BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0783c
Length=540
Score E
Sequences producing significant alignments: (Bits) Value
gi|253797730|ref|YP_003030731.1| multidrug resistance membrane e... 1066 0.0
gi|15607923|ref|NP_215297.1| multidrug resistance integral membr... 1066 0.0
gi|339297443|gb|AEJ49553.1| drug transporter [Mycobacterium tube... 1064 0.0
gi|15840198|ref|NP_335235.1| drug transporter [Mycobacterium tub... 1063 0.0
gi|339630852|ref|YP_004722494.1| multidrug resistance integral m... 1063 0.0
gi|340625801|ref|YP_004744253.1| putative multidrug resistance i... 944 0.0
gi|336458306|gb|EGO37285.1| drug resistance transporter, EmrB/Qa... 711 0.0
gi|118463591|ref|YP_880005.1| EmrB efflux protein [Mycobacterium... 709 0.0
gi|41406717|ref|NP_959553.1| hypothetical protein MAP0619c [Myco... 708 0.0
gi|254818437|ref|ZP_05223438.1| hypothetical protein MintA_00852... 696 0.0
gi|296166469|ref|ZP_06848901.1| drug transporter [Mycobacterium ... 695 0.0
gi|254773668|ref|ZP_05215184.1| EmrB efflux protein [Mycobacteri... 693 0.0
gi|289756871|ref|ZP_06516249.1| LOW QUALITY PROTEIN: multidrug r... 693 0.0
gi|16226140|gb|AAL16083.1|AF421382_1 EmrB efflux protein [Mycoba... 688 0.0
gi|240173126|ref|ZP_04751784.1| integral membrane drug efflux pr... 683 0.0
gi|342862172|ref|ZP_08718814.1| EmrB efflux protein [Mycobacteri... 682 0.0
gi|240172330|ref|ZP_04750989.1| integral membrane drug efflux pr... 668 0.0
gi|183984873|ref|YP_001853164.1| integral membrane drug efflux p... 666 0.0
gi|296166470|ref|ZP_06848902.1| drug transporter [Mycobacterium ... 651 0.0
gi|118616342|ref|YP_904674.1| integral membrane drug efflux prot... 648 0.0
gi|289568735|ref|ZP_06448962.1| multidrug resistance membrane ef... 637 1e-180
gi|183982530|ref|YP_001850821.1| integral membrane drug efflux p... 613 3e-173
gi|342862173|ref|ZP_08718815.1| EmrB efflux protein [Mycobacteri... 606 3e-171
gi|183980128|ref|YP_001848419.1| integral membrane efflux protei... 587 2e-165
gi|118465955|ref|YP_880004.1| EmrB efflux protein [Mycobacterium... 586 4e-165
gi|41406716|ref|NP_959552.1| hypothetical protein MAP0618c [Myco... 585 9e-165
gi|254773667|ref|ZP_05215183.1| EmrB efflux protein [Mycobacteri... 580 1e-163
gi|254818438|ref|ZP_05223439.1| EmrB efflux protein [Mycobacteri... 578 8e-163
gi|183983099|ref|YP_001851390.1| integral membrane drug efflux p... 573 3e-161
gi|183982968|ref|YP_001851259.1| integral membrane drug efflux p... 559 5e-157
gi|240168038|ref|ZP_04746697.1| integral membrane drug efflux pr... 480 3e-133
gi|312140993|ref|YP_004008329.1| mfs transporter [Rhodococcus eq... 470 2e-130
gi|183984924|ref|YP_001853215.1| multidrug resistance integral m... 467 2e-129
gi|54024315|ref|YP_118557.1| putative transporter [Nocardia farc... 462 7e-128
gi|326329297|ref|ZP_08195622.1| drug transporter [Nocardioidacea... 459 6e-127
gi|240170021|ref|ZP_04748680.1| multidrug resistance integral me... 458 9e-127
gi|258650304|ref|YP_003199460.1| EmrB/QacA subfamily drug resist... 452 5e-125
gi|226305233|ref|YP_002765191.1| drug resistance efflux protein ... 434 1e-119
gi|302867480|ref|YP_003836117.1| EmrB/QacA subfamily drug resist... 427 2e-117
gi|302530134|ref|ZP_07282476.1| elloramycin permease [Streptomyc... 422 7e-116
gi|119714403|ref|YP_921368.1| EmrB/QacA family drug resistance t... 420 3e-115
gi|330467678|ref|YP_004405421.1| EmrB/QacA subfamily drug resist... 416 6e-114
gi|326383993|ref|ZP_08205676.1| EmrB/QacA subfamily drug resista... 415 9e-114
gi|317124447|ref|YP_004098559.1| drug resistance transporter Emr... 414 2e-113
gi|226361044|ref|YP_002778822.1| drug resistance efflux protein ... 413 4e-113
gi|111018946|ref|YP_701918.1| major facilitator superfamily mult... 412 6e-113
gi|145593638|ref|YP_001157935.1| EmrB/QacA family drug resistanc... 407 2e-111
gi|159036624|ref|YP_001535877.1| EmrB/QacA family drug resistanc... 407 3e-111
gi|84497916|ref|ZP_00996713.1| putative transporter [Janibacter ... 404 2e-110
gi|118616372|ref|YP_904704.1| multidrug resistance integral memb... 397 3e-108
>gi|253797730|ref|YP_003030731.1| multidrug resistance membrane efflux protein emrB [Mycobacterium
tuberculosis KZN 1435]
gi|298524272|ref|ZP_07011681.1| drug transporter [Mycobacterium tuberculosis 94_M4241A]
gi|308231634|ref|ZP_07663900.1| multidrug resistance membrane efflux protein emrB [Mycobacterium
tuberculosis SUMu001]
12 more sequence titles
Length=545
Score = 1066 bits (2758), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 540/540 (100%), Positives = 540/540 (100%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 6 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 65
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 66 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 125
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 126 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 185
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 186 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 245
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 246 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 305
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR
Sbjct 306 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 365
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL
Sbjct 366 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 425
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA
Sbjct 426 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 485
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 486 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 545
>gi|15607923|ref|NP_215297.1| multidrug resistance integral membrane efflux protein EmrB [Mycobacterium
tuberculosis H37Rv]
gi|31791970|ref|NP_854463.1| multidrug resistance integral membrane efflux protein EmrB [Mycobacterium
bovis AF2122/97]
gi|121636706|ref|YP_976929.1| putative multidrug resistance integral membrane efflux protein
emrB [Mycobacterium bovis BCG str. Pasteur 1173P2]
44 more sequence titles
Length=540
Score = 1066 bits (2756), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 540/540 (100%), Positives = 540/540 (100%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR
Sbjct 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL
Sbjct 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA
Sbjct 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
>gi|339297443|gb|AEJ49553.1| drug transporter [Mycobacterium tuberculosis CCDC5180]
Length=545
Score = 1064 bits (2752), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 539/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 6 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 65
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 66 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 125
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 126 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 185
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 186 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 245
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 246 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 305
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR
Sbjct 306 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 365
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL
Sbjct 366 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 425
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQF HSEIIATAKKVALTPESGAGRGAA
Sbjct 426 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFKHSEIIATAKKVALTPESGAGRGAA 485
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 486 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 545
>gi|15840198|ref|NP_335235.1| drug transporter [Mycobacterium tuberculosis CDC1551]
gi|254231098|ref|ZP_04924425.1| multidrug resistance integral membrane efflux protein emrB [Mycobacterium
tuberculosis C]
gi|13880353|gb|AAK45049.1| drug transporter [Mycobacterium tuberculosis CDC1551]
gi|124600157|gb|EAY59167.1| multidrug resistance integral membrane efflux protein emrB [Mycobacterium
tuberculosis C]
gi|323720814|gb|EGB29884.1| multidrug resistance membrane efflux protein emrB [Mycobacterium
tuberculosis CDC1551A]
Length=545
Score = 1063 bits (2749), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 539/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 6 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 65
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 66 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 125
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 126 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 185
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 186 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 245
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 246 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 305
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR
Sbjct 306 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 365
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGM CSMMPLSGAAVQTL
Sbjct 366 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMVCSMMPLSGAAVQTL 425
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA
Sbjct 426 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 485
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 486 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 545
>gi|339630852|ref|YP_004722494.1| multidrug resistance integral membrane efflux protein EMRB [Mycobacterium
africanum GM041182]
gi|339330208|emb|CCC25866.1| putative multidrug resistance integral membrane efflux protein
EMRB [Mycobacterium africanum GM041182]
Length=540
Score = 1063 bits (2748), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 539/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR
Sbjct 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL
Sbjct 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA
Sbjct 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHR APLLSA
Sbjct 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRTAPLLSA 540
>gi|340625801|ref|YP_004744253.1| putative multidrug resistance integral membrane efflux protein
EMRB [Mycobacterium canettii CIPT 140010059]
gi|340003991|emb|CCC43126.1| putative multidrug resistance integral membrane efflux protein
EMRB [Mycobacterium canettii CIPT 140010059]
Length=540
Score = 944 bits (2441), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 528/540 (98%), Positives = 533/540 (99%), Gaps = 0/540 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A NILLLIIFRV+QGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 121 GSLLCALALNILLLIIFRVLQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDY+GLLLLSPG
Sbjct 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYLGLLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIP ITGLALIAAFVAHSWYR EHPLIDMRLFQNRAVA
Sbjct 241 LATFLFGVSSSPARGTMADRHVLIPVITGLALIAAFVAHSWYRAEHPLIDMRLFQNRAVA 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGA+MDRR
Sbjct 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAVMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL
Sbjct 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
AP QIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSE IATAKKVALTPES AGRG A
Sbjct 421 APRQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSETIATAKKVALTPESAAGRGVA 480
Query 481 VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
VDPSSLPRQT+FAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 481 VDPSSLPRQTSFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
>gi|336458306|gb|EGO37285.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium
avium subsp. paratuberculosis S397]
Length=560
Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 356/535 (67%), Positives = 423/535 (80%), Gaps = 4/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A P P P G+P + +R YPD+LD LLR +GVC+LA+VMA +DVT
Sbjct 23 MLSNAMDEAPYAAAKTP-PHAPTGQPGATEREYPDKLDAALLRISGVCILATVMAILDVT 81
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSVLAF L
Sbjct 82 VVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVLAFML 141
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A N+L LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 142 GSLLCALAANVLQLIVFRVVQGIGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 201
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI WRWIFL+N+P+GL + LAA+VFPRD PA SE FD +G+LLLSPG
Sbjct 202 IGGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPARSETFDAVGVLLLSPG 261
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VSS P RGT+ADRHVLIPA GL LIA FV H+W+R +HPLID+RLF+N +
Sbjct 262 LATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRADHPLIDLRLFRNPVLT 321
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+
Sbjct 322 HANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQ 381
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVGI LI AGLG FAFGVARQA YLP L GLAI G+GMGC+MMPLS A+VQ L
Sbjct 382 GPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGLGMGCTMMPLSVASVQAL 441
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G
Sbjct 442 APHQIARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAGGTP 501
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+D S++PRQ+ F +LHDLSHAY VFVIA ALVV T+IPA+FLPK+ A+
Sbjct 502 IDQSAIPRQSLAPGFWGNVLHDLSHAYTAVFVIAVALVVCTIIPASFLPKKPATE 556
>gi|118463591|ref|YP_880005.1| EmrB efflux protein [Mycobacterium avium 104]
gi|118164878|gb|ABK65775.1| EmrB efflux protein [Mycobacterium avium 104]
Length=560
Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 355/535 (67%), Positives = 422/535 (79%), Gaps = 4/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A P P P G+P + +R YPD+LD LLR +GVC+LA+VMA +DVT
Sbjct 23 MLSNAMDEAPYAAAKTP-PHAPTGQPGATEREYPDKLDAALLRISGVCILATVMAILDVT 81
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSV+AF L
Sbjct 82 VVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVVAFML 141
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A NIL LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 142 GSLLCALAANILQLIVFRVVQGIGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 201
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+ GPILGGWLI WRWIFL+N+P+GL + LAA+VFPRD PA SE FD +G+LLLSPG
Sbjct 202 IAGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPARSETFDAVGVLLLSPG 261
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VSS P RGT+ADRHVLIPA GL LIA FV H+W+R +HPLID+RLF+N +
