BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0728c Length=326 Score E Sequences producing significant alignments: (Bits) Value gi|15607868|ref|NP_215242.1| D-3-phosphoglycerate dehydrogenase ... 636 2e-180 gi|31791914|ref|NP_854407.1| D-3-phosphoglycerate dehydrogenase ... 634 8e-180 gi|340625749|ref|YP_004744201.1| putative D-3-phosphoglycerate d... 632 2e-179 gi|289446288|ref|ZP_06436032.1| D-3-phosphoglycerate dehydrogena... 631 4e-179 gi|308396518|ref|ZP_07492346.2| D-3-phosphoglycerate dehydrogena... 614 7e-174 gi|339293753|gb|AEJ45864.1| D-3-phosphoglycerate dehydrogenase [... 612 3e-173 gi|289744452|ref|ZP_06503830.1| D-3-phosphoglycerate dehydrogena... 608 4e-172 gi|240167739|ref|ZP_04746398.1| putative D-3-phosphoglycerate de... 533 2e-149 gi|254818392|ref|ZP_05223393.1| 2-hydroxyacid dehydrogenase fami... 533 2e-149 gi|342861825|ref|ZP_08718470.1| D-3-phosphoglycerate dehydrogena... 524 1e-146 gi|118464026|ref|YP_883573.1| 2-hydroxyacid dehydrogenase [Mycob... 518 4e-145 gi|336460634|gb|EGO39525.1| phosphoglycerate dehydrogenase-like ... 518 6e-145 gi|296168590|ref|ZP_06850394.1| D-3-phosphoglycerate dehydrogena... 516 2e-144 gi|183981085|ref|YP_001849376.1| D-3-phosphoglycerate dehydrogen... 508 6e-142 gi|41410292|ref|NP_963128.1| hypothetical protein MAP4194c [Myco... 507 1e-141 gi|118616602|ref|YP_904934.1| D-3-phosphoglycerate dehydrogenase... 506 2e-141 gi|289568673|ref|ZP_06448900.1| D-3-phosphoglycerate dehydrogena... 415 5e-114 gi|289749235|ref|ZP_06508613.1| D-3-phosphoglycerate dehydrogena... 327 1e-87 gi|240168710|ref|ZP_04747369.1| autoinducer-2 (AI-2) kinase [Myc... 233 5e-59 gi|302338895|ref|YP_003804101.1| D-isomer specific 2-hydroxyacid... 203 3e-50 gi|309777701|ref|ZP_07672651.1| D-3-phosphoglycerate dehydrogena... 202 5e-50 gi|313901317|ref|ZP_07834804.1| 4-phosphoerythronate dehydrogena... 199 6e-49 gi|269839501|ref|YP_003324193.1| D-isomer specific 2-hydroxyacid... 191 2e-46 gi|119719732|ref|YP_920227.1| glyoxylate reductase [Thermofilum ... 190 3e-46 gi|332798442|ref|YP_004459941.1| phosphoglycerate dehydrogenase ... 188 1e-45 gi|255533386|ref|YP_003093758.1| NAD-binding D-isomer specific 2... 188 1e-45 gi|167759501|ref|ZP_02431628.1| hypothetical protein CLOSCI_0184... 188 1e-45 gi|154686308|ref|YP_001421469.1| YoaD [Bacillus amyloliquefacien... 188 1e-45 gi|305662806|ref|YP_003859094.1| Glyoxylate reductase [Ignisphae... 187 2e-45 gi|332296720|ref|YP_004438642.1| Phosphoglycerate dehydrogenase ... 186 4e-45 gi|16078917|ref|NP_389738.1| 2-hydroxyacid dehydrogenase [Bacill... 186 4e-45 gi|328553215|gb|AEB23707.1| YoaD [Bacillus amyloliquefaciens TA2... 184 2e-44 gi|311068575|ref|YP_003973498.1| putative 2-hydroxyacid dehydrog... 183 3e-44 gi|170750794|ref|YP_001757054.1| NAD-binding D-isomer specific 2... 183 3e-44 gi|328912008|gb|AEB63604.1| D-3-phosphoglycerate dehydrogenase [... 182 5e-44 gi|321311502|ref|YP_004203789.1| putative 2-hydroxyacid dehydrog... 181 1e-43 gi|289523731|ref|ZP_06440585.1| D-3-phosphoglycerate dehydrogena... 180 3e-43 gi|302347920|ref|YP_003815558.1| Glyoxylate reductase [Acidilobu... 178 9e-43 gi|312129155|ref|YP_003996495.1| d-isomer specific 2-hydroxyacid... 178 9e-43 gi|312137068|ref|YP_004004405.1| d-3-phosphoglycerate dehydrogen... 178 1e-42 gi|20808958|ref|NP_624129.1| D-3-phosphoglycerate dehydrogenase ... 177 1e-42 gi|238763451|ref|ZP_04624414.1| D-3-phosphoglycerate dehydrogena... 177 2e-42 gi|315925550|ref|ZP_07921760.1| D-3-phosphoglycerate dehydrogena... 177 2e-42 gi|291299076|ref|YP_003510354.1| phosphoglycerate dehydrogenase ... 177 2e-42 gi|148508253|gb|ABQ76039.1| phosphoglycerate dehydrogenase [uncu... 177 3e-42 gi|255036888|ref|YP_003087509.1| NAD-binding D-isomer specific 2... 177 3e-42 gi|123442827|ref|YP_001006803.1| putative oxidoreductase [Yersin... 176 3e-42 gi|333980430|ref|YP_004518375.1| phosphoglycerate dehydrogenase ... 176 4e-42 gi|320531069|ref|ZP_08032098.1| 4-phosphoerythronate dehydrogena... 176 5e-42 gi|110668011|ref|YP_657822.1| phosphoglycerate dehydrogenase [Ha... 176 6e-42 >gi|15607868|ref|NP_215242.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15840135|ref|NP_335172.1| 2-hydroxyacid dehydrogenase family protein [Mycobacterium tuberculosis CDC1551] gi|148660503|ref|YP_001282026.1| 2-hydroxyacid dehydrogenase family protein [Mycobacterium tuberculosis H37Ra] 45 more sequence titles Length=326 Score = 636 bits (1640), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 325/326 (99%), Positives = 326/326 (100%), Gaps = 0/326 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +TPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 1 MTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR Sbjct 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ Sbjct 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR Sbjct 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 MVADDLGALLSGNRPAHVVNPEVLGS Sbjct 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 >gi|31791914|ref|NP_854407.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium bovis AF2122/97] gi|121636650|ref|YP_976873.1| putative D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989122|ref|YP_002643809.1| putative D-3-phosphoglycerate dehydrogenase [Mycobacterium bovis BCG str. Tokyo 172] 18 more sequence titles Length=326 Score = 634 bits (1634), Expect = 8e-180, Method: Compositional matrix adjust. Identities = 324/326 (99%), Positives = 325/326 (99%), Gaps = 0/326 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +TPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 1 MTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR Sbjct 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ Sbjct 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR Sbjct 241 LHDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 MVADDLGALLSGNRPAHVVNPEVLGS Sbjct 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 >gi|340625749|ref|YP_004744201.1| putative D-3-phosphoglycerate dehydrogenase SERA2 [Mycobacterium canettii CIPT 140010059] gi|340003939|emb|CCC43073.1| putative D-3-phosphoglycerate dehydrogenase SERA2 (phosphoglycerate dehydrogenase) (PGDH) [Mycobacterium canettii CIPT 140010059] Length=326 Score = 632 bits (1630), Expect = 2e-179, Method: Compositional matrix adjust. Identities = 322/326 (99%), Positives = 325/326 (99%), Gaps = 0/326 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +TPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 1 MTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 VARHL+PADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR Sbjct 121 VARHLVPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDT+GMIGAQQFAAMRDGAVFLNTARSQ Sbjct 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTLGMIGAQQFAAMRDGAVFLNTARSQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR Sbjct 241 LHDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 MVADDLGALLSGNRPAHVVNPEVLGS Sbjct 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 >gi|289446288|ref|ZP_06436032.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis CPHL_A] gi|289419246|gb|EFD16447.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis CPHL_A] Length=326 Score = 631 bits (1628), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 323/326 (99%), Positives = 324/326 (99%), Gaps = 0/326 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +TPRPRALVTAPL GPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 1 MTPRPRALVTAPLCGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR Sbjct 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ Sbjct 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR Sbjct 241 LHDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 MVADDLGALLSGNRPAHVVNPEVLGS Sbjct 301 MVADDLGALLSGNRPAHVVNPEVLGS 326 >gi|308396518|ref|ZP_07492346.2| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis SUMu012] gi|308367103|gb|EFP55954.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis SUMu012] Length=314 Score = 614 bits (1583), Expect = 7e-174, Method: Compositional matrix adjust. Identities = 313/314 (99%), Positives = 314/314 (100%), Gaps = 0/314 (0%) Query 13 LRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER 72 +RGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER Sbjct 1 MRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER 60 Query 73 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV 132 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV Sbjct 61 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV 120 Query 133 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG 192 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG Sbjct 121 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG 180 Query 193 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALR 252 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALR Sbjct 181 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALR 240 Query 253 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG 312 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG Sbjct 241 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG 300 Query 313 NRPAHVVNPEVLGS 326 NRPAHVVNPEVLGS Sbjct 301 NRPAHVVNPEVLGS 314 >gi|339293753|gb|AEJ45864.