BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0845 Length=425 Score E Sequences producing significant alignments: (Bits) Value gi|15840259|ref|NP_335296.1| hypothetical protein MT0867 [Mycoba... 837 0.0 gi|15607985|ref|NP_215360.1| two component sensor kinase [Mycoba... 837 0.0 gi|298524338|ref|ZP_07011747.1| two component sensor kinase [Myc... 835 0.0 gi|31792033|ref|NP_854526.1| two component sensor kinase [Mycoba... 834 0.0 gi|289573467|ref|ZP_06453694.1| two component system sensor kina... 833 0.0 gi|289446410|ref|ZP_06436154.1| two component system sensor kina... 833 0.0 gi|326904935|gb|EGE51868.1| two component system sensor kinase [... 831 0.0 gi|289442254|ref|ZP_06431998.1| two component system sensor kina... 831 0.0 gi|308378733|ref|ZP_07483737.2| two component system sensor kina... 809 0.0 gi|289568807|ref|ZP_06449034.1| two component system sensor kina... 687 0.0 gi|240170793|ref|ZP_04749452.1| putative two component sensor ki... 634 1e-179 gi|118616213|ref|YP_904545.1| two component sensor kinase [Mycob... 584 1e-164 gi|254773765|ref|ZP_05215281.1| hypothetical protein MaviaA2_036... 577 1e-162 gi|183984749|ref|YP_001853040.1| two-component sensor kinase [My... 573 1e-161 gi|342860347|ref|ZP_08716998.1| two component sensor kinase [Myc... 572 6e-161 gi|41406788|ref|NP_959624.1| hypothetical protein MAP0690 [Mycob... 571 9e-161 gi|118467032|ref|YP_880141.1| hypothetical protein MAV_0874 [Myc... 570 2e-160 gi|240170795|ref|ZP_04749454.1| two-component sensor kinase [Myc... 561 5e-158 gi|254820485|ref|ZP_05225486.1| hypothetical protein MintA_11181... 554 1e-155 gi|296169486|ref|ZP_06851106.1| sensor histidine kinase [Mycobac... 551 6e-155 gi|336461178|gb|EGO40056.1| signal transduction histidine kinase... 546 3e-153 gi|183984751|ref|YP_001853042.1| two-component sensor kinase [My... 541 7e-152 gi|240172695|ref|ZP_04751354.1| putative two component sensor ki... 357 2e-96 gi|111022469|ref|YP_705441.1| sensor kinase, two-component syste... 164 2e-38 gi|226364987|ref|YP_002782770.1| two-component histidine kinase ... 159 1e-36 gi|118471818|ref|YP_884522.1| sensory histidine kinase [Mycobact... 153 5e-35 gi|331699430|ref|YP_004335669.1| histidine kinase [Pseudonocardi... 151 2e-34 gi|258650738|ref|YP_003199894.1| signal transduction histidine k... 150 3e-34 gi|315441792|ref|YP_004074671.1| signal transduction histidine k... 150 4e-34 gi|145221324|ref|YP_001132002.1| integral membrane sensor signal... 149 7e-34 gi|343926322|ref|ZP_08765831.1| putative two-component histidine... 149 7e-34 gi|229493754|ref|ZP_04387536.1| putative signal transduction his... 149 7e-34 gi|226307629|ref|YP_002767589.1| two-component histidine kinase ... 146 6e-33 gi|111017309|ref|YP_700281.1| signal transduction histidine kina... 144 4e-32 gi|333919978|ref|YP_004493559.1| sensor kinase, two-component sy... 141 2e-31 gi|226359826|ref|YP_002777604.1| two-component histidine kinase ... 140 5e-31 gi|169627166|ref|YP_001700815.1| two component sensor kinase [My... 116 7e-24 gi|284046826|ref|YP_003397166.1| integral membrane sensor signal... 105 2e-20 gi|302039256|ref|YP_003799578.1| putative histidine kinase [Cand... 97.1 6e-18 gi|226314988|ref|YP_002774884.1| two-component sensor histidine ... 92.4 1e-16 gi|290893829|ref|ZP_06556808.1| conserved hypothetical protein [... 92.0 2e-16 gi|217964879|ref|YP_002350557.1| sensor protein LiaS [Listeria m... 92.0 2e-16 gi|46907253|ref|YP_013642.1| histidine kinase [Listeria monocyto... 92.0 2e-16 gi|16803061|ref|NP_464546.1| hypothetical protein lmo1021 [Liste... 92.0 2e-16 gi|313609538|gb|EFR85083.1| sensor protein LiaS [Listeria monocy... 91.7 2e-16 gi|261821061|ref|YP_003259167.1| integral membrane sensor signal... 91.3 3e-16 gi|299822490|ref|ZP_07054376.1| sensor histidine kinase [Listeri... 91.3 3e-16 gi|116872423|ref|YP_849204.1| two-component sensor histidine kin... 90.5 5e-16 gi|310659233|ref|YP_003936954.1| two-component sensor histidine ... 89.7 8e-16 gi|313638501|gb|EFS03672.1| sensor protein LiaS [Listeria seelig... 89.7 8e-16 >gi|15840259|ref|NP_335296.1| hypothetical protein MT0867 [Mycobacterium tuberculosis CDC1551] gi|13880418|gb|AAK45110.1| hypothetical protein MT0867 [Mycobacterium tuberculosis CDC1551] gi|323720708|gb|EGB29784.1| two component system sensor kinase [Mycobacterium tuberculosis CDC1551A] Length=429 Score = 837 bits (2161), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 5 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 64 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 65 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 124 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 125 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 184 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI Sbjct 185 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 244 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 245 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 304 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 305 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 364 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 365 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 424 Query 421 LPLKR 425 LPLKR Sbjct 425 LPLKR 429 >gi|15607985|ref|NP_215360.1| two component sensor kinase [Mycobacterium tuberculosis H37Rv] gi|148660622|ref|YP_001282145.1| putative two component sensor kinase [Mycobacterium tuberculosis H37Ra] gi|148822053|ref|YP_001286807.1| two component sensor kinase [Mycobacterium tuberculosis F11] 42 more sequence titles Length=425 Score = 837 bits (2161), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/425 (99%), Positives = 425/425 (100%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|298524338|ref|ZP_07011747.1| two component sensor kinase [Mycobacterium tuberculosis 94_M4241A] gi|298494132|gb|EFI29426.1| two component sensor kinase [Mycobacterium tuberculosis 94_M4241A] Length=429 Score = 835 bits (2156), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/425 (99%), Positives = 424/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 5 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 64 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 65 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 124 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 125 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 184 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 185 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 244 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 245 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 304 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 305 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 364 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 365 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 424 Query 421 LPLKR 425 LPLKR Sbjct 425 LPLKR 429 >gi|31792033|ref|NP_854526.1| two component sensor kinase [Mycobacterium bovis AF2122/97] gi|121636768|ref|YP_976991.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989239|ref|YP_002643926.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Tokyo 172] 18 more sequence titles Length=425 Score = 834 bits (2154), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/425 (99%), Positives = 424/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|289573467|ref|ZP_06453694.1| two component system sensor kinase [Mycobacterium tuberculosis K85] gi|289537898|gb|EFD42476.1| two component system sensor kinase [Mycobacterium tuberculosis K85] Length=425 Score = 833 bits (2151), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/425 (99%), Positives = 424/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRI+SVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRISSVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|289446410|ref|ZP_06436154.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] gi|289419368|gb|EFD16569.