BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0777

Length=472
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607917|ref|NP_215291.1|  adenylosuccinate lyase [Mycobacteri...   941    0.0  
gi|31791965|ref|NP_854458.1|  adenylosuccinate lyase [Mycobacteri...   938    0.0  
gi|340625796|ref|YP_004744248.1|  putative adenylosuccinate lyase...   930    0.0  
gi|339293798|gb|AEJ45909.1|  adenylosuccinate lyase [Mycobacteriu...   929    0.0  
gi|308374091|ref|ZP_07667710.1|  adenylosuccinate lyase purB [Myc...   912    0.0  
gi|342862179|ref|ZP_08718821.1|  adenylosuccinate lyase [Mycobact...   827    0.0  
gi|118465496|ref|YP_879997.1|  adenylosuccinate lyase [Mycobacter...   825    0.0  
gi|336458298|gb|EGO37277.1|  adenylosuccinate lyase [Mycobacteriu...   823    0.0  
gi|254818444|ref|ZP_05223445.1|  adenylosuccinate lyase [Mycobact...   822    0.0  
gi|41406709|ref|NP_959545.1|  adenylosuccinate lyase [Mycobacteri...   822    0.0  
gi|296166475|ref|ZP_06848907.1|  adenylosuccinate lyase [Mycobact...   822    0.0  
gi|118471019|ref|YP_890074.1|  adenylosuccinate lyase [Mycobacter...   820    0.0  
gi|108801529|ref|YP_641726.1|  adenylosuccinate lyase [Mycobacter...   813    0.0  
gi|119870683|ref|YP_940635.1|  adenylosuccinate lyase [Mycobacter...   812    0.0  
gi|120406093|ref|YP_955922.1|  adenylosuccinate lyase [Mycobacter...   811    0.0  
gi|126437514|ref|YP_001073205.1|  adenylosuccinate lyase [Mycobac...   810    0.0  
gi|240172324|ref|ZP_04750983.1|  adenylosuccinate lyase [Mycobact...   810    0.0  
gi|315442644|ref|YP_004075523.1|  adenylosuccinate lyase [Mycobac...   806    0.0  
gi|145222205|ref|YP_001132883.1|  adenylosuccinate lyase [Mycobac...   806    0.0  
gi|183984884|ref|YP_001853175.1|  adenylosuccinate lyase, PurB [M...   803    0.0  
gi|118616331|ref|YP_904663.1|  adenylosuccinate lyase [Mycobacter...   802    0.0  
gi|333992227|ref|YP_004524841.1|  adenylosuccinate lyase PurB [My...   798    0.0  
gi|2076619|emb|CAB08409.1|  PurB [Mycobacterium leprae]                788    0.0  
gi|15828195|ref|NP_302458.1|  adenylosuccinate lyase [Mycobacteri...   786    0.0  
gi|169627789|ref|YP_001701438.1|  adenylosuccinate lyase [Mycobac...   758    0.0  
gi|54022526|ref|YP_116768.1|  adenylosuccinate lyase [Nocardia fa...   738    0.0  
gi|319951357|ref|ZP_08025182.1|  adenylosuccinate lyase [Dietzia ...   733    0.0  
gi|262200836|ref|YP_003272044.1|  adenylosuccinate lyase [Gordoni...   733    0.0  
gi|226304514|ref|YP_002764472.1|  adenylosuccinate lyase [Rhodoco...   733    0.0  
gi|229494458|ref|ZP_04388221.1|  adenylosuccinate lyase [Rhodococ...   731    0.0  
gi|312138253|ref|YP_004005589.1|  adenylosuccinate lyase purb [Rh...   729    0.0  
gi|325674839|ref|ZP_08154526.1|  adenylosuccinate lyase [Rhodococ...   729    0.0  
gi|226364288|ref|YP_002782070.1|  adenylosuccinate lyase [Rhodoco...   724    0.0  
gi|333918347|ref|YP_004491928.1|  adenylosuccinate lyase [Amycoli...   723    0.0  
gi|111021758|ref|YP_704730.1|  adenylosuccinate lyase [Rhodococcu...   721    0.0  
gi|343925803|ref|ZP_08765318.1|  adenylosuccinate lyase [Gordonia...   710    0.0  
gi|302533146|ref|ZP_07285488.1|  adenylosuccinate lyase [Streptom...   707    0.0  
gi|182440065|ref|YP_001827784.1|  adenylosuccinate lyase [Strepto...   706    0.0  
gi|329941565|ref|ZP_08290830.1|  adenylosuccinate lyase [Streptom...   705    0.0  
gi|326780734|ref|ZP_08239999.1|  adenylosuccinate lyase [Streptom...   705    0.0  
gi|291440988|ref|ZP_06580378.1|  adenylosuccinate lyase [Streptom...   705    0.0  
gi|254384272|ref|ZP_04999615.1|  adenylosuccinate lyase [Streptom...   703    0.0  
gi|302561897|ref|ZP_07314239.1|  adenylosuccinate lyase [Streptom...   702    0.0  
gi|239986171|ref|ZP_04706835.1|  adenylosuccinate lyase [Streptom...   700    0.0  
gi|344998290|ref|YP_004801144.1|  adenylosuccinate lyase [Strepto...   700    0.0  
gi|302549913|ref|ZP_07302255.1|  adenylosuccinate lyase [Streptom...   699    0.0  
gi|289773043|ref|ZP_06532421.1|  adenylosuccinate lyase [Streptom...   697    0.0  
gi|297195725|ref|ZP_06913123.1|  adenylosuccinate lyase [Streptom...   697    0.0  
gi|32141137|ref|NP_733528.1|  adenylosuccinate lyase [Streptomyce...   696    0.0  
gi|126348508|emb|CAJ90231.1|  putative adenylosuccino lyase [Stre...   695    0.0  


>gi|15607917|ref|NP_215291.1| adenylosuccinate lyase [Mycobacterium tuberculosis H37Rv]
 gi|15840192|ref|NP_335229.1| adenylosuccinate lyase [Mycobacterium tuberculosis CDC1551]
 gi|148660554|ref|YP_001282077.1| adenylosuccinate lyase [Mycobacterium tuberculosis H37Ra]
 54 more sequence titles
 Length=472

 Score =  941 bits (2431),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 471/472 (99%), Positives = 472/472 (100%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
Sbjct  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
Sbjct  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
Sbjct  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472


>gi|31791965|ref|NP_854458.1| adenylosuccinate lyase [Mycobacterium bovis AF2122/97]
 gi|121636701|ref|YP_976924.1| adenylosuccinate lyase [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224989173|ref|YP_002643860.1| putative adenylosuccinate lyase [Mycobacterium bovis BCG str. 
Tokyo 172]
 18 more sequence titles
 Length=472

 Score =  938 bits (2425),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 470/472 (99%), Positives = 471/472 (99%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
Sbjct  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
Sbjct  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
Sbjct  421  LPLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472


>gi|340625796|ref|YP_004744248.1| putative adenylosuccinate lyase PURB [Mycobacterium canettii 
CIPT 140010059]
 gi|340003986|emb|CCC43121.1| putative adenylosuccinate lyase PURB (adenylosuccinase) (ASL) 
(ASASE) [Mycobacterium canettii CIPT 140010059]
Length=472

 Score =  930 bits (2404),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 466/472 (99%), Positives = 468/472 (99%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAKVV+ERRLWLAVLRAQAELGVAVADSVLADYERVVD
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKVVAERRLWLAVLRAQAELGVAVADSVLADYERVVD  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
Sbjct  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA VARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
Sbjct  121  AHGVAVVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGD AALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTGQDMLDLLGGDPAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
Sbjct  421  LPLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472


>gi|339293798|gb|AEJ45909.1| adenylosuccinate lyase [Mycobacterium tuberculosis CCDC5079]
Length=472

 Score =  929 bits (2401),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/472 (99%), Positives = 469/472 (99%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
Sbjct  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
Sbjct  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASMVAELA +  NEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMVAELARSAGNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
Sbjct  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472


>gi|308374091|ref|ZP_07667710.1| adenylosuccinate lyase purB [Mycobacterium tuberculosis SUMu006]
 gi|308343039|gb|EFP31890.1| adenylosuccinate lyase purB [Mycobacterium tuberculosis SUMu006]
Length=457

 Score =  912 bits (2357),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 456/457 (99%), Positives = 457/457 (100%), Gaps = 0/457 (0%)

Query  16   MVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDVDLASISARERVLR  75
            MVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV+LASISARERVLR
Sbjct  1    MVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDVNLASISARERVLR  60

Query  76   HDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAHGVAAVARLAERAV  135
            HDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAHGVAAVARLAERAV
Sbjct  61   HDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAHGVAAVARLAERAV  120

Query  136  SYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYPLRGIKGPMGTGQD  195
            SYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYPLRGIKGPMGTGQD
Sbjct  121  SYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYPLRGIKGPMGTGQD  180

Query  196  MLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSALVQLGAGPSSLAH  255
            MLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSALVQLGAGPSSLAH
Sbjct  181  MLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSALVQLGAGPSSLAH  240

Query  256  TIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMVAELAGAQWN  315
            TIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMVAELAGAQWN
Sbjct  241  TIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMVAELAGAQWN  300

Query  316  EGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELDRYLPFLATTKVLM  375
            EGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELDRYLPFLATTKVLM
Sbjct  301  EGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELDRYLPFLATTKVLM  360

Query  376  AAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLTLGRDALEAALADK  435
            AAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLTLGRDALEAALADK
Sbjct  361  AAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLTLGRDALEAALADK  420

Query  436  KAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            KAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
Sbjct  421  KAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  457


>gi|342862179|ref|ZP_08718821.1| adenylosuccinate lyase [Mycobacterium colombiense CECT 3035]
 gi|342130257|gb|EGT83577.1| adenylosuccinate lyase [Mycobacterium colombiense CECT 3035]
Length=472

 Score =  827 bits (2137),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 420/472 (89%), Positives = 441/472 (94%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAKVV+ERRLWLAVLRAQAELGV V    +ADYERV++
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKVVAERRLWLAVLRAQAELGVPVPSDAIADYERVIE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASI+ RERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  61   DVDLASIADRERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
             HGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  121  GHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALTRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDLL GD A LADLERRVA+FLGFATV  SVGQVYPRSLDHDV+
Sbjct  181  YPLRGIKGPMGTAQDMLDLLDGDTAKLADLERRVAEFLGFATVLTSVGQVYPRSLDHDVL  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVI RE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVISRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAG+GRE+AH +I EHAVATALAMREHGAEPDLL RLAAD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGVGREAAHHVIREHAVATALAMREHGAEPDLLQRLAADER  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADKKAF GAAGDQVD+V A VDALV+RYPDAAKY PGAIL
Sbjct  421  LPLDRAALDAALADKKAFTGAAGDQVDEVAAQVDALVNRYPDAAKYAPGAIL  472


>gi|118465496|ref|YP_879997.1| adenylosuccinate lyase [Mycobacterium avium 104]
 gi|254773660|ref|ZP_05215176.1| adenylosuccinate lyase [Mycobacterium avium subsp. avium ATCC 
25291]
 gi|118166783|gb|ABK67680.1| adenylosuccinate lyase [Mycobacterium avium 104]
Length=472