Sbjct 262 LATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRADHPLIDLRLFRNPVLT 321
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+
Sbjct 322 HANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQ 381
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVGI LI AGLG FAFGVARQA YLP L GLAI G+GMGC+MMPLS A+VQ L
Sbjct 382 GPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGLGMGCTMMPLSVASVQAL 441
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G
Sbjct 442 APHQIARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAGGTP 501
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+D S++PRQ+ F +LHDLSHAY VFVIA ALVV T+IPA+FLPK+ A+
Sbjct 502 IDQSAIPRQSLAPGFGGNVLHDLSHAYTAVFVIAVALVVCTIIPASFLPKKPAAE 556
>gi|41406717|ref|NP_959553.1| hypothetical protein MAP0619c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41395067|gb|AAS02936.1| hypothetical protein MAP_0619c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=538
Score = 708 bits (1827), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 355/535 (67%), Positives = 423/535 (80%), Gaps = 4/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A P P P G+P + +R YPD+LD LLR +GVC+LA+VMA +DVT
Sbjct 1 MLSNAMDEAPYAAAKTP-PHAPTGQPGATEREYPDKLDAALLRISGVCILATVMAILDVT 59
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSVLAF L
Sbjct 60 VVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVLAFML 119
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A N+L LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 120 GSLLCALAANVLQLIVFRVVQGIGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 179
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI WRWIFL+N+P+GL + LAA+VFPRD PA SE FD +G+LLLSPG
Sbjct 180 IGGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPARSETFDAVGVLLLSPG 239
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VSS P RGT+ADRHVLIPA GL LIA FV H+W+R +HPLID+RLF+N +
Sbjct 240 LATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRADHPLIDLRLFRNPVLT 299
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML + + G ++DR+
Sbjct 300 HANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTVRLTGPLVDRQ 359
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVGI LI AGLG FAFGVARQA YLP L GLAI G+GMGC+MMPLS A+VQ L
Sbjct 360 GPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGLGMGCTMMPLSVASVQAL 419
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G
Sbjct 420 APHQIARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAGGTP 479
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+D S++PRQ+ F +LHDLSHAY VFVIA ALVV T+IPA+FLPK+ A+
Sbjct 480 IDQSAIPRQSLAPGFWGNVLHDLSHAYTAVFVIAVALVVCTIIPASFLPKKPATE 534
>gi|254818437|ref|ZP_05223438.1| hypothetical protein MintA_00852 [Mycobacterium intracellulare
ATCC 13950]
Length=540
Score = 696 bits (1797), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 357/530 (68%), Positives = 420/530 (80%), Gaps = 3/530 (0%)
Query 6 MVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVA 65
M EA A AP+P PAG+P + R YPD+LD LLR +GVC+LA+VMA +DVTVVSVA
Sbjct 1 MDEASYAAAGAPLPHAPAGQPGADTREYPDKLDAELLRISGVCILATVMAILDVTVVSVA 60
Query 66 QRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLC 125
QRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSVLAF LGSLLC
Sbjct 61 QRTFIDQFASSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVLAFMLGSLLC 120
Query 126 AVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPI 185
A+A NIL LIIFRVVQG GGGML P+ F IL REAGP RLGR+M+++ IPMLL P+GGPI
Sbjct 121 AIAANILQLIIFRVVQGVGGGMLLPLGFMILTREAGPARLGRLMSILSIPMLLAPIGGPI 180
Query 186 LGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFL 245
LGGWLI WRWIFL+N+P+GL +VLAAIVFPRD P SE FD +G+LLLSPGLA FL
Sbjct 181 LGGWLIDTSSWRWIFLINVPIGLLTIVLAAIVFPRDHPVRSETFDAVGVLLLSPGLAMFL 240
Query 246 FGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMT 305
F VSS P RGT+ADRHV+IPA GLALIA FVAH+W+R +HPLID+RLF+N + AN+T
Sbjct 241 FAVSSVPGRGTVADRHVVIPATIGLALIAGFVAHAWHRADHPLIDLRLFRNPVLTHANVT 300
Query 306 MTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKI 365
M V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+GP KI
Sbjct 301 MLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHLIPQGLGAMLTMRLTGPLVDRQGPGKI 360
Query 366 VLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQI 425
VLVGI+LI AGLG FAFGVA+QA YLP+L LA+ G+GMGC+MMPLS AAVQ LAPHQI
Sbjct 361 VLVGIVLITAGLGAFAFGVAKQAHYLPVLLVALAVTGLGMGCTMMPLSVAAVQALAPHQI 420
Query 426 ARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSS 485
ARG+TL+SVN QVGGS+GTALMS++LT QFN S+ I A KVA + G VD S+
Sbjct 421 ARGTTLMSVNHQVGGSMGTALMSMILTNQFNRSQNIVAANKVAALHQRATVDGVPVDQSA 480
Query 486 LPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+PRQ F ++HDLSHAY VFVIA LVV T+IPA+FLPK+ AS
Sbjct 481 IPRQALVPGFWGNVVHDLSHAYTAVFVIAVVLVVCTIIPASFLPKKPASE 530
>gi|296166469|ref|ZP_06848901.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295898230|gb|EFG77804.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=537
Score = 695 bits (1793), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 358/535 (67%), Positives = 422/535 (79%), Gaps = 5/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A + P+P PA + +R YPDRLD GLLR +GVC+LA+VMA +DVT
Sbjct 1 MLSNAMDEAPYAAAETPLPYAPA--LDADERDYPDRLDAGLLRISGVCILATVMAIIDVT 58
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVV WTMTGY LALATVIP GWAADRFGT+RLF+ SVLAFT+
Sbjct 59 VVSVAQRTFIDQFASSQAVVGWTMTGYTLALATVIPITGWAADRFGTKRLFIWSVLAFTM 118
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GS+LCA+A N+L LI FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 119 GSVLCALAANVLQLITFRVVQGVGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 178
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+ GPILGGWLI WRWIFL+NLP+GL +VLAA++FPRD PA SE FD +G+LLLSPG
Sbjct 179 IAGPILGGWLIDTSSWRWIFLINLPIGLVTIVLAAVIFPRDDPARSETFDLVGVLLLSPG 238
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VS+ P RGT+ADRHVLIPA GL LIAAFVAH+W+R +HPLID+RLF+N +
Sbjct 239 LATFLFAVSTVPGRGTVADRHVLIPAAIGLTLIAAFVAHAWHRADHPLIDLRLFRNPVLT 298
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQV HQ+PMQ+G+ +IPQGLGAML M + G ++DRR
Sbjct 299 HANVTMLVFATAFFGAGLLLPSYFQQVWHQTPMQAGLRMIPQGLGAMLTMRLTGPLVDRR 358
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVG+ LI AGLGTFA GVA QADYLP L GLAIMG+GMGC+MMPLS AAVQ L
Sbjct 359 GPGKVVLVGVALITAGLGTFAVGVATQADYLPTLLVGLAIMGLGMGCTMMPLSVAAVQAL 418
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS +LT QFN SE IA A K+A + A G
Sbjct 419 APHQIARGTTLMSVSHQVGGSVGTALMSTILTNQFNRSENIAAANKLAALQQHAAVSGVP 478
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
VD S++PRQT F LLHDLS AY VFVIA LVV T+IPA+FLPK+ AS
Sbjct 479 VDQSAIPRQTLSAGFWDSLLHDLSRAYTAVFVIAVVLVVFTIIPASFLPKKPASQ 533
>gi|254773668|ref|ZP_05215184.1| EmrB efflux protein [Mycobacterium avium subsp. avium ATCC 25291]
Length=560
Score = 693 bits (1788), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 356/535 (67%), Positives = 421/535 (79%), Gaps = 4/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A P P P G+P +R YPD+LD LLR +GVC+LA+VMA +DVT
Sbjct 23 MLSNAMDEAPYAAAKTP-PHAPTGQPGGTEREYPDKLDAALLRISGVCILATVMAILDVT 81
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSVLAF L
Sbjct 82 VVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVLAFML 141
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A NIL LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 142 GSLLCALAANILQLIVFRVVQGIGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 201
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI WRWIFL+N+P+GL + LAA+VFPRD PA SE FD +G+LLLSPG
Sbjct 202 IGGPILGGWLIDTSSWRWIFLINVPIGLVTVALAAVVFPRDHPARSETFDAVGVLLLSPG 261
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VSS P RGT+ADRHVLIPA GL LIA FV H+W+R +HPLID+RLF+N +
Sbjct 262 LATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRADHPLIDLRLFRNPVLT 321
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+
Sbjct 322 HANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQ 381
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVGI LI AGLG FAFGVARQA YLP L GLAI G+GMGC+MMPLS A+VQ L
Sbjct 382 GPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGLGMGCTMMPLSVASVQAL 441
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G
Sbjct 442 APHQIARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAGGTP 501
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+D S++PRQ+ F +LHDLSHAY VFVIA LVV T+IPA+FLPK+ A+
Sbjct 502 IDQSAIPRQSLAPGFWGNVLHDLSHAYTAVFVIAVVLVVCTIIPASFLPKKPATE 556
>gi|289756871|ref|ZP_06516249.1| LOW QUALITY PROTEIN: multidrug resistance integral membrane efflux
protein EmrB [Mycobacterium tuberculosis T85]
gi|289712435|gb|EFD76447.1| LOW QUALITY PROTEIN: multidrug resistance integral membrane efflux
protein EmrB [Mycobacterium tuberculosis T85]
Length=351
Score = 693 bits (1788), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 351/351 (100%), Positives = 351/351 (100%), Gaps = 0/351 (0%)
Query 190 LIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVS 249
LIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVS
Sbjct 1 LIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVS 60
Query 250 SSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVL 309
SSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVL
Sbjct 61 SSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVL 120
Query 310 SLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVG 369
SLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVG
Sbjct 121 SLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVG 180
Query 370 IMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGS 429
IMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGS
Sbjct 181 IMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGS 240
Query 430 TLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQ 489
TLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQ
Sbjct 241 TLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQ 300
Query 490 TNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 540
TNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
Sbjct 301 TNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA 351
>gi|16226140|gb|AAL16083.1|AF421382_1 EmrB efflux protein [Mycobacterium avium]
Length=538
Score = 688 bits (1775), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 354/535 (67%), Positives = 420/535 (79%), Gaps = 4/535 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML NAM EA A P P P G+P +R YPD+LD LLR +GVC+LA+VMA +DVT
Sbjct 1 MLSNAMDEAPYAAAKTP-PHAPTGQPGGTEREYPDKLDAALLRISGVCILATVMAILDVT 59
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLF+GSVLAF L
Sbjct 60 VVSVAQRTFIDQFSSSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFIGSVLAFML 119
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+A NIL LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P
Sbjct 120 GSLLCALAANILQLIVFRVVQGIGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAP 179
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI WRWIFL+N+P+GL + LAA+VFPRD PA SE FD +G+LLLSPG
Sbjct 180 IGGPILGGWLIDTSSWRWIFLINVPIGLLTVALAAVVFPRDHPARSETFDAVGVLLLSPG 239
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLF VSS P RGT+ADRHVLIPA GL LIA FV H+W+R +HPLID+RLF+N +
Sbjct 240 LATFLFAVSSIPGRGTVADRHVLIPAAMGLTLIAGFVGHAWHRADHPLIDLRLFRNPVLT 299
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
AN+TM V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+
Sbjct 300 HANVTMLVFATAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQ 359
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VLVGI LI AGLG FAFGVARQA YLP L GLAI G+GMGC+M+P S A+VQ L
Sbjct 360 GPGKVVLVGIALITAGLGAFAFGVARQAPYLPTLLAGLAITGLGMGCTMVPQSVASVQAL 419
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQIARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G
Sbjct 420 APHQIARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPNIVAANKLAALHQKAAAGGTP 479
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+D S++PRQ+ F +LHDLSHAY VFVIA LVV T+IPA+FLPK+ A+
Sbjct 480 IDQSAIPRQSLAPGFWGNVLHDLSHAYTAVFVIAVVLVVCTIIPASFLPKKPATE 534
>gi|240173126|ref|ZP_04751784.1| integral membrane drug efflux protein [Mycobacterium kansasii
ATCC 12478]
Length=531
Score = 683 bits (1763), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 339/508 (67%), Positives = 408/508 (81%), Gaps = 3/508 (0%)
Query 28 SGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGY 87
+GQRS+ D+LD LLR AGVCVL S+M+ VD TVV+VAQRTFVA F +TQA+VAWTMTGY
Sbjct 18 TGQRSHTDQLDARLLRIAGVCVLGSMMSIVDTTVVTVAQRTFVATFHTTQAMVAWTMTGY 77
Query 88 MLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGM 147
LALA VIP AGW ADRFGT+R FMGS+LAFT GSLLCA+APNI LL++FRVVQG GGGM
Sbjct 78 TLALAAVIPLAGWVADRFGTKRPFMGSLLAFTFGSLLCAMAPNITLLVVFRVVQGLGGGM 137
Query 148 LTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVG 207
L P+ IL REAGP+RLGRV+A++GIPMLLGPV GP+LGGWLI +YGW+WIF +NLP+G
Sbjct 138 LMPLVLTILTREAGPRRLGRVLAILGIPMLLGPVFGPVLGGWLIDSYGWQWIFWINLPIG 197
Query 208 LSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAI 267
L L+LAA VFP D+P SE+FD +G+LLLSPGLATFL+GVS PARGT+ DRHV IPA
Sbjct 198 LITLLLAATVFPGDQPTPSESFDVLGMLLLSPGLATFLYGVSVVPARGTVTDRHVWIPAA 257
Query 268 TGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQV 327
GLALI FV H+ YR EHPLID+RLF NR VA AN M + ++ FG+ LL PSY Q++
Sbjct 258 LGLALIVGFVLHASYRAEHPLIDLRLFTNRVVALANSAMFLFAVSFFGAGLLFPSYFQEL 317
Query 328 LHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQ 387
LHQ+P+ +G+ ++P+G+GAM+ MP+AG+MMD+RGP KI+LVG+ LIAAG+G FA+GVARQ
Sbjct 318 LHQTPLGAGMSMVPRGIGAMVTMPLAGSMMDKRGPGKILLVGVTLIAAGMGIFAYGVARQ 377
Query 388 ADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALM 447
A YLP L GL IMG+GMG +MMPLS AAVQTLAPH IARGSTL+SVNQQVG S+GTALM
Sbjct 378 AAYLPTLLIGLTIMGLGMGLTMMPLSAAAVQTLAPHHIARGSTLVSVNQQVGASVGTALM 437
Query 448 SVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQT---NFAAQLLHDLSHAY 504
S++LT QFN SE +A A+K+A E A RG VDPSS+P Q +F +LHDLSHAY
Sbjct 438 SMILTSQFNRSENVAAARKIADLQEDAARRGVPVDPSSIPPQALNPDFKGNVLHDLSHAY 497
Query 505 AVVFVIATALVVSTLIPAAFLPKQQASH 532
+VVF A LV TL+P AFLPK+ A
Sbjct 498 SVVFAAAVGLVALTLVPVAFLPKKPAGQ 525
>gi|342862172|ref|ZP_08718814.1| EmrB efflux protein [Mycobacterium colombiense CECT 3035]
gi|342130250|gb|EGT83570.1| EmrB efflux protein [Mycobacterium colombiense CECT 3035]
Length=534
Score = 682 bits (1759), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 347/530 (66%), Positives = 415/530 (79%), Gaps = 3/530 (0%)
Query 6 MVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVA 65
M EA A P+P G+P +R YPD+LD LLR +GVC+LA+VMA +DVTVVSVA
Sbjct 1 MDEASYAAAKTPLPHATTGQPGVEEREYPDKLDTALLRISGVCILATVMAILDVTVVSVA 60
