BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0841
Length=80
Score E
Sequences producing significant alignments: (Bits) Value
gi|15840255|ref|NP_335292.1| hypothetical protein MT0863 [Mycoba... 152 2e-35
gi|31792029|ref|NP_854522.1| transmembrane protein [Mycobacteriu... 151 4e-35
gi|289573463|ref|ZP_06453690.1| conserved hypothetical protein [... 150 5e-35
gi|340625855|ref|YP_004744307.1| hypothetical protein MCAN_08431... 137 5e-31
gi|240170797|ref|ZP_04749456.1| integral membrane protein [Mycob... 93.6 9e-18
gi|183984753|ref|YP_001853044.1| integral membrane protein [Myco... 82.8 2e-14
gi|118616215|ref|YP_904547.1| integral membrane protein [Mycobac... 73.2 1e-11
gi|15840256|ref|NP_335293.1| hypothetical protein MT0864 [Mycoba... 67.0 9e-10
gi|306782120|ref|ZP_07420457.1| conserved membrane protein [Myco... 67.0 1e-09
gi|15607982|ref|NP_215357.1| integral membrane protein [Mycobact... 67.0 1e-09
gi|340625856|ref|YP_004744308.1| putative integral membrane prot... 66.6 1e-09
gi|289752896|ref|ZP_06512274.1| predicted protein [Mycobacterium... 66.2 1e-09
gi|240170796|ref|ZP_04749455.1| putative integral membrane prote... 60.8 6e-08
gi|290959946|ref|YP_003491128.1| protein [Streptomyces scabiei 8... 37.0 0.97
gi|289770214|ref|ZP_06529592.1| integral membrane transporter [S... 36.2 1.8
gi|21222604|ref|NP_628383.1| integral membrane transport protein... 36.2 1.8
gi|254387135|ref|ZP_05002406.1| integral membrane transport prot... 34.7 5.1
>gi|15840255|ref|NP_335292.1| hypothetical protein MT0863 [Mycobacterium tuberculosis CDC1551]
gi|57116790|ref|YP_177634.1| transmembrane protein [Mycobacterium tuberculosis H37Rv]
gi|148660618|ref|YP_001282141.1| putative transmembrane protein [Mycobacterium tuberculosis H37Ra]
39 more sequence titles
Length=80
Score = 152 bits (384), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 79/80 (99%), Positives = 80/80 (100%), Gaps = 0/80 (0%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
+VAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA
Sbjct 1 MVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
Query 61 LCLPLARALRRPTPSAMTTD 80
LCLPLARALRRPTPSAMTTD
Sbjct 61 LCLPLARALRRPTPSAMTTD 80
>gi|31792029|ref|NP_854522.1| transmembrane protein [Mycobacterium bovis AF2122/97]
gi|121636764|ref|YP_976987.1| putative transmembrane protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224989235|ref|YP_002643922.1| putative transmembrane protein [Mycobacterium bovis BCG str.
Tokyo 172]
gi|31617616|emb|CAD93726.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium bovis
AF2122/97]
gi|121492411|emb|CAL70879.1| Probable conserved transmembrane protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224772348|dbj|BAH25154.1| putative transmembrane protein [Mycobacterium bovis BCG str.
Tokyo 172]
gi|341600780|emb|CCC63451.1| probable conserved transmembrane protein [Mycobacterium bovis
BCG str. Moreau RDJ]
Length=80
Score = 151 bits (381), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 78/80 (98%), Positives = 79/80 (99%), Gaps = 0/80 (0%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
+VAASIVHHSAAPANRGRYHGIWSMTPV ASVVVPIMASYGPIHGAHLLAAVVVGSAGAA
Sbjct 1 MVAASIVHHSAAPANRGRYHGIWSMTPVFASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
Query 61 LCLPLARALRRPTPSAMTTD 80
LCLPLARALRRPTPSAMTTD
Sbjct 61 LCLPLARALRRPTPSAMTTD 80
>gi|289573463|ref|ZP_06453690.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
gi|339630906|ref|YP_004722548.1| hypothetical protein MAF_08500 [Mycobacterium africanum GM041182]
gi|289537894|gb|EFD42472.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
gi|339330262|emb|CCC25922.1| putative conserved transmembrane protein [Mycobacterium africanum
GM041182]
Length=80
Score = 150 bits (379), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 78/80 (98%), Positives = 80/80 (100%), Gaps = 0/80 (0%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
+VAASIV+HSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA
Sbjct 1 MVAASIVNHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
Query 61 LCLPLARALRRPTPSAMTTD 80
LCLPLARALRRPTPSAMTTD
Sbjct 61 LCLPLARALRRPTPSAMTTD 80
