPS+AGG Sbjct 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSNAGG 360 Query 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS Sbjct 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 Query 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP Sbjct 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 Query 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG Sbjct 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 Query 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV Sbjct 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 Query 601 GIVEQVEQTLSGASVLWLGESRL 623 GIVEQVEQTLSGASVLWLGESRL Sbjct 601 GIVEQVEQTLSGASVLWLGESRL 623 >gi|340625745|ref|YP_004744197.1| putative protease IV SPPA [Mycobacterium canettii CIPT 140010059] gi|340003935|emb|CCC43069.1| putative protease IV SPPA (endopeptidase IV) (signal peptide peptidase) [Mycobacterium canettii CIPT 140010059] Length=623 Score = 1229 bits (3181), Expect = 0.0, Method: Compositional matrix adjust. Identities = 620/623 (99%), Positives = 621/623 (99%), Gaps = 0/623 (0%) Query 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 MPIFGGF VCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF Sbjct 1 MPIFGGFGVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 Query 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 NLRSVPPETTGFDPLTVLTGGGRPMALRDAV +IHRAAEDPRVAGLIARVQLPPSPAGAV Sbjct 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVDSIHRAAEDPRVAGLIARVQLPPSPAGAV 120 Query 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD Sbjct 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 Query 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV Sbjct 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 Query 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP Sbjct 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 Query 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG Sbjct 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 Query 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS Sbjct 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 Query 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP Sbjct 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 Query 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG Sbjct 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 Query 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV Sbjct 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 Query 601 GIVEQVEQTLSGASVLWLGESRL 623 GIVEQVEQTLSGASVLWLGESRL Sbjct 601 GIVEQVEQTLSGASVLWLGESRL 623 >gi|289752771|ref|ZP_06512149.1| protease IV SppA [Mycobacterium tuberculosis EAS054] gi|289693358|gb|EFD60787.1| protease IV SppA [Mycobacterium tuberculosis EAS054] Length=622 Score = 1215 bits (3144), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/623 (99%), Positives = 618/623 (99%), Gaps = 1/623 (0%) Query 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 MPIFG + RALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF Sbjct 1 MPIFGDGNLV-RALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 59 Query 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV Sbjct 60 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 119 Query 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD Sbjct 120 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 179 Query 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV Sbjct 180 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 239 Query 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP Sbjct 240 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 299 Query 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG Sbjct 300 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 359 Query 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS Sbjct 360 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 419 Query 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP Sbjct 420 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 479 Query 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG Sbjct 480 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 539 Query 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV Sbjct 540 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 599 Query 601 GIVEQVEQTLSGASVLWLGESRL 623 GIVEQVEQTLSGASVLWLGESRL Sbjct 600 GIVEQVEQTLSGASVLWLGESRL 622 >gi|289446284|ref|ZP_06436028.1| protease IV sppA [Mycobacterium tuberculosis CPHL_A] gi|289419242|gb|EFD16443.1| protease IV sppA [Mycobacterium tuberculosis CPHL_A] Length=613 Score = 1213 bits (3139), Expect = 0.0, Method: Compositional matrix adjust. Identities = 609/611 (99%), Positives = 611/611 (100%), Gaps = 0/611 (0%) Query 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF Sbjct 1 MPIFGGFCVCSRALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEF 60 Query 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV Sbjct 61 NLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAV 120 Query 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD Sbjct 121 QELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRD 180 Query 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV Sbjct 181 ALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGV 240 Query 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP Sbjct 241 DALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKP 300 Query 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG Sbjct 301 PRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGG 360 Query 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS Sbjct 361 DTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAAS 420 Query 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP Sbjct 421 GGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAP 480 Query 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG Sbjct 481 FTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGG 540 Query 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV Sbjct 541 LRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIV 600 Query 601 GIVEQVEQTLS 611 GIVEQVEQT++ Sbjct 601 GIVEQVEQTIA 611 >gi|339293749|gb|AEJ45860.1| protease IV SppA [Mycobacterium tuberculosis CCDC5079] gi|339297388|gb|AEJ49498.1| protease IV SppA [Mycobacterium tuberculosis CCDC5180] Length=602 Score = 1188 bits (3074), Expect = 0.0, Method: Compositional matrix adjust. Identities = 601/602 (99%), Positives = 602/602 (100%), Gaps = 0/602 (0%) Query 22 VNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG 81 +NMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG Sbjct 1 MNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG 60 Query 82 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE 141 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE Sbjct 61 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE 120 Query 142 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 201 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA Sbjct 121 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 180 Query 202 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 261 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG Sbjct 181 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 240 Query 262 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP 321 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP Sbjct 241 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP 300 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL 381 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL Sbjct 301 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL 360 Query 382 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG 441 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG Sbjct 361 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG 420 Query 442 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV 501 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV Sbjct 421 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV 480 Query 502 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 561 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR Sbjct 481 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 540 Query 562 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES 621 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES Sbjct 541 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES 600 Query 622 RL 623 RL Sbjct 601 RL 602 >gi|167968282|ref|ZP_02550559.1| protease IV sppA [Mycobacterium tuberculosis H37Ra] gi|254549685|ref|ZP_05140132.1| protease IV sppA [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|294996206|ref|ZP_06801897.1| protease IV sppA [Mycobacterium tuberculosis 210] 6 more sequence titles Length=600 Score = 1186 bits (3067), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/600 (100%), Positives = 600/600 (100%), Gaps = 0/600 (0%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR Sbjct 1 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY Sbjct 61 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL Sbjct 121 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI Sbjct 181 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI Sbjct 241 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 300 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV Sbjct 301 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 360 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI Sbjct 361 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 420 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER Sbjct 421 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 480 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV Sbjct 481 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 540 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 541 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 600 >gi|289749231|ref|ZP_06508609.1| protease IV sppA [Mycobacterium tuberculosis T92] gi|289689818|gb|EFD57247.1| protease IV sppA [Mycobacterium tuberculosis T92] Length=567 Score = 1116 bits (2886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 566/567 (99%), Positives = 567/567 (100%), Gaps = 0/567 (0%) Query 57 VLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSP 116 +LEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSP Sbjct 1 MLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSP 60 Query 117 AGAVQELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNAT 176 AGAVQELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNAT Sbjct 61 AGAVQELREAIAAFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNAT 120 Query 177 FLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSR 236 FLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSR Sbjct 121 FLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSR 180 Query 237 NIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSP 296 NIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSP Sbjct 181 NIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSP 240 Query 297 DEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPS 356 DEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPS Sbjct 241 DEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPS 300 Query 357 SAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGA 416 SAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGA Sbjct 301 SAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGA 360 Query 417 VAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWS 476 VAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWS Sbjct 361 VAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWS 420 Query 477 IDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVD 536 IDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVD Sbjct 421 IDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVD 480 Query 537 ELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLA 596 ELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLA Sbjct 481 ELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLA 540 Query 597 RSIVGIVEQVEQTLSGASVLWLGESRL 623 RSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 541 RSIVGIVEQVEQTLSGASVLWLGESRL 567 >gi|15840132|ref|NP_335169.1| protease IV [Mycobacterium tuberculosis CDC1551] gi|308370480|ref|ZP_07421698.2| protease IV sppA [Mycobacterium tuberculosis SUMu003] gi|308373552|ref|ZP_07432816.2| protease IV sppA [Mycobacterium tuberculosis SUMu005] 13 more sequence titles Length=539 Score = 1059 bits (2739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/539 (100%), Positives = 539/539 (100%), Gaps = 0/539 (0%) Query 85 MALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYP 144 MALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYP Sbjct 1 MALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYP 60 Query 145 GTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLF 204 GTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLF Sbjct 61 GTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLF 120 Query 205 TEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLID 264 TEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLID Sbjct 121 TEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLID 180 Query 265 RIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIP 324 RIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIP Sbjct 181 RIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIP 240 Query 325 GRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVD 384 GRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVD Sbjct 241 GRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVD 300 Query 385 SPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIG 444 SPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIG Sbjct 301 SPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIG 360 Query 445 VITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERV 504 VITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERV Sbjct 361 VITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERV 420 Query 505 AEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVS 564 AEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVS Sbjct 421 AEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVS 480 Query 565 YPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 YPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 481 YPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 539 >gi|240167730|ref|ZP_04746389.1| protease IV, Ssp [Mycobacterium kansasii ATCC 12478] Length=596 Score = 994 bits (2569), Expect = 0.0, Method: Compositional matrix adjust. Identities = 501/600 (84%), Positives = 545/600 (91%), Gaps = 4/600 (0%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M A L +P V+D+RAL RVDTARHHGVPNGCVLEFNLR++P ETTGFDPLT+L+GGGR Sbjct 1 MFALLSFLPGVDDVRALADRVDTARHHGVPNGCVLEFNLRNMPVETTGFDPLTILSGGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PMALRDAVAAIHRAAEDPRVAG+IARVQLPPSPAGAVQELREAIAAFSAVKPS+AWAETY Sbjct 61 PMALRDAVAAIHRAAEDPRVAGMIARVQLPPSPAGAVQELREAIAAFSAVKPSVAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAF E+W+QPSGSVGL+GFA+NA FLRDAL KAGIEA+ V RGEYKSAANL Sbjct 121 PGTLSYYLASAFREIWLQPSGSVGLIGFASNAMFLRDALDKAGIEAEVVTRGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTEDG+TDAHREAVTRML+SLQ QVW AVA+SR I VD L+ELADRAPLLRD+AV GLI Sbjct 181 FTEDGYTDAHREAVTRMLESLQSQVWHAVAESRRIDVDVLNELADRAPLLRDEAVASGLI 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+ YAR+AELVG+E S ES DEKPPRMYLARYA +AR RL PPVPSI Sbjct 241 DRIGFRDEVYARIAELVGIEGVSLES----VDTDEKPPRMYLARYAGTARSRLAPPVPSI 296 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGRRSKPTIAVVT+EGPIVNGRGGPQ LP GPSSAGGDTIAAALREVAADDS+SAIVLRV Sbjct 297 PGRRSKPTIAVVTVEGPIVNGRGGPQGLPFGPSSAGGDTIAAALREVAADDSISAIVLRV 356 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 DSPGGSVTASETIWREV RAR RGK VVASMGAVAASGGYYVSM ADAIVANPGTITGSI Sbjct 357 DSPGGSVTASETIWREVKRARRRGKHVVASMGAVAASGGYYVSMAADAIVANPGTITGSI 416 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GVITGKLVVRDLK+RLGVGS+ +RTNANADAWSID PFTP+Q+A REAEADLFY DFV R Sbjct 417 GVITGKLVVRDLKERLGVGSETLRTNANADAWSIDEPFTPEQRARREAEADLFYGDFVAR 476 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VAEGR ++T+AVDVVARGRVWTGADAL+RGLVDELGG RTAVRRAK+LAGLDEDT+VR+V Sbjct 477 VAEGRNLSTEAVDVVARGRVWTGADALERGLVDELGGFRTAVRRAKILAGLDEDTDVRLV 536 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 SYPGSSL D++ PR SSRPAAAS+PDA+G LL RSI G+VE +EQTLSGAS LWLG+SRL Sbjct 537 SYPGSSLLDLLLPRMSSRPAAASVPDAVGTLLIRSIAGVVEGIEQTLSGASALWLGQSRL 596 >gi|183981078|ref|YP_001849369.1| protease IV, Ssp [Mycobacterium marinum M] gi|183174404|gb|ACC39514.1| protease iv, Ssp [Mycobacterium marinum M] Length=600 Score = 960 bits (2481), Expect = 0.0, Method: Compositional matrix adjust. Identities = 482/601 (81%), Positives = 540/601 (90%), Gaps = 5/601 (0%) Query 24 MVAFLPSIPVV-EDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGG 82 ++ FLPS+ V +D+RAL RVDTARHHGVPNGC+LEFNLR++P E+ GFDPL +++GGG Sbjct 4 LLPFLPSLSSVGDDVRALAERVDTARHHGVPNGCILEFNLRTMPAESNGFDPLLIISGGG 63 Query 83 RPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAET 142 RPMALRDAVAA+HR AEDPRVAGLIARVQLPP+P GAVQELREAIAAFSAVKPS+AWAET Sbjct 64 RPMALRDAVAALHRGAEDPRVAGLIARVQLPPAPIGAVQELREAIAAFSAVKPSVAWAET 123 Query 143 YPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAAN 202 YPGTLSYYLA+AF E+WMQPSG GL+GFA+NA FLRDAL K GIEAQFVARGEYKSAA+ Sbjct 124 YPGTLSYYLATAFREIWMQPSGEAGLIGFASNAMFLRDALDKVGIEAQFVARGEYKSAAD 183 Query 203 LFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGL 262 LFTEDG+TDA+REAVTRML+SLQDQVWQAVA+SR I LDELAD+APLLRD+A++ GL Sbjct 184 LFTEDGYTDANREAVTRMLESLQDQVWQAVAQSRQIDAGVLDELADKAPLLRDEALSSGL 243 Query 263 IDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPS 322 IDRIGFRD+AYAR+AEL GVE SPES + +K PRM+LARYA +ARPRL PPVPS Sbjct 244 IDRIGFRDEAYARIAELAGVEGVSPESIDTA----DKLPRMHLARYAGTARPRLAPPVPS 299 Query 323 IPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLR 382 IPGRR KPTIAVV++EGPIVNGRGGPQ LPLGPSSAGGDTIA+ALREVAADD VSAIVLR Sbjct 300 IPGRRGKPTIAVVSVEGPIVNGRGGPQGLPLGPSSAGGDTIASALREVAADDEVSAIVLR 359 Query 383 VDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGS 442 VDSPGGSVTASETIWREV RARDRGKPVVASMG++AASGGYYVSMGADAIVANPGTITGS Sbjct 360 VDSPGGSVTASETIWREVQRARDRGKPVVASMGSIAASGGYYVSMGADAIVANPGTITGS 419 Query 443 IGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVE 502 IGVITGKLVVRDLKDRLGVGS+ +RTNANADAWSIDAPFT +Q+A REAEAD+FY+DFVE Sbjct 420 IGVITGKLVVRDLKDRLGVGSETLRTNANADAWSIDAPFTDEQRARREAEADMFYTDFVE 479 Query 503 RVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRI 562 RVA GR + T+ VD VARGRVWTGADAL+RGLVDELGG RTAVRRAKVLAGLDEDTEVR+ Sbjct 480 RVARGRNLRTEDVDAVARGRVWTGADALERGLVDELGGFRTAVRRAKVLAGLDEDTEVRL 539 Query 563 VSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESR 622 V YPGSSL D++ PR SSRP AAS+P+A+G L+ RS+ G V QVEQTL+GA+VLWLG SR Sbjct 540 VGYPGSSLLDLLWPRGSSRPVAASVPEAVGTLVVRSVAGAVGQVEQTLTGANVLWLGRSR 599 Query 623 L 623 Sbjct 600 F 600 >gi|15827982|ref|NP_302245.1| protease IV, signal peptide peptidase [Mycobacterium leprae TN] gi|221230459|ref|YP_002503875.1| protease IV, signal peptide peptidase [Mycobacterium leprae Br4923] gi|2344854|emb|CAB11456.1| endopeptidase IV [Mycobacterium leprae] gi|13093535|emb|CAC30793.1| protease IV, signal peptide peptidase [Mycobacterium leprae] gi|219933566|emb|CAR71935.1| protease IV, signal peptide peptidase [Mycobacterium leprae Br4923] Length=602 Score = 938 bits (2424), Expect = 0.0, Method: Compositional matrix adjust. Identities = 483/602 (81%), Positives = 526/602 (88%), Gaps = 2/602 (0%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M AFLP P ++D+RAL RV+TARHHG+PNGCVLE NLRS+PPETT FDP T++T GGR Sbjct 1 MSAFLPPFPGIDDVRALANRVNTARHHGIPNGCVLEVNLRSLPPETTSFDPFTIITRGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PMALR+AVAAIHRAA DPRVAG+IARVQL SP AVQELREA+A FSAVKPSLAWAETY Sbjct 61 PMALREAVAAIHRAAADPRVAGMIARVQLGASPPAAVQELREAVATFSAVKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVWMQPSGSVGLVGFA+NATFLRD L K GIEAQFVARGEYKSAANL Sbjct 121 PGTLSYYLASAFGEVWMQPSGSVGLVGFASNATFLRDVLAKVGIEAQFVARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTE GFTDAHREAV+RML+SLQ QVWQ +A+SR I AL+ LADRAPLLRDDAV GL+ Sbjct 181 FTEGGFTDAHREAVSRMLESLQGQVWQGIAESRRIDPAALNPLADRAPLLRDDAVASGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQ--TSPDEKPPRMYLARYASSARPRLTPPVP 321 DRIGFRD+AYAR+AELVG E +P SS Q T ++ PR+YL+RYAS+ R RL PP+P Sbjct 241 DRIGFRDEAYARIAELVGAESITPNSSEPQARTEANDGLPRLYLSRYASAGRSRLMPPMP 300 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL 381 IPGRRSKPT+ VVTLEGPIVNGRGGPQFLP G S+ GGDTIAAALREVAADDSVSAIVL Sbjct 301 LIPGRRSKPTVVVVTLEGPIVNGRGGPQFLPFGISTGGGDTIAAALREVAADDSVSAIVL 360 Query 382 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG 441 RV+SPGGSVTASETIWREV RARDRGKPVV SMGAVAASGGYYVS+GAD IVANPGTITG Sbjct 361 RVNSPGGSVTASETIWREVKRARDRGKPVVVSMGAVAASGGYYVSVGADEIVANPGTITG 420 Query 442 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV 501 SIGVITGKLV+RDLK RLGVGSD VRTNANADAWS + PFTP+Q HREAEADL Y+DF+ Sbjct 421 SIGVITGKLVIRDLKGRLGVGSDTVRTNANADAWSANVPFTPEQHTHREAEADLCYADFL 480 Query 502 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 561 ERVAEGR MTTDAVD VARGR+WTGADAL+RGLVDELGGL TAVRRAKVLAGLD D +VR Sbjct 481 ERVAEGRGMTTDAVDDVARGRIWTGADALERGLVDELGGLVTAVRRAKVLAGLDADVDVR 540 Query 562 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES 621 IVSYPGSSL DMVRPR SS+P AASLPDA+ LL RS+ GI+EQVEQ LSG VLWLGE Sbjct 541 IVSYPGSSLLDMVRPRASSQPGAASLPDAVATLLGRSVAGILEQVEQALSGVRVLWLGEY 600 Query 622 RL 623 R Sbjct 601 RF 602 >gi|118616594|ref|YP_904926.1| protease IV, Ssp [Mycobacterium ulcerans Agy99] gi|118568704|gb|ABL03455.1| protease iv, Ssp [Mycobacterium ulcerans Agy99] Length=600 Score = 928 bits (2398), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/604 (78%), Positives = 525/604 (87%), Gaps = 8/604 (1%) Query 24 MVAFLPSIP----VVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLT 79 M AFLP +P V +D+ AL RVDTARHHGVPNGC+LEFNLR++P E+ GFDP +++ Sbjct 1 MFAFLPFLPSLSSVGDDVHALAERVDTARHHGVPNGCILEFNLRTMPAESNGFDPFLIIS 60 Query 80 GGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAW 139 GGGRPMALRDAVAA+HR AEDPRV GLIARVQLPP+P GAVQ LREAIAAFSAVKPS+AW Sbjct 61 GGGRPMALRDAVAALHRGAEDPRVGGLIARVQLPPAPIGAVQALREAIAAFSAVKPSVAW 120 Query 140 AETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKS 199 AETYPGTLSYYLA+AF E+WMQPSG GL+GFA+NA FL DAL K GIEAQFVARGEYKS Sbjct 121 AETYPGTLSYYLATAFREIWMQPSGEAGLIGFASNAMFLCDALDKVGIEAQFVARGEYKS 180 Query 200 AANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVT 259 AA+LFTEDG+TDA+REAVTRML+SLQDQ W AVA+SR I LDELAD+APLLRD+A++ Sbjct 181 AADLFTEDGYTDANREAVTRMLESLQDQAWHAVAQSRQIDAGVLDELADKAPLLRDEALS 240 Query 260 CGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP 319 GLIDRIGFRD+AYAR+AEL VE SPES +K PRM+LARYA +ARPRL PP Sbjct 241 SGLIDRIGFRDEAYARIAELARVEGVSPES----IDIADKLPRMHLARYAGTARPRLAPP 296 Query 320 VPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAI 379 VPSIPGRR KPTIAVV++EGPIVNGRGGPQ LPLGPSSAGGDTIA+AL E AADD VSAI Sbjct 297 VPSIPGRRGKPTIAVVSVEGPIVNGRGGPQGLPLGPSSAGGDTIASALGETAADDEVSAI 356 Query 380 VLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTI 439 VLRVDSPGGSVTASETIWREV RARDRGK VVASMG++AASGGYYVSMGADAIVANPGTI Sbjct 357 VLRVDSPGGSVTASETIWREVQRARDRGKSVVASMGSIAASGGYYVSMGADAIVANPGTI 416 Query 440 TGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSD 499 TGSIGVITGKLVVRDLKDRLGVGS+ +RTNANADAWSIDAPFT +Q+A REAEAD+FY+D Sbjct 417 TGSIGVITGKLVVRDLKDRLGVGSETLRTNANADAWSIDAPFTDEQRARREAEADMFYTD 476 Query 500 FVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTE 559 F ERVA GR + T+ VD VARGRVWTGADAL+RGLVDELGG RTAV RAKVLAGLDEDTE Sbjct 477 FAERVARGRNLRTEDVDAVARGRVWTGADALERGLVDELGGFRTAVPRAKVLAGLDEDTE 536 Query 560 VRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLG 619 VR V YPGS L D++ PR SSRP AAS+P+A+GAL+ RS+ G V QVEQTL+GA+VLWLG Sbjct 537 VRPVGYPGSLLLDLLWPRGSSRPVAASVPEAVGALVVRSVAGAVGQVEQTLTGANVLWLG 596 Query 620 ESRL 623 SR Sbjct 597 RSRF 600 >gi|296168584|ref|ZP_06850388.1| protease IV [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896647|gb|EFG76286.1| protease IV [Mycobacterium parascrofulaceum ATCC BAA-614] Length=594 Score = 917 bits (2371), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/600 (77%), Positives = 520/600 (87%), Gaps = 6/600 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M AFLPSIP V+D+RAL RVDTARHHGVPNGCVLE +LRS PPETTGFDPL +LTGG R Sbjct 1 MFAFLPSIPGVDDVRALAERVDTARHHGVPNGCVLELDLRSAPPETTGFDPLAILTGG-R 59 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PMALRDAVAA+HRAAEDPRVAGLIARVQL SP AVQELREAIAAFSA KPSLAWAETY Sbjct 60 PMALRDAVAAVHRAAEDPRVAGLIARVQLAASPPAAVQELREAIAAFSAAKPSLAWAETY 119 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAF EVWMQPSGSVGL+GFA+N TFLRDA KAGIE QFVARG+YKS AN Sbjct 120 PGTLSYYLASAFREVWMQPSGSVGLIGFASNETFLRDAFDKAGIEPQFVARGQYKSWANR 179 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTE GFT AHREAVTRML+SLQ+Q W+A+A+SR + ALD LADRAPLLRDDAV GL+ Sbjct 180 FTEHGFTTAHREAVTRMLESLQEQTWRAIAQSRKLDPGALDTLADRAPLLRDDAVAAGLL 239 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+AYAR+AE+ G S + S PPR+YL+RYA ++RPRL P P + Sbjct 240 DRIGFRDEAYARIAEMAGAPADSADDSDDTA-----PPRLYLSRYAGASRPRLAAPKPPV 294 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGR+ KPT+AV+TL+G IV+GRGGPQFLP G ++AGGDTI AALRE AADDSVSAIVLRV Sbjct 295 PGRKPKPTLAVITLDGMIVDGRGGPQFLPFGAATAGGDTIGAALREAAADDSVSAIVLRV 354 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 +SPGG++TASE+IWREV RAR RGKPVVASMGAVAASGGYYVSMGADAIVANP T+TGSI Sbjct 355 NSPGGTITASESIWREVTRARKRGKPVVASMGAVAASGGYYVSMGADAIVANPATVTGSI 414 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GVITGKLV+RDL +RLGVGSD VRTNANADAWSIDAPFTP+Q+AHREAEADLFY+DFV+R Sbjct 415 GVITGKLVIRDLLERLGVGSDTVRTNANADAWSIDAPFTPEQRAHREAEADLFYADFVQR 474 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VAE R +TT+A + VA+GR+WTGADALDRGLVDELGG R AVRRAKVLAGLDED++VRIV Sbjct 475 VAEARNLTTEAAESVAQGRIWTGADALDRGLVDELGGFRAAVRRAKVLAGLDEDSDVRIV 534 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 +YP SSL DMVRPR SS+PAAASLPDA+GALL R++ ++ VE+T+SG SVLW G SR Sbjct 535 AYPSSSLLDMVRPRASSQPAAASLPDALGALLGRTVTSFLDNVERTMSGVSVLWPGPSRF 594 >gi|41410286|ref|NP_963122.1| hypothetical protein MAP4188 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41399120|gb|AAS06738.1| SppA [Mycobacterium avium subsp. paratuberculosis K-10] Length=595 Score = 910 bits (2353), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/604 (76%), Positives = 520/604 (87%), Gaps = 13/604 (2%) Query 24 MVAFLPSIPVV----EDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLT 79 M A L SIP + +++RAL GRVDTARHHGVPNGCVLE +LRS+PPET+GFDPL ++T Sbjct 1 MFAVLSSIPGLSKGADEIRALAGRVDTARHHGVPNGCVLELDLRSMPPETSGFDPLALVT 60 Query 80 GGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAW 139 GG RP +LRD V AIHRAAEDPRVAGLIARVQL PSP+ AVQELREAI AF+A KPSLAW Sbjct 61 GGSRPASLRDTVDAIHRAAEDPRVAGLIARVQLAPSPSAAVQELREAIVAFTAAKPSLAW 120 Query 140 AETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKS 199 AETYPGTLSYYLASAFGE+WMQP