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] Length=425 Score = 833 bits (2151), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/425 (99%), Positives = 424/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR +LLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREDLLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|326904935|gb|EGE51868.1| two component system sensor kinase [Mycobacterium tuberculosis W-148] gi|339293859|gb|AEJ45970.1| two component system sensor kinase [Mycobacterium tuberculosis CCDC5079] Length=425 Score = 831 bits (2147), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/425 (99%), Positives = 423/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRA GW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRASGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|289442254|ref|ZP_06431998.1| two component system sensor kinase [Mycobacterium tuberculosis T46] gi|289415173|gb|EFD12413.1| two component system sensor kinase [Mycobacterium tuberculosis T46] Length=425 Score = 831 bits (2146), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/425 (99%), Positives = 423/425 (99%), Gaps = 0/425 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSM RLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMVRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 Query 421 LPLKR 425 LPLKR Sbjct 421 LPLKR 425 >gi|308378733|ref|ZP_07483737.2| two component system sensor kinase [Mycobacterium tuberculosis SUMu010] gi|308359365|gb|EFP48216.1| two component system sensor kinase [Mycobacterium tuberculosis SUMu010] Length=423 Score = 809 bits (2090), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/414 (99%), Positives = 414/414 (100%), Gaps = 0/414 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 +PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 1 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL Sbjct 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI Sbjct 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI Sbjct 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRG 414 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATP+G Sbjct 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPQG 414 >gi|289568807|ref|ZP_06449034.1| two component system sensor kinase [Mycobacterium tuberculosis T17] gi|289542561|gb|EFD46209.1| two component system sensor kinase [Mycobacterium tuberculosis T17] Length=423 Score = 687 bits (1773), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/355 (99%), Positives = 352/355 (99%), Gaps = 0/355 (0%) Query 1 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV Sbjct 5 VPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 64 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSM RLEPFAFTAVDVLIL Sbjct 65 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMVRLEPFAFTAVDVLIL 124 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW Sbjct 125 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 184 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALR ELLAQTMTASEVLQRRIAEAI Sbjct 185 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI 244 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Sbjct 245 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 304 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTAS 355 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATT S Sbjct 305 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTGS 359 >gi|240170793|ref|ZP_04749452.1| putative two component sensor kinase [Mycobacterium kansasii ATCC 12478] Length=455 Score = 634 bits (1634), Expect = 1e-179, Method: Compositional matrix adjust. Identities = 337/411 (82%), Positives = 360/411 (88%), Gaps = 0/411 (0%) Query 14 HEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVL 73 H+YGVLV TS AEL RVR HQLRSYRIASVLR+GVV LMVAAM+VGT+RSEW QQ L Sbjct 44 HDYGVLVVETSDAELKRVRKLHQLRSYRIASVLRVGVVVLMVAAMLVGTNRSEWLQQSAL 103 Query 74 IGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYP 133 I YA+AALWAL LAYS SRR LRRF M R EP AFTAVDV LTGFQLLSTDGIYP Sbjct 104 IVAYALAALWALALAYSPSRRVIVLRRFVRMARYEPVAFTAVDVFALTGFQLLSTDGIYP 163 Query 134 LLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFL 193 LLIM LLPVLVGLDVS+RRAAVVLA TLVGFA+AV+ DP M+ AIGWPE +FRF LYAFL Sbjct 164 LLIMTLLPVLVGLDVSSRRAAVVLAFTLVGFALAVVQDPAMVWAIGWPEAVFRFVLYAFL 223 Query 194 CATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQ 253 CATAL+VVRIEERH RS+AGLSALR ELLAQTMTASEVLQRRI+E+IHDGPLQDVLAARQ Sbjct 224 CATALIVVRIEERHARSIAGLSALREELLAQTMTASEVLQRRISESIHDGPLQDVLAARQ 283 Query 254 ELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQR 313 ELIEL P DERV RALAGLQSASERLRQATFELHPAVLEQVGLG AV+QLAASTAQR Sbjct 284 ELIELQTAAPDDERVNRALAGLQSASERLRQATFELHPAVLEQVGLGAAVEQLAASTAQR 343 Query 314 SGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDG 373 SGIK+STDIDYP+R+ IDP++FGV RELLSNVVRHS A TASV LGITD CVLDVADDG Sbjct 344 SGIKVSTDIDYPVRNEIDPVMFGVARELLSNVVRHSRARTASVNLGITDGICVLDVADDG 403 Query 374 VGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 VG++GDTMARRLGEGHIGLASHRARVDAAGG VFL TP GTHVCVE+PLK Sbjct 404 VGISGDTMARRLGEGHIGLASHRARVDAAGGTFVFLDTPAGTHVCVEVPLK 454 >gi|118616213|ref|YP_904545.1| two component sensor kinase [Mycobacterium ulcerans Agy99] gi|118568323|gb|ABL03074.1| two component sensor kinase [Mycobacterium ulcerans Agy99] Length=464 Score = 584 bits (1505), Expect = 1e-164, Method: Compositional matrix adjust. Identities = 317/424 (75%), Positives = 347/424 (82%), Gaps = 1/424 (0%) Query 2 PSYGNLGRL-GGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV 60 PS N G+L G YGV V +TS AEL RVR HQLR+YRI SVLRIGVV MVAAM+V Sbjct 40 PSCANYGQLVGSCRLYGVPVVVTSDAELARVRRTHQLRAYRIGSVLRIGVVLFMVAAMLV 99 Query 61 GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL 120 GT R EW Q LI VYA AALWAL LA+ SR +L RF ++ R EP AFTAVDVL L Sbjct 100 GTPRREWGAQTALICVYAFAALWALALAFRRSRPMVSLDRFANIARYEPLAFTAVDVLAL 159 Query 121 TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW 180 TGFQLLSTDGIY LLIM LLPVLV LD+S+RRAAVVLA TLVGF +A+ DPV++R GW Sbjct 160 TGFQLLSTDGIYSLLIMTLLPVLVALDISSRRAAVVLALTLVGFGLALAQDPVVIRMNGW 219 Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 PE IFRF LYAFLCATALMVVR EERH RSVA LS +R ELLAQTMTASEVLQRRI+E+I Sbjct 220 PEAIFRFGLYAFLCATALMVVRSEERHARSVATLSVIREELLAQTMTASEVLQRRISESI 279 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG 300 HDGPLQDVLAARQELIEL A P D+RV ALAGLQSAS+ LRQATFELHPAVLEQVGLG Sbjct 280 HDGPLQDVLAARQELIELRAAAPHDQRVSTALAGLQSASDLLRQATFELHPAVLEQVGLG 339 Query 301 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI 360 AV+QLA+ AQRSGI+I+ D+DYPIR IDPIVFGV RELLSNVV+HS A ASV LGI Sbjct 340 AAVEQLASFHAQRSGIRITDDVDYPIRDEIDPIVFGVARELLSNVVQHSRARNASVALGI 399 Query 361 TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE 420 +D CVLDVADDGVGV+G+TMARRLG+GHIGLASHRARVDAAGG LVFL TP GTHVCV Sbjct 400 SDGVCVLDVADDGVGVSGETMARRLGQGHIGLASHRARVDAAGGSLVFLNTPTGTHVCVR 459 Query 421 LPLK 424 +PLK Sbjct 460 IPLK 463 >gi|254773765|ref|ZP_05215281.1| hypothetical protein MaviaA2_03692 [Mycobacterium avium subsp. avium ATCC 25291] Length=425 Score = 577 bits (1487), Expect = 1e-162, Method: Compositional matrix adjust. Identities = 295/414 (72%), Positives = 341/414 (83%), Gaps = 0/414 (0%) Query 12 GRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQI 71 G EYG VA+ AEL+RVR HQ+RSYRI SVLR+GVVGLMVAAM++GT+RSEWPQ+ Sbjct 12 GADEYGDRVAVAGDAELERVRAVHQMRSYRIGSVLRVGVVGLMVAAMIIGTARSEWPQES 71 Query 72 VLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGI 131 VLI +Y + AL A+ LA+++ RR+ + R +GRLEPFAFT VD++ LT FQLLST+GI Sbjct 72 VLILLYGIIALGAVALAFASFRRWIRIGRLAGVGRLEPFAFTVVDIMALTIFQLLSTNGI 131 Query 132 YPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYA 191 YPLLIM +LPVL+GLDVS+RRAAVVL +++GFA+AVL DPVM ++ PE FRF LY Sbjct 132 YPLLIMAMLPVLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMSSSVRLPEAGFRFLLYG 191 Query 192 FLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAA 251 FLC A +VVRIEERHTRSVAGLSALR ELLAQTM AS+V QRRI+E IHDGPLQD+LA Sbjct 192 FLCCAAFLVVRIEERHTRSVAGLSALREELLAQTMNASDVSQRRISEFIHDGPLQDILAV 251 Query 252 RQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTA 311 RQEL+ELDA P DER+GRALAGLQ ASERLRQATFELHPAVLEQVGLG AV+QLA TA Sbjct 252 RQELVELDAAVPDDERIGRALAGLQLASERLRQATFELHPAVLEQVGLGAAVQQLAEFTA 311 Query 312 QRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVAD 371 QRSGI+ISTDIDY RS ID +VFGVVRELLSNVV+HS A TA++ LG TD CVL V D Sbjct 312 