BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0848

Length=372
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|308231653|ref|ZP_07413309.2|  cysteine synthase A cysK2 [Mycob...   758    0.0   
gi|308370142|ref|ZP_07420451.2|  cysteine synthase A cysK2 [Mycob...   756    0.0   
gi|57116791|ref|YP_177762.1|  cysteine synthase A CysK2 [Mycobact...   754    0.0   
gi|121636771|ref|YP_976994.1|  putative cysteine synthase a cysK2...   753    0.0   
gi|340625862|ref|YP_004744314.1|  putative cysteine synthase A CY...   750    0.0   
gi|31792036|ref|NP_854529.1|  cysteine synthase A CysK2 [Mycobact...   750    0.0   
gi|183984736|ref|YP_001853027.1|  cysteine synthase a CysK2 [Myco...   632    3e-179
gi|240170780|ref|ZP_04749439.1|  cysteine synthase a CysK2 [Mycob...   625    3e-177
gi|339293862|gb|AEJ45973.1|  cysteine synthase A cysK2 [Mycobacte...   624    9e-177
gi|315441574|ref|YP_004074451.1|  cysteine synthase [Mycobacteriu...   546    3e-153
gi|126437127|ref|YP_001072818.1|  pyridoxal-5'-phosphate-dependen...   534    1e-149
gi|226349448|ref|YP_002776562.1|  putative cysteine synthase [Rho...   532    3e-149
gi|315446726|ref|YP_004079605.1|  cysteine synthase [Mycobacteriu...   531    6e-149
gi|54027728|ref|YP_121969.1|  putative pyridoxal-phosphate depend...   524    1e-146
gi|120406798|ref|YP_956627.1|  pyridoxal-5'-phosphate-dependent e...   522    4e-146
gi|54027672|ref|YP_121913.1|  putative pyridoxal-phosphate depend...   521    5e-146
gi|108801161|ref|YP_641358.1|  pyridoxal-5'-phosphate-dependent e...   518    8e-145
gi|108798415|ref|YP_638612.1|  pyridoxal-5'-phosphate-dependent e...   517    2e-144
gi|126436995|ref|YP_001072686.1|  pyridoxal-5'-phosphate-dependen...   516    2e-144
gi|169628366|ref|YP_001702015.1|  cysteine synthase A CysK2 [Myco...   498    6e-139
gi|169627555|ref|YP_001701204.1|  cysteine synthase [Mycobacteriu...   497    1e-138
gi|271966318|ref|YP_003340514.1|  cysteine synthase-like protein ...   494    8e-138
gi|302546893|ref|ZP_07299235.1|  pyridoxal-5-phosphate-dependent ...   492    4e-137
gi|343924998|ref|ZP_08764533.1|  putative cysteine synthase [Gord...   486    2e-135
gi|145221493|ref|YP_001132171.1|  pyridoxal-5'-phosphate-dependen...   486    3e-135
gi|262202520|ref|YP_003273728.1|  pyridoxal-5'-phosphate-dependen...   486    3e-135
gi|302538253|ref|ZP_07290595.1|  cysteine synthase B [Streptomyce...   484    7e-135
gi|54027707|ref|YP_121948.1|  putative pyridoxal-phosphate depend...   481    6e-134
gi|290963254|ref|YP_003494436.1|  cysteine synthase A [Streptomyc...   480    2e-133
gi|294813546|ref|ZP_06772189.1|  cysteine synthase a CysK2 [Strep...   473    2e-131
gi|329940468|ref|ZP_08289749.1|  cysteine synthase A [Streptomyce...   472    4e-131
gi|302555828|ref|ZP_07308170.1|  cysteine synthase B [Streptomyce...   471    7e-131
gi|297153713|gb|ADI03425.1|  cysteine synthase A [Streptomyces bi...   467    1e-129
gi|345009913|ref|YP_004812267.1|  pyridoxal-5'-phosphate-dependen...   462    4e-128
gi|134098308|ref|YP_001103969.1|  putative pyridoxal-phosphate de...   462    5e-128
gi|302547627|ref|ZP_07299969.1|  pyridoxal-5-phosphate-dependent ...   458    8e-127
gi|311893968|dbj|BAJ26376.1|  putative cysteine synthase [Kitasat...   457    1e-126
gi|297153541|gb|ADI03253.1|  cysteine synthase A [Streptomyces bi...   444    9e-123
gi|325003150|ref|ZP_08124262.1|  cysteine synthase A [Pseudonocar...   431    7e-119
gi|159040088|ref|YP_001539341.1|  pyridoxal-5'-phosphate-dependen...   428    7e-118
gi|291302174|ref|YP_003513452.1|  Pyridoxal-5'-phosphate-dependen...   427    2e-117
gi|145594839|ref|YP_001159136.1|  pyridoxal-5'-phosphate-dependen...   424    9e-117
gi|296165816|ref|ZP_06848316.1|  possible cysteine synthase a Cys...   365    6e-99 
gi|238059294|ref|ZP_04604003.1|  pyridoxal-phosphate dependent en...   361    9e-98 
gi|134102763|ref|YP_001108424.1|  putative pyridoxal-phosphate de...   361    1e-97 
gi|291005937|ref|ZP_06563910.1|  putative pyridoxal-phosphate dep...   360    2e-97 
gi|302538009|ref|ZP_07290351.1|  cysteine synthase B [Streptomyce...   349    5e-94 
gi|302540589|ref|ZP_07292931.1|  pyridoxal-5-phosphate-dependent ...   339    5e-91 
gi|323701021|gb|ADY00163.1|  hypothetical protein [Streptomyces a...   338    6e-91 
gi|290962492|ref|YP_003493674.1|  cysteine synthase [Streptomyces...   326    3e-87 


>gi|308231653|ref|ZP_07413309.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu001]
 gi|308378735|ref|ZP_07668815.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu010]
 gi|308379883|ref|ZP_07487977.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu011]
 gi|308397292|ref|ZP_07492479.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu012]
 gi|308216468|gb|EFO75867.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu001]
 gi|308359368|gb|EFP48219.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu010]
 gi|308363275|gb|EFP52126.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu011]
 gi|308366943|gb|EFP55794.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu012]
Length=404

 Score =  758 bits (1956),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 372/372 (100%), Positives = 372/372 (100%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  33   VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  92

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  93   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  152

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  153  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  212

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR
Sbjct  213  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  272

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  273  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  332

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  333  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  392

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  393  STTVIDPTQVVS  404


>gi|308370142|ref|ZP_07420451.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu002]
 gi|308370516|ref|ZP_07421838.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu003]
 gi|308371777|ref|ZP_07426202.2| cysteine synthase A cysK2 [Mycobacterium tuberculosis SUMu004]
 13 more sequence titles
 Length=404

 Score =  756 bits (1952),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 371/372 (99%), Positives = 371/372 (99%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  33   VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  92

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVEST GTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  93   PGGMKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLE  152

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  153  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  212

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR
Sbjct  213  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  272

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  273  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  332

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  333  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  392

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  393  STTVIDPTQVVS  404


>gi|57116791|ref|YP_177762.1| cysteine synthase A CysK2 [Mycobacterium tuberculosis H37Rv]
 gi|148660625|ref|YP_001282148.1| putative cysteine synthase A CysK2 [Mycobacterium tuberculosis 
H37Ra]
 gi|167967568|ref|ZP_02549845.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis H37Ra]
 gi|81415798|sp|Q79FV4.1|Y848_MYCTU RecName: Full=Uncharacterized pyridoxal phosphate-dependent protein 
CysK2
 gi|38490243|emb|CAE55331.1| POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) 
(O-ACETYLSERINE (THIOL)-LYASE) (CSASE) [Mycobacterium tuberculosis 
H37Rv]
 gi|148504777|gb|ABQ72586.1| putative cysteine synthase A CysK2 [Mycobacterium tuberculosis 
H37Ra]
Length=372

 Score =  754 bits (1948),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 371/372 (99%), Positives = 372/372 (100%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            +RSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  1    MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR
Sbjct  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  361  STTVIDPTQVVS  372


>gi|121636771|ref|YP_976994.1| putative cysteine synthase a cysK2 [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|148822056|ref|YP_001286810.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis F11]
 gi|224989242|ref|YP_002643929.1| putative cysteine synthase A [Mycobacterium bovis BCG str. Tokyo 
172]
 40 more sequence titles
 Length=372

 Score =  753 bits (1944),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 370/372 (99%), Positives = 371/372 (99%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            +RSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  1    MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVEST GTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLE  120

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR
Sbjct  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  361  STTVIDPTQVVS  372


>gi|340625862|ref|YP_004744314.1| putative cysteine synthase A CYSK2 [Mycobacterium canettii CIPT 
140010059]
 gi|340004052|emb|CCC43188.1| putative cysteine synthase A CYSK2 (O-acetylserine sulfhydrylase) 
(O-acetylserine (thiol)-lyase) (CSASE) [Mycobacterium canettii 
CIPT 140010059]
Length=372

 Score =  750 bits (1937),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 368/372 (99%), Positives = 370/372 (99%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            +RSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  1    MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVEST GTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLE  120

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDM+LIGVDTIGSTIFGQPASNR
Sbjct  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMQLIGVDTIGSTIFGQPASNR  240

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            R LPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  301  RKLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  361  STTVIDPTQVVS  372


>gi|31792036|ref|NP_854529.1| cysteine synthase A CysK2 [Mycobacterium bovis AF2122/97]
 gi|31617623|emb|CAD93733.1| POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) 
(O-ACETYLSERINE (THIOL)-LYASE) (CSASE) [Mycobacterium bovis 
AF2122/97]
Length=372

 Score =  750 bits (1936),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 369/372 (99%), Positives = 370/372 (99%), Gaps = 0/372 (0%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            +RSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN
Sbjct  1    MRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPALYMVECARARGDIAPGAAIVEST GTLGLGLALAGKVYRHPVTLVTDPGLE
Sbjct  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLE  120

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            PIIARMLTAYGAGVDM TQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR
Sbjct  121  PIIARMLTAYGAGVDMGTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
            SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR
Sbjct  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA
Sbjct  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR
Sbjct  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360

Query  361  STTVIDPTQVVS  372
            STTVIDPTQVVS
Sbjct  361  STTVIDPTQVVS  372


>gi|183984736|ref|YP_001853027.1| cysteine synthase a CysK2 [Mycobacterium marinum M]
 gi|183178062|gb|ACC43172.1| cysteine synthase a CysK2 [Mycobacterium marinum M]
Length=406

 Score =  632 bits (1630),  Expect = 3e-179, Method: Compositional matrix adjust.
 Identities = 312/376 (83%), Positives = 336/376 (90%), Gaps = 7/376 (1%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDP----DRGFWAKL  56
            +R RQTRDRYR++PEGY   PGRNRHPGTMVGNTPVLW+   SG + P    DRGFWAKL
Sbjct  34   MRPRQTRDRYRVVPEGYHPIPGRNRHPGTMVGNTPVLWV---SGDASPVGSADRGFWAKL  90

Query  57   EGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTD  116
            EGFNPGGMKDRPA++MVE ARARG++APGAAIVEST GTLGLGLALAG VY HPVTLVTD
Sbjct  91   EGFNPGGMKDRPAMHMVERARARGELAPGAAIVESTSGTLGLGLALAGSVYGHPVTLVTD  150

Query  117  PGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNV  176
            PGLEPIIARMLTAYGA VDMVT+PHPVGGWQQARKDRVAQL+A  P AWNP+QY NPDNV
Sbjct  151  PGLEPIIARMLTAYGARVDMVTEPHPVGGWQQARKDRVAQLLAADPSAWNPDQYSNPDNV  210

Query  177  GAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQP  236
             AYR LALE+ AQLGR+DVLVCSVGTGGHS+GVARVLREFNP MRLIGVDTIGSTIFGQP
Sbjct  211  DAYRPLALEMAAQLGRVDVLVCSVGTGGHSSGVARVLREFNPAMRLIGVDTIGSTIFGQP  270

Query  237  ASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVA  296
            AS+RLMRGLGSSI+PRNVDY AF+EVHWVAP EAVWACRS+AATHYASGGWSVGAVALVA
Sbjct  271  ASSRLMRGLGSSIFPRNVDYSAFNEVHWVAPAEAVWACRSMAATHYASGGWSVGAVALVA  330

Query  297  GWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVT  356
            GWAAR LP+D TIAAVFPDGPQRYFDT+YND YCNEH LLG +P TEP+ IASP  AVV 
Sbjct  331  GWAARTLPSDITIAAVFPDGPQRYFDTVYNDDYCNEHGLLGQRPATEPEVIASPSAAVVQ  390

Query  357  RWTRSTTVIDPTQVVS  372
            RWTRS TVIDPTQV +
Sbjct  391  RWTRSATVIDPTQVAA  406


>gi|240170780|ref|ZP_04749439.1| cysteine synthase a CysK2 [Mycobacterium kansasii ATCC 12478]
Length=400