GSVGL+GFA+NATFLRDAL KAGIEAQFVARGEYKS Sbjct 121 AETYPGTLSYYLASAFGEIWMQPGGSVGLIGFASNATFLRDALDKAGIEAQFVARGEYKS 180 Query 200 AANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVT 259 A N FTE GFT+AHREAVTRMLDS+Q+QVWQAVA+SR + DALD LADRAPLLR DA+ Sbjct 181 AVNRFTEHGFTEAHREAVTRMLDSVQEQVWQAVAESRKLDTDALDALADRAPLLRQDALD 240 Query 260 CGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP 319 GL+DRIGFRDQAY R+AELVGV+ SPD +PPR+Y++RYA +AR RL+PP Sbjct 241 SGLVDRIGFRDQAYDRIAELVGVQ---------DVSPDTEPPRLYVSRYAGAARSRLSPP 291 Query 320 VPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAI 379 VPS+PGRR PT+AV+ ++G +V+GRGGP FLP G ++ G DTIA ALRE AADD+VSAI Sbjct 292 VPSLPGRRRPPTVAVINVDGTLVDGRGGPHFLPFGAATVGSDTIAPALREAAADDAVSAI 351 Query 380 VLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTI 439 VLRV+SPGGSVTASET+WREV RAR+RGKPVVASMGAVAASGGYYVS+ ADAIVANP TI Sbjct 352 VLRVNSPGGSVTASETLWREVKRARERGKPVVASMGAVAASGGYYVSVAADAIVANPATI 411 Query 440 TGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSD 499 TGSIGVITGKLV+RDL RLGVGSD VRTNANADAWSIDAPFTP+Q+AHREAEADL Y+D Sbjct 412 TGSIGVITGKLVIRDLLGRLGVGSDTVRTNANADAWSIDAPFTPEQRAHREAEADLVYTD 471 Query 500 FVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTE 559 FV RVAEGR +TTDAV+ VARGRVWTGADA +RGLVDELGG R AVRRAK+LAGLDED + Sbjct 472 FVSRVAEGRNLTTDAVERVARGRVWTGADAHERGLVDELGGFRIAVRRAKILAGLDEDAD 531 Query 560 VRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLG 619 VRIV+YP SL D++RPR SS+PAA SLPDA+GAL +++ I++ VE++ SGAS LWLG Sbjct 532 VRIVTYPSGSLLDVLRPRASSQPAAVSLPDALGALTVKTLGAILDNVERSCSGASALWLG 591 Query 620 ESRL 623 SRL Sbjct 592 PSRL 595 >gi|118462440|ref|YP_883579.1| signal peptide peptidase SppA, 67K type [Mycobacterium avium 104] gi|254776880|ref|ZP_05218396.1| signal peptide peptidase SppA, 67K type [Mycobacterium avium subsp. avium ATCC 25291] gi|118163727|gb|ABK64624.1| signal peptide peptidase SppA, 67K type [Mycobacterium avium 104] Length=595 Score = 907 bits (2344), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/604 (76%), Positives = 518/604 (86%), Gaps = 13/604 (2%) Query 24 MVAFLPSIPVV----EDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLT 79 M A L SIP + +++RAL GRVDTARHHGVPNGCVLE +LRS+PPET+GFDPL ++T Sbjct 1 MFAVLSSIPGLSKGADEIRALAGRVDTARHHGVPNGCVLELDLRSMPPETSGFDPLALVT 60 Query 80 GGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAW 139 GG R +LRD V AIHRAAEDPRVAGLIARVQL PSP+ AVQELREAI AF+A KPSLAW Sbjct 61 GGSRSASLRDTVDAIHRAAEDPRVAGLIARVQLAPSPSAAVQELREAIVAFTAAKPSLAW 120 Query 140 AETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKS 199 AETYPGTLSYYLASAFGE+WMQP GSVGL+GFA+NATFLRDAL KAGIEAQFVARGEYKS Sbjct 121 AETYPGTLSYYLASAFGEIWMQPGGSVGLIGFASNATFLRDALDKAGIEAQFVARGEYKS 180 Query 200 AANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVT 259 A N FTE GFT+AHREAVTRMLDS+Q+QVWQAVA+SR + DALD LADRAPLLR DA+ Sbjct 181 AVNRFTEHGFTEAHREAVTRMLDSVQEQVWQAVAESRKLDTDALDALADRAPLLRQDALD 240 Query 260 CGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP 319 GL+DRIGFRDQAY R+AELVGV+ SPD +PPR+Y++RYA +AR RL+PP Sbjct 241 SGLVDRIGFRDQAYDRIAELVGVQ---------DVSPDTEPPRLYVSRYAGAARSRLSPP 291 Query 320 VPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAI 379 VPS+PGRR PT+AV+ ++G +V+GRGGP FLP G ++ G DTIA ALRE AADD+VSAI Sbjct 292 VPSLPGRRRPPTVAVINVDGTLVDGRGGPHFLPFGAATVGSDTIAPALREAAADDAVSAI 351 Query 380 VLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTI 439 VLRV+SPGGSVTASET+WREV RAR+RGKPVVASMGAVAASGGYYVS+ ADAIVANP TI Sbjct 352 VLRVNSPGGSVTASETLWREVKRARERGKPVVASMGAVAASGGYYVSVAADAIVANPATI 411 Query 440 TGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSD 499 TGSIGVITGKLV+RDL RLGVGSD VRTNANADAWSIDAPFTP+Q+AHREAEADL Y+D Sbjct 412 TGSIGVITGKLVIRDLLGRLGVGSDTVRTNANADAWSIDAPFTPEQRAHREAEADLVYTD 471 Query 500 FVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTE 559 FV RVAEGR +TTDAV+ VARGRVWTGADA +RGLVDELGG R AVRRAK+LAGLDED + Sbjct 472 FVSRVAEGRNLTTDAVERVARGRVWTGADAHERGLVDELGGFRIAVRRAKILAGLDEDAD 531 Query 560 VRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLG 619 VRIV+YP SL D++RPR SS+PAA SLPDA+GAL + + I++ VE++ SGAS LWLG Sbjct 532 VRIVTYPSGSLLDVLRPRASSQPAAVSLPDALGALTVKILGAILDNVERSCSGASALWLG 591 Query 620 ESRL 623 SRL Sbjct 592 PSRL 595 >gi|289756812|ref|ZP_06516190.1| protease IV SppA [Mycobacterium tuberculosis T85] gi|289712376|gb|EFD76388.1| protease IV SppA [Mycobacterium tuberculosis T85] Length=466 Score = 906 bits (2342), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/463 (99%), Positives = 461/463 (99%), Gaps = 0/463 (0%) Query 161 QPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRM 220 P GSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRM Sbjct 4 NPRGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRM 63 Query 221 LDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELV 280 LDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELV Sbjct 64 LDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELV 123 Query 281 GVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGP 340 GVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGP Sbjct 124 GVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGP 183 Query 341 IVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREV 400 IVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREV Sbjct 184 IVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREV 243 Query 401 ARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLG 460 ARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLG Sbjct 244 ARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLG 303 Query 461 VGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVAR 520 VGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVAR Sbjct 304 VGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVAR 363 Query 521 GRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSS 580 GRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSS Sbjct 364 GRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSS 423 Query 581 RPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 RPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 424 RPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 466 Score = 49.3 bits (116), Expect = 0.002, Method: Compositional matrix adjust. Identities = 58/217 (27%), Positives = 89/217 (42%), Gaps = 14/217 (6%) Query 72 FDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQEL-REAIAAF 130 F PL + GG +A AA+ A D V+ ++ RV P A + + RE A Sbjct 193 FLPLGPSSAGGDTIA-----AALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 247 Query 131 SAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQ 190 KP +A + YY++ + P G +G T +RD + G+ + Sbjct 248 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 307 Query 191 FVARGEYKSAANL---FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELA 247 V A ++ FT D AHREA D + VA+ R + DA+D +A Sbjct 308 AVRTNANADAWSIDAPFTPD--QQAHREAEA---DLFYSDFVERVAEGRKMTTDAVDVVA 362 Query 248 DRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEK 284 DA+ GL+D +G A R L G+++ Sbjct 363 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDE 399 >gi|289568669|ref|ZP_06448896.1| protease IV sppA [Mycobacterium tuberculosis T17] gi|289542423|gb|EFD46071.1| protease IV sppA [Mycobacterium tuberculosis T17] Length=458 Score = 900 bits (2325), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/458 (99%), Positives = 458/458 (100%), Gaps = 0/458 (0%) Query 166 VGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQ 225 +GLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQ Sbjct 1 MGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQ 60 Query 226 DQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKG 285 DQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKG Sbjct 61 DQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKG 120 Query 286 SPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR 345 SPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR Sbjct 121 SPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR 180 Query 346 GGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARD 405 GGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARD Sbjct 181 GGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARD 240 Query 406 RGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDA 465 RGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDA Sbjct 241 RGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDA 300 Query 466 VRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWT 525 VRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWT Sbjct 301 VRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWT 360 Query 526 GADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAA 585 GADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAA Sbjct 361 GADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAA 420 Query 586 SLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 SLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 421 SLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 458 Score = 48.5 bits (114), Expect = 0.003, Method: Compositional matrix adjust. Identities = 58/217 (27%), Positives = 89/217 (42%), Gaps = 14/217 (6%) Query 72 FDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQEL-REAIAAF 130 F PL + GG +A AA+ A D V+ ++ RV P A + + RE A Sbjct 185 FLPLGPSSAGGDTIA-----AALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 239 Query 131 SAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQ 190 KP +A + YY++ + P G +G T +RD + G+ + Sbjct 240 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 299 Query 191 FVARGEYKSAANL---FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELA 247 V A ++ FT D AHREA D + VA+ R + DA+D +A Sbjct 300 AVRTNANADAWSIDAPFTPD--QQAHREAEA---DLFYSDFVERVAEGRKMTTDAVDVVA 354 Query 248 DRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEK 284 DA+ GL+D +G A R L G+++ Sbjct 355 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDE 391 >gi|342861819|ref|ZP_08718464.1| hypothetical protein MCOL_23135 [Mycobacterium colombiense CECT 3035] gi|342130636|gb|EGT83940.1| hypothetical protein MCOL_23135 [Mycobacterium colombiense CECT 3035] Length=591 Score = 884 bits (2284), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/600 (75%), Positives = 522/600 (87%), Gaps = 9/600 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M AFLPSIP V ++RAL GRVDTARHHGVPNGCVLE +LRS+PPET+GFDPL ++TGG R Sbjct 1 MFAFLPSIPGVGEVRALAGRVDTARHHGVPNGCVLELDLRSMPPETSGFDPLAIITGGSR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P+ALRD VAAIHRAAED RVAGLIARVQL SP+ AVQELREAI F+A KPSLAWAETY Sbjct 61 PVALRDMVAAIHRAAEDSRVAGLIARVQLGASPSAAVQELREAIVEFTAAKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVWMQP+GS+GL+GFA+NATFLRDA KAGIEAQFVARGEYKSA N Sbjct 121 PGTLSYYLASAFGEVWMQPAGSLGLIGFASNATFLRDAFDKAGIEAQFVARGEYKSAVNR 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTE GFT+AHREAVTRML+SLQ+QVW+AVA+SR + LD LADRAPLLR++AV+ GL+ Sbjct 181 FTEHGFTEAHREAVTRMLESLQEQVWEAVARSRKLDTGVLDALADRAPLLREEAVSSGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+AY R+AELVGV+ S E++ PPR+YL+RYA +AR RL+PP P + Sbjct 241 DRIGFRDEAYDRIAELVGVQDVSEENA---------PPRLYLSRYAGAARSRLSPPAPPV 291 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGRR KP +AVV ++G IV+GRGGPQFLP G S+ G DTIA ALRE AAD+SVSAIVLRV Sbjct 292 PGRRPKPKVAVVNIDGTIVDGRGGPQFLPFGASTVGSDTIAPALREAAADESVSAIVLRV 351 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 +SPGGSVTASET+WREV RAR GKPVVASMGAVAASGGYY+++ ADAIVA+P TITGSI Sbjct 352 NSPGGSVTASETLWREVKRARKLGKPVVASMGAVAASGGYYIAVAADAIVASPATITGSI 411 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GVITGKLV+RDL +RLGVG D+VRTNANAD+WSI+APFTP+Q+AHREAEADL Y+DF+ER Sbjct 412 GVITGKLVIRDLLERLGVGLDSVRTNANADSWSIEAPFTPEQRAHREAEADLVYADFLER 471 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VA+GR +TT+AVD VARGRVWTGADA +RGLVDELGG RTA+RRAK+LAGLDEDT+VR+V Sbjct 472 VADGRNLTTEAVDRVARGRVWTGADARERGLVDELGGFRTALRRAKILAGLDEDTDVRLV 531 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 +YPG SL DM+RPR SS+PAAAS+PDA+ ALL R+I G+++ VE++ +GAS LW G RL Sbjct 532 TYPGGSLLDMLRPRASSQPAAASVPDALAALLGRTIGGVLDSVERSYTGASALWPGPWRL 591 >gi|254818384|ref|ZP_05223385.1| hypothetical protein MintA_00577 [Mycobacterium intracellulare ATCC 13950] Length=595 Score = 870 bits (2248), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/604 (75%), Positives = 523/604 (87%), Gaps = 13/604 (2%) Query 24 MVAFLPSIPVV----EDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLT 79 M AFLPSIP + +++RAL RVDTARHHGVPNGCVLE +LRS+PPET+GFDPL ++T Sbjct 1 MFAFLPSIPGLSKGADEVRALADRVDTARHHGVPNGCVLELDLRSMPPETSGFDPLAMIT 60 Query 80 GGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAW 139 GG RP++LRD V+AI+RAAEDPRVAGLIARVQL SP+ AVQELREAI AF+A KPSLAW Sbjct 61 GGSRPVSLRDTVSAIYRAAEDPRVAGLIARVQLTASPSAAVQELREAIVAFTAAKPSLAW 120 Query 140 AETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKS 199 AETYPGTLSYYLASAFGEVWMQP+GSVGL+GFA+NATFLRDA KAGIEA+ VARGEYKS Sbjct 121 AETYPGTLSYYLASAFGEVWMQPAGSVGLIGFASNATFLRDAFDKAGIEAEVVARGEYKS 180 Query 200 AANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVT 259 AAN FTE GFT+AHREAVTRML+S+++QVW+AV SR + ALD LADRAPLLR++AV+ Sbjct 181 AANRFTEHGFTEAHREAVTRMLESIREQVWEAVGTSRKLDAAALDALADRAPLLREEAVS 240 Query 260 CGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP 319 GL+DRIGFRD+AY R+AELVGV+ S E++ PPR+YL+RYA +AR RL PP Sbjct 241 SGLVDRIGFRDEAYDRIAELVGVKDVSEENA---------PPRLYLSRYAGAARSRLIPP 291 Query 320 VPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAI 379 PS+PGRR KPT+AV+ ++G IV+GRGGPQFLP G S+ G DTIA ALRE AADDSVSAI Sbjct 292 APSVPGRRPKPTVAVINVDGTIVDGRGGPQFLPFGTSTVGSDTIAPALREAAADDSVSAI 351 Query 380 VLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTI 439 V+RV+SPGGSVTASET+WREV +AR RGKPVVASMG+VAASGGYY+++ ADA+VA+P TI Sbjct 352 VVRVNSPGGSVTASETLWREVKKARKRGKPVVASMGSVAASGGYYIAVAADAVVASPATI 411 Query 440 TGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSD 499 TGSIGV+TGKLV+RDL RLGVGSD VRTNANADAW+ID PFTP+Q+AHREAEADL Y+D Sbjct 412 TGSIGVLTGKLVIRDLLGRLGVGSDTVRTNANADAWAIDTPFTPEQRAHREAEADLLYAD 471 Query 500 FVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTE 559 FV RVA+GR +T DAVD VARGRVWTGADAL+RGLVDELGG RTA+RRAK+LAGLDED + Sbjct 472 FVARVADGRNLTKDAVDRVARGRVWTGADALERGLVDELGGFRTALRRAKILAGLDEDAD 531 Query 560 VRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLG 619 VRIV+YPG SL DM+RPR SS+PAAASLPDA+GALL R+I GIV+ VE+++SGAS LW G Sbjct 532 VRIVTYPGGSLLDMLRPRASSQPAAASLPDALGALLGRTIGGIVDNVERSVSGASALWAG 591 Query 620 ESRL 623 RL Sbjct 592 PWRL 595 >gi|108798015|ref|YP_638212.