 Score =  825 bits (2131),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/472 (89%), Positives = 444/472 (95%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLA RYASAEMVAIWSPEAKVV+ERRLWLAVLRAQ +LGVAV    +ADYERV++
Sbjct  1    MSIPNVLAARYASAEMVAIWSPEAKVVAERRLWLAVLRAQQQLGVAVPAEAIADYERVLE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASI+ RER+LRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  61   DVDLASIADRERLLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  121  AHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALARLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDLLGGD A LA+LERRVA+FLGF+TV  SVGQVYPRSLDHDV+
Sbjct  181  YPLRGIKGPMGTSQDMLDLLGGDPAKLAELERRVAEFLGFSTVLTSVGQVYPRSLDHDVI  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMREHGAEPDLL+RLAAD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMREHGAEPDLLERLAADER  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD++AF GAA DQVD+V A VDALVSRYPDAAKYTPGAIL
Sbjct  421  LPLDRAALDAALADRRAFTGAAADQVDEVAAQVDALVSRYPDAAKYTPGAIL  472


>gi|336458298|gb|EGO37277.1| adenylosuccinate lyase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=474

 Score =  823 bits (2126),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/472 (89%), Positives = 443/472 (94%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            VSIPNVLA RYASAEMVAIWSPEAKVV+ERRLWLAVLRAQ +LGVAV    +ADYERV++
Sbjct  3    VSIPNVLAARYASAEMVAIWSPEAKVVAERRLWLAVLRAQQQLGVAVPAEAIADYERVLE  62

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASI+ RER+LRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  63   DVDLASIADRERLLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  122

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  123  AHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALARLRELIDR  182

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL+GGD A LA+LERRVA+FLGF+ V  SVGQVYPRSLDHDVV
Sbjct  183  YPLRGIKGPMGTSQDMLDLIGGDPAKLAELERRVAEFLGFSMVLTSVGQVYPRSLDHDVV  242

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  243  SALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  302

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVIGRE
Sbjct  303  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIGRE  362

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMREHGAEPDLL+RLAAD R
Sbjct  363  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMREHGAEPDLLERLAADER  422

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD++AF GAA DQVD+V A VDALVSRYPDAAKYTPGAIL
Sbjct  423  LPLDRAALDAALADRRAFTGAAADQVDEVAAQVDALVSRYPDAAKYTPGAIL  474


>gi|254818444|ref|ZP_05223445.1| adenylosuccinate lyase [Mycobacterium intracellulare ATCC 13950]
Length=472

 Score =  822 bits (2124),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/472 (89%), Positives = 441/472 (94%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASAEMVAIWSPEAK+V+ERRLWLAVLRAQAELGVAV    +ADYERV++
Sbjct  1    MSIPNVLATRYASAEMVAIWSPEAKIVAERRLWLAVLRAQAELGVAVPPDAIADYERVLE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDL+SI+ RERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  61   DVDLSSIADRERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  121  AHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALTRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDLL GD A LA+LERR+A FLGFATV  SVGQVYPRSLDHDV+
Sbjct  181  YPLRGIKGPMGTSQDMLDLLDGDAAKLAELERRIAQFLGFATVLTSVGQVYPRSLDHDVI  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAG SS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGASSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVI RE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIARE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMRE GAEPDLLDRL AD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMRERGAEPDLLDRLGADDR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADKKAF GAAGDQVD+V A+VDALVSRYPDAAKY PGAIL
Sbjct  421  LPLDRAALDAALADKKAFTGAAGDQVDEVAALVDALVSRYPDAAKYAPGAIL  472


>gi|41406709|ref|NP_959545.1| adenylosuccinate lyase [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395059|gb|AAS02928.1| PurB [Mycobacterium avium subsp. paratuberculosis K-10]
Length=472

 Score =  822 bits (2122),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/472 (89%), Positives = 443/472 (94%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLA RYASAEMVAIWSPEAKVV+ERRLWLAVLRAQ +LGVAV    +ADYERV++
Sbjct  1    MSIPNVLAARYASAEMVAIWSPEAKVVAERRLWLAVLRAQQQLGVAVPAEAIADYERVLE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASI+ RER+LRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  61   DVDLASIADRERLLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  121  AHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALARLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL+GGD A LA+LERRVA+FLGF+ V  SVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTSQDMLDLIGGDPAKLAELERRVAEFLGFSMVLTSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVIGRE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIGRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMREHGAEPDLL+RLAAD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMREHGAEPDLLERLAADER  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD++AF GAA DQVD+V A VDALVSRYPDAAKYTPGAIL
Sbjct  421  LPLDRAALDAALADRRAFTGAAADQVDEVAAQVDALVSRYPDAAKYTPGAIL  472


>gi|296166475|ref|ZP_06848907.1| adenylosuccinate lyase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295898236|gb|EFG77810.1| adenylosuccinate lyase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=483

 Score =  822 bits (2122),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/472 (89%), Positives = 438/472 (93%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            VSIPNVLA RYASA+MVAIWSPEAKVV+ERRLWLAVLRAQAELGV V    +ADYERVV+
Sbjct  12   VSIPNVLAARYASADMVAIWSPEAKVVAERRLWLAVLRAQAELGVDVPPDAIADYERVVE  71

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDLASI+ RER LRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  72   DVDLASIAERERALRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVF  131

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            +HG+A VARL ERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL R+RELIDR
Sbjct  132  SHGIAVVARLTERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALTRVRELIDR  191

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDLL GD + LADLERRVA FLGFATV  SVGQVYPRSLDHDV+
Sbjct  192  YPLRGIKGPMGTAQDMLDLLDGDASRLADLERRVAQFLGFATVLTSVGQVYPRSLDHDVL  251

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  252  SALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  311

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI RE
Sbjct  312  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIARE  371

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATT+VL+AAVRAGMGRE+AH +I EHAVATALAMRE G EPDLLDRLAAD R
Sbjct  372  LDRYLPFLATTRVLIAAVRAGMGREAAHHVIREHAVATALAMRERGTEPDLLDRLAADER  431

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADK AF GAAGDQVD+V AMVDALVSRYPDAAKY PGAIL
Sbjct  432  LPLDRAALDAALADKNAFTGAAGDQVDEVAAMVDALVSRYPDAAKYAPGAIL  483


>gi|118471019|ref|YP_890074.1| adenylosuccinate lyase [Mycobacterium smegmatis str. MC2 155]
 gi|118172306|gb|ABK73202.1| adenylosuccinate lyase [Mycobacterium smegmatis str. MC2 155]
Length=474

 Score =  820 bits (2117),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 400/472 (85%), Positives = 432/472 (92%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            V+IPNVLA RYAS EMVAIWSPEAK+++ERRLWLAVLRAQAELGVAV D V+ DYERV++
Sbjct  3    VTIPNVLANRYASDEMVAIWSPEAKIIAERRLWLAVLRAQAELGVAVPDGVVEDYERVLE  62

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDL SI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR+SLE++F
Sbjct  63   NVDLESIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRQSLELVF  122

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            +HGVA VARLAERAV YRDL+MAGRSHNVAAQATTLGKRFASAA+E ++AL RLRELIDR
Sbjct  123  SHGVAVVARLAERAVVYRDLVMAGRSHNVAAQATTLGKRFASAAEETLVALTRLRELIDR  182

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRG+KGPMGT QDMLDL GGD   LADLERRVA+FLGF  VF SVGQVYPRSLDHDV+
Sbjct  183  YPLRGVKGPMGTAQDMLDLFGGDVGKLADLERRVAEFLGFTEVFTSVGQVYPRSLDHDVL  242

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQ GAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  243  SALVQFGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  302

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI RE
Sbjct  303  GYASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQTETFLTVLDEFGAYPAVIQRE  362

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATT++LMAAVRAG+GRE+AH +I EHAVA ALAMRE G EPDL+DRLA DPR
Sbjct  363  LDRYLPFLATTRILMAAVRAGVGREAAHEVIKEHAVAVALAMREQGREPDLIDRLAGDPR  422

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L + ALEAAL DK+AF GAAGDQVD VVA V  LVSRYP+AAKYT GAIL
Sbjct  423  LPLDKVALEAALEDKQAFTGAAGDQVDGVVAAVGELVSRYPEAAKYTSGAIL  474


>gi|108801529|ref|YP_641726.1| adenylosuccinate lyase [Mycobacterium sp. MCS]
 gi|108771948|gb|ABG10670.1| adenylosuccinate lyase [Mycobacterium sp. MCS]
Length=477

 Score =  813 bits (2101),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 403/475 (85%), Positives = 432/475 (91%), Gaps = 3/475 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVA---VADSVLADYER  57
            V+IPNVLA RYAS +MVAIWSPEAK+V+ERRLWLAVLRAQ ELG+    V D V+ADYER
Sbjct  3    VTIPNVLANRYASEDMVAIWSPEAKIVAERRLWLAVLRAQIELGMGNTVVPDGVVADYER  62

Query  58   VVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  117
            V+D VDLASI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE
Sbjct  63   VLDQVDLASIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  122

Query  118  VIFAHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLREL  177
            ++ AHGVA VARLAE+AVSYRDL+MAGRSHNVAAQATTLGKRFASAA+E ++AL+R+ EL
Sbjct  123  LVHAHGVAVVARLAEKAVSYRDLVMAGRSHNVAAQATTLGKRFASAAEETLLALQRVEEL  182

Query  178  IDRYPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDH  237
            I RYPLRGIKGPMGT QDMLDL GGD A LADLERRVA+FLGF  VF SVGQVYPRSLDH
Sbjct  183  IARYPLRGIKGPMGTAQDMLDLFGGDTAKLADLERRVAEFLGFRDVFTSVGQVYPRSLDH  242

Query  238  DVVSALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  297
            DVVSALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQV
Sbjct  243  DVVSALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  302

Query  298  VLRGYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI  357
            VLRGY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI
Sbjct  303  VLRGYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQTETFLTVLDEFGAYPAVI  362

Query  358  GRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAA  417
             RELDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAA
Sbjct  363  QRELDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMREKGQEPDLLDRLAA  422

Query  418  DPRLTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            DPRL L R ALE ALADK+AF+GAAGDQVD V   VD LVSRYP+AAKYT GAIL
Sbjct  423  DPRLPLDRVALEDALADKQAFSGAAGDQVDRVAQAVDELVSRYPEAAKYTSGAIL  477


>gi|119870683|ref|YP_940635.1| adenylosuccinate lyase [Mycobacterium sp. KMS]
 gi|119696772|gb|ABL93845.1| adenylosuccinate lyase [Mycobacterium sp. KMS]
Length=475

 Score =  812 bits (2097),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 402/475 (85%), Positives = 432/475 (91%), Gaps = 3/475 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVA---VADSVLADYER  57
            ++IPNVLA RYAS +MVAIWSPEAK+V+ERRLWLAVLRAQ ELG+    V D V+ADYER
Sbjct  1    MTIPNVLANRYASEDMVAIWSPEAKIVAERRLWLAVLRAQIELGMGNTVVPDGVVADYER  60