>gi|340625855|ref|YP_004744307.1| hypothetical protein MCAN_08431 [Mycobacterium canettii CIPT
140010059]
gi|340004045|emb|CCC43181.1| putative conserved transmembrane protein [Mycobacterium canettii
CIPT 140010059]
Length=76
Score = 137 bits (345), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 71/74 (96%), Positives = 72/74 (98%), Gaps = 0/74 (0%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAA 60
+VAASIVHHSAAPANRGRYHGIWSMTP VASVVVPIMASYGPIHG HLLAAVVVGSAGAA
Sbjct 1 MVAASIVHHSAAPANRGRYHGIWSMTPAVASVVVPIMASYGPIHGGHLLAAVVVGSAGAA 60
Query 61 LCLPLARALRRPTP 74
LCLPLARALRRPTP
Sbjct 61 LCLPLARALRRPTP 74
>gi|240170797|ref|ZP_04749456.1| integral membrane protein [Mycobacterium kansasii ATCC 12478]
Length=518
Score = 93.6 bits (231), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 51/74 (69%), Positives = 56/74 (76%), Gaps = 3/74 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVV---VGSA 57
V+AA IVH A PAN GRYHGIWSMT +ASVV PI+ASY +HG H L A+V VG
Sbjct 435 VIAAGIVHRIAPPANGGRYHGIWSMTLAIASVVAPIIASYSLVHGGHRLVAIVTVTVGLT 494
Query 58 GAALCLPLARALRR 71
GAALCLPLARALRR
Sbjct 495 GAALCLPLARALRR 508
>gi|183984753|ref|YP_001853044.1| integral membrane protein [Mycobacterium marinum M]
gi|183178079|gb|ACC43189.1| integral membrane protein [Mycobacterium marinum M]
Length=437
Score = 82.8 bits (203), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/74 (65%), Positives = 54/74 (73%), Gaps = 3/74 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVV---VGSA 57
V+AA IVH A PA+ GRYHGIWSMT +ASVV PI++S HG H L A+V VG A
Sbjct 346 VIAAGIVHRIAPPASGGRYHGIWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLA 405
Query 58 GAALCLPLARALRR 71
GAALCLPLARAL R
Sbjct 406 GAALCLPLARALNR 419
>gi|118616215|ref|YP_904547.1| integral membrane protein [Mycobacterium ulcerans Agy99]
gi|118568325|gb|ABL03076.1| integral membrane protein [Mycobacterium ulcerans Agy99]
Length=512
Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 42/71 (60%), Positives = 49/71 (70%), Gaps = 3/71 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVV---VGSA 57
V+A VH A PA+ GRYHGIWSMT +ASVV PI++S HG H L A+V VG A
Sbjct 425 VIAVGTVHRIAPPASGGRYHGIWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLA 484
Query 58 GAALCLPLARA 68
GAALCLPL R+
Sbjct 485 GAALCLPLNRS 495
>gi|15840256|ref|NP_335293.1| hypothetical protein MT0864 [Mycobacterium tuberculosis CDC1551]
gi|148822050|ref|YP_001286804.1| integral membrane protein [Mycobacterium tuberculosis F11]
gi|167967562|ref|ZP_02549839.1| conserved integral membrane protein [Mycobacterium tuberculosis
H37Ra]
38 more sequence titles
Length=442
Score = 67.0 bits (162), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 41/72 (57%), Positives = 48/72 (67%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAA---VVVGSA 57
VVAA IVH A PA+ GRYHGIWSM +SV PI+A++ +G L+ A V VG
Sbjct 352 VVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFF 411
Query 58 GAALCLPLARAL 69
GAALCLPLAR L
Sbjct 412 GAALCLPLARVL 423
>gi|306782120|ref|ZP_07420457.1| conserved membrane protein [Mycobacterium tuberculosis SUMu002]
gi|306787874|ref|ZP_07426196.1| conserved membrane protein [Mycobacterium tuberculosis SUMu004]
gi|306792215|ref|ZP_07430517.1| conserved membrane protein [Mycobacterium tuberculosis SUMu005]
gi|308325199|gb|EFP14050.1| conserved membrane protein [Mycobacterium tuberculosis SUMu002]
gi|308335473|gb|EFP24324.1| conserved membrane protein [Mycobacterium tuberculosis SUMu004]
gi|308339271|gb|EFP28122.1| conserved membrane protein [Mycobacterium tuberculosis SUMu005]
Length=442
Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/72 (57%), Positives = 48/72 (67%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAA---VVVGSA 57
VVAA IVH A PA+ GRYHGIWSM +SV PI+A++ +G L+ A V VG
Sbjct 352 VVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFF 411
Query 58 GAALCLPLARAL 69
GAALCLPLAR L
Sbjct 412 GAALCLPLARVL 423
>gi|15607982|ref|NP_215357.1| integral membrane protein [Mycobacterium tuberculosis H37Rv]
gi|31792030|ref|NP_854523.1| integral membrane protein [Mycobacterium bovis AF2122/97]