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium tuberculosis CCDC5079] gi|339297392|gb|AEJ49502.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium tuberculosis CCDC5180] Length=314 Score = 612 bits (1577), Expect = 3e-173, Method: Compositional matrix adjust. Identities = 312/314 (99%), Positives = 313/314 (99%), Gaps = 0/314 (0%) Query 13 LRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER 72 +RGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER Sbjct 1 MRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGGPVFER 60 Query 73 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV 132 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV Sbjct 61 GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADV 120 Query 133 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG 192 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG Sbjct 121 RSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAG 180 Query 193 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALR 252 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQL DTDALVDALR Sbjct 181 HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLHDTDALVDALR 240 Query 253 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG 312 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG Sbjct 241 GGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSG 300 Query 313 NRPAHVVNPEVLGS 326 NRPAHVVNPEVLGS Sbjct 301 NRPAHVVNPEVLGS 314 >gi|289744452|ref|ZP_06503830.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis 02_1987] gi|289684980|gb|EFD52468.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis 02_1987] Length=329 Score = 608 bits (1567), Expect = 4e-172, Method: Compositional matrix adjust. Identities = 311/316 (99%), Positives = 313/316 (99%), Gaps = 0/316 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +TPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 1 MTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR Sbjct 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ Sbjct 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR Sbjct 241 LHDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 Query 301 MVADDLGALLSGNRPA 316 MVADDLGALLSG P+ Sbjct 301 MVADDLGALLSGTYPS 316 >gi|240167739|ref|ZP_04746398.1| putative D-3-phosphoglycerate dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=329 Score = 533 bits (1372), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 268/329 (82%), Positives = 295/329 (90%), Gaps = 3/329 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T RPRALVTAPLRGPG A+L+ LADVVYDPWIDQ PLRIY+AEQLA+RIT AAD++VV Sbjct 1 MTSRPRALVTAPLRGPGLAKLQHLADVVYDPWIDQNPLRIYNAEQLAERITVEAADIVVV 60 Query 61 ESDSVGGPVFE---RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVAL 117 ESDS+ GPVFE R L VAATRGDP+NVDI GATAAGIPVL+TPARNADAVAEMTVAL Sbjct 61 ESDSISGPVFEQRSRPLIAVAATRGDPNNVDIAGATAAGIPVLNTPARNADAVAEMTVAL 120 Query 118 LLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGL 177 LL V RH++ ADA+VRSGN+FRDGTIPYQRFRG EIAGLTAGLVGLGAVGRA+RWRL+GL Sbjct 121 LLTVTRHVLTADAEVRSGNVFRDGTIPYQRFRGWEIAGLTAGLVGLGAVGRALRWRLTGL 180 Query 178 GLRVIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTA 237 GLRVIAHDPY D+A H LDELLAE+D+VS+HA VTD+T GMIGA+QFAAMRDG VFLNTA Sbjct 181 GLRVIAHDPYSDEARHGLDELLAESDVVSLHAPVTDETAGMIGAEQFAAMRDGVVFLNTA 240 Query 238 RSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEAR 297 R+QL D ALVDALR GK+AAAGLDHF GEWLP DHPL MPNVVLTPHIGGATWNTEAR Sbjct 241 RAQLHDIVALVDALRSGKVAAAGLDHFAGEWLPADHPLTGMPNVVLTPHIGGATWNTEAR 300 Query 298 QARMVADDLGALLSGNRPAHVVNPEVLGS 326 QA++VADDL ALLSGNRP H+VNPEVLGS Sbjct 301 QAQLVADDLEALLSGNRPTHIVNPEVLGS 329 >gi|254818392|ref|ZP_05223393.1| 2-hydroxyacid dehydrogenase family protein [Mycobacterium intracellulare ATCC 13950] Length=326 Score = 533 bits (1372), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 266/325 (82%), Positives = 293/325 (91%), Gaps = 0/325 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T +PRALVTAP+RGPGFA+LR LADV+YDPWI+Q PLRIYSAEQLA+RI + A+++VV Sbjct 1 MTSKPRALVTAPMRGPGFAKLRELADVIYDPWIEQTPLRIYSAEQLAERIASEGAEIVVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSV GPVF +GLR +A+TRGDP+NVDI GATAAGIPVL+TPARNADAVAEMTVALLLA Sbjct 61 ESDSVRGPVFAQGLRAIASTRGDPNNVDIAGATAAGIPVLNTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RH++PADADVRSGNIFRDG+IPYQRFRG EIAG TAGLVGLGAVGRA +WRLSGLGLR Sbjct 121 ATRHVLPADADVRSGNIFRDGSIPYQRFRGGEIAGRTAGLVGLGAVGRATQWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPY DA HSLDELLAEA+IVS+HA VTDDT GMIGA QFAAMRDG VFLNTAR+Q Sbjct 181 VIAHDPYNPDARHSLDELLAEAEIVSLHAPVTDDTAGMIGAGQFAAMRDGVVFLNTARAQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDAL GK+AAAGLDHF GEWLP DHPLV M NVVLTPHIGGATWNTEARQA+ Sbjct 241 LHDTDALVDALVAGKVAAAGLDHFAGEWLPADHPLVGMANVVLTPHIGGATWNTEARQAQ 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLG 325 MVADDL ALL G+ PAH+VNPEVLG Sbjct 301 MVADDLEALLKGDAPAHLVNPEVLG 325 >gi|342861825|ref|ZP_08718470.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium colombiense CECT 3035] gi|342130642|gb|EGT83946.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium colombiense CECT 3035] Length=326 Score = 524 bits (1349), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 261/325 (81%), Positives = 294/325 (91%), Gaps = 0/325 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T +PRALVTAP+RGPGFA+LR LADVVYDPWI+Q PLRIYS EQLA+RI AA+++VV Sbjct 1 MTSKPRALVTAPMRGPGFAKLRELADVVYDPWIEQTPLRIYSPEQLAERIAGEAAEIVVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSV GPVFERG+RV+A+TRGDP+NVDI GATAAGIPVL+TPARNADAVAEMTVALLLA Sbjct 61 ESDSVRGPVFERGVRVIASTRGDPNNVDIAGATAAGIPVLNTPARNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RH++ ADADVRSGNIFRDG+IPYQRFR AEIAGLTAGLVGLGAVGRA +WRLSGLG+R Sbjct 121 ATRHVLAADADVRSGNIFRDGSIPYQRFRAAEIAGLTAGLVGLGAVGRATQWRLSGLGMR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIA DPY +A HSLD+LL EAD+VS+HA VTDDT GMIGA++FAAMRDG VFLNTAR+Q Sbjct 181 VIACDPYNPEARHSLDKLLGEADVVSLHAPVTDDTAGMIGAREFAAMRDGVVFLNTARAQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALVDAL GK+ AAGLDHF GEWLP DHPLV+M NVVLTPHIGGAT++TEARQA+ Sbjct 241 LHDTDALVDALVAGKVGAAGLDHFAGEWLPADHPLVAMGNVVLTPHIGGATFDTEARQAQ 300 Query 301 MVADDLGALLSGNRPAHVVNPEVLG 325 MVADDL ALL+GN PAH+VNPEVLG Sbjct 301 MVADDLEALLAGNAPAHIVNPEVLG 325 >gi|118464026|ref|YP_883573.1| 2-hydroxyacid dehydrogenase [Mycobacterium avium 104] gi|254776873|ref|ZP_05218389.1| 2-hydroxyacid dehydrogenase family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118165313|gb|ABK66210.1| 2-hydroxyacid dehydrogenase family protein [Mycobacterium avium 104] Length=326 Score = 518 bits (1335), Expect = 4e-145, Method: Compositional matrix adjust. Identities = 265/324 (82%), Positives = 293/324 (91%), Gaps = 0/324 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T +PRALVTAPLRGPG +LR LA+VVYDPWI+QRPLRIYSAEQLA+RI A A+++VV Sbjct 1 MTSKPRALVTAPLRGPGLDKLRALAEVVYDPWIEQRPLRIYSAEQLAERIAAEEAEIVVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSV GPVFE G+R +AATRGDP+NVDI GATAAGIPVL+TP RNADAVAEMTVALLLA Sbjct 61 ESDSVRGPVFELGVRAIAATRGDPNNVDIDGATAAGIPVLNTPGRNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RHL+PADADVR GNIFRDG+IPYQRFRG EIAGLTAGLVGLGAVGRA RWRLSGLGLR Sbjct 121 ATRHLLPADADVRGGNIFRDGSIPYQRFRGGEIAGLTAGLVGLGAVGRATRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPY +A H LDELLAE+D+VS+HA VTD+T GMIGA+QFAAMRDG VFLNTAR+Q Sbjct 181 VIAHDPYHPEARHGLDELLAESDVVSLHAPVTDETTGMIGAEQFAAMRDGVVFLNTARAQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALV+ALR GK+AAAGLDHF GEWLPTDHPLV MPNVVLTPHIGGATWNTEARQA+ Sbjct 241 LHDTDALVEALRAGKVAAAGLDHFVGEWLPTDHPLVGMPNVVLTPHIGGATWNTEARQAQ 300 Query 301 MVADDLGALLSGNRPAHVVNPEVL 324 +VADDL ALL+G PAH+VNPEVL Sbjct 301 LVADDLEALLAGATPAHIVNPEVL 324 >gi|336460634|gb|EGO39525.1| phosphoglycerate dehydrogenase-like oxidoreductase [Mycobacterium avium subsp. paratuberculosis S397] Length=326 Score = 518 bits (1333), Expect = 6e-145, Method: Compositional matrix adjust. Identities = 265/324 (82%), Positives = 293/324 (91%), Gaps = 0/324 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T +PRALVTAPLRGPG +LR LA+VVYDPWI+QRPLRIYSAEQLA+RI A A+++VV Sbjct 1 MTSKPRALVTAPLRGPGLDKLRVLAEVVYDPWIEQRPLRIYSAEQLAERIAAEEAEIVVV 60 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSV GPVFE G+R +AATRGDP+NVDI GATAAGIPVL+TP RNADAVAEMTVALLLA Sbjct 61 ESDSVRGPVFELGVRAIAATRGDPNNVDIDGATAAGIPVLNTPGRNADAVAEMTVALLLA 120 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RHL+PADADVR GNIFRDG+IPYQRFRG EIAGLTAGLVGLGAVGRA RWRLSGLGLR Sbjct 121 ATRHLLPADADVRGGNIFRDGSIPYQRFRGGEIAGLTAGLVGLGAVGRATRWRLSGLGLR 180 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPY +A H LDELLAE+D+VS+HA VTD+T GMIGA+QFAAMRDG VFLNTAR+Q Sbjct 181 VIAHDPYHPEARHGLDELLAESDVVSLHAPVTDETTGMIGAEQFAAMRDGVVFLNTARAQ 240 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALV+ALR GK+AAAGLDHF GEWLPTDHPLV MPNVVLTPHIGGATWNTEARQA+ Sbjct 241 LHDTDALVEALRAGKVAAAGLDHFVGEWLPTDHPLVGMPNVVLTPHIGGATWNTEARQAQ 300 Query 301 MVADDLGALLSGNRPAHVVNPEVL 324 +VADDL ALL+G PAH+VNPEVL Sbjct 301 LVADDLEALLAGATPAHIVNPEVL 324 >gi|296168590|ref|ZP_06850394.