QRSGIEISTDIDYSGRSAIDAVVFGVVRELLSNVVQHSRARTAAIMLGRTDGTCVLHVVD 371 Query 372 DGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLKR 425 DGVG +T+ARRLGEGHIGLASHRARV+AAGG LVFL P GTHVCVE+PL+ Sbjct 372 DGVGFNQETVARRLGEGHIGLASHRARVEAAGGELVFLDVPVGTHVCVEVPLRN 425 >gi|183984749|ref|YP_001853040.1| two-component sensor kinase [Mycobacterium marinum M] gi|183178075|gb|ACC43185.1| two-component sensor kinase [Mycobacterium marinum M] Length=405 Score = 573 bits (1478), Expect = 1e-161, Method: Compositional matrix adjust. Identities = 308/403 (77%), Positives = 337/403 (84%), Gaps = 0/403 (0%) Query 22 MTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAA 81 +TS AEL RVR HQLR+YRI SVLRIGVV MVAAM+VGT R EW Q LI VYA AA Sbjct 2 VTSDAELARVRRTHQLRAYRIGSVLRIGVVLFMVAAMLVGTPRREWGAQTALICVYAFAA 61 Query 82 LWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLP 141 LWAL LA+ SR +L RF ++ R EP AFTAVDVL LTGFQLLSTDGIY LLIM LLP Sbjct 62 LWALALAFRRSRPMVSLDRFANIARYEPLAFTAVDVLALTGFQLLSTDGIYSLLIMTLLP 121 Query 142 VLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVV 201 VLV LD+S+RRAAVVLA TLVGFA+A+ DPV++R GWPE IFRF LYAFLCATALMVV Sbjct 122 VLVALDISSRRAAVVLALTLVGFALALAQDPVVIRMNGWPEAIFRFGLYAFLCATALMVV 181 Query 202 RIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAV 261 R EERH RSVA LS +R ELLAQTMTASEVLQRRI+E+IHDGPLQDVLAARQELIEL A Sbjct 182 RSEERHARSVATLSVIREELLAQTMTASEVLQRRISESIHDGPLQDVLAARQELIELRAA 241 Query 262 TPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTD 321 P D+RV ALAGLQSAS+ LRQATFELHPAVLEQVGLG AV+QLA+ AQRSGI+I+ D Sbjct 242 APHDQRVSTALAGLQSASDLLRQATFELHPAVLEQVGLGAAVEQLASFHAQRSGIRITDD 301 Query 322 IDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTM 381 +DYPIR IDPIVFGV RELLSNVV+HS A ASV LGI+D CVLDVADDGVGV+G+TM Sbjct 302 VDYPIRDEIDPIVFGVARELLSNVVQHSRARNASVALGISDGVCVLDVADDGVGVSGETM 361 Query 382 ARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 ARRLG+GHIGLASHRARVDAAGG LVFL TP GTHVCV +PLK Sbjct 362 ARRLGQGHIGLASHRARVDAAGGSLVFLNTPTGTHVCVRIPLK 404 >gi|342860347|ref|ZP_08716998.1| two component sensor kinase [Mycobacterium colombiense CECT 3035] gi|342132002|gb|EGT85243.1| two component sensor kinase [Mycobacterium colombiense CECT 3035] Length=425 Score = 572 bits (1473), Expect = 6e-161, Method: Compositional matrix adjust. Identities = 294/410 (72%), Positives = 337/410 (83%), Gaps = 0/410 (0%) Query 15 EYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLI 74 EYG VA+T EL+RVR HQLRSYRI SVLRIGVVGLMVAAMV+GT RSEWPQQ VLI Sbjct 15 EYGDRVAVTGDVELERVRTVHQLRSYRIGSVLRIGVVGLMVAAMVIGTRRSEWPQQSVLI 74 Query 75 GVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPL 134 +YA+ AL AL LA++ RR+ + R ++GR EPF FT +D++ LT FQLLSTDG+YPL Sbjct 75 VLYALVALCALGLAFAPFRRWIGMGRLVAIGRWEPFVFTVIDIVALTVFQLLSTDGVYPL 134 Query 135 LIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLC 194 LIM +LPVL+GLDVS+RRAAVVL +++GFA+AVL DPVML + PE FRF LYAFLC Sbjct 135 LIMAMLPVLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMLSEVKLPEAGFRFLLYAFLC 194 Query 195 ATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQE 254 A +VVRIEERHTRSVAGLSALR ELLAQTM AS+ RRI+E IHDGPLQD+LA RQE Sbjct 195 CAAFLVVRIEERHTRSVAGLSALREELLAQTMNASDEAARRISEFIHDGPLQDILAVRQE 254 Query 255 LIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRS 314 L+EL + GDERV RALAGLQ ASERLRQATFELHPAVLEQVGLG AV+QLA TAQRS Sbjct 255 LVELGSALDGDERVDRALAGLQMASERLRQATFELHPAVLEQVGLGAAVQQLAELTAQRS 314 Query 315 GIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGV 374 GI I+TDI+Y RS IDP++FGVVRELLSNVV+H+GA +A+V LGITD CVL V DDGV Sbjct 315 GIDITTDIEYATRSDIDPVMFGVVRELLSNVVQHAGARSAAVMLGITDHTCVLHVVDDGV 374 Query 375 GVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 G +T+ARRLGEGHIGLASHRARV+AAGG L+FL P GTHVCVE+PLK Sbjct 375 GFGQETVARRLGEGHIGLASHRARVEAAGGALMFLDVPVGTHVCVEVPLK 424 >gi|41406788|ref|NP_959624.1| hypothetical protein MAP0690 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395138|gb|AAS03007.1| hypothetical protein MAP_0690 [Mycobacterium avium subsp. paratuberculosis K-10] Length=429 Score = 571 bits (1471), Expect = 9e-161, Method: Compositional matrix adjust. Identities = 294/414 (72%), Positives = 338/414 (82%), Gaps = 0/414 (0%) Query 12 GRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQI 71 G EYG VA+ AEL+RVR HQ+RSYRI SVLR+GVVGLMVAAM++GT+RSEWPQ+ Sbjct 16 GADEYGDRVAVAGDAELERVRAVHQMRSYRIGSVLRVGVVGLMVAAMIIGTARSEWPQES 75 Query 72 VLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGI 131 VLI +Y + AL A+ LA++ RR+ R +GRLEPFAFT VD+L LT FQLLST+GI Sbjct 76 VLILLYGIIALGAVALAFAPFRRWIGTGRLAGVGRLEPFAFTVVDILALTIFQLLSTNGI 135 Query 132 YPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYA 191 YPLLIM +LPVL+GLDVS+RRAAVVL +++GFA+AVL DPVM ++ PE FRF LY Sbjct 136 YPLLIMAMLPVLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMSSSVRLPEAGFRFLLYG 195 Query 192 FLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAA 251 FLC A +VVRIEERHTRSVAGLSALR ELLAQTM AS+V QRRI+E IHDGPLQD+LA Sbjct 196 FLCCAAFLVVRIEERHTRSVAGLSALREELLAQTMNASDVSQRRISEFIHDGPLQDILAV 255 Query 252 RQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTA 311 RQEL+ELDA P DE +GRALAGLQ ASERLRQATFELHPAVLEQVGLG AV+QLA TA Sbjct 256 RQELVELDAAVPDDEHIGRALAGLQLASERLRQATFELHPAVLEQVGLGAAVQQLAEFTA 315 Query 312 QRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVAD 371 QRSGI+ISTDIDY RS ID +VFGVVRELLS+VV+HS A TA++ LG TD CVL V D Sbjct 316 QRSGIEISTDIDYSGRSAIDAVVFGVVRELLSHVVQHSRARTAAIMLGRTDGTCVLHVVD 375 Query 372 DGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLKR 425 DGVG +T+ARRLGEGHIGLASHRARV+AAGG LVFL P GTHVCVE+PL+ Sbjct 376 DGVGFNQETVARRLGEGHIGLASHRARVEAAGGELVFLDVPVGTHVCVEVPLRN 429 >gi|118467032|ref|YP_880141.1| hypothetical protein MAV_0874 [Mycobacterium avium 104] gi|118168319|gb|ABK69216.1| conserved hypothetical protein [Mycobacterium avium 104] Length=406 Score = 570 bits (1469), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 291/406 (72%), Positives = 336/406 (83%), Gaps = 0/406 (0%) Query 20 VAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAV 79 +A+ AEL+RVR HQ+RSYRI SVLR+GVVGLMVAAM++GT+RSEWPQ+ VLI +Y + Sbjct 1 MAVAGDAELERVRAVHQMRSYRIGSVLRVGVVGLMVAAMIIGTARSEWPQESVLILLYGI 60 Query 80 AALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMIL 139 AL A+ LA++ RR+ + R +GRLEPFAFT VD+L LT FQLLST+GIYPLLIM + Sbjct 61 IALGAVALAFAPFRRWIGIGRLAGVGRLEPFAFTVVDILALTIFQLLSTNGIYPLLIMAM 120 Query 140 LPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALM 199 LPVL+GLDVS+RRAAVVL +++GFA+AVL DPVM ++ PE FRF LY FLC A + Sbjct 121 LPVLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMSSSVRLPEAGFRFLLYGFLCCAAFL 180 Query 200 VVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELD 259 VVRIEERHTRSVAGLSALR ELLAQTM AS+V QRRI+E IHDGPLQD+LA RQEL+ELD Sbjct 181 VVRIEERHTRSVAGLSALREELLAQTMNASDVSQRRISEFIHDGPLQDILAVRQELVELD 240 Query 260 AVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKIS 319 A P DER+GRALAGLQ ASERLRQATFELHPAVLEQVGLG AV+QLA TAQRSGI+IS Sbjct 241 AAVPDDERIGRALAGLQLASERLRQATFELHPAVLEQVGLGAAVQQLAEFTAQRSGIEIS 300 Query 320 TDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGD 379 TDIDY RS ID +VFGVVRELLSNVV+HS A TA++ LG TD CVL V DDGVG + Sbjct 301 TDIDYSGRSAIDAVVFGVVRELLSNVVQHSRARTAAIMLGRTDGTCVLHVVDDGVGFNQE 360 Query 380 TMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLKR 425 T+ARRLGEGHIGLASHRARV+AAGG LVFL P GTHVCVE+PL+ Sbjct 361 TVARRLGEGHIGLASHRARVEAAGGELVFLDVPVGTHVCVEVPLRN 406 >gi|240170795|ref|ZP_04749454.1| two-component sensor kinase [Mycobacterium kansasii ATCC 12478] Length=437 Score = 561 bits (1447), Expect = 5e-158, Method: Compositional matrix adjust. Identities = 299/412 (73%), Positives = 335/412 (82%), Gaps = 0/412 (0%) Query 13 RHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIV 72 R EYG+ VA+TS EL+RVR HQLRSYRI SVLRIGV+ ++AAM+VGT EW QQ V Sbjct 25 RREYGIPVAVTSDVELERVRKLHQLRSYRIVSVLRIGVLVFVIAAMIVGTPTHEWGQQTV 84 Query 73 LIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIY 132 L+ +Y VAAL AL LA+S +RR + R EP FTAVD++ LTGFQLLS G+Y Sbjct 85 LVALYGVAALCALALAFSPARRLLEAEESSGVRRWEPLVFTAVDIVALTGFQLLSAHGLY 144 Query 133 PLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAF 192 PLLIM LLPVL G+D+S+RRA VLA +L+GF +A + D V+L GWP T F F+LYAF Sbjct 145 