 Score =  625 bits (1613),  Expect = 3e-177, Method: Compositional matrix adjust.
 Identities = 305/373 (82%), Positives = 334/373 (90%), Gaps = 7/373 (1%)

Query  4    RQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDP----DRGFWAKLEGF  59
            RQ RDRYR++P+ YQ+ P RNR PGTMVGNTPVLWI   SG++ P    DRGFWAKLEGF
Sbjct  31   RQNRDRYRVIPQAYQLPPSRNRQPGTMVGNTPVLWI---SGSAGPVGSADRGFWAKLEGF  87

Query  60   NPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGL  119
            NPGGMKDRPA++MVE AR RGD+APGAAI+EST GTLGLGLALAG  YRHPVTLVTDPGL
Sbjct  88   NPGGMKDRPAMHMVERARVRGDLAPGAAIIESTSGTLGLGLALAGNAYRHPVTLVTDPGL  147

Query  120  EPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAY  179
            EPIIARMLTAYG+ VDMVT+PHPVGGWQQARKDRVA+L+A  P AWNPNQY NPDNV AY
Sbjct  148  EPIIARMLTAYGSRVDMVTEPHPVGGWQQARKDRVAELLAADPAAWNPNQYSNPDNVDAY  207

Query  180  RSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASN  239
            R LALELVAQLG++DVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPA++
Sbjct  208  RPLALELVAQLGKVDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPATS  267

Query  240  RLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWA  299
            RLMRGLGSSIYPRNVDY AF+EVHWVAP EAVWACR+LAATHYASGGWSVGAV LVAGWA
Sbjct  268  RLMRGLGSSIYPRNVDYAAFNEVHWVAPAEAVWACRNLAATHYASGGWSVGAVGLVAGWA  327

Query  300  ARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWT  359
            AR LP+DTTIAAVFPDGP RYFDTIYND YC+EH LLG +P T+PDEIASP  AVVTRWT
Sbjct  328  ARTLPSDTTIAAVFPDGPNRYFDTIYNDEYCDEHGLLGDRPATDPDEIASPSAAVVTRWT  387

Query  360  RSTTVIDPTQVVS  372
            R+T V+DP++  +
Sbjct  388  RTTAVVDPSRAAA  400


>gi|339293862|gb|AEJ45973.1| cysteine synthase A cysK2 [Mycobacterium tuberculosis CCDC5079]
Length=309

 Score =  624 bits (1609),  Expect = 9e-177, Method: Compositional matrix adjust.
 Identities = 308/309 (99%), Positives = 308/309 (99%), Gaps = 0/309 (0%)

Query  64   MKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPII  123
            MKDRPALYMVECARARGDIAPGAAIVEST GTLGLGLALAGKVYRHPVTLVTDPGLEPII
Sbjct  1    MKDRPALYMVECARARGDIAPGAAIVESTSGTLGLGLALAGKVYRHPVTLVTDPGLEPII  60

Query  124  ARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLA  183
            ARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLA
Sbjct  61   ARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLA  120

Query  184  LELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMR  243
            LELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMR
Sbjct  121  LELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMR  180

Query  244  GLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNL  303
            GLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNL
Sbjct  181  GLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNL  240

Query  304  PADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTT  363
            PADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTT
Sbjct  241  PADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTT  300

Query  364  VIDPTQVVS  372
            VIDPTQVVS
Sbjct  301  VIDPTQVVS  309


>gi|315441574|ref|YP_004074451.1| cysteine synthase [Mycobacterium sp. Spyr1]
 gi|315265229|gb|ADU01970.1| cysteine synthase [Mycobacterium sp. Spyr1]
Length=369

 Score =  546 bits (1406),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 267/350 (77%), Positives = 294/350 (84%), Gaps = 2/350 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GRN    TMVGNTPVL I   S  SD  RGFWAKLEGFNPGGMKDRPA++MVE A ARGD
Sbjct  21   GRNHRLATMVGNTPVLRIS--SPFSDDQRGFWAKLEGFNPGGMKDRPAMHMVEQATARGD  78

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            + PGA IVEST GTLGLGLA AG VYRHPVTLV DPG+EP++ RML+AYGA +D+VT+PH
Sbjct  79   LRPGARIVESTSGTLGLGLAFAGTVYRHPVTLVADPGMEPMMHRMLSAYGADIDVVTEPH  138

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
            P GGWQQAR+DRVA+L+A +P +W P+QY NPDNV AY+ LALEL AQLG IDVLVCSVG
Sbjct  139  PQGGWQQARRDRVAELLAAHPHSWYPDQYNNPDNVEAYQGLALELHAQLGEIDVLVCSVG  198

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLR+FNPD+RLIGVDT+GSTIFGQPA+ RLMRGLGSSIYPRNVDY AFDE
Sbjct  199  TGGHSAGVARVLRQFNPDLRLIGVDTVGSTIFGQPAATRLMRGLGSSIYPRNVDYDAFDE  258

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP EAVWACR+LAATHYASGGWSVGAVALVAGW AR  P DT IAAVFPDGPQRYF
Sbjct  259  VHWVAPAEAVWACRTLAATHYASGGWSVGAVALVAGWVARTHPVDTAIAAVFPDGPQRYF  318

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            DT+YND YC +H L+GGQPP EP  I  P D VV  WTR   V+DP + V
Sbjct  319  DTVYNDDYCRQHGLVGGQPPEEPAVITDPTDQVVHSWTRCLHVVDPVRSV  368


>gi|126437127|ref|YP_001072818.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. JLS]
 gi|126236927|gb|ABO00328.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. JLS]
Length=393

 Score =  534 bits (1375),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 260/351 (75%), Positives = 292/351 (84%), Gaps = 2/351 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GRN  P TMVG TPVL I   +  +  +RGFWAKLEGFNPGGMKDRPAL+MVE AR+RG 
Sbjct  44   GRNERPATMVGQTPVLRIS--APFTSEERGFWAKLEGFNPGGMKDRPALHMVERARSRGA  101

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            +APGA IVEST GTLGLGLALAG VY HPVTLVTDPG+EPII  ML A+GA +++VT+PH
Sbjct  102  LAPGARIVESTSGTLGLGLALAGTVYGHPVTLVTDPGMEPIIQNMLAAFGADIELVTEPH  161

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
            P GGWQQAR+DRV +++A  P AW+P+QY NPDNV AYR LALEL  QLG +DVLVCSVG
Sbjct  162  PQGGWQQARRDRVQKILATDPRAWHPDQYSNPDNVEAYRGLALELNEQLGAVDVLVCSVG  221

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLREFNP +RLIGVDT+GSTIFGQPA++RLMRGLGSSIYP NVDY+AF+E
Sbjct  222  TGGHSAGVARVLREFNPQLRLIGVDTVGSTIFGQPAASRLMRGLGSSIYPGNVDYQAFNE  281

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP E+VWACR+LAATHYASGGWSVGAVALVAGW ARN PA  T+AA+FPDGPQRYF
Sbjct  282  VHWVAPAESVWACRTLAATHYASGGWSVGAVALVAGWVARNSPAGATVAAIFPDGPQRYF  341

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVVS  372
            DTIYND YC  H LL   PP  P  I  P+   VT WTR TTV+DPT+V S
Sbjct  342  DTIYNDDYCRAHGLLDAAPPRHPATIEDPMTQTVTAWTRCTTVVDPTEVQS  392


>gi|226349448|ref|YP_002776562.1| putative cysteine synthase [Rhodococcus opacus B4]
 gi|226245363|dbj|BAH55710.1| putative cysteine synthase [Rhodococcus opacus B4]
Length=370

 Score =  532 bits (1371),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 258/353 (74%), Positives = 291/353 (83%), Gaps = 2/353 (0%)

Query  20   TPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARAR  79
            T GR   P TMVGNTPVLWI E    +D  RGFWAKLEG NPGGMKDRPAL+MVE A+AR
Sbjct  20   TAGRCPQPSTMVGNTPVLWIGE--PFADTGRGFWAKLEGSNPGGMKDRPALHMVEKAKAR  77

Query  80   GDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQ  139
            GD+APGA I+EST GTLGLGLALAG  + HPVTLVTDPGLEPI+  ML AYGA V++VT 
Sbjct  78   GDLAPGAMIIESTSGTLGLGLALAGITHHHPVTLVTDPGLEPIVHNMLAAYGAHVELVTT  137

Query  140  PHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCS  199
            PHP GGWQQAR+++V +L++ +PG+W P+QY NPDNV AY SLALEL+AQLGR+D LVCS
Sbjct  138  PHPTGGWQQARREKVRELLSAHPGSWCPDQYTNPDNVDAYESLALELIAQLGRVDTLVCS  197

Query  200  VGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAF  259
            VGTGGHSAGVARVLR F PD++L+GVDT+GSTIFGQPA  RLMRGLGSSIYP N+DY AF
Sbjct  198  VGTGGHSAGVARVLRRFCPDLKLVGVDTVGSTIFGQPAGTRLMRGLGSSIYPDNIDYPAF  257

Query  260  DEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQR  319
            DEVHWVAP EAVW+CR+LAATH+ASGGWSVGAVAL AGW AR  P +T +AA+FPDGPQR
Sbjct  258  DEVHWVAPHEAVWSCRTLAATHHASGGWSVGAVALTAGWIARTSPPETRVAAIFPDGPQR  317

Query  320  YFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVVS  372
            YFDTIYND YC EH LL   PPTEP  I  P D VV  WTR  TV+DPT+ VS
Sbjct  318  YFDTIYNDDYCAEHGLLDANPPTEPATIDHPTDHVVQSWTRCATVVDPTESVS  370


>gi|315446726|ref|YP_004079605.1| cysteine synthase [Mycobacterium sp. Spyr1]
 gi|315265029|gb|ADU01771.1| cysteine synthase [Mycobacterium sp. Spyr1]
Length=371

 Score =  531 bits (1369),  Expect = 6e-149, Method: Compositional matrix adjust.
 Identities = 265/349 (76%), Positives = 289/349 (83%), Gaps = 1/349 (0%)

Query  23   RNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDI  82
            R   PGTM+GNTPVL I     + D   GFWAKLEGFNPGGMKDRPA++MVE  RARGD+
Sbjct  22   RFDRPGTMIGNTPVLRI-GAPFSDDNSHGFWAKLEGFNPGGMKDRPAMHMVERGRARGDL  80

Query  83   APGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHP  142
              G  IVEST GTLGLGLALAG VY HPVTLVTDPGLEPII+RMLTAYGA VD+VT+PHP
Sbjct  81   RAGGRIVESTSGTLGLGLALAGTVYGHPVTLVTDPGLEPIISRMLTAYGADVDVVTEPHP  140

Query  143  VGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGT  202
             GGWQQAR++RV +++   P AW P+QY NPDNV AYR LA EL AQLG IDVLVCSVGT
Sbjct  141  AGGWQQARRNRVMEILESDPSAWYPDQYNNPDNVDAYRGLADELSAQLGTIDVLVCSVGT  200

Query  203  GGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEV  262
            GGHSAGVARVLRE NPD+RLIGVDTIGSTIFGQPA +RLMRGLGSSIYPRNVDY AFDEV
Sbjct  201  GGHSAGVARVLRETNPDLRLIGVDTIGSTIFGQPAQSRLMRGLGSSIYPRNVDYAAFDEV  260

Query  263  HWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFD  322
            HWVAP EAVWACR+LA+THYASGGWSVGAVALVAGW AR  P+ TT+AAVFPDGPQRYFD
Sbjct  261  HWVAPAEAVWACRALASTHYASGGWSVGAVALVAGWVARTNPSSTTVAAVFPDGPQRYFD  320

Query  323  TIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            TIYND YC+ H LLGG PP  P  IA P   +VT WTR++ V DPT VV
Sbjct  321  TIYNDDYCHSHGLLGGAPPRNPKVIADPRGRIVTSWTRTSAVTDPTAVV  369


>gi|54027728|ref|YP_121969.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
 gi|54019236|dbj|BAD60605.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
Length=375

 Score =  524 bits (1349),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 257/353 (73%), Positives = 288/353 (82%), Gaps = 2/353 (0%)

Query  19   VTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARA  78
            V P   R P +++GNTPVLW+   +  +   RGFWAKLEGFNPGGMKDRPAL+MV  A  
Sbjct  18   VAPAPARFPQSLIGNTPVLWVG--APLAPKGRGFWAKLEGFNPGGMKDRPALHMVLKAEQ  75

Query  79   RGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVT  138
            RGD+ PGA I+EST GTLGLGLALAG    HPV +VTDPGLEPI+ARMLTAYG  VD+VT
Sbjct  76   RGDLTPGARIIESTSGTLGLGLALAGIATHHPVMVVTDPGLEPIVARMLTAYGTQVDVVT  135