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896653|gb|EFG76292.1| D-3-phosphoglycerate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=319 Score = 516 bits (1329), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 267/318 (84%), Positives = 291/318 (92%), Gaps = 0/318 (0%) Query 8 LVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVGG 67 +VTAPLRG GFA+LR L DVVYDPWI+Q PLRIYSAEQLA+RI+A +ADV+VVESDSV G Sbjct 1 MVTAPLRGAGFAKLRELVDVVYDPWIEQTPLRIYSAEQLAERISAESADVVVVESDSVAG 60 Query 68 PVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIP 127 PVFERGLRVVA+TRGDP+NVDI GATAAG+PVL+TP RNADAVAEMTVALLL R L+P Sbjct 61 PVFERGLRVVASTRGDPNNVDIAGATAAGVPVLNTPGRNADAVAEMTVALLLVTTRQLLP 120 Query 128 ADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPY 187 ADADVRSGNIFRDG+IPYQRFRG E+AGLTAGLVGLGAVGRA RWRL+GLGLRVIAHDPY Sbjct 121 ADADVRSGNIFRDGSIPYQRFRGWEVAGLTAGLVGLGAVGRATRWRLAGLGLRVIAHDPY 180 Query 188 RDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDAL 247 DDA H LDELL EAD+VSMHA VT+DT+GMIGA+QFAAMRDG VFLNTAR+QL DTDAL Sbjct 181 NDDARHGLDELLDEADVVSMHAPVTEDTVGMIGAEQFAAMRDGVVFLNTARAQLHDTDAL 240 Query 248 VDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLG 307 V ALR GK+AAAGLDHF GEWLPTDHPLV MPNVVLTPHIGGATWNTEARQA+MVADDL Sbjct 241 VGALRDGKVAAAGLDHFVGEWLPTDHPLVGMPNVVLTPHIGGATWNTEARQAQMVADDLE 300 Query 308 ALLSGNRPAHVVNPEVLG 325 ALL+GN PAH+VNPEVLG Sbjct 301 ALLAGNAPAHIVNPEVLG 318 >gi|183981085|ref|YP_001849376.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium marinum M] gi|183174411|gb|ACC39521.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium marinum M] Length=329 Score = 508 bits (1308), Expect = 6e-142, Method: Compositional matrix adjust. Identities = 258/324 (80%), Positives = 283/324 (88%), Gaps = 3/324 (0%) Query 4 RPRALVTAPLRGPGFAQLRRLADVVYDPWIDQR---PLRIYSAEQLADRITAVAADVLVV 60 RPRALVTAPLRG G +LR+L DVVYDPWI + PLRIYSAEQLA+RIT+ + D++VV Sbjct 4 RPRALVTAPLRGSGLDKLRQLVDVVYDPWIGELEGGPLRIYSAEQLAERITSESVDIVVV 63 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 E+DSV G V + GLR + +TRGDP+NVDI GATAAGIPVL+TPARNADAVAEMTVALLLA Sbjct 64 EADSVSGAVLQLGLRAIFSTRGDPNNVDIAGATAAGIPVLNTPARNADAVAEMTVALLLA 123 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RHL+ ADADVRSGNIF DGTIPYQRFRG EIAG TAGLVGLGAVGRA WRL+GLGLR Sbjct 124 STRHLLTADADVRSGNIFHDGTIPYQRFRGWEIAGRTAGLVGLGAVGRATAWRLTGLGLR 183 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPY DA H L ELLAE+DIVS+HA VTDDT+GMIGAQQFA+MRDGAVFLNTAR+Q Sbjct 184 VIAHDPYCADARHGLAELLAESDIVSLHAPVTDDTVGMIGAQQFASMRDGAVFLNTARAQ 243 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALV ALR GK+AAAGLDHF GEWLPTDHPL SMPNVVLTPHIGGATWNTEARQA+ Sbjct 244 LHDTDALVQALRAGKVAAAGLDHFVGEWLPTDHPLASMPNVVLTPHIGGATWNTEARQAQ 303 Query 301 MVADDLGALLSGNRPAHVVNPEVL 324 MVAD L ALLSG RP H++NPEVL Sbjct 304 MVADGLQALLSGTRPTHILNPEVL 327 >gi|41410292|ref|NP_963128.1| hypothetical protein MAP4194c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41399126|gb|AAS06744.1| hypothetical protein MAP_4194c [Mycobacterium avium subsp. paratuberculosis K-10] Length=327 Score = 507 bits (1305), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 264/325 (82%), Positives = 292/325 (90%), Gaps = 1/325 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 +T +PRALVTAPLRGPG +LR LA+VVYDPWI+QRPLRIYSAEQLA+RI A A+++VV Sbjct 1 MTSKPRALVTAPLRGPGLDKLRVLAEVVYDPWIEQRPLRIYSAEQLAERIAAEEAEIVVV 60 Query 61 E-SDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLL 119 SDSV GPVFE G+R +AATRGDP+NVDI GATAAGIPVL+TP RNADAVAEMTVALLL Sbjct 61 VESDSVRGPVFELGVRAIAATRGDPNNVDIDGATAAGIPVLNTPGRNADAVAEMTVALLL 120 Query 120 AVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGL 179 A RHL+PADADVR GNIFRDG+IPYQRFRG EIAGLTAGLVGLGAVGRA RWRLSGLGL Sbjct 121 AATRHLLPADADVRGGNIFRDGSIPYQRFRGGEIAGLTAGLVGLGAVGRATRWRLSGLGL 180 Query 180 RVIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 RVIAHDPY +A H LDELLAE+D+VS+HA VTD+T GMIGA+QFAAMRDG VFLNTAR+ Sbjct 181 RVIAHDPYHPEARHGLDELLAESDVVSLHAPVTDETTGMIGAEQFAAMRDGVVFLNTARA 240 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQA 299 QL DTDALV+ALR GK+AAAGLDHF GEWLPTDHPLV MPNVVLTPHIGGATWNTEARQA Sbjct 241 QLHDTDALVEALRAGKVAAAGLDHFVGEWLPTDHPLVGMPNVVLTPHIGGATWNTEARQA 300 Query 300 RMVADDLGALLSGNRPAHVVNPEVL 324 ++VADDL ALL+G PAH+VNPEVL Sbjct 301 QLVADDLEALLAGATPAHIVNPEVL 325 >gi|118616602|ref|YP_904934.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium ulcerans Agy99] gi|118568712|gb|ABL03463.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium ulcerans Agy99] Length=329 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 258/324 (80%), Positives = 283/324 (88%), Gaps = 3/324 (0%) Query 4 RPRALVTAPLRGPGFAQLRRLADVVYDPWI---DQRPLRIYSAEQLADRITAVAADVLVV 60 RPRALVTAPLRG G +LR+L DVVYDPWI + PLRIYSAEQLA+RIT+ + D++VV Sbjct 4 RPRALVTAPLRGSGLDKLRQLVDVVYDPWIGGLEGGPLRIYSAEQLAERITSESVDIVVV 63 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 E+DSV G V + GLR + +TRGDP+NVDI GATAAGIPVL+TPARNADAVAEMTVALLLA Sbjct 64 EADSVSGAVLQLGLRAIFSTRGDPNNVDIAGATAAGIPVLNTPARNADAVAEMTVALLLA 123 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RHL+ ADADVRSGNIFRDGTIPYQRFRG EIAG TAGLVGLGAVGRA WRL+GLGL Sbjct 124 STRHLLTADADVRSGNIFRDGTIPYQRFRGWEIAGRTAGLVGLGAVGRATAWRLTGLGLW 183 Query 181 VIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQ 240 VIAHDPY DA H L ELLAE+DIVS+HA VTDDT+GMIGAQQFA+MRDGAVFLNTAR+Q Sbjct 184 VIAHDPYCADARHGLAELLAESDIVSLHAPVTDDTVGMIGAQQFASMRDGAVFLNTARAQ 243 Query 241 LRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQAR 300 L DTDALV ALR GK+AAAGLDHF GEWLPTDHPL SMPNVVLTPHIGGATWNTEARQA+ Sbjct 244 LHDTDALVQALRAGKVAAAGLDHFVGEWLPTDHPLASMPNVVLTPHIGGATWNTEARQAQ 303 Query 301 MVADDLGALLSGNRPAHVVNPEVL 324 MVAD L ALLSG RP H++NPEVL Sbjct 304 MVADGLQALLSGTRPTHILNPEVL 327 >gi|289568673|ref|ZP_06448900.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium tuberculosis T17] gi|289542427|gb|EFD46075.1| D-3-phosphoglycerate dehydrogenase SerA2 [Mycobacterium tuberculosis T17] Length=212 Score = 415 bits (1067), Expect = 5e-114, Method: Compositional matrix adjust. Identities = 210/212 (99%), Positives = 211/212 (99%), Gaps = 0/212 (0%) Query 115 VALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRL 174 +ALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRL Sbjct 1 MALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRL 60 Query 175 SGLGLRVIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFL 234 SGLGLRVIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFL Sbjct 61 SGLGLRVIAHDPYRDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFL 120 Query 235 NTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNT 294 NTARSQL DTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNT Sbjct 121 NTARSQLHDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNT 180 Query 295 EARQARMVADDLGALLSGNRPAHVVNPEVLGS 326 EARQARMVADDLGALLSGNRPAHVVNPEVLGS Sbjct 181 EARQARMVADDLGALLSGNRPAHVVNPEVLGS 212 >gi|289749235|ref|ZP_06508613.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis T92] gi|289689822|gb|EFD57251.1| D-3-phosphoglycerate dehydrogenase serA2 [Mycobacterium tuberculosis T92] Length=174 Score = 327 bits (839), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 170/171 (99%), Positives = 170/171 (99%), Gaps = 0/171 (0%) Query 1 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 60 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV Sbjct 4 VTPRPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVV 63 Query 61 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA Sbjct 64 ESDSVGGPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 123 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVR 171 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRA R Sbjct 124 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAQR 174 >gi|240168710|ref|ZP_04747369.1| autoinducer-2 (AI-2) kinase [Mycobacterium kansasii ATCC 12478] Length=1286 Score = 233 bits (593), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 154/338 (46%), Positives = 198/338 (59%), Gaps = 20/338 (5%) Query 4 RPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESD 63 RPR LVTA + G A LR L D Y + + +R+ + L + + V V + E D Sbjct 531 RPRILVTADMDDDGLAALRALGDAEYASF--RTAMRLLTGPSLVEALAGV--QVFITEVD 586 Query 64 SVGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAV 121 V + LRVVAA RG+ NVD+ TA GIPVL+ P RNADAVA++TVA LL + Sbjct 587 VVDADAIRQLPELRVVAACRGNAVNVDLAACTAFGIPVLYAPGRNADAVADLTVAFLLML 646 Query 122 ARHLIPADA-----DVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSG 176 AR L A A + +G++ R G + +G E+ T GLVG GAVGRAV RL Sbjct 647 ARRLPTASAFLHQPGIAAGDMGRMGQA-FAGLQGRELWHKTIGLVGFGAVGRAVTRRLRA 705 Query 177 LGLRVIAHDPYRD-------DAG-HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMR 228 G RV+ DPY D DA SLDELL ++ VS+HAAV++ + GMIGA A MR Sbjct 706 FGARVLVFDPYVDAEQIVLADAEPASLDELLENSEFVSLHAAVSEQSRGMIGAAALARMR 765 Query 229 DGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIG 288 G+ +NTAR+ L D AL DALR G L A LD F+ E +DHPL+++ NV+ TPH+G Sbjct 766 PGSCLVNTARAALVDEAALADALRSGHLGGAALDVFSVEPPGSDHPLLALDNVIATPHVG 825 Query 289 GATWNTEARQARMVADDLGALLSGNRPAHVVNPEVLGS 326 G T + A Q R++A DL LL G P HV+NPE L S Sbjct 826 GNTIDVAAHQGRIIAADLRRLLVGEAPLHVLNPETLHS 863 >gi|302338895|ref|YP_003804101.1| D-isomer specific 2-hydroxyacid dehydrogenase [Spirochaeta smaragdinae DSM 11293] gi|301636080|gb|ADK81507.