BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0809

Length=364
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607949|ref|NP_215324.1|  phosphoribosylaminoimidazole synthe...   728    0.0   
gi|340625824|ref|YP_004744276.1|  putative phosphoribosylformylgl...   726    0.0   
gi|289446373|ref|ZP_06436117.1|  phosphoribosylformylglycinamidin...   725    0.0   
gi|296166434|ref|ZP_06848866.1|  phosphoribosylformylglycinamidin...   645    0.0   
gi|41406737|ref|NP_959573.1|  phosphoribosylaminoimidazole synthe...   636    2e-180
gi|254773689|ref|ZP_05215205.1|  phosphoribosylaminoimidazole syn...   636    2e-180
gi|336458324|gb|EGO37303.1|  phosphoribosylaminoimidazole synthet...   635    4e-180
gi|342860282|ref|ZP_08716933.1|  phosphoribosylaminoimidazole syn...   634    6e-180
gi|254821044|ref|ZP_05226045.1|  phosphoribosylaminoimidazole syn...   633    1e-179
gi|118616271|ref|YP_904603.1|  phosphoribosylaminoimidazole synth...   633    2e-179
gi|183984848|ref|YP_001853139.1|  5'-phosphoribosyl-5-aminoimidaz...   630    8e-179
gi|145222228|ref|YP_001132906.1|  phosphoribosylaminoimidazole sy...   624    9e-177
gi|315442668|ref|YP_004075547.1|  phosphoribosylformylglycinamidi...   623    1e-176
gi|15828183|ref|NP_302446.1|  phosphoribosylaminoimidazole synthe...   610    8e-173
gi|118467597|ref|YP_890026.1|  phosphoribosylaminoimidazole synth...   608    3e-172
gi|108801501|ref|YP_641698.1|  phosphoribosylaminoimidazole synth...   606    2e-171
gi|333992191|ref|YP_004524805.1|  5'-phosphoribosyl-5-aminoimidaz...   600    1e-169
gi|120406059|ref|YP_955888.1|  phosphoribosylaminoimidazole synth...   597    9e-169
gi|240172678|ref|ZP_04751337.1|  phosphoribosylaminoimidazole syn...   590    2e-166
gi|169627829|ref|YP_001701478.1|  phosphoribosylaminoimidazole sy...   572    3e-161
gi|54022547|ref|YP_116789.1|  phosphoribosylaminoimidazole synthe...   559    2e-157
gi|312138305|ref|YP_004005641.1|  phosphoribosylformylglycinamidi...   556    2e-156
gi|226308311|ref|YP_002768271.1|  aminoimidazole ribonucleotide s...   552    3e-155
gi|111021812|ref|YP_704784.1|  phosphoribosylaminoimidazole synth...   549    3e-154
gi|326384542|ref|ZP_08206221.1|  phosphoribosylaminoimidazole syn...   530    2e-148
gi|333918373|ref|YP_004491954.1|  phosphoribosylformylglycinamidi...   527    1e-147
gi|291008351|ref|ZP_06566324.1|  phosphoribosylaminoimidazole syn...   526    2e-147
gi|134103546|ref|YP_001109207.1|  phosphoribosylaminoimidazole sy...   523    2e-146
gi|256380840|ref|YP_003104500.1|  phosphoribosylaminoimidazole sy...   522    4e-146
gi|344046352|gb|EGV42018.1|  phosphoribosylaminoimidazole synthet...   519    3e-145
gi|145296578|ref|YP_001139399.1|  phosphoribosylaminoimidazole sy...   519    4e-145
gi|19553779|ref|NP_601781.1|  phosphoribosylaminoimidazole synthe...   518    6e-145
gi|262200945|ref|YP_003272153.1|  phosphoribosylformylglycinamidi...   517    1e-144
gi|343925899|ref|ZP_08765414.1|  aminoimidazole ribonucleotide sy...   515    4e-144
gi|302531031|ref|ZP_07283373.1|  phosphoribosylformylglycinamidin...   515    4e-144
gi|25029031|ref|NP_739085.1|  phosphoribosylaminoimidazole synthe...   509    4e-142
gi|300790834|ref|YP_003771125.1|  phosphoribosylformylglycinamidi...   509    4e-142
gi|325001983|ref|ZP_08123095.1|  phosphoribosylaminoimidazole syn...   506    2e-141
gi|331694324|ref|YP_004330563.1|  phosphoribosylformylglycinamidi...   505    4e-141
gi|296141249|ref|YP_003648492.1|  phosphoribosylformylglycinamidi...   498    5e-139
gi|227547968|ref|ZP_03978017.1|  phosphoribosylformylglycinamidin...   489    3e-136
gi|311740214|ref|ZP_07714046.1|  phosphoribosylaminoimidazole syn...   489    3e-136
gi|255325913|ref|ZP_05367005.1|  phosphoribosylformylglycinamidin...   487    1e-135
gi|38234486|ref|NP_940253.1|  phosphoribosylaminoimidazole synthe...   486    2e-135
gi|334697525|gb|AEG82322.1|  phosphoribosylformylglycinamidine cy...   485    4e-135
gi|227506373|ref|ZP_03936422.1|  phosphoribosylformylglycinamidin...   484    9e-135
gi|296395398|ref|YP_003660282.1|  phosphoribosylformylglycinamidi...   483    2e-134
gi|337291500|ref|YP_004630521.1|  phosphoribosylformylglycinamidi...   483    2e-134
gi|300859138|ref|YP_003784121.1|  phosphoribosylformylglycinamidi...   482    4e-134
gi|257057726|ref|YP_003135558.1|  phosphoribosylformylglycinamidi...   478    5e-133


>gi|15607949|ref|NP_215324.1| phosphoribosylaminoimidazole synthetase [Mycobacterium tuberculosis 
H37Rv]
 gi|15840221|ref|NP_335258.1| phosphoribosylaminoimidazole synthetase [Mycobacterium tuberculosis 
CDC1551]
 gi|31791997|ref|NP_854490.1| phosphoribosylaminoimidazole synthetase [Mycobacterium bovis 
AF2122/97]
 76 more sequence titles
 Length=364

 Score =  728 bits (1879),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 364/364 (100%), Positives = 364/364 (100%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT
Sbjct  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA
Sbjct  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL
Sbjct  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR
Sbjct  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ
Sbjct  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|340625824|ref|YP_004744276.1| putative phosphoribosylformylglycinamidine cyclo-ligase PURM 
[Mycobacterium canettii CIPT 140010059]
 gi|340004014|emb|CCC43150.1| putative phosphoribosylformylglycinamidine cyclo-ligase PURM 
(AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase) 
[Mycobacterium canettii CIPT 140010059]
Length=364

 Score =  726 bits (1874),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/364 (99%), Positives = 364/364 (100%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT
Sbjct  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA
Sbjct  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL
Sbjct  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAG+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR
Sbjct  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ
Sbjct  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|289446373|ref|ZP_06436117.1| phosphoribosylformylglycinamidine cyclo-ligase purM [Mycobacterium 
tuberculosis CPHL_A]
 gi|289419331|gb|EFD16532.1| phosphoribosylformylglycinamidine cyclo-ligase purM [Mycobacterium 
tuberculosis CPHL_A]
Length=364

 Score =  725 bits (1872),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/364 (99%), Positives = 363/364 (99%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT
Sbjct  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA
Sbjct  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL
Sbjct  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEI RMNLAGHVEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIHRMNLAGHVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR
Sbjct  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ
Sbjct  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|296166434|ref|ZP_06848866.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295898195|gb|EFG77769.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=389

 Score =  645 bits (1663),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 327/364 (90%), Positives = 347/364 (96%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K PG++PGS GITYASAGVDIEAGDRA+++FKPLA++ATRPEVRGGLGGFAGLF 
Sbjct  26   MTDPGKSPGRNPGSHGITYASAGVDIEAGDRAVEMFKPLATRATRPEVRGGLGGFAGLFA  85

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LR DYREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  86   LRNDYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  145

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIVAGIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VL
Sbjct  146  VGRTVPERLSAIVAGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVL  205

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGD IIAMGSSGLHSNGYSL R VLLEIDRMNLAG+VEEFGRTLGEELLEPTRI
Sbjct  206  GPDRVKPGDTIIAMGSSGLHSNGYSLARTVLLEIDRMNLAGYVEEFGRTLGEELLEPTRI  265

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLAL AET VRTFCHVTGGGLAGNLQRVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  266  YAKDCLALTAETHVRTFCHVTGGGLAGNLQRVIPHGLVAEIDRGTWTPAPVFAMIAQRGR  325

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGM+AVVAPEDT RALA+LTARHLDCWVLGTVCKGGK+GPRAKLVGQ
Sbjct  326  VTRDEMEKTFNMGVGMVAVVAPEDTDRALAILTARHLDCWVLGTVCKGGKEGPRAKLVGQ  385

Query  361  HPRF  364
            HPRF
Sbjct  386  HPRF  389


>gi|41406737|ref|NP_959573.1| phosphoribosylaminoimidazole synthetase [Mycobacterium avium 
subsp. paratuberculosis K-10]
 gi|118464238|ref|YP_880023.1| phosphoribosylaminoimidazole synthetase [Mycobacterium avium 
104]
 gi|41395087|gb|AAS02956.1| PurM [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118165525|gb|ABK66422.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
avium 104]
Length=364

 Score =  636 bits (1641),  Expect = 2e-180, Method: Compositional matrix adjust.
 Identities = 327/364 (90%), Positives = 345/364 (95%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K PG+  GS+GITYASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF 
Sbjct  1    MTDPGKSPGRHSGSQGITYASAGVDIEAGDRAVELFKPLATKATRPEVRGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRG+YREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRGEYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV+GIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VL
Sbjct  121  VGRTVPERLSAIVSGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNL G+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLARTVLLEIDRMNLEGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAET VRTFCHVTGGGLAGNL RVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALAAETHVRTFCHVTGGGLAGNLARVIPHGLVAELDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTV KGGK GPRAKLVGQ
Sbjct  301  VTREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVGKGGKAGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|254773689|ref|ZP_05215205.1| phosphoribosylaminoimidazole synthetase [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=364

 Score =  636 bits (1640),  Expect = 2e-180, Method: Compositional matrix adjust.
 Identities = 327/364 (90%), Positives = 345/364 (95%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K PG+  GS+GITYASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF 
Sbjct  1    MTDPGKSPGRHSGSQGITYASAGVDIEAGDRAVELFKPLATKATRPEVRGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRG+YREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRGEYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV+GIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VL
Sbjct  121  VGRTVPERLSAIVSGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNL G+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLARAVLLEIDRMNLEGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAET VRTFCHVTGGGLAGNL RVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALAAETHVRTFCHVTGGGLAGNLARVIPHGLVAELDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTV KGGK GPRAKLVGQ
Sbjct  301  VTREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVGKGGKAGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|336458324|gb|EGO37303.1| phosphoribosylaminoimidazole synthetase [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=364

 Score =  635 bits (1638),  Expect = 4e-180, Method: Compositional matrix adjust.
 Identities = 326/364 (90%), Positives = 345/364 (95%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K PG+  GS+GITYASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF 
Sbjct  1    MTDPGKSPGRHSGSQGITYASAGVDIEAGDRAVELFKPLATKATRPEVRGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRG+YREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRGEYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV+GIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VL
Sbjct  121  VGRTVPERLSAIVSGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNL G+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLARTVLLEIDRMNLEGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAET VRTFCHVTGGGLAGNL RVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALAAETHVRTFCHVTGGGLAGNLARVIPHGLVAELDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EME+TFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTV KGGK GPRAKLVGQ
Sbjct  301  VTREEMEQTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVGKGGKAGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|342860282|ref|ZP_08716933.1| phosphoribosylaminoimidazole synthetase [Mycobacterium colombiense 
CECT 3035]
 gi|342131937|gb|EGT85178.1| phosphoribosylaminoimidazole synthetase [Mycobacterium colombiense 
CECT 3035]
Length=364

 Score =  634 bits (1635),  Expect = 6e-180, Method: Compositional matrix adjust.
 Identities = 324/364 (90%), Positives = 345/364 (95%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K PG+  GS+GITYASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF 
Sbjct  1    MTDPGKSPGRHHGSQGITYASAGVDIEAGDRAVELFKPLATKATRPEVRGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRGDYREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRGDYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV+GIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATG+GVVEAD+VL
Sbjct  121  VGRTVPERLSAIVSGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGIGVVEADDVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNL G+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLARTVLLEIDRMNLEGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLAL AET VRTFCHVTGGGLAGNL RVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALCAETHVRTFCHVTGGGLAGNLARVIPHGLVAEMDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGMIA+VAPEDT RALA+LTARHLDCWVLGTV KGGK+GPRAK+VGQ
Sbjct  301  VTREEMEKTFNMGVGMIAIVAPEDTDRALAILTARHLDCWVLGTVGKGGKEGPRAKMVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|254821044|ref|ZP_05226045.1| phosphoribosylaminoimidazole synthetase [Mycobacterium intracellulare 
ATCC 13950]
Length=364