gi|121636765|ref|YP_976988.1| putative integral membrane protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
27 more sequence titles
Length=430
Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/72 (57%), Positives = 48/72 (67%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAA---VVVGSA 57
VVAA IVH A PA+ GRYHGIWSM +SV PI+A++ +G L+ A V VG
Sbjct 340 VVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFF 399
Query 58 GAALCLPLARAL 69
GAALCLPLAR L
Sbjct 400 GAALCLPLARVL 411
>gi|340625856|ref|YP_004744308.1| putative integral membrane protein [Mycobacterium canettii CIPT
140010059]
gi|340004046|emb|CCC43182.1| putative conserved integral membrane protein [Mycobacterium canettii
CIPT 140010059]
Length=430
Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/72 (57%), Positives = 48/72 (67%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAA---VVVGSA 57
VVAA IVH A PA+ GRYHGIWSM +SV PI+A++ +G L+ A V VG
Sbjct 340 VVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFF 399
Query 58 GAALCLPLARAL 69
GAALCLPLAR L
Sbjct 400 GAALCLPLARVL 411
>gi|289752896|ref|ZP_06512274.1| predicted protein [Mycobacterium tuberculosis EAS054]
gi|289693483|gb|EFD60912.1| predicted protein [Mycobacterium tuberculosis EAS054]
Length=422
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/72 (57%), Positives = 48/72 (67%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAA---VVVGSA 57
VVAA IVH A PA+ GRYHGIWSM +SV PI+A++ +G L+ A V VG
Sbjct 332 VVAAGIVHRIAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFF 391
Query 58 GAALCLPLARAL 69
GAALCLPLAR L
Sbjct 392 GAALCLPLARVL 403
>gi|240170796|ref|ZP_04749455.1| putative integral membrane protein [Mycobacterium kansasii ATCC
12478]
Length=428
Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 39/72 (55%), Positives = 44/72 (62%), Gaps = 3/72 (4%)
Query 1 VVAASIVHHSAAPANRGRYHGIWSMTPVVASVVVPIMASYGPIHGAHLL---AAVVVGSA 57
VV+A IVH PA+ GRY G+WSMT A+V PI+AS HG LL A V G
Sbjct 340 VVSAGIVHRITQPASSGRYQGVWSMTTAAAAVTAPILASCSLAHGGRLLMVGATVTAGLL 399
Query 58 GAALCLPLARAL 69
G ALC PLARAL
Sbjct 400 GTALCAPLARAL 411
>gi|290959946|ref|YP_003491128.1| protein [Streptomyces scabiei 87.22]
gi|260649472|emb|CBG72587.1| putative integral membrane protein [Streptomyces scabiei 87.22]
Length=442
Score = 37.0 bits (84), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 21/61 (35%), Positives = 36/61 (60%), Gaps = 1/61 (1%)
Query 18 RYHGIWSMTPVVASVVVPIMASYGPIHGAHLLAAVVVGSAGAALCLPLARALRRPTPSAM 77
R+ I+ + P ++ P +A +G + G L A+V++ +AG L + RA+R PTP A+
Sbjct 116 RFQRIFEVRPGYPVLLAPFVAVFGVVWGVWL-ASVLIAAAGGVLAFLVLRAVRAPTPVAL 174
Query 78 T 78
T
Sbjct 175 T 175
>gi|289770214|ref|ZP_06529592.1| integral membrane transporter [Streptomyces lividans TK24]
gi|289700413|gb|EFD67842.1| integral membrane transporter [Streptomyces lividans TK24]
Length=429
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 24/58 (42%), Positives = 34/58 (59%), Gaps = 3/58 (5%)
Query 15 NRGRYHGIWSMTPVVASVVVPIMASYGPIH-GAHLLAAV--VVGSAGAALCLPLARAL 69
RGRY G++SM+ VA++V P+M+ + H GA L + VVG+ AA L R L
Sbjct 344 GRGRYQGMYSMSWAVAALVAPLMSGFVIDHWGAEWLWGICAVVGTVAAAGYWGLMRGL 401
>gi|21222604|ref|NP_628383.1| integral membrane transport protein [Streptomyces coelicolor
A3(2)]
gi|9857165|emb|CAC04044.1| putative integral membrane transport protein [Streptomyces coelicolor
A3(2)]
Length=429
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 24/58 (42%), Positives = 34/58 (59%), Gaps = 3/58 (5%)
Query 15 NRGRYHGIWSMTPVVASVVVPIMASYGPIH-GAHLLAAV--VVGSAGAALCLPLARAL 69
RGRY G++SM+ VA++V P+M+ + H GA L + VVG+ AA L R L
Sbjct 344 GRGRYQGMYSMSWAVAALVAPLMSGFVIDHWGAEWLWGICAVVGTVAAAGYWGLMRGL 401
>gi|254387135|ref|ZP_05002406.1| integral membrane transport protein [Streptomyces sp. Mg1]
gi|194345951|gb|EDX26917.1| integral membrane transport protein [Streptomyces sp. Mg1]
Length=434
Score = 34.7 bits (78), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
Query 12 APAN-RGRYHGIWSMTPVVASVVVPIMASY 40
+PA+ RGRY G+++M+ VAS+V P+MA +
Sbjct 376 SPADGRGRYQGVYTMSWAVASLVAPLMAGF 405
Lambda K H
0.322 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 128850890930
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40