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. MCS] gi|119867110|ref|YP_937062.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. KMS] gi|108768434|gb|ABG07156.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. MCS] gi|119693199|gb|ABL90272.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. KMS] Length=593 Score = 853 bits (2204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 434/600 (73%), Positives = 504/600 (84%), Gaps = 7/600 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M AFLP IP +D+RALV RVDTARH G+PNGCVLE +L SVPPET+GFDPL +++ GGR Sbjct 1 MFAFLPGIPGADDVRALVRRVDTARHKGIPNGCVLELDLMSVPPETSGFDPLAMISAGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PM LR VAAIHRAA+D RVAGLIARVQ+ +PA VQELREAIAAF A KPS+AWAETY Sbjct 61 PMVLRQVVAAIHRAADDDRVAGLIARVQISAAPAAPVQELREAIAAFGAKKPSVAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAF EVWMQPSG+VGLVGFAT+A FLRDAL KAGI+AQF ARGEYKSAANL Sbjct 121 PGTLSYYLASAFREVWMQPSGTVGLVGFATSALFLRDALDKAGIQAQFTARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FT+D +T+ HREA +R+++SL QV AVA+SR + D +D LAD+APLLRD AV GL+ Sbjct 181 FTQDSYTEPHREADSRLIESLNQQVLTAVAESRKLNPDDIDALADKAPLLRDAAVGGGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+AYAR+AEL G E +P+++ SPD PPR++L+RYA + P P SI Sbjct 241 DRIGFRDEAYARVAELAGAEGVTPQNT---DSPD-APPRLFLSRYARATAPGGGP---SI 293 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGR++KPTIAVVTL GPIV+GRGGP PLG SSAGGDTI AALRE AAD VSAIVLRV Sbjct 294 PGRKAKPTIAVVTLHGPIVSGRGGPGLSPLGNSSAGGDTITAALREAAADKDVSAIVLRV 353 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 +SPGGSVT SETIWREV R R+ G PVVASMGAVAASGGYYVSMGADAIVANPGTITGSI Sbjct 354 ESPGGSVTGSETIWREVLRTREGGTPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 413 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GV+TGKLV R+LKDRLGVGSD+VRTNANADAWS ++PFT +QQAH EAEADLFY+DFVER Sbjct 414 GVVTGKLVARELKDRLGVGSDSVRTNANADAWSANSPFTDEQQAHVEAEADLFYTDFVER 473 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VA+GR ++ D V VARGRVWTGADA DRGLVDELGGLRTA+ RAKVLAGL+ DT+VRIV Sbjct 474 VADGRGLSVDEVAEVARGRVWTGADAKDRGLVDELGGLRTAIDRAKVLAGLEPDTDVRIV 533 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 YP SSL D++RP+ SS+PAAASLPDA+G L+ RS+V +++Q E+T+SG + +WLG+ R Sbjct 534 GYPASSLLDLLRPKQSSQPAAASLPDALGVLVGRSVVSLIDQAERTVSGVNAMWLGDYRF 593 >gi|126433677|ref|YP_001069368.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. JLS] gi|126233477|gb|ABN96877.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. JLS] Length=593 Score = 841 bits (2173), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/600 (73%), Positives = 506/600 (85%), Gaps = 7/600 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M AFLP IP +D+RALV RVDTARH G+PNGCVLE +L SVPPET+GFDPL +++ GGR Sbjct 1 MFAFLPGIPGADDVRALVRRVDTARHKGIPNGCVLELDLMSVPPETSGFDPLAMISAGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 PM LR VAAIHRAA+D RVAGLIARVQ+ +PA VQELREAIAAFSA KPS+AWAETY Sbjct 61 PMVLRQVVAAIHRAADDDRVAGLIARVQISAAPAAPVQELREAIAAFSAKKPSVAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAF EVWMQPSG+VGLVGFAT+A FLRDAL KAGI+AQF ARGEYKSAANL Sbjct 121 PGTLSYYLASAFREVWMQPSGTVGLVGFATSALFLRDALDKAGIQAQFTARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FT+D +T+ HREA +R+++SL QV AVA+SR + D +D LAD+APLLRD AV GL+ Sbjct 181 FTQDSYTEPHREADSRLIESLNQQVLTAVAESRKLNPDDIDALADKAPLLRDAAVDGGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+AYAR+AEL G E +P+++ SPD PPR++L+RYA + P P SI Sbjct 241 DRIGFRDEAYARVAELAGAEGVTPQNT---DSPD-APPRLFLSRYARATAPGGGP---SI 293 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGR++KPTIAVVTL GPIV+GRGGP PLG SSAGGDTIAAALRE AAD VSAIVLRV Sbjct 294 PGRKAKPTIAVVTLHGPIVSGRGGPGLSPLGNSSAGGDTIAAALREAAADKDVSAIVLRV 353 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 +SPGGSVT SETIWREV R R+ G PVVASMGAVAASGGYYVSMGADAIVANPGTITGSI Sbjct 354 ESPGGSVTGSETIWREVLRTREGGTPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 413 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GV+TGKLV R+LKDRLGVGSD+VRTNANADAWS ++PFT +QQAH EAEADLFY+DFVER Sbjct 414 GVVTGKLVARELKDRLGVGSDSVRTNANADAWSANSPFTDEQQAHVEAEADLFYTDFVER 473 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 VA+GR ++ D V VARGRVWTGADA DRGLVDELGGLRTA+ RAKVLAGL+ DT+VRIV Sbjct 474 VADGRGLSVDEVAEVARGRVWTGADAKDRGLVDELGGLRTAIDRAKVLAGLEPDTDVRIV 533 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 YP SSL D++RP+ SS+PAAASLPDA+G L+ RS+V +++Q E+T+SG + +WLG+ R Sbjct 534 GYPASSLLDLLRPKQSSQPAAASLPDALGVLVGRSVVSLIDQAERTVSGVNAMWLGDYRF 593 >gi|118467630|ref|YP_885858.1| signal peptide peptidase SppA, 67K type [Mycobacterium smegmatis str. MC2 155] gi|118168917|gb|ABK69813.1| signal peptide peptidase SppA, 67K type [Mycobacterium smegmatis str. MC2 155] Length=594 Score = 823 bits (2127), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/600 (70%), Positives = 502/600 (84%), Gaps = 6/600 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M FLP IP +DLRALV RVDTARH+GVP+GCVLE +L S+PPETTGFDPL ++ GGGR Sbjct 1 MFGFLPGIPGQDDLRALVRRVDTARHNGVPDGCVLELDLMSIPPETTGFDPLAMIAGGGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P+ LR AVAAIHRAAED RVAGLIARVQLP + G VQELR+AI AF KP++AWAETY Sbjct 61 PLVLRQAVAAIHRAAEDDRVAGLIARVQLPAAAPGPVQELRDAIVAFGERKPTVAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGT+SYYLASAF E+WMQP+GSVGL+GFATNATFLRDAL KAGIEAQF+ARGEYKSAAN+ Sbjct 121 PGTMSYYLASAFREIWMQPAGSVGLIGFATNATFLRDALDKAGIEAQFIARGEYKSAANV 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTE +T+ HREA R+++SLQ+QVWQ +A+SR + D ++ LAD+APLLR+ AVT GL+ Sbjct 181 FTEGSYTEPHREADARLIESLQEQVWQGIAQSRGLDPDTINTLADQAPLLREAAVTAGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSI 323 DRIGFRD+AY R+ EL G PE++ + D+ PPR++L+RYA + P+ PP+PS+ Sbjct 241 DRIGFRDEAYKRIGELAG----GPENTDADH--DDAPPRLFLSRYAKATAPKPAPPLPSL 294 Query 324 PGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRV 383 PGR+SKPTIAVVTL G IV+GRGGPQ LP G SSAGGDTIAAALRE AA+D V+A+VLRV Sbjct 295 PGRKSKPTIAVVTLHGAIVSGRGGPQPLPFGRSSAGGDTIAAALREAAANDDVAAVVLRV 354 Query 384 DSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSI 443 DSPGGSVT SET+WREV R RD GKPVVASMGAVAASGGYYVSM AD IVAN GTITGSI Sbjct 355 DSPGGSVTGSETVWREVVRTRDAGKPVVASMGAVAASGGYYVSMAADEIVANAGTITGSI 414 Query 444 GVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVER 503 GV+TGK V R+LKD+LGVGSDAVRTNANADAWS +APFT +Q A EAEADL Y DFVER Sbjct 415 GVLTGKFVSRELKDKLGVGSDAVRTNANADAWSTNAPFTDEQHARVEAEADLLYRDFVER 474 Query 504 VAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIV 563 AEGRK+ + ++ +ARGRVWTG+DA +RGLVD +GGLR AV RAKVLAG DED + R+V Sbjct 475 AAEGRKLPIEEMESLARGRVWTGSDAKERGLVDHVGGLRAAVTRAKVLAGFDEDADARVV 534 Query 564 SYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 +YPGSS DM+RP+PSS+PAAASLP+A+ ALL +S++G+++Q E++++GAS LWLGE R Sbjct 535 AYPGSSWLDMLRPKPSSQPAAASLPEALAALLGKSVIGVLDQAERSMTGASALWLGEYRF 594 >gi|333991946|ref|YP_004524560.1| protease IV Ssp [Mycobacterium sp. JDM601] gi|333487914|gb|AEF37306.1| protease IV Ssp [Mycobacterium sp. JDM601] Length=597 Score = 810 bits (2093), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/602 (71%), Positives = 495/602 (83%), Gaps = 9/602 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M + LP +P ++DLR + R+DTARH GVPNG VLE +L+++P ET GFDPL ++ G + Sbjct 1 MFSLLPGVPGLDDLRGVARRIDTARHRGVPNGVVLELDLQTMPHETGGFDPLALIRFGAQ 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P LRD V AIHRAA+DPRVAGLIARVQL + AG VQELR AIA F+AVKPSLAWAETY Sbjct 61 PPVLRDLVDAIHRAADDPRVAGLIARVQLSAAAAGPVQELRAAIAEFTAVKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVW+QPSG VGL+GFATNATFLR AL KAGIEAQFVARGEYKSAANL Sbjct 121 PGTLSYYLASAFGEVWLQPSGMVGLIGFATNATFLRTALGKAGIEAQFVARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FT+D +TDAHREA T +++SL QV AVA+SRN+ A+D LADRAPLLRDDAV GLI Sbjct 181 FTQDSYTDAHREADTALVESLHTQVRAAVAESRNLDAGAVDALADRAPLLRDDAVGGGLI 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARY--ASSARPRL-TPPV 320 DRIGFRD+AY R+AELV GSP + + E PPR+YL RY A++ P + P + Sbjct 241 DRIGFRDEAYDRIAELV-AGGGSPVDADDR----EAPPRLYLTRYVNATAGNPLVPAPSL 295 Query 321 PSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIV 380 P++PGR++KP IAVVT+ G IV+G GGPQ P G S GGDTI+AALRE AADD V+AIV Sbjct 296 PALPGRKNKPAIAVVTVAGAIVSGSGGPQLPPFGNRSVGGDTISAALREAAADDDVAAIV 355 Query 381 LRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTIT 440 LRVDS GGSVT SETIWR V +AR+ GKPVVASMGAVAASGGYY++ GAD IVANPGTIT Sbjct 356 LRVDSSGGSVTGSETIWRAVQQAREAGKPVVASMGAVAASGGYYIATGADTIVANPGTIT 415 Query 441 GSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDF 500 GSIGV+TGKLV R+LKDRLGVG+D VRT ANADAWSI+APFT +QQ E ADLFY+DF Sbjct 416 GSIGVVTGKLVARELKDRLGVGTDTVRTGANADAWSINAPFTAEQQGQVENVADLFYNDF 475 Query 501 VERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEV 560 V RVA+GR ++T+AVD VARGRVWTGADA +RGLVDELGGLRTAVRRAKVLAGLDED +V Sbjct 476 VRRVAQGRNLSTEAVDAVARGRVWTGADAAERGLVDELGGLRTAVRRAKVLAGLDEDAQV 535 Query 561 RIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGE 620 R VSYPGSSLWD VRPR SS+P AASLPDA+G LL RS+ GI++Q E++++GA VLWLGE Sbjct 536 RTVSYPGSSLWDFVRPRQSSQP-AASLPDAVGGLLMRSLAGILDQAERSVNGAHVLWLGE 594 Query 621 SR 622 SR Sbjct 595 SR 596 >gi|315445955|ref|YP_004078834.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. Spyr1] gi|315264258|gb|ADU01000.1| signal peptide peptidase SppA, 67K type [Mycobacterium sp. Spyr1] Length=595 Score = 795 bits (2054), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/602 (70%), Positives = 493/602 (82%), Gaps = 9/602 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M+A L +P +D+R ++DTARH GVP+GC+LE +L+S PPE+ GFDP+ +L+G GR Sbjct 1 MLALLSGVPGFDDVRHFARKLDTARHQGVPDGCILELDLQSAPPESAGFDPVALLSGAGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P+ LR+AV+A+HRAAEDPRVAGLIARVQ+ + GAVQELREAI AF+A KPSLAWAETY Sbjct 61 PLLLREAVSALHRAAEDPRVAGLIARVQIDAAAPGAVQELREAIVAFTAKKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVWMQPSG++GLVGFATNA FLRDAL K G+EAQF+A+GEYKSA NL Sbjct 121 PGTLSYYLASAFGEVWMQPSGTLGLVGFATNALFLRDALDKLGVEAQFIAKGEYKSAPNL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTED +T+ HREA T +++ L+ QVW AVA SR I V LD LADRAPLLRDDAVT GLI Sbjct 181 FTEDRYTEPHREADTALVNGLRTQVWDAVAASRGIDVATLDALADRAPLLRDDAVTAGLI 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPD--EKPPRMYLARYASSARPRLTPPVP 321 DR+GFRD+AYAR+A++ G + SPE+ PD + PPR+YL RYA + RP VP Sbjct 241 DRVGFRDEAYARIADMAGADGVSPETGSGGIDPDGDDAPPRLYLTRYARAKRPT----VP 296 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL 381 +P RR IAVVTL GPIV+GRGG Q P G S+AGGDTIAAALRE AADD V+AIV+ Sbjct 297 GLPNRRR---IAVVTLHGPIVSGRGGRQMSPRGGSNAGGDTIAAALREAAADDDVAAIVV 353 Query 382 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG 441 RVDSPGGSVTASETIWREV RAR+ G PVVASMG+VAASGGYYVSM ADAIVANP TITG Sbjct 354 RVDSPGGSVTASETIWREVVRARESGTPVVASMGSVAASGGYYVSMAADAIVANPATITG 413 Query 442 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV 501 SIGV+TGKLV RDLK+RLGVGSD+VRTNANADAWSI+APFT +Q A AEADLFY DFV Sbjct 414 SIGVVTGKLVARDLKERLGVGSDSVRTNANADAWSINAPFTEEQHAQVAAEADLFYDDFV 473 Query 502 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 561 RVAEGR ++ DAV+ VARGRVWTGADALDRGLVDELGGLRTAV RAK LAG+DEDT+V Sbjct 474 ARVAEGRGLSIDAVEQVARGRVWTGADALDRGLVDELGGLRTAVTRAKALAGIDEDTKVE 533 Query 562 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES 621 + PG+SL D++RP+PSS+PAAASLP+ +GAL +S+ G+V+Q +++LSG + LW G Sbjct 534 LQMLPGASLRDVLRPKPSSQPAAASLPELLGALAIQSVAGVVDQTQRSLSGVNALWTGNP 593 Query 622 RL 623 R Sbjct 594 RF 595 >gi|145225602|ref|YP_001136280.1| signal peptide peptidase SppA, 67K type [Mycobacterium gilvum PYR-GCK] gi|145218088|gb|ABP47492.1| signal peptide peptidase SppA, 67K type [Mycobacterium gilvum PYR-GCK] Length=595 Score = 794 bits (2050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/602 (70%), Positives = 493/602 (82%), Gaps = 9/602 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M+A L +P +D+R ++DTARH GVP+GC+LE +L+S PPE+ GFDP+ +L+G GR Sbjct 1 MLALLSGVPGFDDVRHFARKLDTARHQGVPDGCILELDLQSAPPESAGFDPVALLSGAGR 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P+ LR+AV+A+HRAAEDPRVAGLIARVQ+ + GAVQELREAI AF+A KPSLAWAETY Sbjct 61 PLLLREAVSALHRAAEDPRVAGLIARVQIDAAAPGAVQELREAIVAFTAKKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGEVWMQPSG++GLVGFATNA FLRDAL K G+EAQF+A+GEYKSA NL Sbjct 121 PGTLSYYLASAFGEVWMQPSGTLGLVGFATNALFLRDALDKLGVEAQFIAKGEYKSAPNL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FTED +T+ HREA T +++ L+ QVW AVA SR I V LD LADRAPLLRDDAVT GLI Sbjct 181 FTEDRYTEPHREADTALVNGLRTQVWDAVAASRGIDVATLDALADRAPLLRDDAVTAGLI 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPD--EKPPRMYLARYASSARPRLTPPVP 321 DR+GFRD+AYAR+A++ G + SPE+ PD + PPR+YL RYA + RP VP Sbjct 241 DRVGFRDEAYARIADMAGADGVSPETGSGGIDPDGDDAPPRLYLTRYARAKRPT----VP 296 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVL 381 +P RR IAVVT+ GPIV+GRGG Q P G S+AGGDTIAAALRE AADD V+AIV+ Sbjct 297 GLPNRRR---IAVVTVHGPIVSGRGGRQMSPRGGSNAGGDTIAAALREAAADDDVAAIVV 353 Query 382 RVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITG 441 RVDSPGGSVTASETIWREV RAR+ G PVVASMG+VAASGGYYVSM ADAIVANP TITG Sbjct 354 RVDSPGGSVTASETIWREVVRARESGTPVVASMGSVAASGGYYVSMAADAIVANPATITG 413 Query 442 SIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFV 501 SIGV+TGKLV RDLK+RLGVGSD+VRTNANADAWSI+APFT +Q A AEADLFY DFV Sbjct 414 SIGVVTGKLVARDLKERLGVGSDSVRTNANADAWSINAPFTEEQHAQVAAEADLFYDDFV 473 Query 502 ERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 561 RVAEGR ++ DAV+ VARGRVWTGADALDRGLVDELGGLRTAV RAK LAG+DEDT+V Sbjct 474 ARVAEGRGLSVDAVEKVARGRVWTGADALDRGLVDELGGLRTAVTRAKALAGIDEDTKVE 533 Query 562 IVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGES 621 + PG+SL D++RP+PSS+PAAASLP+ +GAL +S+ G+V+Q +++LSG + LW G Sbjct 534 LQMLPGASLRDVLRPKPSSQPAAASLPELLGALAIQSVAGVVDQTQRSLSGVNALWTGNP 593 Query 622 RL 623 R Sbjct 594 RF 595 >gi|120402354|ref|YP_952183.1| signal peptide peptidase SppA, 67K type [Mycobacterium vanbaalenii PYR-1] gi|119955172|gb|ABM12177.1| signal peptide peptidase SppA, 67K type [Mycobacterium vanbaalenii PYR-1] Length=594 Score = 790 bits (2041), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/604 (71%), Positives = 498/604 (83%), Gaps = 16/604 (2%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTG--- 80 M + L +P +D+R +VDTARH GVP+GC+LE +L+S PPE+ GFDP+ V++G Sbjct 1 MFSALSGVPGFDDVREFARKVDTARHQGVPDGCILELDLQSAPPESAGFDPIAVISGVIG 60 Query 81 GGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWA 140 GRP+ LR+AVAAIHRAAEDPRVAGLIARVQ+ +P G VQELR+AI AF+ KPSLAWA Sbjct 61 PGRPLLLREAVAAIHRAAEDPRVAGLIARVQIDAAPPGPVQELRDAIVAFTGKKPSLAWA 120 Query 141 ETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSA 200 ETYPGTLSYYLASAFGEVWMQPSG+VGLVGFAT+A FLRDAL K G++AQFV RGEYKSA Sbjct 121 ETYPGTLSYYLASAFGEVWMQPSGTVGLVGFATSALFLRDALDKLGVQAQFVTRGEYKSA 180 Query 201 ANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTC 260 ANLFT+D +TDAHREA T +++ L+ QVW AVA SR I ALD LADRAPLLRDDAVT Sbjct 181 ANLFTQDSYTDAHREADTALVNGLRTQVWDAVAASRGIDRAALDALADRAPLLRDDAVTA 240 Query 261 GLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPD--EKPPRMYLARYASSARPRLTP 318 GL+DRIGFRD+AYAR+AE+ G E SPE+ PD + PPR++LARYA + RP Sbjct 241 GLVDRIGFRDEAYARIAEMSGAEGVSPETG----DPDGEDAPPRLFLARYARTKRP---- 292 Query 319 PVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSA 378 S+PG R P IAVVT+ GPIV+GRGG Q P+G SS+G DTIAAALR AADD ++A Sbjct 293 ---SVPGLRRHPKIAVVTVAGPIVSGRGGRQMSPMGGSSSGADTIAAALRRAAADDDIAA 349 Query 379 IVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGT 438 IVLRVDSPGGSVT SETIWREV R R+RGKPVVASMGAVAASGGYYVSM ADAIVANPGT Sbjct 350 IVLRVDSPGGSVTGSETIWREVVRTRERGKPVVASMGAVAASGGYYVSMAADAIVANPGT 409 Query 439 ITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYS 498 ITGSIGV+TGKLV R+LKDRLGVGSD VRTNANADAWSI+APFT +QQAH EAEADLFY Sbjct 410 ITGSIGVLTGKLVARELKDRLGVGSDTVRTNANADAWSINAPFTDEQQAHVEAEADLFYR 469 Query 499 DFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDT 558 DFV+RVAEGR ++ +AV+ VARGRVWTGADAL+RGLVDELGGLRTA+RRAKVLAG+DEDT Sbjct 470 DFVQRVAEGRHLSVEAVEQVARGRVWTGADALERGLVDELGGLRTAIRRAKVLAGIDEDT 529 Query 559 EVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWL 618 V + + P SSL D++RP+PSS PAAASL + GAL +S++GI ++ +++L+G +VLWL Sbjct 530 RVEVENLPSSSLLDVLRPKPSSLPAAASLQEVFGALAIQSVLGIADRTQRSLTGVNVLWL 589 Query 619 GESR 622 GE+R Sbjct 590 GETR 593 >gi|169630869|ref|YP_001704518.1| protease IV SppA [Mycobacterium abscessus ATCC 19977] gi|169242836|emb|CAM63864.1| Possible protease IV SppA (endopeptidase IV) [Mycobacterium abscessus] Length=583 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/589 (62%), Positives = 452/589 (77%), Gaps = 15/589 (2%) Query 36 DLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPL-TVLTGGGRPMALRDAVAAI 94 D+ L+ +VDTARH GVP C+LE +L VPPE+ DPL VL+GG RP++LR +AAI Sbjct 9 DVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLSLRHTIAAI 68 Query 95 HRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETYPGTLSYYLASA 154 HRA EDPRVAGLIARVQ+PP+ AGAVQELR AI AFSAVKPSLAW+ETYP TL+YYLASA Sbjct 69 HRAIEDPRVAGLIARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPSTLAYYLASA 128 Query 155 FGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHR 214 FGEVWMQPSG+VGL+GFA TFLR AL KAG+EAQF+ RG+YKSAANLFTEDG+TDA R Sbjct 129 FGEVWMQPSGTVGLIGFAAKGTFLRGALDKAGVEAQFLTRGQYKSAANLFTEDGYTDAQR 188 Query 215 EAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYA 274 EA R+L+SL +QV +VA SR + +D LADRAPL R DAV GL+DRIG+RD+AYA Sbjct 189 EADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRIGYRDEAYA 248 Query 275 RMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAV 334 R+ EL+G++ D PP +YLARYA + +P++ P + S+PGR S+P I V Sbjct 249 RIGELIGLQD------------DRDPPLLYLARYARATKPQV-PSLSSLPGRPSRPAIGV 295 Query 335 VTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE 394 VTL GPIV+GR GP+ P GP+S GGD IA ALR+ ADDSV+AIVLRVDSPGGSV SE Sbjct 296 VTLAGPIVSGRSGPRLFPPGPAS-GGDVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSE 354 Query 395 TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRD 454 TIWREV RAR+ GKPVV SMG+VA SGGYYV+M ADAI+ANPGT+TGSIGV+TGK + + Sbjct 355 TIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVTGSIGVLTGKFITKG 414 Query 455 LKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDA 514 LK++LGVGSD++RTNANADAWS + PFT +Q+ EAE D+ Y DFV+RVA+GR +T DA Sbjct 415 LKEKLGVGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDA 474 Query 515 VDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMV 574 V VA+GR+W+G DAL+ GLVDELGG R AV +AK LA + D VRI ++P S L ++ Sbjct 475 VKAVAQGRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLL 534 Query 575 RPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 R R SS+PAAA++ DA+ +A+ V V++ ++TL A + LG+ R Sbjct 535 RQRSSSQPAAAAVTDAVLGRVAQLAVETVQRAQRTLGSAQAMMLGDYRF 583 >gi|289760851|ref|ZP_06520229.1| protease IV sppA [Mycobacterium tuberculosis GM 1503] gi|289708357|gb|EFD72373.1| protease IV sppA [Mycobacterium tuberculosis GM 1503] Length=364 Score = 659 bits (1699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/340 (100%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 284 KGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVN 343 KGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVN Sbjct 25 KGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVN 84 Query 344 GRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARA 403 GRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARA Sbjct 85 GRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARA 144 Query 404 RDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGS 463 RDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGS Sbjct 145 RDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGS 204 Query 464 DAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRV 523 DAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRV Sbjct 205 DAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRV 264 Query 524 WTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPA 583 WTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPA Sbjct 265 WTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPA 324 Query 584 AASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 AASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 325 AASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 364 Score = 50.4 bits (119), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/217 (27%), Positives = 89/217 (42%), Gaps = 14/217 (6%) Query 72 FDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQEL-REAIAAF 130 F PL + GG +A AA+ A D V+ ++ RV P A + + RE A Sbjct 91 FLPLGPSSAGGDTIA-----AALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 145 Query 131 SAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQ 190 KP +A + YY++ + P G +G T +RD + G+ + Sbjct 146 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 205 Query 191 FVARGEYKSAANL---FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELA 247 V A ++ FT D AHREA D + VA+ R + DA+D +A Sbjct 206 AVRTNANADAWSIDAPFTPD--QQAHREAEA---DLFYSDFVERVAEGRKMTTDAVDVVA 260 Query 248 DRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEK 284 DA+ GL+D +G A R L G+++ Sbjct 261 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDE 297 >gi|308231618|ref|ZP_07663896.1| peptidase, S49 (protease IV) family [Mycobacterium tuberculosis SUMu001] gi|308369980|ref|ZP_07666835.1| peptidase, S49 (protease IV) family [Mycobacterium tuberculosis SUMu002] gi|308216724|gb|EFO76123.1| peptidase, S49 (protease IV) family [Mycobacterium tuberculosis SUMu001] gi|308325734|gb|EFP14585.1| peptidase, S49 (protease IV) family [Mycobacterium tuberculosis SUMu002] Length=313 Score = 602 bits (1553), Expect = 4e-170, Method: Compositional matrix adjust. Identities = 301/312 (97%), Positives = 303/312 (98%), Gaps = 4/312 (1%) Query 22 VNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG 81 +NMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG Sbjct 1 MNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGG 60 Query 82 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE 141 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE Sbjct 61 GRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAE 120 Query 142 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 201 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA Sbjct 121 TYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 180 Query 202 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 261 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG Sbjct 181 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 240 Query 262 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP 321 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP Sbjct 241 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPSH 300 Query 322 SI----PGRRSK 329 P RRS+ Sbjct 301 RFLVAGPSRRSR 312 Score = 51.2 bits (121), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 58/217 (27%), Positives = 89/217 (42%), Gaps = 14/217 (6%) Query 350 FLPLGPSSAGGDTIA-----AALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 404 F PL + GG +A AA+ A D V+ ++ RV P A + + RE A Sbjct 51 FDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQEL-REAIAAF 109 Query 405 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 464 KP +A + YY++ + P G +G T +RD + G+ + Sbjct 110 SAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQ 169 Query 465 AVRTNANADAWSIDAPFTPD--QQAHREAEA---DLFYSDFVERVAEGRKMTTDAVDVVA 519 V A ++ FT D AHREA D + VA+ R + DA+D +A Sbjct 170 FVARGEYKSAANL---FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELA 226 Query 520 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDE 556 DA+ GL+D +G A R L G+++ Sbjct 227 DRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEK 263 >gi|308231619|ref|ZP_07663897.1| signal peptide peptidase SppA, 36K type [Mycobacterium tuberculosis SUMu001] gi|308369979|ref|ZP_07666834.1| signal peptide peptidase SppA, 36K type [Mycobacterium tuberculosis SUMu002] gi|308216725|gb|EFO76124.1| signal peptide peptidase SppA, 36K type [Mycobacterium tuberculosis SUMu001] gi|308325733|gb|EFP14584.1| signal peptide peptidase SppA, 36K type [Mycobacterium tuberculosis SUMu002] Length=289 Score = 559 bits (1440), Expect = 7e-157, Method: Compositional matrix adjust. Identities = 288/289 (99%), Positives = 289/289 (100%), Gaps = 0/289 (0%) Query 335 VTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE 394 +TLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE Sbjct 1 MTLEGPIVNGRGGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASE 60 Query 395 TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRD 454 TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRD Sbjct 61 TIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRD 120 Query 455 LKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDA 514 LKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDA Sbjct 121 LKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDA 180 Query 515 VDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMV 574 VDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMV Sbjct 181 VDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMV 240 Query 575 RPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 623 RPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL Sbjct 241 RPRPSSRPAAASLPDAMGALLARSIVGIVEQVEQTLSGASVLWLGESRL 289 Score = 50.1 bits (118), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/217 (27%), Positives = 89/217 (42%), Gaps = 14/217 (6%) Query 72 FDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQEL-REAIAAF 130 F PL + GG +A AA+ A D V+ ++ RV P A + + RE A Sbjct 16 FLPLGPSSAGGDTIA-----AALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 70 Query 131 SAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQ 190 KP +A + YY++ + P G +G T +RD + G+ + Sbjct 71 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 130 Query 191 FVARGEYKSAANL---FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELA 247 V A ++ FT D AHREA D + VA+ R + DA+D +A Sbjct 131 AVRTNANADAWSIDAPFTPD--QQAHREAEA---DLFYSDFVERVAEGRKMTTDAVDVVA 185 Query 248 DRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEK 284 DA+ GL+D +G A R L G+++ Sbjct 186 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDE 222 >gi|336460641|gb|EGO39532.1| ClpP class periplasmic serine protease [Mycobacterium avium subsp. paratuberculosis S397] Length=376 Score = 493 bits (1270), Expect = 3e-137, Method: Compositional matrix adjust. Identities = 243/331 (74%), Positives = 280/331 (85%), Gaps = 13/331 (3%) Query 24 MVAFLPSIPVV----EDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLT 79 M A L SIP + +++RAL GRVDTARHHGVPNGCVLE +LRS+PPET+GFDPL ++T Sbjct 1 MFAVLSSIPGLSKGADEIRALAGRVDTARHHGVPNGCVLELDLRSMPPETSGFDPLALVT 60 Query 80 GGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAW 139 GG RP +LRD V AIHRAAEDPRVAGLIARVQL PSP+ AVQELREAI AF+A KPSLAW Sbjct 61 GGSRPASLRDTVDAIHRAAEDPRVAGLIARVQLAPSPSAAVQELREAIVAFTAAKPSLAW 120 Query 140 AETYPGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKS 199 AETYPGTLSYYLASAFGE+WMQP GSVGL+GFA+NATFLRDAL KAGIEAQFVARGEYKS Sbjct 121 AETYPGTLSYYLASAFGEIWMQPGGSVGLIGFASNATFLRDALDKAGIEAQFVARGEYKS 180 Query 200 AANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVT 259 A N FTE GFT+AHREAVTRMLDS+Q+QVWQAVA+SR + DALD LADRAPLLR DA+ Sbjct 181 AVNRFTEHGFTEAHREAVTRMLDSVQEQVWQAVAESRKLDTDALDALADRAPLLRQDALD 240 Query 260 CGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPP 319 GL+DRIGFRDQAY R+AELVGV+ SPD +PPR+Y++RYA +AR RL+PP Sbjct 241 SGLVDRIGFRDQAYDRIAELVGVQ---------DVSPDTEPPRLYVSRYAGAARSRLSPP 291 Query 320 VPSIPGRRSKPTIAVVTLEGPIVNGRGGPQF 350 VPS+PGRR PT+AV+ ++G +V+GRGGP F Sbjct 292 VPSLPGRRRPPTVAVINVDGTLVDGRGGPPF 322 Score = 61.6 bits (148), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 69/226 (31%), Positives = 98/226 (44%), Gaps = 17/226 (7%) Query 366 ALREVAADDSVSAIVLRVD-SPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYY 424 A+ A D V+ ++ RV +P S E RE A KP +A + YY Sbjct 74 AIHRAAEDPRVAGLIARVQLAPSPSAAVQE--LREAIVAFTAAKPSLAWAETYPGTLSYY 131 Query 425 VSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPD 484 ++ I PG G IG + +RD D+ G+ + V A + S FT Sbjct 132 LASAFGEIWMQPGGSVGLIGFASNATFLRDALDKAGIEAQFV---ARGEYKSAVNRFTEH 188 Query 485 --QQAHREAEADLFYS---DFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELG 539 +AHREA + S + VAE RK+ TDA+D +A DALD GLVD +G Sbjct 189 GFTEAHREAVTRMLDSVQEQVWQAVAESRKLDTDALDALADRAPLLRQDALDSGLVDRIG 248 Query 540 GLRTAVRRAKVLAGLDE---DTE---VRIVSYPGSSLWDMVRPRPS 579 A R L G+ + DTE + + Y G++ + P PS Sbjct 249 FRDQAYDRIAELVGVQDVSPDTEPPRLYVSRYAGAARSRLSPPVPS 294 >gi|333991950|ref|YP_004524564.1| signal peptide peptidase SppA 67K type [Mycobacterium sp. JDM601] gi|333487918|gb|AEF37310.1| signal peptide peptidase SppA 67K type [Mycobacterium sp. JDM601] Length=280 Score = 388 bits (996), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 194/281 (70%), Positives = 227/281 (81%), Gaps = 3/281 (1%) Query 24 MVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGR 83 M + LP +P ++DLR + R+DTARHHGVP+G VLE +L+S+P ET GFDPL ++ G + Sbjct 1 MFSLLPGVPGLDDLRGVARRIDTARHHGVPDGVVLELDLQSLPHETGGFDPLALIRSGSQ 60 Query 84 PMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAVKPSLAWAETY 143 P LRD VAAIHRAAEDPRVAGLIARVQL + AG VQELR AIA F+AVKPSLAWAETY Sbjct 61 PPVLRDVVAAIHRAAEDPRVAGLIARVQLSSAAAGPVQELRAAIADFTAVKPSLAWAETY 120 Query 144 PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL 203 PGTLSYYLASAFGE+WMQPSG+VGL+GFATNATFLR AL KAGIEAQF+ARGEYKSAANL Sbjct 121 PGTLSYYLASAFGEIWMQPSGTVGLIGFATNATFLRTALDKAGIEAQFIARGEYKSAANL 180 Query 204 FTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLI 263 FT+D +TDAHREA T +++SL QV QAVA+SRN+ +DELADRAPLLRDDAV GL+ Sbjct 181 FTQDSYTDAHREADTALVESLHAQVRQAVAESRNLDAAVVDELADRAPLLRDDAVQAGLV 240 Query 264 DRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMY 304 DRIGFRD+AY R+AEL G G +S+ PD P +Y Sbjct 241 DRIGFRDEAYGRIAELAG---GPGDSAADPDGPDAPPRLLY 278 Score = 44.3 bits (103), Expect = 0.069, Method: Compositional matrix adjust. Identities = 51/196 (27%), Positives = 79/196 (41%), Gaps = 9/196 (4%) Query 363 IAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGG 422 + AA+ A D V+ ++ RV + + + +A KP +A + Sbjct 67 VVAAIHRAAEDPRVAGLIARVQLSSAAAGPVQELRAAIADFT-AVKPSLAWAETYPGTLS 125 Query 423 YYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFT 482 YY++ I P G IG T +R D+ G+ + + A ++ FT Sbjct 126 YYLASAFGEIWMQPSGTVGLIGFATNATFLRTALDKAGIEAQFIARGEYKSAANL---FT 182 Query 483 PDQ--QAHREAEADL---FYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDE 537 D AHREA+ L ++ + VAE R + VD +A DA+ GLVD Sbjct 183 QDSYTDAHREADTALVESLHAQVRQAVAESRNLDAAVVDELADRAPLLRDDAVQAGLVDR 242 Query 538 LGGLRTAVRRAKVLAG 553 +G A R LAG Sbjct 243 IGFRDEAYGRIAELAG 258 >gi|284032927|ref|YP_003382858.1| signal peptide peptidase SppA, 36K type [Kribbella flavida DSM 17836] gi|283812220|gb|ADB34059.1| signal peptide peptidase SppA, 36K type [Kribbella flavida DSM 17836] Length=552 Score = 372 bits (955), Expect = 1e-100, Method: Compositional matrix adjust. Identities = 231/541 (43%), Positives = 311/541 (58%), Gaps = 32/541 (5%) Query 54 NGCVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLP 113 G VLE +L ET PL + P +R+ V + +AAED +V GL+A V P Sbjct 2 TGIVLELDLTRGVLETPPGSPLAAVRARHLP-TVRELVVGLRKAAEDEQVVGLVAHVGGP 60 Query 114 PSPAGAVQELREAIAAFSAV-KPSLAWAETYP----GTLSYYLASAFGEVWMQPSGSVGL 168 VQELR A+ F A K ++AW+E++ GT+ YYLA+AF E+W+QPSG +G+ Sbjct 61 ALSLAQVQELRTAVVGFRAAGKRAVAWSESFGEAGGGTVPYYLATAFDEIWVQPSGELGI 120 Query 169 VGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQV 228 G + ATF+R AL KAG+ QF R EYK+A + FTE T RE R+ +S +Q+ Sbjct 121 TGVSVQATFVRGALDKAGVIPQFGKRREYKTAVDTFTEKEMTGPAREMAARLAESAYEQL 180 Query 229 WQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPE 288 + +A R + V+ + EL D APL + GL+DR+G+R Y + + G P Sbjct 181 VEGIAGERELSVERVRELVDNAPLAAEAGREAGLVDRLGYRSDVYDELEKRFG-----PT 235 Query 289 SSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR--- 345 ++ + + RY L + ++P KPT+AV+ + G I GR Sbjct 236 TA------------LLVERYHRRGPRTLHDALDNLPWP-PKPTVAVIRVNGGITVGRSSG 282 Query 346 GGPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARD 405 GGP LG +G DTI AALR VAADD V A+VLR+DSPGGS AS+ I EV R R Sbjct 283 GGP----LGSPRSGSDTITAALRAVAADDKVKAVVLRIDSPGGSYVASDAIRHEVLRLRS 338 Query 406 RGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDA 465 GKPV+ASMG+VAASGGY+V+M AD +VA PGTITGSIGV++GK VVRD R+G+ A Sbjct 339 TGKPVIASMGSVAASGGYFVAMPADVVVAQPGTITGSIGVLSGKGVVRDALGRIGITQQA 398 Query 466 VRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWT 525 V NA +S F+P Q E D Y+DFV + AE R + D ++ +ARGRVWT Sbjct 399 VSEGTNARMYSAQEEFSPQQWERLEETLDRIYADFVAKAAEDRGLGVDELEALARGRVWT 458 Query 526 GADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAA 585 GADA LVDELGG A++ A AGLD D + + + P + D +RP S+ AA Sbjct 459 GADAHRHQLVDELGGFEHALQLACARAGLDRD-HIAVTAAPHRTFLDRLRPPTSTDDLAA 517 Query 586 S 586 + Sbjct 518 T 518 >gi|271969371|ref|YP_003343567.1| signal peptide peptidase SppA, 67K type [Streptosporangium roseum DSM 43021] gi|270512546|gb|ACZ90824.1| signal peptide peptidase SppA, 67K type [Streptosporangium roseum DSM 43021] Length=566 Score = 364 bits (935), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 231/531 (44%), Positives = 306/531 (58%), Gaps = 34/531 (6%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 VLE +L + DPL+ L R +L D ++ + RA +D RV LI ++ P Sbjct 22 LVLELDLTDGLSDGPPSDPLSALLAM-RKTSLTDVLSGLKRARKDSRVKALIVKIGTQPL 80 Query 116 PAGAVQELREAIAAFSAV-KPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVG 170 VQ+LR+A+ F A K ++A+AET+ GT+ YYL SAF V++QPSG VGL G Sbjct 81 GLAMVQDLRQAVIEFRAAGKLTVAFAETFGEFGAGTVPYYLGSAFERVYLQPSGDVGLTG 140 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 A FLR AL K G+E Q R EYK+AAN FT+D TD HRE++ R+ +S+ +Q+ Sbjct 141 VAMEQRFLRGALGKLGVEYQMGQRHEYKTAANTFTQDHMTDPHRESMGRITESVTEQIVA 200 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 VA+ R + + +L D P + +AV GL+DR+ +RD+ Y + + VG Sbjct 201 GVAEGRGLEPTKVRKLIDEGPFIGAEAVEAGLVDRMAYRDEVYDEVKQAVG--------- 251 Query 291 GSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQF 350 + +Y+ RYA P +P R + T+A+V G I GR G Sbjct 252 -------DDALLLYVGRYAKG------PIAKKLP-RPGEETVALVHGNGAIRLGRSGRS- 296 Query 351 LPLGPSSA-GGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKP 409 PLG SA G DT+ AALR D+ V A+V RVDSPGGS AS+ IWREV R GKP Sbjct 297 -PLGGGSAMGSDTVCAALRAARRDEHVKAVVFRVDSPGGSYVASDAIWREVVLTRKAGKP 355 Query 410 VVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTN 469 +V SMG +AASGGY VSM ADAIVA PGT+TGSIGV GK V+ L +++GV S+ V Sbjct 356 IVVSMGDLAASGGYMVSMAADAIVAQPGTLTGSIGVFGGKAVIGGLLEKIGVSSETVGEG 415 Query 470 ANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADA 529 ANA +S F+ Q A A D Y DFV +VAEGR ++ + +A+GRVWTGADA Sbjct 416 ANAGMFSSTNAFSEAQWARVNAWLDRVYEDFVNKVAEGRGLSRERAHELAKGRVWTGADA 475 Query 530 LDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSS 580 GLVDELGGL+ A+ A+ AGL D VR +YP S + +RP SS Sbjct 476 HAHGLVDELGGLQDALALARRKAGLAADAPVR--AYPRLSPLERLRPADSS 524 >gi|269127810|ref|YP_003301180.1| signal peptide peptidase SppA, 67K type [Thermomonospora curvata DSM 43183] gi|268312768|gb|ACY99142.1| signal peptide peptidase SppA, 67K type [Thermomonospora curvata DSM 43183] Length=570 Score = 362 bits (930), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 245/549 (45%), Positives = 323/549 (59%), Gaps = 34/549 (6%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 VLE +L E DPL+ L R LRD + + +A D RV LI RV Sbjct 22 LVLELDLADGIVEAAPADPLSALLSM-RRTHLRDVLDGLRKARGDARVRALIVRVGGTIG 80 Query 116 PAGAVQELREAIAAF-SAVKPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVG 170 A A QELR+A+ A A K ++AW+ET+ G + YYLASAF V++QP+G VGL G Sbjct 81 LAMA-QELRDAVTALRQAGKLTVAWSETFGEGRQGNVPYYLASAFDRVYLQPTGEVGLTG 139 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 A FLR AL KAGIE +F AR EYK+ AN+F E +T HRE+ R++DS Q+ + Sbjct 140 VALEEPFLRGALEKAGIEPRFAARHEYKTVANMFMERAYTPEHRESSQRLVDSAGRQLAE 199 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 +A+ R + V+ + EL DR PLL +A+ GL+DR+ +RD+ YA + E VG Sbjct 200 GIAQGRGLTVERVRELIDRGPLLAAEALEAGLVDRLAYRDEVYAEVREKVG--------- 250 Query 291 GSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIV---NGRGG 347 PD + Y++RY + L +P PGR+ +A++ GPI +GRGG Sbjct 251 ----GPDGRVQLRYVSRYNRTHG--LAEHLPQ-PGRQD--AVALINGLGPIRLGRSGRGG 301 Query 348 PQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRG 407 P LP + G DTI AA R D+ + AIV RV+SPGGS AS+ IWREV AR G Sbjct 302 P--LPSQGPAMGSDTIGAAFRAAVRDERIKAIVFRVNSPGGSAVASDAIWREVVLARRAG 359 Query 408 KPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVR 467 KPV+ SMG VAASGGYYV+M AD IVA PGTITGSIGV+TGK V+ L +R+GVG +V Sbjct 360 KPVIVSMGDVAASGGYYVAMAADVIVAQPGTITGSIGVVTGKAVLSGLLERIGVGMGSVT 419 Query 468 TNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGA 527 +A +S F+P + A D Y +F +VAEGR ++ V+ +ARGRVWTGA Sbjct 420 DGEHALMYSAIKDFSPSEWERINASLDHIYENFTAKVAEGRGLSRRRVEELARGRVWTGA 479 Query 528 DALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSS--RPAAA 585 DA + GLVDELGGL A+ A+ AGL D VR ++P + +RP SS R AA+ Sbjct 480 DAKEHGLVDELGGLELALELARKKAGLPADAPVR--TFPHLGPLERLRPAESSEDRAAAS 537 Query 586 SLPDAMGAL 594 + D G+L Sbjct 538 ARFDGWGSL 546 >gi|296270823|ref|YP_003653455.1| signal peptide peptidase SppA, 36K type [Thermobispora bispora DSM 43833] gi|296093610|gb|ADG89562.1| signal peptide peptidase SppA, 36K type [Thermobispora bispora DSM 43833] Length=563 Score = 362 bits (929), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 231/538 (43%), Positives = 307/538 (58%), Gaps = 37/538 (6%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 VLE +L E DPL + R + L D +A ++RA DPRV L+ ++ P Sbjct 22 LVLELDLTMGIVEGPPADPLGAMLSM-RKIRLDDVLAGLNRARRDPRVKALLVKIGNAPL 80 Query 116 PAGAVQELREAIAAFSAV-KPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVG 170 G VQELR AI A K ++A+AE++ GT+ YYLA+A +++QPSG VGL G Sbjct 81 GLGMVQELRTAIIKLRAAGKRTIAFAESFGEVSTGTVPYYLATACDRIYLQPSGDVGLTG 140 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 + FLRDAL KAG+E Q R EYK+AAN+FT++ T+ HRE+ R+++S +QV + Sbjct 141 LSVETRFLRDALAKAGVEFQLGQRHEYKTAANVFTQNHMTEPHRESTARIVESAMEQVIE 200 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 +A+ R + + EL DR P L +AV GL+D + +RD+ YA E VG Sbjct 201 GIAQGRRLDPARVRELVDRGPFLGAEAVEAGLVDGLKYRDEVYA---ETVG--------- 248 Query 291 GSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQF 350 E Y+ RYA A + P PG +A++ GPI GR G Sbjct 249 -------EDGRLRYVTRYAKEAAAKRLPH----PG---AGAVALIHGIGPIRLGRSGRS- 293 Query 351 LPLGPS-SAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKP 409 PLG S S G DTI AA R DD + A+V RVDSPGGS AS+ IWREV R GKP Sbjct 294 -PLGASGSMGSDTICAAFRAARKDDKIKAVVFRVDSPGGSYVASDAIWREVLLTRQAGKP 352 Query 410 VVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTN 469 V+ SMG VAASGGY+VSM A+ I A+PGT+TGSIGV GK V+ +L +LGV S+AV Sbjct 353 VIVSMGDVAASGGYFVSMAANVIFAHPGTLTGSIGVYGGKPVISELLGKLGVTSEAVSMG 412 Query 470 ANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADA 529 NA+ +S F+ Q D Y DFV +VA+ R ++ D +A+GRVWTGADA Sbjct 413 ENAEMFSTSREFSAAQWERLNTWLDRVYEDFVTKVADARGLSKDHAHELAKGRVWTGADA 472 Query 530 LDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASL 587 + GLVDELGGL A+ A+ AGL VRI YP + + +RP SS +A++ Sbjct 473 VRNGLVDELGGLEDALALARSRAGLPATAPVRI--YPHLNPLERIRPPESSEDRSAAM 528 >gi|72160983|ref|YP_288640.1| signal peptide peptidase A [Thermobifida fusca YX] gi|71914715|gb|AAZ54617.1| signal peptide peptidase A. Serine peptidase. MEROPS family S49 [Thermobifida fusca YX] Length=569 Score = 361 bits (927), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 218/513 (43%), Positives = 300/513 (59%), Gaps = 29/513 (5%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 VLE +L + DPL+ + R L D V I R A DPRV LI ++ Sbjct 21 