Query 66 QRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLC 125
QRTF+ F S+QAVVAWTMTGY LALATVIP GWAADRFGT+RLFMGSV+AF LGSLLC
Sbjct 61 QRTFIDQFASSQAVVAWTMTGYTLALATVIPITGWAADRFGTKRLFMGSVVAFILGSLLC 120
Query 126 AVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPI 185
AVA NIL LI+FRVVQG GGGML P+ F IL REAGP+RLGR+M+++ IPMLL P+GGPI
Sbjct 121 AVAANILQLIVFRVVQGVGGGMLLPLGFMILTREAGPRRLGRLMSILSIPMLLAPIGGPI 180
Query 186 LGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFL 245
LGGWLI WRWIFL+N+P+G + LAAI+FPRD PA SE FD +G+LLLSPGLA FL
Sbjct 181 LGGWLIDTSSWRWIFLINVPIGFLTIALAAIIFPRDHPARSETFDAVGVLLLSPGLAMFL 240
Query 246 FGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMT 305
F VSS P RGT+ADRHV +PA GL+LIA FVAH+W +HPLID+RLF+N + AN+T
Sbjct 241 FAVSSIPGRGTVADRHVAVPAAIGLSLIAGFVAHAWRHADHPLIDLRLFRNPVLTHANVT 300
Query 306 MTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKI 365
M V + FG+ LLLPSY QQVLHQ+PMQ+GVH+IPQGLGAML M + G ++DR+GP KI
Sbjct 301 MLVFAGAFFGAGLLLPSYFQQVLHQTPMQAGVHMIPQGLGAMLTMRLTGPLVDRQGPGKI 360
Query 366 VLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQI 425
VLVGI LI AGL FA+GVA Q+ YLP+L GLAIMG+GMGC+MMPLS A+VQ LAPHQI
Sbjct 361 VLVGIALITAGLSAFAYGVATQSHYLPLLLVGLAIMGLGMGCTMMPLSVASVQALAPHQI 420
Query 426 ARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSS 485
ARG+TL+SV+ QVGGS+GTALMS++LT QFN S I A K+A + A G VDP++
Sbjct 421 ARGTTLMSVSHQVGGSMGTALMSMILTNQFNRSPDIVAANKLAALHQKAAADGVPVDPAA 480
Query 486 LPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
+PRQ+ F + ++HDLSHAY VFVIA LVV T IPA+FLPK+ AS
Sbjct 481 IPRQSLDPGFLSNVVHDLSHAYTAVFVIAVVLVVCTFIPASFLPKKPASE 530
>gi|240172330|ref|ZP_04750989.1| integral membrane drug efflux protein [Mycobacterium kansasii
ATCC 12478]
Length=538
Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 365/533 (69%), Positives = 425/533 (80%), Gaps = 3/533 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML +AM +A A DA +P T G+ G+ YPDRLD L R AGVCVLASVM +D T
Sbjct 1 MLSSAMDKARSAPADAALPTTATGQHSPGEHVYPDRLDARLFRIAGVCVLASVMTILDAT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
+VSVAQRTF+ +F STQAVV WTMTGY LALATVIP GWAADRFGT+RL+MGS+LAFTL
Sbjct 61 IVSVAQRTFITEFDSTQAVVGWTMTGYTLALATVIPLTGWAADRFGTKRLWMGSILAFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+APNIL LI FRV+QG GGGML P+ F IL R AGPKRLGR+MAV+GIPMLLGP
Sbjct 121 GSLLCALAPNILALIAFRVIQGIGGGMLMPLGFTILTRVAGPKRLGRMMAVLGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLIGA+ W WIFLVNLP+GL A LAAIVFP+DRPA +E+FD +G+LLLSPG
Sbjct 181 IGGPILGGWLIGAFSWPWIFLVNLPIGLIAFTLAAIVFPKDRPAPAESFDLVGVLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSS P RG++ DR+V +P I GL L+A F H+W+R +HPL+D+RLF NR A
Sbjct 241 LATFLFGVSSIPGRGSVTDRYVAVPVIVGLMLVALFGWHAWHRADHPLLDLRLFTNRVFA 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
+AN+T + FG+ LLLPSYLQQVLHQ+PMQSGVH+IP GLGAML MP AGA MDRR
Sbjct 301 RANLTFVTFAAAYFGAALLLPSYLQQVLHQTPMQSGVHLIPNGLGAMLTMPFAGAFMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K VLVG+ LIAAGLG FAFGVARQ YLP L GL ++GMG G +MMPLSGAA+Q L
Sbjct 361 GPGKSVLVGLTLIAAGLGIFAFGVARQTGYLPTLLVGLLVLGMGTGATMMPLSGAAIQAL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
AP +IARGS +ISV QQVGGSIGTALMS++LT QFN SE I A K+A + +G A
Sbjct 421 APREIARGSAVISVTQQVGGSIGTALMSMILTNQFNRSENIGAANKIAALQQQAVRQGVA 480
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQA 530
VDPS++P+Q +FA+++LHDLSHAY VVFVIA LVVSTLIPAAFLPK A
Sbjct 481 VDPSAIPQQALAHDFASRVLHDLSHAYTVVFVIAVVLVVSTLIPAAFLPKTPA 533
>gi|183984873|ref|YP_001853164.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
gi|183178199|gb|ACC43309.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
Length=539
Score = 666 bits (1718), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 360/534 (68%), Positives = 415/534 (78%), Gaps = 3/534 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML AM EA + P T G G+ YPDRLD GLLR AGVCVLAS+M+ +D T
Sbjct 1 MLSTAMDEAHCTPAEVAPPDTRTGTSSPGEHVYPDRLDAGLLRIAGVCVLASLMSVLDAT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VV VAQRTF+ +F STQAVVAWTMTGY LALATVIP AGWAADRFGT+RL+MGSVLAF L
Sbjct 61 VVGVAQRTFIIEFDSTQAVVAWTMTGYTLALATVIPVAGWAADRFGTKRLWMGSVLAFAL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+APNIL LI FRV+QG GGGML P+ F IL R AGPKRLGR+MA +GIPMLLGP
Sbjct 121 GSLLCALAPNILSLIFFRVLQGVGGGMLMPLGFIILTRAAGPKRLGRLMAAIGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI ++GW WIFLVNLP+GL+A LAAI FP DRP SE+FD +G+LLLSPG
Sbjct 181 IGGPILGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSESFDVIGVLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LA FL G+S P RGT+ADR+VLIP I GL+LI F H+W+R +HPLID+ LF N V
Sbjct 241 LAAFLLGLSLIPDRGTVADRYVLIPVIAGLSLIGGFAWHAWHRADHPLIDLHLFNNSVVT 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QAN+T+ + FGS LL+P+YLQQVLHQ+PMQSG+++IPQGLGAML MPIA A MDRR
Sbjct 301 QANLTLLAFAAAYFGSSLLIPTYLQQVLHQTPMQSGLYLIPQGLGAMLTMPIASAFMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K VL+GI+LIA GL F FGVA +A YLP L GLAIMGMG GC+MMPL+GAAV TL
Sbjct 361 GPGKSVLLGIVLIAVGLAMFTFGVATRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
P +IARGSTLISV QQVGGSIGTALM+ +LT QFN S+ I A KVA ++ A RG
Sbjct 421 KPREIARGSTLISVTQQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAARGVT 480
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
VDPS LP Q +FA ++HDLSHAY VVF +A LVVSTLIPAAFLPK A+
Sbjct 481 VDPSGLPPQALTPDFADNVMHDLSHAYTVVFGVAVVLVVSTLIPAAFLPKTPAA 534
>gi|296166470|ref|ZP_06848902.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295898231|gb|EFG77805.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=537
Score = 651 bits (1679), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 324/531 (62%), Positives = 404/531 (77%), Gaps = 5/531 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAM +A DAPVP G+ + +R YPD+LD L R A VC +A++MA +D T
Sbjct 1 MLGNAMQKADSVTSDAPVPSAATGQSNADERQYPDKLDAALFRVAAVCGMATIMALLDTT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTF A FGST AVV+WTM GYMLALATVIP GWA DRFGT+RLF+G+V FTL
Sbjct 61 VVSVAQRTFAAQFGSTLAVVSWTMAGYMLALATVIPVTGWAVDRFGTKRLFVGAVFLFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+APNIL LI+FRVVQG GGGML P+S IL REAGP+RLGR++A+ GIP++L P
Sbjct 121 GSLLCALAPNILALIMFRVVQGLGGGMLMPLSSMILTREAGPQRLGRLIAIGGIPLVLAP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+G PILGGW+I YGW WIFL+NLP+G++ +VLAAI+FPRDRP SE D++G LLLSPG
Sbjct 181 IGAPILGGWVIDTYGWEWIFLINLPIGITTIVLAAILFPRDRPEPSEALDFIGALLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
+A FL GVSS P R T+ADR+VLIP I GL LI AFV H+WYRT+HPLID+RL +NR V
Sbjct 241 VAIFLGGVSSIPGRHTVADRYVLIPVIIGLVLITAFVFHAWYRTDHPLIDLRLLKNRVVT 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QAN+T+ V ++G G+ L LPSY Q V++++PMQS + ++PQ LGA L MP+AG D+R
Sbjct 301 QANLTLLVFTVGYVGAGLTLPSYFQLVMNETPMQSAMRLVPQALGAALTMPLAGIYADKR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K+VL+G+ LIAAGL FA GVAR ADYLP L GLAIMG+G+GC+ PL A VQ L
Sbjct 361 GPGKVVLIGLPLIAAGLAIFAVGVARHADYLPTLLVGLAIMGLGIGCTTAPLGAAVVQAL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
AP QIARG+TL+SVN ++ SIG ALM+V++T Q + ++II A K A P + G+G +
Sbjct 421 APQQIARGTTLVSVNLEMSSSIGAALMAVIVTTQISRNDII--AGKAASLPSNVGGQGPS 478
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQ 528
D + RQ + A+ LL++LSHAY VFV+A ALV T+IPAAFLPK+
Sbjct 479 ADATGAARQALPPDVASALLNNLSHAYTTVFVLAVALVTFTIIPAAFLPKR 529
>gi|118616342|ref|YP_904674.1| integral membrane drug efflux protein [Mycobacterium ulcerans
Agy99]
gi|118568452|gb|ABL03203.1| integral membrane drug efflux protein [Mycobacterium ulcerans
Agy99]
Length=553
Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 356/534 (67%), Positives = 412/534 (78%), Gaps = 3/534 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML AM EA + P T G G+ YPDRLD GLLR AGVCVLAS+M+ +D T
Sbjct 1 MLSTAMDEAHCTPAEVAPPDTRTGTSSPGEHVYPDRLDAGLLRIAGVCVLASLMSVLDAT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VV +AQRTF+ +F STQAVVAWTMTGY LALATVIP AGWAADRFGT+RL+MGSVLAF L
Sbjct 61 VVGIAQRTFIIEFDSTQAVVAWTMTGYTLALATVIPVAGWAADRFGTKRLWMGSVLAFAL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCA+APNIL LI FRV+QG GGGML P+ F IL R AGPKRLGR+MA +GIPMLLGP
Sbjct 121 GSLLCALAPNILSLIFFRVLQGVGGGMLMPLGFIILTRAAGPKRLGRLMAAIGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLI ++GW WIFLVNLP+GL+A LAAI FP DRP SE+FD +G+LLLSPG
Sbjct 181 IGGPILGGWLISSFGWHWIFLVNLPIGLAAFALAAITFPADRPVPSESFDVIGVLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LA FL +S P RGT+ADR+VLIP I GL+LI F H+W+R +HPLID+ LF N V
Sbjct 241 LAAFLLALSLIPDRGTVADRYVLIPVIAGLSLIGGFAWHAWHRADHPLIDLHLFNNSVVT 300
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
QAN+T+ + FGS LL+P+YLQQVLHQ+PMQSG+++IPQGLGAML MPIA A MDRR
Sbjct 301 QANLTLLAFAAAYFGSSLLIPTYLQQVLHQTPMQSGLYLIPQGLGAMLTMPIASAFMDRR 360
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP K VL+GI+LIA GL F FGVA +A YLP L GLAIMGMG GC+MMPL+GAAV TL
Sbjct 361 GPGKSVLLGIVLIAVGLAMFTFGVATRAQYLPTLLVGLAIMGMGTGCTMMPLAGAAVLTL 420
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
P +IARGSTLISV QQVGGSIGTALM+ +LT QFN S+ I A KVA ++ A RG
Sbjct 421 KPREIARGSTLISVTQQVGGSIGTALMATILTNQFNRSDNIWVANKVATLEQNAAARGVT 480
Query 481 VDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
VDPS LP Q +FA ++HDLSHAY VVF + LVVSTLIPAA LPK A+
Sbjct 481 VDPSGLPPQALTPDFADNVMHDLSHAYTVVFGVVVVLVVSTLIPAASLPKTPAA 534
>gi|289568735|ref|ZP_06448962.1| multidrug resistance membrane efflux protein emrB [Mycobacterium
tuberculosis T17]
gi|289542489|gb|EFD46137.1| multidrug resistance membrane efflux protein emrB [Mycobacterium
tuberculosis T17]
Length=354
Score = 637 bits (1644), Expect = 1e-180, Method: Compositional matrix adjust.
Identities = 322/322 (100%), Positives = 322/322 (100%), Gaps = 0/322 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT
Sbjct 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL
Sbjct 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP
Sbjct 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG
Sbjct 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
Sbjct 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
Query 301 QANMTMTVLSLGLFGSFLLLPS 322
QANMTMTVLSLGLFGSFLLLPS
Sbjct 301 QANMTMTVLSLGLFGSFLLLPS 322
>gi|183982530|ref|YP_001850821.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
gi|183175856|gb|ACC40966.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
Length=529
Score = 613 bits (1580), Expect = 3e-173, Method: Compositional matrix adjust.
Identities = 321/514 (63%), Positives = 391/514 (77%), Gaps = 3/514 (0%)
Query 26 PRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMT 85
P +GQ+ D+LD LL+ AGVCVL S+MA VD TVV+VAQRTFV+ F S QA+VAWTMT
Sbjct 2 PDTGQQGSSDQLDARLLKIAGVCVLGSMMAIVDTTVVTVAQRTFVSTFDSPQAIVAWTMT 61
Query 86 GYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGG 145
GY LALA VIP AGW ADRFGT+R F+ S+LAF+ GSLLCA+APNI LI FRV+QG GG
Sbjct 62 GYTLALAAVIPLAGWVADRFGTKRPFIASLLAFSAGSLLCALAPNISALIAFRVIQGLGG 121
Query 146 GMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLP 205
GML P+ +L REAGP RLGRV+AV+GIPMLLGPV GP+LGGWLI +GW WIF +NLP
Sbjct 122 GMLMPLVLTMLTREAGPARLGRVLAVLGIPMLLGPVFGPVLGGWLIDRFGWEWIFWINLP 181
Query 206 VGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIP 265
+GL + LAA+VFP+DRP SE+FD +G+LLLSPGLATFL+GVS+ PA GT+ADRHV +P
Sbjct 182 IGLITVGLAAVVFPKDRPEPSESFDVIGMLLLSPGLATFLYGVSALPASGTIADRHVWLP 241
Query 266 AITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQ 325
A GL LI FV H+ YR +HPLID+RLF NR V AN+ M + + FG+ LL PSY Q
Sbjct 242 AAVGLVLIGGFVLHALYRADHPLIDLRLFDNRVVTLANVAMFLFAASFFGAGLLFPSYFQ 301
Query 326 QVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVA 385
++L Q+PMQ+G+ ++P+GLGAM+ MPIAGA+MD+RG KI++VG+ LIAAG+G FA GV+
Sbjct 302 ELLGQTPMQAGMSMVPRGLGAMVTMPIAGALMDKRGAGKILMVGVGLIAAGMGLFAIGVS 361
Query 386 RQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTA 445
A YLP L TGL IMG+GMG +MMPLS AVQTL PHQIARGSTLI+VNQQV SIGTA
Sbjct 362 LNAAYLPTLVTGLTIMGLGMGATMMPLSAVAVQTLTPHQIARGSTLINVNQQVAASIGTA 421
Query 446 LMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQT---NFAAQLLHDLSH 502
LMSV+LT QFN S I+ A ++ A G VD S +P + +F L+HDLSH
Sbjct 422 LMSVILTSQFNRSANISAAHRIDSLRADAARSGVPVDQSLMPERASTPDFPLVLMHDLSH 481
Query 503 AYAVVFVIATALVVSTLIPAAFLPKQQASHRRAP 536
AYAVVFV+A LV +P AFLPK+ + RR P
Sbjct 482 AYAVVFVVAVGLVALMFVPVAFLPKKPPAVRRNP 515
>gi|342862173|ref|ZP_08718815.1| EmrB efflux protein [Mycobacterium colombiense CECT 3035]
gi|342130251|gb|EGT83571.1| EmrB efflux protein [Mycobacterium colombiense CECT 3035]
Length=537
Score = 606 bits (1563), Expect = 3e-171, Method: Compositional matrix adjust.
Identities = 330/534 (62%), Positives = 405/534 (76%), Gaps = 5/534 (0%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML AM + A P+P P + + YPD+LD L R AGVC LA +MA +D T
Sbjct 1 MLSGAMQKTRSAAFSVPLPSAPGSSLHADE--YPDKLDAALFRIAGVCGLACIMAVLDST 58
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VV+VAQRTF+A FGSTQA+V+WT+ GYMLA ATVIP GWAADRFGT+RLFMGSVL FTL
Sbjct 59 VVAVAQRTFIAQFGSTQAIVSWTIAGYMLAFATVIPITGWAADRFGTKRLFMGSVLIFTL 118
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLI+FRV+QG GGGML P+SF IL REAGPKR+GR+MAV GIP+LLGP
Sbjct 119 GSLLCAVAPNILLLILFRVIQGVGGGMLLPLSFVILTREAGPKRVGRLMAVGGIPILLGP 178
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLIGAYGW+WIFLVNLP+GL+A LAA++FP+DR A SE D G LLLSPG
Sbjct 179 IGGPILGGWLIGAYGWKWIFLVNLPIGLTAFALAAVMFPKDRSAPSEALDITGALLLSPG 238
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
+A FL GV S P R T+ADR+VL+PA+ GL LIAAF+ H+WYRT+HPLID+RLF+N V
Sbjct 239 VAIFLCGVCSIPGRHTIADRYVLVPALLGLVLIAAFILHAWYRTDHPLIDLRLFRNPVVT 298
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
Q N+T+ V G LL+PS+ Q V H++PMQSG+H++P G+GA+L MP+ GA MD+R
Sbjct 299 QVNVTLLVFGAASVGIGLLVPSFFQIVGHETPMQSGLHMLPIGIGAVLTMPLGGAFMDKR 358
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP IVL+G+ L+ GLG F +GVARQA Y P+L TGLAIMG+G+G + PLS A +Q L
Sbjct 359 GPGNIVLIGLPLMTVGLGVFTYGVARQAAYSPVLVTGLAIMGLGIGLTTTPLSAALMQAL 418
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAA 480
APHQ+ARG+TLISVNQQVGGSIG ALM+V+LT QFN +E + A ++ G
Sbjct 419 APHQVARGTTLISVNQQVGGSIGAALMAVVLTNQFNRNETLMAANEMGGVRPGAGKHGLP 478
Query 481 VDPSSLPRQ---TNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
DPS+LPRQ + A+ + H L+HAY VFV+A LV T+IPA+FLPK+ S
Sbjct 479 ADPSALPRQPLAPDLASHVSHHLAHAYTAVFVLAVVLVAFTIIPASFLPKKPPS 532
>gi|183980128|ref|YP_001848419.1| integral membrane efflux protein ErmB [Mycobacterium marinum
M]
gi|183173454|gb|ACC38564.1| integral membrane efflux protein ErmB [Mycobacterium marinum
M]
Length=557
Score = 587 bits (1513), Expect = 2e-165, Method: Compositional matrix adjust.