Query  58   VVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  117
            V+D VDLASI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE
Sbjct  61   VLDQVDLASIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  120

Query  118  VIFAHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLREL  177
            ++ AHGVA VARLAE+AVSYRDL+MAGRSHNVAAQATTLGKRFASAA+E ++AL+R+ EL
Sbjct  121  LVHAHGVAVVARLAEKAVSYRDLVMAGRSHNVAAQATTLGKRFASAAEETLLALQRVEEL  180

Query  178  IDRYPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDH  237
            I RYPLRGIKGPMGT QDMLDL GGD A LADLERRVA+FLGF  VF SVGQVYPRSLDH
Sbjct  181  IARYPLRGIKGPMGTAQDMLDLFGGDTAKLADLERRVAEFLGFRDVFTSVGQVYPRSLDH  240

Query  238  DVVSALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  297
            DVVSALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQV
Sbjct  241  DVVSALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  300

Query  298  VLRGYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI  357
            VLRGY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI
Sbjct  301  VLRGYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQTETFLTVLDEFGAYPAVI  360

Query  358  GRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAA  417
             RELDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAA
Sbjct  361  QRELDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMREKGQEPDLLDRLAA  420

Query  418  DPRLTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            DPRL L R ALE ALADK+AF+GAAGDQVD V   VD LVSRYP+AAKYT GAIL
Sbjct  421  DPRLPLDRVALEDALADKQAFSGAAGDQVDRVAQAVDELVSRYPEAAKYTSGAIL  475


>gi|120406093|ref|YP_955922.1| adenylosuccinate lyase [Mycobacterium vanbaalenii PYR-1]
 gi|119958911|gb|ABM15916.1| adenylosuccinate lyase [Mycobacterium vanbaalenii PYR-1]
Length=491

 Score =  811 bits (2096),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 398/472 (85%), Positives = 434/472 (92%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            V +P+VLA RYAS EMVAIWSPEAK+V+ERRLWLAVL+AQAELGV V D V+ADYERV++
Sbjct  20   VPVPDVLAHRYASEEMVAIWSPEAKIVAERRLWLAVLKAQAELGVGVPDGVVADYERVLE  79

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDLASI+ARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++ 
Sbjct  80   EVDLASIAARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVH  139

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            A G+A VARLAERA  YRDL+MAGRSHNVAAQATTLGKRFASAA+E+++AL+R+RELIDR
Sbjct  140  ARGIAVVARLAERAALYRDLVMAGRSHNVAAQATTLGKRFASAAEELLVALQRVRELIDR  199

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL  GD   LADLERRVA FLGF  +F SVGQVYPRSLDHDVV
Sbjct  200  YPLRGIKGPMGTAQDMLDLFDGDTDRLADLERRVAGFLGFTDIFTSVGQVYPRSLDHDVV  259

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSS+AHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  260  SALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  319

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI RE
Sbjct  320  GYASMTAELAGAQWNEGDVFCSVVRRVALPDAFFALDGQTETFLTVLDEFGAYPAVIQRE  379

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE GAEPDLLDRLAADPR
Sbjct  380  LDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMREKGAEPDLLDRLAADPR  439

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADK+ F GAAGDQVD VVA VD L++RYP+AA+YT GAIL
Sbjct  440  LPLDRQALDAALADKQVFTGAAGDQVDRVVAAVDDLIARYPEAAEYTSGAIL  491


>gi|126437514|ref|YP_001073205.1| adenylosuccinate lyase [Mycobacterium sp. JLS]
 gi|126237314|gb|ABO00715.1| adenylosuccinate lyase [Mycobacterium sp. JLS]
Length=475

 Score =  810 bits (2093),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 401/475 (85%), Positives = 432/475 (91%), Gaps = 3/475 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVA---VADSVLADYER  57
            ++IPNVLA RYAS +MVAIWSPEAK+V+ERRLWLAVLRAQ ELG+    V D V+ADYER
Sbjct  1    MTIPNVLANRYASEDMVAIWSPEAKIVAERRLWLAVLRAQIELGMGNTVVPDGVVADYER  60

Query  58   VVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  117
            V+D VDLASI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE
Sbjct  61   VLDQVDLASIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  120

Query  118  VIFAHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLREL  177
            ++ AHGVA VARLAE+AVSYRDL+MAGRSHNVAAQATTLGKRFASAA+E ++AL+R+ EL
Sbjct  121  LVHAHGVAVVARLAEKAVSYRDLVMAGRSHNVAAQATTLGKRFASAAEETLLALQRVEEL  180

Query  178  IDRYPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDH  237
            I RYPLRGIKGPMGT QDMLDL GGD A LADLERRVA+FLGF  VF SVGQVYPRSLDH
Sbjct  181  IARYPLRGIKGPMGTAQDMLDLFGGDTAKLADLERRVAEFLGFRDVFTSVGQVYPRSLDH  240

Query  238  DVVSALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  297
            DVVSALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQV
Sbjct  241  DVVSALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  300

Query  298  VLRGYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI  357
            VLRGY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI
Sbjct  301  VLRGYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQTETFLTVLDEFGAYPAVI  360

Query  358  GRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAA  417
             RELDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAA
Sbjct  361  QRELDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMREKGQEPDLLDRLAA  420

Query  418  DPRLTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            DPRL L R ALE ALADK+AF+GAAGDQVD V   VD LVSRYP+AA+YT GAIL
Sbjct  421  DPRLPLDRVALEDALADKQAFSGAAGDQVDRVAEAVDELVSRYPEAAQYTSGAIL  475


>gi|240172324|ref|ZP_04750983.1| adenylosuccinate lyase [Mycobacterium kansasii ATCC 12478]
Length=471

 Score =  810 bits (2092),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/472 (88%), Positives = 439/472 (94%), Gaps = 1/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            + IPNVLA+RYASAEMVAIWSP+AKVV+ERRLWLAVLRAQAEL V V    +ADYERV+D
Sbjct  1    MGIPNVLASRYASAEMVAIWSPQAKVVAERRLWLAVLRAQAELEVEVPQEAIADYERVLD  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            DVDL SI+ARERVLRHDVKARIEEFN LAGH+HVHKGMTSRDLTENVEQLQIR+SLE++F
Sbjct  61   DVDLDSIAARERVLRHDVKARIEEFNDLAGHQHVHKGMTSRDLTENVEQLQIRQSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            +HGVA VARLAERAV+YRDL+M GRSHNVAAQATTLGKRFASAAQE +IAL RLRELIDR
Sbjct  121  SHGVAVVARLAERAVAYRDLVMTGRSHNVAAQATTLGKRFASAAQETLIALTRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDLLGG+ A LA LERR+ADFLGF+TV  SVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTAQDMLDLLGGEPARLARLERRIADFLGFSTVLTSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERV+GLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVDGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQ+ETFLTVLDEFGAYP VI RE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQLETFLTVLDEFGAYPRVIQRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRESAH +I EHA+ATALAMRE GAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGRESAHHVIREHAIATALAMRE-GAEPDLLDRLAADPR  419

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD+KAF GAA DQVD+VVAMVD LV RYP+AAKYTPGAIL
Sbjct  420  LPLDRAALDAALADRKAFTGAAADQVDEVVAMVDKLVGRYPEAAKYTPGAIL  471


>gi|315442644|ref|YP_004075523.1| adenylosuccinate lyase [Mycobacterium sp. Spyr1]
 gi|315260947|gb|ADT97688.1| adenylosuccinate lyase [Mycobacterium sp. Spyr1]
Length=472

 Score =  806 bits (2083),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 397/472 (85%), Positives = 434/472 (92%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLA RYAS EMVAIWSPEAK+V+ERRLW+AVL+AQAELGV V D V+ DYERV++
Sbjct  1    MSIPNVLANRYASEEMVAIWSPEAKIVAERRLWIAVLKAQAELGVPVPDGVVDDYERVLE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDLASI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++ 
Sbjct  61   NVDLASIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVH  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA VARLAERA  YRD++MAGRSHNVAAQATTLGKRFASAA+EM++AL+R+ ELIDR
Sbjct  121  AHGVAVVARLAERAALYRDVVMAGRSHNVAAQATTLGKRFASAAEEMLVALKRVGELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL  GD + LADLERRVA FLGF  +F SVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTAQDMLDLFDGDTSRLADLERRVAGFLGFTDMFTSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMN+RSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNSRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI RE
Sbjct  301  GYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFALDGQTETFLTVLDEFGAYPAVIQRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE GAEPDLLDRLAADPR
Sbjct  361  LDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMRERGAEPDLLDRLAADPR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD++AF+GAAGDQVD VVA V+ LV+RYP AA+YT GAIL
Sbjct  421  LPLDRPALDAALADRQAFSGAAGDQVDRVVAEVEDLVARYPGAAEYTSGAIL  472


>gi|145222205|ref|YP_001132883.1| adenylosuccinate lyase [Mycobacterium gilvum PYR-GCK]
 gi|145214691|gb|ABP44095.1| adenylosuccinate lyase [Mycobacterium gilvum PYR-GCK]
Length=481

 Score =  806 bits (2083),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 398/472 (85%), Positives = 433/472 (92%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            VSIPNVLA RYAS EMVAIWSPEAK+V+ERRLW+AVL+AQAELGV V D V+ DYERV++
Sbjct  10   VSIPNVLANRYASEEMVAIWSPEAKIVAERRLWIAVLKAQAELGVPVPDGVVDDYERVLE  69

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDLASI+ARERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE++ 
Sbjct  70   NVDLASIAARERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLELVH  129

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA VARLAERA  YRD++MAGRSHNVAAQATTLGKRFASAA+EM++AL+R+ ELIDR
Sbjct  130  AHGVAVVARLAERAALYRDVVMAGRSHNVAAQATTLGKRFASAAEEMLVALKRVGELIDR  189

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL  GD   LADLERRVA FLGF  +F SVGQVYPRSLDHDVV
Sbjct  190  YPLRGIKGPMGTAQDMLDLFDGDTERLADLERRVAGFLGFTDMFTSVGQVYPRSLDHDVV  249

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMN+RSCERVNGLQVVLR
Sbjct  250  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNSRSCERVNGLQVVLR  309

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI RE
Sbjct  310  GYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFALDGQTETFLTVLDEFGAYPAVIQRE  369

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATT++L+AAVRAG+GRE+AH +I EHAVA ALAMRE GAEPDLLDRLAADPR
Sbjct  370  LDRYLPFLATTRILIAAVRAGVGRETAHEVIKEHAVAVALAMRERGAEPDLLDRLAADPR  429

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALAD++AF+GAAGDQVD VVA V+ LV+RYP AA+YT GAIL
Sbjct  430  LPLDRPALDAALADRQAFSGAAGDQVDRVVAEVEDLVARYPGAAEYTSGAIL  481


>gi|183984884|ref|YP_001853175.1| adenylosuccinate lyase, PurB [Mycobacterium marinum M]
 gi|183178210|gb|ACC43320.1| adenylosuccinate lyase, PurB [Mycobacterium marinum M]
Length=475