Query  139  QPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVC  198
            + HP GGWQQAR+DRVA+L+A  P AW P+QY NPDNV  Y SLALELV QLG +DVLVC
Sbjct  136  EAHPAGGWQQARRDRVAELLAADPDAWCPDQYSNPDNVDGYESLALELVEQLGGVDVLVC  195

Query  199  SVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRA  258
            +VGTGGHSAGVARVLR+FNP+M+LIGVDT+ STIFGQPA  RLMRGLGSSIYP NVDY A
Sbjct  196  AVGTGGHSAGVARVLRQFNPEMKLIGVDTVASTIFGQPAGPRLMRGLGSSIYPVNVDYDA  255

Query  259  FDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQ  318
            FDEVHWVAP EAVWACR+LAATH+A+GGWSVGAVALVAGWAAR    DT IAAVFPDGP 
Sbjct  256  FDEVHWVAPSEAVWACRTLAATHHATGGWSVGAVALVAGWAARTHDTDTRIAAVFPDGPH  315

Query  319  RYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            RYFDTIYNDAYC+EH LL   PP EPD IA P + VV  WTR+TTV+DP Q +
Sbjct  316  RYFDTIYNDAYCDEHGLLDADPPVEPDTIAHPAERVVRSWTRTTTVVDPRQFI  368


>gi|120406798|ref|YP_956627.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
vanbaalenii PYR-1]
 gi|119959616|gb|ABM16621.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
vanbaalenii PYR-1]
Length=368

 Score =  522 bits (1344),  Expect = 4e-146, Method: Compositional matrix adjust.
 Identities = 257/350 (74%), Positives = 289/350 (83%), Gaps = 2/350 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GR   P TMVG TPVL I      +D DRGFWAKLEGFNPGGMKDRPAL+MV+ ARA G 
Sbjct  19   GRYERPATMVGQTPVLRI--TVPFTDADRGFWAKLEGFNPGGMKDRPALHMVQRARAAGA  76

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            + PGA IVEST GTLGLGLALAG  Y HPVTLVTDPGLEPI+ARMLTA+GA +++V +PH
Sbjct  77   LKPGARIVESTSGTLGLGLALAGTGYGHPVTLVTDPGLEPIVARMLTAFGAHIELVVEPH  136

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
              GGWQQAR++RV Q+++  P AW+P+QY NPDNV AYR LA EL+ QLG +DVLVCSVG
Sbjct  137  QHGGWQQARRERVQQILSSDPHAWHPDQYNNPDNVEAYRGLAHELIDQLGSVDVLVCSVG  196

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLRE +P +RLIGVDT+GSTIFGQPA  RLMRGLGSSIYP NVDY AFDE
Sbjct  197  TGGHSAGVARVLRETDPQLRLIGVDTVGSTIFGQPAGARLMRGLGSSIYPGNVDYAAFDE  256

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP EAVWACR+LAATHYASGGWSVGAVALVAGWAARN P  TT+AA+FPDGPQRYF
Sbjct  257  VHWVAPAEAVWACRTLAATHYASGGWSVGAVALVAGWAARNSPPATTVAAIFPDGPQRYF  316

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            DT+YND YC  H LLGG PP+ P  IA PL  V T W+R T ++DPT+V+
Sbjct  317  DTVYNDDYCRAHHLLGGAPPSHPATIADPLAQVATAWSRCTRIVDPTRVM  366


>gi|54027672|ref|YP_121913.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
 gi|54019180|dbj|BAD60549.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
Length=375

 Score =  521 bits (1343),  Expect = 5e-146, Method: Compositional matrix adjust.
 Identities = 256/351 (73%), Positives = 286/351 (82%), Gaps = 2/351 (0%)

Query  21   PGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARG  80
            P   R+P +++GNTPVLW+   +  +   RGFWAKLEGFNPGGMKDRPAL+MV  A  RG
Sbjct  20   PVAARYPHSLIGNTPVLWVG--APLAPQGRGFWAKLEGFNPGGMKDRPALHMVRKAEQRG  77

Query  81   DIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQP  140
            D+APGA I+EST GTLGLGLALAG    HPVT+VTDPGLEPI+ARMLTAYG  VD+VT+ 
Sbjct  78   DLAPGARIIESTSGTLGLGLALAGIATHHPVTVVTDPGLEPIVARMLTAYGTQVDVVTEA  137

Query  141  HPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSV  200
            HP GGWQQAR+DRVA+L+A  P AW P+QY NPDNV +Y SLALELV QLG +DVLVC+V
Sbjct  138  HPTGGWQQARRDRVAELLAGEPDAWCPDQYSNPDNVDSYESLALELVEQLGEVDVLVCAV  197

Query  201  GTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFD  260
            GTGGHSAGVARVLR FNP M+LIGVDT+ STIFGQPA  RLMRGLGSSIYP NVDY AFD
Sbjct  198  GTGGHSAGVARVLRRFNPGMKLIGVDTVASTIFGQPAGLRLMRGLGSSIYPINVDYDAFD  257

Query  261  EVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRY  320
            EVHWVAP EAVWACR+LAATH+A+GGWSVGAV LVAGWAAR   ADT IAAVFPDGP RY
Sbjct  258  EVHWVAPSEAVWACRTLAATHHATGGWSVGAVGLVAGWAARTHDADTRIAAVFPDGPHRY  317

Query  321  FDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            FDT+YND YC EH LL   PP EPD IA P + VV  WTR TTV+DP Q +
Sbjct  318  FDTVYNDTYCEEHGLLDADPPVEPDTIAHPAERVVRSWTRCTTVVDPRQFI  368


>gi|108801161|ref|YP_641358.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. MCS]
 gi|119870293|ref|YP_940245.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. KMS]
 gi|108771580|gb|ABG10302.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. MCS]
 gi|119696382|gb|ABL93455.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. KMS]
Length=369

 Score =  518 bits (1333),  Expect = 8e-145, Method: Compositional matrix adjust.
 Identities = 261/350 (75%), Positives = 287/350 (82%), Gaps = 2/350 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GR   PGTMVGNTPVL I     TSD +RGFWAKLEGFNPGGMKDRPA++MVE  RA G 
Sbjct  21   GRYERPGTMVGNTPVLRI-AAPFTSD-ERGFWAKLEGFNPGGMKDRPAMHMVERGRACGA  78

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            + PGA IVEST GTLGLGLALAG  Y HPVTLVTDPG+EP+IARML+AYGA ++MVT+PH
Sbjct  79   LRPGATIVESTSGTLGLGLALAGTAYAHPVTLVTDPGMEPLIARMLSAYGARIEMVTEPH  138

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
            P GGWQ+AR+DRV Q+++  P AW P+QY NPDNV AYR LALEL AQLG IDVLVCSVG
Sbjct  139  PDGGWQRARQDRVQQILSADPHAWYPDQYNNPDNVEAYRPLALELQAQLGHIDVLVCSVG  198

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLRE NP +RLIGVDTIGSTIFGQPAS RLMRGLGSSIYP NVDY AF E
Sbjct  199  TGGHSAGVARVLRESNPALRLIGVDTIGSTIFGQPASTRLMRGLGSSIYPGNVDYEAFSE  258

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP +AVWACR+LAATHY SGGWSVGAVALVAGWAAR LP  +TIAA+FPDGPQRYF
Sbjct  259  VHWVAPEDAVWACRTLAATHYTSGGWSVGAVALVAGWAARTLPDSSTIAAIFPDGPQRYF  318

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            DT+YND YC  H LL   PP  P  I  P + VV+ WTR T V+DP  V+
Sbjct  319  DTVYNDDYCRAHGLLDHTPPAGPAVIGHPRERVVSSWTRCTDVVDPMAVL  368


>gi|108798415|ref|YP_638612.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. MCS]
 gi|119867512|ref|YP_937464.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. KMS]
 gi|108768834|gb|ABG07556.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. MCS]
 gi|119693601|gb|ABL90674.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. KMS]
Length=371

 Score =  517 bits (1331),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 260/348 (75%), Positives = 284/348 (82%), Gaps = 2/348 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GR   P TMVG TPVL I E    S   RGFWAKLEGFNPGGMKDRPAL+MV+ ARARG+
Sbjct  22   GRFERPATMVGQTPVLRIGEPFTPSG--RGFWAKLEGFNPGGMKDRPALHMVQRARARGE  79

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            + P A IVEST GTLGLGLALAG VY HPVTLVTDPG+EPII  ML A+GA +++VTQPH
Sbjct  80   LRPDARIVESTSGTLGLGLALAGTVYGHPVTLVTDPGMEPIIQHMLAAFGAQIELVTQPH  139

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
            P GGWQ+AR+ RV +L+A  P AW+P+QY NPDNV AYR LA+EL+ QLG +DVLVCSVG
Sbjct  140  PQGGWQEARRQRVGELLAADPQAWHPDQYSNPDNVEAYRGLAMELIEQLGAVDVLVCSVG  199

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLRE NP MRLIGVDTIGSTIFGQPAS RLMRGLGSSIYP NVDY AF+E
Sbjct  200  TGGHSAGVARVLRERNPQMRLIGVDTIGSTIFGQPASTRLMRGLGSSIYPGNVDYDAFNE  259

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP EAVWACR+LA+THYASGGWSVGAVALVAGWAAR   + TT+AAVFPD PQRYF
Sbjct  260  VHWVAPSEAVWACRTLASTHYASGGWSVGAVALVAGWAARQGDSGTTVAAVFPDNPQRYF  319

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQ  369
            DTIYND YC  H LL   PP+EP  I  PL   VT WTR  TVIDPTQ
Sbjct  320  DTIYNDDYCRTHGLLDTAPPSEPATIEDPLAHTVTAWTRCATVIDPTQ  367


>gi|126436995|ref|YP_001072686.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
sp. JLS]
 gi|126236795|gb|ABO00196.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
sp. JLS]
Length=369

 Score =  516 bits (1329),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 261/350 (75%), Positives = 287/350 (82%), Gaps = 2/350 (0%)

Query  22   GRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGD  81
            GR   PGTMVGNTPVL I     TSD +RGFWAKLEGFNPGGMKDRPA++MVE  RA G 
Sbjct  21   GRYERPGTMVGNTPVLRI-AAPFTSD-ERGFWAKLEGFNPGGMKDRPAMHMVERGRACGA  78

Query  82   IAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPH  141
            + PGA IVEST GTLGLGLALAG  Y HPVTLVTDPG+EP+IARML+AYGA ++MVT+PH
Sbjct  79   LRPGATIVESTSGTLGLGLALAGTAYAHPVTLVTDPGMEPLIARMLSAYGARIEMVTEPH  138

Query  142  PVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVG  201
            P GGWQ+AR+DRV Q+++  P AW P+QY NPDNV AYR LALEL AQLG IDVLVCSVG
Sbjct  139  PDGGWQRARQDRVQQILSADPHAWYPDQYNNPDNVEAYRPLALELQAQLGHIDVLVCSVG  198

Query  202  TGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDE  261
            TGGHSAGVARVLRE NP +RLIGVDTIGSTIFGQPAS RLMRGLGSSIYP NVDY AF E
Sbjct  199  TGGHSAGVARVLRESNPALRLIGVDTIGSTIFGQPASTRLMRGLGSSIYPGNVDYGAFSE  258

Query  262  VHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYF  321
            VHWVAP +AVWACR+LAATHY SGGWSVGAVALVAGWAAR LP  +TIAA+FPDGPQRYF
Sbjct  259  VHWVAPEDAVWACRTLAATHYTSGGWSVGAVALVAGWAARTLPDSSTIAAIFPDGPQRYF  318

Query  322  DTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVV  371
            DT+YND YC  H LL   PP  P  I  P + VV+ WTR T V+DP  V+
Sbjct  319  DTVYNDDYCRAHGLLDHTPPAGPAVIGHPRERVVSSWTRCTDVVDPMAVL  368


>gi|169628366|ref|YP_001702015.1| cysteine synthase A CysK2 [Mycobacterium abscessus ATCC 19977]
 gi|169240333|emb|CAM61361.1| Possible cysteine synthase A CysK2 [Mycobacterium abscessus]
Length=417

 Score =  498 bits (1282),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 247/341 (73%), Positives = 276/341 (81%), Gaps = 2/341 (0%)

Query  27   PGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGA  86
            P T+VGNTPVLW+ E   T  P  GFWAKLEG NP GMKDRPAL+M+E ARARGD+ PGA
Sbjct  74   PNTLVGNTPVLWVSEPFST--PGTGFWAKLEGHNPNGMKDRPALHMIEQARARGDLKPGA  131

Query  87   AIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGW  146
             IVEST GTLGLGLALAG +YRHPVTLVTDPGLEPI++ ML AYGA VD+VT+PHP+GGW
Sbjct  132  MIVESTSGTLGLGLALAGIIYRHPVTLVTDPGLEPIVSSMLNAYGAQVDIVTEPHPIGGW  191