Identities = 299/506 (60%), Positives = 373/506 (74%), Gaps = 4/506 (0%)
Query 28 SGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGY 87
+G+R + DRLD LLR AG+CV ASV ++ T VSVAQR+ + FGS QAVVAWT+T Y
Sbjct 29 AGER-HVDRLDGSLLRIAGICVFASVAVNLANTAVSVAQRSLIVTFGSNQAVVAWTVTAY 87
Query 88 MLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGM 147
L A IP +GWAADR GT+RLFM SVL FTLGS+LCAVAPNI LIIFR VQG GGG+
Sbjct 88 TLTEAAAIPLSGWAADRIGTKRLFMISVLGFTLGSVLCAVAPNIACLIIFRAVQGGGGGI 147
Query 148 LTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVG 207
L P+ ILAREAGP RL R+M+V+GIP+LLGP+ GPILGGWLI YGW+WIF +N+P+G
Sbjct 148 LMPLVITILAREAGPNRLARLMSVMGIPLLLGPMAGPILGGWLIDDYGWQWIFWINVPIG 207
Query 208 LSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAI 267
L + LAAI FP D A SE D +G+LLLSPGLATFL+G+S+ PARGT+ADRHVLIPA
Sbjct 208 LITVALAAIAFPGDHTAPSETLDIIGMLLLSPGLATFLYGLSTVPARGTVADRHVLIPAT 267
Query 268 TGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQV 327
GL L+ AFV H+ YR + PLID+RLF+NR V AN T+ ++ G G+ LL+PSY QQ+
Sbjct 268 AGLVLMGAFVFHALYRADRPLIDLRLFRNRVVTVANATIVFVAAGFSGAVLLVPSYFQQL 327
Query 328 LHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQ 387
L ++P+Q G+H+IP GLGA + +P + +MDR G K+VL G+ LI+ G+GT AFG A
Sbjct 328 LRETPLQVGIHMIPLGLGAAVTIPTSSVLMDRHGAGKVVLGGVTLISVGMGTLAFGAAEH 387
Query 388 ADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALM 447
A Y+P L GL I+GMG+G M+ L+ AVQTLAPHQIARGSTL+SVNQQ+ S TALM
Sbjct 388 AAYVPTLLIGLTIVGMGIGSIMLQLTTVAVQTLAPHQIARGSTLVSVNQQLSASASTALM 447
Query 448 SVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQT---NFAAQLLHDLSHAY 504
SV+LT QFN S IA A ++ ES RG +DPS +P +T +F A LLHDLS AY
Sbjct 448 SVILTSQFNRSANIAAANRLEALNESATRRGIPLDPSQIPPRTLNPDFGANLLHDLSQAY 507
Query 505 AVVFVIATALVVSTLIPAAFLPKQQA 530
VVFV A+ +++ T +PA FLP + A
Sbjct 508 TVVFVYASVVMLVTFLPAVFLPMRAA 533
>gi|118465955|ref|YP_880004.1| EmrB efflux protein [Mycobacterium avium 104]
gi|118167242|gb|ABK68139.1| EmrB efflux protein [Mycobacterium avium 104]
gi|336458305|gb|EGO37284.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium
avium subsp. paratuberculosis S397]
Length=537
Score = 586 bits (1510), Expect = 4e-165, Method: Compositional matrix adjust.
Identities = 327/518 (64%), Positives = 399/518 (78%), Gaps = 5/518 (0%)
Query 18 VPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQ 77
VP+ A P YPD+LD L R AGVC LA +MA +D TVV+VAQRTF+A FG+ Q
Sbjct 16 VPLATASGPSLRDDEYPDKLDAALFRIAGVCGLACIMAVLDSTVVAVAQRTFIAQFGANQ 75
Query 78 AVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIF 137
A+V+WT+ GYMLA ATVIP GWAADRFGT+RLFMGSVL FTLGSLLCAVAPNILLLI+F
Sbjct 76 AIVSWTIAGYMLAFATVIPITGWAADRFGTKRLFMGSVLIFTLGSLLCAVAPNILLLILF 135
Query 138 RVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWR 197
RVVQG GGGML P+SF IL REAGPKR+GR+MAV GIP+LLGP+GGPILGGWLIGAYGW+
Sbjct 136 RVVQGVGGGMLLPLSFVILTREAGPKRVGRLMAVGGIPILLGPIGGPILGGWLIGAYGWK 195
Query 198 WIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTM 257
WIFL+NLP+GL+A LAA++FP+DR A SE D G LLLSPG+A FL GV S P R T+
Sbjct 196 WIFLINLPIGLTAFALAALLFPKDRSAPSEALDITGALLLSPGVAIFLCGVCSIPGRHTV 255
Query 258 ADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSF 317
ADR+VL+PA+ GL LIAAF+ H+WYRTEHPLID+RLF+N V Q N+T+ V + G
Sbjct 256 ADRYVLVPALVGLVLIAAFILHAWYRTEHPLIDLRLFRNPVVTQVNVTLLVFAAASVGVG 315
Query 318 LLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGL 377
LL+PSY Q V H++PMQSG+H++P G+GA+L MP+ GA+MD+ GP KIVL G+ L+A GL
Sbjct 316 LLVPSYFQIVGHETPMQSGLHMLPIGVGAVLTMPLGGAVMDKHGPGKIVLTGLPLMAVGL 375
Query 378 GTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQ 437
F +GVARQA Y P+L GLAIMG+G+G + PLS A +Q LAPHQ+ARG+TLISVNQQ
Sbjct 376 AVFTYGVARQAAYSPVLVCGLAIMGLGIGLTTTPLSAALMQALAPHQVARGTTLISVNQQ 435
Query 438 VGGSIGTALMSVLLTYQFNHSEIIATAKKVA-LTPESGAGRGAAVDPSSLPR---QTNFA 493
VGGSIG ALM+V+LT QFN + + A + A + P +G RG VDPS++PR A
Sbjct 436 VGGSIGAALMAVILTNQFNRNPALMAANEAAGMHPVTGK-RGLPVDPSTVPRPAMTPELA 494
Query 494 AQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
+ H LSHAY VFV+A LV T+IPA+FLP++ S
Sbjct 495 GHVSHHLSHAYTAVFVLAVVLVACTIIPASFLPRKPPS 532
>gi|41406716|ref|NP_959552.1| hypothetical protein MAP0618c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41395066|gb|AAS02935.1| hypothetical protein MAP_0618c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=537
Score = 585 bits (1507), Expect = 9e-165, Method: Compositional matrix adjust.
Identities = 327/518 (64%), Positives = 398/518 (77%), Gaps = 5/518 (0%)
Query 18 VPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQ 77
VP+ A P YPD+LD L R AGVC LA +MA +D TVV+VAQRTF+A FG Q
Sbjct 16 VPLATASGPSLRDDEYPDKLDAALFRIAGVCGLACIMAVLDSTVVAVAQRTFIAQFGVNQ 75
Query 78 AVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIF 137
A+V+WT+ GYMLA ATVIP GWAADRFGT+RLFMGSVL FTLGSLLCAVAPNILLLI+F
Sbjct 76 AIVSWTIAGYMLAFATVIPITGWAADRFGTKRLFMGSVLIFTLGSLLCAVAPNILLLILF 135
Query 138 RVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWR 197
RVVQG GGGML P+SF IL REAGPKR+GR+MAV GIP+LLGP+GGPILGGWLIGAYGW+
Sbjct 136 RVVQGVGGGMLLPLSFVILTREAGPKRVGRLMAVGGIPILLGPIGGPILGGWLIGAYGWK 195
Query 198 WIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTM 257
WIFL+NLP+GL+A LAA++FP+DR A SE D G LLLSPG+A FL GV S P R T+
Sbjct 196 WIFLINLPIGLTAFALAALLFPKDRSAPSEALDITGALLLSPGVAIFLCGVCSIPGRHTV 255
Query 258 ADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSF 317
ADR+VL+PA+ GL LIAAF+ H+WYRTEHPLID+RLF+N V Q N+T+ V + G
Sbjct 256 ADRYVLVPALVGLVLIAAFILHAWYRTEHPLIDLRLFRNPVVTQVNVTLLVFAAASVGVG 315
Query 318 LLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGL 377
LL+PSY Q V H++PMQSG+H++P G+GA+L MP+ GA+MD+ GP KIVL G+ L+A GL
Sbjct 316 LLVPSYFQIVGHETPMQSGLHMLPIGVGAVLTMPLGGAVMDKHGPGKIVLTGLPLMAVGL 375
Query 378 GTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQ 437
F +GVARQA Y P+L GLAIMG+G+G + PLS A +Q LAPHQ+ARG+TLISVNQQ
Sbjct 376 AVFTYGVARQAAYSPVLVCGLAIMGLGIGLTTTPLSAALMQALAPHQVARGTTLISVNQQ 435
Query 438 VGGSIGTALMSVLLTYQFNHSEIIATAKKVA-LTPESGAGRGAAVDPSSLPR---QTNFA 493
VGGSIG ALM+V+LT QFN + + A + A + P +G RG VDPS++PR A
Sbjct 436 VGGSIGAALMAVILTNQFNRNPALMAANEAAGMHPVTGK-RGLPVDPSTVPRPAMTPELA 494
Query 494 AQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
+ H LSHAY VFV+A LV T+IPA+FLP++ S
Sbjct 495 GHVSHHLSHAYTAVFVLAVVLVACTIIPASFLPRKPPS 532
>gi|254773667|ref|ZP_05215183.1| EmrB efflux protein [Mycobacterium avium subsp. avium ATCC 25291]
Length=520
Score = 580 bits (1496), Expect = 1e-163, Method: Compositional matrix adjust.
Identities = 325/513 (64%), Positives = 395/513 (77%), Gaps = 5/513 (0%)
Query 23 AGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAW 82
A P YPD+LD L R AGVC LA +MA +D TVV+VAQRTF+A FG+ QA+V+W
Sbjct 4 ASGPSLRDDEYPDKLDAALFRIAGVCGLACIMAVLDSTVVAVAQRTFIAQFGANQAIVSW 63
Query 83 TMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQG 142
T+ GYMLA ATVIP GWAADRFGT+RLFMGSVL FTLGSLLCAVAPNILLLI+FRVVQG
Sbjct 64 TIAGYMLAFATVIPITGWAADRFGTKRLFMGSVLIFTLGSLLCAVAPNILLLILFRVVQG 123
Query 143 FGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLV 202
GGGML P+SF IL REAGPKR+GR+MAV GIP+LLGP+GGPILGGWLIGAYGW+WIFL+
Sbjct 124 VGGGMLLPLSFVILTREAGPKRVGRLMAVGGIPILLGPIGGPILGGWLIGAYGWKWIFLI 183
Query 203 NLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHV 262
NLP+GL+A LAA++FP+DR A SE D G LLLSPG+A FL GV S P R T+ADR+V
Sbjct 184 NLPIGLTAFALAALLFPKDRSAPSEALDITGALLLSPGVAIFLCGVCSIPGRHTVADRYV 243
Query 263 LIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPS 322
L+PA+ GL LIAAF+ H+WYRTEHPLID+RLF+N V Q N+T+ V + G LL+PS
Sbjct 244 LVPALVGLVLIAAFILHAWYRTEHPLIDLRLFRNPVVTQVNVTLLVFAAASVGVGLLVPS 303
Query 323 YLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAF 382
Y Q V H++PMQSG+H++P G+GA+L MP+ GA+MD+ GP KIVL G+ L+A GL F +
Sbjct 304 YFQIVGHETPMQSGLHMLPIGVGAVLTMPLGGAVMDKHGPGKIVLTGLPLMAVGLAVFTY 363
Query 383 GVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSI 442
GVARQA Y P+L GLAIMG+G+G + PLS A +Q LAPHQ+ARG+TLISVNQQVGGSI
Sbjct 364 GVARQAAYSPVLVCGLAIMGLGIGLTTTPLSAALMQALAPHQVARGTTLISVNQQVGGSI 423
Query 443 GTALMSVLLTYQFNHSEIIATAKKVA-LTPESGAGRGAAVDPSSLPRQT---NFAAQLLH 498
G ALM+V+LT QFN + + A + A + P +G RG VDPS+ PR A + H
Sbjct 424 GAALMAVILTNQFNRNPALMAANEAAGMHPVTGK-RGLPVDPSAAPRPAMTPELAGHVSH 482
Query 499 DLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
LSHAY VFV+A LV T+IPA+FLP++ S
Sbjct 483 HLSHAYTAVFVLAVVLVACTIIPASFLPRKPPS 515
>gi|254818438|ref|ZP_05223439.1| EmrB efflux protein [Mycobacterium intracellulare ATCC 13950]
Length=536
Score = 578 bits (1490), Expect = 8e-163, Method: Compositional matrix adjust.
Identities = 328/535 (62%), Positives = 404/535 (76%), Gaps = 9/535 (1%)
Query 1 MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVT 60
ML AM A P+PI P P YPD+LD L R AGVC LA +MA +D T
Sbjct 1 MLSGAMENTRSASFTVPLPIEPG--PSRHPDEYPDKLDAALFRIAGVCGLACIMAVLDST 58
Query 61 VVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTL 120
VV+VAQRTF+ FGSTQAVV+WT+ GYMLA ATVIP GWAADRFGT+RLFMGSVL FTL
Sbjct 59 VVAVAQRTFIDQFGSTQAVVSWTIAGYMLAFATVIPITGWAADRFGTKRLFMGSVLIFTL 118
Query 121 GSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGP 180
GSLLCAVAPNILLLI+FRVVQG GGGML P+SF IL REAGPKR+GR+MAV GIP+LLGP
Sbjct 119 GSLLCAVAPNILLLILFRVVQGVGGGMLLPLSFVILTREAGPKRVGRLMAVGGIPILLGP 178
Query 181 VGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPG 240
+GGPILGGWLIGAYGW+WIFL+NLP+GL+A LAAI+F +DR A SE D G LLLSPG
Sbjct 179 IGGPILGGWLIGAYGWKWIFLINLPIGLTAFALAAIMFAKDRSAPSEALDITGALLLSPG 238
Query 241 LATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA 300
+A FL GV S P R T+ D +VL PA+ GLALI AF+ H+W+RT+HPLID+RLF+N V
Sbjct 239 VAIFLCGVCSIPGRHTITDPYVLGPALLGLALIGAFIVHAWHRTDHPLIDLRLFRNPVVT 298
Query 301 QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRR 360
+ N+TM V G LL+PSY Q V H++PMQSG+H++P G+GA+L MPI GA MD+
Sbjct 299 EVNVTMLVFGAASVGVGLLIPSYFQIVSHETPMQSGLHMLPIGIGAVLTMPIGGAFMDKH 358
Query 361 GPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTL 420
GP IVL+G+ L+AAGLG F +GVA QA+Y P+L +GLAIMG+G G + PLS A +Q L
Sbjct 359 GPGNIVLIGLPLMAAGLGVFTYGVATQAEYSPVLVSGLAIMGLGAGLTTTPLSAALMQAL 418
Query 421 APHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVA-LTPESGAGRGA 479
P Q+ARG+TLISVNQQVGGSIG ALM+V+LT QFN +E + A ++A + P +G
Sbjct 419 TPRQVARGTTLISVNQQVGGSIGAALMAVILTNQFNRNEALMAANEMAGVRPPAGK---R 475
Query 480 AVDPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
++DPS+LP QT + A+ + H L+HAY VFV+A LV T++PA+FLP++ A+
Sbjct 476 SIDPSALPGQTMTPDLASHVSHHLAHAYTTVFVLAVVLVAFTVVPASFLPRRLAT 530
>gi|183983099|ref|YP_001851390.1| integral membrane drug efflux protein, ErmB_1 [Mycobacterium
marinum M]
gi|183176425|gb|ACC41535.1| integral membrane drug efflux protein, ErmB_1 [Mycobacterium
marinum M]
Length=533
Score = 573 bits (1476), Expect = 3e-161, Method: Compositional matrix adjust.
Identities = 286/502 (57%), Positives = 366/502 (73%), Gaps = 3/502 (0%)
Query 30 QRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYML 89
Q +YPDRLD +R AGVC++A++MA++D+++V+VAQRTF F STQA VAWT+ GYML
Sbjct 19 QDNYPDRLDWPTIRIAGVCLIAAIMANLDISIVTVAQRTFTVAFHSTQATVAWTVAGYML 78
Query 90 ALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLT 149
+AT P GWAADR G +RLFMG+V FTLGS+LCA APNI LLI FRVVQG GGG+L
Sbjct 79 GMATATPMTGWAADRLGAKRLFMGAVATFTLGSMLCASAPNIGLLITFRVVQGIGGGVLG 138
Query 150 PVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLS 209
P+ AI+ +AGP+RLGR++AV IPML P+ GPILGGWLI +YGW+WIFL+N+P GL
Sbjct 139 PLVLAIVTHQAGPRRLGRLLAVGAIPMLTAPMLGPILGGWLIDSYGWQWIFLINVPAGLL 198
Query 210 ALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITG 269
A LAAI+ P D P SE FD++G+LLL PG+A L GVS+ P GT+ D V +PAI+G
Sbjct 199 AFGLAAILVPEDPPKPSERFDFIGMLLLLPGIAMLLLGVSAIPGSGTVTDHRVWVPAISG 258
Query 270 LALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLH 329
LI AF H+WYRT+HPLID+RLF +R V AN+ + + G G+ LLLPSY QQ+LH
Sbjct 259 AVLITAFALHAWYRTDHPLIDLRLFTDRVVRLANLALLLYVAGAAGASLLLPSYFQQLLH 318
Query 330 QSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQAD 389
Q+PM+SG+ ++P G GAML MP+ GA MD RGP K+VL+G+ LIAAG GTF FGVA +AD
Sbjct 319 QTPMRSGLMMVPIGFGAMLTMPLTGAFMDSRGPRKVVLIGLTLIAAGTGTFVFGVANEAD 378
Query 390 YLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSV 449
YLP L GL I GMG+GC+ + L+ + ++ LAPHQIARGS LISVNQQ+ GSIG ALMS+
Sbjct 379 YLPTLLAGLTIAGMGLGCTGLLLAASVMRVLAPHQIARGSALISVNQQISGSIGAALMSM 438
Query 450 LLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQT---NFAAQLLHDLSHAYAV 506
+LT QF S I+TA +A+ E+ + PS++P + +F +L HDLSHAY +
Sbjct 439 ILTNQFCRSHTISTANNMAVLRENAERHVVPIAPSAVPARAVGPDFLVELQHDLSHAYTL 498
Query 507 VFVIATALVVSTLIPAAFLPKQ 528
F +A L PAAFLP +
Sbjct 499 TFAVAAVLGALAYFPAAFLPAK 520
>gi|183982968|ref|YP_001851259.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
gi|183176294|gb|ACC41404.1| integral membrane drug efflux protein [Mycobacterium marinum
M]
Length=559
Score = 559 bits (1440), Expect = 5e-157, Method: Compositional matrix adjust.