 Score =  633 bits (1633),  Expect = 1e-179, Method: Compositional matrix adjust.
 Identities = 325/364 (90%), Positives = 343/364 (95%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD  K P +  GS+GITYASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF 
Sbjct  1    MTDPGKSPARHAGSQGITYASAGVDIEAGDRAVELFKPLATKATRPEVRGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LRGDYREP+LAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRGDYREPLLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV+GIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATG+GVVEAD+VL
Sbjct  121  VGRTVPERLSAIVSGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGIGVVEADDVL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNL G+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIAMGSSGLHSNGYSLARTVLLEIDRMNLEGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLAL AET VRTFCHVTGGGLAGNL RVIPHGL+AE+DRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALCAETHVRTFCHVTGGGLAGNLARVIPHGLVAEMDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTV KGGK GPRAKLVGQ
Sbjct  301  VTREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVGKGGKAGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|118616271|ref|YP_904603.1| phosphoribosylaminoimidazole synthetase [Mycobacterium ulcerans 
Agy99]
 gi|118568381|gb|ABL03132.1| 5'-phosphoribosyl-5-aminoimidazole synthetase, PurM [Mycobacterium 
ulcerans Agy99]
Length=387

 Score =  633 bits (1632),  Expect = 2e-179, Method: Compositional matrix adjust.
 Identities = 323/367 (89%), Positives = 345/367 (95%), Gaps = 3/367 (0%)

Query  1    MTDLAKGP---GKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAG  57
            MTD  K P   G+ P S+G+TYA+AGVDIEAGDRA++LFKPLA++ATRPEVRGGLGGFAG
Sbjct  21   MTDPEKSPESSGRGPASQGVTYAAAGVDIEAGDRAVELFKPLATRATRPEVRGGLGGFAG  80

Query  58   LFTLRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLD  117
            LF LR DYREPVLAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL D
Sbjct  81   LFALRNDYREPVLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQD  140

Query  118  YIAVGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEAD  177
            YIAVGR VPER+SAIV+GIA+GC+RAGCALLGGETAEHPGL+ PDHYDISATGVGVVEAD
Sbjct  141  YIAVGRTVPERVSAIVSGIAEGCVRAGCALLGGETAEHPGLMAPDHYDISATGVGVVEAD  200

Query  178  NVLGPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEP  237
            NVLGP+RVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNLAG+VEEFGRTLGEELLEP
Sbjct  201  NVLGPERVKPGDVIIAMGSSGLHSNGYSLARNVLLEIDRMNLAGYVEEFGRTLGEELLEP  260

Query  238  TRIYAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQ  297
            TRIYAKDCLAL AET VRTFCHVTGGGLAGNL+RVIPHGL+AE+DRGTWTPAPVF MIAQ
Sbjct  261  TRIYAKDCLALTAETHVRTFCHVTGGGLAGNLERVIPHGLVAEIDRGTWTPAPVFAMIAQ  320

Query  298  RGRVRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKL  357
            RGRV R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTVCKGGK+GPRA L
Sbjct  321  RGRVVREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVCKGGKEGPRATL  380

Query  358  VGQHPRF  364
            VGQHPRF
Sbjct  381  VGQHPRF  387


>gi|183984848|ref|YP_001853139.1| 5'-phosphoribosyl-5-aminoimidazole synthetase, PurM [Mycobacterium 
marinum M]
 gi|183178174|gb|ACC43284.1| 5'-phosphoribosyl-5-aminoimidazole synthetase, PurM [Mycobacterium 
marinum M]
Length=367

 Score =  630 bits (1626),  Expect = 8e-179, Method: Compositional matrix adjust.
 Identities = 322/367 (88%), Positives = 345/367 (95%), Gaps = 3/367 (0%)

Query  1    MTDLAKGP---GKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAG  57
            MTD  K P   G+ P S+G+TYA+AGVDIEAGDRA++LFKPLA++ATRPEVRGGLGGFAG
Sbjct  1    MTDPEKSPESSGRGPASQGVTYAAAGVDIEAGDRAVELFKPLATRATRPEVRGGLGGFAG  60

Query  58   LFTLRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLD  117
            LF LR DYREPVLAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL D
Sbjct  61   LFALRNDYREPVLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQD  120

Query  118  YIAVGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEAD  177
            YIAVGR VPER+SAIV+GIA+GC+RAGCALLGGETAEHPGL+ PDHYDISATGVGVVEAD
Sbjct  121  YIAVGRTVPERVSAIVSGIAEGCVRAGCALLGGETAEHPGLMAPDHYDISATGVGVVEAD  180

Query  178  NVLGPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEP  237
            +VLGP+RVKPGDVIIAMGSSGLHSNGYSL R VLLEIDRMNLAG+VEEFGRTLGEELLEP
Sbjct  181  DVLGPERVKPGDVIIAMGSSGLHSNGYSLARNVLLEIDRMNLAGYVEEFGRTLGEELLEP  240

Query  238  TRIYAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQ  297
            TRIYAKDCLAL AET VRTFCHVTGGGLAGNL+RVIPHGL+AE+DRGTWTPAPVF MIAQ
Sbjct  241  TRIYAKDCLALTAETHVRTFCHVTGGGLAGNLERVIPHGLVAEIDRGTWTPAPVFAMIAQ  300

Query  298  RGRVRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKL  357
            RGRV R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTVCKGGK+GPRA L
Sbjct  301  RGRVVREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVCKGGKEGPRATL  360

Query  358  VGQHPRF  364
            VGQHPRF
Sbjct  361  VGQHPRF  367


>gi|145222228|ref|YP_001132906.1| phosphoribosylaminoimidazole synthetase [Mycobacterium gilvum 
PYR-GCK]
 gi|145214714|gb|ABP44118.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
gilvum PYR-GCK]
Length=366

 Score =  624 bits (1608),  Expect = 9e-177, Method: Compositional matrix adjust.
 Identities = 300/351 (86%), Positives = 328/351 (94%), Gaps = 0/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
              GI+YASAGVDIEAGDRA++LFKPLA KATRPEVRG LGGFAGLF LRGDYREP+LA+S
Sbjct  16   QHGISYASAGVDIEAGDRAVELFKPLAKKATRPEVRGDLGGFAGLFALRGDYREPLLASS  75

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLA+AQAMDKHDTVG+DLVAMVVDDLVVCGAEPLFL DYIA+GR VPER++ +V
Sbjct  76   TDGVGTKLAVAQAMDKHDTVGIDLVAMVVDDLVVCGAEPLFLQDYIAIGRTVPERVAELV  135

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            +GIADGC++AGCALLGGETAEHPGL+ PDHYDISATG+GVVEAD+VLGPDRV+PGDVIIA
Sbjct  136  SGIADGCVQAGCALLGGETAEHPGLMAPDHYDISATGIGVVEADDVLGPDRVRPGDVIIA  195

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            M S+GLHSNGYSL R VLLEID MNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET+
Sbjct  196  MASTGLHSNGYSLARHVLLEIDHMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETQ  255

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLAGNL+RVIPHGL+A++DRGTWTPAPVF MIAQRGR+ R EMEKTFNMG
Sbjct  256  VRTFCHVTGGGLAGNLERVIPHGLVAQLDRGTWTPAPVFGMIAQRGRIERAEMEKTFNMG  315

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            VGM+AVVAPEDT RALAVLTARHLDCW LGT+ KG K G RA LVGQHPRF
Sbjct  316  VGMVAVVAPEDTDRALAVLTARHLDCWTLGTIEKGAKDGSRAVLVGQHPRF  366


>gi|315442668|ref|YP_004075547.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
sp. Spyr1]
 gi|315260971|gb|ADT97712.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
sp. Spyr1]
Length=363

 Score =  623 bits (1607),  Expect = 1e-176, Method: Compositional matrix adjust.
 Identities = 300/351 (86%), Positives = 328/351 (94%), Gaps = 0/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
              GI+YASAGVDIEAGDRA++LFKPLA KATRPEVRG LGGFAGLF LRGDYREP+LA+S
Sbjct  13   QHGISYASAGVDIEAGDRAVELFKPLAKKATRPEVRGDLGGFAGLFALRGDYREPLLASS  72

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLA+AQAMDKHDTVG+DLVAMVVDDLVVCGAEPLFL DYIA+GR VPER++ +V
Sbjct  73   TDGVGTKLAVAQAMDKHDTVGIDLVAMVVDDLVVCGAEPLFLQDYIAIGRTVPERVAELV  132

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            +GIADGC++AGCALLGGETAEHPGL+ PDHYDISATG+GVVEAD+VLGPDRV+PGDVIIA
Sbjct  133  SGIADGCVQAGCALLGGETAEHPGLMAPDHYDISATGIGVVEADDVLGPDRVRPGDVIIA  192

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            M S+GLHSNGYSL R VLLEID MNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET+
Sbjct  193  MASTGLHSNGYSLARHVLLEIDHMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETQ  252

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLAGNL+RVIPHGL+A++DRGTWTPAPVF MIAQRGR+ R EMEKTFNMG
Sbjct  253  VRTFCHVTGGGLAGNLERVIPHGLVAQLDRGTWTPAPVFGMIAQRGRIERAEMEKTFNMG  312

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            VGM+AVVAPEDT RALAVLTARHLDCW LGT+ KG K G RA LVGQHPRF
Sbjct  313  VGMVAVVAPEDTDRALAVLTARHLDCWTLGTIEKGAKDGSRAVLVGQHPRF  363


>gi|15828183|ref|NP_302446.1| phosphoribosylaminoimidazole synthetase [Mycobacterium leprae 
TN]
 gi|221230660|ref|YP_002504076.1| phosphoribosylaminoimidazole synthetase [Mycobacterium leprae 
Br4923]
 gi|13093737|emb|CAC31160.1| 5'-phosphoribosyl-5-aminoimidazole synthase [Mycobacterium leprae]
 gi|219933767|emb|CAR72302.1| 5'-phosphoribosyl-5-aminoimidazole synthase [Mycobacterium leprae 
Br4923]
Length=364

 Score =  610 bits (1574),  Expect = 8e-173, Method: Compositional matrix adjust.
 Identities = 317/364 (88%), Positives = 332/364 (92%), Gaps = 0/364 (0%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            M D  K PG   G+ GITYAS GVDIEAGDR+++LFKP+A KA R EV GGLGGFAGLF 
Sbjct  1    MMDPGKSPGGQLGNHGITYASTGVDIEAGDRSVELFKPMAVKAIRTEVLGGLGGFAGLFA  60

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LR  YREPVLAAS+DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  61   LRSGYREPVLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIA  120

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPERLSAIV GIA+GCM AGCALLGGETAEHPGL+E DHYDI+ATGVGVVEAD+ L
Sbjct  121  VGRTVPERLSAIVDGIAEGCMLAGCALLGGETAEHPGLMEVDHYDIAATGVGVVEADDTL  180

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRVKPGDVIIA+ SSGLHSNGYSL R VLLEIDRMNLAG+VEEFGRTLGEELLEPTRI
Sbjct  181  GPDRVKPGDVIIALRSSGLHSNGYSLARSVLLEIDRMNLAGYVEEFGRTLGEELLEPTRI  240

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAET VRTFCHVTGGGLAGNLQRVIPHGL+AEVDRGTWTPAPVF MIAQRGR
Sbjct  241  YAKDCLALAAETHVRTFCHVTGGGLAGNLQRVIPHGLVAEVDRGTWTPAPVFAMIAQRGR  300

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V R EMEKTFNMGVGMIAVVAPEDT RALA+LTARHLDCWVLGTVCKG K GPRAKLVGQ
Sbjct  301  VAREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCWVLGTVCKGSKVGPRAKLVGQ  360

Query  361  HPRF  364
            HPRF
Sbjct  361  HPRF  364


>gi|118467597|ref|YP_890026.1| phosphoribosylaminoimidazole synthetase [Mycobacterium smegmatis 
str. MC2 155]
 gi|118168884|gb|ABK69780.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
smegmatis str. MC2 155]
Length=360

 Score =  608 bits (1569),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 310/351 (89%), Positives = 332/351 (95%), Gaps = 0/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
            S  I+YASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF L+ DYREPVLA+S
Sbjct  10   SDAISYASAGVDIEAGDRAVELFKPLAAKATRPEVRGGLGGFAGLFALKRDYREPVLASS  69

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR VPER+SAIV
Sbjct  70   TDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRTVPERVSAIV  129

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            AGIA+GC+RAGCALLGGETAEHPGL+EPDHYDISATGVG+VEAD+VLGPDRV+PGDVIIA
Sbjct  130  AGIAEGCVRAGCALLGGETAEHPGLMEPDHYDISATGVGIVEADDVLGPDRVRPGDVIIA  189

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            M SSGLHSNGYSL RKVLLEIDRMNLAGHVEEFGRTLGEELLEPT IYAKDCLALAAET+
Sbjct  190  MASSGLHSNGYSLARKVLLEIDRMNLAGHVEEFGRTLGEELLEPTLIYAKDCLALAAETQ  249

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLAGNL+RVIPHGL AE+DRGTWTPAPVF MIAQRGR+ R EMEKTFNMG
Sbjct  250  VRTFCHVTGGGLAGNLERVIPHGLTAELDRGTWTPAPVFGMIAQRGRIERAEMEKTFNMG  309

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            VGM+AVVAPEDT RALA+LTARHL+CW LGTV KGGK   RA+LVGQHPRF
Sbjct  310  VGMVAVVAPEDTDRALAILTARHLNCWTLGTVKKGGKDSVRAQLVGQHPRF  360