Query  147  QQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHS  206
            QQARKDRVAQL+A  P +W P+QY NPDNV AYR LA EL+ QLG +D LVCSVGTGGHS
Sbjct  192  QQARKDRVAQLLAAEPDSWCPDQYQNPDNVDAYRGLAEELIDQLGTVDTLVCSVGTGGHS  251

Query  207  AGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVA  266
            +GV RVLRE NP++RL+GVDTIGSTIFGQPA +RLMRGLGSSIYP NVDY AFDE HWVA
Sbjct  252  SGVGRVLREHNPNLRLVGVDTIGSTIFGQPAGSRLMRGLGSSIYPGNVDYPAFDEAHWVA  311

Query  267  PPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYN  326
            P EAVWA R+LAAT++ASGGWSVGAVALVAGW AR       IAA+FPDGP RY  TIY+
Sbjct  312  PNEAVWAARTLAATYHASGGWSVGAVALVAGWVARTSDPGARIAAIFPDGPMRYHGTIYD  371

Query  327  DAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            D YC  H+LL   P  +PD I  P + VV RWTR T VIDP
Sbjct  372  DDYCRSHDLLDRPPAQDPDVIDDPSERVVDRWTRLTRVIDP  412


>gi|169627555|ref|YP_001701204.1| cysteine synthase [Mycobacterium abscessus ATCC 19977]
 gi|169239522|emb|CAM60550.1| Possible cysteine synthase [Mycobacterium abscessus]
Length=366

 Score =  497 bits (1280),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 247/341 (73%), Positives = 276/341 (81%), Gaps = 2/341 (0%)

Query  27   PGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGA  86
            P T+VGNTPVLW+ E    S P  GFWAKLE  NP GMKDRPALYMVE AR RGD+ PGA
Sbjct  23   PNTLVGNTPVLWVSE--PFSGPGTGFWAKLEAHNPNGMKDRPALYMVERARERGDLKPGA  80

Query  87   AIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGW  146
             IVEST GTLGLGLALAG +YRHPVTLVTDPGLEPII +MLTAYGA VD+VT+PHP+GGW
Sbjct  81   MIVESTSGTLGLGLALAGIIYRHPVTLVTDPGLEPIIVQMLTAYGAVVDIVTEPHPIGGW  140

Query  147  QQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHS  206
            QQARKDRVA+++A  P +W P+QY NPDNV AYR +A EL+ QLG +D LVCSVGTGGHS
Sbjct  141  QQARKDRVAEILAAEPDSWCPDQYQNPDNVDAYRGVAEELIDQLGTVDTLVCSVGTGGHS  200

Query  207  AGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVA  266
            +GV RVLRE NP++RL+GVDTIGSTIFGQPAS RLMRGLGSSIYP NVDYRAFDE HWVA
Sbjct  201  SGVGRVLREHNPNLRLVGVDTIGSTIFGQPASTRLMRGLGSSIYPGNVDYRAFDEAHWVA  260

Query  267  PPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYN  326
            P EAVWA R+LAA+++ASGGWSVGAVALVAGW AR     T +AA+FPDGP RY  TIY+
Sbjct  261  PNEAVWAARTLAASYHASGGWSVGAVALVAGWVARTSEPGTRVAAIFPDGPMRYHGTIYD  320

Query  327  DAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            D YC  H+LL   P  +PD I  P   VV RWTR T VIDP
Sbjct  321  DDYCRSHDLLDRPPAQDPDVIDDPSQRVVDRWTRLTHVIDP  361


>gi|271966318|ref|YP_003340514.1| cysteine synthase-like protein [Streptosporangium roseum DSM 
43021]
 gi|270509493|gb|ACZ87771.1| Cysteine synthase-like protein [Streptosporangium roseum DSM 
43021]
Length=379

 Score =  494 bits (1272),  Expect = 8e-138, Method: Compositional matrix adjust.
 Identities = 243/355 (69%), Positives = 283/355 (80%), Gaps = 3/355 (0%)

Query  14   PEGYQVTPGRNRH-PGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYM  72
            P   Q+  G   H P  +VGNTPVLW+PE+   S  +RGFWAKLEG NPGG+KDR ALY+
Sbjct  13   PSLSQMITGSTCHTPEHVVGNTPVLWVPEI--VSGQERGFWAKLEGNNPGGIKDRSALYI  70

Query  73   VECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGA  132
            VE AR RG++ PGA IVEST GT GLGLALAG VY HPVTLVTDPG+EP++ R+L+AYGA
Sbjct  71   VERARDRGELRPGAPIVESTSGTFGLGLALAGIVYGHPVTLVTDPGMEPLMCRLLSAYGA  130

Query  133  GVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGR  192
             V +V +PHPVGGWQQAR++RV +L+ E+P A+ P+QY NPDN+ AY  LA EL  QLGR
Sbjct  131  RVVIVAEPHPVGGWQQARRERVRRLLGEHPDAYCPDQYNNPDNITAYAGLATELAGQLGR  190

Query  193  IDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPR  252
            IDVLVCSVGTGGHSAGV+R LR F PD+RL+GVDTIGSTIFGQPA +RLMRGLGSSIYPR
Sbjct  191  IDVLVCSVGTGGHSAGVSRALRRFYPDLRLVGVDTIGSTIFGQPARSRLMRGLGSSIYPR  250

Query  253  NVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAV  312
            NVDY AF+EVHWVAPPEAVWACR LAA  YA+GGWSVGAVALV+ W AR LP+ T IAA+
Sbjct  251  NVDYEAFNEVHWVAPPEAVWACRRLAALRYATGGWSVGAVALVSSWLARTLPSHTRIAAI  310

Query  313  FPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            FPDGP RYFDT++ND YC  H LLG    T+P+ I  P +  +T WTR  TV+DP
Sbjct  311  FPDGPHRYFDTVFNDDYCAAHGLLGSPVTTDPEVIDHPAERELTSWTRCATVVDP  365


>gi|302546893|ref|ZP_07299235.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
hygroscopicus ATCC 53653]
 gi|302464511|gb|EFL27604.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
himastatinicus ATCC 53653]
Length=381

 Score =  492 bits (1267),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 244/351 (70%), Positives = 281/351 (81%), Gaps = 11/351 (3%)

Query  21   PGRNRHPGTMVGNTPVLWIPELSGTSDP----DRGFWAKLEGFNPGGMKDRPALYMVECA  76
            P R+   G +VG+TPVL I      SDP    DRGFWAKLEGFNPGG+KDRP LYMVE A
Sbjct  12   PARSALSG-LVGDTPVLRI------SDPLTPADRGFWAKLEGFNPGGIKDRPGLYMVERA  64

Query  77   RARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDM  136
            RARGD+ PGA I+EST GTLGLGLALAG VY HPVTLVTDPGLE  + ++LT YGA VD+
Sbjct  65   RARGDLRPGARIIESTSGTLGLGLALAGMVYGHPVTLVTDPGLERSMTQLLTTYGAQVDV  124

Query  137  VTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVL  196
            V++PHP GGWQQAR++RVAQLMA++PG+W P+QY NPDN  AY  LALEL ++LG +DVL
Sbjct  125  VSEPHPTGGWQQARRERVAQLMAQHPGSWCPDQYNNPDNTTAYTPLALELASELGHLDVL  184

Query  197  VCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDY  256
            VCSVGTGGHSAGV+RVL+   P+++L+GVDTIGSTIFGQPA  RLMRGLGSSIYPRNV Y
Sbjct  185  VCSVGTGGHSAGVSRVLQALYPELKLVGVDTIGSTIFGQPARTRLMRGLGSSIYPRNVAY  244

Query  257  RAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDG  316
              F EVHWVAP EAVW CR LAA+HYA+GGWSVGAV+LVAGW AR LPADT IAA+FPDG
Sbjct  245  DNFSEVHWVAPAEAVWTCRRLAASHYATGGWSVGAVSLVAGWLARTLPADTKIAAIFPDG  304

Query  317  PQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            PQRY  T+Y+D YC  H LL   PP EP+ I    +  V+RWTR TTV+DP
Sbjct  305  PQRYLGTVYDDDYCAAHGLLDSPPPVEPETIGRLDEKEVSRWTRCTTVVDP  355


>gi|343924998|ref|ZP_08764533.1| putative cysteine synthase [Gordonia alkanivorans NBRC 16433]
 gi|343765138|dbj|GAA11459.1| putative cysteine synthase [Gordonia alkanivorans NBRC 16433]
Length=403

 Score =  486 bits (1252),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 239/341 (71%), Positives = 273/341 (81%), Gaps = 2/341 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VG TPVL I E    ++   GFWAKLEGFNPGGMKDRPAL+MVE ARARG++APGA I+
Sbjct  58   LVGGTPVLRIEE--PFAEHGHGFWAKLEGFNPGGMKDRPALHMVERARARGELAPGAQII  115

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG V+ HPVTLVTDPGLEPI+ +ML AYGA VD+V++PHPVGGWQQA
Sbjct  116  ESTSGTLGLGLALAGIVFGHPVTLVTDPGLEPILRQMLAAYGARVDVVSEPHPVGGWQQA  175

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV  L+A    AW P+QY NPDNV  Y SL +EL+AQL  IDVLVCSVGTGGHSAGV
Sbjct  176  RRDRVRALLALDEAAWCPDQYSNPDNVTGYSSLGVELIAQLRHIDVLVCSVGTGGHSAGV  235

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            A  LR+FNP++ ++GVDTIGSTIFGQPA +R+MRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  236  AHTLRQFNPELEVVGVDTIGSTIFGQPAQSRIMRGLGSSIYPRNVAYDQFSEVHWVAPAE  295

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVWACR+LAAT YA+GGWSVGAVALV+GW AR   ADT IAAVFPDGP RY+ TIYND Y
Sbjct  296  AVWACRTLAATQYATGGWSVGAVALVSGWLARTRSADTRIAAVFPDGPARYYGTIYNDEY  355

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQV  370
            C  H+L+    PT P  I  PL  V + WTR  T+IDPT +
Sbjct  356  CQAHDLMDAPAPTAPHTINDPLTQVASSWTRCPTIIDPTHM  396


>gi|145221493|ref|YP_001132171.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Mycobacterium 
gilvum PYR-GCK]
 gi|145213979|gb|ABP43383.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Mycobacterium 
gilvum PYR-GCK]
Length=371

 Score =  486 bits (1250),  Expect = 3e-135, Method: Compositional matrix adjust.
 Identities = 254/371 (69%), Positives = 290/371 (79%), Gaps = 8/371 (2%)

Query  1    VRSRQTRDRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFN  60
            +   Q  DR+       Q+  GR   P TMVG TPVL I   +  +  + GFWAKLEGFN
Sbjct  7    IHHAQDTDRFE------QLRLGRYERPATMVGQTPVLRIG--APFTAAEHGFWAKLEGFN  58

Query  61   PGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLE  120
            PGGMKDRPAL+MVE AR+RG + PGA IVEST GTLGLGLALAG VY HPVTLVTDPG+E
Sbjct  59   PGGMKDRPALHMVERARSRGKLVPGARIVESTSGTLGLGLALAGTVYGHPVTLVTDPGME  118

Query  121  PIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYR  180
            P+I  ML A+GA +++VT+PHP GGWQQAR +RV +++   P AW+P+QY NPDNV AYR
Sbjct  119  PMIQHMLAAFGAHIELVTEPHPRGGWQQARTERVHEILGTDPQAWHPDQYNNPDNVEAYR  178

Query  181  SLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNR  240
             LA+EL+ QLG +DVLVCSVGTGGHSAGVARVLRE+NP +RLIGVDT+GSTIFGQPA+ R
Sbjct  179  GLAMELIEQLGSVDVLVCSVGTGGHSAGVARVLREYNPGLRLIGVDTVGSTIFGQPATTR  238

Query  241  LMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAA  300
            LMRGLGSSIYP NVDY AF+EVHWVAP +AVWACR+LAATHYASGGWSVGAVA+VAGWAA
Sbjct  239  LMRGLGSSIYPGNVDYAAFNEVHWVAPADAVWACRTLAATHYASGGWSVGAVAVVAGWAA  298

Query  301  RNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTR  360
            R     TT+AA+FPDGPQRYFDTIYND YC  H LL   PP EP  I  PL   V  WTR
Sbjct  299  RGSDPGTTVAAIFPDGPQRYFDTIYNDEYCRTHGLLDKAPPNEPATIDHPLRHAVKAWTR  358

Query  361  STTVIDPTQVV  371
               V+DPTQVV
Sbjct  359  CPVVVDPTQVV  369