Identities = 303/513 (60%), Positives = 378/513 (74%), Gaps = 14/513 (2%)
Query 19 PITPAGRPRS-GQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQ 77
P +P P + Q SYPDRLD GL R AGVCVL S+M VD +VV+VAQRTFV FGSTQ
Sbjct 10 PRSPDTHPDNRHQHSYPDRLDAGLWRIAGVCVLGSIMTMVDTSVVTVAQRTFVDTFGSTQ 69
Query 78 AVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIF 137
AVVAWT+TGY LALA V+P AGWAADRFGT+R+FMGS+L FTL SLLCA+APNI LLI
Sbjct 70 AVVAWTITGYTLALAAVVPLAGWAADRFGTKRMFMGSILVFTLSSLLCAIAPNIALLIAS 129
Query 138 RVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWR 197
RVVQG GGGML P++ I+ REAGPKR+GRVMAV+GIP +L P GP LGGWLI +Y W+
Sbjct 130 RVVQGLGGGMLAPLALTIVNREAGPKRVGRVMAVLGIPGVLAPAFGPALGGWLIDSYSWQ 189
Query 198 WIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTM 257
WIF VNLPVG+ A+ LAA+VFPRD PA SE FD +G+LLLSPGL FL+G+S P GT+
Sbjct 190 WIFWVNLPVGVVAVGLAAVVFPRDTPAPSETFDVVGMLLLSPGLPAFLYGMSEIPIYGTV 249
Query 258 ADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSF 317
ADRHV +PA G+ALI F+ H+ YR + PLID+RL NRA+ AN+ M + + FG+
Sbjct 250 ADRHVWVPAGIGIALIVGFMFHALYRADKPLIDLRLLTNRALTLANVAMFLYIVSTFGAG 309
Query 318 LLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGL 377
+L PSY QQ+L +P+Q+G+ ++P+G+GA LA+P+AGA++DRRG ++++G+ LIA G+
Sbjct 310 VLFPSYFQQLLDHTPLQAGMSLLPRGIGAALAVPLAGALVDRRGARGVLVIGVTLIATGM 369
Query 378 GTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQ 437
G FAFGVA Q DYLP+L GL I+GMGMGC+ MPL A+Q+LAP+QIARGSTLI VNQQ
Sbjct 370 GVFAFGVATQRDYLPMLLIGLTILGMGMGCTRMPLVAVAMQSLAPNQIARGSTLIKVNQQ 429
Query 438 VGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLL 497
+ ++GTALMSV+LT Q N+ E + A K + E G P P +L
Sbjct 430 MAAAVGTALMSVILTSQLNNGENASGASKAEILREHRPGV-----PLDQP--------VL 476
Query 498 HDLSHAYAVVFVIATALVVSTLIPAAFLPKQQA 530
H+LS AY+VVFV+A L V IP AFLPK A
Sbjct 477 HELSRAYSVVFVVAVVLAVLAFIPLAFLPKWSA 509
>gi|240168038|ref|ZP_04746697.1| integral membrane drug efflux protein [Mycobacterium kansasii
ATCC 12478]
Length=480
Score = 480 bits (1235), Expect = 3e-133, Method: Compositional matrix adjust.
Identities = 263/491 (54%), Positives = 340/491 (70%), Gaps = 39/491 (7%)
Query 54 MAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMG 113
M +D TVV+VAQRTFV FGSTQAVV+WT+TGY LALA VIP GWAADRFGT+R+F+G
Sbjct 1 MNLLDTTVVTVAQRTFVTTFGSTQAVVSWTITGYTLALAAVIPLTGWAADRFGTKRIFIG 60
Query 114 SVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVG 173
SV+AFTLGSLLCAVAPNI LLII RV+QGFGGG+LT ++ I+ REAGP+R+GRVMAV+G
Sbjct 61 SVVAFTLGSLLCAVAPNITLLIISRVLQGFGGGILTTLTLTIVNREAGPRRVGRVMAVLG 120
Query 174 IPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMG 233
IPM+L P GP+LGGWLI +Y W+WIF +NLPVG+ A+ LAAIV P D A SE FD +G
Sbjct 121 IPMVLAPAFGPVLGGWLIDSYSWQWIFWINLPVGVVAIGLAAIVLPDDDSAPSETFDVIG 180
Query 234 LLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRL 293
+LLLSPGL L+G+S P RGT+ D HV IP G ALI FV H+ YR++ PLID+RL
Sbjct 181 MLLLSPGLPVLLYGMSEIPNRGTVTDGHVWIPLAVGTALIVGFVFHALYRSDKPLIDLRL 240
Query 294 FQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIA 353
NRA N+ M + FG+ +L PSY QQ+L+Q+P+Q+G+ ++P+G+GA ++MP+A
Sbjct 241 LTNRAFTLTNVAMFFYIVSTFGAGVLFPSYFQQLLNQTPLQAGMSVVPRGIGAAVSMPLA 300
Query 354 GAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLS 413
G +MDRRG ++++G+ L AG+G FA+GVA Q + L +L GL ++G+GMG + MPL
Sbjct 301 GTLMDRRGARGVLVIGVALNVAGMGVFAYGVAHQRESLLLLLAGLTMLGLGMGSTRMPLV 360
Query 414 GAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPES 473
A+QTLAP Q+ARGST++ VNQQV ++GTAL+SV+LT Q H +++
Sbjct 361 AVAMQTLAPDQMARGSTMVKVNQQVAAAVGTALLSVILTGQL-HQPVMS----------- 408
Query 474 GAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFL-------- 525
L R DLSHAY V+A LV T IP AFL
Sbjct 409 ----------QQLSRS---------DLSHAYTAALVVAVVLVGLTFIPLAFLYQRPKAMV 449
Query 526 PKQQASHRRAP 536
P+ +SHR P
Sbjct 450 PRHTSSHRITP 460
>gi|312140993|ref|YP_004008329.1| mfs transporter [Rhodococcus equi 103S]
gi|325675370|ref|ZP_08155054.1| MFS family major facilitator transporter [Rhodococcus equi ATCC
33707]
gi|311890332|emb|CBH49650.1| putative MFS transporter [Rhodococcus equi 103S]
gi|325553341|gb|EGD23019.1| MFS family major facilitator transporter [Rhodococcus equi ATCC
33707]
Length=503
Score = 470 bits (1210), Expect = 2e-130, Method: Compositional matrix adjust.
Identities = 256/499 (52%), Positives = 337/499 (68%), Gaps = 27/499 (5%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D++D +L+ A V VL ++M+ +DVTVVSVA TF F ++ AVVAWTMT Y LALATV
Sbjct 18 DKIDGAVLKIASVVVLGAIMSILDVTVVSVALPTFAETFETSYAVVAWTMTAYTLALATV 77
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IP GWAADRFGT+RL++G+++ F +GS+LCA A +I LI+FRV+QG GGGML P+
Sbjct 78 IPVTGWAADRFGTKRLYIGALVLFVIGSVLCAFAWDITSLIVFRVIQGLGGGMLMPLGMT 137
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
I+ R AGP+R+GRVMAV+GIPMLLGP+ GPI+GGWLI A W WIFL+NLP+G+ AL A
Sbjct 138 IMTRAAGPERVGRVMAVLGIPMLLGPIAGPIVGGWLIDAASWHWIFLINLPIGIIALAAA 197
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
+ P+D P+ S++FD++G+LLLSPGLA FL+GVSS P G VLIP GL LI
Sbjct 198 FKLLPKDEPSPSQSFDFVGMLLLSPGLALFLYGVSSIPEHGKGLSPEVLIPIGIGLVLII 257
Query 275 AFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQ 334
FV H+ R +HPLID+ LFQNR + A +T T+ + G+ LL PSY QV +S M
Sbjct 258 GFVFHA-LRKDHPLIDLHLFQNRQLTVAVLTTTMFIIAFMGAGLLFPSYFIQVRGESAMA 316
Query 335 SGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPIL 394
+G+ + PQG+GAM+ MPIAG ++D+ GP KIVL G+ LIA LG F F P+L
Sbjct 317 AGLLLAPQGIGAMVTMPIAGRLVDKIGPGKIVLTGLPLIA--LGMFTFTQLTATSSYPLL 374
Query 395 PTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQ 454
L +MG+GMGC+MMPL AA+ TL IARGSTL+++ QQ GSIGTA MSV+LT Q
Sbjct 375 MGSLFVMGLGMGCTMMPLMTAAMVTLKHEMIARGSTLMNIVQQTAGSIGTATMSVVLTNQ 434
Query 455 FNHSEIIATAKKVALTPESGAGRGAA--VDPSSLPRQTNFAAQLLHDLSHAYAVVFVIAT 512
G + AA DPSS+ AQ+L+D + ++ F++A
Sbjct 435 MT---------------SHGLSKDAAPPTDPSSV-------AQMLNDSADSFGATFMVAF 472
Query 513 ALVVSTLIPAAFLPKQQAS 531
LV+ TLIPA FLP+++ +
Sbjct 473 VLVLVTLIPAFFLPRKRVA 491
>gi|183984924|ref|YP_001853215.1| multidrug resistance integral membrane efflux protein [Mycobacterium
marinum M]
gi|183178250|gb|ACC43360.1| multidrug resistance integral membrane efflux protein [Mycobacterium
marinum M]
Length=545
Score = 467 bits (1202), Expect = 2e-129, Method: Compositional matrix adjust.
Identities = 263/527 (50%), Positives = 343/527 (66%), Gaps = 7/527 (1%)
Query 11 PAEGDAPVPITPAGRPRSGQRSYPD----RLDVGLLRTAGVCVLASVMAHVDVTVVSVAQ 66
P E + AG R G PD RLD LL T C++ VM +D TVV+VAQ
Sbjct 9 PREPEIGASTHAAGESRLGDDGRPDAHPVRLDAELLMTTATCLMLPVMVTLDTTVVNVAQ 68
Query 67 RTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCA 126
RTF+ +F STQAVVAWT TGY L+LA+VIP GWAA+R GT+RL MGSVL FTLGSLLCA
Sbjct 69 RTFIEEFSSTQAVVAWTSTGYTLSLASVIPLTGWAANRLGTKRLVMGSVLLFTLGSLLCA 128
Query 127 VAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPIL 186
+A +I LL+ FR QG GGG+L P+ ILAR AGP RLGRV+ + I +L+ P+ GPIL
Sbjct 129 MASSITLLVAFRAAQGLGGGILIPLQLIILARAAGPARLGRVLTISMISVLMAPIAGPIL 188
Query 187 GGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLF 246
GGWLI A+GW+WIFL+NLP+G L+LA +V P D +E+ D +G+ LLSP L L+
Sbjct 189 GGWLIDAFGWQWIFLINLPIGALTLILAGLVLPGDDSLPAESLDLVGMALLSPALVLLLY 248
Query 247 GVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTM 306
G+S+ PARGT+ D V +P GL LI F H+ +R +H LID+RL +NRAVA AN T
Sbjct 249 GLSALPARGTIGDPQVWLPTTVGLILIGGFALHALHRGDHALIDLRLLKNRAVAAANATR 308
Query 307 TVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIV 366
+ ++ FGS LL P+Y QQVL ++P+QSG+ +IPQ L A MPI G +M++RGP +V
Sbjct 309 FMFAVTFFGSCLLFPAYFQQVLGKTPLQSGLLLIPQTLAAAAVMPIVGRLMEKRGPRDVV 368
Query 367 LVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIA 426
L+G L G+G F +G++R+ +LP L GL G+G M+P+S +AV L ++A
Sbjct 369 LMGTALTVVGMGIFIYGMSREHVHLPALLIGLGTFGVGTAAMMVPVSWSAVHMLNSSEVA 428
Query 427 RGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSL 486
GSTL +VN V S+G ALMSV+LT +FN S IA A + E + +D S+L
Sbjct 429 HGSTLFNVNHNVAASVGAALMSVVLTSRFNGSADIAAANRADEIREQALRQHLPLDVSNL 488
Query 487 P---RQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQA 530
P R FA L DLS AYA VF++ +V +T IPA FLPK+ A
Sbjct 489 PPRIRTPGFAEHLTKDLSLAYAGVFLLGMIVVATTAIPAWFLPKRPA 535
>gi|54024315|ref|YP_118557.1| putative transporter [Nocardia farcinica IFM 10152]
gi|54015823|dbj|BAD57193.1| putative transporter [Nocardia farcinica IFM 10152]
Length=464
Score = 462 bits (1189), Expect = 7e-128, Method: Compositional matrix adjust.
Identities = 252/495 (51%), Positives = 335/495 (68%), Gaps = 36/495 (7%)
Query 47 VCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFG 106
+ VL ++M+ +DVTVV+VA TF+ +F +T A+ AWTMTGY LALATVIP GWAADRFG
Sbjct 1 MVVLGAIMSILDVTVVTVALPTFITEFETTYAIAAWTMTGYTLALATVIPITGWAADRFG 60
Query 107 TRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLG 166
T+RL++ ++ F LGSLLC+VA NI LI FRV+QG GGGML P+ I+ AGP+R+G
Sbjct 61 TKRLYLMALTFFVLGSLLCSVAWNIESLIAFRVIQGLGGGMLMPLGMTIMTHAAGPQRIG 120
Query 167 RVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAAS 226
RVMAV+G+PMLLGP+ GPILGGWLI A+ W WIFL+NLP+G+ +LVLA +V P D P S
Sbjct 121 RVMAVLGVPMLLGPITGPILGGWLIDAFSWHWIFLINLPIGIVSLVLAYLVLPADEPQPS 180
Query 227 ENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEH 286
E+FD++G+LL SPGLA FL+GVS+ P GT+AD VL+PA G+ L+ FV H+ RTEH
Sbjct 181 ESFDFLGMLLASPGLALFLYGVSTIPETGTVADAKVLVPAAIGVLLLVGFVFHA-LRTEH 239
Query 287 PLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGA 346
PLID+ LF+NRA+ + +TM + ++ FG+ LLLPSYLQQV +S M +G+ + PQG+GA
Sbjct 240 PLIDLHLFRNRALTFSVLTMVLFAIAFFGAGLLLPSYLQQVRGESAMAAGLLMAPQGIGA 299
Query 347 MLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMG 406
ML MPIAG +DR GP KIV+VGI +I + F + Q Y+ L L +MG+GMG
Sbjct 300 MLTMPIAGRFVDRIGPGKIVMVGIAVITVSM-VFFVQLTDQTSYVA-LCAALFVMGLGMG 357
Query 407 CSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKK 466
C+MMP+ AA+QTL Q+ARGSTL+++ Q GSIGTA MSV+L+ +
Sbjct 358 CTMMPIMTAAIQTLTHQQVARGSTLMNIINQTAGSIGTATMSVVLSNEMKE--------- 408
Query 467 VALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLP 526
SG P+ LP A A++ +V+A L TLIPA FLP
Sbjct 409 -----RSG--------PAGLPGPAEAA--------EAFSNTYVVALVLAGLTLIPAFFLP 447
Query 527 KQQASHRR---APLL 538
+ + + + AP+L
Sbjct 448 RTRPAATQDADAPML 462
>gi|326329297|ref|ZP_08195622.1| drug transporter [Nocardioidaceae bacterium Broad-1]
gi|325952872|gb|EGD44887.1| drug transporter [Nocardioidaceae bacterium Broad-1]
Length=535
Score = 459 bits (1181), Expect = 6e-127, Method: Compositional matrix adjust.