>gi|108801501|ref|YP_641698.1| phosphoribosylaminoimidazole synthetase [Mycobacterium sp. MCS]
 gi|119870654|ref|YP_940606.1| phosphoribosylaminoimidazole synthetase [Mycobacterium sp. KMS]
 gi|126437486|ref|YP_001073177.1| phosphoribosylaminoimidazole synthetase [Mycobacterium sp. JLS]
 gi|108771920|gb|ABG10642.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
sp. MCS]
 gi|119696743|gb|ABL93816.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
sp. KMS]
 gi|126237286|gb|ABO00687.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
sp. JLS]
Length=357

 Score =  606 bits (1563),  Expect = 2e-171, Method: Compositional matrix adjust.
 Identities = 306/351 (88%), Positives = 333/351 (95%), Gaps = 0/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
              GI+YASAGVDIEAGDRA++LFKPLA+KATRPEVRGGLGGFAGLF LRG YREPVLA+S
Sbjct  7    QHGISYASAGVDIEAGDRAVELFKPLAAKATRPEVRGGLGGFAGLFALRGGYREPVLASS  66

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR VPER+S +V
Sbjct  67   TDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRTVPERVSQLV  126

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            AGIA+GC+ AGCALLGGETAEHPGL+ PDHYDISATG+G+VEAD+VLGPDRV+PGDVIIA
Sbjct  127  AGIAEGCVIAGCALLGGETAEHPGLMAPDHYDISATGIGIVEADDVLGPDRVRPGDVIIA  186

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            MGSSGLHSNGYSL RKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET+
Sbjct  187  MGSSGLHSNGYSLARKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETQ  246

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLAGNL+RV+P+GL+AE+DRGTWTPAPVF MIAQRGR+ RTEMEKTFNMG
Sbjct  247  VRTFCHVTGGGLAGNLERVVPNGLMAELDRGTWTPAPVFQMIAQRGRIERTEMEKTFNMG  306

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            +GM+AVVAPEDT RALA+LTARH+DCW LGTV KGGK  PRA LVGQHPRF
Sbjct  307  IGMVAVVAPEDTDRALAILTARHIDCWTLGTVKKGGKDEPRALLVGQHPRF  357


>gi|333992191|ref|YP_004524805.1| 5'-phosphoribosyl-5-aminoimidazole synthetase PurM [Mycobacterium 
sp. JDM601]
 gi|333488159|gb|AEF37551.1| 5'-phosphoribosyl-5-aminoimidazole synthetase PurM [Mycobacterium 
sp. JDM601]
Length=363

 Score =  600 bits (1547),  Expect = 1e-169, Method: Compositional matrix adjust.
 Identities = 310/367 (85%), Positives = 337/367 (92%), Gaps = 7/367 (1%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD    P     ++G+TYASAGVDIEAGDRA++LFKPLA++ATRPEVRGGLGGFAGLF 
Sbjct  1    MTD----PAAHSSAQGVTYASAGVDIEAGDRAVELFKPLAARATRPEVRGGLGGFAGLFA  56

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            LR DYREP+LA+S+DGVGTKLAIAQAMDKHDTVG+DLVAMVVDDLVVCGAEPLFL DYIA
Sbjct  57   LRNDYREPLLASSTDGVGTKLAIAQAMDKHDTVGIDLVAMVVDDLVVCGAEPLFLQDYIA  116

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VGR VPER+SAIV+GIA+GC++AGCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VL
Sbjct  117  VGRTVPERVSAIVSGIAEGCVQAGCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVL  176

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPDRV+PGDV+IAMGSSGLHSNGYSL R VLL+IDRMNLAGHVEEFGRTLGEELLEPTRI
Sbjct  177  GPDRVRPGDVLIAMGSSGLHSNGYSLARAVLLDIDRMNLAGHVEEFGRTLGEELLEPTRI  236

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YAKDCLALAAET+VRTFCHVTGGGLAGNL RVIP GLIAEVDRGTWTPAPVF MIAQRGR
Sbjct  237  YAKDCLALAAETQVRTFCHVTGGGLAGNLARVIPDGLIAEVDRGTWTPAPVFGMIAQRGR  296

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQ---GPRAKL  357
            V R EMEKTFN+GVGM+A+VAPEDT RALA+LTARH+DCW LGTV K GK    G  AKL
Sbjct  297  VSRAEMEKTFNLGVGMVAIVAPEDTDRALAILTARHVDCWPLGTVAKAGKSARAGAGAKL  356

Query  358  VGQHPRF  364
            VGQHPRF
Sbjct  357  VGQHPRF  363


>gi|120406059|ref|YP_955888.1| phosphoribosylaminoimidazole synthetase [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958877|gb|ABM15882.1| phosphoribosylformylglycinamidine cyclo-ligase [Mycobacterium 
vanbaalenii PYR-1]
Length=384

 Score =  597 bits (1539),  Expect = 9e-169, Method: Compositional matrix adjust.
 Identities = 302/351 (87%), Positives = 329/351 (94%), Gaps = 0/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
              GI+YASAGVDIEAGDRA++LFKPLA KATRPEVRGGLGGFAGLF LRGDYREP+LA+S
Sbjct  34   QHGISYASAGVDIEAGDRAVELFKPLAKKATRPEVRGGLGGFAGLFALRGDYREPLLASS  93

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLA+AQAMDKHDTVG+DLVAMVVDDLVVCGAEPLFL DYIAVGR VPER++ +V
Sbjct  94   TDGVGTKLAVAQAMDKHDTVGIDLVAMVVDDLVVCGAEPLFLQDYIAVGRTVPERVAELV  153

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            +GIADGC+ AGCALLGGETAEHPGL+ PDHYDISATG+GVVEAD+VLGPDRV+PGDVII 
Sbjct  154  SGIADGCVLAGCALLGGETAEHPGLMAPDHYDISATGIGVVEADDVLGPDRVRPGDVIIG  213

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            M S+GLHSNGYSL R VLLEID MNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET+
Sbjct  214  MASTGLHSNGYSLARHVLLEIDHMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETQ  273

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLAGNL+RVIPHGL+AE+DRGTWTPAPVF MIAQRGR+ R EMEKTFNMG
Sbjct  274  VRTFCHVTGGGLAGNLERVIPHGLVAELDRGTWTPAPVFGMIAQRGRIERAEMEKTFNMG  333

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            VGM+A+VAPEDT RALAVLTARHL+CW LGT+ KGGK GPRA LVGQHPRF
Sbjct  334  VGMVAIVAPEDTDRALAVLTARHLNCWTLGTIEKGGKDGPRAVLVGQHPRF  384


>gi|240172678|ref|ZP_04751337.1| phosphoribosylaminoimidazole synthetase [Mycobacterium kansasii 
ATCC 12478]
Length=341

 Score =  590 bits (1520),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 304/341 (90%), Positives = 325/341 (96%), Gaps = 0/341 (0%)

Query  24   VDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGVGTKLAI  83
            +DI+AGDRA++LFKPLA+KATRPEVRGGLGGFAGLF LRG YREPVLAAS+DGVGTKLA+
Sbjct  1    MDIDAGDRAVELFKPLATKATRPEVRGGLGGFAGLFALRGGYREPVLAASTDGVGTKLAV  60

Query  84   AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIADGCMRA  143
            AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR VPER+SAIV+GIA+GC+RA
Sbjct  61   AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRTVPERVSAIVSGIAEGCVRA  120

Query  144  GCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSSGLHSNG  203
            GCALLGGETAEHPGL+EPDHYDISATGVGVVEAD+VLGP+RVKPGDVIIAMGSSGLHSNG
Sbjct  121  GCALLGGETAEHPGLMEPDHYDISATGVGVVEADDVLGPERVKPGDVIIAMGSSGLHSNG  180

Query  204  YSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTFCHVTGG  263
            YSL R VLLEIDRM+LAG+VEEFGRTLGEELLEPT IYAKDCLALAAET VRTFCHVTGG
Sbjct  181  YSLARAVLLEIDRMSLAGYVEEFGRTLGEELLEPTLIYAKDCLALAAETHVRTFCHVTGG  240

Query  264  GLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMIAVVAPE  323
            GLAGNL+RVIPHGL+AEVDRGTWTPAPVF MIAQRGRV R EMEKTFNMGVGMIAVV PE
Sbjct  241  GLAGNLERVIPHGLVAEVDRGTWTPAPVFAMIAQRGRVVRQEMEKTFNMGVGMIAVVGPE  300

Query  324  DTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            DT RALA+LTARHL+CWVLGTV KGGK GPRA LVG+HPRF
Sbjct  301  DTDRALAILTARHLNCWVLGTVRKGGKDGPRATLVGRHPRF  341


>gi|169627829|ref|YP_001701478.1| phosphoribosylaminoimidazole synthetase [Mycobacterium abscessus 
ATCC 19977]
 gi|169239796|emb|CAM60824.1| Probable phosphoribosylformylglycinamidine cyclo-ligase PurM 
[Mycobacterium abscessus]
Length=362

 Score =  572 bits (1475),  Expect = 3e-161, Method: Compositional matrix adjust.
 Identities = 280/349 (81%), Positives = 310/349 (89%), Gaps = 2/349 (0%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            +YA+AGVDIEAGDRA++LFK   +K  RPEV GG+GGFAGLF L+G YREPVLAAS+DGV
Sbjct  14   SYAAAGVDIEAGDRAVELFKKSVAKTHRPEVLGGIGGFAGLFALKGGYREPVLAASTDGV  73

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTK+A+AQAMDK DTVGLDLVAMVVDDLVVCGAEPLFL DYIAVG++VPER+S +VAGIA
Sbjct  74   GTKIAVAQAMDKRDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGKVVPERVSELVAGIA  133

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            +GC  AGCALLGGETAEHPGL+ PD +D+SATGVG+VEAD VLGPDRV+PGDV+IAMGSS
Sbjct  134  EGCAIAGCALLGGETAEHPGLMAPDDFDLSATGVGIVEADRVLGPDRVRPGDVVIAMGSS  193

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL R VLLEIDRM+L G VEEFGRTLGEELLEPTRIYAKDCLALAAET VRTF
Sbjct  194  GLHSNGYSLARHVLLEIDRMDLFGQVEEFGRTLGEELLEPTRIYAKDCLALAAETEVRTF  253

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
            CHVTGGGLAGNL RVIP GL+AE+DRG+WTP P+F MIAQRGR+ R EMEKTFNMGVGM+
Sbjct  254  CHVTGGGLAGNLARVIPDGLVAELDRGSWTPGPIFAMIAQRGRIERAEMEKTFNMGVGMV  313

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQ--GPRAKLVGQHPRF  364
            AVVAPED  RALAVLTARH+DCW LGT+ K GK      A LVGQHPRF
Sbjct  314  AVVAPEDVDRALAVLTARHIDCWTLGTIKKSGKDSGSESALLVGQHPRF  362


>gi|54022547|ref|YP_116789.1| phosphoribosylaminoimidazole synthetase [Nocardia farcinica IFM 
10152]
 gi|54014055|dbj|BAD55425.1| putative phosphoribosylaminoimidazole synthetase [Nocardia farcinica 
IFM 10152]
Length=358

 Score =  559 bits (1441),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 284/350 (82%), Positives = 319/350 (92%), Gaps = 1/350 (0%)

Query  16   GITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSD  75
            G +YA+AGVDIEAGDRA++LF PLA KATRPEV+GGLGGFAGLF L+G YREP+LAAS+D
Sbjct  9    GASYAAAGVDIEAGDRAVELFGPLAKKATRPEVQGGLGGFAGLFALKGGYREPLLAASTD  68

Query  76   GVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAG  135
            GVGTK+A+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIA+G++VPE+++ +V+G
Sbjct  69   GVGTKIAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAIGKVVPEKVAELVSG  128

Query  136  IADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMG  195
            IA+GC+RAGCALLGGETAEHPGL++PD YD+SATGVGVVEAD VLGPDRV+PGDV+IAMG
Sbjct  129  IAEGCVRAGCALLGGETAEHPGLMDPDDYDLSATGVGVVEADAVLGPDRVRPGDVVIAMG  188

Query  196  SSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVR  255
            SSGLHSNGYSL RKVLL+IDRM+L GHVEEFGRTLGEELLEPTRIYAKDCLAL AET VR
Sbjct  189  SSGLHSNGYSLARKVLLDIDRMSLTGHVEEFGRTLGEELLEPTRIYAKDCLALIAETDVR  248

Query  256  TFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVG  315
            TF HVTGGGLA NL RVIP GL+AE+DRGTW PAPVF MIAQRGRV R EMEKTFNMGVG
Sbjct  249  TFAHVTGGGLAANLARVIPAGLVAELDRGTWNPAPVFKMIAQRGRVERAEMEKTFNMGVG  308

Query  316  MIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            M+AVVAPED  RALAVLTARH++CW LGTV K      PRA+L+G+HPRF
Sbjct  309  MVAVVAPEDVDRALAVLTARHIECWTLGTVKKAKDADAPRAELLGEHPRF  358


>gi|312138305|ref|YP_004005641.1| phosphoribosylformylglycinamidine cyclo-ligase purm [Rhodococcus 
equi 103S]
 gi|325674778|ref|ZP_08154465.1| phosphoribosylaminoimidazole synthetase [Rhodococcus equi ATCC 
33707]
 gi|311887644|emb|CBH46956.1| phosphoribosylformylglycinamidine cyclo-ligase PurM [Rhodococcus 
equi 103S]
 gi|325554364|gb|EGD24039.1| phosphoribosylaminoimidazole synthetase [Rhodococcus equi ATCC 
33707]
Length=386