>gi|262202520|ref|YP_003273728.1| pyridoxal-5'-phosphate-dependent protein subunit beta [Gordonia 
bronchialis DSM 43247]
 gi|262085867|gb|ACY21835.1| Pyridoxal-5'-phosphate-dependent protein beta subunit [Gordonia 
bronchialis DSM 43247]
Length=378

 Score =  486 bits (1250),  Expect = 3e-135, Method: Compositional matrix adjust.
 Identities = 241/342 (71%), Positives = 274/342 (81%), Gaps = 3/342 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VG TPVL I E    ++  RGFWAKLEGFNPGGMKDRPAL+MVE ARAR ++APGA I+
Sbjct  32   LVGGTPVLRIEE--PFAEHGRGFWAKLEGFNPGGMKDRPALHMVERARAREELAPGAQII  89

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG V+ HPVTLVTDPGLEPI+ +ML AYGA VD+V+ PHPVGGWQQA
Sbjct  90   ESTSGTLGLGLALAGIVFGHPVTLVTDPGLEPILRQMLAAYGAQVDVVSDPHPVGGWQQA  149

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV  L+     AW P+QY NPDNV  Y SL +EL+AQL  IDVLVCSVGTGGHSAGV
Sbjct  150  RRDRVRTLLERDEAAWCPDQYSNPDNVTGYSSLGVELIAQLRHIDVLVCSVGTGGHSAGV  209

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            A  LR+FNP++ ++GVDTIGSTIFGQPA +R+MRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  210  AHTLRQFNPELEVVGVDTIGSTIFGQPAQSRIMRGLGSSIYPRNVAYDQFSEVHWVAPAE  269

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVWACR+LAAT YA+GGWSVGAVALV+GW AR   ADT IAAVFPDGP RY+ TIYND Y
Sbjct  270  AVWACRTLAATQYATGGWSVGAVALVSGWLARTRSADTRIAAVFPDGPARYYGTIYNDEY  329

Query  330  CNEHELLGG-QPPTEPDEIASPLDAVVTRWTRSTTVIDPTQV  370
            C  H+L+G   PPT P  I+ PL  V + WTR  T+IDPT V
Sbjct  330  CQAHDLIGAPAPPTAPHTISDPLTQVASSWTRCPTIIDPTCV  371


>gi|302538253|ref|ZP_07290595.1| cysteine synthase B [Streptomyces sp. C]
 gi|302447148|gb|EFL18964.1| cysteine synthase B [Streptomyces sp. C]
Length=364

 Score =  484 bits (1247),  Expect = 7e-135, Method: Compositional matrix adjust.
 Identities = 238/349 (69%), Positives = 275/349 (79%), Gaps = 2/349 (0%)

Query  19   VTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARA  78
            VTP        +VGNTP+L + E    +   RGFWAKLEGFNPGG+KDRP L+MVE ARA
Sbjct  8    VTPPARSGLSGLVGNTPLLRVSE--PLAPAGRGFWAKLEGFNPGGIKDRPGLHMVERARA  65

Query  79   RGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVT  138
            RG++ PGA I+EST GTLGLGLALAG V+ HPVTLVTDPGLEP + R+LTAYGA V++V+
Sbjct  66   RGELKPGARIIESTSGTLGLGLALAGMVHGHPVTLVTDPGLEPSMTRLLTAYGAQVNVVS  125

Query  139  QPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVC  198
            +PHP GGWQQAR+DRV QL+A++PG+W P+QY NPDN  AY  LALEL  +L  IDVLVC
Sbjct  126  EPHPTGGWQQARRDRVTQLLAQHPGSWCPDQYNNPDNTTAYTPLALELATELHHIDVLVC  185

Query  199  SVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRA  258
            SVGTGGHSAGV+RVLR+  P+++L+GVDT+GSTIFGQPA  RLMRGLGSSIYPRNV Y  
Sbjct  186  SVGTGGHSAGVSRVLRQLYPELKLVGVDTVGSTIFGQPARTRLMRGLGSSIYPRNVAYEQ  245

Query  259  FDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQ  318
            F EVHWVAP EAVW CR LAA+HYA+GGWSVGAVALVAGW AR LP DT IAAVFPDGPQ
Sbjct  246  FSEVHWVAPGEAVWTCRQLAASHYAAGGWSVGAVALVAGWLARTLPEDTRIAAVFPDGPQ  305

Query  319  RYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            RY  T+Y+D YC  H LL   P  EPD I    +  VTRWTR  +V+DP
Sbjct  306  RYLGTVYDDDYCAAHGLLDSPPTAEPDTIGRLDEKEVTRWTRCASVVDP  354


>gi|54027707|ref|YP_121948.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
 gi|54019215|dbj|BAD60584.1| putative pyridoxal-phosphate dependent enzyme [Nocardia farcinica 
IFM 10152]
Length=380

 Score =  481 bits (1239),  Expect = 6e-134, Method: Compositional matrix adjust.
 Identities = 245/366 (67%), Positives = 276/366 (76%), Gaps = 3/366 (0%)

Query  8    DRYRLLPEGYQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGG-MKD  66
            D     P     T  R   P T+VGNTPVLWI   +  +    GFWAKLE  NPGG MKD
Sbjct  6    DDLGFTPATLLTTGTRCLRPATLVGNTPVLWIG--APLAPRGHGFWAKLEAANPGGGMKD  63

Query  67   RPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARM  126
            RPAL MVE A  RGD+ PGA I+EST GT+GLGLALA   Y HP+TLV+DPG+EP++  M
Sbjct  64   RPALCMVERALGRGDLTPGARIIESTSGTMGLGLALAATTYGHPLTLVSDPGMEPLMCSM  123

Query  127  LTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALEL  186
            L AYGA VD V  PHPVGGWQQAR+DRV  L+A  P AW P+QY NPDN+ AY  LALEL
Sbjct  124  LAAYGATVDTVHAPHPVGGWQQARRDRVDALLATDPTAWCPDQYNNPDNIDAYSPLALEL  183

Query  187  VAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLG  246
            +AQLGR+DVLVCSVGTGGHSAG+ARVLR + P +RL+GVDTI STIFGQPA  RLMRGLG
Sbjct  184  IAQLGRVDVLVCSVGTGGHSAGIARVLRRYCPQLRLVGVDTIASTIFGQPAGTRLMRGLG  243

Query  247  SSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPAD  306
            SSIYP NVDY AFDEVHWVAP EAVWA R+LA TH+A+GGWSVGAVALVAGW A     D
Sbjct  244  SSIYPGNVDYAAFDEVHWVAPGEAVWAARTLARTHHATGGWSVGAVALVAGWTAATTNPD  303

Query  307  TTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVID  366
            T IAAVFPDGP RY+DT++ND YC  ++LL   PPTEP  IA P +AVVT WTR T VID
Sbjct  304  TRIAAVFPDGPHRYYDTVFNDNYCRVNDLLDHAPPTEPVTIADPAEAVVTSWTRCTNVID  363

Query  367  PTQVVS  372
            P Q+ S
Sbjct  364  PHQLQS  369


>gi|290963254|ref|YP_003494436.1| cysteine synthase A [Streptomyces scabiei 87.22]
 gi|260652780|emb|CBG75913.1| POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) 
(O-ACETYLSERINE (THIOL)-LYASE) (CSASE) [Streptomyces scabiei 
87.22]
Length=404

 Score =  480 bits (1236),  Expect = 2e-133, Method: Compositional matrix adjust.
 Identities = 232/338 (69%), Positives = 273/338 (81%), Gaps = 2/338 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VGNTP+L + +    ++ DRGFWAKLEGFNPGG+KDRP L+MVE ARARG++ PGA I+
Sbjct  23   LVGNTPLLHVSQ--PFTESDRGFWAKLEGFNPGGIKDRPGLHMVERARARGELQPGARII  80

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG VY HPVTLVTDPGLE  + R+LTAYGA V++V++PHP GGWQQA
Sbjct  81   ESTSGTLGLGLALAGMVYGHPVTLVTDPGLEMSMTRLLTAYGAQVNLVSEPHPTGGWQQA  140

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV +LM ++PG+W P+QY NPDN  AY  LALEL  +LG IDVLVCSVGTGGHSAGV
Sbjct  141  RRDRVGRLMEQHPGSWCPDQYNNPDNTTAYTPLALELATELGHIDVLVCSVGTGGHSAGV  200

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +RVL++  PD++L+GVDTIGSTIFGQPA  RLMRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  201  SRVLQQLYPDLKLVGVDTIGSTIFGQPARPRLMRGLGSSIYPRNVAYDNFSEVHWVAPAE  260

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVW CR LAA+HYA+GGWSVGAVA+VAGW AR LPAD+ IAA+FPDGPQRY  T+Y+D Y
Sbjct  261  AVWNCRRLAASHYATGGWSVGAVAMVAGWLARTLPADSRIAAIFPDGPQRYLGTVYDDDY  320

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            C  H LL   P  EP+ +    +  +TRWTR   VIDP
Sbjct  321  CAAHGLLDAPPAPEPEVVGRLDEKEITRWTRCENVIDP  358


>gi|294813546|ref|ZP_06772189.1| cysteine synthase a CysK2 [Streptomyces clavuligerus ATCC 27064]
 gi|326442046|ref|ZP_08216780.1| cysteine synthase A [Streptomyces clavuligerus ATCC 27064]
 gi|294326145|gb|EFG07788.1| cysteine synthase a CysK2 [Streptomyces clavuligerus ATCC 27064]
Length=409

 Score =  473 bits (1218),  Expect = 2e-131, Method: Compositional matrix adjust.
 Identities = 235/343 (69%), Positives = 272/343 (80%), Gaps = 2/343 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VGNTP+L + E    +  +RGFWAKLEGFNPGG+KDRPAL+MVE ARARGD+ PG  I+
Sbjct  35   LVGNTPLLRVTEP--FTAGERGFWAKLEGFNPGGIKDRPALHMVERARARGDLRPGGRII  92

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG VY HPVTLVTDPGLE  + R+L AYGA V++V++ HP GGWQQA
Sbjct  93   ESTSGTLGLGLALAGMVYGHPVTLVTDPGLEGSMTRLLNAYGAQVNVVSEAHPTGGWQQA  152

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV +L+ +YPG+W P+QY NPDN  AY  LALEL A+L  IDVLVCSVGTGGHSAGV
Sbjct  153  RRDRVNRLLEQYPGSWCPDQYNNPDNTTAYTPLALELAAELRHIDVLVCSVGTGGHSAGV  212

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +RVLR+  P +RLIGVDTIGSTIFGQ A  RLMRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  213  SRVLRQLYPRLRLIGVDTIGSTIFGQEARPRLMRGLGSSIYPRNVAYDHFSEVHWVAPAE  272

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVW CR+LA +HYA+GGWSVGAVALVAGW AR LPADT IAAVFPDGPQRY  T+Y+D Y
Sbjct  273  AVWTCRALATSHYATGGWSVGAVALVAGWLARTLPADTRIAAVFPDGPQRYLGTVYDDDY  332

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQVVS  372
            C  H LL G P  EP+ +    +  +TRWTR  +V+DP  + S
Sbjct  333  CAAHGLLDGPPAPEPEVVGRMDEKQITRWTRCASVVDPLTLRS  375


>gi|329940468|ref|ZP_08289749.1| cysteine synthase A [Streptomyces griseoaurantiacus M045]
 gi|329300529|gb|EGG44426.1| cysteine synthase A [Streptomyces griseoaurantiacus M045]
Length=371

 Score =  472 bits (1215),  Expect = 4e-131, Method: Compositional matrix adjust.
 Identities = 240/351 (69%), Positives = 271/351 (78%), Gaps = 2/351 (0%)

Query  17   YQVTPGRNRHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECA  76
            Y   P   R P  +VGNTPVLWI E    +D  RGFWAKLEG NPGG+KDRPAL+MV  A
Sbjct  10   YAPAPTSARGPCDLVGNTPVLWIGEP--FADAGRGFWAKLEGANPGGIKDRPALHMVARA  67

Query  77   RARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDM  136
            RARGD++ GA I+ES+ GTLGLGLALAG  Y HPVT+VTDPGLEP I R LTAYGA V++
Sbjct  68   RARGDLSDGAPIIESSSGTLGLGLALAGITYGHPVTVVTDPGLEPPIRRALTAYGARVEL  127

Query  137  VTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVL  196
            VT  HPVGGWQQAR+++VA+L+ E+PGAW P+QY NPDNV AY  LA EL+AQLGRIDVL
Sbjct  128  VTAAHPVGGWQQARREKVAELLGEHPGAWCPDQYNNPDNVAAYAPLATELIAQLGRIDVL  187

Query  197  VCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDY  256
            V SVGTGGHSAG++  LR   PD+ LIGVD  GSTIFGQPA  RLMRGLGSSI+P NV +
Sbjct  188  VTSVGTGGHSAGISTALRHTFPDLELIGVDATGSTIFGQPAGQRLMRGLGSSIHPGNVAH  247