PLLIMTLLPVLAGVDISSRRAVTVLAFSLLGFVLAGVHDGVLLGPTGWPHTAFLFSLYAF 204 Query 193 LCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAAR 252 LCATAL+VVRIEERH RSVAGLSALR ELLAQTMTASE LQRRI+E+IHDGPLQDVLAAR Sbjct 205 LCATALVVVRIEERHIRSVAGLSALREELLAQTMTASEELQRRISESIHDGPLQDVLAAR 264 Query 253 QELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQ 312 QEL+EL PGDERV RALAGLQ ASERLRQATFELHPAVLEQVGLG AV QLAASTAQ Sbjct 265 QELVELQIAWPGDERVDRALAGLQDASERLRQATFELHPAVLEQVGLGAAVLQLAASTAQ 324 Query 313 RSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADD 372 RSGI+ISTDIDYP+R+ IDPI+FGV RELLSNVVRHS A TASV LGI D CVLDVADD Sbjct 325 RSGIEISTDIDYPVRNEIDPIMFGVARELLSNVVRHSRARTASVNLGIADGTCVLDVADD 384 Query 373 GVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 GVG++GDTMARRLGEGHIGLASHR RVDAA G+ VFL T GTHV V +PLK Sbjct 385 GVGISGDTMARRLGEGHIGLASHRMRVDAARGIFVFLDTRAGTHVRVAVPLK 436 >gi|254820485|ref|ZP_05225486.1| hypothetical protein MintA_11181 [Mycobacterium intracellulare ATCC 13950] Length=425 Score = 554 bits (1427), Expect = 1e-155, Method: Compositional matrix adjust. Identities = 290/410 (71%), Positives = 330/410 (81%), Gaps = 0/410 (0%) Query 15 EYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLI 74 EYG VA AEL+RVR HQLRSYRI SVLRIGVVGLMVAAM++GT R EWPQ+ VLI Sbjct 15 EYGDRVAGAGDAELERVRTIHQLRSYRIGSVLRIGVVGLMVAAMIIGTDRHEWPQESVLI 74 Query 75 GVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPL 134 +YA A A LA++ RR+ + R ++GRLEPFAFT +D++ LT FQLLSTDG+YPL Sbjct 75 VLYACLAACAAALAFAPFRRWIGMGRLVAIGRLEPFAFTVIDIVALTVFQLLSTDGVYPL 134 Query 135 LIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLC 194 LIM +LPVL+GLDVS+RRAAVVL +++GFA+AVL DPVM A+ PE FRF LYAFLC Sbjct 135 LIMAMLPVLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMTSAVRLPEAGFRFLLYAFLC 194 Query 195 ATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQE 254 A +VVRIEERHTRSVAGLSALR ELLAQTMTAS+ RRI+E IHDGPLQD+LA RQE Sbjct 195 CAAFLVVRIEERHTRSVAGLSALREELLAQTMTASDEAARRISEFIHDGPLQDILAVRQE 254 Query 255 LIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRS 314 L ELD PGDER+ RA AGLQ ASERLRQATFELHPAVLEQVGLG AV+QLA TA+RS Sbjct 255 LDELDTAFPGDERIVRASAGLQQASERLRQATFELHPAVLEQVGLGAAVQQLAEFTAERS 314 Query 315 GIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGV 374 GI+I+TDIDY R+ IDP+VF +VRELLSNVVRHS A ASVRLGITD CVL V DDGV Sbjct 315 GIEIATDIDYSARNAIDPVVFAMVRELLSNVVRHSAARNASVRLGITDGTCVLHVVDDGV 374 Query 375 GVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 G + +T+ RLGEGHIGLASHRARV+AAGG VF P GTHVCVE+PLK Sbjct 375 GFSPETVTHRLGEGHIGLASHRARVEAAGGATVFFDVPVGTHVCVEVPLK 424 >gi|296169486|ref|ZP_06851106.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895752|gb|EFG75447.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=406 Score = 551 bits (1421), Expect = 6e-155, Method: Compositional matrix adjust. Identities = 278/406 (69%), Positives = 330/406 (82%), Gaps = 0/406 (0%) Query 20 VAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAV 79 +A+ S AEL RVR HQLRSYR+AS+LRIGVV LM+AAM+ T RSEWPQQ VLI YA+ Sbjct 1 MAVASDAELARVRRLHQLRSYRLASLLRIGVVALMIAAMLTDTRRSEWPQQSVLIVAYAM 60 Query 80 AALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMIL 139 A+ AL LA+S +RR+ R ++G LEPFAFT +DV++LT FQ+LST+G++PLLIM Sbjct 61 VAMCALALAFSRTRRWLGRGRLAAVGGLEPFAFTVIDVIVLTVFQVLSTNGLHPLLIMTA 120 Query 140 LPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALM 199 LP+L+GLDVS+RRAAVVL ++ GFA+AVL DP M+ IG E FRF LYAFLC TA + Sbjct 121 LPILIGLDVSSRRAAVVLIFSMAGFAIAVLEDPEMVGKIGATEATFRFLLYAFLCVTAFV 180 Query 200 VVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELD 259 VR+EERH RSVAGLSALR ELLAQTM AS+V QRRI+E+IHDGPLQD+LA RQEL+EL Sbjct 181 AVRVEERHARSVAGLSALREELLAQTMAASDVEQRRISESIHDGPLQDILAVRQELVELG 240 Query 260 AVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKIS 319 A P D+R+GRAL+GLQ+ASERLRQATFELHPAVLEQVGL AV+QLA A RSGI+I+ Sbjct 241 AALPDDDRIGRALSGLQTASERLRQATFELHPAVLEQVGLAAAVQQLATFAAPRSGIEIT 300 Query 320 TDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGD 379 TDIDYP R IDP+VFGVVRELLSNVV+HS A +AS+ LGITD CVL V DDGVG + Sbjct 301 TDIDYPTRGDIDPVVFGVVRELLSNVVQHSRARSASIMLGITDGTCVLHVVDDGVGFNDE 360 Query 380 TMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLKR 425 T+ARRLGEGHIGLASHR RV+AAGG LV L +P GTH+CVELP+ + Sbjct 361 TVARRLGEGHIGLASHRTRVEAAGGTLVMLDSPVGTHICVELPIAK 406 >gi|336461178|gb|EGO40056.1| signal transduction histidine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=389 Score = 546 bits (1406), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 280/389 (72%), Positives = 322/389 (83%), Gaps = 0/389 (0%) Query 37 LRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFF 96 +RSYRI SVLR+GVVGLMVAAM++GT+RSEWPQ+ VLI +Y + AL A+ LA++ RR+ Sbjct 1 MRSYRIGSVLRVGVVGLMVAAMIIGTARSEWPQESVLILLYGIIALGAVALAFAPFRRWI 60 Query 97 ALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVV 156 R +GRLEPFAFT VD+L LT FQLLST+GIYPLLIM +LPVL+GLDVS+RRAAVV Sbjct 61 GTGRLAGVGRLEPFAFTVVDILALTIFQLLSTNGIYPLLIMAMLPVLLGLDVSSRRAAVV 120 Query 157 LACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSA 216 L +++GFA+AVL DPVM ++ PE FRF LY FLC A +VVRIEERHTRSVAGLSA Sbjct 121 LIFSMLGFAIAVLQDPVMSSSVRLPEAGFRFLLYGFLCCAAFLVVRIEERHTRSVAGLSA 180 Query 217 LRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQ 276 LR ELLAQTM AS+V QRRI+E IHDGPLQD+LA RQEL+ELDA P DE +GRALAGLQ Sbjct 181 LREELLAQTMNASDVSQRRISEFIHDGPLQDILAVRQELVELDAAVPDDEHIGRALAGLQ 240 Query 277 SASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFG 336 ASERLRQATFELHPAVLEQVGLG AV+QLA TAQRSGI+ISTDIDY RS ID +VFG Sbjct 241 LASERLRQATFELHPAVLEQVGLGAAVQQLAEFTAQRSGIEISTDIDYSGRSAIDAVVFG 300 Query 337 VVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHR 396 VVRELLS+VV+HS A TA++ LG TD CVL V DDGVG +T+ARRLGEGHIGLASHR Sbjct 301 VVRELLSHVVQHSRARTAAIMLGRTDGTCVLHVVDDGVGFNQETVARRLGEGHIGLASHR 360 Query 397 ARVDAAGGVLVFLATPRGTHVCVELPLKR 425 ARV+AAGG LVFL P GTHVCVE+PL+ Sbjct 361 ARVEAAGGELVFLDVPVGTHVCVEVPLRN 389 >gi|183984751|ref|YP_001853042.1| two-component sensor kinase [Mycobacterium marinum M] gi|183178077|gb|ACC43187.1| two-component sensor kinase [Mycobacterium marinum M] Length=513 Score = 541 bits (1395), Expect = 7e-152, Method: Compositional matrix adjust. Identities = 290/412 (71%), Positives = 333/412 (81%), Gaps = 2/412 (0%) Query 13 RHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIV 72 R EYGV V MT EL+RV HQLRSYR+ SVLR+GV+ ++ AM++GT + EW QQI Sbjct 71 RCEYGVPVGMTGDFELERVHKLHQLRSYRLVSVLRLGVLVFLIGAMLIGTPQHEWAQQIT 130 Query 73 LIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIY 132 L+ VY +AA ALLLA+S R A ++ EP AFTAVD+ +LT FQLLS DGIY Sbjct 131 LVVVYVLAAAGALLLAFSPRR--VAASGAVTIRSWEPLAFTAVDIAVLTAFQLLSADGIY 188 Query 133 PLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAF 192 PLL+M LLP+LVG+DVS+RRA VVLA T+VGF +A + D V+L GWP+++F F+LYAF Sbjct 189 PLLMMTLLPILVGVDVSSRRAMVVLAFTIVGFTIAGVHDNVLLGDAGWPDSVFVFSLYAF 248 Query 193 LCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAAR 252 LCATAL+VVR EER RSVAGLSALR LLAQTMTASEVLQR I+E+IHDGPLQDVL AR Sbjct 249 LCATALVVVRTEERRVRSVAGLSALREALLAQTMTASEVLQRWISESIHDGPLQDVLVAR 308 Query 253 QELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQ 312 QEL+EL +V PGD+RV RALAGLQSASERLRQATFELHPAVLEQVGLG AV+QLA TA+ Sbjct 309 QELVELQSVWPGDDRVERALAGLQSASERLRQATFELHPAVLEQVGLGAAVEQLATFTAR 368 Query 313 RSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADD 372 RSGI++STD+DYPIR+ IDPI+FGV RELLSNVV H+ A SV LGITD CVLDVADD Sbjct 369 RSGIEVSTDVDYPIRNEIDPIMFGVARELLSNVVHHARAKHVSVSLGITDGACVLDVADD 428 Query 373 GVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLK 424 GVG+TG T ARRLGEGHIGLASHRARVDAAGG VFL P GTHVCVELPLK Sbjct 429 GVGITGGTAARRLGEGHIGLASHRARVDAAGGTFVFLDAPAGTHVCVELPLK 480 >gi|240172695|ref|ZP_04751354.1| putative two component sensor kinase [Mycobacterium kansasii ATCC 12478] Length=416 Score = 357 bits (916), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 200/402 (50%), Positives = 271/402 (68%), Gaps = 8/402 (1%) Query 24 SSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALW 83 ++ ++++V +LRS + S+LR+GV +M +AM T + P+Q VL+GVYAV + Sbjct 2 NNTDIEKVLRKQRLRSLQGGSILRVGVAVIMFSAMPSVTDPARLPEQAVLLGVYAVVTIG 61 Query 84 ALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVL 143 