 Score =  803 bits (2075),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/475 (87%), Positives = 432/475 (91%), Gaps = 3/475 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVAD---SVLADYER  57
            +S+PNVLA RYASAEMVAIWSP+AKVV+ERRLWLAVLRAQ ELG    D     +ADYER
Sbjct  1    MSVPNVLAARYASAEMVAIWSPQAKVVAERRLWLAVLRAQRELGAKGTDVPADAIADYER  60

Query  58   VVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  117
            V+DDVDL SI++RERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR+SL+
Sbjct  61   VIDDVDLDSIASRERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRQSLD  120

Query  118  VIFAHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLREL  177
            + FAHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLREL
Sbjct  121  LTFAHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALVRLREL  180

Query  178  IDRYPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDH  237
            IDRYPLRGIKGPMGT QDMLDLL GD A L DLE+RVADFLGF+TV  SVGQVYPRSLDH
Sbjct  181  IDRYPLRGIKGPMGTAQDMLDLLDGDSAKLTDLEQRVADFLGFSTVLTSVGQVYPRSLDH  240

Query  238  DVVSALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  297
            DVVSALVQLGAGPSSLAHTIRLMAGHEL TEGFA GQVGSSAMPHKMNTRSCERVNGLQV
Sbjct  241  DVVSALVQLGAGPSSLAHTIRLMAGHELVTEGFAAGQVGSSAMPHKMNTRSCERVNGLQV  300

Query  298  VLRGYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI  357
            VLRGYASM AELAGAQWNEGDVFCSVVRRV LPDSFFA+DGQ ETFLTVLDEFGAYPAVI
Sbjct  301  VLRGYASMAAELAGAQWNEGDVFCSVVRRVVLPDSFFAIDGQTETFLTVLDEFGAYPAVI  360

Query  358  GRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAA  417
             RELDRYLPFLATTKVLMAAVRAGMGRESAH +I EHAVATALAMREHG+EPDLLDRLAA
Sbjct  361  ARELDRYLPFLATTKVLMAAVRAGMGRESAHHVIREHAVATALAMREHGSEPDLLDRLAA  420

Query  418  DPRLTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            DPRL L R AL+AALADK AF GAA DQVD V A VDALV RYP+AAKY PGAIL
Sbjct  421  DPRLPLDRAALDAALADKAAFTGAAADQVDQVAAQVDALVGRYPEAAKYAPGAIL  475


>gi|118616331|ref|YP_904663.1| adenylosuccinate lyase [Mycobacterium ulcerans Agy99]
 gi|118568441|gb|ABL03192.1| adenylosuccinate lyase, PurB [Mycobacterium ulcerans Agy99]
Length=475

 Score =  802 bits (2072),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/475 (87%), Positives = 432/475 (91%), Gaps = 3/475 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVAD---SVLADYER  57
            +S+PNVLA RYASAEMVAIWSP+AKVV+ERRLWLAVLRAQ ELG    D     +ADYER
Sbjct  1    MSVPNVLAARYASAEMVAIWSPQAKVVAERRLWLAVLRAQRELGAKGTDVPADAIADYER  60

Query  58   VVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLE  117
            V+DDVDL SI++RERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR+SL+
Sbjct  61   VIDDVDLDSIASRERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRQSLD  120

Query  118  VIFAHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLREL  177
            + FAHGVA  ARLAERAV+YRDL+MAGRSHNVAAQATTLGKRFASAAQE +IAL RLREL
Sbjct  121  LTFAHGVAVAARLAERAVAYRDLVMAGRSHNVAAQATTLGKRFASAAQETLIALVRLREL  180

Query  178  IDRYPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDH  237
            IDRYPLRGIKGPMGT QDMLDLL GD A L DLE+RVADFLGF+TV  SVGQVYPRSLDH
Sbjct  181  IDRYPLRGIKGPMGTAQDMLDLLDGDSAKLTDLEQRVADFLGFSTVLTSVGQVYPRSLDH  240

Query  238  DVVSALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  297
            DVVSALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQV
Sbjct  241  DVVSALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQV  300

Query  298  VLRGYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVI  357
            VLRGYASM AELAGAQWNEGDVFCSVVRRV LPDSF A+DGQ ETFLTVLDEFGAYPAVI
Sbjct  301  VLRGYASMAAELAGAQWNEGDVFCSVVRRVVLPDSFIAIDGQTETFLTVLDEFGAYPAVI  360

Query  358  GRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAA  417
             RELDRYLPFLATTKVLMAAVRAGMGRESAH +I EHAVATALAMREHG+EPDLLDRLAA
Sbjct  361  ARELDRYLPFLATTKVLMAAVRAGMGRESAHHVIREHAVATALAMREHGSEPDLLDRLAA  420

Query  418  DPRLTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            DPRL L R AL+AALADK AF GAA DQV+ V A VDALV RYP+AAKY PGAIL
Sbjct  421  DPRLPLDRAALDAALADKAAFTGAAADQVEQVAAQVDALVGRYPEAAKYAPGAIL  475


>gi|333992227|ref|YP_004524841.1| adenylosuccinate lyase PurB [Mycobacterium sp. JDM601]
 gi|333488195|gb|AEF37587.1| adenylosuccinate lyase PurB [Mycobacterium sp. JDM601]
Length=472

 Score =  798 bits (2061),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 391/472 (83%), Positives = 425/472 (91%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLATRYASA M  IWSP AK+V+ERRLWLAVLRAQAELGV V +  +ADYE V++
Sbjct  1    MSIPNVLATRYASAAMTDIWSPRAKIVAERRLWLAVLRAQAELGVPVPEKAIADYEAVLE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDL SI+ARER+ RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR+SLE++F
Sbjct  61   NVDLESIAARERITRHDVKARIEEFNTLAGHEHVHKGMTSRDLTENVEQLQIRQSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            +HG+AAVARL   AV+YR+L+MAGRSHNVAAQATTLGKRFASAAQE +IAL+RL ELI R
Sbjct  121  SHGLAAVARLVSHAVAYRELVMAGRSHNVAAQATTLGKRFASAAQETLIALQRLEELIGR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGT QDMLDL  GD A LA+LERRVA+FLGF+TV  SVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTAQDMLDLFDGDTAKLAELERRVAEFLGFSTVLTSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ ETFLTVLDEFGAYPAVI RE
Sbjct  301  GYASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQTETFLTVLDEFGAYPAVITRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVA ALAMRE GAEPDLLDRLAAD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGREAAHEVIKEHAVAVALAMRERGAEPDLLDRLAADER  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+ A+AD++AF GAA DQVD ++A V ALV RYP AA Y PGAIL
Sbjct  421  LPLDRAALDVAIADRQAFTGAAADQVDQMMAEVTALVERYPSAAGYVPGAIL  472


>gi|2076619|emb|CAB08409.1| PurB [Mycobacterium leprae]
Length=487

 Score =  788 bits (2035),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/472 (87%), Positives = 437/472 (93%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            VSIPNVLA RYASAE+VAIWSPEA+V++ER+LWLAVLRAQAEL V +    +ADYERV+ 
Sbjct  16   VSIPNVLAARYASAELVAIWSPEARVIAERQLWLAVLRAQAELSVPMPVKAIADYERVLG  75

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDLASI+ARERVLRHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  76   EVDLASIAARERVLRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRRSLELVF  135

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
             HGVA VARLAE AVSYRDL+MAGRSHNVAAQATTLGKRFASA QE +IAL RLRELIDR
Sbjct  136  CHGVAVVARLAECAVSYRDLVMAGRSHNVAAQATTLGKRFASATQETLIALTRLRELIDR  195

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGD AALA+LE+R+A+FLGF  V  SVGQVYPRSLDHDV+
Sbjct  196  YPLRGIKGPMGTGQDMLDLLGGDAAALAELEQRIAEFLGFTKVLASVGQVYPRSLDHDVI  255

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAG SSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMN+RSCERVNGLQVVLR
Sbjct  256  SALVQLGAGSSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNSRSCERVNGLQVVLR  315

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYA+M AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVI RE
Sbjct  316  GYAAMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIRRE  375

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMRE GAEPDLLDRLAAD R
Sbjct  376  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMRECGAEPDLLDRLAADGR  435

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADKKAF GAA DQVD+VVAMVD LV RYP+AAKYTPGAIL
Sbjct  436  LPLDRAALDAALADKKAFTGAAADQVDEVVAMVDKLVGRYPEAAKYTPGAIL  487


>gi|15828195|ref|NP_302458.1| adenylosuccinate lyase [Mycobacterium leprae TN]
 gi|221230672|ref|YP_002504088.1| adenylosuccinate lyase [Mycobacterium leprae Br4923]
 gi|13093749|emb|CAC31186.1| adenylosuccinate lyase [Mycobacterium leprae]
 gi|219933779|emb|CAR72328.1| adenylosuccinate lyase [Mycobacterium leprae Br4923]
Length=472

 Score =  786 bits (2031),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 408/472 (87%), Positives = 437/472 (93%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            +SIPNVLA RYASAE+VAIWSPEA+V++ER+LWLAVLRAQAEL V +    +ADYERV+ 
Sbjct  1    MSIPNVLAARYASAELVAIWSPEARVIAERQLWLAVLRAQAELSVPMPVKAIADYERVLG  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDLASI+ARERVLRHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIRRSLE++F
Sbjct  61   EVDLASIAARERVLRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRRSLELVF  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
             HGVA VARLAE AVSYRDL+MAGRSHNVAAQATTLGKRFASA QE +IAL RLRELIDR
Sbjct  121  CHGVAVVARLAECAVSYRDLVMAGRSHNVAAQATTLGKRFASATQETLIALTRLRELIDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDLLGGD AALA+LE+R+A+FLGF  V  SVGQVYPRSLDHDV+
Sbjct  181  YPLRGIKGPMGTGQDMLDLLGGDAAALAELEQRIAEFLGFTKVLASVGQVYPRSLDHDVI  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAG SSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMN+RSCERVNGLQVVLR
Sbjct  241  SALVQLGAGSSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNSRSCERVNGLQVVLR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GYA+M AELAGAQWNEGDVFCSVVRRVALPDSFFA+DGQIETFLTVLDEFGAYPAVI RE
Sbjct  301  GYAAMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQIETFLTVLDEFGAYPAVIRRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            LDRYLPFLATTKVL+AAVRAGMGRE+AH +I EHAVATALAMRE GAEPDLLDRLAAD R
Sbjct  361  LDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATALAMRECGAEPDLLDRLAADGR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L R AL+AALADKKAF GAA DQVD+VVAMVD LV RYP+AAKYTPGAIL
Sbjct  421  LPLDRAALDAALADKKAFTGAAADQVDEVVAMVDKLVGRYPEAAKYTPGAIL  472


>gi|169627789|ref|YP_001701438.1| adenylosuccinate lyase [Mycobacterium abscessus ATCC 19977]
 gi|169239756|emb|CAM60784.1| Probable adenylosuccinate lyase (PurB) [Mycobacterium abscessus]
Length=472

 Score =  758 bits (1956),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 384/472 (82%), Positives = 416/472 (89%), Gaps = 0/472 (0%)

