BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0770 Length=295 Score E Sequences producing significant alignments: (Bits) Value gi|15607910|ref|NP_215284.1| dehydrogenase/reductase [Mycobacter... 586 1e-165 gi|253797716|ref|YP_003030717.1| dehydrogenase/reductase [Mycoba... 584 7e-165 gi|31791958|ref|NP_854451.1| dehydrogenase/reductase [Mycobacter... 583 1e-164 gi|340625789|ref|YP_004744241.1| putative dehydrogenase/reductas... 577 8e-163 gi|148660547|ref|YP_001282070.1| putative dehydrogenase/reductas... 555 2e-156 gi|240171684|ref|ZP_04750343.1| putative dehydrogenase/reductase... 433 2e-119 gi|169628313|ref|YP_001701962.1| dehydrogenase/reductase [Mycoba... 382 3e-104 gi|183984894|ref|YP_001853185.1| dehydrogenase/reductase [Mycoba... 373 2e-101 gi|118474010|ref|YP_890084.1| oxidoreductase [Mycobacterium smeg... 372 4e-101 gi|120406103|ref|YP_955932.1| 6-phosphogluconate dehydrogenase [... 368 7e-100 gi|118462661|ref|YP_879990.1| oxidoreductase [Mycobacterium aviu... 358 6e-97 gi|254773653|ref|ZP_05215169.1| oxidoreductase [Mycobacterium av... 357 9e-97 gi|254818453|ref|ZP_05223454.1| oxidoreductase [Mycobacterium in... 357 1e-96 gi|322812817|pdb|3QHA|A Chain A, Crystal Structure Of A Putative... 357 1e-96 gi|41406702|ref|NP_959538.1| hypothetical protein MAP0604 [Mycob... 355 6e-96 gi|145222194|ref|YP_001132872.1| 6-phosphogluconate dehydrogenas... 355 7e-96 gi|126437524|ref|YP_001073215.1| 6-phosphogluconate dehydrogenas... 354 9e-96 gi|108801539|ref|YP_641736.1| 6-phosphogluconate dehydrogenase p... 354 1e-95 gi|336458366|gb|EGO37344.1| beta-hydroxyacid dehydrogenase, 3-hy... 353 2e-95 gi|342862188|ref|ZP_08718830.1| oxidoreductase [Mycobacterium co... 353 3e-95 gi|333992238|ref|YP_004524852.1| dehydrogenase/reductase [Mycoba... 348 7e-94 gi|296166484|ref|ZP_06848915.1| 3-hydroxyisobutyrate dehydrogena... 344 9e-93 gi|111021633|ref|YP_704605.1| 2-hydroxy-3-oxopropionate reductas... 330 2e-88 gi|226364169|ref|YP_002781951.1| oxidoreductase [Rhodococcus opa... 325 4e-87 gi|319950418|ref|ZP_08024334.1| 6-phosphogluconate dehydrogenase... 316 2e-84 gi|54026634|ref|YP_120876.1| putative oxidoreductase [Nocardia f... 316 3e-84 gi|226306871|ref|YP_002766831.1| oxidoreductase [Rhodococcus ery... 314 8e-84 gi|312138808|ref|YP_004006144.1| 6-phosphogluconate dehydrogenas... 314 1e-83 gi|343927853|ref|ZP_08767321.1| putative oxidoreductase [Gordoni... 312 4e-83 gi|325676492|ref|ZP_08156170.1| 3-hydroxyisobutyrate dehydrogena... 311 6e-83 gi|262203712|ref|YP_003274920.1| 3-hydroxyisobutyrate dehydrogen... 309 4e-82 gi|229492750|ref|ZP_04386551.1| hypothetical oxidoreductase [Rho... 303 2e-80 gi|326384244|ref|ZP_08205926.1| 3-hydroxyisobutyrate dehydrogena... 254 9e-66 gi|326331684|ref|ZP_08197972.1| 3-hydroxyisobutyrate dehydrogena... 218 1e-54 gi|254481193|ref|ZP_05094438.1| hypothetical protein GPB2148_166... 149 4e-34 gi|333992135|ref|YP_004524749.1| 3-hydroxyisobutyrate dehydrogen... 135 1e-29 gi|108800659|ref|YP_640856.1| 6-phosphogluconate dehydrogenase p... 132 4e-29 gi|118470062|ref|YP_889072.1| 6-phosphogluconate dehydrogenase, ... 131 1e-28 gi|120405127|ref|YP_954956.1| 6-phosphogluconate dehydrogenase [... 130 2e-28 gi|126436283|ref|YP_001071974.1| 6-phosphogluconate dehydrogenas... 129 4e-28 gi|220935102|ref|YP_002514001.1| oxidoreductase [Thioalkalivibri... 128 1e-27 gi|332981071|ref|YP_004462512.1| tartronate semialdehyde reducta... 127 1e-27 gi|150390719|ref|YP_001320768.1| tartronate semialdehyde reducta... 127 2e-27 gi|336247317|ref|YP_004591027.1| tartronate semialdehyde reducta... 127 2e-27 gi|315443525|ref|YP_004076404.1| beta-hydroxyacid dehydrogenase,... 126 4e-27 gi|117625425|ref|YP_858748.1| tartronate semialdehyde reductase ... 125 5e-27 gi|170766167|ref|ZP_02900978.1| 2-hydroxy-3-oxopropionate reduct... 125 5e-27 gi|162138369|ref|YP_542533.2| tartronate semialdehyde reductase ... 125 6e-27 gi|312968534|ref|ZP_07782743.1| 2-hydroxy-3-oxopropionate reduct... 125 6e-27 gi|300897878|ref|ZP_07116261.1| 2-hydroxy-3-oxopropionate reduct... 125 7e-27 >gi|15607910|ref|NP_215284.1| dehydrogenase/reductase [Mycobacterium tuberculosis H37Rv] gi|15840185|ref|NP_335222.1| 3-hydroxyisobutyrate dehydrogenase family protein [Mycobacterium tuberculosis CDC1551] gi|121636694|ref|YP_976917.1| putative dehydrogenase/reductase [Mycobacterium bovis BCG str. Pasteur 1173P2] 66 more sequence titles Length=295 Score = 586 bits (1511), Expect = 1e-165, Method: Compositional matrix adjust. Identities = 295/295 (100%), Positives = 295/295 (100%), Gaps = 0/295 (0%) Query 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV Sbjct 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 Query 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH Sbjct 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 Query 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN Sbjct 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 Query 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR Sbjct 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET Sbjct 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 >gi|253797716|ref|YP_003030717.1| dehydrogenase/reductase [Mycobacterium tuberculosis KZN 1435] gi|289553028|ref|ZP_06442238.1| dehydrogenase/reductase [Mycobacterium tuberculosis KZN 605] gi|297633280|ref|ZP_06951060.1| dehydrogenase/reductase [Mycobacterium tuberculosis KZN 4207] 6 more sequence titles Length=295 Score = 584 bits (1505), Expect = 7e-165, Method: Compositional matrix adjust. Identities = 294/295 (99%), Positives = 294/295 (99%), Gaps = 0/295 (0%) Query 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV Sbjct 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 Query 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH Sbjct 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 Query 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN Sbjct 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 Query 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 MLT VSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR Sbjct 181 MLTLVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET Sbjct 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 >gi|31791958|ref|NP_854451.1| dehydrogenase/reductase [Mycobacterium bovis AF2122/97] gi|31617545|emb|CAD93655.1| PROBABLE DEHYDROGENASE/REDUCTASE [Mycobacterium bovis AF2122/97] Length=295 Score = 583 bits (1502), Expect = 1e-164, Method: Compositional matrix adjust. Identities = 294/295 (99%), Positives = 294/295 (99%), Gaps = 0/295 (0%) Query 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV Sbjct 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 Query 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH Sbjct 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 Query 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 IVDAP SGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN Sbjct 121 IVDAPGSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 Query 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR Sbjct 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET Sbjct 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 >gi|340625789|ref|YP_004744241.1| putative dehydrogenase/reductase [Mycobacterium canettii CIPT 140010059] gi|340003979|emb|CCC43114.1| putative dehydrogenase/reductase [Mycobacterium canettii CIPT 140010059] Length=295 Score = 577 bits (1487), Expect = 8e-163, Method: Compositional matrix adjust. Identities = 290/295 (99%), Positives = 292/295 (99%), Gaps = 0/295 (0%) Query 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 MTAHPETPRLGYIGLGNQGAPM KRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV Sbjct 1 MTAHPETPRLGYIGLGNQGAPMVKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 Query 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 AEADIISITVFDDAQV SVITADNGLATHAKPGTIVAIHSTI+DTTAVDLAEKLKPQGIH Sbjct 61 AEADIISITVFDDAQVRSVITADNGLATHAKPGTIVAIHSTISDTTAVDLAEKLKPQGIH 120 Query 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 