ALLL Y+ + + R L A T DV + GF+LLS G PLL+M LLP + Sbjct 62 ALLLTYAGTSQLLNDDR-----ALLTLALT--DVAAVFGFKLLSPGGFIPLLVMALLPRM 114 Query 144 VGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRI 203 V +++S RRA VVLAC F +VL DP+++R IG ET +Y F+C TAL+VV Sbjct 115 VAVELSLRRAGVVLACAFAVFTASVLQDPMIMRRIGPWETAVIVLVYGFICGTALLVVIF 174 Query 204 EERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTP 263 R+ +A L+ R LLA+TM AS+ +R+I+E IHDGPLQDVLAAR+++ +P Sbjct 175 RLRNIDELAELTTSREALLAETMNASQAERRQISEFIHDGPLQDVLAARRDIAGFLKRSP 234 Query 264 GDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDID 323 D + +ALA LQ AS LR+ATFELHPA+L+QVGL AV++L A TA RSG+ I+T+ID Sbjct 235 -DAPLEQALASLQDASRLLREATFELHPALLDQVGLAAAVEKLVAVTAARSGMAITTEID 293 Query 324 YPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMAR 383 YP + IDPI+FGV+REL+SNV RHS A++A+V+L + E +DVADDG+G+TGD AR Sbjct 294 YPEPNAIDPILFGVIRELVSNVARHSQASSATVKLTVDGEVARIDVADDGIGITGDVAAR 353 Query 384 RLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVELPLKR 425 RL +GHIGLASHRARV AAGG L L P G + VE+PL+R Sbjct 354 RLAQGHIGLASHRARVQAAGGTLTILEEPVGARLRVEVPLRR 395 >gi|111022469|ref|YP_705441.1| sensor kinase, two-component system [Rhodococcus jostii RHA1] gi|110821999|gb|ABG97283.1| sensor kinase, two-component system [Rhodococcus jostii RHA1] Length=394 Score = 164 bits (416), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 133/397 (34%), Positives = 206/397 (52%), Gaps = 27/397 (6%) Query 35 HQLRSYRIASVLRIGVVGLMVAAMVVGTSR-SEWPQQI---VLIGVYAVAALWALLLAYS 90 + + R+ ++LR+ ++GLM A++ R + W + +LIG AVA W + Sbjct 13 YSTEAVRVTAILRLPLIGLM--ALLGPVIRVTHWQPDVFAGLLIGYAAVALGWLI----- 65 Query 91 ASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLDVS 149 F L R +G + TA DV + ++S LL + LLP+ V Sbjct 66 -----FVL--VRDVGPWAGWVSTAADVTAVVALCVVSGGATSVLLPVFFLLPISVAFQYR 118 Query 150 TRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETI---FRFALYAFLCATALMVVRIEER 206 R A+V CT VG+ V + A+G+P+ + F F L+ TAL V + R Sbjct 119 PRLTAIVGVCTAVGYQVVWIVYSKRDDAVGFPDEVYLYFGFLLWLAAATTALSYVLV--R 176 Query 207 HTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDE 266 + +V L +R +L+A++M A E +R++AE +HDGPLQ+VLAAR ++ E P D Sbjct 177 RSATVISLMDVRRQLIAESMGAEERERRQLAEDLHDGPLQNVLAARLDVEEALERNPDDM 236 Query 267 RVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPI 326 V A + L+ + +LR LHP VL Q+GL A+++LA A+R G +++ +D Sbjct 237 LVA-AESALRETAAQLRSTVTTLHPQVLAQLGLTAALRELADLYARR-GFEMTVSVDDVG 294 Query 327 RSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLG 386 +++ V RELL+NV +H+ ATT + L + L VADDG G + R+ Sbjct 295 HPDCQELLYRVARELLTNVSKHARATTIELALTRAGGRTTLTVADDGAGFDPAVVPERVA 354 Query 387 EGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELP 422 +GHIGLASH RV++ GG ++P GT V V +P Sbjct 355 QGHIGLASHIVRVESLGGTFDVTSSPGSGTRVVVTVP 391 >gi|226364987|ref|YP_002782770.1| two-component histidine kinase [Rhodococcus opacus B4] gi|226243477|dbj|BAH53825.1| putative two-component histidine kinase [Rhodococcus opacus B4] Length=395 Score = 159 bits (401), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 123/387 (32%), Positives = 198/387 (52%), Gaps = 18/387 (4%) Query 41 RIASVLRIGVVGLMVAAMVVGTSRSEWPQQIV--LIGVYAVAALWALLLAYSASRRFFAL 98 R+ ++LR+ ++GLM A + S + W + L+ YA+ AL L+ F L Sbjct 19 RVTAILRLPLIGLM-ALLGPVISVTHWQSDVFAGLLSGYALIALGWLI---------FVL 68 Query 99 RRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLDVSTRRAAVVL 157 R +G + TA DV + ++S LL + LLP+ V + A+V Sbjct 69 --VRDVGPWAGWVSTAADVSAVLALCVVSGGATSVLLPVFFLLPISVAFQYRPKLTAIVG 126 Query 158 ACTLVGFAVAVLGDPVMLRAIGWPETIF-RFALYAFLCATALMVVRIEERHTRSVAGLSA 216 CT VG+ V + +G+P+ ++ F +L A + + R + +V L Sbjct 127 VCTAVGYQVVWIVYSKRDDLVGFPDEVYLYFGFLLWLAAATTALSYVLMRRSATVISLMD 186 Query 217 LRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQ 276 +R +L+A++M A E +R++AE +HDGPLQ+VLAAR ++ E P D + A + L+ Sbjct 187 VRRQLVAESMGAEERERRQLAEHLHDGPLQNVLAARLDVEEARERHP-DALLDAAESALR 245 Query 277 SASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFG 336 + +LR LHP VL Q+GL A+++LA +R +++S +D +++ Sbjct 246 ETAAQLRSTVTTLHPQVLAQLGLTAALRELADLFCRRGEMEMSVSLDDVGHPDCQELLYR 305 Query 337 VVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHR 396 V RELL+NV +H+ AT + L + L VADDG G + R+ +GHIGLASH Sbjct 306 VARELLTNVTKHARATKVELALSRAGGRITLTVADDGAGFDPAVVPERVAQGHIGLASHT 365 Query 397 ARVDAAGGVLVFLATP-RGTHVCVELP 422 RV++ GG ++P GT V V +P Sbjct 366 VRVESLGGTFDVTSSPGSGTRVVVTVP 392 >gi|118471818|ref|YP_884522.1| sensory histidine kinase [Mycobacterium smegmatis str. MC2 155] gi|118173105|gb|ABK74001.1| sensory histidine kinase [Mycobacterium smegmatis str. MC2 155] Length=388 Score = 153 bits (387), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 131/387 (34%), Positives = 195/387 (51%), Gaps = 20/387 (5%) Query 41 RIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR 100 R+++VLR+ ++GL+ ++V W L G+YAV +L Y+A+ + + Sbjct 16 RVSAVLRLPLIGLIFVLVMV------WEVDHWLPGLYAV-----ILGLYAAAAVLWLVVV 64 Query 101 FR-SMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLDVSTRRAAVVLA 158 R M R +A TAVD L+L +S LL + LLP+ V A++ Sbjct 65 IRGPMPRWAEWASTAVDGLVLLALCAVSGGATAALLPVFFLLPISVAFQDRPLLTAMLGT 124 Query 159 CTLVGFAVAVLGDPVMLRAIGWPETIFR---FALYAFLCATALMVVRIEERHTRSVAGLS 215 T G+ A + +G P ++ F L+ + TAL +V + R + V L Sbjct 125 ATATGYLGAWIFYSKRDDTVGLPNVVYMQVGFLLWLAVATTALSLVLV--RRSARVRALL 182 Query 216 ALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGL 275 +R L+ ++ A E+ +AEA+HDGPLQ +LAAR EL EL P D + A L Sbjct 183 DVRRRLVQESARADELRDAELAEALHDGPLQTLLAARLELDELRERNP-DPALDVVHAAL 241 Query 276 QSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVF 335 Q + LR LHP VL Q+GL PAV++L R + I +I + +++ Sbjct 242 QQTATGLRSTVTALHPQVLAQLGLAPAVRELLRQYENRGDLVIRANIADVGQPEAQALLY 301 Query 336 GVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASH 395 RELL+NV +H+ A T +VRL E+ VL V DDGVG D +A+ + EGHIGLAS Sbjct 302 RAARELLANVHKHARAATVTVRLFRQGERTVLTVVDDGVGFDPDIVAQSVAEGHIGLASL 361 Query 396 RARVDAAGGVLVFLATP-RGTHVCVEL 421 + R++A GG + + GT V V L Sbjct 362 QVRIEAMGGAMTISSEEGFGTQVTVIL 388 >gi|331699430|ref|YP_004335669.1| histidine kinase [Pseudonocardia dioxanivorans CB1190] gi|326954119|gb|AEA27816.1| histidine kinase [Pseudonocardia dioxanivorans CB1190] Length=407 Score = 151 bits (381), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 105/251 (42%), Positives = 144/251 (58%), Gaps = 12/251 (4%) Query 180 WPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEA 239 W + R A+ A + + + RI+ ++ L R +LL Q E +R ++E Sbjct 162 WASLLLRTAIVAGVGLGCIGLSRIQRSRVETIGSLVTDRTDLLGQLTGIEERERRVLSEH 221 Query 240 IHDGPLQDVLAARQELIELDAVTPGD----ERVGRALAGLQSASERLRQATFELHPAVLE 295 +HDG LQ VLAARQ+L DA GD +R+ AL L+S S LR ELHPAVL+ Sbjct 222 LHDGALQYVLAARQDLE--DARDTGDAGAFDRIEEAL--LES-SRLLRSTVSELHPAVLD 276 Query 296 QVGLGPAVKQLAASTAQRSGI--KISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATT 353 + GL A+ QL + A R+G ++STD R+ +D +++ REL+ NV H+ A++ Sbjct 277 RAGLTAALGQLVETAAARAGFAGEVSTDGWPAERTPLDGLLYRTARELVGNVAAHAKASS 336 Query 354 ASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFL-ATP 412 + LG D + L VADDGVG+ D MAR L GHIGLASHR R++AAGG A+P Sbjct 337 LRLTLGRVDGRARLVVADDGVGLPADAMARSLRRGHIGLASHRVRIEAAGGTFTAAPASP 396 Query 413 RGTHVCVELPL 423 GT V VELPL Sbjct 397 SGTVVTVELPL 407 >gi|258650738|ref|YP_003199894.1| signal transduction histidine kinase [Nakamurella multipartita DSM 44233] gi|258553963|gb|ACV76905.1| putative signal transduction histidine kinase [Nakamurella multipartita DSM 44233] Length=408 Score = 150 bits (380), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 101/252 (41%), Positives = 142/252 (57%), Gaps = 10/252 (3%) Query 181 PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAI 240 P + R A + A+ + RI+ S+ L R LL + MTA++ R +AE + Sbjct 154 PSIVLRVVALAGVGLAAVWLSRIQRSRVASIQALVDDRTRLLTELMTATDSAHRAMAENL 213 Query 241 HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSA----SERLRQATFELHPAVLEQ 296 HDG LQ VLAAR +L DA + R+ L A ++ LR ELHPAVLEQ Sbjct 214 HDGALQYVLAARMDL--EDARDGAPDEAARSFDRLDDALTQTAKLLRSTVSELHPAVLEQ 271 Query 297 VGLGPAVKQLAASTAQRSGIKISTD-IDYP--IRSGIDPIVFGVVRELLSNVVRHSGATT 353 GL AV QLA + A+R G+ +S + +P R+ D ++FGV REL+SNVVRH+ A+ Sbjct 272 SGLALAVGQLAGTAAERGGLTVSVESAGWPDEARTDQDQLLFGVARELISNVVRHAHASR 331 Query 354 ASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVL-VFLATP 412 ++ L + D L V+DDG+G T T AR+L EGHIG+ S R +V+AAGG V Sbjct 332 MAIGLELADGVAELTVSDDGIGFTPGTAARKLSEGHIGVDSQRVKVEAAGGRFSVDSPAA 391 Query 413 RGTHVCVELPLK 424 G V V++P++ Sbjct 392 GGATVRVQVPVR 403 >gi|315441792|ref|YP_004074671.