Identities = 253/522 (49%), Positives = 343/522 (66%), Gaps = 23/522 (4%)
Query 30 QRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYML 89
+++ D LD +L AGV VL S+M+ +D+TVVSVA TF +F +T A VAWTMTGY L
Sbjct 9 EKAPDDHLDKSVLIVAGVVVLGSIMSILDITVVSVALETFQREFDATSAEVAWTMTGYTL 68
Query 90 ALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLT 149
ALATVIP GWAADRFGT+RL+M +++ F LGS LCA+A ++ +L+ FRV+QG GGGML
Sbjct 69 ALATVIPLTGWAADRFGTKRLYMTAIVLFALGSALCALATSLPMLVAFRVIQGLGGGMLM 128
Query 150 PVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLS 209
P+ IL R AGP+R+GRVMA++G+PMLLGP+ GPI+GG LI + W WIFL+N+P+G+
Sbjct 129 PLGMTILTRAAGPERVGRVMAILGVPMLLGPILGPIIGGALIDSASWHWIFLINIPIGVV 188
Query 210 ALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITG 269
A++ A P+D S++FD++G++LLSPGLA FL+GVSS P GT+ D VL + G
Sbjct 189 AIIYAWRALPKDHVEPSQSFDFLGMVLLSPGLALFLYGVSSIPEAGTILDTKVLSFMVAG 248
Query 270 LALIAAFVAHSWY-RTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVL 328
L LIAAF+ + R +HPLID+RLF N+ + A +T+++ ++ FG+ LL P Y QQV
Sbjct 249 LVLIAAFIPWALSARNDHPLIDVRLFGNKELTVAVITLSIFAMAFFGASLLFPLYYQQVR 308
Query 329 HQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQA 388
+ + +G+ + PQGLGAM+ MP+AG + DR GP KIVL G+ IA G+ F +R
Sbjct 309 GEDALHAGLLLAPQGLGAMVTMPLAGMLADRTGPGKIVLSGLTTIAVGM----FMFSRLD 364
Query 389 DYLP--ILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTAL 446
D P L L IMG+GMG +MMP AA TL H IARG+TL+++ QQV S GTAL
Sbjct 365 DATPYWYLLVSLFIMGLGMGATMMPTFAAAQATLREHTIARGTTLVNIVQQVAASAGTAL 424
Query 447 MSVLLTYQFNHSEIIATAKKVA--LTPESGAGRGAAVDPSSLPRQTNFAAQLLHD----- 499
SVLLT + E I+ A +A L +G DP++ + AA L D
Sbjct 425 FSVLLTNALSGKESISAADDLADKLGVPAGGLEKFLADPANQQKVGEAAASLGLDPAKLP 484
Query 500 ---------LSHAYAVVFVIATALVVSTLIPAAFLPKQQASH 532
++ A++ FVIA LV++TLIPA FLPK +A H
Sbjct 485 EVFKAIPVEMAEAFSTTFVIAAILVLATLIPAWFLPKSKAEH 526
>gi|240170021|ref|ZP_04748680.1| multidrug resistance integral membrane efflux protein [Mycobacterium
kansasii ATCC 12478]
Length=553
Score = 458 bits (1179), Expect = 9e-127, Method: Compositional matrix adjust.
Identities = 273/542 (51%), Positives = 350/542 (65%), Gaps = 22/542 (4%)
Query 19 PITPAGRP-RSGQR-----------SYPD-----RLDVGLLRTAGVCVLASVMAHVDVTV 61
P T A P RS QR + PD RLD LL C++ +M +D TV
Sbjct 12 PTTVASTPARSQQRLDDDARTGGSPAVPDPGPDCRLDSRLLLITVTCMMLPLMVTLDTTV 71
Query 62 VSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLG 121
V+VAQRTF+ +F S QAVVAW TGY LALA VIP GW A+R GT+RL M SVL FT G
Sbjct 72 VNVAQRTFIEEFASDQAVVAWASTGYTLALAAVIPLTGWLANRLGTKRLLMASVLMFTAG 131
Query 122 SLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPV 181
SLLCA+A NI LL+ FR VQGFGGGML P+ ILAR AGP RLGRVM + I +LL P+
Sbjct 132 SLLCALASNIALLVAFRAVQGFGGGMLLPLQLIILARAAGPARLGRVMTISMITVLLAPI 191
Query 182 GGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGL 241
GPILGGWLI ++GW+WIFL+NLP+G+ LVLA + PRD +E+ D +G++LLSPGL
Sbjct 192 AGPILGGWLIDSFGWQWIFLINLPIGVLTLVLAVVTLPRDDSLPAESLDLVGMVLLSPGL 251
Query 242 ATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQ 301
L+GVS P RGT+AD HV +PA G+ LI AFVAH+ RT+ LID+RL + R+VA
Sbjct 252 VLLLYGVSQLPERGTVADPHVWVPATMGVLLIGAFVAHALRRTDCVLIDLRLLKYRSVAA 311
Query 302 ANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRG 361
AN T + ++ FGS LL P+Y QQVL ++PMQSG+ +IPQ + A +PI G +M+ RG
Sbjct 312 ANATRFLFAVTFFGSCLLFPAYFQQVLGKTPMQSGLLLIPQTVAAAAVIPIVGRLMESRG 371
Query 362 PAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLA 421
P +VLVGI + G+ FA + RQ L +L +GL + G+G C M+P++ +AVQTL
Sbjct 372 PRSVVLVGIAVTVVGMAMFAHAIRRQGADLTVLLSGLGLFGLGTACLMVPVTWSAVQTLD 431
Query 422 PHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAV 481
++A GSTL +VN V S+GTALMSV+LT +FN S IA A++ E A RG +
Sbjct 432 SSEVAHGSTLFNVNHNVAASVGTALMSVILTSRFNGSAAIAAARQADSVREHAARRGLSA 491
Query 482 DPSSLPRQT---NFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLL 538
D S LP +F QL DL+ +Y+ VF +A L IPA+FLPK+ R LL
Sbjct 492 DLSKLPSPVLAPHFHEQLADDLALSYSGVFGVAMVLTAMIAIPASFLPKRATP--RVKLL 549
Query 539 SA 540
A
Sbjct 550 EA 551
>gi|258650304|ref|YP_003199460.1| EmrB/QacA subfamily drug resistance transporter [Nakamurella
multipartita DSM 44233]
gi|258553529|gb|ACV76471.1| drug resistance transporter, EmrB/QacA subfamily [Nakamurella
multipartita DSM 44233]
Length=541
Score = 452 bits (1164), Expect = 5e-125, Method: Compositional matrix adjust.
Identities = 249/529 (48%), Positives = 339/529 (65%), Gaps = 20/529 (3%)
Query 8 EACPAEGDAPVP--------ITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDV 59
E +G AP P PA P + D+LD + R AGV VL ++M+ +DV
Sbjct 9 EPGAVDGSAPPPQLTKNQLTKNPAPTPVAADD---DKLDGTVWRIAGVVVLGAIMSILDV 65
Query 60 TVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFT 119
TVVSVA TF F ++ A VAWTMTGY LALATVIP GWAADRFGT+RL+M ++ F
Sbjct 66 TVVSVALPTFQTTFDASYATVAWTMTGYTLALATVIPLTGWAADRFGTKRLYMLALTLFL 125
Query 120 LGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLG 179
LGS+ C +A +I LI FRV+QG GGGML P+ I+ AGP R+GRVMAV+G+PMLLG
Sbjct 126 LGSIACGLAWSIESLIAFRVLQGLGGGMLMPLGMTIMTHAAGPHRIGRVMAVLGVPMLLG 185
Query 180 PVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSP 239
P+ GPILGGWLI W WIF +N+P+G+ AL+ A V +D P+ SE+FD++G+LLLSP
Sbjct 186 PIFGPILGGWLIETASWHWIFFINVPIGIVALIAAWRVLAKDEPSPSESFDFVGMLLLSP 245
Query 240 GLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAV 299
GLA FLFGVS+ P GT A V+IP + GL L+ FV H+ R +HPLID+ LF+ + +
Sbjct 246 GLALFLFGVSTIPEEGTFASAKVIIPLVVGLLLMTGFVFHALRRQDHPLIDLHLFKRKQM 305
Query 300 AQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDR 359
+ + +TM++ ++ FG+ LLLP+Y QV +S + +G+ + PQG+GAML MPIAG + D+
Sbjct 306 SVSVITMSLFAIAFFGAMLLLPTYFIQVREESTLTAGLLLAPQGIGAMLTMPIAGRLTDK 365
Query 360 RGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQT 419
GP K V+ G+ LI G+ F +P+L L I G+GMG +MMP+ AA+ T
Sbjct 366 MGPGKFVITGLFLILIGMSVFT--QISSTTPIPLLLGALFINGLGMGMTMMPIMTAALAT 423
Query 420 LAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGA 479
L ++ARGSTL+++ QQ S+GTA+MSV+LT QF I AK P + A
Sbjct 424 LRHAEVARGSTLMNIVQQSAASVGTAVMSVILTNQFLSKPAIQAAKAAQENPAAMAN--- 480
Query 480 AVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQ 528
V P L + AQ+ ++ A+ F +A A++V TLIPA LP++
Sbjct 481 -VPPDVLAQAK---AQVQEQMAEAFGTTFWVALAILVVTLIPAFMLPRK 525
>gi|226305233|ref|YP_002765191.1| drug resistance efflux protein [Rhodococcus erythropolis PR4]
gi|229490674|ref|ZP_04384512.1| multidrug resistance transporter, MFS family [Rhodococcus erythropolis
SK121]
gi|226184348|dbj|BAH32452.1| putative drug resistance efflux protein [Rhodococcus erythropolis
PR4]
gi|229322494|gb|EEN88277.1| multidrug resistance transporter, MFS family [Rhodococcus erythropolis
SK121]
Length=510
Score = 434 bits (1117), Expect = 1e-119, Method: Compositional matrix adjust.
Identities = 259/498 (53%), Positives = 338/498 (68%), Gaps = 13/498 (2%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D+LD +L+ A V VL ++M+ +DVTVVSVA TF DF ++ A VAWTMT Y LALATV
Sbjct 12 DKLDGAVLKIASVVVLGAIMSILDVTVVSVALTTFAEDFETSYATVAWTMTAYTLALATV 71
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IP GWAADRFGT+RL+M +++ F LGS+ CA+A +I LI FRV+QG GGGML P+
Sbjct 72 IPVTGWAADRFGTKRLYMTALVLFVLGSVACAMAWDITSLIGFRVLQGLGGGMLMPLGMT 131
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
I+ R AGP R+GRVMAV+GIPMLLGP+GGPILGGWLI A W WIFL+NLP+G+ AL A
Sbjct 132 IMTRAAGPDRVGRVMAVLGIPMLLGPIGGPILGGWLIEAASWHWIFLINLPIGIIALAAA 191
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
I+ P D+ SE+FD++G++LLSPGLA FLFGVSS P GT+A VL+ A GLALI
Sbjct 192 FIILPSDKAKPSESFDFLGMILLSPGLALFLFGVSSIPEVGTVASARVLVSAGIGLALII 251
Query 275 AFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQ 334
AFV H+ + +HPLID+ LF+NR + A +T ++ + G+ LL PSY QV + +
Sbjct 252 AFVFHALNK-DHPLIDLHLFKNRQLTTAVITTSLFIVAFMGAGLLFPSYFIQVGGHTTLA 310
Query 335 SGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPIL 394
+G+ + PQGLGAM+ MPIAG ++D+ GP KIVL G+ LI GLG F + +L L
Sbjct 311 AGLLMAPQGLGAMVTMPIAGRLVDKIGPGKIVLTGLPLILIGLGVFTQVASDSPTWL--L 368
Query 395 PTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQ 454
L +MG+GMGC+MMPL AA+ TL+ QIARGSTL+++ QQ GSIGTA+MSV+LT Q
Sbjct 369 MGALFVMGLGMGCTMMPLMTAAIVTLSNEQIARGSTLMNIVQQTAGSIGTAVMSVVLTNQ 428
Query 455 FNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATAL 514
+ T GA +P S Q + A +L S A+ F++AT L
Sbjct 429 LLDRGLDTTMV--------GAASHIPTEPGS--PQESAANSILSAASDAFGNTFLVATVL 478
Query 515 VVSTLIPAAFLPKQQASH 532
+V TLIPA FLP+ + +
Sbjct 479 IVLTLIPAFFLPRSKTTR 496
>gi|302867480|ref|YP_003836117.1| EmrB/QacA subfamily drug resistance transporter [Micromonospora
aurantiaca ATCC 27029]
gi|315506112|ref|YP_004084999.1| EmrB/QacA subfamily drug resistance transporter [Micromonospora
sp. L5]
gi|302570339|gb|ADL46541.1| drug resistance transporter, EmrB/QacA subfamily [Micromonospora
aurantiaca ATCC 27029]
gi|315412731|gb|ADU10848.1| drug resistance transporter, EmrB/QacA subfamily [Micromonospora
sp. L5]
Length=529
Score = 427 bits (1099), Expect = 2e-117, Method: Compositional matrix adjust.
Identities = 249/515 (49%), Positives = 343/515 (67%), Gaps = 32/515 (6%)
Query 36 RLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVI 95
+LD +L+ AGV VL ++M+ +DVTVVSVA TF ++F +T A VAWTMTGY LALATVI
Sbjct 11 KLDAAVLKVAGVVVLGAIMSILDVTVVSVALPTFQSEFDATYARVAWTMTGYTLALATVI 70
Query 96 PTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAI 155
P +GWAADRFGT+RL+M ++ FT+GS LCA A +I LI +RV+QG GGGML P+ I
Sbjct 71 PLSGWAADRFGTKRLYMVALALFTIGSGLCATADSIGELIAWRVIQGLGGGMLMPLGMTI 130
Query 156 LAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAA 215
+ R AGP R+GR+MAV+GIPMLLGP+ GPILGGWLI W WIFL+NLP+G+ ALV A
Sbjct 131 MTRAAGPHRIGRLMAVLGIPMLLGPITGPILGGWLIDVASWHWIFLINLPIGVVALVYAQ 190
Query 216 IVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAA 275
+ P+D SE+FD++G+L+LSPGLA FL+G+S+ P GT+AD V +P + G AL+ A
Sbjct 191 LALPKDNAEPSESFDFLGMLMLSPGLALFLYGISTLPETGTVADTKVWLPMLAGGALVVA 250
Query 276 FVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQS 335
FV +S +R HPL+D+RLF+NR + A +TM V + G+ LL PSY QV ++ + +
Sbjct 251 FVLYS-FRPRHPLLDLRLFRNRNLTIATVTMFVFIIAFMGAGLLFPSYFLQVRGETTLTA 309
Query 336 GVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILP 395
G+ I PQG+GAML MPIAG + DR + V ++LIAAG TF + Y +L
Sbjct 310 GLLIAPQGIGAMLTMPIAGMLADRVPVGRTVPFALVLIAAGFFTFT-QLGTDTSYW-LLC 367
Query 396 TGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQF 455
L +MG+GMG +MMP+ +A++TL+ ++ARGSTL+++ QQ+GGS+G A+MSV+LT +
Sbjct 368 GSLFVMGLGMGGTMMPIMTSALKTLSAAEVARGSTLVNILQQIGGSVGAAVMSVILTSEL 427
Query 456 NHSEIIATAKKVALTPESGAGRGAA-----------------VDPSSLPRQTNFAAQLLH 498
N S I P +GA A V PS + R ++AA
Sbjct 428 NGSRPIPGVTD----PATGAPLTEAQLAIASQQQPELTQQFPVPPSLIERGLDYAA---- 479
Query 499 DLSHAYAVVFVIATALVVSTLIPAAFLP-KQQASH 532
++++ F +A LV+ T IPAAFLP +++ SH
Sbjct 480 ---NSFSTTFWVAFGLVLLTFIPAAFLPRRREPSH 511
>gi|302530134|ref|ZP_07282476.1| elloramycin permease [Streptomyces sp. AA4]
gi|302439029|gb|EFL10845.1| elloramycin permease [Streptomyces sp. AA4]
Length=514
Score = 422 bits (1085), Expect = 7e-116, Method: Compositional matrix adjust.