IVDAPVSGGAAAAAKGELAVMVGAD EAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN Sbjct 121 IVDAPVSGGAAAAAKGELAVMVGADGEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 Query 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR Sbjct 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVP+PDTEPAKET Sbjct 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPYPDTEPAKET 295 >gi|148660547|ref|YP_001282070.1| putative dehydrogenase/reductase [Mycobacterium tuberculosis H37Ra] gi|148504699|gb|ABQ72508.1| putative dehydrogenase/reductase [Mycobacterium tuberculosis H37Ra] Length=281 Score = 555 bits (1431), Expect = 2e-156, Method: Compositional matrix adjust. Identities = 280/281 (99%), Positives = 281/281 (100%), Gaps = 0/281 (0%) Query 15 LGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISITVFDDA 74 +GNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISITVFDDA Sbjct 1 MGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISITVFDDA 60 Query 75 QVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAA 134 QVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAA Sbjct 61 QVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAA 120 Query 135 KGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQ 194 KGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQ Sbjct 121 KGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQ 180 Query 195 RLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRGLGEKDL 254 RLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRGLGEKDL Sbjct 181 RLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRGLGEKDL 240 Query 255 SLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 295 SLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET Sbjct 241 SLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPAKET 281 >gi|240171684|ref|ZP_04750343.1| putative dehydrogenase/reductase [Mycobacterium kansasii ATCC 12478] Length=290 Score = 433 bits (1113), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 232/281 (83%), Positives = 256/281 (92%), Gaps = 0/281 (0%) Query 8 PRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIIS 67 PRLGYIGLGNQGAPMAKR LDWPGGLTVFDVR EAM PFVEGGATAAASV++VA ADIIS Sbjct 5 PRLGYIGLGNQGAPMAKRYLDWPGGLTVFDVRAEAMEPFVEGGATAAASVAEVAGADIIS 64 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 +TV DDAQV SVIT D+GLA +AK GTI+AIHSTI+DTTAV+LA +L+PQG+H+VDAPVS Sbjct 65 VTVLDDAQVRSVITGDDGLAANAKTGTIIAIHSTISDTTAVELARQLEPQGVHVVDAPVS 124 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA AAA+G+LA MVGADDE FQRIKEPF RWASL+IHAGEPGAGTRMKLARNMLTFVSY Sbjct 125 GGAGAAAEGKLATMVGADDETFQRIKEPFRRWASLVIHAGEPGAGTRMKLARNMLTFVSY 184 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTR 247 AAAAEA++LAEA GL L +L KVVRHSD+ TGG GAIMFR TTA M+P DPLRPLLEHTR Sbjct 185 AAAAEAEKLAEASGLSLRSLAKVVRHSDALTGGPGAIMFRETTAAMKPDDPLRPLLEHTR 244 Query 248 GLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPD 288 LGEKDLSLALALGE +SV+LPLA+LAL+RLAAGLGVPHPD Sbjct 245 ALGEKDLSLALALGESLSVELPLAKLALERLAAGLGVPHPD 285 >gi|169628313|ref|YP_001701962.1| dehydrogenase/reductase [Mycobacterium abscessus ATCC 19977] gi|169240280|emb|CAM61308.1| Probable dehydrogenase/reductase [Mycobacterium abscessus] Length=288 Score = 382 bits (982), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 190/280 (68%), Positives = 227/280 (82%), Gaps = 3/280 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 +LGYIGLGN GAPMA+RL+DWPGGLTVFD+R EA+AP VE GA A+ V+D+A+AD+IS+ Sbjct 7 KLGYIGLGNMGAPMARRLVDWPGGLTVFDLRAEAVAPLVEEGAVGASDVADIADADLISV 66 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV DDAQV V+ +A AKPGTI+AIHSTI+DTTAV+LA+ +P+ IH++DAPVSG Sbjct 67 TVLDDAQVRQVV---GQVAPKAKPGTIIAIHSTISDTTAVELAQAWRPRDIHVIDAPVSG 123 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA A KGELA MVGAD E F R+KE FS+WASL+IHAG PGAGTRMKLARN+L FV++ Sbjct 124 GAPGAHKGELATMVGADGETFARVKEAFSKWASLVIHAGAPGAGTRMKLARNLLHFVAFT 183 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EAQRLAE+CGLD+ LGKVVRH+D+ TGG GAIM R+TT P+ P P+ H RG Sbjct 184 AAGEAQRLAESCGLDITDLGKVVRHTDAITGGPGAIMLRDTTEPVTPDSFWLPIFTHVRG 243 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPD 288 LGEKDLSLALALGE SVDLPLA LA ++LAA LGVPH + Sbjct 244 LGEKDLSLALALGEEQSVDLPLATLAREQLAASLGVPHEE 283 >gi|183984894|ref|YP_001853185.1| dehydrogenase/reductase [Mycobacterium marinum M] gi|183178220|gb|ACC43330.1| dehydrogenase/reductase [Mycobacterium marinum M] Length=288 Score = 373 bits (958), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 197/281 (71%), Positives = 229/281 (82%), Gaps = 0/281 (0%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E P+LGYIGLGNQGAPMAKRLLDWPGGL V+DVR EAM P E GA+AAASV++VA ADI Sbjct 3 EHPKLGYIGLGNQGAPMAKRLLDWPGGLVVYDVRAEAMTPLAEAGASAAASVAEVAGADI 62 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 IS+TV +DAQV VIT NGLA HA+ GTI+AIHSTI+DTTA +LA +L+P+GIH++DAP Sbjct 63 ISVTVLNDAQVREVITGANGLAAHARAGTIIAIHSTISDTTAEELARELRPRGIHVIDAP 122 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGA AA+KG+LA MVGA D+ F R+KEPFS WASL++HAG PGAGTRMKLARNMLTF Sbjct 123 VSGGAGAASKGQLATMVGAGDDVFARVKEPFSCWASLVVHAGPPGAGTRMKLARNMLTFT 182 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 YAA EA +LAEA G++L LG VVRH+D T GAG+IMFR+ T +EP L H Sbjct 183 IYAAVGEAWKLAEASGVNLQDLGNVVRHTDKLTSGAGSIMFRDNTKDLEPGHFLYDGFVH 242 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 R LGEKDL LALALGE +SVDLPLA+LAL+RLA GLGVPH Sbjct 243 ARDLGEKDLGLALALGEALSVDLPLARLALERLAPGLGVPH 283 >gi|118474010|ref|YP_890084.1| oxidoreductase [Mycobacterium smegmatis str. MC2 155] gi|118175297|gb|ABK76193.1| putative oxidoreductase [Mycobacterium smegmatis str. MC2 155] Length=284 Score = 372 bits (955), Expect = 4e-101, Method: Compositional matrix adjust. Identities = 191/278 (69%), Positives = 224/278 (81%), Gaps = 3/278 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 +LGYIGLGNQGAPMAKRL DWPGGLTVFDVR EAMAP VE GA AA SV+ VA AD+IS+ Sbjct 5 KLGYIGLGNQGAPMAKRLADWPGGLTVFDVRAEAMAPLVELGAEAADSVAAVATADVISV 64 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +DAQV V+ LA HAKPGT+VAIHSTI TA +LAE+L+P+GIHIVDAPVSG Sbjct 65 TVLNDAQVRDVV---GQLAEHAKPGTVVAIHSTIEPGTAPELAEQLRPKGIHIVDAPVSG 121 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA AA KGELAVMVGADD+A+ +K F +WASL++ AGEPGAGTRMKLARNMLTF+ +A Sbjct 122 GAGAADKGELAVMVGADDDAYAAVKPVFKKWASLVVRAGEPGAGTRMKLARNMLTFIGFA 181 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 A+ EA +LAEA G+DL LG+VVRHSD+ +GG GAI+ R+ T P+ P L + HTRG Sbjct 182 ASCEAMKLAEAAGIDLQKLGRVVRHSDAQSGGPGAIIVRDDTKPLTPDHWLYDMFVHTRG 241 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 L EKDL+LAL LGE V V+LPLA +AL+RLA GLGVPH Sbjct 242 LAEKDLTLALGLGESVGVELPLAHIALERLADGLGVPH 279 >gi|120406103|ref|YP_955932.1| 6-phosphogluconate dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119958921|gb|ABM15926.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium vanbaalenii PYR-1] Length=290 Score = 368 bits (944), Expect = 7e-100, Method: Compositional matrix adjust. Identities = 187/286 (66%), Positives = 224/286 (79%), Gaps = 3/286 (1%) Query 1 MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV 60 M+ + R+GYIGLGNQGAPMAKRL+DWPGGL VFDVR EAM P VE GA+AA V+ V Sbjct 1 MSERADELRVGYIGLGNQGAPMAKRLVDWPGGLIVFDVRTEAMTPLVEMGASAADDVAGV 60 Query 61 AEADIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIH 120 + AD+IS+TV +DAQV V+ LA HA+PGT++AIHSTI TA +LAE+L+P+GIH Sbjct 61 SAADVISVTVLNDAQVRDVV---GELAAHAEPGTVIAIHSTIEPDTAPELAEQLRPKGIH 117 Query 121 IVDAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARN 180 IVDAPVSGGA AA KGELAVMVGAD+ A+ R+K F +WAS+++ AGEPGAGTRMKLARN Sbjct 118 IVDAPVSGGAGAADKGELAVMVGADEHAYDRVKPVFKQWASMVVRAGEPGAGTRMKLARN 177 Query 181 MLTFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 MLTFV + AA EA RLAEA G+DL LG+VVRHSD+ +GG GAIM R+ P+ P L Sbjct 178 MLTFVGFTAACEAMRLAEAAGIDLQKLGRVVRHSDAQSGGPGAIMVRDDMLPLAPEHFLY 237 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 + HTRGLGEKDL LAL LGE V+LPLA++AL+ LAAGLGVPH Sbjct 238 DMFVHTRGLGEKDLRLALGLGESTGVELPLAEIALRDLAAGLGVPH 283 >gi|118462661|ref|YP_879990.1| oxidoreductase [Mycobacterium avium 104] gi|118163948|gb|ABK64845.1| putative oxidoreductase [Mycobacterium avium 104] Length=292 Score = 358 bits (919), Expect = 6e-97, Method: Compositional matrix adjust. Identities = 197/285 (70%), Positives = 228/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA R+ +WPGG+TV+D+R+EAM P E GAT A SV+DVA AD+ Sbjct 10 EQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADL 69 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV DDAQV V+ LA HAKPGT++AIHSTI+DTTAV+LA LK + IHIVDAP Sbjct 70 IHITVLDDAQVREVV---GELAGHAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAP 126 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAA+GELA MVGAD E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 127 VSGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 186 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ +EP + L H Sbjct 187 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDNMKDLEPDNFLYQPFLH 246 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLA+LA + LAAGLGVPH + E Sbjct 247 TRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE 291 >gi|254773653|ref|ZP_05215169.1| oxidoreductase [Mycobacterium avium subsp. avium ATCC 25291] Length=292 Score = 357 bits (917), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 196/285 (69%), Positives = 228/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA R+ +WPGG+TV+D+R+EAM P E GAT A SV+DVA AD+ Sbjct 10 EQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADL 69 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV +DAQV V+ LA HAKPGT++AIHSTI+DTTAV+LA LK + IHIVDAP Sbjct 70 IHITVLNDAQVREVV---GELAAHAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAP 126 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAA+GELA MVGAD E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 127 VSGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 186 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ +EP + L H Sbjct 187 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDNMKDLEPDNFLYQPFLH 246 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLA+LA + LAAGLGVPH + E Sbjct 247 TRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE 291 >gi|254818453|ref|ZP_05223454.1| oxidoreductase [Mycobacterium intracellulare ATCC 13950] Length=285 Score = 357 bits (917), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 198/285 (70%), Positives = 226/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA ++ +WPGG+TVFD+R +AM P E GA A SV+DVA ADI Sbjct 3 EALKLGYIGLGNMGAPMATKMTEWPGGVTVFDIRTDAMTPLAEKGARLADSVADVAAADI 62 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV +DAQV V+ LA HA+PGT++AIHSTI+DTTAV+LA LK +GIHIVDAP Sbjct 63 IHITVLNDAQVREVV---GELAAHAEPGTVIAIHSTISDTTAVELARDLKERGIHIVDAP 119 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAAKGELA MVGAD E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 120 VSGGAAAAAKGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 179 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R +EP + L H Sbjct 180 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVREDMKDLEPDNFLYQPFLH 239 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLAQLA +RLAAGLGVPH E Sbjct 240 TRGLGEKDLSLALALGESVSVDLPLAQLAYERLAAGLGVPHTKKE 284 >gi|322812817|pdb|3QHA|A Chain A, Crystal Structure Of A Putative Oxidoreductase From Mycobacterium Avium 104 gi|322812818|pdb|3QHA|B Chain B, Crystal Structure Of A Putative Oxidoreductase From Mycobacterium Avium 104 Length=296 Score = 357 bits (916), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 197/285 (70%), Positives = 228/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA R+ +WPGG+TV+D+R+EAM P E GAT A SV+DVA AD+ Sbjct 14 EQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADL 73 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV DDAQV V+ LA HAKPGT++AIHSTI+DTTAV+LA LK + IHIVDAP Sbjct 74 IHITVLDDAQVREVV---GELAGHAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAP 130 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAA+GELA MVGAD E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 131 VSGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 190 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ +EP + L H Sbjct 191 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDNMKDLEPDNFLYQPFLH 250 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLA+LA + LAAGLGVPH + E Sbjct 251 TRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE 295 >gi|41406702|ref|NP_959538.1| hypothetical protein MAP0604 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395052|gb|AAS02921.1| hypothetical protein MAP_0604 [Mycobacterium avium subsp. paratuberculosis K-10] Length=292 Score = 355 bits (910), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 196/285 (69%), Positives = 227/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA R+ +WPGG+TV+D+R+EAM P E GAT A SV+DVA AD+ Sbjct 10 EQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADL 69 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV DDAQV V+ LA HAKPGT++AIHSTI+DTTAV+LA LK + IHIVDAP Sbjct 70 IHITVLDDAQVREVV---GELAGHAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAP 126 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAA+GELA MVGA E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 127 VSGGAAAAARGELATMVGAGREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 186 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ +EP + L H Sbjct 187 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDNMKDLEPDNFLYQPFLH 246 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLA+LA + LAAGLGVPH + E Sbjct 247 TRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHTEKE 291 >gi|145222194|ref|YP_001132872.1| 6-phosphogluconate dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|315442633|ref|YP_004075512.1| beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase [Mycobacterium sp. Spyr1] gi|145214680|gb|ABP44084.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium gilvum PYR-GCK] gi|315260936|gb|ADT97677.1| beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase [Mycobacterium sp. Spyr1] Length=284 Score = 355 bits (910), Expect = 7e-96, Method: Compositional matrix adjust. Identities = 188/278 (68%), Positives = 222/278 (80%), Gaps = 3/278 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 +LGYIGLGNQGAPMAKRL+DWPGGL VFDVR EAM P VE GAT A SV+DVA AD+IS+ Sbjct 7 KLGYIGLGNQGAPMAKRLVDWPGGLVVFDVRTEAMTPLVELGATLADSVADVAAADVISV 66 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +DAQV V+ LA HA+PGT++AIHSTI TA +LAE+L+P+GIHIVDAPVSG Sbjct 67 TVLNDAQVRDVVAE---LAAHAEPGTVIAIHSTIEPATAGELAEQLRPKGIHIVDAPVSG 123 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA AA KGELAVMVGAD+ A++R+K F +WAS+++ AGEPGAGTRMKLARNMLTF+ + Sbjct 124 GAGAAEKGELAVMVGADEHAYERVKPVFKKWASMVVRAGEPGAGTRMKLARNMLTFIGFT 183 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EA RLAEA G+DL LG+VVRHSD+ +GG GAIM R+ + P L + HTRG Sbjct 184 AACEAMRLAEASGIDLQKLGRVVRHSDAQSGGPGAIMVRDDMKALTPDHFLHDMFVHTRG 243 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 L EKDL LALALG+ VDLPLA++ALQ LAAGLGVPH Sbjct 244 LAEKDLKLALALGDETGVDLPLARIALQDLAAGLGVPH 281 >gi|126437524|ref|YP_001073215.1| 6-phosphogluconate dehydrogenase [Mycobacterium sp. JLS] gi|126237324|gb|ABO00725.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. JLS] Length=286 Score = 354 bits (908), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 182/281 (65%), Positives = 217/281 (78%), Gaps = 3/281 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 + GYIGLGN GAPMAKRL WPGGL VFDVR +AMAP VE GA A +V+DV +ADIISI Sbjct 5 KYGYIGLGNMGAPMAKRLTGWPGGLIVFDVRPDAMAPLVEAGAAQADNVADVGDADIISI 64 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +D QV V+ L AKPGT++AIHSTI+ TAV+LA++L+PQ IHIVDAPVSG Sbjct 65 TVLNDEQVRHVVAE---LVPRAKPGTVIAIHSTISPDTAVELAKELRPQDIHIVDAPVSG 121 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA AA KGELAVMVGA+ ++R+K F +WAS+++HAGEPGAGTRMKLARNMLTF +A Sbjct 122 GAGAAEKGELAVMVGAERPVYERVKPAFKQWASVVVHAGEPGAGTRMKLARNMLTFTGFA 181 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EA LAE GLDL ALG+VVRHSD+ +GG GAI+ R P++ + L + HTRG Sbjct 182 AACEAMTLAEKAGLDLQALGRVVRHSDAQSGGPGAIIVRENMRPLDHDNFLYDMFLHTRG 241 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDT 289 L EKDL LALALGE + VDLPLAQ+ALQ LA GLGVPH ++ Sbjct 242 LAEKDLGLALALGEELDVDLPLAQVALQNLADGLGVPHVES 282 >gi|108801539|ref|YP_641736.1| 6-phosphogluconate dehydrogenase protein [Mycobacterium sp. MCS] gi|119870693|ref|YP_940645.1| 6-phosphogluconate dehydrogenase [Mycobacterium sp. KMS] gi|108771958|gb|ABG10680.