Query  257  RAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDG  316
             AF EVHWVAP EAV +CR LA  HYASGGWSVGAVALVAGWAAR  PA T IAA+FPDG
Sbjct  248  EAFTEVHWVAPAEAVHSCRLLARHHYASGGWSVGAVALVAGWAARTYPAGTRIAAIFPDG  307

Query  317  PQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            P RY DTIY+D +C+ H LL    P EPDEIA P +  V  WTR T+V DP
Sbjct  308  PHRYLDTIYSDGWCHGHHLLEAPVPVEPDEIADPGERAVVSWTRCTSVTDP  358


>gi|302555828|ref|ZP_07308170.1| cysteine synthase B [Streptomyces viridochromogenes DSM 40736]
 gi|302473446|gb|EFL36539.1| cysteine synthase B [Streptomyces viridochromogenes DSM 40736]
Length=366

 Score =  471 bits (1213),  Expect = 7e-131, Method: Compositional matrix adjust.
 Identities = 230/338 (69%), Positives = 269/338 (80%), Gaps = 2/338 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VGNTP+L + E    S   RGFWAKLEGFNPGG+KDRP L+MVE ARARGD+ PG  I+
Sbjct  4    LVGNTPLLRVSEPLAPSG--RGFWAKLEGFNPGGIKDRPGLHMVERARARGDLRPGGRII  61

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG VY HPVTLVTDPGLE  + R+LTAYGA V++V++PHP GGWQQA
Sbjct  62   ESTSGTLGLGLALAGMVYGHPVTLVTDPGLELSMTRLLTAYGAQVNVVSEPHPTGGWQQA  121

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV +L+ ++PG+W P+QY NPDNV AY  LALEL +++G IDVLVCSVGTGGHSAGV
Sbjct  122  RRDRVQRLLEQHPGSWCPDQYNNPDNVAAYTPLALELASEMGHIDVLVCSVGTGGHSAGV  181

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +RVLR+   ++ ++GVDTIGSTIFGQPA  RLMRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  182  SRVLRQLYSELTVVGVDTIGSTIFGQPARPRLMRGLGSSIYPRNVAYENFSEVHWVAPHE  241

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVW CR LAA+HYA+GGWSVGAVALVAGW AR +PAD  I A+FPDGPQRY  T+Y+D Y
Sbjct  242  AVWTCRQLAASHYATGGWSVGAVALVAGWLARTMPADARIVAIFPDGPQRYLGTVYDDDY  301

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            C  H LL   P  EP+ +    +  VTRWTR T V+DP
Sbjct  302  CAAHGLLESPPALEPELLGRLDEKEVTRWTRCTDVVDP  339


>gi|297153713|gb|ADI03425.1| cysteine synthase A [Streptomyces bingchenggensis BCW-1]
Length=366

 Score =  467 bits (1202),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 230/338 (69%), Positives = 266/338 (79%), Gaps = 2/338 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VGNTP+L + E    +    GFWAKLEGFNPGG+KDRP L+MVE ARARGD+ PG  I+
Sbjct  21   LVGNTPLLRVSE--PLAPAGHGFWAKLEGFNPGGIKDRPGLHMVERARARGDLRPGGRII  78

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG VY HPVTLVTDPGLE  + R+LTAYGA V++V++PHP GGWQQA
Sbjct  79   ESTSGTLGLGLALAGMVYGHPVTLVTDPGLELSMTRLLTAYGAQVNVVSEPHPTGGWQQA  138

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV +L  ++PG+W P+QY NPDNV AY  LALEL ++LG ID LVCSVGTGGHSAGV
Sbjct  139  RRDRVQRLRDQHPGSWCPDQYNNPDNVAAYTPLALELASELGHIDALVCSVGTGGHSAGV  198

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +RVLR+  P++++IGVDTIGSTIFGQPA  RLMRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  199  SRVLRQLYPELKVIGVDTIGSTIFGQPARPRLMRGLGSSIYPRNVAYDQFSEVHWVAPAE  258

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVW CR LAA+HYA+GGWSVGAVALVAGW AR  PADT I A+FPDGPQRY  T+Y+D Y
Sbjct  259  AVWTCRQLAASHYATGGWSVGAVALVAGWLARTSPADTRIVAIFPDGPQRYLGTVYDDDY  318

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            C  H LL   P  EP+   S  +    RWTR  TV+DP
Sbjct  319  CAAHGLLDAPPAPEPEVNGSLDEKEALRWTRCATVVDP  356


>gi|345009913|ref|YP_004812267.1| pyridoxal-5'-phosphate-dependent protein beta subunit [Streptomyces 
violaceusniger Tu 4113]
 gi|344036262|gb|AEM81987.1| Pyridoxal-5'-phosphate-dependent protein beta subunit [Streptomyces 
violaceusniger Tu 4113]
Length=384

 Score =  462 bits (1189),  Expect = 4e-128, Method: Compositional matrix adjust.
 Identities = 230/343 (68%), Positives = 264/343 (77%), Gaps = 6/343 (1%)

Query  27   PGTMVGNTPVLWIPELSGT--SDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAP  84
            P  +VG+TP+LWI    GT  +   RGFW KLEG NPGG+KDR AL+MV  AR RG + P
Sbjct  27   PAGLVGDTPILWI----GTPFTAAGRGFWTKLEGHNPGGIKDRTALHMVRAARERGQLLP  82

Query  85   GAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVG  144
             A I+EST GTLGLGL LAG  Y HPVT+VTDPG+EP++  +LTAYGA VD+V  PHP G
Sbjct  83   DAPIIESTSGTLGLGLTLAGSTYGHPVTVVTDPGMEPLMTGLLTAYGAEVDLVDTPHPTG  142

Query  145  GWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGG  204
            GWQ++R+ RV +L+A +P AW P+QY NPDNV AY  LA ELVAQLGRID LV SVGTGG
Sbjct  143  GWQESRRQRVEELLAAHPDAWCPDQYNNPDNVAAYAPLAHELVAQLGRIDTLVVSVGTGG  202

Query  205  HSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHW  264
            HSAG+A VLR F   +R++GVDT GSTIFGQP +NRLMRGLGSSIYPRNV Y  FDEVHW
Sbjct  203  HSAGIASVLRGFFRRLRVVGVDTTGSTIFGQPPANRLMRGLGSSIYPRNVAYDLFDEVHW  262

Query  265  VAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTI  324
            VA PEAVWACR LA  HYA+GGWSVGAVALVA W AR LPA+  I AVFPDGPQRY  T+
Sbjct  263  VAAPEAVWACRRLARDHYATGGWSVGAVALVARWLARTLPAEDRIVAVFPDGPQRYVGTV  322

Query  325  YNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            ++D YC +H LLG  PP +PDEIA   D +VTRWTR T V DP
Sbjct  323  FDDTYCRDHGLLGHLPPDDPDEIAHSGDRIVTRWTRCTHVTDP  365


>gi|134098308|ref|YP_001103969.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
 gi|291004272|ref|ZP_06562245.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133910931|emb|CAM01044.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
Length=375

 Score =  462 bits (1188),  Expect = 5e-128, Method: Compositional matrix adjust.
 Identities = 238/339 (71%), Positives = 270/339 (80%), Gaps = 2/339 (0%)

Query  31   VGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVE  90
            VG TPVLWI +    S    GFWAKLEGFNPGGMKDRPAL+MVE ARARG++APG  I+E
Sbjct  35   VGGTPVLWIDQPFNRSG--SGFWAKLEGFNPGGMKDRPALHMVEAARARGELAPGGTIIE  92

Query  91   STGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQAR  150
            ST GTLGLGLALAG  Y HPVTLVTDPG+EPI+  +L AYGA VD+VT+PHP GGWQ+AR
Sbjct  93   STSGTLGLGLALAGATYGHPVTLVTDPGMEPIMRTLLAAYGATVDVVTEPHPTGGWQEAR  152

Query  151  KDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVA  210
            ++RV  L+A   G++ P+QY NPDNV  YRSLALELVAQLGRIDVLVCSVGTGGHSAGV+
Sbjct  153  RERVRALLASNDGSFCPDQYNNPDNVAGYRSLALELVAQLGRIDVLVCSVGTGGHSAGVS  212

Query  211  RVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEA  270
            R LRE+ P ++L+GVDT GSTIFGQPA  RLMRGLGSSI+P NVD++AFDEVHWV   EA
Sbjct  213  RTLREYFPHLKLVGVDTTGSTIFGQPARKRLMRGLGSSIHPSNVDHQAFDEVHWVGAAEA  272

Query  271  VWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYC  330
            VWA R LAA H  SGGWSVGAVALVAGW AR  P++  IAAVFPDGP+RYFDT+YND YC
Sbjct  273  VWAARRLAAAHCTSGGWSVGAVALVAGWLARTEPSEARIAAVFPDGPERYFDTVYNDGYC  332

Query  331  NEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQ  369
             EH LL    P EP+ IA P    V RWTR  TV+DP +
Sbjct  333  REHGLLLDTAPVEPERIADPFSVKVERWTRCRTVLDPIR  371


>gi|302547627|ref|ZP_07299969.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
hygroscopicus ATCC 53653]
 gi|302465245|gb|EFL28338.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
himastatinicus ATCC 53653]
Length=373

 Score =  458 bits (1178),  Expect = 8e-127, Method: Compositional matrix adjust.
 Identities = 235/338 (70%), Positives = 269/338 (80%), Gaps = 2/338 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VGNTPVL + E    +   RGFWAKLEGFNPGG+KDRP L+MVE ARARGD+ PG AIV
Sbjct  16   LVGNTPVLRVSEPLAPAG--RGFWAKLEGFNPGGIKDRPGLHMVERARARGDLRPGGAIV  73

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG VY HPVTLVTDPGLEP + R+LTAYGA VDMVT+PHP GGWQQA
Sbjct  74   ESTSGTLGLGLALAGLVYGHPVTLVTDPGLEPSMTRLLTAYGAWVDMVTEPHPEGGWQQA  133

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R+DRV +L+A   G+W P+QY NPDN  AY  LALEL ++ G ID+LVCSVGTGGHSAGV
Sbjct  134  RRDRVTELLARDAGSWCPDQYNNPDNTAAYTPLALELASRFGHIDILVCSVGTGGHSAGV  193

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +RVLR+  P++ ++GVDT+GSTIFGQPA  RLMRGLGSSIYPRNV Y  F EVHWVAP E
Sbjct  194  SRVLRQLYPEITVVGVDTVGSTIFGQPARTRLMRGLGSSIYPRNVAYENFSEVHWVAPHE  253

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AVW CR LA++HYA+GGWSVGAVALVAGW AR  P+D  I AVFPDGPQRY DT+YND Y
Sbjct  254  AVWTCRQLASSHYATGGWSVGAVALVAGWLARTHPSDARIVAVFPDGPQRYLDTVYNDDY  313

Query  330  CNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            C  + LL   P  EPD +  P +  V RWTR T+V+DP
Sbjct  314  CAANGLLDQPPAPEPDTMGHPGEREVARWTRCTSVVDP  351


>gi|311893968|dbj|BAJ26376.1| putative cysteine synthase [Kitasatospora setae KM-6054]
Length=397

 Score =  457 bits (1176),  Expect = 1e-126, Method: Compositional matrix adjust.
 Identities = 232/343 (68%), Positives = 269/343 (79%), Gaps = 2/343 (0%)

Query  25   RHPGTMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAP  84
            R P  +VG+TPVLW+ E    + P RGFWAKLEG NPGG+KDRPAL+MV  AR RG++  
Sbjct  30   RTPAGLVGDTPVLWVGE--PFTAPGRGFWAKLEGRNPGGIKDRPALHMVRAARERGELRA  87

Query  85   GAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVG  144
            GA IVEST GTLGLGLALAG VY HPVT+VTDPG+EP++  +L A+GA   +V  PHPVG
Sbjct  88   GARIVESTSGTLGLGLALAGVVYGHPVTVVTDPGIEPLVTGLLAAHGAETVVVDAPHPVG  147

Query  145  GWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGG  204
            GWQQAR+ +V +L+A +PGAW P+QY NPDNV AYR LALELVAQLGRID LV SVGTGG
Sbjct  148  GWQQARRAKVRELLAAHPGAWCPDQYNNPDNVAAYRPLALELVAQLGRIDTLVVSVGTGG  207

Query  205  HSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHW  264
            HSAG+A VLR   P++R++GVDT GSTIFGQPA  RLMRGLGSSI+PRNV Y  FDEVHW
Sbjct  208  HSAGIAGVLRGRFPELRVVGVDTTGSTIFGQPALPRLMRGLGSSIHPRNVAYGLFDEVHW  267

Query  265  VAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTI  324
            VA PEAVWA R+LA + YASGGWSVGAVALVA W A     +  IAAVFPDGPQRY  T+
Sbjct  268  VAAPEAVWAARALAVSRYASGGWSVGAVALVARWLAATGSPEDRIAAVFPDGPQRYVGTV  327