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1] gi|315260095|gb|ADT96836.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1] Length=399 Score = 150 bits (379), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 124/388 (32%), Positives = 196/388 (51%), Gaps = 20/388 (5%) Query 41 RIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR 100 R+++VLR+ ++GL +A +V + W L G+YA A+L +Y+ + L Sbjct 21 RVSAVLRLPLIGL-IAVLVWIWEVNHW-----LPGLYA-----AILGSYAVVAVVWLLAV 69 Query 101 FR-SMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLDVSTRRAAVVLA 158 R + R +A +AVDVL++ ++S LL + LLP+ V A++ + Sbjct 70 SRGPVPRWADWASSAVDVLVIVSLCVVSGGATAALLPVFFLLPISVAFQDRPALTAIIGS 129 Query 159 CTLVGFAVAVLGDPVMLRAIGWPE---TIFRFALYAFLCATALMVVRIEERHTRSVAGLS 215 T V + + +G P T F F ++ + TAL V + R R + L Sbjct 130 VTAVAYLTVWVFYSRRDDEVGLPNMVYTQFGFLVWMAVATTALSFV-LAHRAVR-LRNLQ 187 Query 216 ALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGL 275 +R +L+++ M + E R +AE++HDGPLQ +LAAR EL E P D + A L Sbjct 188 EVRVQLVSEAMQSDERHNREVAESLHDGPLQTLLAARLELDEARERNP-DPALDAVYAAL 246 Query 276 QSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVF 335 Q ++ LR ELHP VL Q+GL +++L R +++ +++ +++ Sbjct 247 QETADGLRATVTELHPQVLAQLGLTAGIRELLRQFQSRHLLEVDAELEEVGEPQSQALLY 306 Query 336 GVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASH 395 RELL+N+V+H+ ATT VRL ++ VL VADDG G + LG+GHIGL S Sbjct 307 RAARELLTNIVKHADATTVRVRLARRSDRVVLSVADDGAGFDPAILGTSLGQGHIGLGSL 366 Query 396 RARVDAAGGVLVFLATP-RGTHVCVELP 422 AR DA GG + ++ +GT V P Sbjct 367 IARFDAMGGSMRITSSDGQGTEVTATSP 394 >gi|145221324|ref|YP_001132002.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK] gi|145213810|gb|ABP43214.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK] Length=398 Score = 149 bits (377), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 124/388 (32%), Positives = 196/388 (51%), Gaps = 20/388 (5%) Query 41 RIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR 100 R+++VLR+ ++GL +A +V + W L G+YA A+L +Y+ + L Sbjct 21 RVSAVLRLPLIGL-IAVLVWIWEVNHW-----LPGLYA-----AILGSYAVVAVVWLLAV 69 Query 101 FR-SMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLDVSTRRAAVVLA 158 R + R +A +AVDVL++ ++S LL + LLP+ V A++ + Sbjct 70 SRGPVPRWADWASSAVDVLVIVSLCVVSGGATAALLPVFFLLPISVAFQDRPALTAIIGS 129 Query 159 CTLVGFAVAVLGDPVMLRAIGWPE---TIFRFALYAFLCATALMVVRIEERHTRSVAGLS 215 T V + + +G P T F F ++ + TAL V + R R + L Sbjct 130 VTAVAYLTVWVFYSRRDDEVGLPNMVYTQFGFLVWMAVATTALSFV-LAHRAVR-LRNLQ 187 Query 216 ALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGL 275 +R +L+++ M + E R +AE++HDGPLQ +LAAR EL E P D + A L Sbjct 188 EVRVQLVSEAMQSDERHNREVAESLHDGPLQTLLAARLELDEARERNP-DPALDAVYAAL 246 Query 276 QSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVF 335 Q ++ LR ELHP VL Q+GL +++L R +++ +++ +++ Sbjct 247 QETADGLRATVTELHPQVLAQLGLTAGIRELLRQLQSRHLLEVDAELEEVGEPQSQALLY 306 Query 336 GVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASH 395 RELL+N+V+H+ ATT VRL ++ VL VADDG G + LG+GHIGL S Sbjct 307 RAARELLTNIVKHADATTVRVRLARRGDRVVLSVADDGAGFDPAILGTSLGQGHIGLGSL 366 Query 396 RARVDAAGGVLVFLATP-RGTHVCVELP 422 AR DA GG + ++ +GT V P Sbjct 367 IARFDAMGGSMRITSSDGQGTEVTATSP 394 >gi|343926322|ref|ZP_08765831.1| putative two-component histidine kinase [Gordonia alkanivorans NBRC 16433] gi|343763951|dbj|GAA12757.1| putative two-component histidine kinase [Gordonia alkanivorans NBRC 16433] Length=427 Score = 149 bits (377), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 115/304 (38%), Positives = 163/304 (54%), Gaps = 30/304 (9%) Query 139 LLPVLVGLDVSTRRAAVVLACTLVGFAVAVL------GDPVMLRAIGWPETIFRFALYAF 192 L+P++ + + R A+V+A T+V +AVA + G+P W + R + A Sbjct 134 LVPMIAAISLQPRLCAMVVASTVVVYAVANILARDSNGEP-------WSIIVLRILVVAA 186 Query 193 LCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAAR 252 L A+++ +++ ++ L+A RA LL TM E +R +A+ +HDG LQ VLAAR Sbjct 187 LAVGAVLLSQLQRSRVTTIGSLAAERARLLDATMEIEERERRDLADNLHDGALQYVLAAR 246 Query 253 QELIEL----DAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAA 308 QEL L D VT + R L+ ++ LR ELHPAVLEQ GL A+ LA+ Sbjct 247 QELATLRGSADPVT-----LDRVDGALRDSARLLRSTLSELHPAVLEQAGLAVALTDLAS 301 Query 309 STAQRSGI-KISTDI-DYP--IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEK 364 S R+G IS D +P +R+ D ++F RELL+NVV+H+ A TA V D Sbjct 302 SYGSRAGAPSISVDTAAWPTELRTTADSLLFAAARELLTNVVKHADAETAEVTAEFVDGV 361 Query 365 CVLDVADDGVGVTGDT---MARRLGEGHIGLASHRARVDAAGGVLVFLATPR-GTHVCVE 420 L V DDGVG++ + M RR GHIGLAS R R++ GG P GT V VE Sbjct 362 ARLVVVDDGVGLSNEVEELMRRRQAAGHIGLASRRVRIEGVGGTFSLENRPSGGTAVVVE 421 Query 421 LPLK 424 +P + Sbjct 422 VPAR 425 >gi|229493754|ref|ZP_04387536.1| putative signal transduction histidine kinase in 2 component regulatory system [Rhodococcus erythropolis SK121] gi|229319354|gb|EEN85193.1| putative signal transduction histidine kinase in 2 component regulatory system [Rhodococcus erythropolis SK121] Length=421 Score = 149 bits (377), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 106/293 (37%), Positives = 152/293 (52%), Gaps = 8/293 (2%) Query 137 MILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCAT 196 + ++PVL + T V+ACT+ F V+ + + WP + A + A Sbjct 123 LFVIPVLACTQLRTDVCVGVVACTIGVFFVSSWA-TMTSNSEPWPSILLSTMALAGVGAG 181 Query 197 ALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELI 256 A+ + RI+ ++ L R LLA+ M + + ++E +HDG LQ VLAAR +L Sbjct 182 AIGLTRIQRSRVLTIGQLVGHRTSLLAELMGLEQRERTELSEQLHDGALQYVLAARMDLD 241 Query 257 EL-DAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSG 315 EL D+ P + RA L A+ LR + ELHP VL VGL A+ LA S R G Sbjct 242 ELADSAEP--VALARAAKALGEATTLLRSSVSELHPTVLVHVGLARAIGDLARSAQGRGG 299 Query 316 IKISTDI---DYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADD 372 + + D + +R+ D ++FG RELL+NVV+H+GA + L D + VL V+DD Sbjct 300 VVVDVDTSGWNDDLRTSADDVLFGAARELLANVVKHAGAHNVRIELARLDHRAVLVVSDD 359 Query 373 GVGVTGDTMARRLGEGHIGLASHRARVDAAGGVL-VFLATPRGTHVCVELPLK 424 G G++ D +A R GHIGL SH RV AAGG V GT VE+P + Sbjct 360 GRGISADRIAERRAAGHIGLLSHELRVVAAGGSFSVGPGEESGTLARVEIPFQ 412 >gi|226307629|ref|YP_002767589.1| two-component histidine kinase [Rhodococcus erythropolis PR4] gi|226186746|dbj|BAH34850.1| putative two-component histidine kinase [Rhodococcus erythropolis PR4] Length=438 Score = 146 bits (369), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 105/292 (36%), Positives = 150/292 (52%), Gaps = 6/292 (2%) Query 137 MILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCAT 196 + ++PVL + T V+ACT +G A + + WP + A + A Sbjct 140 LFVIPVLACTQLRTDVCVGVVACT-IGVFFASSWATMTSNSEPWPSILLSTMALAGVGAG 198 Query 197 ALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELI 256 A+ + RI+ ++ L R LLA+ M + + ++E +HDG LQ VLAAR +L Sbjct 199 AIGLTRIQRSRVLTIGHLVGHRTSLLAELMGLEQRERTELSEQLHDGALQYVLAARMDLD 258 Query 257 ELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGI 316 EL A + + RA L A+ LR + ELHP VL VGL A+ LA S R G+ Sbjct 259 EL-AGSAEPVALARAGKALGEATTLLRSSVSELHPTVLVHVGLARAIGDLARSAQGRGGV 317 Query 317 KISTDI---DYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDG 373 + D + +R+ D ++FG RELL NVV+H+GA + L D + VL V+DDG Sbjct 318 VVDVDTSGWNDDLRTSADEVLFGATRELLGNVVKHAGAQNVRIELARLDHRAVLVVSDDG 377 Query 374 VGVTGDTMARRLGEGHIGLASHRARVDAAGGVL-VFLATPRGTHVCVELPLK 424 G++ D +A+R GHIGL SH RV AAGG V GT VE+P + Sbjct 378 RGISADRIAQRRAAGHIGLLSHELRVVAAGGSFSVGPGEESGTLARVEIPFE 429 >gi|111017309|ref|YP_700281.1| signal transduction histidine kinase in 2 component regulatory system [Rhodococcus jostii RHA1] gi|110816839|gb|ABG92123.1| probable signal transduction histidine kinase in 2 component regulatory system [Rhodococcus jostii RHA1] Length=425 Score = 144 bits (362), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 94/249 (38%), Positives = 133/249 (54%), Gaps = 5/249 (2%) Query 180 WPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEA 239 W + A L A A+M+ RI+ ++ L R LLA+ M + +R ++E Sbjct 165 WSSILLSTMALAVLGAGAVMLSRIQRSRVLTIGHLVRDRTALLAELMGLEQRERRALSEQ 224 Query 240 IHDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGL 299 +HDG LQ VLAA+ +L +L + E VGR L ++ LR ELHP VL++VGL Sbjct 225 LHDGALQFVLAAKMDLDDLTG-SADPEAVGRITHALTESATLLRATVSELHPTVLDRVGL 283 Query 300 GPAVKQLAASTAQRSGIKI---STDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASV 356 A+ L S R G ++ +++ +R+ D ++F RELLSNVV+H+ A T V Sbjct 284 ARALGDLTRSAQARGGFEVQLLTSEWVDDLRTSADDVLFSAARELLSNVVKHAQAGTVRV 343 Query 357 RLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPR-GT 415 L E VLDV DDG G++ + + R L GHIGL SH RV AAGG PR GT Sbjct 344 ELARWGEHAVLDVTDDGCGISREAIDRSLSRGHIGLTSHELRVVAAGGSFSVHPGPRSGT 403 Query 416 HVCVELPLK 424 +E+P + Sbjct 404 VAHIEMPFE 412 >gi|333919978|ref|YP_004493559.1| sensor kinase, two-component system [Amycolicicoccus subflavus DQS3-9A1] gi|333482199|gb|AEF40759.1| Sensor kinase, two-component system [Amycolicicoccus subflavus DQS3-9A1] Length=401 Score = 141 bits (356), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 87/242 (36%), Positives = 136/242 (57%), Gaps = 10/242 (4%) Query 185 FRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGP 244 F F L+ T L V + R + +VA L R +L+ Q+M E ++R+AEA+HDGP Sbjct 158 FGFLLWLAAATTGLSFVLV--RRSATVAALLETREQLVTQSMGTEERERQRLAEALHDGP 215 Query 245 LQDVLAAR---QELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGP 301 LQ++LAAR +E +E +A D V A + L+ + +LR LHP VL Q+GL Sbjct 216 LQNILAARMDLEEALEKNA----DPSVAAAESTLRETAAQLRSTVTSLHPQVLAQLGLTL 271 Query 302 AVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGIT 361 A+++LA A+R G ++ + R + +++ V RE L+N+ +H+ A V L T Sbjct 272 ALRELAEQYARRGGYELHMRLTEVSRPDCESLLYRVARESLANINKHAHARNVEVELSAT 331 Query 362 DEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVE 420 E+ L + DDGVG ++ R+ EGHIG+AS RV++ GG +++P GT + V Sbjct 332 AEEITLTITDDGVGFDPSVISHRVAEGHIGIASQYLRVESWGGNFDVVSSPGTGTRIVVR 391 Query 421 LP 422 +P Sbjct 392 IP 393 >gi|226359826|ref|YP_002777604.1| two-component histidine kinase [Rhodococcus opacus B4] gi|226238311|dbj|BAH48659.1| putative two-component histidine kinase [Rhodococcus opacus B4] Length=425 Score = 140 bits (352), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 94/251 (38%), Positives = 133/251 (53%), Gaps = 9/251 (3%) Query 180 WPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEA 239 W + A L A A+++ RI+ ++ L R LLA+ M + +R ++E Sbjct 165 WSSILLSTMALAILSAGAVVLSRIQRSRVLTIGHLVHDRTALLAELMGLEQRERRALSEQ 224 Query 240 IHDGPLQDVLAARQELIELDAVTPG--DERVGRALAGLQSASERLRQATFELHPAVLEQV 297 +HDG LQ VLAA+ ++LD +T G E V R L ++ LR ELHP VL++V Sbjct 225 LHDGALQFVLAAK---MDLDDLTGGADPEAVDRITHALTESATLLRATVSELHPTVLDRV 281 Query 298 GLGPAVKQLAASTAQRSGIKI---STDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTA 354 GL A+ + S R G + + + D +R+ D ++F RELLSNVV+H+ A T Sbjct 282 GLARALGDIVRSAQARGGFDVDLQTVEWDDDLRTSADDVLFSAARELLSNVVKHARARTV 341 Query 355 SVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPR- 413 V L T VLDV DDG G++ + + R L GHIGL SH RV AAGG PR Sbjct 342 RVELSRTGGHAVLDVTDDGCGISREAIDRSLSRGHIGLTSHELRVVAAGGSFSVRPGPRS 401 Query 414 GTHVCVELPLK 424 GT +E+P + Sbjct 402 GTVARIEMPFE 412 >gi|169627166|ref|YP_001700815.1| two component sensor kinase [Mycobacterium abscessus ATCC 19977] gi|169239133|emb|CAM60161.1| Possible two component sensor kinase [Mycobacterium abscessus] Length=395 Score = 116 bits (290), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 118/395 (30%), Positives = 192/395 (49%), Gaps = 34/395 (8%) Query 41 RIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR 100 R+++ LR+ ++GL+V ++G+ + Q+ GVY + +L AY+ S + Sbjct 17 RVSAWLRLPLIGLIV---LLGSDPN---IQMWHNGVY-----YGVLAAYTLSAVVWVGIA 65 Query 101 FRSMGRLEPF---AFTAVDVLILTGFQLLSTDGIYPLL-IMILLPVLVGLD---VSTRRA 153 R G++ + A T+ D+ + L S G LL + LLPV V T Sbjct 66 VR--GQVADWVAPAATSADIAAVVMLCLASGAGNTELLPVFFLLPVSVAFQERPAITAIL 123 Query 154 AVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRIEERHTRSVAG 213 ++ A G V + D + R G E + AL T M ++ R R V Sbjct 124 GIITAVAYFGILVYYIADGNLERIPG-DEYVTWAALLWLTVFTTGMCFVLKRRSAR-VVQ 181 Query 214 LSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAAR---QELIELDAVTPGDERVGR 270 L +R +L+ ++M A E R +AE +HDGPLQ++LAAR +E++E + D + Sbjct 182 LVHIREQLVLESMRADERRNREVAERLHDGPLQNLLAARLRIEEVLERQS----DPVLTA 237 Query 271 ALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDIDYPIRSGI 330 + L+ + LR A LHP VL ++GL A+++LA R + +ST ++ Sbjct 238 VHSSLRETAAELRGAVSSLHPQVLIELGLTAAIRELARQHTARGIVDVSTAVEEVGSPPA 297 Query 331 DPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLD--VADDGVGVTGDTMARRLGEG 388 P+V+ +ELL+N V+H A ++R+ ++ +C L V DDG G + + +G Sbjct 298 QPLVYRAAKELLTNAVKHGRAK--NIRVELSSRRCWLTLVVTDDGRGFDPRDLVLSVADG 355 Query 389 HIGLASHRARVDAAGGVLVFLATP-RGTHVCVELP 422 HIGLAS ++AAGG + + P GT V V P Sbjct 356 HIGLASLTVPIEAAGGAVTITSAPGAGTRVSVTAP 390 >gi|284046826|ref|YP_003397166.1| integral membrane sensor signal transduction histidine kinase [Conexibacter woesei DSM 14684] gi|283951047|gb|ADB53791.1| integral membrane sensor signal transduction histidine kinase [Conexibacter woesei DSM 14684] Length=398 Score = 105 bits (261), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 86/239 (36%), Positives = 125/239 (53%), Gaps = 9/239 (3%) Query 188 ALYA-FLCATALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQ 246 ALY ++ A+++ R+ R V LSA R L+AQ + A + +RR+A A+HD +Q Sbjct 152 ALYLLWMGVVAVLLSRLLVRRADEVERLSADRGRLVAQALDAEDRERRRLAGALHDEAVQ 211 Query 247 DVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQL 306 ++LAAR EL G + GL +LR A F+L+PA L+ GL A++ + Sbjct 212 NLLAARHELA-------GGGDLAFVQHGLDRTIAQLRDAVFDLYPATLDHAGLAAALEAV 264 Query 307 AASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCV 366 A +R+ D+D D +VF + RELL NV H+ A + +VR+ + Sbjct 265 AEHAGRRAHFSWQVDVDPDAIGLYDALVFSLARELLINVANHAEANSVAVRVRRLPGELQ 324 Query 367 LDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPLK 424 L+VADDG G+ + EGHIGLAS RV+A G L A P GT V LP++ Sbjct 325 LEVADDGRGLDPARLRSAPLEGHIGLASATERVEALDGRLEIAAQPGHGTLVRARLPVR 383 >gi|302039256|ref|YP_003799578.1| putative histidine kinase [Candidatus Nitrospira defluvii] gi|300607320|emb|CBK43653.1| putative Histidine kinase [Candidatus Nitrospira defluvii] Length=389 Score = 97.1 bits (240), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 80/238 (34%), Positives = 121/238 (51%), Gaps = 19/238 (7%) Query 196 TALMVVRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQEL 255 ++L V + E +H+R LRA L Q +TA E +RRIA +HD Q + +L Sbjct 155 SSLKVSQEELQHSRE-----ELRA-LAGQLLTAQEGERRRIARDLHDDVNQRLAMLAMDL 208 Query 256 IELDAVTPGD----ERVGRALAG-LQSASERLRQATFELHPAVLEQVGLGPAVKQLA--- 307 ++ GD E V R++ L + S+ +RQ + HP++L+ +GL AV++L Sbjct 209 RRIEKGEAGDLAAVEGVVRSITRRLTTVSDDVRQMAYRFHPSILDDLGLVKAVRRLVDDF 268 Query 308 ASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVL 367 ++T + + + D P+ + + V+ + +E L+NV RH+ AT V L DE L Sbjct 269 SATTKIEAVYVHHDAVSPVPTELATCVYRIAQESLNNVARHAQATEVEVELICDDEVITL 328 Query 368 DVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATP-RGTH--VCVELP 422 V D+GVG D+ G G +GL S + RV G L P RGTH VCV LP Sbjct 329 SVRDNGVGF--DSQQASQGLGRLGLLSMKERVRLVRGTLTVSTAPGRGTHLEVCVPLP 384 >gi|226314988|ref|YP_002774884.1| two-component sensor histidine kinase [Brevibacillus brevis NBRC 100599] gi|226097938|dbj|BAH46380.1| two-component sensor histidine kinase [Brevibacillus brevis NBRC 100599] Length=380 Score = 92.4 bits (228), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/227 (32%), Positives = 117/227 (52%), Gaps = 25/227 (11%) Query 215 SALRAELLA-QTMTASEVLQRRIAEAIHDGPLQDV--LAARQELIELDAVTPGDERVGRA 271 SA + +L+ + + A E ++R+A IHDGP Q + + R E++E +ER+ A Sbjct 161 SAKQHQLMGLKVIQAQEEERKRVAREIHDGPAQSMANVVLRSEIVER---MLKNERILEA 217 Query 272 LAGLQSASE--RL-----RQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTD--- 321 L E RL R+ F+L P L+ +GL P +++ + +R I+ S D Sbjct 218 QMELHELKEMVRLSLADVRRIIFDLRPMALDDLGLVPTLQKYIQTCEER--IQSSIDLVV 275 Query 322 --IDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGD 379 ++ P+RS + +F +V+E L+NV +H+GATT V+L + L V DDGVG Sbjct 276 FGVEPPLRSSVKAAIFRLVQECLNNVEKHAGATTVQVKLEFVQDSLSLVVKDDGVGF--- 332 Query 380 TMARRLGEGH-IGLASHRARVDAAGGVLVFLATP-RGTHVCVELPLK 424 + +R+ G+ GL R RV G + + P GT V ++P+K Sbjct 333 DLEKRMANGNSFGLLGMRERVQLLEGSVELQSAPGEGTKVIFQIPIK 379 >gi|290893829|ref|ZP_06556808.1| conserved hypothetical protein [Listeria monocytogenes FSL J2-071] gi|290556656|gb|EFD90191.1| conserved hypothetical protein [Listeria monocytogenes FSL J2-071] Length=352 Score = 92.0 bits (227), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 129 LASDRAESTGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 188 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIN 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 >gi|217964879|ref|YP_002350557.1| sensor protein LiaS [Listeria monocytogenes HCC23] gi|217334149|gb|ACK39943.1| sensor protein LiaS [Listeria monocytogenes HCC23] gi|307570562|emb|CAR83741.1| two-component histidine kinase, putative [Listeria monocytogenes L99] gi|336022926|gb|AEH92063.1| putative two-component sensor histidine kinase, LuxR family [Listeria monocytogenes M7] Length=352 Score = 92.0 bits (227), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 129 LASDRAESTGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 188 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIN 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 >gi|46907253|ref|YP_013642.1| histidine kinase [Listeria monocytogenes serotype 4b str. F2365] gi|47093967|ref|ZP_00231702.1| histidine kinase, putative [Listeria monocytogenes str. 4b H7858] gi|226223639|ref|YP_002757746.1| two-component sensor histidine kinase [Listeria monocytogenes Clip81459] 14 more sequence titles Length=352 Score = 92.0 bits (227), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 129 LASDRAESTGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 188 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIS 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 >gi|16803061|ref|NP_464546.1| hypothetical protein lmo1021 [Listeria monocytogenes EGD-e] gi|47096353|ref|ZP_00233949.1| histidine kinase, putative [Listeria monocytogenes str. 1/2a F6854] gi|224500733|ref|ZP_03669082.1| histidine kinase, putative [Listeria monocytogenes Finland 1988] 15 more sequence titles Length=352 Score = 92.0 bits (227), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 129 LASDRAESTGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 188 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIS 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 >gi|313609538|gb|EFR85083.1| sensor protein LiaS [Listeria monocytogenes FSL F2-208] Length=345 Score = 91.7 bits (226), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 122 LASDRAESTGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 181 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 182 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIN 241 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 242 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 298 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 299 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 336 >gi|261821061|ref|YP_003259167.1| integral membrane sensor signal transduction histidine kinase [Pectobacterium wasabiae WPP163] gi|261605074|gb|ACX87560.1| integral membrane sensor signal transduction histidine kinase [Pectobacterium wasabiae WPP163] Length=519 Score = 91.3 bits (225), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 76/217 (36%), Positives = 109/217 (51%), Gaps = 13/217 (5%) Query 218 RAELLAQTMTASEVLQRRIAEAIHDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQS 277 R L+ + + EV+++ IA +HD Q++ A + + + L + E A + Sbjct 300 RHRLMERIIHTEEVVRKDIARELHDDIGQNITAIQIQAM-LVKHSAPAEAAQHAAGQISE 358 Query 278 ASERL----RQATFELHPAVLEQVGLGPAVKQLAA--STAQRSGIKISTDIDYPIRSGID 331 S R+ RQ +L P VL+++ L A+ LA S A R GI+ D P D Sbjct 359 LSRRIHHTTRQLLRQLRPPVLDEMVLDKALNHLADEFSFATR-GIQFQLDYQLPTPPHDD 417 Query 332 PIVFGV---VRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEG 388 ++F + V+ELL+N+ +H+ AT +VRL D+ LDV DDGVG+ A G G Sbjct 418 VVIFTLYRLVQELLNNINKHASATQITVRLSQQDDLITLDVIDDGVGIAQKGNAHSTGGG 477 Query 389 HIGLASHRARVDAAGG-VLVFLATPRGTHVCVELPLK 424 GL RV A GG LV A PRGTH+ V LP K Sbjct 478 -FGLRGIEERVQALGGNWLVQPAAPRGTHIIVNLPTK 513 >gi|299822490|ref|ZP_07054376.1| sensor histidine kinase [Listeria grayi DSM 20601] gi|299816019|gb|EFI83257.1| sensor histidine kinase [Listeria grayi DSM 20601] Length=358 Score = 91.3 bits (225), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 71/214 (34%), Positives = 109/214 (51%), Gaps = 13/214 (6%) Query 219 AELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELDA-----VTPGDERVGRAL 272 AE Q+ A V +R RIA +HD Q + AA L L+ TP ++ + + Sbjct 134 AETAGQSKEAILVEERHRIARELHDSVSQQLFAAMMLLSALNEQGEKNATPAMQKQLKLV 193 Query 273 AGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYPIRSGI 330 + + S+ +R L P LE L ++QL + I++ +I D ++ GI Sbjct 194 ESIVNDSQSEMRALLLHLRPTQLEGKSLKVGMEQLLQELTAKIPIEVRWEIADIALKKGI 253 Query 331 DPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHI 390 + +F +V+ELLSN +RHS A VRL I D+ +L V DDGVG +A +G Sbjct 254 EDHLFRIVQELLSNTLRHSKAALLEVRLAIVDQVAILKVVDDGVGFNVGEVA----QGSY 309 Query 391 GLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 GL + R RV+ GG + ++ P +GT V V++PL Sbjct 310 GLQNMRERVEEFGGTIKIISFPNQGTSVEVKIPL 343 >gi|116872423|ref|YP_849204.1| two-component sensor histidine kinase, putative [Listeria welshimeri serovar 6b str. SLCC5334] gi|116741301|emb|CAK20423.1| two-component sensor histidine kinase, putative [Listeria welshimeri serovar 6b str. SLCC5334] Length=352 Score = 90.5 bits (223), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 72/219 (33%), Positives = 107/219 (49%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELDAVTPGD--ERVGR 270 L++ RAE QT A +R RIA +HD Q + AA L L+ + E + + Sbjct 129 LASERAESSGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATEAMQK 188 Query 271 ALAGLQS----ASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 L ++S + +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVEWQIEDIS 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDGVG D + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGVGFDMDNVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 >gi|310659233|ref|YP_003936954.1| two-component sensor histidine kinase [Clostridium sticklandii DSM 519] gi|308826011|emb|CBH22049.1| two-component sensor histidine kinase [Clostridium sticklandii] Length=392 Score = 89.7 bits (221), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 108/209 (52%), Gaps = 12/209 (5%) Query 224 QTMTASEVLQRRIAEAIHDGPLQDV--LAARQELIELDAVTPGDERVGRALAGLQSAS-- 279 + + A E +RRIA +HDGP Q++ L + E++E + G+ + L ++S Sbjct 172 KIIKAQEEERRRIARDVHDGPAQNIASLVIKTEIVE-KLLKRGNIHIEDELKDIKSQLRA 230 Query 280 --ERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI--DYPIRSGIDP-IV 334 + +R ++L P L++VGL P ++++AA + I I DYPI + ++ IV Sbjct 231 VLKEIRGIMYDLRPISLDEVGLIPTIERMAADMSYEKNIAIEVKNISDYPIINSLNKLIV 290 Query 335 FGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLAS 394 + +V+E L+N+++HSGA +R+ I V+DDG G ++ + GL+S Sbjct 291 YRIVQESLNNIIKHSGAKNVIIRMDIRKNSINGSVSDDGKGFNTESFT-EAKDKSFGLSS 349 Query 395 HRARVD-AAGGVLVFLATPRGTHVCVELP 422 + R + A G + + +GT V +P Sbjct 350 MKERAEIAHGSITIKSVVGKGTKVMFSIP 378 >gi|313638501|gb|EFS03672.1| sensor protein LiaS [Listeria seeligeri FSL S4-171] Length=352 Score = 89.7 bits (221), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 70/219 (32%), Positives = 109/219 (50%), Gaps = 13/219 (5%) Query 214 LSALRAELLAQTMTASEVLQR-RIAEAIHDGPLQDVLAARQELIELD-----AVTPGDER 267 L++ RAE QT A +R RIA +HD Q + AA L L+ + TP ++ Sbjct 129 LASERAESSGQTKEAILSEERHRIARELHDSVSQQLFAAMMLLSALNEQSEKSATPAMQK 188 Query 268 VGRALAGLQSASE-RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTDI-DYP 325 + + + + S+ +R L P LE L ++QL + I++ I D Sbjct 189 QLKMVESIVNESQSEMRALLLHLRPTQLEGKSLKTGIEQLLKELTTKLPIEVDWQIEDIS 248 Query 326 IRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRL 385 ++ GI+ +F +V+ELLSN +RHS A VRL D V+ V DDG+G + + Sbjct 249 LQKGIEDHLFRIVQELLSNTLRHSKAKLLEVRLVTMDNLAVMKVVDDGIGFDMENVR--- 305 Query 386 GEGHIGLASHRARVDAAGGVLVFLATP-RGTHVCVELPL 423 +G GL + R RV GG + ++ P RGT V +++PL Sbjct 306 -QGSYGLQNMRERVAEFGGTIKIISFPGRGTSVEIKIPL 343 Lambda K H 0.325 0.139 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 865206343656 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40