 Score =  556 bits (1433),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 280/352 (80%), Positives = 318/352 (91%), Gaps = 1/352 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
            ++G +YA+AGVDIEAGDRA++LF PLA KA+RPEV GGLGGFAGLF+L+GDY+EP+LAAS
Sbjct  35   TQGASYAAAGVDIEAGDRAVELFAPLAKKASRPEVMGGLGGFAGLFSLKGDYKEPLLAAS  94

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            +DGVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR+VPER++ IV
Sbjct  95   TDGVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRVVPERVAEIV  154

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
             GIA+GC++AGCALLGGETAEHPG++    YDISATGVGVVEAD VLGPDRV+PGDV+I 
Sbjct  155  GGIAEGCIQAGCALLGGETAEHPGVMADGDYDISATGVGVVEADQVLGPDRVRPGDVVIG  214

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            MG+SGLHSNGYSL RKVLLEIDRM+L GHV+EFGRTLGEELLEPT+IYAKDCLALAAET 
Sbjct  215  MGASGLHSNGYSLARKVLLEIDRMSLTGHVDEFGRTLGEELLEPTKIYAKDCLALAAETD  274

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            VRTFCHVTGGGLA NL RV+P GL+AE+DRGTW+PAP+FTMIAQRGRV R EME+TFNMG
Sbjct  275  VRTFCHVTGGGLANNLARVMPKGLVAELDRGTWSPAPIFTMIAQRGRVERAEMEQTFNMG  334

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            VGM+A+VAPED  RA+AVLTARH+DCW LGTV K       RA L+G HPRF
Sbjct  335  VGMVAIVAPEDVDRAMAVLTARHIDCWTLGTVKKASDGDAARALLLGDHPRF  386


>gi|226308311|ref|YP_002768271.1| aminoimidazole ribonucleotide synthetase [Rhodococcus erythropolis 
PR4]
 gi|229488865|ref|ZP_04382731.1| phosphoribosylformylglycinamidine cyclo-ligase [Rhodococcus erythropolis 
SK121]
 gi|226187428|dbj|BAH35532.1| aminoimidazole ribonucleotide synthetase [Rhodococcus erythropolis 
PR4]
 gi|229324369|gb|EEN90124.1| phosphoribosylformylglycinamidine cyclo-ligase [Rhodococcus erythropolis 
SK121]
Length=359

 Score =  552 bits (1423),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 277/350 (80%), Positives = 315/350 (90%), Gaps = 1/350 (0%)

Query  16   GITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSD  75
            G +YA+AGVDI AGDRA++LF PLA KA+RPEV GGLGGFAGLF+L+GDY+EP+LAAS+D
Sbjct  10   GASYAAAGVDIAAGDRAVELFAPLAKKASRPEVMGGLGGFAGLFSLKGDYKEPLLAASTD  69

Query  76   GVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAG  135
            GVGTKLA+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR++PER++ +V+G
Sbjct  70   GVGTKLAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRVIPERVAELVSG  129

Query  136  IADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMG  195
            IA+GC++AGCALLGGETAEHPG++    YD+SATGVGVVEA+ +LGPDRV+PGDV+IAMG
Sbjct  130  IAEGCIQAGCALLGGETAEHPGIMADGDYDLSATGVGVVEAEKLLGPDRVRPGDVVIAMG  189

Query  196  SSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVR  255
            SSGLHSNGYSL RKVLLEIDRMNL+ HV+EFGRTLGEELLEPT+IYAKDCLALAAET VR
Sbjct  190  SSGLHSNGYSLARKVLLEIDRMNLSAHVDEFGRTLGEELLEPTKIYAKDCLALAAETDVR  249

Query  256  TFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVG  315
            TFCHVTGGGLA NL RV+P GL+AE+DRGTW+PAPVF MIAQRGRV R EME+TFNMGVG
Sbjct  250  TFCHVTGGGLANNLARVMPKGLVAELDRGTWSPAPVFAMIAQRGRVERAEMEQTFNMGVG  309

Query  316  MIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            M+AVVAPED  RALAVLTARH+DCW LG+V K       RA L G HPRF
Sbjct  310  MVAVVAPEDVDRALAVLTARHIDCWTLGSVKKASDAAAERAFLAGDHPRF  359


>gi|111021812|ref|YP_704784.1| phosphoribosylaminoimidazole synthetase [Rhodococcus jostii RHA1]
 gi|226364334|ref|YP_002782116.1| phosphoribosylaminoimidazole synthetase [Rhodococcus opacus B4]
 gi|110821342|gb|ABG96626.1| phosphoribosylformylglycinamidine cyclo-ligase [Rhodococcus jostii 
RHA1]
 gi|226242823|dbj|BAH53171.1| aminoimidazole ribonucleotide synthetase [Rhodococcus opacus 
B4]
Length=359

 Score =  549 bits (1414),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 276/357 (78%), Positives = 318/357 (90%), Gaps = 2/357 (0%)

Query  10   KDPGSR-GITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREP  68
            +DP SR G +YA+AGVDI AGDRA++LF PLA +A+RPEV GGLGGFAGLF+L+GDY+EP
Sbjct  3    EDPTSRPGASYAAAGVDIAAGDRAVELFAPLAKRASRPEVLGGLGGFAGLFSLKGDYKEP  62

Query  69   VLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPER  128
            +LAAS+DGVGTKLA+AQA+DKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVGR+VPER
Sbjct  63   LLAASTDGVGTKLAVAQALDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGRVVPER  122

Query  129  LSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPG  188
            ++ +V+GIA+GC++AGCALLGGETAEHPG++    YD+SATGVGVVEAD VLGPDRV+PG
Sbjct  123  VAELVSGIAEGCIQAGCALLGGETAEHPGVMADGDYDLSATGVGVVEADQVLGPDRVRPG  182

Query  189  DVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLAL  248
            DV+IAMGSSGLHSNGYSL RKVLLEID M+L  HV+EFGRTLGEE+LEPT+IYAKDCLAL
Sbjct  183  DVVIAMGSSGLHSNGYSLARKVLLEIDHMSLTAHVDEFGRTLGEEMLEPTKIYAKDCLAL  242

Query  249  AAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEK  308
            AAET VRTFCHVTGGGLA NL RV+P GL+AE+DRGTW+PAP+F MIAQRGRV R EME+
Sbjct  243  AAETDVRTFCHVTGGGLANNLARVMPKGLVAELDRGTWSPAPIFAMIAQRGRVERAEMEQ  302

Query  309  TFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            TFNMGVGM+A+VAPED  RALAVLTARH+DCW LG++ K       RA L G HPRF
Sbjct  303  TFNMGVGMVAIVAPEDVDRALAVLTARHIDCWTLGSIKKSHDVSAERAILAGDHPRF  359


>gi|326384542|ref|ZP_08206221.1| phosphoribosylaminoimidazole synthetase [Gordonia neofelifaecis 
NRRL B-59395]
 gi|326196676|gb|EGD53871.1| phosphoribosylaminoimidazole synthetase [Gordonia neofelifaecis 
NRRL B-59395]
Length=361

 Score =  530 bits (1365),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 270/355 (77%), Positives = 312/355 (88%), Gaps = 1/355 (0%)

Query  11   DPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVL  70
            D  + G +YA+AGVDI+AG+RA++LF P A +ATRPEV GGLGGFAGLF+L+GDYREPVL
Sbjct  7    DKPTTGASYAAAGVDIDAGERAVELFAPHAKRATRPEVLGGLGGFAGLFSLKGDYREPVL  66

Query  71   AASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLS  130
            A+SSDGVGTKL IAQAMDKHDTVG DLVAMVVDDLVVCGAEPLFL DYIA+G+++PE ++
Sbjct  67   ASSSDGVGTKLVIAQAMDKHDTVGRDLVAMVVDDLVVCGAEPLFLQDYIAIGKVIPEMVA  126

Query  131  AIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDV  190
             IV GIADGC+ AGCALLGGETAEHPG++E  HYDISATGVGVVEAD++LGPDRV+ GDV
Sbjct  127  DIVKGIADGCVDAGCALLGGETAEHPGVMEDGHYDISATGVGVVEADSILGPDRVRAGDV  186

Query  191  IIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAA  250
            +IAMGSSGLHSNGYSL RKVLL+   M+L+GHVEEFGR+LGEELLEPTRIYAKDCLALAA
Sbjct  187  VIAMGSSGLHSNGYSLARKVLLDWGHMDLSGHVEEFGRSLGEELLEPTRIYAKDCLALAA  246

Query  251  ETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTF  310
            E+ VRTF HVTGGGLA NL RV+P GL AE++R TWTPAP+F++IAQRGRV R EME+TF
Sbjct  247  ESDVRTFAHVTGGGLADNLSRVLPKGLSAELERNTWTPAPIFSLIAQRGRVERVEMERTF  306

Query  311  NMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPR-AKLVGQHPRF  364
            NMGVGM+A+VAPEDT RA A+LTARH+D WVLGT+ +G    P  A LVG HPRF
Sbjct  307  NMGVGMVAIVAPEDTDRAQAILTARHVDNWVLGTIKRGEPGAPSAATLVGDHPRF  361


>gi|333918373|ref|YP_004491954.1| phosphoribosylformylglycinamidine cyclo-ligase [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333480594|gb|AEF39154.1| Phosphoribosylformylglycinamidine cyclo-ligase [Amycolicicoccus 
subflavus DQS3-9A1]
Length=362

 Score =  527 bits (1358),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 267/353 (76%), Positives = 311/353 (89%), Gaps = 4/353 (1%)

Query  16   GITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSD  75
            G +YA++GVDI+AG+RA++LFKPLA KATRPEV GGLGGFAGLF L+  YREP+LAAS+D
Sbjct  10   GASYAASGVDIDAGERAVELFKPLAKKATRPEVVGGLGGFAGLFALKDKYREPLLAASTD  69

Query  76   GVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAG  135
            GVGTK+A+AQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFL DYIAVG++VPE+++ IV+G
Sbjct  70   GVGTKIAVAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLQDYIAVGKVVPEKVAQIVSG  129

Query  136  IADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMG  195
            IA+GC++AGCALLGGETAEHPGL+    YD+SATGVGVVEAD+VLGPDRV+PGDV+IAM 
Sbjct  130  IAEGCVQAGCALLGGETAEHPGLMGDSDYDLSATGVGVVEADSVLGPDRVRPGDVVIAMA  189

Query  196  SSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVR  255
            SSGLHSNGYSL R+VLLEI+RM+L GHVEEFGRTLGEELLEPTRIYA+DCLA+ AET VR
Sbjct  190  SSGLHSNGYSLARRVLLEINRMSLTGHVEEFGRTLGEELLEPTRIYARDCLAVIAETDVR  249

Query  256  TFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVG  315
            TF HVTGGGL  NL RV+P GL+AE+DRGTW+PAP+F MI+QRGRV   EME+TFNMGVG
Sbjct  250  TFAHVTGGGLGENLSRVMPRGLVAELDRGTWSPAPIFRMISQRGRVETAEMERTFNMGVG  309

Query  316  MIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK----QGPRAKLVGQHPRF  364
            M+AVVAP+D  R LAVLTARH+ CW +GTV K  +       RA LVG+HPRF
Sbjct  310  MVAVVAPDDVDRTLAVLTARHMSCWTIGTVRKANEVHAGDDVRAILVGEHPRF  362


>gi|291008351|ref|ZP_06566324.1| phosphoribosylaminoimidazole synthetase [Saccharopolyspora erythraea 
NRRL 2338]
Length=371

 Score =  526 bits (1355),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 264/368 (72%), Positives = 303/368 (83%), Gaps = 6/368 (1%)

Query  3    DLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLR  62
            DL  G   +      TYA+AGV IEAGD+A++L KP A +ATRPEV G LGGFAGLF L+
Sbjct  4    DLLSGSSVNNEQPSATYAAAGVSIEAGDQAVELIKPWAQRATRPEVLGSLGGFAGLFQLK  63

Query  63   GD-YREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAV  121
             D ++EPVLA+S+DGVGTKLA+AQA+D HDT+G+DLVAMVVDDLVVCGAEPLFL DYIAV
Sbjct  64   LDRWKEPVLASSTDGVGTKLAVAQALDLHDTIGIDLVAMVVDDLVVCGAEPLFLQDYIAV  123

Query  122  GRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLG  181
            G++VPER++A+V GI++GC++AGCALLGGETAEHPGL+    YD+SATGVGVVEAD++LG
Sbjct  124  GKVVPERVAAVVKGISEGCVQAGCALLGGETAEHPGLMGEGEYDVSATGVGVVEADSMLG  183

Query  182  PDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIY  241
            PDRV+PGDV+IAMGSSGLHSNGYSL RKVLL+I RM L+GHVEEFGRTLGEELLEPTRIY
Sbjct  184  PDRVRPGDVVIAMGSSGLHSNGYSLARKVLLDIARMPLSGHVEEFGRTLGEELLEPTRIY  243

Query  242  AKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRV  301
            AKDCLALAAE  VRTF HVTGGGLA NL RV+P GL A +DRGTWTP PVF +IAQRGRV
Sbjct  244  AKDCLALAAEAEVRTFAHVTGGGLAANLARVVPEGLTAVLDRGTWTPDPVFRLIAQRGRV  303