Query  1    VSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD  60
            + IPNVLA+RYAS  M A+WSP++KVV ER+LW+AVLRAQ +LG+ V D V+ DYERVV+
Sbjct  1    MQIPNVLASRYASDAMTALWSPQSKVVLERQLWIAVLRAQRDLGIEVPDGVIEDYERVVE  60

Query  61   DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF  120
            +VDL SISARERV RHDVKARIEEFNALAGHEH+HKGMTSRDLTENVEQLQIRRSLE + 
Sbjct  61   NVDLDSISARERVTRHDVKARIEEFNALAGHEHIHKGMTSRDLTENVEQLQIRRSLEYVH  120

Query  121  AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR  180
            AHGVA VARLA  AV YRD++MAGRSHNVAAQATTLGKRFASAA E ++AL RLREL+DR
Sbjct  121  AHGVAVVARLARHAVEYRDVVMAGRSHNVAAQATTLGKRFASAADETLLALTRLRELLDR  180

Query  181  YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV  240
            YPLRGIKGPMGTGQDMLDL  GD   LA+LE RVA FLGF+T   SVGQVYPRSLDHDVV
Sbjct  181  YPLRGIKGPMGTGQDMLDLFNGDVVKLAELEERVAGFLGFSTTLTSVGQVYPRSLDHDVV  240

Query  241  SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR  300
            SALVQLGAGPSSLAHTIRLMAGHEL TEGFAPGQVGSSAMPHKMNTRSCERVNGLQV+LR
Sbjct  241  SALVQLGAGPSSLAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVILR  300

Query  301  GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE  360
            GY SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG IETFLTVLDEFGAYPAVI RE
Sbjct  301  GYGSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGMIETFLTVLDEFGAYPAVIDRE  360

Query  361  LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR  420
            L RYLPFLATTKVLMAAVRAG+GRE AH +I EHAVATALAMRE GAEP+LL  LA D R
Sbjct  361  LRRYLPFLATTKVLMAAVRAGVGREEAHEVIKEHAVATALAMREKGAEPNLLGLLAEDAR  420

Query  421  LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L L  DALEAALAD+ +F GAA DQVD VVA V+AL + YPDAA Y+PGAIL
Sbjct  421  LPLDADALEAALADRASFTGAAADQVDRVVAEVEALAAEYPDAAVYSPGAIL  472


>gi|54022526|ref|YP_116768.1| adenylosuccinate lyase [Nocardia farcinica IFM 10152]
 gi|54014034|dbj|BAD55404.1| putative adenylosuccinate lyase [Nocardia farcinica IFM 10152]
Length=473

 Score =  738 bits (1904),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 385/470 (82%), Positives = 412/470 (88%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            +PNVLATRYAS E+V +WSPE K+V ERRLWL VLRAQ+ELG+ V D VLADYERVVD V
Sbjct  4    VPNVLATRYASPELVHLWSPEHKIVLERRLWLEVLRAQSELGIDVPDGVLADYERVVDRV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLA+I+ RERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR SLE + AH
Sbjct  64   DLAAIAERERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRLSLEHVHAH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA  ARLAERA  YR L+MAGRSHNVAAQATTLGKRFASAA E++IAL RLRELIDRYP
Sbjct  124  GVAIAARLAERAAEYRALVMAGRSHNVAAQATTLGKRFASAADELLIALTRLRELIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD A LA LE++VA  LGFATV  SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLGGDPAKLARLEQQVARHLGFATVLTSVGQVYPRSLDHDVLSA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+GAGPSSLAHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  244  LVQVGAGPSSLAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM AELAGAQWNEGDVFCSVVRRVALPD+FFAVDG +ETFLTVL EFGAYPAVI RELD
Sbjct  304  ASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAVDGMMETFLTVLAEFGAYPAVISRELD  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATT++LMAAVRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTRILMAAVRAGVGRETAHEVIKEHAVAVALAMREQGREPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+AALADK  F GAA DQ   V+A V  LV  YP+AA+YTP  IL
Sbjct  424  LDRAALDAALADKSVFVGAADDQTGAVIAQVQKLVEAYPEAARYTPSPIL  473


>gi|319951357|ref|ZP_08025182.1| adenylosuccinate lyase [Dietzia cinnamea P4]
 gi|319434954|gb|EFV90249.1| adenylosuccinate lyase [Dietzia cinnamea P4]
Length=485

 Score =  733 bits (1892),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 364/470 (78%), Positives = 406/470 (87%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            I NVLA+RYAS ++  +WS E K+V ER+LW+ VLRAQ +LG+ V D V+  YE V+D V
Sbjct  16   ISNVLASRYASVDLATLWSAEHKIVLERQLWIDVLRAQRDLGIDVPDGVIEAYEAVIDRV  75

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RERV RHDVKARIEEFN LAGHEH+HKGMTSRDLTENVEQLQ+ RSLE++   
Sbjct  76   DLASIAERERVTRHDVKARIEEFNDLAGHEHIHKGMTSRDLTENVEQLQVVRSLELVRDR  135

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVAA  RLAE AV++RD +MAGRSHNVAAQATTLGKRFASAA E+++AL R+  L++RYP
Sbjct  136  GVAAARRLAEHAVAHRDTVMAGRSHNVAAQATTLGKRFASAADELLVALERVESLLERYP  195

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD A +A+LE R+AD LGFA  F+SVGQVYPRSLDH+VVSA
Sbjct  196  LRGIKGPMGTAQDMLDLLGGDAAKMAELEGRIADHLGFARTFDSVGQVYPRSLDHEVVSA  255

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQLGAGPSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  256  LVQLGAGPSSLAQTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  315

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
             SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG  ETFLTVLDEFGAYPAVI +EL 
Sbjct  316  GSMAAELAGAQWNEGDVFCSVVRRVALPDAFFALDGMFETFLTVLDEFGAYPAVIDKELQ  375

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMAAVRAG+GRE AH  I E+AVA ALAMRE G EPDL+DRLAAD RL 
Sbjct  376  RYLPFLATTKVLMAAVRAGVGRELAHEAIKENAVAVALAMREEGREPDLIDRLAADERLP  435

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            LGR ALE ALAD+ AF GAAGDQVD VVA V+ALV+R+P+AA Y PG+IL
Sbjct  436  LGRPALEEALADRAAFIGAAGDQVDAVVARVEALVARHPEAAGYAPGSIL  485


>gi|262200836|ref|YP_003272044.1| adenylosuccinate lyase [Gordonia bronchialis DSM 43247]
 gi|262084183|gb|ACY20151.1| adenylosuccinate lyase [Gordonia bronchialis DSM 43247]
Length=479

 Score =  733 bits (1891),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/470 (78%), Positives = 396/470 (85%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            I NVLA RYASAE+ AIWS  AK+  ER+LW+AVL+AQ +LG+ V    +ADYERVV  +
Sbjct  10   ISNVLANRYASAELTAIWSASAKIELERQLWIAVLKAQRDLGIDVPADAIADYERVVGQI  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RERV RHDVKARIEEFNALAGHE +HKGMTSRDLTENVEQLQI RSLE + AH
Sbjct  70   DLASIAERERVTRHDVKARIEEFNALAGHEQIHKGMTSRDLTENVEQLQILRSLEHVHAH  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA +ARL ERA  Y  ++MAGRSHNVAAQATTLGKRFASAA E+MIAL RLRELIDRYP
Sbjct  130  GVAVLARLTERAAQYSSVVMAGRSHNVAAQATTLGKRFASAADELMIALTRLRELIDRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD   LADLE RVAD LGFA  F SVGQ+YPRSLDHDVVSA
Sbjct  190  LRGIKGPMGTSQDMLDLLGGDADKLADLENRVADHLGFARTFTSVGQIYPRSLDHDVVSA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+ A PSSLAHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL VVLRGY
Sbjct  250  LVQMAAAPSSLAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLAVVLRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
             SM AELAGAQWNEGDVFCSV+RRVALPD+FFA+DG +ETFLTVL EFGAYPAVI  ELD
Sbjct  310  GSMAAELAGAQWNEGDVFCSVIRRVALPDAFFAIDGLMETFLTVLAEFGAYPAVIANELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMA+VRAG+GRE+AH  I E+AVA ALAMRE G EPDLLDRLAAD R+ 
Sbjct  370  RYLPFLATTKVLMASVRAGVGRETAHEAIKENAVAVALAMREEGREPDLLDRLAADDRIP  429

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R  L+  LADK AF GAA  QV DV+A  + +++RYP+AA Y P  IL
Sbjct  430  LDRSQLDDLLADKAAFVGAAQAQVADVIAAAEKIIARYPEAAAYVPAPIL  479


>gi|226304514|ref|YP_002764472.1| adenylosuccinate lyase [Rhodococcus erythropolis PR4]
 gi|226183629|dbj|BAH31733.1| adenylosuccinate lyase [Rhodococcus erythropolis PR4]
Length=473

 Score =  733 bits (1891),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/470 (78%), Positives = 397/470 (85%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+VA+WSPE K+V ER+LW+AVLRAQAELG+ +    + DYERV+D+V
Sbjct  4    IPNVLANRYASPELVALWSPEYKIVLERQLWVAVLRAQAELGIDIPADAIDDYERVIDNV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RERV RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQI RSLE ++ H
Sbjct  64   DLASIADRERVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIVRSLEHVYNH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            G+A  ARL ERA  Y  ++MAGRSHNVAAQATTLGKRFASAA E+++AL RLR+LIDRYP
Sbjct  124  GIAVAARLGERAAEYSSIVMAGRSHNVAAQATTLGKRFASAADELLVALTRLRQLIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLL GD A L  LE +VA+ LGFA V  SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLDGDAAKLEQLEAKVAEHLGFAHVLTSVGQVYPRSLDHDVISA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+GAGPSS AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQV+LRGY
Sbjct  244  LVQVGAGPSSFAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVILRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
             SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG  ETFLTVL E GAYPAVI +EL 
Sbjct  304  GSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGMFETFLTVLIEMGAYPAVIEKELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATT+VLMAAVRAG+GRE+AH  I E+AVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTRVLMAAVRAGVGRETAHEAIKENAVAVALAMREEGKEPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALADK AF GAA  QVD VVA V  LV   P+AA Y P  IL
Sbjct  424  LDRAALDEALADKAAFVGAASAQVDAVVAEVQKLVDANPEAAAYAPSPIL  473


>gi|229494458|ref|ZP_04388221.1| adenylosuccinate lyase [Rhodococcus erythropolis SK121]
 gi|229318820|gb|EEN84678.1| adenylosuccinate lyase [Rhodococcus erythropolis SK121]
Length=473