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. MCS] gi|119696782|gb|ABL93855.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. KMS] Length=286 Score = 354 bits (908), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 181/281 (65%), Positives = 217/281 (78%), Gaps = 3/281 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 + GYIGLGN GAPMAKRL WPGGL VFDVR +AMAP VE GA A +V+DVA+ADIISI Sbjct 5 KYGYIGLGNMGAPMAKRLTGWPGGLIVFDVRPDAMAPLVEAGAAQADNVADVADADIISI 64 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +D QV V+ L AKPGT++AIHSTI+ TAV+LA++L+ Q IH+VDAPVSG Sbjct 65 TVLNDEQVRHVVAE---LVPRAKPGTVIAIHSTISPDTAVELAKELRSQDIHVVDAPVSG 121 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA AA KGELAVMVGA+ ++R+K F +WAS+++HAGEPGAGTRMKLARNMLTF +A Sbjct 122 GAGAAEKGELAVMVGAERSVYERVKPAFKQWASVVVHAGEPGAGTRMKLARNMLTFTGFA 181 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EA LAE GLDL ALG+VVRHSD+ +GG GAI+ R P++ + L + HTRG Sbjct 182 AACEAMTLAEKAGLDLQALGRVVRHSDAQSGGPGAIIVRENMRPLDHDNFLYDMFLHTRG 241 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDT 289 L EKDL LAL LGE + VDLPLAQ+ALQ LAAGLGVPH ++ Sbjct 242 LAEKDLGLALTLGEELDVDLPLAQVALQNLAAGLGVPHVES 282 >gi|336458366|gb|EGO37344.1| beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase [Mycobacterium avium subsp. paratuberculosis S397] Length=292 Score = 353 bits (905), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 195/285 (69%), Positives = 226/285 (80%), Gaps = 3/285 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI 65 E +LGYIGLGN GAPMA R+ +WPGG+TV+D+R+EAM P E GAT A SV+DVA AD+ Sbjct 10 EQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADL 69 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I ITV DDAQV V+ LA HAKPGT++AIHSTI+DTTA +LA LK + IHIVDAP Sbjct 70 IHITVLDDAQVREVV---GELAGHAKPGTVIAIHSTISDTTAFELARDLKARDIHIVDAP 126 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGAAAAA+GELA MVGA E ++RIK F WA+++IHAGEPGAGTRMKLARNMLTF Sbjct 127 VSGGAAAAARGELATMVGAGREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFT 186 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 SYAAA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ +EP + L H Sbjct 187 SYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDNMKDLEPDNFLYQPFLH 246 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 TRGLGEKDLSLALALGE VSVDLPLA+LA + LAAGLGVPH + E Sbjct 247 TRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHTEKE 291 >gi|342862188|ref|ZP_08718830.1| oxidoreductase [Mycobacterium colombiense CECT 3035] gi|342130266|gb|EGT83586.1| oxidoreductase [Mycobacterium colombiense CECT 3035] Length=285 Score = 353 bits (905), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 191/282 (68%), Positives = 225/282 (80%), Gaps = 3/282 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 +LGYIGLGN GAPMA ++ +WPGG+TV+D+R EAM P E GA+ A SV+DVA ADII I Sbjct 6 KLGYIGLGNMGAPMATKMTEWPGGVTVYDIRTEAMTPLAEKGASLADSVADVAAADIIHI 65 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +D QV V+ LA AKPGT++AIHSTI+DTTAV+LA + KPQGIH++DAPVSG Sbjct 66 TVLNDTQVREVV---GELAATAKPGTVIAIHSTISDTTAVELAAEHKPQGIHVIDAPVSG 122 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GAAAAAKGELA MVGAD E +++IK F WA++++HAGEPGAGTRMKLARNMLTF SYA Sbjct 123 GAAAAAKGELATMVGADREVYEKIKPAFKHWAAMVVHAGEPGAGTRMKLARNMLTFTSYA 182 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EA +LAEA GLDL ALG+VVRH+D+ T G GAIM R+ +EP + L HTRG Sbjct 183 AACEAMKLAEAAGLDLQALGRVVRHTDALTSGPGAIMVRDDMKDIEPDNFLYEPFLHTRG 242 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 LGEKDLSLAL+LGE VSVDLPLAQLA QRLAA LGVPH + E Sbjct 243 LGEKDLSLALSLGEAVSVDLPLAQLAYQRLAASLGVPHKEEE 284 >gi|333992238|ref|YP_004524852.1| dehydrogenase/reductase [Mycobacterium sp. JDM601] gi|333488206|gb|AEF37598.1| dehydrogenase/reductase [Mycobacterium sp. JDM601] Length=262 Score = 348 bits (892), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 182/264 (69%), Positives = 213/264 (81%), Gaps = 6/264 (2%) Query 26 LLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV-AEADIISITVFDDAQVSSVITADN 84 ++DWPGG+TVFDVR EAM P VE GA +A +V++V A ADIIS+TV DDAQV V+ Sbjct 1 MVDWPGGVTVFDVRAEAMTPLVEAGAGSADNVAEVGASADIISVTVLDDAQVREVVAE-- 58 Query 85 GLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAKGELAVMVGA 144 LA +AKPGT++AIHSTIADTTA +LAE+LKPQGIH+VDAPVSGGA AA KG+LA MVGA Sbjct 59 -LAANAKPGTVIAIHSTIADTTAAELAEQLKPQGIHVVDAPVSGGAGAAEKGQLATMVGA 117 Query 145 DDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQRLAEACGLDL 204 D +++IK F WA+L+IHAGEPGAGTRMKLARNMLTF +YAAA EA +LAEA GLDL Sbjct 118 DRAVYEQIKPAFKHWAALVIHAGEPGAGTRMKLARNMLTFTAYAAAGEAMKLAEAAGLDL 177 Query 205 VALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADP-LRPLLEHTRGLGEKDLSLALALGEV 263 ALG+VVRH+D+ TGG GAIM ++TAP+ PAD L HTRGLGEKDLSLAL LG Sbjct 178 QALGRVVRHTDALTGGPGAIMLLDSTAPL-PADHFLHDAFTHTRGLGEKDLSLALGLGRA 236 Query 264 VSVDLPLAQLALQRLAAGLGVPHP 287 V+LPLAQ+ALQRLA GLGVPHP Sbjct 237 TGVELPLAQIALQRLAPGLGVPHP 260 >gi|296166484|ref|ZP_06848915.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898096|gb|EFG77671.1| 3-hydroxyisobutyrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=285 Score = 344 bits (883), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 191/282 (68%), Positives = 222/282 (79%), Gaps = 3/282 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 +LGYIGLGN GAPMA ++ +WPGG+TV+D+R EAM P E GA A SV+DVA ADII I Sbjct 6 KLGYIGLGNMGAPMATKMTEWPGGVTVYDIRTEAMTPLAEKGAGLADSVADVAAADIIHI 65 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV +DAQV V+ LA HAKPGT++AIHSTI+DTTAV+LA + KP GIH+VDAPVSG Sbjct 66 TVLNDAQVREVV---GELAAHAKPGTVIAIHSTISDTTAVELAAEHKPHGIHVVDAPVSG 122 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GAAAAAKGELA MVGAD E ++RIK F WA+++IHAG PGAGTRMKLARNMLTF SY Sbjct 123 GAAAAAKGELATMVGADREVYERIKPAFKHWAAVVIHAGGPGAGTRMKLARNMLTFTSYV 182 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 AA EA +LAEA GLDL ALG+VVRH+D+ TGG GAIM R+ ++P L HTRG Sbjct 183 AACEAMKLAEAAGLDLQALGRVVRHTDALTGGPGAIMVRDDMKDLDPGHFLYQPFLHTRG 242 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTE 290 LGEKDLSLALALG VSVDLPLA+LA + LAAGLGVPH + E Sbjct 243 LGEKDLSLALALGGAVSVDLPLARLAYEGLAAGLGVPHTEKE 284 >gi|111021633|ref|YP_704605.1| 2-hydroxy-3-oxopropionate reductase [Rhodococcus jostii RHA1] gi|110821163|gb|ABG96447.1| probable 2-hydroxy-3-oxopropionate reductase [Rhodococcus jostii RHA1] Length=291 Score = 330 bits (845), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 168/280 (60%), Positives = 214/280 (77%), Gaps = 4/280 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-AD 64 E +GYIGLGN GAPMAKRLLD PGGL V D R EA+ PF + GA +S +VAE AD Sbjct 5 EQVSVGYIGLGNMGAPMAKRLLDRPGGLIVCDTRPEALEPFGKAGARVTSSPREVAENAD 64 Query 65 IISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDA 124 +IS+TV +D QV +V+T + A+PGT+VA+HSTI+D TAV+LA++ + G+ ++DA Sbjct 65 VISVTVLNDEQVRAVVTQ---ILDTARPGTVVAVHSTISDVTAVELADRCRAHGVDLIDA 121 Query 125 PVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTF 184 PVSGGA A +G+LAVMVGA D+AF++++EPF WA L++HAG+ GAGTRMKLARN+L F Sbjct 122 PVSGGAPGALEGKLAVMVGASDDAFEKVREPFGHWAELVVHAGDVGAGTRMKLARNLLHF 181 Query 185 VSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLE 244 +S+ AAAEAQRLAEA GLD+ LGKVVRH+D+ TGGAGAIM R+TT ++ D P++ Sbjct 182 ISFTAAAEAQRLAEAAGLDITELGKVVRHTDAITGGAGAIMLRDTTDALDETDNWYPIMT 241 Query 245 HTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 H R LGEKDLSLA+ LGE + V LPLA+LAL L GLGV Sbjct 242 HVRDLGEKDLSLAIGLGERLDVALPLARLALTGLGPGLGV 281 >gi|226364169|ref|YP_002781951.1| oxidoreductase [Rhodococcus opacus B4] gi|226242658|dbj|BAH53006.1| putative oxidoreductase [Rhodococcus opacus