Query  325  YNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            ++D +C  H LLG +PP  PDEIA P + VVTRWTR  TV+DP
Sbjct  328  FDDPWCQAHGLLGHRPPERPDEIAHPGERVVTRWTRCRTVLDP  370


>gi|297153541|gb|ADI03253.1| cysteine synthase A [Streptomyces bingchenggensis BCW-1]
Length=379

 Score =  444 bits (1143),  Expect = 9e-123, Method: Compositional matrix adjust.
 Identities = 239/364 (66%), Positives = 271/364 (75%), Gaps = 5/364 (1%)

Query  6    TRDRYRLLPEGYQVTPGRNRH-PGTMVGNTPVLWIPE-LSGTSDPDRGFWAKLEGFNPGG  63
            TR    L P G    P    H P  +VG+TPVLWI E  + T    RGFWAKLEG NPGG
Sbjct  5    TRTTVPLSPAGLLTNPRIPAHTPAGLVGDTPVLWIGEPFTATG---RGFWAKLEGHNPGG  61

Query  64   MKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPII  123
            +KDR ALYMV  AR RG +  GA IVEST GTLGLGLALAG ++ HPVT+VTDPG+EP++
Sbjct  62   IKDRTALYMVRAARERGQLPCGARIVESTSGTLGLGLALAGAIHGHPVTVVTDPGMEPLM  121

Query  124  ARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLA  183
            + +L A+GA VD+VT PHP GGWQQAR+ RVA+L+A +P AW P+QY NPDNV AY  LA
Sbjct  122  SGLLAAHGAEVDVVTAPHPTGGWQQARRQRVAELLAAHPDAWCPDQYHNPDNVAAYAPLA  181

Query  184  LELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMR  243
             ELVAQLGRID LV SVGTGGHS G+A VLR + P +R+ GVDT GSTIFGQPA+ RLMR
Sbjct  182  HELVAQLGRIDTLVVSVGTGGHSTGIASVLRGYFPHLRVAGVDTTGSTIFGQPAAPRLMR  241

Query  244  GLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNL  303
            GLGSSIYPRNV Y  FDEVHWVA PEAVWA R LA  HYA+GGWSVGAVALVA W AR L
Sbjct  242  GLGSSIYPRNVAYHLFDEVHWVAAPEAVWAARRLARDHYATGGWSVGAVALVARWLARTL  301

Query  304  PADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTT  363
            PA+    AVFPDGPQRY  T+++D YC  H LLG  PP +PD I  P +  VTRWTR T 
Sbjct  302  PAEERTVAVFPDGPQRYVGTVFDDTYCRRHHLLGQLPPDDPDHIDHPGEHTVTRWTRCTR  361

Query  364  VIDP  367
            VIDP
Sbjct  362  VIDP  365


>gi|325003150|ref|ZP_08124262.1| cysteine synthase A [Pseudonocardia sp. P1]
Length=345

 Score =  431 bits (1109),  Expect = 7e-119, Method: Compositional matrix adjust.
 Identities = 217/341 (64%), Positives = 256/341 (76%), Gaps = 3/341 (0%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VG+TP +WI      S   RGFWAKLEG NPGG+KDRPAL+MVE AR RGD+ PGA IV
Sbjct  4    VVGSTPTVWIDAPFAPSG--RGFWAKLEGANPGGIKDRPALHMVEQARERGDLHPGARIV  61

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GTLGLGLALAG  + HPVTLV+DPG+EP++ R+L AYGA V  V      GGWQQA
Sbjct  62   ESTSGTLGLGLALAGIAFGHPVTLVSDPGMEPLMYRLLRAYGAEVVTVQAAATCGGWQQA  121

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R++RVA+++ ++PGAW P+QY NPDNV AY +LA EL +QLG IDVLVCSVGTGGHSAG+
Sbjct  122  RRERVAEILDQHPGAWCPDQYNNPDNVSAYATLADELRSQLGHIDVLVCSVGTGGHSAGI  181

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            +  LR + PD+ ++GVDT+GSTIFGQPA  RLMRGLGSSI+PRNVD+  F EVHWV   E
Sbjct  182  SSALRRYLPDLEVVGVDTVGSTIFGQPARPRLMRGLGSSIHPRNVDHSIFSEVHWVGADE  241

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AV ACR++A   YASGGWSVGAV  VAGW AR  P DT IAA+FPDGPQRYFDT+YND +
Sbjct  242  AVSACRAMACASYASGGWSVGAVGAVAGWLARTRPQDTRIAAIFPDGPQRYFDTVYNDEF  301

Query  330  CNEHELLGGQPPTE-PDEIASPLDAVVTRWTRSTTVIDPTQ  369
            C    +    PP   PD I  P    V RWTR TTV+ P +
Sbjct  302  CEAKGITVSGPPVHAPDVIDRPDAIEVHRWTRCTTVLAPNR  342


>gi|159040088|ref|YP_001539341.1| pyridoxal-5'-phosphate-dependent protein subunit beta [Salinispora 
arenicola CNS-205]
 gi|157918923|gb|ABW00351.1| Pyridoxal-5'-phosphate-dependent protein beta subunit [Salinispora 
arenicola CNS-205]
Length=335

 Score =  428 bits (1101),  Expect = 7e-118, Method: Compositional matrix adjust.
 Identities = 215/320 (68%), Positives = 250/320 (79%), Gaps = 0/320 (0%)

Query  50   RGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRH  109
            RGFWAKLE F+PGG+KDR AL++V  AR RGD++PGA IVEST GT GLGLALA   Y+H
Sbjct  12   RGFWAKLEAFSPGGIKDRSALHLVAQARKRGDLSPGAMIVESTSGTFGLGLALAANAYQH  71

Query  110  PVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQ  169
             +TLVTDPGLEPI+ R+LTA GA + +V +PH  GGWQQAR++RV ++++  PG+W P+Q
Sbjct  72   SLTLVTDPGLEPIMQRLLTASGAAISVVDRPHLQGGWQQARRERVGEILSATPGSWCPDQ  131

Query  170  YGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIG  229
            Y NPD + AY  L LELVAQLGRIDVLVCSVGTGGHSAG    +R + P  RL+GVDTIG
Sbjct  132  YNNPDTLPAYEGLGLELVAQLGRIDVLVCSVGTGGHSAGTFAPIRRYFPHARLVGVDTIG  191

Query  230  STIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSV  289
            STIFGQPA +RLMRGLGSSIYPRNV Y  F EVHWVAP EAVWACR LAA  Y SGGWSV
Sbjct  192  STIFGQPARHRLMRGLGSSIYPRNVQYGWFSEVHWVAPAEAVWACRQLAAHGYVSGGWSV  251

Query  290  GAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIAS  349
            GAVALVA W AR LP DT I AVFPDGPQRY+DT++ND YC  H+LLG +P  +PD I +
Sbjct  252  GAVALVAAWLARTLPFDTRIVAVFPDGPQRYWDTVFNDDYCRRHDLLGIEPAADPDSICA  311

Query  350  PLDAVVTRWTRSTTVIDPTQ  369
            P    V RWTR T ++D  Q
Sbjct  312  PTSHEVHRWTRCTQIVDLGQ  331


>gi|291302174|ref|YP_003513452.1| Pyridoxal-5'-phosphate-dependent protein subunit beta [Stackebrandtia 
nassauensis DSM 44728]
 gi|290571394|gb|ADD44359.1| Pyridoxal-5'-phosphate-dependent protein beta subunit [Stackebrandtia 
nassauensis DSM 44728]
Length=388

 Score =  427 bits (1097),  Expect = 2e-117, Method: Compositional matrix adjust.
 Identities = 216/348 (63%), Positives = 256/348 (74%), Gaps = 7/348 (2%)

Query  23   RNRHPGTM---VGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARAR  79
            R   PG M   VGNTP+L +     T++   G+WAKLEG NPGG+KDR AL++V  AR R
Sbjct  13   RTATPGDMTALVGNTPLLRL----ATAETGHGYWAKLEGANPGGIKDRAALHLVRRARER  68

Query  80   GDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQ  139
            GD+APGA IVES+ GTLGLGLALAG    HPVT+V DPGLEP + R+L AYGA VD+V +
Sbjct  69   GDLAPGAPIVESSSGTLGLGLALAGMASGHPVTVVADPGLEPSLRRLLAAYGAHVDIVAE  128

Query  140  PHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCS  199
            P PVGGWQ+AR+ RVA+L+A  PGAWNP+QY NPDNV AY +L LEL  QL  ID+LVC+
Sbjct  129  PDPVGGWQEARRARVAELIAGSPGAWNPDQYHNPDNVDAYEALGLELAFQLRHIDILVCA  188

Query  200  VGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAF  259
            VGTGGHSAGV  VLR   P  RL+GVD+ GSTIFGQPA  RLMRGLGSSIYPRNV Y  F
Sbjct  189  VGTGGHSAGVFGVLRRLYPHARLVGVDSPGSTIFGQPARPRLMRGLGSSIYPRNVAYDQF  248

Query  260  DEVHWVAPPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQR  319
             EVHWV P  A+ +CR LA   YA+GGWSVGAVALVA W AR  PA   + A+FPDGP R
Sbjct  249  SEVHWVPPAAAIHSCRRLARHSYATGGWSVGAVALVADWLARREPASARVVAIFPDGPHR  308

Query  320  YFDTIYNDAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            Y DT++ND YC +H+LL    PT+P+ + +PL  +   WTR+T V DP
Sbjct  309  YADTVFNDEYCRQHQLLDQPLPTDPETVDNPLGHLSVAWTRTTNVQDP  356


>gi|145594839|ref|YP_001159136.1| pyridoxal-5'-phosphate-dependent enzyme subunit beta [Salinispora 
tropica CNB-440]
 gi|145304176|gb|ABP54758.1| Pyridoxal-5'-phosphate-dependent enzyme, beta subunit [Salinispora 
tropica CNB-440]
Length=335

 Score =  424 bits (1091),  Expect = 9e-117, Method: Compositional matrix adjust.
 Identities = 213/320 (67%), Positives = 249/320 (78%), Gaps = 0/320 (0%)

Query  50   RGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRH  109
            RGFWAKLE F+PGG+KDR AL++V  AR RGD++PGA IVEST GT GLGLALA   Y+H
Sbjct  12   RGFWAKLEAFSPGGIKDRSALHLVAQARKRGDLSPGAMIVESTSGTFGLGLALAANAYQH  71

Query  110  PVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQ  169
             +TLVTDPGLEPI+ R+LTA GA + +V +PH  GGWQQAR++RV ++++  PG+W P+Q
Sbjct  72   SLTLVTDPGLEPIMQRLLTASGAAISVVDRPHLQGGWQQARRERVGEILSATPGSWCPDQ  131

Query  170  YGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIG  229
            Y NPD + AY  L LELVAQLGRIDVLVCSVGTGGHSAG    +R + P  RL+GVDTIG
Sbjct  132  YNNPDTLPAYEGLGLELVAQLGRIDVLVCSVGTGGHSAGTFAPIRRYFPHARLVGVDTIG  191

Query  230  STIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSV  289
            STIFGQPA +RLMRGLGSSIYPRNV Y  F EVHWVAP EAVWACR LA   Y SGGWSV
Sbjct  192  STIFGQPARHRLMRGLGSSIYPRNVQYGWFSEVHWVAPAEAVWACRQLAVHGYVSGGWSV  251

Query  290  GAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEIAS  349
            GAVALVA W AR LP DT I AVFPDGPQRY+DT+++D YC  H+LLG +P  +PD I +
Sbjct  252  GAVALVAAWLARTLPFDTRIVAVFPDGPQRYWDTVFSDDYCRRHDLLGIEPAADPDRICA  311

Query  350  PLDAVVTRWTRSTTVIDPTQ  369
            P    V RWTR T ++D  Q
Sbjct  312  PTSHEVHRWTRCTQIVDLGQ  331


>gi|296165816|ref|ZP_06848316.1| possible cysteine synthase a CysK2 [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295898829|gb|EFG78335.1| possible cysteine synthase a CysK2 [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=226

 Score =  365 bits (937),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 173/226 (77%), Positives = 201/226 (89%), Gaps = 0/226 (0%)

Query  64   MKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPII  123
            MKDRPAL+MVE ARARG++ PGA IVEST G+LGLGLALAG+ Y HPVT+VTD G+EPI+
Sbjct  1    MKDRPALHMVEAARARGELTPGARIVESTSGSLGLGLALAGQAYGHPVTVVTDTGMEPIV  60

Query  124  ARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLA  183
              ML AYGA VD+VT+PHPVGGWQQARKDRVAQ++A +PG+W P+QY NPDN+  Y+SL 
Sbjct  61   RHMLAAYGAQVDLVTEPHPVGGWQQARKDRVAQILAAHPGSWCPDQYSNPDNITGYQSLG  120