Identities = 226/496 (46%), Positives = 326/496 (66%), Gaps = 18/496 (3%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D+LD G+L+ A V VL ++MA +D TVV+VA + F ++ + W TGYMLALATV
Sbjct 18 DKLDRGVLKVASVVVLGAIMAILDTTVVNVALQKLTIQFATSFDTIQWVATGYMLALATV 77
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IP GWA+DRFGT+RL++ ++ F +GS+L +A N+ LI FRVVQG GGGML P
Sbjct 78 IPVTGWASDRFGTKRLYLLAIGTFLVGSMLAGLAWNVESLIAFRVVQGLGGGMLMPAGMT 137
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
IL R AGP+R+GRVMAV+G+PMLLGP+ GPILGGWL+ + WRWIF +N+P+GL A VLA
Sbjct 138 ILTRAAGPQRIGRVMAVLGVPMLLGPICGPILGGWLVDSVSWRWIFYINVPIGLIAFVLA 197
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
+ P+D P FD++G+L++SPGLA +FGVS P+ GT+A V +PA+ GL L+
Sbjct 198 LRLLPKDEPEPGNRFDFLGMLMVSPGLAALIFGVSRIPSTGTVASLEVWLPALAGLVLLV 257
Query 275 AFVAHSWYRT-EHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPM 333
AFV + RT EHPLID++LF+NR+ + A +TM V +G FG+ LLLP+Y V ++ +
Sbjct 258 AFVLRA--RTMEHPLIDLKLFRNRSFSVAMITMAVFCVGFFGAMLLLPTYFVLVRGETAL 315
Query 334 QSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPI 393
+G+ + PQG GAMLAMPI G + D+ P +IV+ G++LIA G+ F V+ Y +
Sbjct 316 NAGLLLAPQGFGAMLAMPITGRLADKIAPRRIVVPGLVLIALGMVVFT-QVSATTPYWQL 374
Query 394 LPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTY 453
L T L +MG+GMGC+MMP++ AA+QTL +A+ ST ++ QQ G+IG+A+MS++L
Sbjct 375 L-TALFVMGIGMGCTMMPITSAALQTLRSKDMAKASTATNILQQTAGAIGSAVMSIIL-- 431
Query 454 QFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATA 513
+ ++A V + A ++P++ A + ++A F+ T
Sbjct 432 ----AALLAGKFGVPTSQGQLVATAATMNPATHDAAAGLAGE-------SFATTFLWGTI 480
Query 514 LVVSTLIPAAFLPKQQ 529
L+ L+PA FLPK++
Sbjct 481 LLAVCLVPALFLPKKR 496
>gi|119714403|ref|YP_921368.1| EmrB/QacA family drug resistance transporter [Nocardioides sp.
JS614]
gi|119535064|gb|ABL79681.1| drug resistance transporter, EmrB/QacA subfamily [Nocardioides
sp. JS614]
Length=504
Score = 420 bits (1080), Expect = 3e-115, Method: Compositional matrix adjust.
Identities = 255/524 (49%), Positives = 342/524 (66%), Gaps = 41/524 (7%)
Query 13 EGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVAD 72
E AP P GRP + P+ LD +L AGV VL ++M+ +D+TVVSVA +TF +
Sbjct 7 ERTAPAP----GRPVDAPDAPPEGLDRRVLMVAGVVVLGAIMSILDITVVSVALQTFQQE 62
Query 73 FGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNIL 132
F +T A VAWTMTGY LALA+VIP GWAADRFGT+RL++ +VL FT GS+LCA A ++
Sbjct 63 FDATSAEVAWTMTGYTLALASVIPLTGWAADRFGTKRLYLLAVLLFTAGSVLCAAATSLE 122
Query 133 LLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIG 192
+L+ FRV+QG GGGML P+ IL R AGP+R+GRVMAV+GIPMLLGP+ GPILGG LI
Sbjct 123 MLVSFRVLQGVGGGMLMPLGMTILTRAAGPERVGRVMAVLGIPMLLGPIFGPILGGALID 182
Query 193 AYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSP 252
+ W WIFL+NLP+G++AL AA+V PRD SE FD++G++LLSPGLA FL+GVSS P
Sbjct 183 SASWHWIFLINLPIGIAALAYAAVVLPRDHVEPSETFDWLGMVLLSPGLAAFLYGVSSIP 242
Query 253 A----RGTMADRHVLIPAITGLALIAAFVAHSWYRTE-HPLIDMRLFQNRAVAQANMTMT 307
A GT+ V+ PA+ GL LIAAFV + R HPL+D+RLF N + A ++M+
Sbjct 243 AAREEHGTLWTTEVVAPALAGLLLIAAFVPWALNRRNLHPLVDLRLFGNGTMTAAVLSMS 302
Query 308 VLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVL 367
+ ++ FG+ LL P Y Q V + + +G+ + PQG+GAM+ MPIAG + DR GP KIVL
Sbjct 303 LFAIAFFGASLLFPLYFQWVRGEDALGAGLLLAPQGVGAMITMPIAGVLADRIGPGKIVL 362
Query 368 VGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIAR 427
GI +I G+G F + + Y +L T L +MG+GMG +MMP+ AA+ TL H IAR
Sbjct 363 TGIAVITVGMGMFT-QLDQDTSYAYLL-TALFVMGLGMGATMMPIMSAALATLREHTIAR 420
Query 428 GSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLP 487
GSTL+++ QQV SIGTA+ ++LLT + L P AG
Sbjct 421 GSTLMNIVQQVAASIGTAVFAMLLTN-----------GTIDLDPSDPAG----------- 458
Query 488 RQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS 531
+ L+ A+A VFV+AT +V L+PA FLP+++ +
Sbjct 459 --------FVTGLADAFAHVFVVATVMVALVLVPAFFLPRRKVA 494
>gi|330467678|ref|YP_004405421.1| EmrB/QacA subfamily drug resistance transporter protein [Verrucosispora
maris AB-18-032]
gi|328810649|gb|AEB44821.1| drug resistance transporter, emrb/qaca subfamily protein [Verrucosispora
maris AB-18-032]
Length=533
Score = 416 bits (1069), Expect = 6e-114, Method: Compositional matrix adjust.
Identities = 256/511 (51%), Positives = 342/511 (67%), Gaps = 23/511 (4%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D+LD +L+ AGV VL ++M+ +DVTVV VA TF ++F ++ A VAWTMTGY LALATV
Sbjct 16 DKLDAAVLKVAGVVVLGAIMSILDVTVVGVALPTFQSEFDASYARVAWTMTGYTLALATV 75
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IP +GWAADRFGT+RL+M ++ FT+GS LCA A I LI +RV+QG GGGML P+
Sbjct 76 IPLSGWAADRFGTKRLYMMALALFTIGSGLCATADTIGQLIAYRVLQGLGGGMLMPLGMT 135
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
I+ R AGP R+GR+MAV+GIPMLLGP+GGPILGGWLI W WIFL+NLP+GL AL A
Sbjct 136 IMTRAAGPHRIGRLMAVLGIPMLLGPIGGPILGGWLIDVASWHWIFLINLPIGLVALAYA 195
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
P+D P SE+FD++G+L+LSPGLA FL+GVS+ P GT AD V +P + G AL+
Sbjct 196 QKALPKDNPEPSESFDFLGMLMLSPGLALFLYGVSTLPETGTFADTGVWLPMLIGAALVV 255
Query 275 AFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQ 334
AFV +S +R HPL+D+RLF+NR + A +TM V + G+ LL PSY QV +S +
Sbjct 256 AFVIYS-FRPRHPLLDLRLFRNRRLTVAAVTMFVFIIAFMGAGLLFPSYFLQVRGESTLA 314
Query 335 SGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPIL 394
+G+ I PQG+GAML MPIAG + D+ + V ++LI AG TF + Y+ I
Sbjct 315 AGLLIAPQGIGAMLTMPIAGMLADKVPVGRTVPFALLLIIAGFATFT-QIDANTSYVLIC 373
Query 395 PTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQ 454
+ L +MG+GMG +MMP+ +A++TL H++ARGSTL+++ QQ+GGSIG A+MSV+LT +
Sbjct 374 GS-LFVMGLGMGGTMMPIMTSALRTLTGHEVARGSTLVNILQQIGGSIGAAVMSVILTNE 432
Query 455 FNHSEIIATAKKVALTPESGAGRGAA------------VDPSSLPRQTNFAAQLLHDLSH 502
N+S I P + G A V+PS + R +FAA
Sbjct 433 LNNSRPIPGVTDPNGNPITETGLAIAAQQQPELLQQFPVEPSLIERGLDFAAD------- 485
Query 503 AYAVVFVIATALVVSTLIPAAFLP-KQQASH 532
A+A F +A LVV TLIPAAFLP +++ SH
Sbjct 486 AFATTFWVAFGLVVLTLIPAAFLPRRRERSH 516
>gi|326383993|ref|ZP_08205676.1| EmrB/QacA subfamily drug resistance transporter [Gordonia neofelifaecis
NRRL B-59395]
gi|326197153|gb|EGD54344.1| EmrB/QacA subfamily drug resistance transporter [Gordonia neofelifaecis
NRRL B-59395]
Length=518
Score = 415 bits (1067), Expect = 9e-114, Method: Compositional matrix adjust.
Identities = 233/498 (47%), Positives = 321/498 (65%), Gaps = 9/498 (1%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D+L + AGV VL ++M+ +DVTVV+VAQ TF+ +F ++ A AW+MTGY LALA V
Sbjct 11 DKLGRDVFIVAGVVVLGAIMSILDVTVVAVAQPTFMTEFDTSSASAAWSMTGYTLALAAV 70
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IPTA WAA RFGT+R++M S++ F +GS+LCA+A NI L+ FRV+QGFGGG+L P+
Sbjct 71 IPTASWAASRFGTKRVYMASLVLFLVGSVLCAMAWNIGSLVAFRVIQGFGGGLLMPIGMM 130
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
I+ R AGP+R+G VMAV+GIPMLLGP+ GPILGGWLI W W+FL+N+P+G+ ALV A
Sbjct 131 IMTRAAGPERVGSVMAVLGIPMLLGPIAGPILGGWLIEIASWHWVFLINVPIGVIALVYA 190
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
P + D GLL+LSPGLA FLFGVSSS T V IP I G LIA
Sbjct 191 FFALPGGDEEPGKKIDVPGLLMLSPGLALFLFGVSSSAEEQTFNAPRVYIPMIIGAVLIA 250
Query 275 AFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQ 334
F+ H+ +RT +PL+D+RLF+N + + +TM++ ++ FG+ LL P Y V +S +
Sbjct 251 GFIWHA-FRTTNPLLDLRLFRNSTLRVSVITMSLFAIAFFGASLLYPQYFIVVRGESTLM 309
Query 335 SGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPIL 394
+G+ + PQGLGAML MPIAG M D+ GP K VL G++LIA G+ F + Y L
Sbjct 310 AGLLLAPQGLGAMLTMPIAGKMTDKIGPGKFVLSGLVLIAIGVAAF-ITLGTDTSYW-FL 367
Query 395 PTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQ 454
L + G+GMG +MMP+ A++ TL +IA GSTL++ QQ SIGTA+++V+ T
Sbjct 368 CGALFVQGLGMGMTMMPIMSASLATLRGPEIADGSTLMNAIQQTSSSIGTAVITVIFTTM 427
Query 455 FN--HSEIIATAKKVALTPESGAGRGAAV-DPSSLPRQTNFAAQLLHDLSHAYAVVFVIA 511
I+ A T + G V DP+++ ++ D++ Y F++A
Sbjct 428 LMPLSRAIMQAGGDPAKTAGAMVENGVNVQDPAAVGAAGQ---SVISDIASTYGNTFIVA 484
Query 512 TALVVSTLIPAAFLPKQQ 529
TALVV TLIPA FLP+++
Sbjct 485 TALVVLTLIPAFFLPRKK 502
>gi|317124447|ref|YP_004098559.1| drug resistance transporter EmrB/QacA subfamily [Intrasporangium
calvum DSM 43043]
gi|315588535|gb|ADU47832.1| drug resistance transporter, EmrB/QacA subfamily [Intrasporangium
calvum DSM 43043]
Length=530
Score = 414 bits (1064), Expect = 2e-113, Method: Compositional matrix adjust.
Identities = 239/513 (47%), Positives = 332/513 (65%), Gaps = 29/513 (5%)
Query 32 SYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQA------VVAWTMT 85
++PD++D +L+ AGV VL S+M+ +D+TVV+VA TFV F + A VAWT+T
Sbjct 10 AHPDKIDAAVLKVAGVVVLGSIMSILDITVVNVALPTFVQAFSTNPADPLPYSTVAWTIT 69
Query 86 GYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGG 145
Y LALATVIP GWAADRFGTRRL+M ++ FTLGS LCA A +I +LI+FRV+QG GG
Sbjct 70 AYTLALATVIPLTGWAADRFGTRRLYMLALTLFTLGSALCATADSIGMLIVFRVLQGLGG 129
Query 146 GMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLP 205
G+L P+ IL + AGP+R+GR+MA++G+PMLLGP+ GPILGGWLI Y W WIFL+NLP
Sbjct 130 GLLMPLGMTILTKAAGPQRMGRLMAILGVPMLLGPIFGPILGGWLIDHYSWEWIFLINLP 189
Query 206 VGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIP 265
+G +A+ A P+DRP SE+FD +G+LL+SPGLA FL+GVSS P GT V +P
Sbjct 190 IGAAAVGYAWFALPKDRPEPSESFDVVGMLLMSPGLAAFLYGVSSIPGEGTFFSAKVGVP 249
Query 266 AITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQ 325
A G+ ++ AFV +S +R HPL+D+RLF NR + A +TM + + FG+ L+P+Y Q
Sbjct 250 ATVGVVMLVAFVLYS-FRPRHPLLDLRLFANRNLTVATVTMFLFAASFFGALFLVPTYFQ 308
Query 326 QVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFG-V 384
V + P+ SG + PQG+GAM+ MPIAGA+ DR +I G++LI G+ FA V
Sbjct 309 LVRGELPVDSGWLVAPQGVGAMVTMPIAGALADRFPVGRIAPFGLVLIVGGM--FALTQV 366
Query 385 ARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGT 444
Y L L +MG+GMG +MMP+ +A++TL HQ+ARGSTL+++ QQV SIG
Sbjct 367 TADTSYWGYLIPVLFVMGLGMGATMMPIMTSALKTLTSHQVARGSTLLNITQQVASSIGI 426
Query 445 ALMSVLLTYQFNHSEI----IATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDL 500
A++SV+ T + IA+ + ++ + G G AQ L
Sbjct 427 AVISVVYTNMLAQKPLAGPAIASWRNPSIADQIGGPAG--------------VAQGLGQA 472
Query 501 SHAYAVVFVIATALVVSTLIPAAFLP-KQQASH 532
+ A+ F++A LV TL+PA LP +++ SH
Sbjct 473 ADAFGDTFLVAAVLVTLTLVPALLLPRRREPSH 505
>gi|226361044|ref|YP_002778822.1| drug resistance efflux protein [Rhodococcus opacus B4]
gi|226239529|dbj|BAH49877.1| drug resistance efflux protein [Rhodococcus opacus B4]
Length=509
Score = 413 bits (1061), Expect = 4e-113, Method: Compositional matrix adjust.