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Spirochaeta smaragdinae DSM 11293] Length=330 Score = 203 bits (517), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 119/333 (36%), Positives = 185/333 (56%), Gaps = 17/333 (5%) Query 6 RALVTAPLRGPGFAQLRR-LADVVYDPWID--QRPLRIYSAEQLADRITAVAADVLVVES 62 + LV AP+ +L ++VVY PW + +R Y + + + + DVL+ E Sbjct 2 KLLVRAPMTPNRIEELENYFSEVVYLPWTETGER----YYEDAMLESLKKYEPDVLITEL 57 Query 63 DSVGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 D + V + L+ + R +P+N+D+ TAAGIPVL TPARN AVAEM V L+L Sbjct 58 DRITKKVLDNYHNLQAIGDCRANPANIDVDACTAAGIPVLCTPARNCQAVAEMVVGLVLT 117 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 + R++IPA V+ + +GT PY + G E+ G G VG GAVG+A G Sbjct 118 LYRNIIPATQWVKEMK-WVEGTTPYYLWMGHELQGKNIGFVGFGAVGKATAHLFEAFGCE 176 Query 181 VIAHDPYRDDAGH-----SLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLN 235 + +DPY + S++E+ +E DIVS+H V D T GMI + F+ M+ ++F+N Sbjct 177 ISFYDPYVEAVSSSYRKCSVEEIFSENDIVSIHLPVLDSTRGMINKKLFSLMKPDSLFVN 236 Query 236 TARSQLRDTDALVDALRGGKLAAAGLDHFTGE-WLPTDHPLVSMPNVVLTPHIGGATWNT 294 +ARS + D ++L +AL+ +++ A LD E P D ++S PNV+LTPHI GA++ Sbjct 237 SARSAVVDYESLCEALKEKQISGAILDVLDTEPPKPEDLEILSYPNVLLTPHICGASYEV 296 Query 295 EARQARMVADDLGALLSG-NRPAHVVNPEVLGS 326 + Q+ ++ +++ L G N + V N VL S Sbjct 297 TSHQSDIITNNVIQWLEGRNLESVVYNKHVLKS 329 >gi|309777701|ref|ZP_07672651.1| D-3-phosphoglycerate dehydrogenase [Erysipelotrichaceae bacterium 3_1_53] gi|308914605|gb|EFP60395.1| D-3-phosphoglycerate dehydrogenase [Erysipelotrichaceae bacterium 3_1_53] Length=329 Score = 202 bits (515), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 119/321 (38%), Positives = 176/321 (55%), Gaps = 10/321 (3%) Query 6 RALVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 + V AP+ +L+ L +VVYDPW ++ R Y E LA + V D+L+ E D Sbjct 2 KVYVRAPMSEIRLQELKELFEEVVYDPW-NKTGERYYEKEMLA-ALKKVQPDILITELDR 59 Query 65 VGGPVFE--RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 + V GL+V+ R +P+N+D+ +A GIPVL TPARNA AVAEM V +L+A Sbjct 60 ITEAVLSGYEGLKVIGDCRANPANIDVAACSAHGIPVLCTPARNATAVAEMLVGMLIAYM 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R+L+PA A ++ G +++GT PY + G E+ G G VG GAVG+A L G + Sbjct 120 RNLLPATAWIKDGQ-WKEGTTPYYTWMGNELHGKHVGFVGFGAVGKAAAHLLDAFGCSIR 178 Query 183 AHDPYRDDAGHS---LDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 +DPY D ++ L EL A DI+S+H V +T +I + M+ A+F+NTARS Sbjct 179 FYDPYVKDTPYTKCELQELFATCDIISIHLPVLPETEKLISRELLYTMKQDAIFVNTARS 238 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGE-WLPTDHPLVSMPNVVLTPHIGGATWNTEARQ 298 + D +AL D + ++ LD E LP D ++ NV+LTPHI GAT+ Q Sbjct 239 AVVDMEALQDMAKEKRIKGILLDVLASEPPLPDDLSIIENDNVLLTPHICGATYEVTDHQ 298 Query 299 ARMVADDLGALLSGNRPAHVV 319 + ++ + L A + +V Sbjct 299 SDIITERLKAWKKQEQLERIV 319 >gi|313901317|ref|ZP_07834804.1| 4-phosphoerythronate dehydrogenase [Clostridium sp. HGF2] gi|312953925|gb|EFR35606.1| 4-phosphoerythronate dehydrogenase [Clostridium sp. HGF2] Length=329 Score = 199 bits (506), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 121/310 (40%), Positives = 170/310 (55%), Gaps = 10/310 (3%) Query 6 RALVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 + V AP+ +L+ L +VVYDPW ++ R Y E L + + V D+L+ E D Sbjct 2 KVYVRAPMSEIRLRELQELFEEVVYDPW-NKTGERFYEKEML-EALKTVQPDILITELDR 59 Query 65 VGGPVFE--RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 + V +GL+V+ R +P+N+DI +A GIPVL TPARNA AVAEM V +L+A Sbjct 60 ITEAVVSNYKGLKVIGDCRANPANIDIEACSAHGIPVLCTPARNATAVAEMLVGMLIAYM 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R L+PA A VR G + +GT PY + G E+ G G VG GAVG+A L G + Sbjct 120 RKLLPATAWVRDGQ-WIEGTTPYYTWMGNELHGKHVGFVGFGAVGKAAAHLLDAFGCSIS 178 Query 183 AHDPYRDDAGHS---LDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 +DPY D ++ L EL A D++S+H V T +I M+ AVF+NTARS Sbjct 179 YYDPYVSDTPYTKCELQELFAACDVISIHLPVLPATEKLISRDLLYTMKPDAVFVNTARS 238 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGE-WLPTDHPLVSMPNVVLTPHIGGATWNTEARQ 298 + D +AL D R ++ LD E LP D ++ NV+LTPHI GAT+ Q Sbjct 239 AVVDMEALQDMAREKRIKGILLDVLNSEPPLPDDLKIIENDNVLLTPHICGATYEVTDHQ 298 Query 299 ARMVADDLGA 308 + ++ + L A Sbjct 299 SDIITERLKA 308 >gi|269839501|ref|YP_003324193.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] gi|269791231|gb|ACZ43371.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] Length=353 Score = 191 bits (484), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 117/279 (42%), Positives = 159/279 (57%), Gaps = 12/279 (4%) Query 56 DVLVVESDSVGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEM 113 +++V E + VF LR+V TRG P NV++ AT G+ V + P RNA A AE Sbjct 69 EIVVTEMAPLTARVFAAADSLRLVVVTRGGPVNVNLEAATRHGVVVCNIPGRNAQAAAEY 128 Query 114 TVALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWR 173 + ++LA R + A + + G +R Y+ G E+ G T GLVG GA+GR V Sbjct 129 ALGMILAAVRRIAEAHSSLVGGR-WRGDLYAYEEA-GFELGGSTVGLVGFGAIGRIVARA 186 Query 174 LSGLGLRVIAHDPYRDD--------AGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFA 225 L+ LG +V+ HDPY D A SL+ELL + +VS+HA +T +T G+IG + Sbjct 187 LTALGAQVLVHDPYVTDEEVRAVGAARTSLEELLRSSRVVSLHARLTSETAGLIGRHEIQ 246 Query 226 AMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTP 285 M G+ +NTAR L D AL++AL G L AA LD F E LP D PL++MP VV++P Sbjct 247 LMPRGSALVNTARGGLLDYSALIEALESGHLWAAALDVFPEEPLPPDSPLLTMPRVVVSP 306 Query 286 HIGGATWNTEARQARMVADDLGALLSGNRPAHVVNPEVL 324 HI GAT T R AR+ A +G L G HV+NPEV+ Sbjct 307 HIAGATRETAKRAARLAAVQVGRYLRGETLQHVLNPEVM 345 >gi|119719732|ref|YP_920227.1| glyoxylate reductase [Thermofilum pendens Hrk 5] gi|205781929|sp|A1RYE4.1|GYAR_THEPD RecName: Full=Glyoxylate reductase gi|119524852|gb|ABL78224.1| Glyoxylate reductase [Thermofilum pendens Hrk 5] Length=339 Score = 190 bits (483), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 127/332 (39%), Positives = 175/332 (53%), Gaps = 18/332 (5%) Query 4 RPRALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESD 63 RP+ VT + PG + L+ DVV D P S E+L I A +L + +D Sbjct 3 RPKVYVTRIIPEPGLSMLKECCDVVVHESKDWPP----SREELLRNIRDKDA-LLCLLTD 57 Query 64 SVGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAV 121 + V + L+V++ ++DIP AT GI V HTP DAVAE TV L+LAV Sbjct 58 KIDAEVMDAAPNLKVISTYSVGFDHIDIPEATKRGIYVTHTPGVLTDAVAEFTVGLILAV 117 Query 122 ARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRV 181 R ++ AD +R+G + PY G E+ G T GLVGLG +G A RLS +++ Sbjct 118 TRRIVEADKIIRTGQWDKPWN-PY-FLTGPELKGKTIGLVGLGRIGVATAKRLSSFDVKI 175 Query 182 IAHDPYR---------DDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAV 232 + +D R + LD LL ++DIVS+H +T +T +I ++ M+ A Sbjct 176 LYYDIERRWDVETVIPNMEFTDLDTLLEKSDIVSIHVPLTKETYHLINEERLRKMKKTAY 235 Query 233 FLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATW 292 +NTAR + DT+ALV AL+ G +A A LD F E LP +HPL NVVL PHI AT Sbjct 236 LINTARGPVVDTEALVKALKEGWIAGAALDVFEQEPLPPNHPLTKFDNVVLAPHIASATI 295 Query 293 NTEARQARMVADDLGALLSGNRPAHVVNPEVL 324 R A + A +L A+L G P +VN EVL Sbjct 296 EARQRMAELAARNLIAVLKGEMPPALVNKEVL 327 >gi|332798442|ref|YP_004459941.1| phosphoglycerate dehydrogenase [Tepidanaerobacter sp. Re1] gi|332696177|gb|AEE90634.1| Phosphoglycerate dehydrogenase [Tepidanaerobacter sp. Re1] Length=343 Score = 188 bits (478), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 107/338 (32%), Positives = 173/338 (52%), Gaps = 34/338 (10%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSV 65 +ALVTA + +L L D+ Y+ W ++ R+ + E++ + D+++ D + Sbjct 2 KALVTAEVNSDIIKELENLIDITYEGW--EKEYRVLTEEEMISY--SRDKDIIITSYDPI 57 Query 66 GGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 V + L+++ TR +P N+DI A I + + P RN+D AE TVAL+LAV R Sbjct 58 TKEVIGQCPNLKLIVCTRSNPVNIDIKYAREKNIKISYAPGRNSDCTAEFTVALMLAVTR 117 Query 124 HLIPADADVRSGN--------------IFRDGT------IPYQRFRGAEIAGLTAGLVGL 163 + A ++ G + RD T PY F+G ++ G T G++G Sbjct 118 KIPMAYKALKDGKHVGLKEKQQTIKAGLRRDVTWDLNDKSPYVMFKGTQLKGKTVGIIGY 177 Query 164 GAVGRAVRWRLSGLGLRVIAHDPYRDDAGH-------SLDELLAEADIVSMHAAVTDDTI 216 G++GR V G+ V+ +DP+ + S DELL +ADIVS+H ++T Sbjct 178 GSIGRRVANICRAFGMNVLINDPFFKNTDEITGVTFVSFDELLKQADIVSVHCKDCEETQ 237 Query 217 GMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLV 276 +I A+ F M+ A +NT+R L D AL+DAL ++A A LD F+ E + DHP + Sbjct 238 NLINARAFELMKKTAFLINTSRGALVDEQALIDALASKRIAGAALDVFSSEPIAADHPFI 297 Query 277 S-MPNVVLTPHIGGATWNTEARQARMVADDLGALLSGN 313 + + NVV+TPH+ GAT++ + +D+ L G Sbjct 298 TELDNVVITPHLAGATYDAIDNHTHQLVEDVKLFLEGK 335 >gi|255533386|ref|YP_003093758.