 Score =  731 bits (1886),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/470 (78%), Positives = 396/470 (85%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+VA+WSPE K+V ER+LW+AVLRAQAELG+ +    + DYERV+D+V
Sbjct  4    IPNVLANRYASPELVALWSPEYKIVLERQLWVAVLRAQAELGIDIPADAIDDYERVIDNV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ RERV RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQI RSLE ++ H
Sbjct  64   DLESIADRERVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIVRSLEHVYNH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            G+A  ARL ERA  Y  ++MAGRSHNVAAQATTLGKRFASAA E+++AL RLR+LIDRYP
Sbjct  124  GIAVAARLGERAAEYSSIVMAGRSHNVAAQATTLGKRFASAADELLVALTRLRQLIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLL GD A L  LE +VA+ LGFA V  SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLDGDAAKLEQLEAKVAEHLGFAHVLTSVGQVYPRSLDHDVISA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+GAGPSS AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQV+LRGY
Sbjct  244  LVQVGAGPSSFAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVILRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
             SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG  ETFLTVL E GAYPAVI +EL 
Sbjct  304  GSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGMFETFLTVLIEMGAYPAVIEKELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATT+VLMAAVRAG+GRE+AH  I E+AVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTRVLMAAVRAGVGRETAHEAIKENAVAVALAMREEGKEPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALADK AF GAA  QVD VVA V  LV   P+AA Y P  IL
Sbjct  424  LDRVALDEALADKAAFVGAASAQVDAVVAEVQKLVDANPEAAAYAPSPIL  473


>gi|312138253|ref|YP_004005589.1| adenylosuccinate lyase purb [Rhodococcus equi 103S]
 gi|311887592|emb|CBH46904.1| adenylosuccinate lyase PurB [Rhodococcus equi 103S]
Length=473

 Score =  729 bits (1882),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 370/470 (79%), Positives = 402/470 (86%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS  +  +WSPE K+V ER+LWLAVL+AQAELG+ V    +ADYERV+  V
Sbjct  4    IPNVLANRYASPALKELWSPEHKIVLERQLWLAVLQAQAELGIDVPQEAVADYERVLHQV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ RERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQ+ RSLE ++ H
Sbjct  64   DLDSIAERERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQVLRSLEHVYDH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            G+A  ARLAERA  Y  ++MAGRSHNVAAQATTLGKRFASAA EM++ L R+RELIDRYP
Sbjct  124  GIAIAARLAERAAEYTGIVMAGRSHNVAAQATTLGKRFASAADEMLVGLTRVRELIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD A L  LE +VA+ LGFA VF SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLGGDAAKLEQLEAKVAEHLGFAHVFTSVGQVYPRSLDHDVLSA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQLGA  SS+AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  244  LVQLGAASSSMAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM +ELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ+ETFLTVL EFGAYPAVI  EL 
Sbjct  304  ASMASELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQMETFLTVLAEFGAYPAVIENELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMAAVRAG+GRE+AH  I EHAVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTKVLMAAVRAGVGRETAHEAIKEHAVAVALAMREEGKEPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALAD+ AF GAAG QVD VVA V  LV   PDAA+YTPG+IL
Sbjct  424  LDRAALDEALADRSAFVGAAGAQVDSVVAEVQKLVDANPDAARYTPGSIL  473


>gi|325674839|ref|ZP_08154526.1| adenylosuccinate lyase [Rhodococcus equi ATCC 33707]
 gi|325554425|gb|EGD24100.1| adenylosuccinate lyase [Rhodococcus equi ATCC 33707]
Length=473

 Score =  729 bits (1882),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 369/470 (79%), Positives = 403/470 (86%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS  +  +WSPE K+V ER+LWLAVL+AQAELG+ V    +ADYERV+  V
Sbjct  4    IPNVLANRYASPALKELWSPEHKIVLERQLWLAVLQAQAELGIDVPQEAVADYERVLHQV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ RERV RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQ+ RSLE ++ H
Sbjct  64   DLDSIAERERVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQVLRSLEHVYDH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            G+A  ARLAERA  Y  ++MAGRSHNVAAQATTLGKRFASAA EM++ L R+RELIDRYP
Sbjct  124  GIAIAARLAERAAEYTGIVMAGRSHNVAAQATTLGKRFASAADEMLVGLTRVRELIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD A L  LE +VA+ LGFA VF SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLGGDAAKLEQLEAKVAEHLGFAHVFTSVGQVYPRSLDHDVLSA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQLGA  SS+AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  244  LVQLGAASSSMAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM +ELAGAQWNEGDVFCSVVRRVALPD+FFA+DGQ+ETFLTVL EFGAYPAVI  EL 
Sbjct  304  ASMASELAGAQWNEGDVFCSVVRRVALPDAFFAIDGQMETFLTVLAEFGAYPAVIENELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMAAVRAG+GRE+AH  I EHAVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTKVLMAAVRAGVGRETAHEAIKEHAVAVALAMREEGKEPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALAD+ AF GAAG QVD VVA V  LV  +P+AA+YTPG+IL
Sbjct  424  LDRAALDEALADRSAFVGAAGAQVDSVVAEVQKLVDAHPEAARYTPGSIL  473


>gi|226364288|ref|YP_002782070.1| adenylosuccinate lyase [Rhodococcus opacus B4]
 gi|226242777|dbj|BAH53125.1| adenylosuccinate lyase [Rhodococcus opacus B4]
Length=473

 Score =  724 bits (1870),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 371/470 (79%), Positives = 400/470 (86%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+V +WSPE K+V ER+LWLAVLRAQAELG+ V    LADYERV++ V
Sbjct  4    IPNVLANRYASPELVELWSPEHKIVLERQLWLAVLRAQAELGIDVPAEALADYERVLEQV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ RERV RHDVKARIEEFNALAGHE VHKG+TSRDLTENVEQLQI RSLE + AH
Sbjct  64   DLDSIADRERVTRHDVKARIEEFNALAGHEQVHKGLTSRDLTENVEQLQILRSLEHVHAH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA  ARLAERA  Y  L+MAGRSHNVAAQATTLGKRFASAA E+++AL RLRELIDRYP
Sbjct  124  GVAVAARLAERAAEYSSLVMAGRSHNVAAQATTLGKRFASAADELLVALTRLRELIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLL GD + L  LE++VA+ LGF+ VF SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLDGDASKLEALEQKVAEHLGFSHVFTSVGQVYPRSLDHDVLSA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+ AGPSS AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  244  LVQVAAGPSSFAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG IETFLTVL EFGAYPAVI +EL 
Sbjct  304  ASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGLIETFLTVLAEFGAYPAVIEKELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMA VRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTKVLMALVRAGVGRETAHEVIKEHAVAVALAMREQGKEPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALADKKAF GAA  QV  VVA V  LV   P+AA Y P  IL
Sbjct  424  LDRAALDEALADKKAFIGAAEAQVATVVAQVQKLVDANPEAAAYQPSPIL  473


>gi|333918347|ref|YP_004491928.1| adenylosuccinate lyase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333480568|gb|AEF39128.1| Adenylosuccinate lyase [Amycolicicoccus subflavus DQS3-9A1]
Length=482

 Score =  723 bits (1866),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 357/458 (78%), Positives = 392/458 (86%), Gaps = 0/458 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            +PNVLATRY+S EM  +WSP+ K+V ER LWLAVLRAQ +LG+ V + V+ DYERV+  V
Sbjct  13   VPNVLATRYSSREMAHLWSPQNKIVLERELWLAVLRAQRDLGIEVPEGVIEDYERVISTV  72

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ARERV RHDVKARIEEF+ALAGHEH+HKGMTSRDLTENVEQLQIRR+LE++   
Sbjct  73   DLNSIAARERVTRHDVKARIEEFSALAGHEHIHKGMTSRDLTENVEQLQIRRALELVHER  132

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA   RL ERA  Y  L+MAGRSHNVAAQATTLGKRFASAA+E+++AL R+RELIDRYP
Sbjct  133  GVAVAVRLTERATQYSGLVMAGRSHNVAAQATTLGKRFASAAEEVLVALTRIRELIDRYP  192

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD   LA LE ++A  LGFA VF SVGQVYPRSLDHDVVSA
Sbjct  193  LRGIKGPMGTAQDMLDLLGGDEEKLAQLEVQIAGHLGFANVFTSVGQVYPRSLDHDVVSA  252

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL AGPSS AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  253  LVQLAAGPSSFAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  312

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG  ETFLTVL EFGAYPAVI REL+
Sbjct  313  ASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGLFETFLTVLGEFGAYPAVIERELE  372

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMAAVRAG+GRE+AH +I EHAVA ALAMRE GA  DLLDRLAAD RL 
Sbjct  373  RYLPFLATTKVLMAAVRAGVGRETAHEVIKEHAVAVALAMREQGAGQDLLDRLAADERLP  432

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRY  460
            L R AL+ ALADK AFAG+A  QV  VV  V+AL  ++
Sbjct  433  LDRGALDNALADKAAFAGSAQAQVARVVEAVEALAKQH  470


>gi|111021758|ref|YP_704730.1| adenylosuccinate lyase [Rhodococcus jostii RHA1]
 gi|110821288|gb|ABG96572.1| adenylosuccinate lyase [Rhodococcus jostii RHA1]
Length=473

 Score =  721 bits (1862),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 371/470 (79%), Positives = 400/470 (86%), Gaps = 0/470 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+V +WSPE K+V ER+LWLAVLRAQAELG+ V    LADYERV++ V
Sbjct  4    IPNVLANRYASPELVELWSPEHKIVLERQLWLAVLRAQAELGIDVPAEALADYERVLEQV  63

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DL SI+ RERV RHDVKARIEEFNALAGHE VHKG+TSRDLTENVEQLQI RSLE + AH
Sbjct  64   DLDSIADRERVTRHDVKARIEEFNALAGHEQVHKGLTSRDLTENVEQLQILRSLEHVHAH  123

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA  ARLAERA  Y  L+MAGRSHNVAAQATTLGKRFASAA E+++AL RLRELIDRYP
Sbjct  124  GVAVAARLAERAAEYGSLVMAGRSHNVAAQATTLGKRFASAADELLVALTRLRELIDRYP  183

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLL GD + L  LE++VA+ LGF+ VF SVGQVYPRSLDHDV+SA
Sbjct  184  LRGIKGPMGTAQDMLDLLDGDASKLEALEQKVAEHLGFSHVFTSVGQVYPRSLDHDVLSA  243

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+ AGPSS AHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGLQVVLRGY
Sbjct  244  LVQVAAGPSSFAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  303

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG IETFLTVL EFGAYPAVI +EL 
Sbjct  304  ASMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGLIETFLTVLAEFGAYPAVIEKELT  363

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMA VRAG+GRE+AH +I EHAVA ALAMRE G EPDLLDRLAAD RL 
Sbjct  364  RYLPFLATTKVLMALVRAGVGRETAHEVIKEHAVAVALAMREEGREPDLLDRLAADDRLP  423

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
            L R AL+ ALADKKAF GAA  QV  VVA V  LV   P+AA Y P  IL
Sbjct  424  LDRAALDEALADKKAFIGAAEAQVATVVAQVQKLVDADPEAAAYQPSPIL  473


>gi|343925803|ref|ZP_08765318.1| adenylosuccinate lyase [Gordonia alkanivorans NBRC 16433]
 gi|343764154|dbj|GAA12244.1| adenylosuccinate lyase [Gordonia alkanivorans NBRC 16433]
Length=475

 Score =  710 bits (1832),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 351/457 (77%), Positives = 385/457 (85%), Gaps = 0/457 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            I NVLA+RYAS ++  +WS   K+  ERRLW+AVL+AQA+LG+ V    +ADYERVVD V
Sbjct  6    IANVLASRYASTDLAELWSATTKIALERRLWIAVLKAQADLGIDVPADAIADYERVVDQV  65