Query  302  RRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKG-----GKQGPRAK  356
               EME+TFNMGVGM+AVV  ED  RALAVLTARH+  WVLG V K        +  R  
Sbjct  304  DTAEMEQTFNMGVGMVAVVTAEDVDRALAVLTARHVPAWVLGEVAKQPTVEEAGEHDRVV  363

Query  357  LVGQHPRF  364
            L G HPRF
Sbjct  364  LRGNHPRF  371


>gi|134103546|ref|YP_001109207.1| phosphoribosylaminoimidazole synthetase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133916169|emb|CAM06282.1| phosphoribosylformylglycinamidine cyclo-ligase [Saccharopolyspora 
erythraea NRRL 2338]
Length=361

 Score =  523 bits (1348),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 261/353 (74%), Positives = 299/353 (85%), Gaps = 6/353 (1%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGD-YREPVLAASSDG  76
            TYA+AGV IEAGD+A++L KP A +ATRPEV G LGGFAGLF L+ D ++EPVLA+S+DG
Sbjct  9    TYAAAGVSIEAGDQAVELIKPWAQRATRPEVLGSLGGFAGLFQLKLDRWKEPVLASSTDG  68

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTKLA+AQA+D HDT+G+DLVAMVVDDLVVCGAEPLFL DYIAVG++VPER++A+V GI
Sbjct  69   VGTKLAVAQALDLHDTIGIDLVAMVVDDLVVCGAEPLFLQDYIAVGKVVPERVAAVVKGI  128

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            ++GC++AGCALLGGETAEHPGL+    YD+SATGVGVVEAD++LGPDRV+PGDV+IAMGS
Sbjct  129  SEGCVQAGCALLGGETAEHPGLMGEGEYDVSATGVGVVEADSMLGPDRVRPGDVVIAMGS  188

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            SGLHSNGYSL RKVLL+I RM L+GHVEEFGRTLGEELLEPTRIYAKDCLALAAE  VRT
Sbjct  189  SGLHSNGYSLARKVLLDIARMPLSGHVEEFGRTLGEELLEPTRIYAKDCLALAAEAEVRT  248

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            F HVTGGGLA NL RV+P GL A +DRGTWTP PVF +IAQRGRV   EME+TFNMGVGM
Sbjct  249  FAHVTGGGLAANLARVVPEGLTAVLDRGTWTPDPVFRLIAQRGRVDTAEMEQTFNMGVGM  308

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTVCKG-----GKQGPRAKLVGQHPRF  364
            +AVV  ED  RALAVLTARH+  WVLG V K        +  R  L G HPRF
Sbjct  309  VAVVTAEDVDRALAVLTARHVPAWVLGEVAKQPTVEEAGEHDRVVLRGNHPRF  361


>gi|256380840|ref|YP_003104500.1| phosphoribosylaminoimidazole synthetase [Actinosynnema mirum 
DSM 43827]
 gi|255925143|gb|ACU40654.1| phosphoribosylformylglycinamidine cyclo-ligase [Actinosynnema 
mirum DSM 43827]
Length=357

 Score =  522 bits (1344),  Expect = 4e-146, Method: Compositional matrix adjust.
 Identities = 261/348 (75%), Positives = 298/348 (86%), Gaps = 4/348 (1%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGD-YREPVLAASSDG  76
            TYA+AGV IEAGD A++  KP A+KA RPEV GG+GGFAGLF L+ D ++EPVLA+S+DG
Sbjct  13   TYAAAGVSIEAGDEAVEKLKPWAAKAHRPEVLGGIGGFAGLFQLKLDRWKEPVLASSTDG  72

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTK+A+AQA+DKHDTVG+DLVAMVVDDLVVCGAEPLFL DYIAVGR+VP+R++A+V GI
Sbjct  73   VGTKIAVAQALDKHDTVGIDLVAMVVDDLVVCGAEPLFLQDYIAVGRVVPDRIAALVKGI  132

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            A+GC++AGCALLGGETAEHPGL+    YDIS TGVGVVEA  +LGPDRV+ GDV+IAMGS
Sbjct  133  AEGCVQAGCALLGGETAEHPGLMADGDYDISGTGVGVVEASAMLGPDRVRDGDVVIAMGS  192

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            SGLHSNGYSL R VLLEI RM L GHVEEFGRTLGEE+LEPTRIYAKDCLALAAE  VRT
Sbjct  193  SGLHSNGYSLARHVLLEIARMPLEGHVEEFGRTLGEEMLEPTRIYAKDCLALAAEAEVRT  252

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            F H+TGGGLA NL RV+P GL A +DRGTWTPAPVF +IAQRGRV R EMEKTFNMG+GM
Sbjct  253  FAHITGGGLAANLARVLPEGLHARLDRGTWTPAPVFALIAQRGRVEREEMEKTFNMGIGM  312

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            +AVV+PED  R+LAVLTARH+  WVLG V   G+ G  A L G HPRF
Sbjct  313  VAVVSPEDVDRSLAVLTARHVPAWVLGEVT-AGETG--AVLAGDHPRF  357


>gi|344046352|gb|EGV42018.1| phosphoribosylaminoimidazole synthetase [Corynebacterium glutamicum 
S9114]
Length=358

 Score =  519 bits (1337),  Expect = 3e-145, Method: Compositional matrix adjust.
 Identities = 251/355 (71%), Positives = 297/355 (84%), Gaps = 1/355 (0%)

Query  10   KDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPV  69
            +D  + G++YA+AGVDIEAGDRA++LF P+A +ATRPEV G LGGFAGLF L G Y++P+
Sbjct  5    QDTTAEGVSYAAAGVDIEAGDRAVELFAPMAKRATRPEVLGNLGGFAGLFEL-GKYKKPI  63

Query  70   LAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERL  129
            LAA SDGVGTKL IAQ MDKHDT+G+DLVAM VDDLVV GAEPLFL DYIA+G++VPE +
Sbjct  64   LAAGSDGVGTKLVIAQMMDKHDTIGIDLVAMCVDDLVVTGAEPLFLQDYIAIGKVVPEHV  123

Query  130  SAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGD  189
            + IV+GIA+GC++AGCALLGGETAEHPG++EPDHYD+SAT VGVVEAD +LGPDRV+ GD
Sbjct  124  AEIVSGIAEGCVQAGCALLGGETAEHPGVMEPDHYDVSATAVGVVEADELLGPDRVRAGD  183

Query  190  VIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALA  249
            V+I M SSGLHSNGYSL R VLLE   + L GH+EE GRTLGEELLEPTRIYAKDCLAL 
Sbjct  184  VLIGMASSGLHSNGYSLARHVLLEKAGLALDGHIEELGRTLGEELLEPTRIYAKDCLALI  243

Query  250  AETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKT  309
            AE  V TFCHVTGGGLAGNL+RVIP GL+AE+ R TWTP+ +F  I+  G+V R EMEKT
Sbjct  244  AECEVHTFCHVTGGGLAGNLERVIPEGLVAEMSRATWTPSQIFRTISSVGKVSREEMEKT  303

Query  310  FNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            FNMGVGM+AVVA +D  RALA+LTARH+DCW +GTV  G +  PR  L G+HP +
Sbjct  304  FNMGVGMVAVVAEKDRDRALAMLTARHIDCWEIGTVRNGEEGEPRVILNGEHPGY  358


>gi|145296578|ref|YP_001139399.1| phosphoribosylaminoimidazole synthetase [Corynebacterium glutamicum 
R]
 gi|57157714|dbj|BAD83821.1| phosphoribosylaminoimidazole synthase [Corynebacterium glutamicum]
 gi|140846498|dbj|BAF55497.1| hypothetical protein [Corynebacterium glutamicum R]
Length=358

 Score =  519 bits (1336),  Expect = 4e-145, Method: Compositional matrix adjust.
 Identities = 251/355 (71%), Positives = 296/355 (84%), Gaps = 1/355 (0%)

Query  10   KDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPV  69
            +D  + G++YA+AGVDIEAGDRA++LF P+A +ATRPEV G LGGFAGLF L G Y++P+
Sbjct  5    QDTTAEGVSYAAAGVDIEAGDRAVELFAPMAKRATRPEVLGNLGGFAGLFEL-GKYKKPI  63

Query  70   LAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERL  129
            LAA SDGVGTKL IAQ MDKHDT+G+DLVAM VDDLVV GAEPLFL DYIA+G++VPE +
Sbjct  64   LAAGSDGVGTKLVIAQMMDKHDTIGIDLVAMCVDDLVVTGAEPLFLQDYIAIGKVVPEHV  123

Query  130  SAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGD  189
            + IV+GIA+GC++AGCALLGGETAEHPG++EPDHYD+SAT VGVVEAD +LGPDRV+ GD
Sbjct  124  AEIVSGIAEGCVQAGCALLGGETAEHPGVMEPDHYDVSATAVGVVEADELLGPDRVRAGD  183

Query  190  VIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALA  249
            V+I M SSGLHSNGYSL R VLLE   + L GH+EE GRTLGEELLEPTRIYAKDCLAL 
Sbjct  184  VLIGMASSGLHSNGYSLARHVLLEKAGLALDGHIEELGRTLGEELLEPTRIYAKDCLALI  243

Query  250  AETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKT  309
            AE  V TFCHVTGGGLAGNL+RVIP GL+AE+ R TWTP  +F  I+  G+V R EMEKT
Sbjct  244  AECEVHTFCHVTGGGLAGNLERVIPEGLVAEMSRATWTPGQIFRTISSVGKVSREEMEKT  303

Query  310  FNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            FNMGVGM+AVVA +D  RALA+LTARH+DCW +GTV  G +  PR  L G+HP +
Sbjct  304  FNMGVGMVAVVAEKDRDRALAMLTARHIDCWEIGTVRNGEEGEPRVILNGEHPGY  358


>gi|19553779|ref|NP_601781.1| phosphoribosylaminoimidazole synthetase [Corynebacterium glutamicum 
ATCC 13032]
 gi|62391422|ref|YP_226824.1| phosphoribosylaminoimidazole synthetase [Corynebacterium glutamicum 
ATCC 13032]
 gi|21325355|dbj|BAB99976.1| Phosphoribosylaminoimidazol (AIR) synthetase [Corynebacterium 
glutamicum ATCC 13032]
 gi|41326763|emb|CAF21245.1| PHOSPHORIBOSYL AMINOIMIDAZOLE SYNTHETASE [Corynebacterium glutamicum 
ATCC 13032]
Length=358

 Score =  518 bits (1334),  Expect = 6e-145, Method: Compositional matrix adjust.
 Identities = 250/355 (71%), Positives = 296/355 (84%), Gaps = 1/355 (0%)

Query  10   KDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPV  69
            +D  + G++YA+AGVDIEAGDRA++LF P+A +ATRPEV G LGGFAGLF L G Y++P+
Sbjct  5    QDTTAEGVSYAAAGVDIEAGDRAVELFAPMAKRATRPEVLGNLGGFAGLFEL-GKYKKPI  63

Query  70   LAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERL  129
            LAA SDGVGTKL IAQ MDKHDT+G+DLVAM VDDLVV GAEPLFL DYIA+G++VPE +
Sbjct  64   LAAGSDGVGTKLVIAQMMDKHDTIGIDLVAMCVDDLVVTGAEPLFLQDYIAIGKVVPEHV  123

Query  130  SAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGD  189
            + IV+GIA+GC++AGCALLGGETAEHPG++EPDHYD+SAT VGVVEAD +LGPDRV+ GD
Sbjct  124  AEIVSGIAEGCVQAGCALLGGETAEHPGVMEPDHYDVSATAVGVVEADELLGPDRVRAGD  183

Query  190  VIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALA  249
            V+I M SSGLHSNGYSL R VLLE   + L GH+EE GRTLGEELLEPTRIYAKDCLAL 
Sbjct  184  VLIGMASSGLHSNGYSLARHVLLEKAGLALDGHIEELGRTLGEELLEPTRIYAKDCLALI  243

Query  250  AETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKT  309
            AE  V TFCHVTGGGLAGNL+RV+P GL+AE+ R TWTP  +F  I+  G+V R EMEKT
Sbjct  244  AECEVHTFCHVTGGGLAGNLERVVPEGLVAEMSRATWTPGQIFRTISSVGKVSREEMEKT  303

Query  310  FNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            FNMGVGM+AVVA +D  RALA+LTARH+DCW +GTV  G +  PR  L G+HP +
Sbjct  304  FNMGVGMVAVVAEKDRDRALAMLTARHIDCWEIGTVRNGEEGEPRVILNGEHPGY  358


>gi|262200945|ref|YP_003272153.1| phosphoribosylformylglycinamidine cyclo-ligase [Gordonia bronchialis 
DSM 43247]
 gi|262084292|gb|ACY20260.1| phosphoribosylformylglycinamidine cyclo-ligase [Gordonia bronchialis 
DSM 43247]
Length=369

 Score =  517 bits (1332),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 261/351 (75%), Positives = 306/351 (88%), Gaps = 4/351 (1%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            +YA+AGVDI+AG+RA++LF P A +A+RPEV GGLGGF+GLF L+G+YREPVLAA+SDGV
Sbjct  19   SYAAAGVDIDAGERAVELFAPHAKRASRPEVMGGLGGFSGLFALKGNYREPVLAAASDGV  78