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Pedobacter heparinus DSM 2366] gi|255346370|gb|ACU05696.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Pedobacter heparinus DSM 2366] Length=319 Score = 188 bits (478), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 114/320 (36%), Positives = 171/320 (54%), Gaps = 15/320 (4%) Query 6 RALVTAPLRGPGFAQL-RRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 R L+TAP G L +L +VVY PW D R + ++L + + AD L+ E D Sbjct 2 RILITAPYNEQGQQTLAEKLGEVVYRPWKDLG--RAFHEDELIELLAETKADALITEHDH 59 Query 65 VGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V V L+ + RG PSNV + A A GIPV HTPARNA AVAEM +A ++ + Sbjct 60 VTAKVITANPHLQFIGVCRGTPSNVSLETAKAMGIPVFHTPARNAQAVAEMFLATVIDLM 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R+ A ++ N D Y +F+G E+AG T G+VG GAVG+ + + + Sbjct 120 RNTYAGVAWLKDRNWTADAHTSYLQFKGNEMAGKTIGMVGFGAVGQRIASMVENFPCSIK 179 Query 183 AHDPYRDD-----AGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTA 237 +DPY ++ SL+++ A +DIVS+H V + TIGMI + MR A+F+NTA Sbjct 180 FYDPYLENFDARYTKTSLEDVFASSDIVSIHLPVNEATIGMIDKSLISKMRPDAIFVNTA 239 Query 238 RSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWNT 294 R+ + D L++AL ++ A LD F E P D+ ++++PNV+ TPHI GAT Sbjct 240 RASVVKRDDLLEALENKRIRGAVLDVFDHE--PPDEKDYRIINLPNVLATPHIAGATHEV 297 Query 295 EARQARMVADDLGALLSGNR 314 E ++ + + + + Sbjct 298 EDHHVEIMNNRIMTWFAQEK 317 >gi|167759501|ref|ZP_02431628.1| hypothetical protein CLOSCI_01849 [Clostridium scindens ATCC 35704] gi|336420997|ref|ZP_08601158.1| hypothetical protein HMPREF0993_00535 [Lachnospiraceae bacterium 5_1_57FAA] gi|167663058|gb|EDS07188.1| hypothetical protein CLOSCI_01849 [Clostridium scindens ATCC 35704] gi|336004016|gb|EGN34092.1| hypothetical protein HMPREF0993_00535 [Lachnospiraceae bacterium 5_1_57FAA] Length=316 Score = 188 bits (477), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 118/319 (37%), Positives = 169/319 (53%), Gaps = 14/319 (4%) Query 6 RALVTAPLRGPGFAQLRRLAD-VVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 + L+ AP +L D +VY PW R Y E L + + D L+ E D Sbjct 2 KLLIRAPFIESERKRLEAYFDEIVYAPWTTTGE-RYYEDEML-EVLKKEQPDALITELDR 59 Query 65 VGGPVFE--RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V V L + R +P+N+D+ A +PVL TPARNA AVAEM LL++ Sbjct 60 VTEKVLNGYDKLIFIGDCRANPANIDVEACKKANVPVLCTPARNAQAVAEMLSGLLVSYM 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R+L+PA ++ G + +GT PY + G E+ G G VG GAVG+ L G + Sbjct 120 RNLVPAVQWIKDGK-WVEGTTPYYTWMGNELCGKKVGFVGFGAVGKHAAKILEAYGCEIS 178 Query 183 AHDPYRDDAGHS-----LDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTA 237 +DP+ D S L+E+ +DIVS+H V D T GMI A+ FA M++ A+F+NTA Sbjct 179 FYDPFVDFVKDSYKKCELEEIFENSDIVSIHLPVLDSTKGMINAELFARMKETAIFVNTA 238 Query 238 RSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPL--VSMPNVVLTPHIGGATWNTE 295 RS + D AL++AL+ K+ A LD E PT+ L + NV+LTPHI GAT+ Sbjct 239 RSAVVDKPALMEALKTKKIRGAILDVLEVE-PPTEEALEIARLDNVLLTPHICGATYEVT 297 Query 296 ARQARMVADDLGALLSGNR 314 Q+R++ D + A + N+ Sbjct 298 DHQSRIMTDRIDAWMKENK 316 >gi|154686308|ref|YP_001421469.1| YoaD [Bacillus amyloliquefaciens FZB42] gi|154352159|gb|ABS74238.1| YoaD [Bacillus amyloliquefaciens FZB42] Length=338 Score = 188 bits (477), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 112/314 (36%), Positives = 173/314 (56%), Gaps = 23/314 (7%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 L+TAP G +L L V+ PW ++ R Y ++L I A L+ E D V Sbjct 4 LITAPYHDEGLKELTELFGRTVHRPW--KKHGRAYREDELIRMIQETNASGLITELDEVS 61 Query 67 GPVFERGLRV------VAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ER + + + RG PSNVDI AT IPV TPARNA AVAEM + +++ Sbjct 62 ----ERVIDILPDSAFIGVCRGMPSNVDIAAATKRKIPVFFTPARNAQAVAEMFIGNVIS 117 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RH + ++ G D Y +FRG E+ G T GL+G GAVG+ + L+ + Sbjct 118 FLRHTYSSHQWLKDGKWNGDYLQAYVKFRGNELTGKTVGLIGFGAVGQRIARLLAAFDCK 177 Query 181 VIAHDPY-----RDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLN 235 V+ +DP+ R+ +++ + +E+DIVS+H T++TIG+IGA+ F M+ AVF+N Sbjct 178 VLYYDPFVRHENREYEKTTIERVFSESDIVSVHLPRTEETIGLIGARHFQLMKQEAVFVN 237 Query 236 TARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATW 292 T+R+ + D + L+ L+ ++ A LD F E P +D+ L+S+PNV+ TPH+ GAT+ Sbjct 238 TSRAAVTDREELLRVLKERRIKGAILDVFYHE--PPESSDYELISLPNVLATPHLAGATF 295 Query 293 NTEARQARMVADDL 306 E +++ + L Sbjct 296 EVEDHHVKILNEAL 309 >gi|305662806|ref|YP_003859094.1| Glyoxylate reductase [Ignisphaera aggregans DSM 17230] gi|304377375|gb|ADM27214.1| Glyoxylate reductase [Ignisphaera aggregans DSM 17230] Length=338 Score = 187 bits (474), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 110/263 (42%), Positives = 153/263 (59%), Gaps = 11/263 (4%) Query 72 RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADAD 131 + LR+VA N+D+ AT GI V +TP +A AE+T AL+L+VAR ++ AD Sbjct 67 KNLRIVAQLAVGYDNIDVECATRLGIYVTNTPGVLTEATAELTWALILSVARRIVEADHY 126 Query 132 VRSGNIFRDGT--IPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRD 189 VR G +R T P G E+ G T G++GLG +GR V G++++ +D RD Sbjct 127 VRWGEWYRTKTGWHPLMML-GVELKGKTLGIIGLGRIGRRVAEIGKAFGMKIMYYDRSRD 185 Query 190 DAGH--------SLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQL 241 + SLDE+L+E+DIVS+H +T +T MI ++ M+ A+ +NTAR + Sbjct 186 EEAEKILGAEYRSLDEVLSESDIVSIHVPLTKETYHMINEEKLKRMKRTALLINTARGAV 245 Query 242 RDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNTEARQARM 301 DTDALV AL+ G +A AGLD F E LP +HPL + NVVL PHIG AT T A + Sbjct 246 IDTDALVKALKEGWIAGAGLDVFEEEPLPPNHPLTAFKNVVLLPHIGSATIETRHAMAEL 305 Query 302 VADDLGALLSGNRPAHVVNPEVL 324 VA++L A G P +VN EV+ Sbjct 306 VAENLIAFYQGREPPTLVNKEVV 328 >gi|332296720|ref|YP_004438642.1| Phosphoglycerate dehydrogenase [Treponema brennaborense DSM 12168] gi|332179823|gb|AEE15511.1| Phosphoglycerate dehydrogenase [Treponema brennaborense DSM 12168] Length=347 Score = 186 bits (472), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 110/333 (34%), Positives = 176/333 (53%), Gaps = 36/333 (10%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSV 65 + TA L A++++D W R L + QLA++ A AD++V D + Sbjct 5 KIFFTAEYDANELEPLAEFAEILFDGW--ARGLPKLTEAQLAEK--AADADMIVTSYDDI 60 Query 66 GGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 V E L+++A TR P N+D+ A IPVL TP RN+D+ AE+TVAL+L AR Sbjct 61 TREVIEHAPHLKLIACTRATPVNIDVQAAREKNIPVLFTPGRNSDSAAELTVALMLCAAR 120 Query 124 HLIPADADVRSG------------------NIFRDGTI--PYQRFRGAEIAGLTAGLVGL 163 H+ A + ++ G ++ D T+ PY F+G ++ G T G++G Sbjct 121 HVPQAHSALKKGLFTAPETVPNQAKAGLKQDVIWDMTVDAPYTVFKGTQLKGKTLGILGY 180 Query 164 GAVGRAVRWRLSGLGLRVIAHDPYRDDAG---------HSLDELLAEADIVSMHAAVTDD 214 G++GR V +G++++ +DPY+ + SL++L+ E+D ++ H VT + Sbjct 181 GSIGRRVGKIARAMGMQLLVYDPYQSEIEIEEIGIMKVRSLEQLMRESDFITCHMKVTPE 240 Query 215 TIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHP 274 T GMI ++ A M+ A F+NT+R + D A++DALR K+A A D + E L +HP Sbjct 241 TRGMINRERIALMKPSAYFINTSRGSVLDESAMIDALRRKKIAGAAFDVYEHEPLARNHP 300 Query 275 LVS-MPNVVLTPHIGGATWNTEARQARMVADDL 306 ++ + NVV+TPHI GAT R + D+ Sbjct 301 YITELDNVVVTPHIAGATREVLTNHTRQIVSDI 333 >gi|16078917|ref|NP_389738.1| 2-hydroxyacid dehydrogenase [Bacillus subtilis subsp. subtilis str. 168] gi|221309747|ref|ZP_03591594.1| hypothetical protein Bsubs1_10221 [Bacillus subtilis subsp. subtilis str. 168] gi|221314069|ref|ZP_03595874.1| hypothetical protein BsubsN3_10152 [Bacillus subtilis subsp. subtilis str. NCIB 3610] gi|221318990|ref|ZP_03600284.1| hypothetical protein BsubsJ_10073 [Bacillus subtilis subsp. subtilis str. JH642] gi|221323264|ref|ZP_03604558.1| hypothetical protein BsubsS_10192 [Bacillus subtilis subsp. subtilis str. SMY] gi|81815790|sp|O34815.1|YOAD_BACSU RecName: Full=Putative 2-hydroxyacid dehydrogenase yoaD gi|2619022|gb|AAB84446.1| YoaD [Bacillus subtilis] gi|2634250|emb|CAB13749.1| putative 2-hydroxyacid dehydrogenase [Bacillus subtilis subsp. subtilis str. 168] Length=344 Score = 186 bits (472), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 109/299 (37%), Positives = 166/299 (56%), Gaps = 15/299 (5%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 LVTAP G +L L V Y W +Q R Y ++L + A A L+ E D V Sbjct 15 LVTAPYNEEGRKELENLFGSVAYQSWKEQG--RAYREDELIQLLKATNATGLITELDQVT 72 Query 67 GPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARH 124 VF L V RG PSNVD+ A+ GIPV +TP RNA AVAEM + +++ RH Sbjct 73 DSVFASVPELSFVGVCRGMPSNVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRH 132 Query 125 LIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAH 184 ++ ++ G D Y +F+G E+ G T G++G GAVG+ + L+ ++ + Sbjct 133 TSASNQWLKDGEWDSDYLQAYVKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYY 192 Query 185 DPYRDD-----AGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 DPY D SL + +++DIVS+H T++T+G+I Q F M++ A+F+NT+R+ Sbjct 193 DPYIQDDHPLYEKASLKTVFSDSDIVSVHLPRTEETLGLIDRQYFDLMKESAIFVNTSRA 252 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWNTE 295 + + + L+ L+ K++ A LD F E P +D+ L+S+PNV+ TPH+ GAT+ E Sbjct 253 VVVNREDLLFVLKEHKISGAILDVFYHE--PPEESDYELISLPNVLATPHLAGATFEVE 309 >gi|328553215|gb|AEB23707.1| YoaD [Bacillus amyloliquefaciens TA208] gi|341827449|gb|AEK88700.1| putative 2-hydroxyacid dehydrogenase [Bacillus amyloliquefaciens XH7] Length=333 Score = 184 bits (467), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 110/314 (36%), Positives = 172/314 (55%), Gaps = 23/314 (7%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 L+TAP G +L L V+ PW ++ R Y ++L I A L+ E D V Sbjct 4 LITAPYHDEGLKELTELFGRTVHRPW--KKHGRAYREDELIRMIQETNAAGLITELDEVS 61 Query 67 GPVFERGLRV------VAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ER + + + RG PSNVDI AT IPV TPARNA AVAE+ + +++ Sbjct 62 ----ERVIDILPDSAFIGVCRGMPSNVDIEAATKRKIPVFFTPARNAQAVAELFIGNVIS 117 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RH + ++ G D Y +FRG E+ G T GL+G GAVG+ + L+ + Sbjct 118 FLRHTYSSHQWLKDGKWNGDYLQAYVKFRGNELTGKTVGLIGFGAVGQRIARLLAAFDCK 177 Query 181 VIAHDPY-----RDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLN 235 V+ +DP+ R+ +++ + +E+DIVS+H T++TIG+IGA+ F M+ AVF+N Sbjct 178 VLYYDPFVNHENREYEKTTMERVFSESDIVSVHLPRTEETIGLIGAKHFQLMKQEAVFVN 237 Query 236 TARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATW 292 T+R+ + D + L+ L+ ++ A LD F E P +D+ ++S+PNV+ TPH+ GA + Sbjct 238 TSRAAVTDREELLRVLKERRIKGAILDVFYHE--PPESSDYEIISLPNVLATPHLAGAPF 295 Query 293 NTEARQARMVADDL 306 E R++ + L Sbjct 296 EVEDHHVRILNEAL 309 >gi|311068575|ref|YP_003973498.1| putative 2-hydroxyacid dehydrogenase [Bacillus atrophaeus 1942] gi|310869092|gb|ADP32567.1| putative 2-hydroxyacid dehydrogenase [Bacillus atrophaeus 1942] Length=333 Score = 183 bits (465), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 112/299 (38%), Positives = 167/299 (56%), Gaps = 15/299 (5%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 L+TAP G +L L VVY W + R + ++L I A L+ E D V Sbjct 4 LITAPYNERGRKELEGLFGAVVYQSWKGRG--RAFREDELIQLIKNTDATGLIAELDQVT 61 Query 67 GPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARH 124 V + L V RG PSNVDI AT GIPV +TPARNA AVAEM + ++ RH Sbjct 62 EHVLQSSPELAFVGVCRGMPSNVDIKAATKRGIPVFYTPARNAQAVAEMFIGNIITFLRH 121 Query 125 LIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAH 184 +P++ ++ G RD Y +F+G EI G T G+VG GAVG+ + L+ +V + Sbjct 122 TMPSNQWLKDGKWNRDYLQAYVQFKGNEITGKTVGMVGFGAVGQRIAKLLTAFDCKVKYY 181 Query 185 DPY--RDDAGH---SLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 DP+ D+ + +L+ + +++DIVS+H T++T G+I F M+ AVF+NT+R+ Sbjct 182 DPFVTHDNPQYEKVALENIFSDSDIVSVHLPRTEETAGLISQAYFDLMKKDAVFVNTSRA 241 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWNTE 295 + + + L+ L+ K+ A LD F E P +D+ L+S+PNV+ TPH+ GAT+ E Sbjct 242 VVVNREDLLAVLKQNKIRGAILDVFYNE--PPESSDYELISLPNVLATPHLAGATYEVE 298 >gi|170750794|ref|YP_001757054.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium radiotolerans JCM 2831] gi|170657316|gb|ACB26371.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium radiotolerans JCM 2831] Length=326 Score = 183 bits (465), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 132/330 (40%), Positives = 177/330 (54%), Gaps = 29/330 (8%) Query 7 ALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 L+ P+ G +LR ++ RP +E LA + AD + V + + G Sbjct 6 CLIVQPIHAAGLDRLR-------AAGLEPRPASGTDSETLAREV----ADCVAVITRNTG 54 Query 67 ----GPVFERGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 LRV+ +V ATAAGI V++TP NA +VAE T+AL+ A+A Sbjct 55 FPARAIAAAPALRVIGVHGTGTDHVATAEATAAGIVVVNTPGANAVSVAEQTLALIFALA 114 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 + L AD VR+G D + + R E+AGLT GLVG GA+G+A + LGLRV+ Sbjct 115 KALPEADRSVRTG----DDSFKFTA-RLIELAGLTLGLVGFGAIGQATARLAAALGLRVL 169 Query 183 AHDPYRDDA---------GHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVF 233 A+ P R DA S+D LLAEADIVS+H +T T G+IG Q A M+ A Sbjct 170 AYGPSRPDADFANAGALRAASVDALLAEADIVSLHVPLTPGTRGLIGRDQLARMKREAFL 229 Query 234 LNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWN 293 +NT+R L D ALV+AL G +A AGLD F E LP DHPL P +LTPH+GG+T Sbjct 230 INTSRGGLIDEAALVEALEAGTIAGAGLDVFAQEPLPVDHPLARQPRAILTPHVGGSTGA 289 Query 294 TEARQARMVADDLGALLSGNRPAHVVNPEV 323 R A A + +L+G RP +VNP+V Sbjct 290 ALIRTAETAATRVVDVLAGRRPGGLVNPDV 319 >gi|328912008|gb|AEB63604.1| D-3-phosphoglycerate dehydrogenase [Bacillus amyloliquefaciens LL3] Length=333 Score = 182 bits (463), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 109/314 (35%), Positives = 172/314 (55%), Gaps = 23/314 (7%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 ++TAP G +L L V+ PW ++ R Y ++L I A L+ E D V Sbjct 4 VITAPYHDEGLKELTELFGRTVHRPW--KKHGRAYREDELIRMIQETNAAGLITELDEVS 61 Query 67 GPVFERGLRV------VAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLA 120 ER + + + RG PSNVDI AT IPV TPARNA AVAE+ + +++ Sbjct 62 ----ERVIDILPDSAFIGVCRGMPSNVDIEAATKRKIPVFFTPARNAQAVAELFIGNVIS 117 Query 121 VARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLR 180 RH + ++ G D Y +FRG E+ G T GL+G GAVG+ + L+ + Sbjct 118 FLRHTYSSHQWLKDGKWNGDYLQAYVKFRGNELTGKTVGLIGFGAVGQRIARLLAAFDCK 177 Query 181 VIAHDPY-----RDDAGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLN 235 V+ +DP+ R+ +++ + +E+DIVS+H T++TIG+IGA+ F M+ AVF+N Sbjct 178 VLYYDPFVNHENREYEKTTMERVFSESDIVSVHLPRTEETIGLIGAKHFQLMKQEAVFVN 237 Query 236 TARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATW 292 T+R+ + D + L+ L+ ++ A LD F E P +D+ ++S+PNV+ TPH+ GA + Sbjct 238 TSRAAVTDREELLRVLKERRIKGAILDVFYHE--PPESSDYEIISLPNVLATPHLAGAPF 295 Query 293 NTEARQARMVADDL 306 E R++ + L Sbjct 296 EVEDHHVRILNEAL 309 >gi|321311502|ref|YP_004203789.1| putative 2-hydroxyacid dehydrogenase [Bacillus subtilis BSn5] gi|320017776|gb|ADV92762.1| putative 2-hydroxyacid dehydrogenase [Bacillus subtilis BSn5] Length=344 Score = 181 bits (460), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 107/299 (36%), Positives = 163/299 (55%), Gaps = 15/299 (5%) Query 8 LVTAPLRGPGFAQLRRL-ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 LVTAP G +L L V Y W +Q R Y ++L + A A L+ E D V Sbjct 15 LVTAPYNEEGRKELENLFGSVTYQSWKEQG--RAYREDELIQLLKATNATGLITELDQVT 72 Query 67 GPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARH 124 VF L V RG PSNVD+ A+ GIPV + P RNA AVAEM + +++ RH Sbjct 73 DSVFASVPELSFVGVCRGMPSNVDVAAASKRGIPVFYAPGRNAQAVAEMFIGNVISFLRH 132 Query 125 LIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAH 184 ++ ++ G D Y +F+G E+ G T G++G GAVG+ + L+ ++ + Sbjct 133 TSASNQWLKDGKWNSDYLQAYVKFKGNELTGKTVGMIGFGAVGQRIAKLLTVFDCKIKYY 192 Query 185 DPYRDD-----AGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARS 239 DPY D SL + +++DIVS+H T++T+G+I + F M+ A+F+NT+R+ Sbjct 193 DPYIQDDHPLYEKVSLKTVFSDSDIVSVHLPRTEETLGLIDRKHFDLMKQSAIFVNTSRA 252 Query 240 QLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWNTE 295 + + + L+ L+ K+ A LD F E P +D+ L+S+PNV+ TPH+ GAT+ E Sbjct 253 VVVNREDLLSVLKEHKIRGAILDVFYHE--PPEESDYELISLPNVLATPHLAGATFEVE 309 >gi|289523731|ref|ZP_06440585.1| D-3-phosphoglycerate dehydrogenase [Anaerobaculum hydrogeniformans ATCC BAA-1850] gi|289503423|gb|EFD24587.1| D-3-phosphoglycerate dehydrogenase [Anaerobaculum hydrogeniformans ATCC BAA-1850] Length=342 Score = 180 bits (457), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 107/280 (39%), Positives = 154/280 (55%), Gaps = 12/280 (4%) Query 55 ADVLVVESDSVGGPVFE--RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAE 112 ADVLVV++ V + + L+ VA TRG P NV+I T+ IP+ ++P RN AV E Sbjct 64 ADVLVVDTAPVTEALLQAASKLKAVACTRGGPVNVNIKACTSMKIPLFNSPGRNESAVVE 123 Query 113 MTVALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRW 172 TV LA+ +++ +++ G I+R Y + G E++ LT G+VG G VGR V Sbjct 124 FTVGATLALMKNMALGHYELKRG-IWRGDLYLYDKV-GPELSDLTVGIVGYGKVGRNVAK 181 Query 173 RLSGLGLRVIAHDPYR-----DDAGH---SLDELLAEADIVSMHAAVTDDTIGMIGAQQF 224 S G +V+ +DPY ++ GH S +ELL AD+VS+H ++ +T M+ +F Sbjct 182 MFSLFGCQVLVYDPYVTPSIIEEEGHKSTSFEELLKTADVVSLHVRLSPETEKMMDGSKF 241 Query 225 AAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLT 284 M+ + F+NTAR + D DAL +AL GK+ A LD F E LP DHPL + NV+LT Sbjct 242 NLMKSTSYFVNTARGGIVDYDALYEALAKGKIKGAALDVFDPEPLPPDHPLTKLDNVLLT 301 Query 285 PHIGGATWNTEARQARMVADDLGALLSGNRPAHVVNPEVL 324 PHI GA+ + R VA L + VN E+ Sbjct 302 PHIAGASQKSAIRGIETVAGSLYLYFDKGELKNCVNKEIF 341 >gi|302347920|ref|YP_003815558.1| Glyoxylate reductase [Acidilobus saccharovorans 345-15] gi|302328332|gb|ADL18527.1| Glyoxylate reductase [Acidilobus saccharovorans 345-15] Length=335 Score = 178 bits (452), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 124/330 (38%), Positives = 176/330 (54%), Gaps = 16/330 (4%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSV 65 R VT + P F ++ L V D W + RP + E+L R A V ++E D V Sbjct 4 RLFVTREIPFPAFESIKGLFQKV-DVWPEYRPP---TKEELISRAKGAQALVTMLE-DKV 58 Query 66 GGPVFER---GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V E LR++A N+D+ AT G+ V +TP DA A++T AL+LAVA Sbjct 59 TCDVIEALSPELRIIAQYAVGFDNIDLECATKHGVYVTNTPDVLTDATADLTWALILAVA 118 Query 123 RHLIPADADVRSGNIFRDGTIPY-QRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRV 181 R ++ +DA VRSG GT + G ++ G T G+VG G +G+AV R G +R+ Sbjct 119 RRIVESDAYVRSGGWKSSGTAWHPTMMLGFDLVGKTLGIVGGGRIGQAVARRAKGFDMRI 178 Query 182 IAHDPYRDDAGHSL-------DELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFL 234 I + R +L DEL E+DIV++H +T +T ++ + M+ A+ + Sbjct 179 IYNSRRRHPEMEALGATYVDLDELFRESDIVTLHVPLTPETQNLVNESRLRLMKRTAIVV 238 Query 235 NTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNT 294 NTAR ++ D DAL AL+ G +A AGLD + E L HP+ + NVVLTPHIG AT T Sbjct 239 NTARGKVVDIDALYRALKEGWIAGAGLDVYPTEPLDPSHPITKLSNVVLTPHIGSATRET 298 Query 295 EARQARMVADDLGALLSGNRPAHVVNPEVL 324 A+ A +V +L A G RP +VN EVL Sbjct 299 RAKMAELVYRNLEAFSRGERPPTLVNEEVL 328 >gi|312129155|ref|YP_003996495.1| d-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein [Leadbetterella byssophila DSM 17132] gi|311905701|gb|ADQ16142.