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RERV RHDVKARIEEFNALAGHE +HKGMTSRDLTENVEQLQI RSLE + AH
Sbjct  66   DLASIADRERVTRHDVKARIEEFNALAGHEQIHKGMTSRDLTENVEQLQILRSLEHVHAH  125

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
            GVA +AR+ ERA  Y  ++MAGRSHNVAAQATTLGKRFASAA E+MIAL RLRELIDRYP
Sbjct  126  GVAVLARIVERAAQYSSVVMAGRSHNVAAQATTLGKRFASAADELMIALTRLRELIDRYP  185

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGPMGT QDMLDLLGGD   LADLE RVAD LGFA  F SVGQ+YPRSLDHDVVSA
Sbjct  186  LRGIKGPMGTSQDMLDLLGGDATKLADLEARVADHLGFARSFTSVGQIYPRSLDHDVVSA  245

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQ+ A PSSLAHTIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL VVLRGY
Sbjct  246  LVQVAAAPSSLAHTIRLMAGHELVTEGFQPGQVGSSAMPHKMNTRSCERVNGLAVVLRGY  305

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
             SM AELAGAQWNEGDVFCSVVRRVALPD+FFA+DG +ETFLTVL EFGAYPAVI  ELD
Sbjct  306  GSMAAELAGAQWNEGDVFCSVVRRVALPDAFFAIDGLMETFLTVLAEFGAYPAVIANELD  365

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPRLT  422
            RYLPFLATTKVLMA+VRAG+GRE+AH  I E+AVA ALAMRE G EPDLLDRLAAD R+ 
Sbjct  366  RYLPFLATTKVLMASVRAGVGRETAHEAIKENAVAVALAMREEGREPDLLDRLAADDRIP  425

Query  423  LGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSR  459
            L R  L+  LADK  F GAA  QV DV+A  + ++ +
Sbjct  426  LDRAQLDELLADKSVFVGAAEQQVADVIAAAEKIIGQ  462


>gi|302533146|ref|ZP_07285488.1| adenylosuccinate lyase [Streptomyces sp. C]
 gi|302442041|gb|EFL13857.1| adenylosuccinate lyase [Streptomyces sp. C]
Length=477

 Score =  707 bits (1825),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 350/471 (75%), Positives = 399/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ERRLWLAVLRAQ +LG+ V D+ LADYERV++ V
Sbjct  7    IPNVLAGRYASAELAVLWSPEYKVTLERRLWLAVLRAQKDLGIEVPDAALADYERVLETV  66

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  67   DLASIAEREKVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRLSLELVRDR  126

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  + +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  RL  L+ RYP
Sbjct  127  TVAVLARLGKLAGEHAELVMAGRSHNVAAQATTLGKRFATAADELLVAYDRLENLLQRYP  186

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD + LADLE+R+A  LGFA  F SVGQVYPRSLD+DVVSA
Sbjct  187  LRGIKGPVGTAQDMLDLLGGDASKLADLEQRIAAHLGFAQAFTSVGQVYPRSLDYDVVSA  246

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  247  LVQLAAAPSSIAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  306

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM AELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  307  ASMTAELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  366

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE+AH +I EHAVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  367  RYLPFLATTKVLMGAVRAGVGREAAHEVIKEHAVASALAMREQGAERNELLDKLAADERM  426

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+A +ADK +F GAAGDQV  VV+ ++A+   +P+AA Y PG+IL
Sbjct  427  PLDRAQLDALMADKLSFTGAAGDQVAAVVSRIEAIAKEHPEAAGYAPGSIL  477


>gi|182440065|ref|YP_001827784.1| adenylosuccinate lyase [Streptomyces griseus subsp. griseus NBRC 
13350]
 gi|178468581|dbj|BAG23101.1| putative adenylosuccinate lyase [Streptomyces griseus subsp. 
griseus NBRC 13350]
Length=480

 Score =  706 bits (1821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/471 (74%), Positives = 396/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAELAVLWSPEQKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRLSLELMRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  YR+L++AGRSHNVAAQATTLGKRFA+AA E+++A  RL +L+ RYP
Sbjct  130  TVAVLARLGKLAAEYRELVIAGRSHNVAAQATTLGKRFATAADELLVAHGRLEDLLSRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LADLE+R+A  LGFA  F SVGQVYPRSLD+DVV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGKLADLEQRIAGHLGFAEAFTSVGQVYPRSLDYDVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSVAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I EHAVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREEAHEAIKEHAVASALAMREQGAERNELLDKLAADDRI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+  +ADK +F GAAGDQV  +V  ++ +  +YP+AAKYTPG+IL
Sbjct  430  PLDRAQLDELMADKLSFTGAAGDQVTSLVDRIEKITEQYPEAAKYTPGSIL  480


>gi|329941565|ref|ZP_08290830.1| adenylosuccinate lyase [Streptomyces griseoaurantiacus M045]
 gi|329299282|gb|EGG43182.1| adenylosuccinate lyase [Streptomyces griseoaurantiacus M045]
Length=480

 Score =  705 bits (1820),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 351/471 (75%), Positives = 401/471 (86%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+  +WSPE KV  ERRLWLAVLRAQ +LG+ V ++ LADYERV+D+V
Sbjct  10   IPNVLAGRYASPELATLWSPEEKVRLERRLWLAVLRAQKDLGIEVPETALADYERVLDEV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ARE+V RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIRRSLE++   
Sbjct  70   DLASIAAREKVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRRSLELMRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + +  Y +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  R+ EL+ RYP
Sbjct  130  TVAVLARLGKLSGEYGELVMAGRSHNVAAQATTLGKRFATAADELLVAHGRVEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD + LA+LERR+A+ LGFA  F SVGQVYPRSLD++VV++
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDASRLAELERRIAEHLGFAHAFTSVGQVYPRSLDYEVVTS  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVATALAMRE GAE  +LLDRLAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVATALAMREQGAERNELLDRLAADERI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R+AL A +ADK +F GAA DQV  VVA +  +V ++P+AA YTPGAIL
Sbjct  430  PLDREALAALMADKLSFTGAAADQVTTVVARIGEIVKQHPEAAGYTPGAIL  480


>gi|326780734|ref|ZP_08239999.1| adenylosuccinate lyase [Streptomyces cf. griseus XylebKG-1]
 gi|326661067|gb|EGE45913.1| adenylosuccinate lyase [Streptomyces griseus XylebKG-1]
Length=480

 Score =  705 bits (1819),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/471 (74%), Positives = 396/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAELAVLWSPEHKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRLSLELMRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  YR+L++AGRSHNVAAQATTLGKRFA+AA E+++A  RL +L+ RYP
Sbjct  130  TVAVLARLGKLAAEYRELVIAGRSHNVAAQATTLGKRFATAADELLVAHGRLEDLLSRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LADLE+R+A  LGFA  F SVGQVYPRSLD+DVV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGKLADLEQRIAGHLGFAEAFTSVGQVYPRSLDYDVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSVAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I EHAVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREEAHEAIKEHAVASALAMREQGAERNELLDKLAADDRI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+  +ADK +F GAAGDQV  +V  ++ +  +YP+AAKYTPG+IL
Sbjct  430  PLDRAQLDELMADKLSFTGAAGDQVTSLVDRIEKITEQYPEAAKYTPGSIL  480


>gi|291440988|ref|ZP_06580378.1| adenylosuccinate lyase [Streptomyces ghanaensis ATCC 14672]
 gi|291343883|gb|EFE70839.1| adenylosuccinate lyase [Streptomyces ghanaensis ATCC 14672]
Length=480

 Score =  705 bits (1819),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 353/471 (75%), Positives = 395/471 (84%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ERRLWLAVLRAQ +LG+ V D+ +ADYERV+D V
Sbjct  10   IPNVLAGRYASAELATLWSPEQKVRLERRLWLAVLRAQKDLGIEVPDAAIADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQ+R SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQVRLSLELVRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL   A  Y +L++AGRSHNVAAQATTLGKRFA+AA E+++A  R+ EL+ RYP
Sbjct  130  AVAVLARLGRLAGEYGELVVAGRSHNVAAQATTLGKRFATAADELLVAYGRVEELLARYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LA+LERR+A  LGF   F SVGQVYPRSLD++VV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDADRLAELERRIAGHLGFTEAFTSVGQVYPRSLDYEVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVATALAMRE GAE  DLLD+LAAD RL
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVATALAMREQGAERNDLLDKLAADERL  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             LGRD LEA +ADK +F GAAGDQV  VV  VD +V + P+AA Y PGAIL
Sbjct  430  PLGRDELEALMADKLSFTGAAGDQVAAVVGRVDEIVKQRPEAAGYVPGAIL  480


>gi|254384272|ref|ZP_04999615.1| adenylosuccinate lyase [Streptomyces sp. Mg1]
 gi|194343160|gb|EDX24126.1| adenylosuccinate lyase [Streptomyces sp. Mg1]
Length=477

 Score =  703 bits (1815),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 349/471 (75%), Positives = 399/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ERRLWLAVLRAQ +LG+ V D+ LADYERV++ V
Sbjct  7    IPNVLAGRYASAELAVLWSPEYKVTLERRLWLAVLRAQKDLGIEVPDAALADYERVLETV  66

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIR SLE+    
Sbjct  67   DLASIAEREKVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRLSLELARDR  126

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  + +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  RL +L+ RYP
Sbjct  127  TVAVLARLGKLAGEHAELVMAGRSHNVAAQATTLGKRFATAADELLVAYARLEDLLGRYP  186

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD A LADLE+R+A  LGFA  F SVGQVYPRSLD+DVV+A
Sbjct  187  LRGIKGPVGTAQDMLDLLGGDAAKLADLEQRIAAHLGFAEAFTSVGQVYPRSLDYDVVTA  246

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  247  LVQLAAAPSSIAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  306

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  307  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  366

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE+AH +I EHAVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  367  RYLPFLATTKVLMGAVRAGVGREAAHEVIKEHAVASALAMREQGAERNELLDKLAADERM  426

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+A +ADK +F GAAGDQV  VV+ ++A+  ++P+AA Y PG+IL
Sbjct  427  PLDRAQLDALMADKLSFTGAAGDQVAAVVSRIEAIAKQHPEAAGYAPGSIL  477


>gi|302561897|ref|ZP_07314239.1| adenylosuccinate lyase [Streptomyces griseoflavus Tu4000]
 gi|302479515|gb|EFL42608.1| adenylosuccinate lyase [Streptomyces griseoflavus Tu4000]
Length=480

 Score =  702 bits (1813),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/471 (74%), Positives = 396/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ +ADYERV+D V
Sbjct  10   IPNVLAGRYASAELATLWSPEQKVRLERQLWLAVLRAQKDLGIEVPDAAIADYERVLDTV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQIRLSLELVRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL   A  Y +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  R+ EL+ RYP
Sbjct  130  TVAVLARLGRLAAEYGELVMAGRSHNVAAQATTLGKRFATAADELLVAYGRVEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD A LADLE+R+A  LGF+  F SVGQVYPRSLD++VV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAAKLADLEQRIARHLGFSQAFTSVGQVYPRSLDYEVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA T+RLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTVRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVATALAMRE GAE  DLL++LAAD RL
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVATALAMREQGAERNDLLNKLAADERL  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             LG+  LEA +ADK +F GAA DQV  V   ++ +V ++P+AA YTPGAIL
Sbjct  430  PLGKGELEALMADKLSFTGAASDQVGAVAGRIEEIVKQHPEAAGYTPGAIL  480