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTKLAIAQA+DKHDTVG DLVAM VDDLVVCGAEPLFL DYIAVG+++PE ++ IV+GIA
Sbjct  79   GTKLAIAQAIDKHDTVGRDLVAMCVDDLVVCGAEPLFLQDYIAVGKVIPETVAQIVSGIA  138

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            DGC+ AGCALLGGETAEHPGL++ +HYD+SAT VGVVEAD VL PD+V+ GDV+I MGSS
Sbjct  139  DGCVDAGCALLGGETAEHPGLMQDNHYDLSATAVGVVEADEVLSPDKVRAGDVVIGMGSS  198

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL RKVLLE   M+L GHVEEFGRTLGEELLEPTRIYA+DCLAL AE  VRT+
Sbjct  199  GLHSNGYSLARKVLLEWGHMDLFGHVEEFGRTLGEELLEPTRIYARDCLALTAEADVRTY  258

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
             H+TGGGLA NL RVIP GL+AE++R TW+PAP+F+MIAQRGRV + EME+TFNMGVGM+
Sbjct  259  AHITGGGLAENLARVIPSGLVAELERNTWSPAPIFSMIAQRGRVAQPEMERTFNMGVGMV  318

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQ----GPRAKLVGQHPRF  364
            AVVAPEDT RA AVLTARH+D WVLGTV + G++      R  LVG+HPRF
Sbjct  319  AVVAPEDTDRAQAVLTARHVDNWVLGTVKRSGERKQSDAARVTLVGEHPRF  369


>gi|343925899|ref|ZP_08765414.1| aminoimidazole ribonucleotide synthetase [Gordonia alkanivorans 
NBRC 16433]
 gi|343764250|dbj|GAA12340.1| aminoimidazole ribonucleotide synthetase [Gordonia alkanivorans 
NBRC 16433]
Length=370

 Score =  515 bits (1327),  Expect = 4e-144, Method: Compositional matrix adjust.
 Identities = 262/352 (75%), Positives = 303/352 (87%), Gaps = 5/352 (1%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            +YA+AGVDI+AG+RA++L  P A +A+RPEV GGLGGF+GLF L+G+YREPVLAA+SDGV
Sbjct  19   SYAAAGVDIDAGERAVELITPHAKRASRPEVLGGLGGFSGLFALKGNYREPVLAAASDGV  78

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTKLA+AQA+DKHDTVG DLVAM VDDLVVCGAEPLFL DYIAVG++VPE ++ IVAGIA
Sbjct  79   GTKLAVAQAIDKHDTVGRDLVAMCVDDLVVCGAEPLFLQDYIAVGKVVPETVAQIVAGIA  138

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            DGC+ AGCALLGGETAEHPGL++ +HYD+SAT VGVVEAD VL PDRV+ GDV+IAMGSS
Sbjct  139  DGCVEAGCALLGGETAEHPGLMQDNHYDLSATAVGVVEADKVLTPDRVRAGDVVIAMGSS  198

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL RKVLLE   M+L GHVEEFGR+LGEELLEPTRIYA+DCLAL AE  VRTF
Sbjct  199  GLHSNGYSLARKVLLEWGHMDLFGHVEEFGRSLGEELLEPTRIYARDCLALIAEADVRTF  258

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
             H+TGGGLA NL RVIP GL+AE++R TWTPAP+F +I QRGRV + EME+TFNMGVGM+
Sbjct  259  AHITGGGLAENLARVIPQGLVAELERNTWTPAPIFALIGQRGRVEQLEMERTFNMGVGMV  318

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVC-----KGGKQGPRAKLVGQHPRF  364
            AVVAPEDT RA AVLTARH+D WVLGT+      K  + G R  LVG+HPRF
Sbjct  319  AVVAPEDTDRAQAVLTARHVDNWVLGTIKRSTDPKNTEAGSRVSLVGEHPRF  370


>gi|302531031|ref|ZP_07283373.1| phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces 
sp. AA4]
 gi|302439926|gb|EFL11742.1| phosphoribosylformylglycinamidine cyclo-ligase [Streptomyces 
sp. AA4]
Length=356

 Score =  515 bits (1327),  Expect = 4e-144, Method: Compositional matrix adjust.
 Identities = 249/353 (71%), Positives = 301/353 (86%), Gaps = 2/353 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGD-YREPVLAA  72
            S   TYA+AGV I+AGD+A++L KP A +ATRPEVRGG+GGFAGLF+L+ D ++EP+LA+
Sbjct  4    STSATYAAAGVSIDAGDQAVELLKPHAERATRPEVRGGVGGFAGLFSLKLDKWKEPILAS  63

Query  73   SSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAI  132
            S+DGVGTK+A+AQA+DKHDTVG+DLVAMVVDDLVV GAEPLFL DYIAVG++VPE+++A+
Sbjct  64   STDGVGTKIAVAQALDKHDTVGIDLVAMVVDDLVVTGAEPLFLQDYIAVGKVVPEKIAAL  123

Query  133  VAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVII  192
            V GIA+GC++AGCALLGGETAEHPGL+    YD+SATGVG VEA  +L P++V+PGDV++
Sbjct  124  VGGIAEGCVQAGCALLGGETAEHPGLMGEHDYDLSATGVGAVEASALLSPEKVRPGDVVL  183

Query  193  AMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET  252
            AMGSSGLHSNGYSL R VLL+I RM L GHVEEFGRTLGEELLEPT+IYAKDCLAL AET
Sbjct  184  AMGSSGLHSNGYSLARHVLLDIARMPLDGHVEEFGRTLGEELLEPTKIYAKDCLALVAET  243

Query  253  RVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNM  312
             VRTF H+TGGGL  NL RV+P GL+A+++RGTWTPAPVF +I QRG+V R E+EKTFNM
Sbjct  244  EVRTFAHITGGGLEANLARVMPRGLVAKLERGTWTPAPVFALIGQRGKVERAELEKTFNM  303

Query  313  GVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKG-GKQGPRAKLVGQHPRF  364
            GVGM+A+V+ ED  RALAVLTARH+  W+LG +       GPRA L G HPRF
Sbjct  304  GVGMVAIVSSEDVDRALAVLTARHVPAWILGDIQPAEDPDGPRAVLSGDHPRF  356


>gi|25029031|ref|NP_739085.1| phosphoribosylaminoimidazole synthetase [Corynebacterium efficiens 
YS-314]
 gi|259505978|ref|ZP_05748880.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
efficiens YS-314]
 gi|23494318|dbj|BAC19285.1| 5'-phosphoribosyl-5-aminoimidazole synthetase [Corynebacterium 
efficiens YS-314]
 gi|259166459|gb|EEW51013.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
efficiens YS-314]
Length=362

 Score =  509 bits (1310),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 252/365 (70%), Positives = 295/365 (81%), Gaps = 4/365 (1%)

Query  1    MTD-LAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLF  59
            M+D L  G G  P   G++YA+AGVDIEAGDRA++LF PLA +ATRPEVRG LGGFAGLF
Sbjct  1    MSDHLDTGNGATP--EGVSYAAAGVDIEAGDRAVELFAPLAKRATRPEVRGNLGGFAGLF  58

Query  60   TLRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYI  119
             L G YR+P+LAA SDGVGTKL +AQ MDKHDT+G+DLVAM VDDLV CGAEPLFL DYI
Sbjct  59   EL-GKYRKPILAAGSDGVGTKLVVAQMMDKHDTIGIDLVAMCVDDLVCCGAEPLFLQDYI  117

Query  120  AVGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNV  179
            A+G++VPE ++ IV+GIA+GC++AG ALLGGETAEHPG++EP HYD+SAT VGVVEAD++
Sbjct  118  AIGKVVPEHVAEIVSGIAEGCIQAGAALLGGETAEHPGVMEPGHYDVSATAVGVVEADDL  177

Query  180  LGPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTR  239
            LGP+RV+ GDVII M SSGLHSNGYSL R VL +   + +  H+EE GRTLGEELLEPTR
Sbjct  178  LGPERVRAGDVIIGMASSGLHSNGYSLARHVLFDTAGLTVDSHIEELGRTLGEELLEPTR  237

Query  240  IYAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRG  299
            IY+KDCLAL AE  V  FCHVTGGGLAGN+ RVIP GL+AE+ RGTWTP  +F  IA  G
Sbjct  238  IYSKDCLALIAECEVHVFCHVTGGGLAGNMSRVIPEGLVAEMSRGTWTPGQIFRSIASLG  297

Query  300  RVRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVG  359
            RV R EMEKTFNMGVGM+AVVA +D  RALA+LTARH+DCW LGTV  G    P   L G
Sbjct  298  RVPREEMEKTFNMGVGMVAVVAEKDRDRALAMLTARHIDCWELGTVRNGEDGEPNVILSG  357

Query  360  QHPRF  364
            +HP +
Sbjct  358  EHPGY  362


>gi|300790834|ref|YP_003771125.1| phosphoribosylformylglycinamidine cyclo-ligase [Amycolatopsis 
mediterranei U32]
 gi|299800348|gb|ADJ50723.1| phosphoribosylformylglycinamidine cyclo-ligase [Amycolatopsis 
mediterranei U32]
 gi|340532527|gb|AEK47732.1| phosphoribosylformylglycinamidine cyclo-ligase [Amycolatopsis 
mediterranei S699]
Length=356

 Score =  509 bits (1310),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 249/353 (71%), Positives = 298/353 (85%), Gaps = 2/353 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGD-YREPVLAA  72
            S   TYA+AGV I+AGD+A++L KP A +ATRPEV GG+GGFAGLF+L+ D ++EPVLA+
Sbjct  4    STSATYAAAGVSIDAGDKAVELLKPHAERATRPEVMGGVGGFAGLFSLKLDKWKEPVLAS  63

Query  73   SSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAI  132
            S+DGVGTK+A+AQA+DKHDTVG+DLVAMVVDDLVV GAEPLFL DYIAVG++ PE+++A+
Sbjct  64   STDGVGTKIAVAQALDKHDTVGIDLVAMVVDDLVVTGAEPLFLQDYIAVGKVHPEKIAAL  123

Query  133  VAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVII  192
            V GIA+GC+ AGCALLGGETAEHPGL+    YD+SATGVGVVEA  +L P++V+PGDV++
Sbjct  124  VGGIAEGCVLAGCALLGGETAEHPGLMGEHDYDMSATGVGVVEASQLLSPEKVRPGDVVL  183

Query  193  AMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAET  252
            A+GSSGLHSNGYSL R VLL+I RM L G+VEEF RTLGEE+LEPTRIYAKDCLALAAET
Sbjct  184  ALGSSGLHSNGYSLARHVLLDIARMPLGGYVEEFSRTLGEEMLEPTRIYAKDCLALAAET  243

Query  253  RVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNM  312
             VRTF H+TGGGL  NL RV+P GL+A +DRGTWTPAPVF +I QRG+V R+E+EKTFNM
Sbjct  244  EVRTFAHITGGGLEANLARVMPRGLVARLDRGTWTPAPVFAVIGQRGKVERSELEKTFNM  303

Query  313  GVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            GVGM+A+V  ED  RALA+LTARH+  WVLG V       GPRA L G HPRF
Sbjct  304  GVGMVAIVGAEDVDRALAMLTARHVPAWVLGDVQPAEDVDGPRAVLSGDHPRF  356


>gi|325001983|ref|ZP_08123095.1| phosphoribosylaminoimidazole synthetase [Pseudonocardia sp. P1]
Length=365

 Score =  506 bits (1304),  Expect = 2e-141, Method: Compositional matrix adjust.
 Identities = 253/366 (70%), Positives = 301/366 (83%), Gaps = 11/366 (3%)

Query  8    PGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLR-GDYR  66
            P  +PG+   +YASAGVDI+AG+RA++ F+P A KATRPEV GG+GGFAGLF  + G Y+
Sbjct  2    PSTEPGA--ASYASAGVDIDAGERAVEQFRPFAEKATRPEVMGGIGGFAGLFAAKFGKYQ  59

Query  67   EPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVP  126
            EPVLAAS+DGVGTK+AIAQAMDKHDT+G DLVAMVVDDLVVCGAEPLFL DYIAVG++VP
Sbjct  60   EPVLAASTDGVGTKVAIAQAMDKHDTIGQDLVAMVVDDLVVCGAEPLFLQDYIAVGKLVP  119

Query  127  ERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVK  186
            E+++ +V GIA+GC +AGCALLGGETAEHPGL+E   YD+SATGVG+V+A+ +L P+RV+
Sbjct  120  EQVATLVRGIAEGCQQAGCALLGGETAEHPGLMEEGGYDLSATGVGIVDAEKMLRPERVR  179

Query  187  PGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCL  246
            PGDV++AM SSGLHSNGYSL R VLL+I R+ L G +EEF  +LGEELL PTRIYAKDCL
Sbjct  180  PGDVLVAMASSGLHSNGYSLARHVLLDIARLPLEGELEEFDHSLGEELLVPTRIYAKDCL  239

Query  247  ALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEM  306
            A+ AET VRTF HVTGGGLA NL+RV+P GL A VDRG+WTPAPVF +I  RGRV R EM
Sbjct  240  AITAETGVRTFSHVTGGGLARNLERVLPDGLAATVDRGSWTPAPVFKLIQSRGRVDRDEM  299

Query  307  EKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCK--------GGKQGPRAKLV  358
            EKTFNMGVGM+AV+ PED  RALAVLTARH+  WVLG V +         G+ G R +L 
Sbjct  300  EKTFNMGVGMVAVLPPEDVDRALAVLTARHVPAWVLGEVGRTGDVEGAGSGELGARVQLR  359