B4] Length=291 Score = 325 bits (834), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 168/280 (60%), Positives = 211/280 (76%), Gaps = 4/280 (1%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-AD 64 E +GYIGLGN GAPMAKRLL PGGL V D R EA+ PF GA +S +VAE AD Sbjct 5 EQVSVGYIGLGNMGAPMAKRLLGRPGGLIVCDTRPEALEPFGRAGAKVTSSPREVAENAD 64 Query 65 IISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDA 124 +IS+TV +D QV +V+T + A+PGT+VA+HSTI+D TAV+LA++ + G+ ++DA Sbjct 65 VISVTVLNDEQVRAVVTQ---ILDAARPGTVVAVHSTISDVTAVELADRCRVHGVDLIDA 121 Query 125 PVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTF 184 PVSGGA A +G+LAVMVGA D AF++++EPF WA L++HAG+ GAGTRMKLARN+L F Sbjct 122 PVSGGAPGAHQGKLAVMVGASDAAFEKVREPFEHWAELVVHAGDVGAGTRMKLARNLLHF 181 Query 185 VSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLE 244 VS+ AAAEAQRLAEA GLD+ LGKVVRH+D+ TGGAGAIM R+TT ++ D P++ Sbjct 182 VSFTAAAEAQRLAEAAGLDITELGKVVRHTDAITGGAGAIMLRDTTDALDENDNWYPIMT 241 Query 245 HTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 H R LGEKDLSLA+ LGE + V LPLA+LAL L GLGV Sbjct 242 HVRDLGEKDLSLAIGLGERLDVALPLARLALTGLGPGLGV 281 >gi|319950418|ref|ZP_08024334.1| 6-phosphogluconate dehydrogenase [Dietzia cinnamea P4] gi|319435934|gb|EFV91138.1| 6-phosphogluconate dehydrogenase [Dietzia cinnamea P4] Length=343 Score = 316 bits (810), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 162/276 (59%), Positives = 203/276 (74%), Gaps = 1/276 (0%) Query 10 LGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADIISI 68 +G+IGLGN GAP+AKRLL WPGGL V DVR EA PFV GATA A+ ++VA A ++S+ Sbjct 40 VGFIGLGNMGAPIAKRLLAWPGGLVVCDVRAEATEPFVAEGATAVATGAEVARTARLVSV 99 Query 69 TVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128 TV DDAQV V+ +G+ A PGT++A+HSTI+D+TAV+LAE G+H+VDAPVSG Sbjct 100 TVLDDAQVREVVDGPDGILRTAAPGTVIAVHSTISDSTAVELAELCAASGVHLVDAPVSG 159 Query 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188 GA A G+LAVMVG E ++ K F WA + +HAGE GAGTRMKLARN+L F+S+ Sbjct 160 GAQGAESGQLAVMVGGPREVYEACKPAFGLWAGMPVHAGEVGAGTRMKLARNLLHFISFT 219 Query 189 AAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG 248 A AEA RLAEA G+D+ LG+VVRH+D+ TGGAGA+M R TTAP+ P D + H R Sbjct 220 ATAEASRLAEAAGIDIAKLGRVVRHTDAITGGAGAVMLRETTAPIAPDDFWHGVFTHVRA 279 Query 249 LGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 LGEKDLSLALALG+ + VDLPL +AL+ L +G GV Sbjct 280 LGEKDLSLALALGDRLGVDLPLGDIALRDLGSGFGV 315 >gi|54026634|ref|YP_120876.1| putative oxidoreductase [Nocardia farcinica IFM 10152] gi|54018142|dbj|BAD59512.1| putative oxidoreductase [Nocardia farcinica IFM 10152] Length=292 Score = 316 bits (809), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 170/277 (62%), Positives = 211/277 (77%), Gaps = 1/277 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADIIS 67 R+G+IGLGN GAPMA+RLL WPGGLTV D R EA+APF + GA AA S + VAE A+I+S Sbjct 5 RVGFIGLGNMGAPMAQRLLAWPGGLTVCDTRAEAVAPFTDAGAEAADSAAAVAERAEIVS 64 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V DDAQV +V+T +G+ + A+PGT++A+H+TIAD+TA DLA + + +VDAPVS Sbjct 65 VAVLDDAQVRAVVTGPDGVLSTARPGTVIAVHATIADSTAEDLAAVCAEREVALVDAPVS 124 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA A G LAVMVG + AF+R++EPF +A L++HAG GAGTRMKLARN+L FV++ Sbjct 125 GGAPGANSGRLAVMVGGTETAFERVREPFGCFADLVVHAGPVGAGTRMKLARNLLHFVAF 184 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTR 247 AA EAQRLAEA GLD+ ALGKVVRHSD+ TGG GAIM R T P+ D P+L H R Sbjct 185 TAATEAQRLAEAAGLDITALGKVVRHSDAVTGGPGAIMLRERTGPIADGDFWSPILAHVR 244 Query 248 GLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 LGEKDL LAL LGE + +DLPLA+LAL+ L AGLGV Sbjct 245 DLGEKDLGLALGLGERLGLDLPLARLALRDLGAGLGV 281 >gi|226306871|ref|YP_002766831.1| oxidoreductase [Rhodococcus erythropolis PR4] gi|226185988|dbj|BAH34092.1| putative oxidoreductase [Rhodococcus erythropolis PR4] Length=314 Score = 314 bits (805), Expect = 8e-84, Method: Compositional matrix adjust. Identities = 161/255 (64%), Positives = 201/255 (79%), Gaps = 1/255 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVA-EADIIS 67 RLGYIGLGN GAPMA+RLLDWPGGL V D R EA+ PF GA+AA++ +DVA +A IIS Sbjct 14 RLGYIGLGNMGAPMAQRLLDWPGGLMVCDARAEALEPFTTAGASAASTPADVAAQASIIS 73 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 +TV DDAQV V+ +G+ + A+PGT+VAIHSTI+DTTAV+LA+ + +G+ +VDAP+S Sbjct 74 VTVLDDAQVREVVCGPHGILSTAQPGTVVAIHSTISDTTAVELADICQQRGVLLVDAPIS 133 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA AA+G LAVM+G DEAF+ ++EPF WA L++HAG+ GAGTRMKLARN+L FVS+ Sbjct 134 GGAGGAAQGRLAVMIGGSDEAFEAVREPFGSWAELVVHAGDVGAGTRMKLARNLLHFVSF 193 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTR 247 A EA RLAEA GLDL LGKVVRH+D+ TGGAGAIM R+TTAP+ DP +L H R Sbjct 194 TATTEAARLAEAAGLDLRTLGKVVRHTDAITGGAGAIMLRDTTAPVSEDDPWFSILRHVR 253 Query 248 GLGEKDLSLALALGE 262 LGEKDL+LA+ LG+ Sbjct 254 NLGEKDLALAIDLGD 268 >gi|312138808|ref|YP_004006144.1| 6-phosphogluconate dehydrogenase [Rhodococcus equi 103S] gi|311888147|emb|CBH47459.1| putative 6-phosphogluconate dehydrogenase [Rhodococcus equi 103S] Length=298 Score = 314 bits (805), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 162/279 (59%), Positives = 204/279 (74%), Gaps = 1/279 (0%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T +GYIGLGN GAPMA RLL+ PG L V D R EA+ PF GATA ++ + VA+ A + Sbjct 5 TRAVGYIGLGNMGAPMATRLLERPGTLVVCDARAEAVEPFTTAGATAVSTPAQVADRASV 64 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 IS+TV DD QV V+ +G+ + A+PGT++A+HSTI+DTTA +LA + +G+ ++DAP Sbjct 65 ISVTVLDDGQVRDVVAGPDGILSTARPGTVIAVHSTISDTTATELAATCRAKGVDLIDAP 124 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGA A +G LAVMVG DEAF+ ++EPF +A L++HAG GAGTRMKLARN+L FV Sbjct 125 VSGGAPGAQQGRLAVMVGGSDEAFEAVREPFGYFAELVVHAGPVGAGTRMKLARNLLHFV 184 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 S+ AA EA RLAEA G+D+ LGKVVRH+D+ TGGAGAIM R+TTAP+ DP +L H Sbjct 185 SFTAACEAARLAEAAGIDIRKLGKVVRHTDAITGGAGAIMLRDTTAPVADDDPWFSILSH 244 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 R LGEKDL+LAL LG+ VDLPL AL L GLGV Sbjct 245 VRNLGEKDLALALDLGDRFDVDLPLGARALAGLGPGLGV 283 >gi|343927853|ref|ZP_08767321.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433] gi|343762494|dbj|GAA14247.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433] Length=293 Score = 312 bits (800), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 164/290 (57%), Positives = 212/290 (74%), Gaps = 3/290 (1%) Query 6 ETP-RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEA- 63 ETP RLGY+GLGN G PMA L WPGGLTVFD+ EA+A V+ GA AA S++++A A Sbjct 4 ETPIRLGYVGLGNIGGPMAGSLAAWPGGLTVFDLSEEAIAKVVDKGAKAAGSLAELASAA 63 Query 64 DIISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVD 123 DII I V +D QV SV+T +GL + A+PGTI+ +HSTI TA+DLA++ + + ++D Sbjct 64 DIIGICVLNDEQVRSVVTGADGLLSTARPGTIITVHSTIGPDTAIDLAKQCAERDVILLD 123 Query 124 APVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAG-EPGAGTRMKLARNML 182 AP+SGGA AA G LA+MVG +A++++KEPF + +L+HAG E GAGT+MKLARN+L Sbjct 124 APISGGAMGAASGRLAIMVGGPRDAYEKLKEPFRLTSDMLVHAGAEVGAGTKMKLARNLL 183 Query 183 TFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPL 242 F+S+ A EA RLAEA GLD+ LG+VVRH+D+ TGGAGAIM R TTA ++ DP + Sbjct 184 HFISFTATTEAARLAEAAGLDITKLGRVVRHTDAITGGAGAIMLRETTATLDADDPWYGI 243 Query 243 LEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPHPDTEPA 292 R LGEKDLSLALAL + + VDLPL Q+AL+ LA GLGVPH + E A Sbjct 244 FTGVRTLGEKDLSLALALADDLGVDLPLGQIALRELAPGLGVPHLEGETA 293 >gi|325676492|ref|ZP_08156170.1| 3-hydroxyisobutyrate dehydrogenase [Rhodococcus equi ATCC 33707] gi|325552670|gb|EGD22354.1| 3-hydroxyisobutyrate dehydrogenase [Rhodococcus equi ATCC 33707] Length=298 Score = 311 bits (798), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 161/279 (58%), Positives = 204/279 (74%), Gaps = 1/279 (0%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T +GYIGLG+ GAPMA RLL+ PG L V D R EA+ PF GATA ++ + VA+ A + Sbjct 5 TRAVGYIGLGSMGAPMATRLLERPGTLVVCDARAEAVEPFTTAGATAVSTPAHVADRASV 64 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 IS+TV DD QV V+ +G+ + A+PGT++A+HSTI+DTTA +LA + +G+ ++DAP Sbjct 65 ISVTVLDDGQVRDVVAGPDGILSTARPGTVIAVHSTISDTTATELAATCRAKGVDLIDAP 124 