>gi|239986171|ref|ZP_04706835.1| adenylosuccinate lyase [Streptomyces roseosporus NRRL 11379]
 gi|291443113|ref|ZP_06582503.1| adenylosuccinate lyase [Streptomyces roseosporus NRRL 15998]
 gi|291346060|gb|EFE72964.1| adenylosuccinate lyase [Streptomyces roseosporus NRRL 15998]
Length=480

 Score =  700 bits (1807),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 345/471 (74%), Positives = 396/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAELAVLWSPEQKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRLSLELMRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  YR+L++AGRSHNVAAQATTLGKRFA+AA E+++A  RL +L+ RYP
Sbjct  130  TVAVLARLGKLAAEYRELVIAGRSHNVAAQATTLGKRFATAADELLVAYGRLEDLLSRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LA+LE+R+A  LGFA  F SVGQVYPRSLD+DVV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGKLAELEQRIAGHLGFAEAFTSVGQVYPRSLDYDVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSVAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGRELAHEAIKENAVASALAMREQGAERNELLDKLAADERI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+  +ADK +F GAAGDQV  +VA ++ +  ++P+AA YTPG+IL
Sbjct  430  PLDRAQLDELMADKLSFTGAAGDQVTSLVARIEEITKQHPEAAGYTPGSIL  480


>gi|344998290|ref|YP_004801144.1| adenylosuccinate lyase [Streptomyces sp. SirexAA-E]
 gi|344313916|gb|AEN08604.1| adenylosuccinate lyase [Streptomyces sp. SirexAA-E]
Length=477

 Score =  700 bits (1807),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 345/471 (74%), Positives = 393/471 (84%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYAS E+  +WSPE KV  ERRLWLAVLRAQ +LG+ V D+ LADYERVVD V
Sbjct  7    IPNVLAGRYASTELAVLWSPEQKVKLERRLWLAVLRAQKDLGIEVPDAALADYERVVDQV  66

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE++ RHDVKARIEEFNALAGHE VHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  67   DLASIAEREKITRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQIRLSLELMRDR  126

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  YR+L++AGRSHNVAAQATTLGKRFA+AA E+++   RL +L+DRYP
Sbjct  127  TVAVLARLGKLAAEYRELVLAGRSHNVAAQATTLGKRFATAADELLVGYGRLEDLLDRYP  186

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LADLE+R+A  LGF   F SVGQVYPRSLD+DVV+A
Sbjct  187  LRGIKGPVGTAQDMLDLLGGDADKLADLEQRIAGHLGFTQSFTSVGQVYPRSLDYDVVTA  246

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  247  LVQLAAAPSSVAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  306

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  307  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFAFDGLLETFLTVLDEFGAFPAVVARELD  366

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  367  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVASALAMREQGAERNELLDKLAADARI  426

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+A + DK +F GAAGDQV  +VA ++ +  +YP+AA Y PG+IL
Sbjct  427  PLDRAQLDALMEDKLSFTGAAGDQVTALVARIEKIAEQYPEAAGYIPGSIL  477


>gi|302549913|ref|ZP_07302255.1| adenylosuccinate lyase [Streptomyces viridochromogenes DSM 40736]
 gi|302467531|gb|EFL30624.1| adenylosuccinate lyase [Streptomyces viridochromogenes DSM 40736]
Length=480

 Score =  699 bits (1805),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/471 (74%), Positives = 396/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAELATLWSPEQKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDTV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQIRLSLELVRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  Y +L+MAGRSHNVAAQATTLGKRFA+ A E+++A  R+ EL+ RYP
Sbjct  130  TVAVLARLGKLAGEYGELVMAGRSHNVAAQATTLGKRFATGADELLVAYGRIEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD A LA+LE+R+A  LGF+  F SVGQVYPRSLD++VV+ 
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAAKLAELEQRIAGHLGFSQAFTSVGQVYPRSLDYEVVTT  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGRELAHEAIKENAVASALAMREQGAERNELLDKLAADARI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+A +ADK +F GAAGDQV  VVA V+ +V ++P AA YTPGAIL
Sbjct  430  PLDRAGLDALMADKLSFTGAAGDQVATVVARVEEIVKQHPRAAGYTPGAIL  480


>gi|289773043|ref|ZP_06532421.1| adenylosuccinate lyase [Streptomyces lividans TK24]
 gi|289703242|gb|EFD70671.1| adenylosuccinate lyase [Streptomyces lividans TK24]
Length=480

 Score =  697 bits (1800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/471 (74%), Positives = 395/471 (84%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ +ADYERV+D V
Sbjct  10   IPNVLAGRYASAELATLWSPEHKVKLERQLWLAVLRAQKDLGIEVPDAAIADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQIRLSLELVRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  Y +L+MAGRSHNVAAQATTLGKRFASAA E+++A  R+ EL+ RYP
Sbjct  130  SVAVLARLGKLAGEYGELVMAGRSHNVAAQATTLGKRFASAADELLVAYGRVEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LADLE+R+A  LGF+  F SVGQVYPRSLD++VV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGKLADLEQRIAGHLGFSQAFTSVGQVYPRSLDYEVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLTVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVR G+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRGGVGREVAHEAIKENAVASALAMREQGAERNELLDKLAADDRI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R AL+A +ADK +F GAA DQV  VV  ++ +V R+P AA YTPGAIL
Sbjct  430  PLDRAALDALMADKLSFTGAAADQVGVVVGRIEDIVKRHPQAAGYTPGAIL  480


>gi|297195725|ref|ZP_06913123.1| adenylosuccinate lyase [Streptomyces pristinaespiralis ATCC 25486]
 gi|197718932|gb|EDY62840.1| adenylosuccinate lyase [Streptomyces pristinaespiralis ATCC 25486]
Length=480

 Score =  697 bits (1798),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 345/471 (74%), Positives = 397/471 (85%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASA++  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAQLAVLWSPEQKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQ+R SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQVRLSLELMRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + +  Y +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  RL +L+ RYP
Sbjct  130  TVAVLARLGKLSGEYAELVMAGRSHNVAAQATTLGKRFATAADELLVAHGRLEDLLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD A LA+LE+R+A  LGF   F SVGQVYPRSLD+DVVSA
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAAKLAELEQRIAAHLGFGHAFTSVGQVYPRSLDYDVVSA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSS+A TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSVAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVASALAMREQGAERNELLDKLAADERI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+  +ADK +F GAAGDQV  VV+ ++ +  ++P+AA YTPGAIL
Sbjct  430  PLDRAQLDELMADKLSFTGAAGDQVTAVVSRIEEIAKQHPEAAAYTPGAIL  480


>gi|32141137|ref|NP_733528.1| adenylosuccinate lyase [Streptomyces coelicolor A3(2)]
 gi|24413746|emb|CAD55168.1| putative adenylosuccino lyase [Streptomyces coelicolor A3(2)]
Length=480

 Score =  696 bits (1797),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 347/471 (74%), Positives = 395/471 (84%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ +ADYERV++ V
Sbjct  10   IPNVLAGRYASAELATLWSPEHKVKLERQLWLAVLRAQKDLGIEVPDAAIADYERVLNQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR SLE++   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQIRLSLELVRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  Y +L+MAGRSHNVAAQATTLGKRFASAA E+++A  R+ EL+ RYP
Sbjct  130  SVAVLARLGKLAGEYGELVMAGRSHNVAAQATTLGKRFASAADELLVAYGRVEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LADLE+R+A  LGF+  F SVGQVYPRSLD++VV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGKLADLEQRIAGHLGFSQAFTSVGQVYPRSLDYEVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLTVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVR G+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRGGVGREVAHEAIKENAVASALAMREQGAERNELLDKLAADDRI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R AL+A +ADK +F GAA DQV  VV  ++ +V R+P AA YTPGAIL
Sbjct  430  PLDRAALDALMADKLSFTGAAADQVGVVVGRIEDIVKRHPQAAGYTPGAIL  480


>gi|126348508|emb|CAJ90231.1| putative adenylosuccino lyase [Streptomyces ambofaciens ATCC 
23877]
Length=480

 Score =  695 bits (1794),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 347/471 (74%), Positives = 394/471 (84%), Gaps = 1/471 (0%)

Query  3    IPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVDDV  62
            IPNVLA RYASAE+  +WSPE KV  ER+LWLAVLRAQ +LG+ V D+ LADYERV+D V
Sbjct  10   IPNVLAGRYASAELATLWSPEQKVKLERQLWLAVLRAQKDLGIEVPDAALADYERVLDQV  69

Query  63   DLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIFAH  122
            DLASI+ RE+V RHDVKARIEEFN LAGHEHVHKGMTSRDLTENVEQLQIR SLE+I   
Sbjct  70   DLASIAEREKVTRHDVKARIEEFNDLAGHEHVHKGMTSRDLTENVEQLQIRLSLELIRDR  129

Query  123  GVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDRYP  182
             VA +ARL + A  Y +L+MAGRSHNVAAQATTLGKRFA+AA E+++A  RL EL+ RYP
Sbjct  130  SVAVLARLGKLAGEYAELVMAGRSHNVAAQATTLGKRFATAADELLVAYGRLEELLGRYP  189

Query  183  LRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSA  242
            LRGIKGP+GT QDMLDLLGGD   LA+LE+R+A  LGF+  F SVGQVYPRSLD++VV+A
Sbjct  190  LRGIKGPVGTAQDMLDLLGGDAGRLAELEQRIAGHLGFSQAFTSVGQVYPRSLDYEVVTA  249

Query  243  LVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGY  302
            LVQL A PSSLA TIRLMAGHEL TEGF PGQVGSSAMPHKMNTRSCERVNGL V+LRGY
Sbjct  250  LVQLAAAPSSLAKTIRLMAGHELVTEGFKPGQVGSSAMPHKMNTRSCERVNGLMVILRGY  309

Query  303  ASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELD  362
            ASM  ELAG QWNEGDV CSVVRRVALPD+FFA+DG +ETFLTVLDEFGA+PAV+ RELD
Sbjct  310  ASMTGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLLETFLTVLDEFGAFPAVVARELD  369

Query  363  RYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAE-PDLLDRLAADPRL  421
            RYLPFLATTKVLM AVRAG+GRE AH  I E+AVA+ALAMRE GAE  +LLD+LAAD R+
Sbjct  370  RYLPFLATTKVLMGAVRAGVGREVAHEAIKENAVASALAMREQGAERNELLDKLAADERI  429

Query  422  TLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL  472
             L R  L+A +ADK +F GAA  QV  VV  ++ +V ++P AA YTPGAIL
Sbjct  430  PLDRAGLDALMADKLSFTGAAAGQVGVVVGRIEEIVKQHPAAAGYTPGAIL  480



Lambda     K      H
   0.321    0.134    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1000830144706




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40