Query  359  GQHPRF  364
            G+HPRF
Sbjct  360  GEHPRF  365


>gi|331694324|ref|YP_004330563.1| phosphoribosylformylglycinamidine cyclo-ligase [Pseudonocardia 
dioxanivorans CB1190]
 gi|326949013|gb|AEA22710.1| phosphoribosylformylglycinamidine cyclo-ligase [Pseudonocardia 
dioxanivorans CB1190]
Length=374

 Score =  505 bits (1301),  Expect = 4e-141, Method: Compositional matrix adjust.
 Identities = 251/353 (72%), Positives = 300/353 (85%), Gaps = 6/353 (1%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLR-GDYREPVLAASSDG  76
            +YASAGVDIEAG++A++  +P A  A+RPEV GG+GGFAGLF  + G Y EPVLAAS+DG
Sbjct  22   SYASAGVDIEAGEQAVEALRPHAELASRPEVLGGIGGFAGLFAPKLGRYAEPVLAASTDG  81

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTK+A+AQAMDKHDT+GLDLVAMVVDDLVVCGAEPLFL DYIAVG++VPE+++ IV GI
Sbjct  82   VGTKVAVAQAMDKHDTIGLDLVAMVVDDLVVCGAEPLFLQDYIAVGKLVPEQVATIVKGI  141

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            A+GC +AGCALLGGETAEHPGL+E   YD+SATGVG+V+A+ +L P+RV+PGDV++AMG+
Sbjct  142  AEGCKQAGCALLGGETAEHPGLMEAGGYDLSATGVGIVDAEAMLRPERVRPGDVLVAMGA  201

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            SGLHSNGYSL R VLL+I RM L GHVEEFG TLGEELL PTRIYA+DCLALAAET VRT
Sbjct  202  SGLHSNGYSLARHVLLDIARMPLEGHVEEFGTTLGEELLIPTRIYARDCLALAAETGVRT  261

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            F H+TGGGLA NL+RV+P GL+A  +RG+WTPAPVF +IA RGRV R EMEKTFNMGVGM
Sbjct  262  FAHITGGGLARNLERVLPDGLVAVAERGSWTPAPVFKLIAARGRVERAEMEKTFNMGVGM  321

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGP-----RAKLVGQHPRF  364
            +AV+ P+D  RALAVLTARH+  WVLG V +G  + P     R +L+G+HPRF
Sbjct  322  VAVLPPDDVDRALAVLTARHVPAWVLGEVRRGTGEEPKGVGSRVQLLGEHPRF  374


>gi|296141249|ref|YP_003648492.1| phosphoribosylformylglycinamidine cyclo-ligase [Tsukamurella 
paurometabola DSM 20162]
 gi|296029383|gb|ADG80153.1| phosphoribosylformylglycinamidine cyclo-ligase [Tsukamurella 
paurometabola DSM 20162]
Length=358

 Score =  498 bits (1283),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 261/364 (72%), Positives = 300/364 (83%), Gaps = 6/364 (1%)

Query  1    MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFT  60
            MTD    P      +G +YA+AGVDIEAGDRA++LFKP A +ATRPEV GGLGGFAGLF 
Sbjct  1    MTDSTNQP-----PQGASYAAAGVDIEAGDRAVELFKPHAKRATRPEVLGGLGGFAGLFA  55

Query  61   LRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIA  120
            L+  YREPVLAAS+DGVGTK+A+AQAM KHDTVG+DLVAMVVDDLVV GAEPLFL DYIA
Sbjct  56   LK-KYREPVLAASTDGVGTKIAVAQAMGKHDTVGIDLVAMVVDDLVVTGAEPLFLQDYIA  114

Query  121  VGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVL  180
            VG++VPE ++ +V GIA+GC+RAGCALLGGETAEHPGL+    YD+SATGVGVVEAD VL
Sbjct  115  VGKVVPETVAELVGGIAEGCVRAGCALLGGETAEHPGLMAEGEYDLSATGVGVVEADEVL  174

Query  181  GPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRI  240
            GPD V+ GDV+IAM SSGLHSNGYSL RKVLL+   M+L G+VEEFGRTLGEELLEPT I
Sbjct  175  GPDNVRAGDVVIAMKSSGLHSNGYSLARKVLLDWGHMDLGGYVEEFGRTLGEELLEPTAI  234

Query  241  YAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR  300
            YA DCL L  ET+VRTFCHVTGGGL  NL RVIP GL+A++DR TW+P+ VF +IAQRGR
Sbjct  235  YALDCLRLTQETQVRTFCHVTGGGLEANLARVIPDGLVADLDRNTWSPSAVFALIAQRGR  294

Query  301  VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQ  360
            V + EMEKTFNMGVGM+A+VAPED  RALAVLTARH+D WVLG++ K       A L G 
Sbjct  295  VEQAEMEKTFNMGVGMVAIVAPEDVDRALAVLTARHIDSWVLGSIKKSDGSSTGAVLSGS  354

Query  361  HPRF  364
            HP+F
Sbjct  355  HPKF  358


>gi|227547968|ref|ZP_03978017.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
lipophiloflavum DSM 44291]
 gi|227079979|gb|EEI17942.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
lipophiloflavum DSM 44291]
Length=359

 Score =  489 bits (1259),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 252/349 (73%), Positives = 293/349 (84%), Gaps = 2/349 (0%)

Query  17   ITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDG  76
            ++Y SAGV IEAGD+A++LF PLA +A+RPEVRGGLGGFAGLF L   YREP+LAA SDG
Sbjct  12   VSYESAGVSIEAGDKAVELFAPLAKRASRPEVRGGLGGFAGLFALG-KYREPLLAAGSDG  70

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTKLA+AQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIA+G++VPE+++ IV GI
Sbjct  71   VGTKLAVAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAIGKVVPEKVAQIVEGI  130

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            A+GC++AGCALLGGETAEHPG++ P+ YD+SAT VGVVEAD +LGPDRV  GDV+IAM S
Sbjct  131  AEGCVQAGCALLGGETAEHPGVMNPEDYDVSATAVGVVEADELLGPDRVHEGDVVIAMAS  190

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            SGLHSNGYSL R VLLE   + L GHVEE GRTLGEE+LEPTRIYA DCLALAAE  VRT
Sbjct  191  SGLHSNGYSLARHVLLERAGLPLDGHVEELGRTLGEEMLEPTRIYALDCLALAAECLVRT  250

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            FCHVTGGGL GN++R+IP G +AE++R TWTPAP+FT I   G V R EMEKTFNMGVGM
Sbjct  251  FCHVTGGGLVGNMERIIPEGKVAEMNRATWTPAPIFTFIQSVGDVAREEMEKTFNMGVGM  310

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK-QGPRAKLVGQHPRF  364
            +AVVAPED  RALA+L ARH+D WVLG V   G+ +  RA L G HP+F
Sbjct  311  VAVVAPEDRDRALAILAARHIDSWVLGEVRASGEGETARAVLSGNHPQF  359


>gi|311740214|ref|ZP_07714046.1| phosphoribosylaminoimidazole synthetase [Corynebacterium pseudogenitalium 
ATCC 33035]
 gi|311304769|gb|EFQ80840.1| phosphoribosylaminoimidazole synthetase [Corynebacterium pseudogenitalium 
ATCC 33035]
Length=350

 Score =  489 bits (1259),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 251/347 (73%), Positives = 290/347 (84%), Gaps = 1/347 (0%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            TYA+AGV IE GDRA++LF P A +ATRPEV GGLGGFAGLF L GDY+EP+LAA SDGV
Sbjct  5    TYAAAGVSIEEGDRAVELFAPHAKRATRPEVLGGLGGFAGLFKL-GDYKEPILAAGSDGV  63

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTKLA+AQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIAVG++VPE+++ +V GIA
Sbjct  64   GTKLAVAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAVGKVVPEKVAEVVKGIA  123

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            +GC++AG ALLGGETAEHPG++E + YD+SAT VGVVEAD VLGPD+V+ GDV+IAMGSS
Sbjct  124  EGCLQAGAALLGGETAEHPGMMEENEYDVSATAVGVVEADGVLGPDKVRDGDVLIAMGSS  183

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL R VLLE   M L GHVEE GR LGEELLEPTRIYAKDCLALA+E  V TF
Sbjct  184  GLHSNGYSLARHVLLEQAGMPLDGHVEELGRPLGEELLEPTRIYAKDCLALASECSVSTF  243

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
            CHVTGGGLAGNL+RVIP GL A+++R TWTP  +F +I+  G+V   EMEKTFNMGVGMI
Sbjct  244  CHVTGGGLAGNLERVIPEGLAADINRATWTPGQIFKLISSVGKVELAEMEKTFNMGVGMI  303

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            AVV PED  RALA+LTARH+D W LGTV     + PR  + G+HP F
Sbjct  304  AVVNPEDRDRALAMLTARHIDAWELGTVRSASGEEPRVVMHGEHPNF  350


>gi|255325913|ref|ZP_05367005.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
tuberculostearicum SK141]
 gi|255297125|gb|EET76450.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
tuberculostearicum SK141]
Length=350

 Score =  487 bits (1254),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 251/347 (73%), Positives = 290/347 (84%), Gaps = 1/347 (0%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            TYA+AGV IE GDRA++LF P A +ATRPEV GGLGGFAGLF L GDY+EP+LAA SDGV
Sbjct  5    TYAAAGVSIEEGDRAVELFAPHAKRATRPEVLGGLGGFAGLFKL-GDYKEPILAAGSDGV  63

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTKLA+AQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIAVG++VPE+++ +V GIA
Sbjct  64   GTKLAVAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAVGKVVPEKVAEVVKGIA  123

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            +GC++AG ALLGGETAEHPG++E + YD+SAT VGVVEAD VLGPD+V+ GDV+IAMGSS
Sbjct  124  EGCVQAGAALLGGETAEHPGMMEENEYDVSATAVGVVEADGVLGPDKVREGDVLIAMGSS  183

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL R VLLE   M L GHVEE GR LGEELLEPTRIYAKDCLALA+E  V TF
Sbjct  184  GLHSNGYSLARHVLLEQAGMPLDGHVEELGRPLGEELLEPTRIYAKDCLALASECSVSTF  243

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
            CHVTGGGLAGNL+RVIP GL A+++R TWTP  +F +I+  G+V   EMEKTFNMGVGMI
Sbjct  244  CHVTGGGLAGNLERVIPEGLAADINRATWTPGQIFKLISSVGKVDLAEMEKTFNMGVGMI  303

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            AVV PED  RALA+LTARH+D W LGTV     + PR  + G+HP F
Sbjct  304  AVVNPEDRDRALAMLTARHIDAWELGTVRSATGEEPRVVMHGEHPNF  350


>gi|38234486|ref|NP_940253.1| phosphoribosylaminoimidazole synthetase [Corynebacterium diphtheriae 
NCTC 13129]
 gi|38200749|emb|CAE50452.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
diphtheriae]
Length=354

 Score =  486 bits (1251),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 251/351 (72%), Positives = 291/351 (83%), Gaps = 1/351 (0%)

Query  14   SRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAAS  73
            +  ++YA+AGVDIEAGD+A++LF PLA KATRPEVRGGLGGFAGLF L   YR+P+LAA 
Sbjct  5    NDNVSYAAAGVDIEAGDKAVELFAPLAKKATRPEVRGGLGGFAGLFALG-KYRKPLLAAG  63

Query  74   SDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIV  133
            SDGVGTKLAIAQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIA+G++VPE ++ IV
Sbjct  64   SDGVGTKLAIAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAIGKVVPEHVAQIV  123

Query  134  AGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIA  193
            +GIA+GC++AGCALLGGETAEHPG++EP+HYD+SAT VGVVEAD VLGPDRV+ GDV+IA
Sbjct  124  SGIAEGCIQAGCALLGGETAEHPGVMEPEHYDVSATAVGVVEADEVLGPDRVRNGDVVIA  183

Query  194  MGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETR  253
            M SSGLHSNGYSL R VLL+   + L GH+EEF RTLGEELLEPT+IY KDCLALA E  
Sbjct  184  MASSGLHSNGYSLARHVLLDKAGLPLDGHMEEFDRTLGEELLEPTKIYTKDCLALADECE  243

Query  254  VRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMG  313
            V TFCHVTGGGLAGNL RVIP GL AE+ R TWTP  +F  I   G+V + EMEKTFNMG
Sbjct  244  VHTFCHVTGGGLAGNLARVIPEGLTAELSRATWTPGQIFRTIETIGQVPQVEMEKTFNMG  303

Query  314  VGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            VGM+AVVAP+D  RALA+LTARH+D W LGTV     + P   L G HP +
Sbjct  304  VGMVAVVAPKDRDRALAILTARHIDAWELGTVRATEGEEPSVILTGNHPGY  354


>gi|334697525|gb|AEG82322.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
ulcerans 809]
Length=354

 Score =  485 bits (1249),  Expect = 4e-135, Method: Compositional matrix adjust.
 Identities = 253/354 (72%), Positives = 291/354 (83%), Gaps = 2/354 (0%)

Query  11   DPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVL  70
            DP    ++YA+AGVDIEAGD+A++LF PLA KATRPEVRGGLGGFAGLF L   YREP+L
Sbjct  3    DP-KESVSYAAAGVDIEAGDKAVELFAPLAKKATRPEVRGGLGGFAGLFALG-KYREPLL  60