LVLELDLTEGMIDEPPGDPLSQIMAM-RRQRLFDIVEGIRRGAHDPRVKALIVKIGSQSL 79 Query 116 PAGAVQELREAIAAFS-AVKPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVG 170 VQELR+A+A F A K ++AW+E++ PG+L YYLA+AF E+ + PSGSVGL G Sbjct 80 GMALVQELRQAVAMFRRAGKHTVAWSESFGEFGPGSLPYYLATAFDEIALLPSGSVGLTG 139 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 F +AL K G++ Q AR EYK+A N+FTE GFTDAHREA R+++SL +Q+ Sbjct 140 LRVENLFFAEALEKLGVDYQGGARHEYKTALNMFTERGFTDAHREASGRIVESLTEQLVA 199 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 ++ R++ + + EL D+ P L +AV GL+D++ +RD+ Y+ + + Sbjct 200 GISSGRDLSEERVRELIDQGPFLATEAVEAGLVDKVAYRDEIYSDLLD------------ 247 Query 291 GSQTSPDEKPPRM-YLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQ 349 + S D P + Y++RY R +P + +A+++ G IV GR + Sbjct 248 --RYSADGTPAHLQYVSRYQ-----RTRSLADRVPVAQRSGYVALISGVGQIVTGRS--R 298 Query 350 FLPLGPSSA-GGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGK 408 PLG + G DT+AAA R D +V A+V RV+SPGGS TAS+ IWREV G Sbjct 299 RSPLGGGAVMGSDTVAAAFRAARKDPNVRAVVFRVNSPGGSYTASDVIWREVVLTSQAGT 358 Query 409 PVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRT 468 PVV SMG VA SGGY+++ GAD I+A PGTITGSIGV+ GK V+ + +LGV SD + + Sbjct 359 PVVVSMGDVAGSGGYFIAAGADVIIAQPGTITGSIGVVVGKAVLSTMLAKLGVTSDWIDS 418 Query 469 NANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGAD 528 +A +S + PF+ + D Y DFV +VAEGRKMT D V VA+GR+WTG D Sbjct 419 GNHAGMFSPNRPFSESEWERVNTMLDHIYDDFVGKVAEGRKMTRDQVHEVAKGRIWTGQD 478 Query 529 ALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVR 561 A +RGLVDE+GGL TA+R A+ GL VR Sbjct 479 ACERGLVDEVGGLETAIRIARDRGGLPPSAPVR 511 >gi|23015704|ref|ZP_00055473.1| COG0616: Periplasmic serine proteases (ClpP class) [Magnetospirillum magnetotacticum MS-1] Length=560 Score = 357 bits (915), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 228/558 (41%), Positives = 312/558 (56%), Gaps = 45/558 (8%) Query 52 VPNGCVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQ 111 VP VL +L + +T +PL L+G R LR V A+ RAA D RV GL A + Sbjct 41 VPERVVLTLDLDAPFRDTGEANPLAQLSGE-RSYGLRQTVEALDRAALDSRVTGLFATMG 99 Query 112 LPPSPAGAVQELREAIAAFSAV-KPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSV 166 Q+LR+A+ F A K ++ +AET GTL YYLA+AF +VW+QPSG V Sbjct 100 HSSLGLAGRQDLRDAVIRFRASGKSAVLFAETMGEGGSGTLDYYLAAAFSQVWLQPSGDV 159 Query 167 GLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQD 226 GL G + F++ L G++AQF R EYKSA ++FTE GFT AHRE + R+LDS + Sbjct 160 GLTGLWVESPFIKGTLDLLGMKAQFSGRHEYKSAIDMFTETGFTPAHRENLGRLLDSWSE 219 Query 227 QVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGS 286 Q+ +A +R + D + +L + P L +A+ L+D++G+RDQA+ +A + Sbjct 220 QIISGIAANRGLPEDRVRDLMGKGPFLASEALNAKLVDKVGYRDQAWEIVAGI------- 272 Query 287 PESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRG 346 G+ + D M LA YA + R IA+++ G I RG Sbjct 273 ----GTDKAED-----MDLADYAGH-----------LDKARGGAKIALISGIGAI--HRG 310 Query 347 GPQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDR 406 + G G T+A A R+ DD V AI+ RVDSPGGS TAS+T+ EVARAR Sbjct 311 ESRHGLDGDGDFGAQTVAEAFRDAVDDDKVKAILFRVDSPGGSYTASDTVHHEVARARAA 370 Query 407 GKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAV 466 GKPVV SMG AASGGY+V+MGAD I+A PGTITGSIGV TGK+V+ D +LG+ D + Sbjct 371 GKPVVVSMGNYAASGGYFVAMGADRIIAAPGTITGSIGVFTGKVVLEDFWKKLGISWDQM 430 Query 467 RTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTG 526 + NA WS + PFTP +A +A D Y+DF + ++ R + +D +ARGRVWTG Sbjct 431 QRGDNAGIWSANQPFTPQAKARIDALLDHIYADFTGKASQARNLDAARMDKLARGRVWTG 490 Query 527 ADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAAS 586 ADA + GLVD LGG A+ + + +AGL D + +V +P RPR A S Sbjct 491 ADAKESGLVDGLGGWTEALAQLRQVAGLKADEPLSLVEFP--------RPRKPWEVLAES 542 Query 587 LPDAMGALLARSIVGIVE 604 L G + R I+ +E Sbjct 543 L--GGGGVAERRILSRIE 558 >gi|108762546|ref|YP_635601.1| signal peptide peptidase SppA, 67K type [Myxococcus xanthus DK 1622] gi|108466426|gb|ABF91611.1| signal peptide peptidase SppA, 67K type [Myxococcus xanthus DK 1622] Length=680 Score = 350 bits (899), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 226/580 (39%), Positives = 326/580 (57%), Gaps = 51/580 (8%) Query 21 WVNMVAFLPSIPVVEDLRALVGR--VDTARHHGVPNGCVLEFNLRSVPPETTGFDPLTVL 78 ++ +AF+ ++ V+ + LVG + +A GVP+ VLE +L E G + L + Sbjct 89 FIGALAFVGALSVL-FVVGLVGLMLLASASKPGVPSNLVLELDLEDPLSEHGGGESL-MG 146 Query 79 TGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAV-KPSL 137 G P +RD V A+ +A +D RV L+ R+ P +PA A QELR+A+ AF A K ++ Sbjct 147 AFGEEPTTVRDVVEALEKAGDDARVKSLLVRIGHPGTPA-ATQELRDAVKAFRAKGKKAV 205 Query 138 AWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVA 193 A+++++ TL YYLASAF E+++QPSG V + G A F R+A + G+ ++ A Sbjct 206 AYSDSFGELGNSTLGYYLASAFDEIYIQPSGDVNINGLAFELPFAREAFTRLGVTPRYFA 265 Query 194 RGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLL 253 R EYK+A N +TE FT HREA +SL Q+ + +A+ R + D + L D+APL+ Sbjct 266 RYEYKNAINSYTEQDFTAPHREATEGFTNSLFGQIVRGIAEDRGLTEDVVRGLIDKAPLM 325 Query 254 RDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSAR 313 +A+ L+ + +RD+ + E G E +Y+ +Y A Sbjct 326 AQEAMEAKLVTGLRYRDEVLGGLKEQAG----------------EGARFLYVKKYLERAG 369 Query 314 PRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPL-GPSSAGGDTIAAALREVAA 372 P++ G TIA+V G ++ RG Q PL G S G +++AAALR+ Sbjct 370 K------PNVSGN----TIALVYGVGEVM--RGKNQSNPLSGGQSMGAESVAAALRKATE 417 Query 373 DDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAI 432 D V AIV RVDSPGGS AS+T+ REV RA++ GKPV+ +MG+ AASGGY+V+M AD I Sbjct 418 DSRVKAIVFRVDSPGGSYVASDTVRREVQRAKEAGKPVIVTMGSYAASGGYFVAMEADRI 477 Query 433 VANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAE 492 VA+PGT+TGSIGV GK V ++LGV D+V NA+ + DA +TP+QQA +A Sbjct 478 VAHPGTLTGSIGVYAGKFVTAGFWEKLGVNFDSVAAGKNAEMFGSDADYTPEQQARMDAS 537 Query 493 ADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLA 552 D Y+DF R A RK+ + + +A+GRVWTG DAL GLVD LGG A+ AK A Sbjct 538 LDRIYADFTTRAAASRKLPLEKLQSLAKGRVWTGEDALAHGLVDALGGYPKALELAKEAA 597 Query 553 GLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMG 592 L D V + Y P +PA+A L + +G Sbjct 598 KLPADARVNVEVY------------PRKKPASALLSELLG 625 >gi|258652617|ref|YP_003201773.1| signal peptide peptidase SppA, 36K type [Nakamurella multipartita DSM 44233] gi|258555842|gb|ACV78784.1| signal peptide peptidase SppA, 36K type [Nakamurella multipartita DSM 44233] Length=561 Score = 347 bits (891), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 240/538 (45%), Positives = 318/538 (60%), Gaps = 33/538 (6%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 +LE +L + P E +PL L GR LR + A+H AA+DPRV GL+ARV P Sbjct 12 ILLELDLSTAPVELDPAEPLARLRQRGR-RDLRATLRALHEAADDPRVVGLVARVG-GPL 69 Query 116 PAGAVQELREAIAAFSAV-KPSLAWAETY---PGTLS-YYLASAFGEVWMQPSGSVGLVG 170 P +QELR + AF+A KP+LAWA+T+ PG ++ Y LA+AF E+W+QP G VGL+G Sbjct 70 PWSVMQELRAGVRAFAAGGKPTLAWAQTFAEQPGAMAGYVLATAFDELWLQPGGEVGLLG 129 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 A TFLR +L K G++ Q R EYK+AA+ +T AHREA+ R++ S+ D + Sbjct 130 VALETTFLRGSLDKLGLQPQLDQRHEYKNAADTIMRTEYTRAHREALDRVVGSVFDDAVE 189 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 A+A+ R + + L D P L A GL+DR+G+RD+A A M VG E Sbjct 190 AIAQGRRLDPAQVRTLVDGGPTLAPAARDAGLVDRLGYRDEALAAMRVRVGDE------- 242 Query 291 GSQTSPDEKPPRMYLA--RYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGP 348 P + A R+ PGRR +A+VT++G I +GR Sbjct 243 ----------PELLFADRWRPRRRPLRIVGGTLGRPGRRGH--VALVTIQGTIDSGRSRR 290 Query 349 QFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGK 408 + +AG DT+ AALR AAD+ A+VLRVDSPGGS ASETIWREV + R K Sbjct 291 GLMG---RTAGSDTVGAALRAAAADERARAVVLRVDSPGGSAVASETIWREVCLLQ-RAK 346 Query 409 PVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRT 468 PV+ +MGAVAASGGYYV+ AD IVA P T+TGSIGV GK+VV++L RLG+ + +V+ Sbjct 347 PVIVAMGAVAASGGYYVACPADRIVALPATLTGSIGVFGGKVVVQELMTRLGLSAGSVQR 406 Query 469 NANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGAD 528 A+A +S PF D++ + A D Y DFV +VA+GR +T ++ VARGRVWTG D Sbjct 407 GAHARMFSSRRPFDEDEKTNLAAGLDAIYDDFVGKVAQGRGRSTGQIEAVARGRVWTGRD 466 Query 529 ALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAAS 586 A+ GLVDELGGLR AVR A+ GL D VR G L RPR S+ P A++ Sbjct 467 AVAAGLVDELGGLRDAVRLARARGGLAPDAPVRPAIRLG-PLARFGRPRNSADPRAST 523 >gi|338531431|ref|YP_004664765.1| signal peptide peptidase SppA, 67K type [Myxococcus fulvus HW-1] gi|337257527|gb|AEI63687.1| signal peptide peptidase SppA, 67K type [Myxococcus fulvus HW-1] Length=597 Score = 345 bits (886), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 225/553 (41%), Positives = 310/553 (57%), Gaps = 47/553 (8%) Query 46 TARHHGVPNGCVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAG 105 +A GVP+ VLE +L + PE D L + G P +RD V A+ +A ED RV Sbjct 31 SASKPGVPSNLVLELDLENPLPEHGAGDSL-MGAFGEEPTTVRDVVEALEKAGEDARVKA 89 Query 106 LIARVQLPPSPAGAVQELREAIAAFSAV-KPSLAWAETY----PGTLSYYLASAFGEVWM 160 L+ R+ P +PA A QELR+A+ AF A K ++A+++T+ TL+YYLASAF E+++ Sbjct 90 LLVRIGHPGTPA-AAQELRDAVKAFRAKGKKAVAYSDTFGELGNSTLAYYLASAFDEIYL 148 Query 161 QPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRM 220 QPSG V + G A F R A K G+ ++ AR EYK+A N +TE +T HREA R Sbjct 149 QPSGDVNINGLAFELPFARAAFDKLGVTPRYFARHEYKNAVNSYTEQDYTAPHREATERF 208 Query 221 LDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELV 280 +SL Q+ + +A+ R + +A+ L D+APL+ +A+ L+ + +RD E++ Sbjct 209 TNSLFGQIVKGIAEDRGLTEEAVRGLVDKAPLMASEALEAKLVTGLRYRD-------EVL 261 Query 281 GVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGP 340 G G + E +Y+ +Y A P TIA+V G Sbjct 262 G---------GLEAQAGEGARFLYVKKYLERA---------GRPYAAGGDTIALVYGVGE 303 Query 341 IVNGRGGPQFLPL-GPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWRE 399 ++ RG Q PL G G +++AAALR+ D V AIV RVDSPGGS AS+T+ RE Sbjct 304 VM--RGKSQSNPLSGGQGMGAESVAAALRKATEDARVKAIVFRVDSPGGSYVASDTVRRE 361 Query 400 VARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRL 459 V RAR+ GKPV+ +MG+ AASGGY+ +M AD IVA PGT+TGSIGV GK V ++L Sbjct 362 VQRAREAGKPVIVTMGSYAASGGYFAAMEADRIVAQPGTLTGSIGVYAGKFVTAAFWEKL 421 Query 460 GVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVA 519 GV D+V NA+ + DA +TP+Q A EA D Y+DF RVA RK+ + V +A Sbjct 422 GVNFDSVSAGKNAEMFGSDADYTPEQAARMEATLDRIYADFTTRVAATRKLPLEQVQALA 481 Query 520 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPS 579 +GRVWTG DAL GLVD LGG A+ AK A L D V + Y P Sbjct 482 KGRVWTGEDALANGLVDALGGYSKALALAKEAAKLPADARVNVEVY------------PR 529 Query 580 SRPAAASLPDAMG 592 +PA+A L + +G Sbjct 530 KKPASAVLSELLG 542 >gi|310825614|ref|YP_003957972.1| Signal peptide peptidase SppA, 67K type [Stigmatella aurantiaca DW4/3-1] gi|309398686|gb|ADO76145.1| Signal peptide peptidase SppA, 67K type [Stigmatella aurantiaca DW4/3-1] Length=598 Score = 345 bits (886), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 205/486 (43%), Positives = 287/486 (60%), Gaps = 35/486 (7%) Query 87 LRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAV-KPSLAWAETY-- 143 +RD V A+ +AA+D RV L+ + P A A QELR+A+ AF A K ++A+ +T+ Sbjct 71 VRDVVEALEKAAQDKRVKSLLVHIDQPGGVAVA-QELRDAVKAFRASGKKAVAFTDTFGE 129 Query 144 --PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 201 T +YYLA+AF E+++QPSG V L G A F RDA K G++ + R EYK+A Sbjct 130 GGSATGAYYLATAFDEIYIQPSGDVTLTGIAMETPFARDAFAKLGVQPRIGQRYEYKNAV 189 Query 202 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 261 N +TE G+T AHREA + L SL Q+ + +A+ R + D + L DRAPLL A+ Sbjct 190 NTYTEQGYTAAHREATEKFLGSLFGQLVRGIAEGRKLSEDEVKGLIDRAPLLGQAALEAK 249 Query 262 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP 321 L+D + +RD+ A++ E G G+Q +K YL R + Sbjct 250 LVDGLLYRDEVLAKVKEEAG--------KGAQLLFLDK----YLDRTGGA---------- 287 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLG-PSSAGGDTIAAALREVAADDSVSAIV 380 R T+A+V G IV RG + P G ++ G +++A ALR+ + D V AI+ Sbjct 288 ----REEGETVALVYGVGGIV--RGKSESNPFGGEATFGAESVALALRKASEDKEVKAIL 341 Query 381 LRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTIT 440 RVDSPGGS AS+T+ REV RAR++GKPV+ SM AASGGY+VSMGAD IVA PGT+T Sbjct 342 FRVDSPGGSYVASDTVRREVQRAREKGKPVIVSMATYAASGGYFVSMGADKIVAQPGTLT 401 Query 441 GSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDF 500 GSIGV GK+V D +LG+ + + +A +S D+ FTP+QQA +A D Y+DF Sbjct 402 GSIGVYGGKMVTADFWAKLGINFETISLGKDATLYSTDSDFTPEQQAKNDASLDRVYTDF 461 Query 501 VERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEV 560 ++ AEGR + + + VARGRVWTG DA + GLVDELGG A+ + A L +D +V Sbjct 462 TQKAAEGRHLPLEKLQAVARGRVWTGEDAKELGLVDELGGFPKALELVREAAKLPKDAKV 521 Query 561 RIVSYP 566 + +P Sbjct 522 HLQVFP 527 >gi|115375108|ref|ZP_01462376.1| signal peptide peptidase SppA, 67K type [Stigmatella aurantiaca DW4/3-1] gi|115367854|gb|EAU66821.1| signal peptide peptidase SppA, 67K type [Stigmatella aurantiaca DW4/3-1] Length=587 Score = 345 bits (885), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 205/486 (43%), Positives = 287/486 (60%), Gaps = 35/486 (7%) Query 87 LRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAFSAV-KPSLAWAETY-- 143 +RD V A+ +AA+D RV L+ + P A A QELR+A+ AF A K ++A+ +T+ Sbjct 60 VRDVVEALEKAAQDKRVKSLLVHIDQPGGVAVA-QELRDAVKAFRASGKKAVAFTDTFGE 118 Query 144 --PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAA 201 T +YYLA+AF E+++QPSG V L G A F RDA K G++ + R EYK+A Sbjct 119 GGSATGAYYLATAFDEIYIQPSGDVTLTGIAMETPFARDAFAKLGVQPRIGQRYEYKNAV 178 Query 202 NLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCG 261 N +TE G+T AHREA + L SL Q+ + +A+ R + D + L DRAPLL A+ Sbjct 179 NTYTEQGYTAAHREATEKFLGSLFGQLVRGIAEGRKLSEDEVKGLIDRAPLLGQAALEAK 238 Query 262 LIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVP 321 L+D + +RD+ A++ E G G+Q +K YL R + Sbjct 239 LVDGLLYRDEVLAKVKEEAG--------KGAQLLFLDK----YLDRTGGA---------- 