Identities = 250/499 (51%), Positives = 339/499 (68%), Gaps = 14/499 (2%)
Query 34 PDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALAT 93
PD+LD +L+ A V VL ++M+ +DVTVVSVA TF +F +T A VAWTMT Y LALAT
Sbjct 11 PDKLDGTVLKIASVVVLGAIMSILDVTVVSVALPTFATEFDTTYATVAWTMTAYTLALAT 70
Query 94 VIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSF 153
VIP GWAADRFGT+RL+M +++ F LGS+LC+ A +I LI FRV+QG GGGML P+
Sbjct 71 VIPVTGWAADRFGTKRLYMTALVLFVLGSVLCSFAWDITSLIGFRVLQGLGGGMLMPLGM 130
Query 154 AILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVL 213
I+ + AGP R+GRVMAV+GIPMLLGP+GGPILGGWLI A W WIFL+NLP+G+ AL
Sbjct 131 TIMTKAAGPDRVGRVMAVLGIPMLLGPIGGPILGGWLIEAASWHWIFLINLPIGVIALAA 190
Query 214 AAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALI 273
A ++ P D + SE+FD++G+LLLSPGLA FLFGVSS P GT+A VL+P + GL LI
Sbjct 191 AFVILPSDNASPSESFDFLGMLLLSPGLALFLFGVSSIPEVGTVASARVLVPGVIGLVLI 250
Query 274 AAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPM 333
AF+ H+ R +HPLID+ LF+NR ++ A +T ++ + G+ LL PSY QV + +
Sbjct 251 VAFIFHA-LRKDHPLIDLHLFKNRQLSVAVITTSLFIVAFMGAGLLFPSYFIQVGGHTTL 309
Query 334 QSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPI 393
+G+ + PQG+GAML MP+AG ++D+ GP KIVL G+ LI G+G F + +L
Sbjct 310 AAGLLMAPQGIGAMLTMPVAGRLVDKMGPGKIVLTGLPLILIGIGVFTQVASDSPTWL-- 367
Query 394 LPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTY 453
L L +MGMGMGC+MMPL AA+ TL+ Q+ARGSTL+++ QQ GSIGTA+MSV+LT
Sbjct 368 LMGALFVMGMGMGCTMMPLMTAAIVTLSNDQVARGSTLMNIVQQTAGSIGTAVMSVVLTN 427
Query 454 QFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATA 513
Q + + + PE AA +P + Q+L + A+ F++A
Sbjct 428 QLLDRGLDSQTVAMQHVPEV-----AAQEPPGM------VDQVLSQAADAFGNTFLVAAV 476
Query 514 LVVSTLIPAAFLPKQQASH 532
L+ T IPA LP++++ +
Sbjct 477 LIALTFIPAFLLPRKKSVN 495
>gi|111018946|ref|YP_701918.1| major facilitator superfamily multidrug resistance protein [Rhodococcus
jostii RHA1]
gi|110818476|gb|ABG93760.1| multidrug resistance transporter, MFS superfamily protein [Rhodococcus
jostii RHA1]
Length=509
Score = 412 bits (1060), Expect = 6e-113, Method: Compositional matrix adjust.
Identities = 256/507 (51%), Positives = 344/507 (68%), Gaps = 14/507 (2%)
Query 28 SGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGY 87
+ + PD+LD +L+ A V VL ++M+ +DVTVVSVA TF +F +T A VAWTMT Y
Sbjct 5 TAANAAPDKLDGTVLKIASVVVLGAIMSILDVTVVSVALPTFATEFDTTYATVAWTMTAY 64
Query 88 MLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGM 147
LALATVIP GWAADRFGT+RL+M +++ F LGS+LC+ A +I LI FRV+QG GGGM
Sbjct 65 TLALATVIPVTGWAADRFGTKRLYMTALVLFVLGSVLCSFAWDITSLIGFRVLQGLGGGM 124
Query 148 LTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVG 207
L P+ I+ + AGP R+GRVMAV+GIPMLLGP+GGPILGGWLI A W WIFL+NLP+G
Sbjct 125 LMPLGMTIMTKAAGPDRVGRVMAVLGIPMLLGPIGGPILGGWLIEAASWHWIFLINLPIG 184
Query 208 LSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAI 267
+ AL A I+ P D + SE+FD++G+LLLSPGLA FLFGVSS P GT+A VL+P
Sbjct 185 IIALAAAFIILPSDNASPSESFDFLGMLLLSPGLALFLFGVSSIPEVGTVASARVLVPGA 244
Query 268 TGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQV 327
GLALI AFV H+ R +HPLID+ LF+NR ++ A +T ++ + G+ LL PSY QV
Sbjct 245 IGLALIVAFVVHA-LRKDHPLIDLHLFKNRQLSVAVITTSLFIVAFMGAGLLFPSYFIQV 303
Query 328 LHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQ 387
+ + +G+ + PQG+GAML MP+AG ++D+ GP KIVL G+ LI GLG F +
Sbjct 304 GGHTTLAAGLLMAPQGIGAMLTMPVAGRLVDKIGPGKIVLTGLPLILIGLGVFTQVASDS 363
Query 388 ADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALM 447
+L L L +MGMGMGC+MMPL AA+ TL+ Q+ARGSTL+++ QQ GSIGTA+M
Sbjct 364 PTWL--LMGALFVMGMGMGCTMMPLMTAAIVTLSNEQVARGSTLMNIVQQTAGSIGTAVM 421
Query 448 SVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVV 507
SV+LT Q + + + PE AA +P + Q+L + A+
Sbjct 422 SVVLTNQLLDRGLDSQTVAMQHVPEV-----AAQEPPGM------VDQVLSQAADAFGNT 470
Query 508 FVIATALVVSTLIPAAFLPKQQASHRR 534
F++AT L+ TLIPA LP++++ + +
Sbjct 471 FLVATVLIALTLIPAFLLPRKKSVNPK 497
>gi|145593638|ref|YP_001157935.1| EmrB/QacA family drug resistance transporter [Salinispora tropica
CNB-440]
gi|145302975|gb|ABP53557.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora
tropica CNB-440]
Length=531
Score = 407 bits (1047), Expect = 2e-111, Method: Compositional matrix adjust.
Identities = 251/513 (49%), Positives = 344/513 (68%), Gaps = 22/513 (4%)
Query 34 PDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALAT 93
PD+LD +L+ AGV VL ++M+ +DVTVVSVA TF +F ++ A VAWTMTGY LALAT
Sbjct 15 PDKLDAAVLKVAGVVVLGAIMSILDVTVVSVALPTFQNEFDASYARVAWTMTGYTLALAT 74
Query 94 VIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSF 153
VIP +GWAADRFGT+RL+M ++ FT+GS LCA A +I LI +RV+QG GGGML P+
Sbjct 75 VIPLSGWAADRFGTKRLYMIALALFTIGSGLCATADSIGELIAYRVLQGLGGGMLMPIGM 134
Query 154 AILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVL 213
I+ R AGP R+GR+MAV+GIPMLLGP+GGPILGGWLI W WIFL+NLP+GL ALV
Sbjct 135 TIMTRAAGPHRIGRLMAVLGIPMLLGPIGGPILGGWLIDVASWHWIFLINLPIGLLALVY 194
Query 214 AAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALI 273
A + P+D P SE+FD +G+L+LSPGLA FL+GVS+ P GT D V +P + G+AL+
Sbjct 195 AQLALPKDAPEPSESFDVLGMLMLSPGLALFLYGVSTLPEAGTFTDPEVWVPMLLGVALV 254
Query 274 AAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPM 333
+FV +S ++ +HPL+D+RLF+NR + A++T+ V + G+ LL PSY QV +S +
Sbjct 255 VSFVRYS-FKPQHPLLDLRLFRNRRLTIASVTLFVFIVAFMGAGLLFPSYFLQVRGESTL 313
Query 334 QSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPI 393
+G+ I PQG+GAM+ MPIAG + DR + V ++LIAAG TF V YL +
Sbjct 314 HAGLLIAPQGIGAMVTMPIAGTLADRVPVGRTVPFALVLIAAGFFTFT-QVGPDTSYL-L 371
Query 394 LPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTY 453
+ L +MG+GMG +MMP+ +A++TL ++ARGSTL+++ QQ+GGS+G A+MSV+LT
Sbjct 372 ICGSLFVMGLGMGGTMMPIMTSALRTLTGPEVARGSTLMNIIQQIGGSVGAAVMSVILTN 431
Query 454 QFNHSEIIATAKKVALTPESGAGRGAAV-----------DPSSLPRQTNFAAQLLHDLSH 502
+ N S I P + AG A DP+ + R FAA
Sbjct 432 ELNGSRPIPGLTGSNGEPVTEAGLAIAAQRQPELAQQVPDPTLIERGLAFAAD------- 484
Query 503 AYAVVFVIATALVVSTLIPAAFLPKQ-QASHRR 534
++A F +A ALV+ T +P AFLP++ + S R
Sbjct 485 SFAATFWVAFALVLLTFVPVAFLPRRWERSQSR 517
>gi|159036624|ref|YP_001535877.1| EmrB/QacA family drug resistance transporter [Salinispora arenicola
CNS-205]
gi|157915459|gb|ABV96886.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora
arenicola CNS-205]
Length=534
Score = 407 bits (1045), Expect = 3e-111, Method: Compositional matrix adjust.
Identities = 248/504 (50%), Positives = 338/504 (68%), Gaps = 21/504 (4%)
Query 35 DRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATV 94
D+LD +L+ AGV VL ++M+ +DVTVVSVA TF +F ++ A VAWTMTGY LALATV
Sbjct 15 DKLDAAVLKVAGVVVLGAIMSILDVTVVSVALPTFQNEFDASYARVAWTMTGYTLALATV 74
Query 95 IPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFA 154
IP +GWAA+RFGT+RL+M ++ FT+GS LCA A I LI +RV+QG GGGML P+
Sbjct 75 IPLSGWAANRFGTKRLYMVALALFTIGSGLCATADTIGQLIAYRVLQGLGGGMLMPIGMT 134
Query 155 ILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLA 214
I+ R AGP R+GR+MAV+GIPMLLGP+GGPILGGWLI W WIFL+NLP+GL AL A
Sbjct 135 IMTRAAGPHRIGRLMAVLGIPMLLGPIGGPILGGWLIDVASWHWIFLINLPIGLIALAYA 194
Query 215 AIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIA 274
P+D P SE+FD+ G+L+LSPGLA FL+GVS+ P GT D V +P + G AL+
Sbjct 195 QAALPKDTPEPSESFDFFGMLMLSPGLALFLYGVSTLPEAGTFTDPEVWVPMLLGAALVV 254
Query 275 AFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQ 334
+FV +S ++ +HPL+D+RLF+NR +A A++ M V + G+ LL PSY QV +S +
Sbjct 255 SFVRYS-FKPQHPLLDLRLFRNRRLAVASVAMFVFIVAFMGAGLLFPSYFLQVRGESTLH 313
Query 335 SGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPIL 394
+G+ I PQG+GAM+ MPIAG + DR + V ++L+AAG TF V YL I
Sbjct 314 AGLLIAPQGIGAMVTMPIAGTLADRVSVGRTVPFALVLLAAGFLTFT-QVGPDTSYLLIC 372
Query 395 PTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQ 454
+ L +MG+GMG +MMP+ +A++TL H++ARGSTL+++ QQ+GGS+G A+MSV+LT +
Sbjct 373 GS-LFVMGLGMGGTMMPIMTSALRTLTGHEVARGSTLLNIIQQIGGSVGAAVMSVILTNE 431
Query 455 FNHSEIIATAKKVALTPESGAGRGAAV-----------DPSSLPRQTNFAAQLLHDLSHA 503
N S I + P + AG A DP+ + R +FAA+ +
Sbjct 432 LNGSRPIPGLTDPSGEPITEAGLAIAAQRQPELAQQVSDPTLIERGLDFAAE-------S 484
Query 504 YAVVFVIATALVVSTLIPAAFLPK 527
+A F +A LV+ T IP AFLP+
Sbjct 485 FASTFWVAFVLVLLTFIPVAFLPR 508
>gi|84497916|ref|ZP_00996713.1| putative transporter [Janibacter sp. HTCC2649]
gi|84381416|gb|EAP97299.1| putative transporter [Janibacter sp. HTCC2649]
Length=543
Score = 404 bits (1039), Expect = 2e-110, Method: Compositional matrix adjust.
Identities = 243/531 (46%), Positives = 336/531 (64%), Gaps = 38/531 (7%)
Query 30 QRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQ-----AVVAWTM 84
Q YP+++D +L+ AGV VL ++M+ +D+TVV+VA F T + VAWT+
Sbjct 6 QIEYPEKIDGAVLKIAGVVVLGAIMSILDITVVNVALPDLQVTFTGTDNPLPYSTVAWTV 65
Query 85 TGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFG 144
T Y LALATVIP GWAADRFGT+RL+M ++ FTLGS LCA A +I +LI+FRV+QG G
Sbjct 66 TAYTLALATVIPLTGWAADRFGTKRLYMAALTLFTLGSALCAAATSINMLILFRVIQGLG 125
Query 145 GGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNL 204
GG+L P+ I+ + AGP R+GR+MA++G+PMLLGP+ GPILGG+LI W WIFL+NL
Sbjct 126 GGLLMPLGMVIMTKAAGPARMGRLMAILGVPMLLGPIAGPILGGFLIVNLSWHWIFLINL 185
Query 205 PVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLI 264
P+GL AL A +D P +E+FD++G+LL+SPGLA FL+G+SS P GT VL
Sbjct 186 PLGLLALGYAWWALAKDAPEPTESFDFVGMLLMSPGLAFFLYGISSIPEAGTFFSARVLG 245
Query 265 PAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYL 324
A GLALI AFV +S ++ EHPL+D+RLF+NR + + +TM + + FG LL+P+YL
Sbjct 246 FAGAGLALIVAFVFYS-FKPEHPLLDLRLFKNRNLTWSIITMFIFAGAFFGGLLLVPTYL 304
Query 325 QQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFG- 383
QQV +S + +G I PQGLGAML MPIAG + D+ +IV VG++LI G+ FA
Sbjct 305 QQVRGESALSAGWLIAPQGLGAMLTMPIAGVLADKFPVGRIVPVGLVLITGGM--FALTQ 362
Query 384 VARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIG 443
V Y L L +MG+GMG +MMPL +A++TL HQ+ARGSTL++++QQV SIG
Sbjct 363 VDGDTSYWGYLIPVLFVMGLGMGATMMPLMTSALKTLTAHQVARGSTLLNISQQVASSIG 422
Query 444 TALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSS---LPRQTNFAAQLL--- 497
A++SV+LT + +++ A A E+ G VDPS L + Q+L
Sbjct 423 VAIISVVLTNGLKNDPLVSQAGAFA---EASKG----VDPSQTGGLLEKFPLVGQILGQF 475
Query 498 ---------------HDLSHAYAVVFVIATALVVSTLIPAAFLP-KQQASH 532
+ + + F +A +V TL+ A FLP K + SH
Sbjct 476 QDPAAGAAALKSAVENSMGEVFGNTFFVAAIMVAFTLVSAWFLPRKHEESH 526
>gi|118616372|ref|YP_904704.1| multidrug resistance integral membrane efflux protein [Mycobacterium
ulcerans Agy99]
gi|118568482|gb|ABL03233.1| multidrug resistance integral membrane efflux protein [Mycobacterium
ulcerans Agy99]
Length=417
Score = 397 bits (1019), Expect = 3e-108, Method: Compositional matrix adjust.
Identities = 211/403 (53%), Positives = 279/403 (70%), Gaps = 0/403 (0%)
Query 44 TAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAAD 103
T C++ VM +D TVV+VAQRTF+ +F STQAVVAWT TGY L+LA+VIP GW A+
Sbjct 2 TTATCLMLPVMVTLDTTVVNVAQRTFIEEFSSTQAVVAWTSTGYTLSLASVIPLTGWTAN 61
Query 104 RFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPK 163
R GT+RL MGSVL FTLGSLLCA+A +I LL+ FR QG GGG+L P+ ILAR AGP
Sbjct 62 RLGTKRLVMGSVLLFTLGSLLCAMASSITLLVAFRAAQGLGGGILIPLQLIILARAAGPA 121
Query 164 RLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRP 223
RLGRV+ + I +L+ P+ GPILGGWLI A+GW+WIFL+NLP+G L+LA +V P D
Sbjct 122 RLGRVLTISMISVLMAPIAGPILGGWLIDAFGWQWIFLINLPIGALTLILAGLVLPGDDS 181
Query 224 AASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYR 283
+E+ D +G+ LLSP L L+G+S+ PARGT+ D V +P GL LI F H+ +R
Sbjct 182 LPAESLDLVGMALLSPALVLLLYGLSALPARGTIGDPQVWLPTTVGLILIGGFALHALHR 241
Query 284 TEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQG 343
+H LID+RL +NRAVA AN T + ++ FGS LL P+Y QQVL ++P+QSG+ +IPQ
Sbjct 242 GDHALIDLRLLKNRAVAAANATRFMFAVTFFGSCLLFPAYFQQVLGKTPLQSGLLLIPQT 301
Query 344 LGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGM 403
L A MPI G +M++RGP +VL+G L G+G F +G++R+ +LP L GL G+
Sbjct 302 LAAAAVMPIVGRLMEKRGPRDVVLMGTALTVVGMGIFIYGMSREHVHLPALLIGLGTFGV 361
Query 404 GMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTAL 446
G M+P+S +AV L ++A GSTL +VN V S+G AL
Sbjct 362 GTAAMMVPVSWSAVHMLNSSEVAHGSTLFNVNHNVAASVGAAL 404
Lambda K H
0.326 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 1189573419810
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40