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGGA A +G LAVMVG DEAF+ ++EPF +A L++HAG GAGTRMKLARN+L FV Sbjct 125 VSGGAPGAQQGRLAVMVGGSDEAFEAVREPFGYFAELVVHAGPVGAGTRMKLARNLLHFV 184 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 S+ AA EA RLAEA G+D+ LGKVVRH+D+ TGGAGAIM R+TTAP+ DP +L H Sbjct 185 SFTAACEAARLAEAAGIDIRKLGKVVRHTDAITGGAGAIMLRDTTAPVADDDPWFSILSH 244 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV 284 R LGEKDL+LAL LG+ VDLPL AL L GLGV Sbjct 245 VRNLGEKDLALALDLGDRFDVDLPLGARALAGLGPGLGV 283 >gi|262203712|ref|YP_003274920.1| 3-hydroxyisobutyrate dehydrogenase [Gordonia bronchialis DSM 43247] gi|262087059|gb|ACY23027.1| 3-hydroxyisobutyrate dehydrogenase [Gordonia bronchialis DSM 43247] Length=291 Score = 309 bits (791), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 158/280 (57%), Positives = 205/280 (74%), Gaps = 2/280 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV-AEADIIS 67 RLGY+GLGN G PMA RL WPGGL+VFD+ +A+A V+ GA AA S++D+ + ADII Sbjct 5 RLGYVGLGNIGGPMAARLAKWPGGLSVFDLAPQAVATLVDQGAGAAQSLADLGSRADIIG 64 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 I V DD QV +V+ D GL + A PGTI+ +HSTI+ TA +LA+ G+ ++DAP+S Sbjct 65 ICVVDDDQVRTVVAGDGGLLSTAAPGTIITVHSTISPDTATELAQTCAASGVVLLDAPIS 124 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAG-EPGAGTRMKLARNMLTFVS 186 GGA A +G LA+MVG D +++ RIKEPF+ A +++HAG + GAGT+MKLARN+L F+S Sbjct 125 GGAPGAEQGRLAIMVGGDRDSYTRIKEPFALTADMIVHAGNDVGAGTKMKLARNLLHFIS 184 Query 187 YAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHT 246 + A EA RLAEA G+D+ LGKVVRH+D+ TGGAGAIM R+TTAP++P D + H Sbjct 185 FTATTEAARLAEAAGIDIAKLGKVVRHTDAITGGAGAIMLRDTTAPIDPDDFWYGIFTHV 244 Query 247 RGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 R LGEKDL LAL L E + VDLPL Q+AL+ LA GLGV H Sbjct 245 RTLGEKDLGLALGLAEQLGVDLPLGQIALRDLADGLGVGH 284 >gi|229492750|ref|ZP_04386551.1| hypothetical oxidoreductase [Rhodococcus erythropolis SK121] gi|229320409|gb|EEN86229.1| hypothetical oxidoreductase [Rhodococcus erythropolis SK121] Length=311 Score = 303 bits (776), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 161/255 (64%), Positives = 200/255 (79%), Gaps = 1/255 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVA-EADIIS 67 RLGYIGLGN GAPMA+RLLDWPGGL V D R EA+ PF GA+AA++ +DVA +A IIS Sbjct 14 RLGYIGLGNMGAPMAQRLLDWPGGLVVCDARAEALEPFTAAGASAASTPADVAAQASIIS 73 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 +TV DDAQV V+ +G+ + A+PGT+VAIHSTI+DTTAV+LA+ + +G+ +VDAP+S Sbjct 74 VTVLDDAQVREVVCGPHGILSTAQPGTVVAIHSTISDTTAVELADICQQRGVLLVDAPIS 133 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA AA+G LAVM+G DEAF ++EPF WA L++HAG+ GAGTRMKLARN+L FVS+ Sbjct 134 GGAGGAAQGRLAVMIGGSDEAFGAVREPFGSWAELVVHAGDVGAGTRMKLARNLLHFVSF 193 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTR 247 A EA RLAEA GLDL LGKVVRH+D+ TGGAGAIM R+TTAP+ DP +L H R Sbjct 194 TATTEAARLAEAAGLDLRTLGKVVRHTDAITGGAGAIMLRDTTAPVSEDDPWFSILRHVR 253 Query 248 GLGEKDLSLALALGE 262 LGEKDL+LA+ LG+ Sbjct 254 NLGEKDLALAIDLGD 268 >gi|326384244|ref|ZP_08205926.1| 3-hydroxyisobutyrate dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326197109|gb|EGD54301.1| 3-hydroxyisobutyrate dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=296 Score = 254 bits (650), Expect = 9e-66, Method: Compositional matrix adjust. Identities = 147/283 (52%), Positives = 189/283 (67%), Gaps = 6/283 (2%) Query 6 ETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVA-EAD 64 T RLGYIGLGN G PMA RL +T FDV +A+A V+ GATAA S++ +A D Sbjct 4 NTLRLGYIGLGNIGGPMAARLAAAAP-MTAFDVSPDALAAVVDAGATAADSLAGLATSCD 62 Query 65 IISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDA 124 +ISI V DD QV V+ GL H PG+++A+HSTI+ TA + AE + ++DA Sbjct 63 LISICVRDDDQVREVV---GGLLDHLAPGSLIAVHSTISPETAAEQAELCARHDVVLLDA 119 Query 125 PVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAG-EPGAGTRMKLARNMLT 183 P+SGGA A +G LA+M+G D A+ R K + +++HAG G GTRMKLARN+L Sbjct 120 PISGGAPGAKEGRLAIMIGGDRAAYDRAKAALAPAGDMIVHAGPNAGDGTRMKLARNLLH 179 Query 184 FVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLL 243 F+S+ A EA RLAEA G+D+ LG+VVRH+D+ TGGAGAIM R+TTAP+ P D + Sbjct 180 FISFTATTEAARLAEAAGIDIAKLGRVVRHTDAITGGAGAIMLRDTTAPIAPDDFWYGVF 239 Query 244 EHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVPH 286 H R LGEKDL+LAL L + + VDLPL + AL LAAGLGVPH Sbjct 240 THVRELGEKDLTLALGLADELGVDLPLGRRALTDLAAGLGVPH 282 >gi|326331684|ref|ZP_08197972.1| 3-hydroxyisobutyrate dehydrogenase family protein [Nocardioidaceae bacterium Broad-1] gi|325950483|gb|EGD42535.1| 3-hydroxyisobutyrate dehydrogenase family protein [Nocardioidaceae bacterium Broad-1] Length=277 Score = 218 bits (554), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 134/276 (49%), Positives = 179/276 (65%), Gaps = 4/276 (1%) Query 13 IGLGNQGAPMAKRLLDWPG-GLTVFDVRVEAMAPFVEGGATAAASVSDVAEA-DIISITV 70 +GLGN G PMA RL G L V D+ E +A GA AASV ++A A D++S+ V Sbjct 1 MGLGNIGRPMALRLAGADGIELWVHDIAAEPVAELGAAGAKTAASVGELASAVDVLSVMV 60 Query 71 FDDAQVSSVITADNGLATHAKPGTI-VAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGG 129 DD QV VI A+ A + G + V +HST+A T LA P G+ ++DAPVSGG Sbjct 61 RDDEQVRQVI-AEVIAADRSTQGPLTVLVHSTVAPETPAALATTAGPHGVQVLDAPVSGG 119 Query 130 AAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAA 189 AA+G LA++VG EA+ + + ++HAG GAGT++KLARN+L F S+ A Sbjct 120 PMGAAEGTLAILVGGTPEAYAAAAPVLAAMGTKVVHAGPVGAGTKLKLARNLLHFASFTA 179 Query 190 AAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRGL 249 A EA RLAEA GLDL ALG+VVRH+D+ TGG GA+++R+TTAP+E D + H L Sbjct 180 ATEAARLAEAAGLDLKALGEVVRHTDAITGGPGAVLYRDTTAPIEETDFWHGVFGHVAAL 239 Query 250 GEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGVP 285 GEKDL A+AL + + V++PLA+LAL+RLA GLG+P Sbjct 240 GEKDLGFAIALADELGVEVPLARLALERLAPGLGLP 275 >gi|254481193|ref|ZP_05094438.1| hypothetical protein GPB2148_1666 [marine gamma proteobacterium HTCC2148] gi|214038356|gb|EEB79018.1| hypothetical protein GPB2148_1666 [marine gamma proteobacterium HTCC2148] Length=291 Score = 149 bits (377), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 97/278 (35%), Positives = 143/278 (52%), Gaps = 14/278 (5%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADI-IS 67 +G+IGLG+ G PMA RL+ L V+D+ + VE GA A SV++VA + I Sbjct 5 NVGFIGLGDIGKPMATRLISEAFKLHVYDLLQPVVDELVEQGAEACQSVAEVAAQCMHIG 64 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 I V DD QV +++ G+ +A GT++A+HST+ + + AE G++++DAP++ Sbjct 65 ICVRDDRQVEALLYGAEGILANAANGTVIAVHSTVTQSKLLQWAEDAHHSGLYLLDAPIT 124 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA AA G L MVG D+ R + F+ A ++HAG+ GAG +KL N + + + Sbjct 125 GGARRAADGTLCYMVGGDEAVIDRCRSIFATSAEKVVHAGDLGAGIALKLCNNFIQYAEF 184 Query 188 AAAAEAQRLAEACGLDLVAL-------GKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLR 240 A AEA RLAEA GL + L G + F G + + M AD Sbjct 185 VAMAEATRLAEASGLSVDVLREVGLSNGVINEQMHLFVSGRNNLALSCSEEQM--ADIFG 242 Query 241 PLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRL 278 PL LG+KDL L + LP A+ +R+ Sbjct 243 PL----GALGQKDLQCVLDSAGDHGIALPTAEFLRERI 276 >gi|333992135|ref|YP_004524749.1| 3-hydroxyisobutyrate dehydrogenase MmsB [Mycobacterium sp. JDM601] gi|333488103|gb|AEF37495.1| 3-hydroxyisobutyrate dehydrogenase MmsB [Mycobacterium sp. JDM601] Length=272 Score = 135 bits (339), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 81/212 (39%), Positives = 118/212 (56%), Gaps = 3/212 (1%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEA-DIIS 67 R+G+IGLG+QGAPMA+R+++ T++ R + F + A A S +D+ A D++ Sbjct 2 RVGFIGLGSQGAPMARRIIEGGYSTTLWARRAATLEAFADTEARVADSPADLGHASDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V DA V V+ +NG+ + G ++AIHST+ T LAE QG+ ++DAPVS Sbjct 62 LCVVGDADVEQVVQGENGVLAGMQRGGVIAIHSTVHPDTCRRLAEHCARQGVSLIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG AA G L VM G D+E QR + F +A ++H G G+G KL N+L + Sbjct 122 GGGPAAEAGTLLVMAGGDEEVVQRCRPVFDTYADPVVHLGGLGSGQVTKLLNNLLFTANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRH--SDSF 217 AA A L E G+ L +VV S+SF Sbjct 182 GTAATALALGEQLGVSRERLAEVVSRGSSNSF 213 >gi|108800659|ref|YP_640856.1| 6-phosphogluconate dehydrogenase protein [Mycobacterium sp. MCS] gi|119869798|ref|YP_939750.1| 6-phosphogluconate dehydrogenase [Mycobacterium sp. KMS] gi|108771078|gb|ABG09800.