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Leadbetterella byssophila DSM 17132] Length=333 Score = 178 bits (452), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 111/318 (35%), Positives = 171/318 (54%), Gaps = 16/318 (5%) Query 6 RALVTAPLRGPGFAQL-RRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 + LVT+P G +L + + + VY PW D R ++ ++L + AD L+ E D Sbjct 2 KVLVTSPYNEGGLKELNQHVGETVYRPWKDNG--RAFNEDELIQLLKESEADALITEHDH 59 Query 65 VGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V V + L+ + RG PSNV I A+A IPV +TPARNA AVAE+ VA ++ Sbjct 60 VTEKVIQSFPDLKFIGVCRGTPSNVSIKEASAHRIPVFYTPARNAQAVAELFVANVITFL 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R + A+ +++G Y F+G E+AG G VG GA+G+ + ++ + Sbjct 120 RDTLFANEWLKAGKWDEGAHTSYLIFKGNELAGKKVGFVGFGAIGQLIASMIASYPCEIS 179 Query 183 AHDPY--RDD----AGHSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNT 236 +DPY +D S++E+ A DIVS+H VT++T G+I + F+ M+ A+F+NT Sbjct 180 YYDPYVKAEDFPLYQKQSVEEVFANNDIVSVHLPVTEETKGLISRELFSVMKPDALFVNT 239 Query 237 ARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWN 293 AR+ + D +AL++ + K+ A LD F E P D+ L+ NV+ TPHI GAT Sbjct 240 ARAVVVDRNALLEVIEQKKIKGAILDVFDHE--PPDELDYRLIRAKNVLATPHIAGATHE 297 Query 294 TEARQARMVADDLGALLS 311 E R++ + L LS Sbjct 298 VEDHHVRIMNETLVNWLS 315 >gi|312137068|ref|YP_004004405.1| d-3-phosphoglycerate dehydrogenase [Methanothermus fervidus DSM 2088] gi|311224787|gb|ADP77643.1| D-3-phosphoglycerate dehydrogenase [Methanothermus fervidus DSM 2088] Length=526 Score = 178 bits (451), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 112/326 (35%), Positives = 172/326 (53%), Gaps = 28/326 (8%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS- 64 + LVT P+ G +L ++ADV + Q E+L D I A LVV S + Sbjct 3 KILVTDPINEKGIKELEKIADVTVKTDMSQ--------EELIDEIGKYNA--LVVRSGTK 52 Query 65 VGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V V E G L ++A N+D+ AT GI V++ P + VAE T+ L+L +A Sbjct 53 VTREVIEAGKNLEIIARAGVGVDNIDVGAATEKGIMVVNAPESTSITVAEHTMGLMLTLA 112 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R ++ AD VR G R +F G E+ G++GLG +G V R G++++ Sbjct 113 RKIVLADKSVRRGEWNR------SKFMGIELKDKVLGIIGLGRIGSQVSLRARAFGMKIL 166 Query 183 AHDPYRDDAGHS--------LDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFL 234 A+DPY D+ LDELL ++DIV++H +T +T +I ++ M++ A + Sbjct 167 AYDPYIDEESAESVGATLVELDELLKKSDIVTIHVPLTKETKHLISRRELKMMKNSAYII 226 Query 235 NTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGATWNT 294 N AR + D +AL++AL ++A A LD F E P+D PL+ NVVLTPHIG +T Sbjct 227 NCARGGIIDEEALIEALENNEIAGAALDVFEEEP-PSDSPLLEFDNVVLTPHIGASTVEA 285 Query 295 EARQARMVADDLGALLSGNRPAHVVN 320 + A +VA+++ + G P +V+N Sbjct 286 QRDAAIIVANEIKRIFDGKPPQNVIN 311 >gi|20808958|ref|NP_624129.1| D-3-phosphoglycerate dehydrogenase [Thermoanaerobacter tengcongensis MB4] gi|20517622|gb|AAM25733.1| Phosphoglycerate dehydrogenase and related dehydrogenases [Thermoanaerobacter tengcongensis MB4] Length=533 Score = 177 bits (450), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 111/331 (34%), Positives = 178/331 (54%), Gaps = 31/331 (9%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSV 65 + +VT + G L++ ADV I S E+L + I A ++V + V Sbjct 2 KIIVTEKISENGIDYLKKYADVDVKTNI--------SREELLEVIKDYDA-IIVRSATKV 52 Query 66 GGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 + E+G L+V+ N+D+ AT GI V++TPA N A AE+T+ L+LA+AR Sbjct 53 DRELIEKGEKLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIAR 112 Query 124 HLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIA 183 ++ A +G+ RD RF+G E+ G T G++GLG +G V RL+ +RVIA Sbjct 113 NIPQAYHAALNGDFRRD------RFKGVELNGKTVGIIGLGRIGSLVASRLAAFNMRVIA 166 Query 184 HDPYRDDAGH--------SLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLN 235 +DPY D +LDELL ++D +++H T++T MIG ++F M+ G +N Sbjct 167 YDPYMPDERFEKCGVKRVTLDELLEQSDFITIHIPKTEETKKMIGEKEFKKMKKGVRIVN 226 Query 236 TARSQLRDTDALVDALRGGKLAAAGLD------HFTGEWLPTDHPLVSMPNVVLTPHIGG 289 AR + D AL +A++ G +AA GLD + E +PL+ +PNVV TPH+G Sbjct 227 AARGGIIDEKALYNAIKEGIVAAVGLDVLEVEPKYNVEHQDFHNPLLELPNVVFTPHLGA 286 Query 290 ATWNTEARQARMVADDLGALLSGNRPAHVVN 320 +T+ + + +A ++ + L+GN ++VN Sbjct 287 STYEAQENISIAIAQEVISALNGNLYGNIVN 317 >gi|238763451|ref|ZP_04624414.1| D-3-phosphoglycerate dehydrogenase [Yersinia kristensenii ATCC 33638] gi|238763532|ref|ZP_04624494.1| D-3-phosphoglycerate dehydrogenase [Yersinia kristensenii ATCC 33638] gi|238698314|gb|EEP91069.1| D-3-phosphoglycerate dehydrogenase [Yersinia kristensenii ATCC 33638] gi|238698395|gb|EEP91149.1| D-3-phosphoglycerate dehydrogenase [Yersinia kristensenii ATCC 33638] Length=317 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 106/290 (37%), Positives = 160/290 (56%), Gaps = 32/290 (11%) Query 55 ADVLVVESDSVGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAE 112 AD LV D + V + L+++A TR P N+D+ AT GIPV++TP RN+DA AE Sbjct 25 ADFLVTSYDDITARVIKACPQLKLIACTRASPVNIDVKAATERGIPVIYTPGRNSDAAAE 84 Query 113 MTVALLLAVARHLIPADADVRSG------------------NIFRDGTIPYQRFRGAEIA 154 +T+AL+L VARH+ A + ++ G ++ +D PY+ F+G E+ Sbjct 85 LTIALMLNVARHIPQAHSALKQGQFTATEQSHFGLKTDVVWDVTKDS--PYEVFKGIELR 142 Query 155 GLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPY-----RDDAG---HSLDELLAEADIVS 206 T G+VG G++G+ V G++++ DPY D+ G +L++L ++AD VS Sbjct 143 NKTLGIVGYGSIGQRVGRIARAFGMQLLVADPYVSEVELDEPGIHKSTLEQLFSQADFVS 202 Query 207 MHAAVTDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTG 266 +H VT T G+I A F+ M+ A F+NT+R+ + L+DALR +LA A LD + Sbjct 203 LHLKVTPQTEGLIDAHLFSLMKPEAYFINTSRAAVVVEQHLIDALRHKQLAGAALDVYAH 262 Query 267 EWLPTDHPLV-SMPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRP 315 E + HP + NVV+TPHI GAT T + M+A D+ L N P Sbjct 263 EPIHASHPFIHEFDNVVITPHIAGATRETLVKHTAMIAQDIERFLR-NEP 311 >gi|315925550|ref|ZP_07921760.1| D-3-phosphoglycerate dehydrogenase [Pseudoramibacter alactolyticus ATCC 23263] gi|315621091|gb|EFV01062.1| D-3-phosphoglycerate dehydrogenase [Pseudoramibacter alactolyticus ATCC 23263] Length=346 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 105/349 (31%), Positives = 176/349 (51%), Gaps = 40/349 (11%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVA--ADVLVVESD 63 + TA L ++ ++ D W + A+ L D T A ADV++ D Sbjct 3 KIFFTAEYDEEALKPLYQIGEITKDGW------AVGKAKMLEDEFTKKAKDADVIITSYD 56 Query 64 SVGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAV 121 V V E L+++A TR P NVD+ A+ IPV++TP RN+D AEMT+AL+L++ Sbjct 57 DVTRKVIESAPNLKLIAVTRATPVNVDVAAASERNIPVIYTPGRNSDCTAEMTIALMLSI 116 Query 122 ARHLIPADADVRSGNIFRDGTI--------------------PYQRFRGAEIAGLTAGLV 161 AR + A + ++SG D + PY F+G ++ G T G+V Sbjct 117 ARKIPMAYSALKSGEFTADPSYKKVTKKGLKEDMVWDMKPGSPYVVFKGKQLKGSTLGIV 176 Query 162 GLGAVGRAVRWRLSGLGLRVIAHDPYR-----DDAG----HSLDELLAEADIVSMHAAVT 212 G G+VGR V +G++++ +DP+ +D G +L+EL++++D V+ H +T Sbjct 177 GYGSVGRRVGKIARAIGMQLLIYDPFCCPIDIEDIGIKKVENLEELMSQSDFVTCHLKIT 236 Query 213 DDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTD 272 +T +I + M+ A F+N +R + D +A+++AL+ K+A A D + E + ++ Sbjct 237 PETKKIINKKMINLMKPSAYFINASRGAILDEEAIIEALKNRKIAGAAFDVYASEPITSN 296 Query 273 HPLVS-MPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRPAHVVN 320 HP ++ + NVV+TPHI GAT R +D+ G + N Sbjct 297 HPYITDLDNVVITPHIAGATMAVLENHTRQFVEDIIRFTQGKTLLYQYN 345 >gi|291299076|ref|YP_003510354.1| phosphoglycerate dehydrogenase [Stackebrandtia nassauensis DSM 44728] gi|290568296|gb|ADD41261.1| Phosphoglycerate dehydrogenase [Stackebrandtia nassauensis DSM 44728] Length=324 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 133/331 (41%), Positives = 170/331 (52%), Gaps = 28/331 (8%) Query 6 RALVTAPLRGPGFAQLRRL----ADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVE 61 R LVT PG R L DVV+ + D R S LA +T D +V Sbjct 5 RVLVTTAWLSPGDEVHRLLTDAGCDVVHSSFND----RDSSPATLAALVTGF--DGIVAG 58 Query 62 SDSVGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLL 119 +D V L+V T N+D+ AT GI V TP N +VAE T ALLL Sbjct 59 TDRFSAEVIAAADRLKVFGRTGVGYDNIDVAAATERGIAVCPTPGVNRQSVAEHTFALLL 118 Query 120 AVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGL 179 +VAR + GN+ + + G E++G T GL+GLGA+G+AV G G+ Sbjct 119 SVARGV--------PGNVTAVAAGDWPQVSGRELSGATLGLIGLGAIGKAVARIALGFGM 170 Query 180 RVIAHDPYRDDAG--------HSLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGA 231 RVIAHDPY D SLDELLA AD VS+H + D T +I A+ A M+ GA Sbjct 171 RVIAHDPYLDAEAVAASGVERASLDELLATADFVSLHIFLDDATRHLIDAEAIATMKPGA 230 Query 232 VFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMPNVVLTPHIGGAT 291 +NT+R + D AL ALR G+L+ AGLD E LP D PL + N+++T HIG AT Sbjct 231 YLVNTSRGGVVDETALAAALREGRLSGAGLDVLETEPLPPDSPLRGLDNLIITAHIGAAT 290 Query 292 WNTEARQARMVADDLGALLSGNRPAHVVNPE 322 + AR RM A + +L G P HVVNPE Sbjct 291 VESRARSGRMAAQAVIDVLDGRTPEHVVNPE 321 >gi|148508253|gb|ABQ76039.1| phosphoglycerate dehydrogenase [uncultured haloarchaeon] Length=361 Score = 177 bits (448), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 126/353 (36%), Positives = 183/353 (52%), Gaps = 43/353 (12%) Query 8 LVTAPLRGPGFAQLRRLA-DVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 +T+ G +L L DV++ P I+ R R+ + L R+ V D+ + + V Sbjct 11 FITSNFTESGIERLTELGFDVIFHP-IETRDGRM-PVDTLTQRLEGV--DIFISGFEGVP 66 Query 67 GPVFERG--LRVVAATRGDP-SNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 + + LR++A RG P ++VDI AT GIPVL+ P RNA+ VA+ T+ LLLA R Sbjct 67 AELMDAADDLRLIACPRGGPEASVDISAATDRGIPVLYAPGRNAETVADHTMGLLLAATR 126 Query 124 HLIPADADVRSGNIFRD----------------------GTIPYQRFRGAEIAGLTAGLV 161 ++ A +R G RD PY RG E+ T G+V Sbjct 127 NIAQAHHRLRMG---RDTGTPQEDAAAGGEREDVTWGIGSESPYTTLRGPELRDRTIGIV 183 Query 162 GLGAVGRAVRWRL-SGLGLRVIAHDPYRD---------DAGHSLDELLAEADIVSMHAAV 211 G +GR V R G G+ V A+DP+ D D + L ++D+VS+HAAV Sbjct 184 GFSRIGRRVAKRAGDGFGMDVRAYDPFVDHVEMEPFQVDKVTDVQSLCQQSDVVSLHAAV 243 Query 212 TDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPT 271 + MIG +FAAM D F+NTAR+ L + AL++ALR ++ AA LD + E + Sbjct 244 APGSRNMIGPAEFAAMPDDGYFVNTARAALIEDGALIEALRTDEIQAAALDVYPEEPIAE 303 Query 272 DHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRPAHVVNPEVL 324 D+PL+ M NVV TPHI A+ + R + + +D+ ALL+ +P HVVNPE L Sbjct 304 DNPLLEMENVVTTPHIASASQDVIERHSELTVNDITALLNDEQPMHVVNPETL 356 >gi|255036888|ref|YP_003087509.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Dyadobacter fermentans DSM 18053] gi|254949644|gb|ACT94344.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Dyadobacter fermentans DSM 18053] Length=334 Score = 177 bits (448), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 116/321 (37%), Positives = 174/321 (55%), Gaps = 16/321 (4%) Query 6 RALVTAPLRGPGFAQLRR-LADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDS 64 + L+TAP L+ +V+Y PW Q R Y+ +L+ + AD L+ E D Sbjct 2 KILITAPYHDKAQQVLKEHFGEVIYKPWKLQE--RAYNEAELSALLRETGADALITEHDH 59 Query 65 VGGPVFER--GLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVA 122 V V GL+ + RG PSNV + AT+ GIPV +TPARNA AVAEM +A L+ + Sbjct 60 VTPAVITAFPGLQFIGVCRGTPSNVAVATATSLGIPVFNTPARNAQAVAEMFIANLITLM 119 Query 123 RHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVI 182 R+ + A ++ G+ Y +F+G EIAG T G+VG GAVG+ + + +++ Sbjct 120 RNTLAGIAWLKGGHWEAGAHTSYLQFKGNEIAGKTIGMVGFGAVGQTIANLVKHFPAQIL 179 Query 183 AHDPY--RDDAGH---SLDELLAEADIVSMHAAVTDDTIGMIGAQQFAAMRDGAVFLNTA 237 +DP+ DD + SL+++ +D+VS+H VT +T GMIGA+ M+ A+F+NTA Sbjct 180 YYDPFYTSDDPDYQKVSLEDVFRLSDVVSIHLPVTPETEGMIGAELIGLMKKDAIFVNTA 239 Query 238 RSQLRDTDALVDALRGGKLAAAGLDHFTGEWLP---TDHPLVSMPNVVLTPHIGGATWNT 294 R+ + + L+ A+ + A LD F E P D+ L+ NV+ TPHI GAT+ Sbjct 240 RAVVVQREVLLAAIESHAIRGAILDVFDHE--PPDALDYRLIHHQNVLATPHIAGATFEV 297 Query 295 EARQARMVADD-LGALLSGNR 314 E A ++ LG GNR Sbjct 298 EDHHADIMNKALLGFYKEGNR 318 >gi|123442827|ref|YP_001006803.1| putative oxidoreductase [Yersinia enterocolitica subsp. enterocolitica 8081] gi|122089788|emb|CAL12641.1| putative oxidoreductase [Yersinia enterocolitica subsp. enterocolitica 8081] Length=338 Score = 176 bits (447), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 115/339 (34%), Positives = 180/339 (54%), Gaps = 37/339 (10%) Query 6 RALVTAPLRGPGFAQLRRLADVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSV 65 + L TA G +L ++V W +P S EQL AD LV D + Sbjct 2 KTLFTAEYAG-SLDHFHQLGELVISGWAAGKPK--LSEEQLI--ALGHDADFLVTSYDDI 56 Query 66 GGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 V + L+++A TR +P N+D+ AT GIPV++TP RN+DA AE+T+AL+L +AR Sbjct 57 TARVIKACPQLKLIACTRANPVNIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLAR 116 Query 124 HL---------------IPADADVRSG---NIFRDGTIPYQRFRGAEIAGLTAGLVGLGA 165 H+ P +A +++ ++ +D PY+ F+G E+ T G+VG G+ Sbjct 117 HIPQAHSALKQRQFTATTPGNAGLKTDVVWDVTKDS--PYEVFKGVELRNKTLGIVGYGS 174 Query 166 VGRAVRWRLSGLGLRVIAHDPY-----RDDAG---HSLDELLAEADIVSMHAAVTDDTIG 217 +G+ V G++++ DPY D+ G +L+ L +++D V++H VT T+G Sbjct 175 IGQRVGRIARAFGMQLLVADPYVSEVELDEPGIHKTTLERLFSQSDFVTLHVKVTPQTVG 234 Query 218 MIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLV- 276 +I + F+ M+ A F+NT+R+ + LVDALR +LA A LD + E + +HP + Sbjct 235 LIDTRLFSLMKPEAYFINTSRAAVVVEQHLVDALRHKQLAGAALDVYAHEPIHANHPFIH 294 Query 277 SMPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRP 315 NVV+TPHI GAT T + M+A D+ L N P Sbjct 295 EFDNVVITPHIAGATHETLVKHTAMIAQDIERFLR-NEP 332 >gi|333980430|ref|YP_004518375.1| phosphoglycerate dehydrogenase [Desulfotomaculum kuznetsovii DSM 6115] gi|333823911|gb|AEG16574.1| Phosphoglycerate dehydrogenase [Desulfotomaculum kuznetsovii DSM 6115] Length=349 Score = 176 bits (447), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 112/281 (40%), Positives = 158/281 (57%), Gaps = 20/281 (7%) Query 55 ADVLVVESDSVGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAE 112 AD+LVV V V E LR++A R P NVD+ A + GIPV+H P R AD+ A+ Sbjct 70 ADILVVHKAPVTEEVIEGAPRLRLIACARAHPVNVDVRAALSRGIPVVHAPGRAADSTAD 129 Query 113 MTVALLLAVARHLIPADADVRSGNIFRDGTIPYQ-----RFRGAEIAGLTAGLVGLGAVG 167 +T+ALLL +AR++ VR R G +Q R G E+AG G++G G VG Sbjct 130 LTMALLLFLARNMGETCRLVR-----RLGAGAWQYDCRSRLEGVELAGKILGIIGFGQVG 184 Query 168 RAVRWRLSGLGLRVIAHDPYRDD-----AGH---SLDELLAEADIVSMHAAVTDDTIGMI 219 R V R G+ ++ + P+ D AG +L+ELL+ +D VS+H + IG+I Sbjct 185 RRVAVRAQAFGMNLLVYSPHVDPVEILAAGGRPVTLEELLSASDFVSLHTRPAPEKIGLI 244 Query 220 GAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTDHPLVSMP 279 GA Q A M++ A +NTAR +L D DAL AL+ ++ AA LD E P DHP ++P Sbjct 245 GAPQLALMKNSACLINTARGELVDEDALYRALKEKRIRAAALDVLISEPPPPDHPFFTLP 304 Query 280 NVVLTPHIGGATWNTEARQARMVADDLGALLSGNRPAHVVN 320 NVVLTPH+GG T R A+++ +++ LSG HV+ Sbjct 305 NVVLTPHLGGKTEAAPMRAAKIIIEEIINFLSGKSLRHVIT 345 >gi|320531069|ref|ZP_08032098.1| 4-phosphoerythronate dehydrogenase [Selenomonas artemidis F0399] gi|320136651|gb|EFW28604.1| 4-phosphoerythronate dehydrogenase [Selenomonas artemidis F0399] Length=341 Score = 176 bits (445), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 106/285 (38%), Positives = 163/285 (58%), Gaps = 24/285 (8%) Query 44 EQLADRITAVAADVLVVESDSVGGPVFE--RGLRVVAATRGDPSNVDIPGATAAGIPVLH 101 EQL D A++L+ + + V + L++V R N+++P A+A G+ V H Sbjct 66 EQLRD------AEILITQFCPITKKVLDACTKLKLVGVLRAGYENINVPYASAKGVAVFH 119 Query 102 TPARNADAVAEMTVALLLAVARHLIPADADVRSGNIFRD----GTIPYQRFRGAEIAGLT 157 TP RNA AVA+ TV +LLA R++ A A+++ G RD G +P ++ G T Sbjct 120 TPGRNATAVADFTVGMLLAECRNIAKAHANLKEGRWVRDYANAGAVP-------DLEGKT 172 Query 158 AGLVGLGAVGRAVRWRLSGLGLRVIAHDPYRDDAGH-----SLDELLAEADIVSMHAAVT 212 G++G+G VG V RL G G+ ++ +DPY + SLD+LL +AD V++H+ ++ Sbjct 173 VGIIGMGQVGVKVAHRLHGFGVHLLGYDPYATVFPNFVTQVSLDDLLTQADFVTLHSRLS 232 Query 213 DDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPTD 272 D+T M+ A+ F+ M+ A F+NTAR+ L D AL ALR +L A LD F E D Sbjct 233 DETKHMMNARAFSLMKPTAYFINTARAGLVDEAALAAALRDKQLQGAALDVFEHEPPAAD 292 Query 273 HPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRPAH 317 PLV +PNV +TPH+ G T + R ++A+ + + LSG+R +H Sbjct 293 DPLVRLPNVTITPHLAGGTTDAFLRSPVLLAEAMASALSGDRSSH 337 >gi|110668011|ref|YP_657822.1| phosphoglycerate dehydrogenase [Haloquadratum walsbyi DSM 16790] gi|109625758|emb|CAJ52193.1| phosphoglycerate dehydrogenase [Haloquadratum walsbyi DSM 16790] Length=354 Score = 176 bits (445), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 125/353 (36%), Positives = 183/353 (52%), Gaps = 43/353 (12%) Query 8 LVTAPLRGPGFAQLRRLA-DVVYDPWIDQRPLRIYSAEQLADRITAVAADVLVVESDSVG 66 +T+ G +L L DV++ P I+ R R+ + L R+ V D+ + + V Sbjct 4 FITSNFTESGIERLTELGFDVIFHP-IETRDGRM-PVDTLTQRLEGV--DIFISGFEGVP 59 Query 67 GPVFERG--LRVVAATRGDP-SNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVAR 123 + + L+++A RG P ++VDI AT GIPVL+ P RNA+ VA+ T+ LLLA R Sbjct 60 AELMDAADDLKLIACPRGGPEASVDISAATDRGIPVLYAPGRNAETVADHTMGLLLAATR 119 Query 124 HLIPADADVRSGNIFRD----------------------GTIPYQRFRGAEIAGLTAGLV 161 ++ A +R G RD PY RG E+ T G+V Sbjct 120 NIAQAHHRLRMG---RDTGTPQEDAAAGGEREDVTWGIGSESPYTTLRGPELRDRTIGIV 176 Query 162 GLGAVGRAVRWRL-SGLGLRVIAHDPYRD---------DAGHSLDELLAEADIVSMHAAV 211 G +GR V R G G+ V A+DP+ D D + L ++D+VS+HAAV Sbjct 177 GFSRIGRRVAKRAGDGFGMDVRAYDPFVDHVEMEPFQVDKVTDVQSLCQQSDVVSLHAAV 236 Query 212 TDDTIGMIGAQQFAAMRDGAVFLNTARSQLRDTDALVDALRGGKLAAAGLDHFTGEWLPT 271 + MIG +FAAM D F+NTAR+ L + AL++ALR ++ AA LD + E + Sbjct 237 APGSRNMIGPAEFAAMPDDGYFVNTARAALIEDGALIEALRTDEIQAAALDVYPEEPIAE 296 Query 272 DHPLVSMPNVVLTPHIGGATWNTEARQARMVADDLGALLSGNRPAHVVNPEVL 324 D+PL+ M NVV TPHI A+ + R + + +D+ ALL+ +P HVVNPE L Sbjct 297 DNPLLEMENVVTTPHIASASQDVIERHSELTVNDITALLNDEQPMHVVNPETL 349 Lambda K H 0.321 0.137 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 580252432782 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40