276 Query 322 SIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLG-PSSAGGDTIAAALREVAADDSVSAIV 380 R T+A+V G IV RG + P G ++ G +++A ALR+ + D V AI+ Sbjct 277 ----REEGETVALVYGVGGIV--RGKSESNPFGGEATFGAESVALALRKASEDKEVKAIL 330 Query 381 LRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYVSMGADAIVANPGTIT 440 RVDSPGGS AS+T+ REV RAR++GKPV+ SM AASGGY+VSMGAD IVA PGT+T Sbjct 331 FRVDSPGGSYVASDTVRREVQRAREKGKPVIVSMATYAASGGYFVSMGADKIVAQPGTLT 390 Query 441 GSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDF 500 GSIGV GK+V D +LG+ + + +A +S D+ FTP+QQA +A D Y+DF Sbjct 391 GSIGVYGGKMVTADFWAKLGINFETISLGKDATLYSTDSDFTPEQQAKNDASLDRVYTDF 450 Query 501 VERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEV 560 ++ AEGR + + + VARGRVWTG DA + GLVDELGG A+ + A L +D +V Sbjct 451 TQKAAEGRHLPLEKLQAVARGRVWTGEDAKELGLVDELGGFPKALELVREAAKLPKDAKV 510 Query 561 RIVSYP 566 + +P Sbjct 511 HLQVFP 516 >gi|83310697|ref|YP_420961.1| periplasmic serine protease [Magnetospirillum magneticum AMB-1] gi|82945538|dbj|BAE50402.1| Periplasmic serine protease [Magnetospirillum magneticum AMB-1] Length=582 Score = 345 bits (885), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 221/564 (40%), Positives = 310/564 (55%), Gaps = 46/564 (8%) Query 56 CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPS 115 VL +L + +TT +PL +L+G R LR V A+ RAA D RV+G+ A + P Sbjct 47 MVLTLDLDAPFRDTTRENPLAMLSGE-RSYGLRQVVEALDRAAADSRVSGVFATLGHSPL 105 Query 116 PAGAVQELREAIAAFSAV-KPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVG 170 Q+LR+A+A F A KP++ +AET GTL YYLA+AF +VW+QPSG VGL G Sbjct 106 GLAGRQDLRDAVARFRASGKPAVLFAETLGEGGSGTLDYYLATAFSQVWLQPSGDVGLTG 165 Query 171 FATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQ 230 + F++ L GI+AQF R EYKSA ++FTE GFT AHRE + R+LDS +Q+ Sbjct 166 LWVESPFIKGTLDLLGIKAQFSGRHEYKSAIDMFTETGFTPAHRENLGRLLDSWSEQIVA 225 Query 231 AVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESS 290 +A +R + + EL + P L +A+ L+D++G+RD+A+ +A G+ K Sbjct 226 GIAAARGLPEPQVRELMGKGPFLASEALAARLVDKVGYRDEAWGMIA---GIGK------ 276 Query 291 GSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQF 350 +K M L YA+ RL P + V + G RG Sbjct 277 -------DKAEEMDLGDYAA----RLDHP----------KGVKVALISGIGAIHRGESHH 315 Query 351 LPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPV 410 G G T+A A R+ DD+V I+ RVDSPGGS AS+T+ EV RAR GK V Sbjct 316 GLDGDGDFGSQTVAEAFRDAVDDDAVKVILFRVDSPGGSYIASDTVHHEVERARKAGKKV 375 Query 411 VASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNA 470 V SMG AASGGY+V+MGAD I+A PGTITGSIGV TGK+V+ + +LG+ D + Sbjct 376 VVSMGNYAASGGYFVAMGADRIIAAPGTITGSIGVFTGKVVLDEFWKKLGISWDEMHRGD 435 Query 471 NADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADAL 530 NA WS + PF+ +A + D Y+DF + + R + +D +ARGR+WTGADA Sbjct 436 NAGMWSANQPFSSQAKARIDTLLDHIYADFTGKASAARNLDAARMDKLARGRIWTGADAK 495 Query 531 DRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDA 590 GLVD LGG A+ + + + GL D + +V +P RPR + A SL Sbjct 496 QSGLVDGLGGWAEALSQVRQVGGLKVDETLTLVEFP--------RPRKPWQVLAESL--G 545 Query 591 MGALLARSIVGIVEQVEQTLSGAS 614 G++ R I+ +E + L+ A+ Sbjct 546 GGSVAERRILARIEPLLDVLAPAA 569 >gi|297559382|ref|YP_003678356.1| signal peptide peptidase SppA, 36K type [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296843830|gb|ADH65850.1| signal peptide peptidase SppA, 36K type [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=562 Score = 335 bits (858), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 228/547 (42%), Positives = 296/547 (55%), Gaps = 37/547 (6%) Query 53 PNG-CVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQ 111 P G VLE +L + DP + + R L D + I R A DPRVA L+ RV Sbjct 14 PQGPLVLELDLTEGVADQAPGDPFSQIMNRRRQQYL-DVLEGIRRGARDPRVAALLVRVD 72 Query 112 LPPSPAGAVQELREAIAAFSAV-KPSLAWA----ETYPGTLSYYLASAFGEVWMQPSGSV 166 VQELR+ +A F A KP++AWA ET G L YYLA AF V M P+G + Sbjct 73 ARSLGFAKVQELRDTVADFRAAGKPAVAWADSFGETGEGNLPYYLACAFSRVVMAPTGVL 132 Query 167 GLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQD 226 GL G TF++ AL K + + AR EYK+A N TE G+T A REA R++ SL D Sbjct 133 GLTGLMMRTTFVKGALDKLDVSYEVGARHEYKNAMNSVTETGYTAAQREASDRIVTSLGD 192 Query 227 QVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARM-AELVGVEKG 285 Q+ +AV+ +R + + + L + P L +AV L+D + RD+ YA++ EL G Sbjct 193 QIVEAVSLARGLPREEVRALVSKGPFLAREAVEHKLVDGLAHRDEVYAQLFGELSG---- 248 Query 286 SPESSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR 345 +P ++ RY P R + IA+++ G I GR Sbjct 249 -------------EPQLQFVTRYHRKH------TAPQQLSRNTGGHIALISATGTISLGR 289 Query 346 GGPQFLPLGPSSA-GGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARAR 404 + PLG + G DT+AAA R D V A+V RVDS GGS TAS+ I RE Sbjct 290 --TRRSPLGGGTVMGSDTVAAAFRAARKDPQVKAVVFRVDSRGGSPTASDAIRRETELTS 347 Query 405 DRGKPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSD 464 G PVVA MG VAASGGYYV++G+DA+VA PGT+TGSIGVITGK V+ LK++ GV SD Sbjct 348 KAGIPVVAVMGDVAASGGYYVTLGSDAVVAQPGTLTGSIGVITGKPVLGALKEQYGVTSD 407 Query 465 AVRTNANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVW 524 +VRT +A + D PFT + A D Y DF +VA R MT + V VARGRVW Sbjct 408 SVRTGEHAGMFDTDRPFTESEWERVNALLDEIYEDFTGKVAAARGMTREQVHEVARGRVW 467 Query 525 TGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAA 584 TG DA +RGLVDELGGL TAVR A+ AG + + +P + D +R SS Sbjct 468 TGRDAHERGLVDELGGLETAVRLAREKAGAG---PLPVRPFPRPNPLDRIRQHESSEDVG 524 Query 585 ASLPDAM 591 AS P + Sbjct 525 ASGPQTV 531 >gi|328873642|gb|EGG22009.1| hypothetical protein DFA_01898 [Dictyostelium fasciculatum] Length=650 Score = 332 bits (850), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 198/531 (38%), Positives = 292/531 (55%), Gaps = 63/531 (11%) Query 72 FDPLTVLTGGGRP-----------MALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGA- 119 FD L V+T RP + D + I+ A+ D +V LI R+ + A Sbjct 57 FDLLEVVTT--RPNKIEQLFHPNTIYFYDIINYINHASGDAKVKALICRLSDKAHLSLAM 114 Query 120 VQELREAIAAFSAV-KPSLAWAETYPGTLS-----YYLASAFGEVWMQPSGSVGLVGFAT 173 +QELR+AI F A K ++ ++E++ G LS YYLA+AF E+++ G+VGLV F++ Sbjct 115 IQELRQAILNFRAKGKHTVVYSESF-GELSNSIGSYYLATAFNEIYIPQCGAVGLVSFSS 173 Query 174 NATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVA 233 + +F++ L K GI A+F R EYKSAA+ TE+ TD++RE++T +L + +Q++Q +A Sbjct 174 DQSFIKKTLDKLGITAEFFKRKEYKSAADPLTEEKLTDSNRESLTALLGDILNQMYQGIA 233 Query 234 KSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQ 293 K RN+G+D L + P + AV L++ + ++ Y + + + + Sbjct 234 KERNLGMDQLLNIISNGPYSSNKAVELNLVNGTKYLNETYEHLKKKM------------E 281 Query 294 TSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGR------GG 347 +KP +YL +Y S T P P ++SK A++ LEG I G+ GG Sbjct 282 EDHKKKPTLLYLTKYMS------TKPHPY--SQKSKHQFALINLEGAIYRGQSTDPMHGG 333 Query 348 PQFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRG 407 P S G +T++ ALR D ++ AIVL V+SPGGS AS+ I E+ A+ G Sbjct 334 P--------SIGSETVSLALRAATLDKNIKAIVLVVNSPGGSYIASDLIHHEIELAKKAG 385 Query 408 KPVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVR 467 K VV MG AASGGY+++ AD IVA PGTITGSIGV+ GK + + +++GV D + Sbjct 386 KKVVVHMGQFAASGGYFIACNADRIVALPGTITGSIGVLAGKFNTKPMWEKIGVTYDMIN 445 Query 468 TNAN-----ADAWSIDAPFTPDQQAHREAEADLF---YSDFVERVAEGRKMTTDAVDVVA 519 N N D + + P + R+A D Y DF +VA GR +T V+ VA Sbjct 446 LNNNDKHGDNDNSTFYSALHPYNKVQRDAMNDFLDYIYGDFTSKVAAGRTLTAAQVEDVA 505 Query 520 RGRVWTGADALDRGLVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSL 570 RGRVWTG ALDR LVD++G L A+ AK L GL E +++IV +P SL Sbjct 506 RGRVWTGNQALDRKLVDKIGSLNDAINEAKTLCGLKETDKLQIVEFPKESL 556 >gi|83593953|ref|YP_427705.1| peptidase S49 [Rhodospirillum rubrum ATCC 11170] gi|83576867|gb|ABC23418.1| Peptidase S49 [Rhodospirillum rubrum ATCC 11170] Length=593 Score = 331 bits (848), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 217/561 (39%), Positives = 297/561 (53%), Gaps = 35/561 (6%) Query 12 RALGGRWVRWVNMVAFLPSIPVVEDLRALVGRVDTARHHGVPNGCVLEFNLRSVPPETTG 71 R +G + +V L S+ +V AL + + +P VL+ + E G Sbjct 2 RFIGKALLVVFAVVGILASVLIVSGAVALSSFI--GKDEPLPTKLVLDLDASGSFSEDGG 59 Query 72 FDP-LTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLPPSPAGAVQELREAIAAF 130 P L L+G G +LR + AA DP V GL+ R+ QELR+AI AF Sbjct 60 ALPGLGFLSGEGERPSLRAVTEGLIAAASDPTVKGLMVRIGEGSLGMAQAQELRQAILAF 119 Query 131 SAV-KPSLAWAETY----PGTLSYYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKA 185 A KPS+A+AET GT+ YYLASA +VW+QPSG +G GFA F+R L Sbjct 120 RASGKPSIAYAETIGEFGQGTVPYYLASAVEDVWLQPSGMLGTTGFAVRMPFVRKLLDDL 179 Query 186 GIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDE 245 GI QF+AR E+K AA T+ G + A + ++ QV +AVA++R + D + Sbjct 180 GILPQFIARKEFKDAAATATQYGMSPAQEISFGALVQGWSGQVVRAVAEARGLSEDQVRG 239 Query 246 LADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPESSGSQTSPDEKPPRMYL 305 L DR+PLL +A+ GLIDR+G+ D+A M E G ++ + + Sbjct 240 LIDRSPLLAAEALESGLIDRLGYPDEARKAMGERAGTDE-----------------HLSV 282 Query 306 ARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGPQFLPLGPSSAGGDTIAA 365 +YA R P P G +A++ GPIV G G + P +AA Sbjct 283 GQYAE--RQAKAKPAPGAKG------LALIAASGPIVTGDG--KVSPFDGKEIDARALAA 332 Query 366 ALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGKPVVASMGAVAASGGYYV 425 + D V+AIVLR+DSPGGS S+ +WR V+RAR G PV+ASMG VAASGGYY+ Sbjct 333 TIDSAVDDAGVAAIVLRIDSPGGSYVGSDLVWRAVSRARQHGLPVIASMGDVAASGGYYM 392 Query 426 SMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANADAWSIDAPFTPDQ 485 +MGA+ IVA PGT+TGSIGV+ GK + + LG+ V NA +S+ PF Sbjct 393 AMGANKIVAQPGTLTGSIGVVAGKFTIAKASEDLGIAWGGVEAGRNAALFSLTDPFDEAG 452 Query 486 QAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRGLVDELGGLRTAV 545 Q + D Y+DF + A GR ++ +A++ ARGRVWTG DAL GLVD LGGL+TA+ Sbjct 453 QRRMDQILDAIYADFTGKAAAGRGLSPEAIEEAARGRVWTGEDALAHGLVDALGGLQTAI 512 Query 546 RRAKVLAGLDEDTEVRIVSYP 566 A+ AGLD + I YP Sbjct 513 ELARTEAGLDPHAPLAITVYP 533 >gi|336460640|gb|EGO39531.1| ClpP class periplasmic serine protease [Mycobacterium avium subsp. paratuberculosis S397] Length=210 Score = 323 bits (827), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 162/210 (78%), Positives = 184/210 (88%), Gaps = 0/210 (0%) Query 414 MGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRTNANAD 473 MGAVAASGGYYVS+ ADAIVANP TITGSIGVITGKLV+RDL RLGVGSD VRTNANAD Sbjct 1 MGAVAASGGYYVSVAADAIVANPATITGSIGVITGKLVIRDLLGRLGVGSDTVRTNANAD 60 Query 474 AWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGADALDRG 533 AWSIDAPFTP+Q+AHREAEADL Y+DFV RVAEGR +TTDAV+ VARGRVWTGADA +RG Sbjct 61 AWSIDAPFTPEQRAHREAEADLVYTDFVSRVAEGRNLTTDAVERVARGRVWTGADAHERG 120 Query 534 LVDELGGLRTAVRRAKVLAGLDEDTEVRIVSYPGSSLWDMVRPRPSSRPAAASLPDAMGA 593 LVDELGG R AVRRAK+LAGLDED +VRIV+YP SL D++RPR SS+PAA SLPDA+GA Sbjct 121 LVDELGGFRIAVRRAKILAGLDEDADVRIVTYPSGSLLDVLRPRASSQPAAVSLPDALGA 180 Query 594 LLARSIVGIVEQVEQTLSGASVLWLGESRL 623 L +++ I++ VE++ SGAS LWLG SRL Sbjct 181 LTVKTLGAILDNVERSCSGASALWLGPSRL 210 Score = 37.7 bits (86), Expect = 6.2, Method: Compositional matrix adjust. Identities = 38/139 (28%), Positives = 61/139 (44%), Gaps = 8/139 (5%) Query 149 YYLASAFGEVWMQPSGSVGLVGFATNATFLRDALHKAGIEAQFVARGEYKSAANL---FT 205 YY++ A + P+ G +G T +RD L + G+ + V A ++ FT Sbjct 10 YYVSVAADAIVANPATITGSIGVITGKLVIRDLLGRLGVGSDTVRTNANADAWSIDAPFT 69 Query 206 EDGFTDAHREAVTRMLDSLQDQVWQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDR 265 + AHREA D + VA+ RN+ DA++ +A DA GL+D Sbjct 70 PE--QRAHREAEA---DLVYTDFVSRVAEGRNLTTDAVERVARGRVWTGADAHERGLVDE 124 Query 266 IGFRDQAYARMAELVGVEK 284 +G A R L G+++ Sbjct 125 LGGFRIAVRRAKILAGLDE 143 >gi|336115962|ref|YP_004570728.1| putative signal peptide peptidase [Microlunatus phosphovorus NM-1] gi|334683740|dbj|BAK33325.1| putative signal peptide peptidase [Microlunatus phosphovorus NM-1] Length=568 Score = 320 bits (819), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 216/509 (43%), Positives = 286/509 (57%), Gaps = 34/509 (6%) Query 54 NGCVLEFNLRSVPPETTGFDPLTVLTGGGRPMALRDAVAAIHRAAEDPRVAGLIARVQLP 113 + +LE +L E DPL L G+ LR + A+H AA D RV GL+A+V P Sbjct 30 SSIILELDLTQPLVEPDPADPLAPLLSRGQ-RQLRPTIKALHEAAADHRVVGLLAKVGGP 88 Query 114 PSPAGAVQELREAIAAFSAV-KPSLAWAETYP----GTLSYYLASAFGEVWMQPSGSVGL 168 S A V ELR + AF V KP++AWAE++P GT +Y LAS FGEVW+QP G +GL Sbjct 89 LSWA-TVHELRRGLQAFLDVGKPTVAWAESFPDGAAGTGAYVLASGFGEVWLQPGGGLGL 147 Query 169 VGFATNATFLRDALHKAGIEAQFVARGEYKSAANLFTEDGFTDAHREAVTRMLDSLQDQV 228 +G + TFLR A K G+E Q R EYK+AA+ FT FT+ HRE++ + S+ Sbjct 148 LGVSIETTFLRGAFDKLGMEPQLGQRYEYKNAADRFTRTEFTEPHRESMEALAASVYADA 207 Query 229 WQAVAKSRNIGVDALDELADRAPLLRDDAVTCGLIDRIGFRDQAYARMAELVGVEKGSPE 288 +A R++ + + EL D P ++A+ L+DR+G+RD+ A VG Sbjct 208 IALIAAGRSMTPERVRELVDTGPRTAEEALAARLVDRLGYRDEVLASFRAHVG------- 260 Query 289 SSGSQTSPDEKPPRMYLARYASSARPRLTPPVPSIPGRRSKPTIAVVTLEGPIVNGRGGP 348 + ++ R+ R RL +A+V + G I +GR P Sbjct 261 ---------DDAELLFADRWKPRRRLRLPARRRG--------HLALVEVRGGIGSGRSRP 303 Query 349 QFLPLGPSSAGGDTIAAALREVAADDSVSAIVLRVDSPGGSVTASETIWREVARARDRGK 408 P+G G DT+A+ LR DD ++LRV+SPGGS ASE IWREV R ++ GK Sbjct 304 G--PIG-GQTGSDTVASQLRAALEDDRAHGVLLRVNSPGGSAVASEVIWREVCRVKEAGK 360 Query 409 PVVASMGAVAASGGYYVSMGADAIVANPGTITGSIGVITGKLVVRDLKDRLGVGSDAVRT 468 PVV SMG VAASGGYYVS A IVA P T+TGSIGV+ GK V+ L DRLG+ + AV Sbjct 361 PVVVSMGDVAASGGYYVSCAATTIVALPTTLTGSIGVLGGKFVISGLLDRLGLSTGAVHE 420 Query 469 NANADAWSIDAPFTPDQQAHREAEADLFYSDFVERVAEGRKMTTDAVDVVARGRVWTGAD 528 +A WS F ++ +AE D Y+ FV +VA GR T ++ +ARGRVWTG D Sbjct 421 GEHARMWSARRGFDDGERERLDAELDAIYAAFVAKVAAGRGRTVAEIEPLARGRVWTGRD 480 Query 529 ALDRGLVDELGGLRTAVRRAKVLAGLDED 557 A DRGLVD+LGGLR AV A+ LA L D Sbjct 481 AYDRGLVDQLGGLREAVTTARRLAELPAD 509 Lambda K H 0.318 0.134 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1429258453920 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40