Query  71   AASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLS  130
            AA SDGVGTKLAIAQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIA+G++VPE ++
Sbjct  61   AAGSDGVGTKLAIAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAIGKVVPEHVA  120

Query  131  AIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDV  190
             IV+GIA+GC++AGCALLGGETAEHPG++EP HYD+SAT VGVVEAD +LGPDRV+ GD+
Sbjct  121  QIVSGIAEGCIQAGCALLGGETAEHPGVMEPGHYDVSATAVGVVEADELLGPDRVRNGDI  180

Query  191  IIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAA  250
            +IAM SSGLHSNGYSL R VLLE   + L GH+EE  RTLGEELLEPTRIY KDCLALA 
Sbjct  181  VIAMASSGLHSNGYSLARHVLLEKAGLPLDGHLEELDRTLGEELLEPTRIYTKDCLALAD  240

Query  251  ETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTF  310
            E  V TFCHVTGGGLAGNL RVIP GL AE+ R TWTPA +F +I   G+V + EMEKTF
Sbjct  241  ECEVHTFCHVTGGGLAGNLARVIPEGLTAELSRATWTPASIFRLIETVGQVPQEEMEKTF  300

Query  311  NMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            NMGVGM+AVVAP D  RALA+LTARH+D W LGTV    ++     L G HP +
Sbjct  301  NMGVGMVAVVAPRDRDRALAMLTARHIDAWELGTVRVSTEEEESVVLNGNHPSY  354


>gi|227506373|ref|ZP_03936422.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
striatum ATCC 6940]
 gi|227197024|gb|EEI77072.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
striatum ATCC 6940]
Length=350

 Score =  484 bits (1246),  Expect = 9e-135, Method: Compositional matrix adjust.
 Identities = 247/347 (72%), Positives = 289/347 (84%), Gaps = 1/347 (0%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGV  77
            TYA+AGV IE GDRA+ LF P A +A+RPEV GGLGGFAGLF L GDY+EPVLAA SDGV
Sbjct  5    TYAAAGVSIEEGDRAVTLFAPHAKRASRPEVMGGLGGFAGLFKL-GDYKEPVLAAGSDGV  63

Query  78   GTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIA  137
            GTKLA+AQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIAVG++VPE+++ IV GIA
Sbjct  64   GTKLAVAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAVGKVVPEKVAEIVKGIA  123

Query  138  DGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSS  197
            +GC++AG ALLGGETAEHPG+++P+ YD+SAT VGVVEAD++LGPD+V+ GDV+IAM SS
Sbjct  124  EGCVQAGAALLGGETAEHPGVMDPEEYDVSATAVGVVEADSILGPDKVRDGDVLIAMASS  183

Query  198  GLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTF  257
            GLHSNGYSL R VLLE   + L GH+EE GRTLGEELLEPTRIYAKDCLAL AE  V TF
Sbjct  184  GLHSNGYSLARYVLLEQAGLPLDGHIEELGRTLGEELLEPTRIYAKDCLALTAECNVSTF  243

Query  258  CHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMI  317
            CHVTGGGLAGNL+RVIP GL AEV+R TWTP  +F  I+  G+V   EMEKTFNMGVGMI
Sbjct  244  CHVTGGGLAGNLERVIPEGLTAEVNRSTWTPGQIFKTISSVGKVSLEEMEKTFNMGVGMI  303

Query  318  AVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            AVV+PED  RA+A++ ARH+D W LGT+   G+   R  + G+HP F
Sbjct  304  AVVSPEDRERAMAMMAARHVDAWELGTIRAAGEGEARVIMNGEHPNF  350


>gi|296395398|ref|YP_003660282.1| phosphoribosylformylglycinamidine cyclo-ligase [Segniliparus 
rotundus DSM 44985]
 gi|296182545|gb|ADG99451.1| phosphoribosylformylglycinamidine cyclo-ligase [Segniliparus 
rotundus DSM 44985]
Length=358

 Score =  483 bits (1244),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 247/348 (71%), Positives = 291/348 (84%), Gaps = 0/348 (0%)

Query  17   ITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDG  76
            ++YAS+GVDIEAG+RA+ LF P A KATRPEV GGLGGFAGLF L+  YREPVLAAS+DG
Sbjct  11   VSYASSGVDIEAGERAVSLFAPFAGKATRPEVLGGLGGFAGLFALKDGYREPVLAASTDG  70

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTK+ IA  +DK DTVGLDLVAMVVDDLVVCGAEPLFLLDYIA G++VPER++ +V+G+
Sbjct  71   VGTKVDIAAKLDKRDTVGLDLVAMVVDDLVVCGAEPLFLLDYIACGKLVPERVAELVSGV  130

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            A GC  AGCALLGGETAEHPGL+ PD +D+++T VGVVEAD+VLGPDRV+PGDV++AM S
Sbjct  131  AKGCELAGCALLGGETAEHPGLMHPDAFDLASTAVGVVEADSVLGPDRVRPGDVVVAMRS  190

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            SGLHSNGYSLVR VLLE   ++L GHV EFGRTLGEELLEPTRIY KDCLAL AET VRT
Sbjct  191  SGLHSNGYSLVRHVLLEQANLDLHGHVAEFGRTLGEELLEPTRIYVKDCLALIAETTVRT  250

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            FCHVTGGG+A NL+RVIP GL A +DR TWTP PVF +I   G+V+  E+EKTFN+GVGM
Sbjct  251  FCHVTGGGVAKNLERVIPEGLTAVLDRNTWTPGPVFDLIRTTGQVQLPELEKTFNLGVGM  310

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            +A++APED  RALAVLTARH+DCW++G +    +   +  L G HP F
Sbjct  311  LAILAPEDLDRALAVLTARHVDCWLVGDIRASSEDNGKVLLTGSHPGF  358


>gi|337291500|ref|YP_004630521.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
ulcerans BR-AD22]
 gi|334699806|gb|AEG84602.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
ulcerans BR-AD22]
Length=354

 Score =  483 bits (1243),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 253/354 (72%), Positives = 290/354 (82%), Gaps = 2/354 (0%)

Query  11   DPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVL  70
            DP    ++YA+AGVDIEAGD+A++LF PLA KATRPEVRGGLGGFAGLF L   YREP+L
Sbjct  3    DP-KESVSYAAAGVDIEAGDKAVELFAPLAKKATRPEVRGGLGGFAGLFALG-KYREPLL  60

Query  71   AASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLS  130
            AA SDGVGTKLAIAQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIA+G++VPE ++
Sbjct  61   AAGSDGVGTKLAIAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAIGKVVPEHVA  120

Query  131  AIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDV  190
             IV+GIA+GC++AGCALLGGETAEHPG++EP HYD+SAT VGVVEAD +LGPDRV+ GD+
Sbjct  121  QIVSGIAEGCIQAGCALLGGETAEHPGVMEPGHYDVSATAVGVVEADELLGPDRVRNGDI  180

Query  191  IIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAA  250
            +IAM SSGLHSNGYSL R VLLE   + L GH+EE  RTLGEELLEPTRIY KDCLALA 
Sbjct  181  VIAMASSGLHSNGYSLARHVLLEKAGLPLDGHLEELDRTLGEELLEPTRIYTKDCLALAD  240

Query  251  ETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTF  310
            E  V TFCHVTGGGLAGNL RVIP GL AE+ R TWTPA +F +I   G+V + EMEKTF
Sbjct  241  ECEVHTFCHVTGGGLAGNLARVIPEGLTAELSRATWTPASIFRLIETVGQVPQEEMEKTF  300

Query  311  NMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF  364
            NMGVGM+AVVAP D  RALA+LTARH+D W LGTV    +      L G HP +
Sbjct  301  NMGVGMVAVVAPRDRDRALAMLTARHIDAWELGTVRVSTEGEESVVLNGNHPSY  354


>gi|300859138|ref|YP_003784121.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
pseudotuberculosis FRC41]
 gi|300686592|gb|ADK29514.1| phosphoribosylformylglycinamidine cyclo-ligase [Corynebacterium 
pseudotuberculosis FRC41]
 gi|302206832|gb|ADL11174.1| Phosphoribosylaminoimidazole synthetase [Corynebacterium pseudotuberculosis 
C231]
 gi|302331394|gb|ADL21588.1| Phosphoribosylaminoimidazole synthetase [Corynebacterium pseudotuberculosis 
1002]
 gi|308277084|gb|ADO26983.1| Phosphoribosylaminoimidazole synthetase [Corynebacterium pseudotuberculosis 
I19]
 gi|341825526|gb|AEK93047.1| Phosphoribosylaminoimidazole synthetase [Corynebacterium pseudotuberculosis 
PAT10]
Length=353

 Score =  482 bits (1241),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 253/352 (72%), Positives = 290/352 (83%), Gaps = 2/352 (0%)

Query  11   DPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVL  70
            DP  R ++YA+AGVDIEAGD+A++LF PLA KATRPEVRGGLGGFAGLF L   YREP+L
Sbjct  3    DPKER-VSYAAAGVDIEAGDKAVELFAPLAKKATRPEVRGGLGGFAGLFALG-KYREPLL  60

Query  71   AASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLS  130
            AA SDGVGTKLAIAQAMDKHDT+G+DLVAM VDDLVVCGAEPLFL DYIA+G+++PE ++
Sbjct  61   AAGSDGVGTKLAIAQAMDKHDTIGIDLVAMCVDDLVVCGAEPLFLQDYIAIGKVIPEHVA  120

Query  131  AIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDV  190
             IVAGIA+GC++AGCALLGGETAEHPG++EP HYD+SAT VGVVEAD +LGPDRV+ GD+
Sbjct  121  QIVAGIAEGCIQAGCALLGGETAEHPGVMEPGHYDVSATAVGVVEADELLGPDRVRNGDI  180

Query  191  IIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAA  250
            +IAM SSGLHSNGYSL R VLLE   + L G+VEE  RTLGEELLEPTRIY KDCLALA 
Sbjct  181  VIAMASSGLHSNGYSLARHVLLEKAGLPLEGYVEELDRTLGEELLEPTRIYTKDCLALAD  240

Query  251  ETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTF  310
            E  V TFCHVTGGGLAGNL RVIP GL AE+ R  W+PAP+F +I   G+V + EMEKTF
Sbjct  241  ECEVHTFCHVTGGGLAGNLARVIPEGLTAELTRAYWSPAPIFRLIETVGQVPQEEMEKTF  300

Query  311  NMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHP  362
            NMGVGM+AVVAP D  RALA+LTARH+D W LGTV    +      L G HP
Sbjct  301  NMGVGMVAVVAPRDRDRALAMLTARHIDAWELGTVRVSAEGEESVVLNGNHP  352


>gi|257057726|ref|YP_003135558.1| phosphoribosylformylglycinamidine cyclo-ligase [Saccharomonospora 
viridis DSM 43017]
 gi|256587598|gb|ACU98731.1| phosphoribosylformylglycinamidine cyclo-ligase [Saccharomonospora 
viridis DSM 43017]
Length=356

 Score =  478 bits (1231),  Expect = 5e-133, Method: Compositional matrix adjust.
 Identities = 248/349 (72%), Positives = 294/349 (85%), Gaps = 2/349 (0%)

Query  18   TYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLR-GDYREPVLAASSDG  76
            TYA+AGVDI+AGD+A++L KP A++A RPEV GG+GGFAGLF L+ G + EP+LA+S+DG
Sbjct  8    TYAAAGVDIDAGDKAVELLKPHATRAARPEVVGGVGGFAGLFALKTGRWTEPLLASSTDG  67

Query  77   VGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGI  136
            VGTK AIAQA+DKHDTVG+DLVAMVV+DLVV GAEPLFL DYIAVG++VPE++ AIV+GI
Sbjct  68   VGTKTAIAQALDKHDTVGIDLVAMVVNDLVVTGAEPLFLQDYIAVGKVVPEKIEAIVSGI  127

Query  137  ADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGS  196
            A+GC+RAGCALLGGETAEHPG++    YD+SATGVGVVEA  VLGPD V+PGDV+I + S
Sbjct  128  AEGCVRAGCALLGGETAEHPGMMGEHDYDLSATGVGVVEASAVLGPDLVRPGDVVIGLRS  187

Query  197  SGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRT  256
            +GLHSNGYSL R VLL+I RM L GHVEEFGRTLGEELLEPTRIYAKDCLAL AE  VRT
Sbjct  188  TGLHSNGYSLARHVLLDIARMPLEGHVEEFGRTLGEELLEPTRIYAKDCLALIAEAEVRT  247

Query  257  FCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGM  316
            F H+TGGGL  NL+RV+PHG++A+++R TWTP PVF +IAQRGRV R EME+TFNMGVGM
Sbjct  248  FAHITGGGLQTNLERVLPHGVVAQLERHTWTPDPVFALIAQRGRVERAEMERTFNMGVGM  307

Query  317  IAVVAPEDTTRALAVLTARHLDCWVLGTV-CKGGKQGPRAKLVGQHPRF  364
            + VV+PED  RALA+LTARH+  WVLG V         R  L+G HPRF
Sbjct  308  VVVVSPEDVDRALAMLTARHVPAWVLGEVRASDDPDASRVSLIGDHPRF  356



Lambda     K      H
   0.321    0.140    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 685166507650




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40