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. MCS] gi|119695887|gb|ABL92960.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. KMS] Length=272 Score = 132 bits (333), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 76/229 (34%), Positives = 129/229 (57%), Gaps = 2/229 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEA-DIIS 67 R+G+IGLG+QG PMA+R+++ LT++ R ++ P+ + A A S +++A A D++ Sbjct 2 RVGFIGLGSQGGPMARRIVEGGYELTLWARRPASLEPYADTAAKTAGSPAELAAASDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V D V V+ D G+ PG ++AIHST+ T ++AEK Q + ++DAPVS Sbjct 62 VCVVGDDDVREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA A +G+L VMVG ++ ++ + F+ +A ++H G G+G K+ N+L + Sbjct 122 GGAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLFTANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAI-MFRNTTAPMEP 235 +A L E+ G+ L +V+ + + G+I MF T + P Sbjct 182 GSALSTLELGESLGIPRTQLAEVLNGGSATSKALGSISMFGGTVEALAP 230 >gi|118470062|ref|YP_889072.1| 6-phosphogluconate dehydrogenase, NAD-binding [Mycobacterium smegmatis str. MC2 155] gi|118171349|gb|ABK72245.1| 6-phosphogluconate dehydrogenase, NAD-binding [Mycobacterium smegmatis str. MC2 155] Length=272 Score = 131 bits (330), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/229 (35%), Positives = 130/229 (57%), Gaps = 2/229 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEA-DIIS 67 R+G+IGLG+QGAPMA+R+++ T++ R ++ PF + A A + +++A A D++ Sbjct 2 RVGFIGLGSQGAPMARRIVEGGFETTLWARRPASLEPFADTAAKVAGTPAELAAASDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V D V V+ + G+ PG I+AIHST+ T ++AE++ +GI ++DAPVS Sbjct 62 LCVVGDDDVREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG AA G L VM G D++ +++ F+ +A ++ G G+G K+ N+L + Sbjct 122 GGEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLLFSANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAI-MFRNTTAPMEP 235 AA A L EA G+ AL +V+ + + G+I MF T + P Sbjct 182 GAAMSALELGEALGVPRSALCEVITRGSANSKALGSIAMFGGTLDNLAP 230 >gi|120405127|ref|YP_954956.1| 6-phosphogluconate dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119957945|gb|ABM14950.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium vanbaalenii PYR-1] Length=272 Score = 130 bits (328), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 78/229 (35%), Positives = 127/229 (56%), Gaps = 2/229 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV-AEADIIS 67 R+G+IGLG+QG PMA+R+ + T++ R ++ P+ + A AA+ +++ A +D++ Sbjct 2 RVGFIGLGSQGGPMARRIAEGGFETTLWARRPASLEPYADTPAKTAATPAELGANSDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V D V V+ ++G+ G I+AIHST+ T ++AEK QGI ++DAPVS Sbjct 62 LCVVGDDDVREVLYGESGVLAGLAEGGIIAIHSTVHPDTCREIAEKSAAQGISVIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG A +G L VMVG D+E QR + F+ +A ++H G G+G K+ N+L + Sbjct 122 GGGPAVEQGTLLVMVGGDEEVAQRCRPVFATYADPIVHLGPLGSGQNTKILNNLLFSANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAI-MFRNTTAPMEP 235 AA L E+ G+ L +V+ + + +I MF T + P Sbjct 182 GAAVSTLELGESLGIPRQKLVEVLNRGSATSKAVASISMFGGTLEGLAP 230 >gi|126436283|ref|YP_001071974.1| 6-phosphogluconate dehydrogenase [Mycobacterium sp. JLS] gi|126236083|gb|ABN99483.1| 6-phosphogluconate dehydrogenase, NAD-binding protein [Mycobacterium sp. JLS] Length=272 Score = 129 bits (325), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 74/229 (33%), Positives = 128/229 (56%), Gaps = 2/229 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEA-DIIS 67 R+G+IGLG+QG PMA+R+++ LT++ R ++ P+ + A A + +++A A D++ Sbjct 2 RVGFIGLGSQGGPMARRIVEGGYELTLWARRPASLEPYADTAAKTAGTPAELAAASDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V D V V+ D G+ PG ++AIHST+ T ++AEK + ++DAPVS Sbjct 62 VCVVGDDDVREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAHSVSVIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GGA A +G+L VMVG ++ ++ + F+ +A ++H G G+G K+ N+L + Sbjct 122 GGAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLFTANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAI-MFRNTTAPMEP 235 +A L E+ G+ L +V+ + + G+I MF T + P Sbjct 182 GSALSTLELGESLGIPRTQLAEVLNGGSATSKALGSISMFGGTVEALAP 230 >gi|220935102|ref|YP_002514001.1| oxidoreductase [Thioalkalivibrio sulfidophilus HL-EbGr7] gi|219996412|gb|ACL73014.1| oxidoreductase protein [Thioalkalivibrio sulfidophilus HL-EbGr7] Length=290 Score = 128 bits (321), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 79/196 (41%), Positives = 109/196 (56%), Gaps = 1/196 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVA-EADIIS 67 ++GYIGLG G PMA LL + V+ R E++ P GAT AAS +++A + D++ Sbjct 2 KVGYIGLGIMGRPMAANLLKAGYEVCVWARRPESLEPLKAAGATVAASPAELAGQVDVVF 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 V D A V +V+ +NG+ A+PG IV HSTIA + +AEKL QGI ++D PVS Sbjct 62 TNVSDTADVEAVLLGENGVIHGARPGLIVVDHSTIAAGASRRMAEKLAGQGIQMLDVPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG A G L +MVG + EA ++++ + H G PGAG K M+ S Sbjct 122 GGEQGAIDGTLTLMVGGEAEALEKVRPLLEVVGGTITHVGGPGAGQIAKTCNQMIVAQSL 181 Query 188 AAAAEAQRLAEACGLD 203 A EA LAEA +D Sbjct 182 QAIGEAFTLAEAADVD 197 >gi|332981071|ref|YP_004462512.1| tartronate semialdehyde reductase [Mahella australiensis 50-1 BON] gi|332698749|gb|AEE95690.1| tartronate semialdehyde reductase [Mahella australiensis 50-1 BON] Length=295 Score = 127 bits (320), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 91/273 (34%), Positives = 137/273 (51%), Gaps = 13/273 (4%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 ++G+IGLG G PMAK LL + +D+ E + V GA A+S +VAE I I Sbjct 2 KIGFIGLGIMGKPMAKNLLKAGHEVVGYDIVKENVDNVVAAGAKPASSAKEVAEQCSIII 61 Query 69 TVFDDA-QVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 T+ ++ V V+ +NG+ AKPGTI+ S+IA + ++ + + +G+ ++DAPVS Sbjct 62 TMLPNSPHVKEVVMGENGILEGAKPGTILIDMSSIAPLASQEICKACEAKGVKMIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG A G L++MVG D F+++ + S +H G+ GAG KLA ++ ++ Sbjct 122 GGEPKAIDGTLSIMVGGDKAVFEQVYDILMVMGSSAVHCGDIGAGNTTKLANQVIVALNI 181 Query 188 AAAAEAQRLAEACGLD--LVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 AA +EA LA G+D LV D+ GG N APM P + Sbjct 182 AAVSEAFMLATKAGVDPQLV--------FDAIKGGLAGSTVMNAKAPMIMEGNFEPGFK- 232 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRL 278 L KDL+ L G V LPL ++ + Sbjct 233 -IDLHIKDLNNVLETGHSVGSPLPLTAAVMEMM 264 >gi|150390719|ref|YP_001320768.1| tartronate semialdehyde reductase [Alkaliphilus metalliredigens QYMF] gi|149950581|gb|ABR49109.1| 2-hydroxy-3-oxopropionate reductase [Alkaliphilus metalliredigens QYMF] Length=295 Score = 127 bits (320), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 91/269 (34%), Positives = 137/269 (51%), Gaps = 17/269 (6%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISI 68 ++G+IGLG G PMAK LL +T+F R E E GA +S DVA+ + I Sbjct 3 KIGFIGLGVMGKPMAKNLLKAGYRVTIFANRKEVQQELAEAGAEVGSSAKDVAQKTEVII 62 Query 69 TVFDDA-QVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 T+ ++ V VI +G+ A+ G I+ S+IA + ++A+KLK +G+ ++DAPVS Sbjct 63 TMLPNSPDVKQVILGKDGVLEGAREGMIIIDMSSIAPLASQEIAKKLKEKGVEMLDAPVS 122 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG A A G LA+M+G + F+R+K+ + S ++ GE G+G KLA ++ ++ Sbjct 123 GGEAKAIDGTLAIMLGGPEAVFERVKDILAVMGSSVVRVGEIGSGNVTKLANQIIVALNI 182 Query 188 AAAAEAQRLAEACGLD----LVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLL 243 AA +EA LA G+D A+G GG+ + P A +P Sbjct 183 AAMSEAMVLATKAGVDPENVFQAIG----------GGSAGSSVLDKKFPRIKAGDFKPGF 232 Query 244 EHTRGLGEKDLSLALALGEVVSVDLPLAQ 272 L KDL AL G+ + V LPL Sbjct 233 RLE--LHIKDLLNALDTGDEIDVPLPLTN 259 >gi|336247317|ref|YP_004591027.1| tartronate semialdehyde reductase [Enterobacter aerogenes KCTC 2190] gi|334733373|gb|AEG95748.1| tartronate semialdehyde reductase [Enterobacter aerogenes KCTC 2190] Length=296 Score = 127 bits (319), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 97/282 (35%), Positives = 141/282 (50%), Gaps = 13/282 (4%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 2 TIKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDV 61 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT+V S+IA + +++E LK +GI ++DAP Sbjct 62 IITMLPNSPHVKDVALGENGIIEGAKPGTVVIDMSSIAPLASREISEALKAKGIDMLDAP 121 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 122 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVAL 181 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P Sbjct 182 NIAAMSEALTLATKAGVNPELVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGFRI 235 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA----GLG 283 L KDL+ AL V LPL ++ + A GLG Sbjct 236 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLG 275 >gi|315443525|ref|YP_004076404.1| beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase [Mycobacterium sp. Spyr1] gi|315261828|gb|ADT98569.1| beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase [Mycobacterium sp. Spyr1] Length=272 Score = 126 bits (316), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 74/229 (33%), Positives = 126/229 (56%), Gaps = 2/229 (0%) Query 9 RLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDV-AEADIIS 67 R+G+IGLG+QG PMA+R+ + T++ R ++ P+ + A A++ +++ A +D++ Sbjct 2 RVGFIGLGSQGGPMARRIAEGGFETTLWARRQASLEPYSDTPAKTASTPAELGAASDLVC 61 Query 68 ITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVS 127 + V D V V+ + G+ G I+AIHST+ T ++AEK QG+ ++DAPVS Sbjct 62 LCVVGDDDVREVLYGEQGVLAGLAEGGIIAIHSTVHPQTCQEIAEKAAAQGVSVIDAPVS 121 Query 128 GGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSY 187 GG A +G L VMVG D+E +R + F+ +A ++H G G+G K+ N+L + Sbjct 122 GGGPAVEQGTLLVMVGGDEEVAERCRPVFATYADPIVHLGPLGSGQNTKILNNLLFSANL 181 Query 188 AAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAI-MFRNTTAPMEP 235 +A L E+ G+ L +V+ + + +I MF T + P Sbjct 182 GSAVSTLELGESLGIPRAKLVEVLSKGSATSKAVSSISMFGGTLDGLAP 230 >gi|117625425|ref|YP_858748.1| tartronate semialdehyde reductase [Escherichia coli APEC O1] gi|237706121|ref|ZP_04536602.1| tartronate semialdehyde reductase [Escherichia sp. 3_2_53FAA] gi|91074121|gb|ABE09002.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli UTI89] gi|115514549|gb|ABJ02624.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli APEC O1] gi|226899161|gb|EEH85420.1| tartronate semialdehyde reductase [Escherichia sp. 3_2_53FAA] gi|315288911|gb|EFU48309.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli MS 110-3] gi|323951351|gb|EGB47226.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli H252] gi|323957722|gb|EGB53436.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli H263] Length=299 Score = 125 bits (315), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 96/283 (34%), Positives = 142/283 (51%), Gaps = 13/283 (4%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 5 TMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDV 64 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT++ S+IA + +++E LK +GI ++DAP Sbjct 65 IITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAP 124 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 125 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVAL 184 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P Sbjct 185 NIAAMSEALTLATKAGVNPDLVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGFRI 238 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA----GLGV 284 L KDL+ AL V LPL ++ + A GLG+ Sbjct 239 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGM 279 >gi|170766167|ref|ZP_02900978.1| 2-hydroxy-3-oxopropionate reductase [Escherichia albertii TW07627] gi|170125313|gb|EDS94244.1| 2-hydroxy-3-oxopropionate reductase [Escherichia albertii TW07627] Length=299 Score = 125 bits (315), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 93/275 (34%), Positives = 139/275 (51%), Gaps = 9/275 (3%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 5 TMKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIAEVIAAGAETASTAKAIAEQCDV 64 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT++ S+IA + +++E LK +GI ++DAP Sbjct 65 IITMLPNSPHVKEVALGENGIIDGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAP 124 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 125 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKSMAGSVVHTGEIGAGNVTKLANQVIVAL 184 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P + Sbjct 185 NIAAMSEALTLAAKAGVNPDLVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGVRI 238 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA 280 L KDL+ AL V LPL ++ + A Sbjct 239 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQA 271 >gi|162138369|ref|YP_542533.2| tartronate semialdehyde reductase [Escherichia coli UTI89] gi|218560201|ref|YP_002393114.1| tartronate semialdehyde reductase [Escherichia coli S88] gi|218366970|emb|CAR04741.1| tartronate semialdehyde reductase [Escherichia coli S88] gi|307625270|gb|ADN69574.1| tartronate semialdehyde reductase [Escherichia coli UM146] Length=296 Score = 125 bits (315), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 96/283 (34%), Positives = 142/283 (51%), Gaps = 13/283 (4%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 2 TMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDV 61 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT++ S+IA + +++E LK +GI ++DAP Sbjct 62 IITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAP 121 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 122 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVAL 181 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P Sbjct 182 NIAAMSEALTLATKAGVNPDLVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGFRI 235 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA----GLGV 284 L KDL+ AL V LPL ++ + A GLG+ Sbjct 236 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGM 276 >gi|312968534|ref|ZP_07782743.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli 2362-75] gi|312286752|gb|EFR14663.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli 2362-75] Length=296 Score = 125 bits (315), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 96/282 (35%), Positives = 141/282 (50%), Gaps = 13/282 (4%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 2 TMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDV 61 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT++ S+IA + +++E LK +GI ++DAP Sbjct 62 IITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAP 121 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 122 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVAL 181 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P Sbjct 182 NIAAMSEALTLATKAGVNPDLVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGFRI 235 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA----GLG 283 L KDL+ AL V LPL ++ + A GLG Sbjct 236 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLG 275 >gi|300897878|ref|ZP_07116261.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli MS 198-1] gi|300358392|gb|EFJ74262.1| 2-hydroxy-3-oxopropionate reductase [Escherichia coli MS 198-1] Length=299 Score = 125 bits (315), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 96/282 (35%), Positives = 141/282 (50%), Gaps = 13/282 (4%) Query 7 TPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAE-ADI 65 T ++G+IGLG G PM+K LL L V D EA+A + GA A++ +AE D+ Sbjct 5 TMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDV 64 Query 66 ISITVFDDAQVSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAP 125 I + + V V +NG+ AKPGT++ S+IA + +++E LK +GI ++DAP Sbjct 65 IITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAP 124 Query 126 VSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFV 185 VSGG A G L+VMVG D F + + A ++H GE GAG KLA ++ + Sbjct 125 VSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVAL 184 Query 186 SYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEH 245 + AA +EA LA G++ + + +R GG + APM +P Sbjct 185 NIAAMSEALTLATKAGVNPDLVYQAIR------GGLAGSTVLDAKAPMVMDRNFKPGFRI 238 Query 246 TRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAA----GLG 283 L KDL+ AL V LPL ++ + A GLG Sbjct 239 D--LHIKDLANALDTSHGVGAQLPLTAAVMEMMQAVRADGLG 278 Lambda K H 0.317 0.132 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 489554810128 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40