Query  184  LELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMR  243
            LEL+ QLG +DVLVCSVGTGGHSAGVARVLR+FNPDM+LIGVDTIGSTIFGQPA+ RLMR
Sbjct  121  LELMDQLGNVDVLVCSVGTGGHSAGVARVLRQFNPDMQLIGVDTIGSTIFGQPATTRLMR  180

Query  244  GLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGWSV  289
            GLGSSI+P N+DY AF+EVHWVAP EAVWA R+LAA ++ASGGWSV
Sbjct  181  GLGSSIHPHNIDYPAFNEVHWVAPHEAVWAARTLAAHNFASGGWSV  226


>gi|238059294|ref|ZP_04604003.1| pyridoxal-phosphate dependent enzyme [Micromonospora sp. ATCC 
39149]
 gi|237881105|gb|EEP69933.1| pyridoxal-phosphate dependent enzyme [Micromonospora sp. ATCC 
39149]
Length=376

 Score =  361 bits (927),  Expect = 9e-98, Method: Compositional matrix adjust.
 Identities = 198/342 (58%), Positives = 240/342 (71%), Gaps = 8/342 (2%)

Query  30   MVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIV  89
            +VG TPV+ +   +    P  GF AK+E  +PGGMK R A+ M+  AR+RG++APGA +V
Sbjct  28   LVGGTPVVLVD--APLPHPQPGFRAKVECLSPGGMKARAAVSMLAGARSRGELAPGAPVV  85

Query  90   ESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQA  149
            EST GT+G+GLA AG+   HPV LV D  LEP +  +L A+GA ++MV  PHPVGGWQQA
Sbjct  86   ESTSGTMGIGLAFAGQALGHPVVLVVDRELEPSMRALLRAHGARLEMVDSPHPVGGWQQA  145

Query  150  RKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGV  209
            R DR+ Q+ A  PGA+ P+QY NPDN   Y  LA E+VAQ+  +D LVCSVGTGGHSAG+
Sbjct  146  RLDRLRQVRAALPGAYWPDQYHNPDNAAGYAGLAEEIVAQVDAVDTLVCSVGTGGHSAGL  205

Query  210  ARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPE  269
            AR LR   P +RL+GVDT+GSTIFGQPA  RLMRGLGSSI+PRNVDY AFDEVHWV P E
Sbjct  206  ARALRRHWPGLRLVGVDTVGSTIFGQPARARLMRGLGSSIHPRNVDYAAFDEVHWVGPAE  265

Query  270  AVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAY  329
            AV  CR LA   + +GGWS GA A VA WAAR  P    + AVFPDGPQRY D+I++D Y
Sbjct  266  AVETCRRLARHAFVTGGWSTGATARVAAWAARTQPG-ARVLAVFPDGPQRYLDSIFDDEY  324

Query  330  CNEHELLGGQPPT--EPDEIASPLDAVVTRWTRSTTVIDPTQ  369
            C    LLG   PT   P EI  P    VTRW+R  T++DP +
Sbjct  325  CALRGLLG---PTRGHPVEICHPRAVEVTRWSRCRTIVDPQR  363


>gi|134102763|ref|YP_001108424.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133915386|emb|CAM05499.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
Length=361

 Score =  361 bits (926),  Expect = 1e-97, Method: Compositional matrix adjust.
 Identities = 187/326 (58%), Positives = 222/326 (69%), Gaps = 1/326 (0%)

Query  47   DPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKV  106
             P  GFWAKLE  + GGMK R AL M+  AR R ++ PGA +VEST GTLGLGLA AG+ 
Sbjct  34   QPHPGFWAKLECVSVGGMKARAALSMLAGARHRAELRPGAPVVESTSGTLGLGLAFAGQA  93

Query  107  YRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWN  166
              HPV LV D  LE  +  +L A+GA +++V +PHPVGGWQQAR DRV +L  E PGA+ 
Sbjct  94   LGHPVVLVVDRELEAGMRALLRAHGARIEVVDRPHPVGGWQQARLDRVRELCRELPGAYW  153

Query  167  PNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVD  226
            P+QY NPDN   Y +L  E+V QLG  DVLVCSVG+GGHSAG  R LR   P +RL+GVD
Sbjct  154  PDQYNNPDNPAGYAALGEEIVHQLGAADVLVCSVGSGGHSAGTIRALRRHWPSIRLVGVD  213

Query  227  TIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGG  286
            T+GSTIFGQPA  R+MRGLGSSI+PRNVDY  FDEVHWV P EAV ACR+LA   + SGG
Sbjct  214  TVGSTIFGQPARPRVMRGLGSSIHPRNVDYAQFDEVHWVGPAEAVQACRTLAERSFVSGG  273

Query  287  WSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDE  346
            WS GAVALV+ W AR + A   +  VFPDGP RY  TI++D +C    L+     T P E
Sbjct  274  WSTGAVALVSAWVAR-VEAGARVVTVFPDGPHRYLHTIFDDDFCRARGLIDTPVATRPVE  332

Query  347  IASPLDAVVTRWTRSTTVIDPTQVVS  372
            IA P    V  W R   V+DP  +V 
Sbjct  333  IAHPRLDEVEGWARCRAVLDPLSLVE  358


>gi|291005937|ref|ZP_06563910.1| putative pyridoxal-phosphate dependent enzyme [Saccharopolyspora 
erythraea NRRL 2338]
Length=353

 Score =  360 bits (924),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 187/326 (58%), Positives = 222/326 (69%), Gaps = 1/326 (0%)

Query  47   DPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKV  106
             P  GFWAKLE  + GGMK R AL M+  AR R ++ PGA +VEST GTLGLGLA AG+ 
Sbjct  26   QPHPGFWAKLECVSVGGMKARAALSMLAGARHRAELRPGAPVVESTSGTLGLGLAFAGQA  85

Query  107  YRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWN  166
              HPV LV D  LE  +  +L A+GA +++V +PHPVGGWQQAR DRV +L  E PGA+ 
Sbjct  86   LGHPVVLVVDRELEAGMRALLRAHGARIEVVDRPHPVGGWQQARLDRVRELCRELPGAYW  145

Query  167  PNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVD  226
            P+QY NPDN   Y +L  E+V QLG  DVLVCSVG+GGHSAG  R LR   P +RL+GVD
Sbjct  146  PDQYNNPDNPAGYAALGEEIVHQLGAADVLVCSVGSGGHSAGTIRALRRHWPSIRLVGVD  205

Query  227  TIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGG  286
            T+GSTIFGQPA  R+MRGLGSSI+PRNVDY  FDEVHWV P EAV ACR+LA   + SGG
Sbjct  206  TVGSTIFGQPARPRVMRGLGSSIHPRNVDYAQFDEVHWVGPAEAVQACRTLAERSFVSGG  265

Query  287  WSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDE  346
            WS GAVALV+ W AR + A   +  VFPDGP RY  TI++D +C    L+     T P E
Sbjct  266  WSTGAVALVSAWVAR-VEAGARVVTVFPDGPHRYLHTIFDDDFCRARGLIDTPVATRPVE  324

Query  347  IASPLDAVVTRWTRSTTVIDPTQVVS  372
            IA P    V  W R   V+DP  +V 
Sbjct  325  IAHPRLDEVEGWARCRAVLDPLSLVE  350


>gi|302538009|ref|ZP_07290351.1| cysteine synthase B [Streptomyces sp. C]
 gi|302446904|gb|EFL18720.1| cysteine synthase B [Streptomyces sp. C]
Length=373

 Score =  349 bits (895),  Expect = 5e-94, Method: Compositional matrix adjust.
 Identities = 184/339 (55%), Positives = 228/339 (68%), Gaps = 3/339 (0%)

Query  29   TMVGNTPVLWIPELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAI  88
            T+VG TP+  I      + P  GFWAKLE    GGMK R A+ M+  AR RG++ PGA +
Sbjct  21   TLVGRTPIARIRTELPYAHP--GFWAKLECLGAGGMKARSAVSMLRGARQRGELRPGATV  78

Query  89   VESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQ  148
            VEST GTLG+GLA AG+   HPV LV D  LEP + ++L AYGA +++V +P   GGWQ 
Sbjct  79   VESTSGTLGVGLAFAGQALGHPVVLVGDRELEPSMRQLLRAYGAQLELVERPATEGGWQA  138

Query  149  ARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAG  208
            AR  R+ +++A  P A+ P+QY NPDN   Y S+A EL  QL  +DVLVCSVGTGGHSAG
Sbjct  139  ARIGRLREVLARIPDAYWPDQYNNPDNAAGYLSMAAELCGQLDHLDVLVCSVGTGGHSAG  198

Query  209  VARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPP  268
            +   LR   P +++IGVD++GS IFGQPA  RLMRGLGSSI+PRNV + AFDEVHWV   
Sbjct  199  LIGPLRRRWPHLKVIGVDSVGSAIFGQPARPRLMRGLGSSIHPRNVVHHAFDEVHWVGAA  258

Query  269  EAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDA  328
            EAV ACR LA T + SGGWS GAVALV+ WA+R + A   +A VFPDGP RY  T+Y+D 
Sbjct  259  EAVDACRRLARTGFVSGGWSTGAVALVSAWASR-VEAGAVVATVFPDGPHRYLGTVYDDD  317

Query  329  YCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            +C+ H L   +    P EIA P       WTR  TV+DP
Sbjct  318  FCHAHGLDRAELARRPLEIAHPHATEAVGWTRCRTVVDP  356


>gi|302540589|ref|ZP_07292931.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
hygroscopicus ATCC 53653]
 gi|302458207|gb|EFL21300.1| pyridoxal-5-phosphate-dependent enzyme, beta subunit [Streptomyces 
himastatinicus ATCC 53653]
Length=363

 Score =  339 bits (869),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 190/341 (56%), Positives = 224/341 (66%), Gaps = 9/341 (2%)

Query  30   MVGNTPVLWIPELSGTSD---PDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGA  86
            ++G TP+  I     T+D   P  GFWAKLEG   GGMK R A+ M+  AR RG++ PGA
Sbjct  17   LLGRTPLARI-----TTDLPCPHPGFWAKLEGLGAGGMKARAAVSMLLGARERGELRPGA  71

Query  87   AIVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGW  146
             +VEST GTLG+GLA AG+   HP+ LV D  LEP + R+L  YGA +++V +P   GGW
Sbjct  72   PVVESTSGTLGVGLAFAGQALGHPIVLVCDTELEPSMRRLLRTYGAQLELVDRPAAEGGW  131

Query  147  QQARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHS  206
            Q AR  R+  L+A  P A+ P+QY NPDN   Y SLA EL AQL  +D+LVCSVGTGGHS
Sbjct  132  QAARLARLRALLALLPDAYWPDQYNNPDNTAGYASLAHELTAQLDHLDILVCSVGTGGHS  191

Query  207  AGVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVA  266
            AG+ R LR   P +RLIGVD  GSTIFGQPA  RLMRGLGSSI+PRNV Y AFDEVHWV 
Sbjct  192  AGIVRPLRGRWPGLRLIGVDATGSTIFGQPARPRLMRGLGSSIHPRNVAYGAFDEVHWVG  251

Query  267  PPEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYN  326
            P EA  +CR LA   + SGGWS GAV LVA WAAR  P    +A VFPDGP RY  T+Y+
Sbjct  252  PAEAADSCRRLARGSFVSGGWSTGAVGLVAAWAARVHPG-AVVATVFPDGPHRYLGTVYD  310

Query  327  DAYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDP  367
            D +   H +      T P EIA P     T W R TTV DP
Sbjct  311  DDFTTAHGVDLATAATRPVEIAHPRAVEATGWARCTTVTDP  351


>gi|323701021|gb|ADY00163.1| hypothetical protein [Streptomyces autolyticus]
Length=363

 Score =  338 bits (868),  Expect = 6e-91, Method: Compositional matrix adjust.
 Identities = 183/320 (58%), Positives = 215/320 (68%), Gaps = 1/320 (0%)

Query  48   PDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAAIVESTGGTLGLGLALAGKVY  107
            P  GFWAKLEG   GGMK R A+ M+  AR RG++ PGA +VEST GTLG+GLA AG+  
Sbjct  33   PHPGFWAKLEGLGAGGMKARAAVSMLLGARERGELRPGAPVVESTSGTLGIGLAFAGQAL  92

Query  108  RHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQQARKDRVAQLMAEYPGAWNP  167
             HP+ LV D  LEP + ++L  YG  +++V +P   GGWQ AR  R+ +L+A  P A+ P
Sbjct  93   GHPIVLVCDTELEPSMRQLLRTYGVRLELVDRPAAEGGWQAARLARLRELLALLPDAYWP  152

Query  168  NQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSAGVARVLREFNPDMRLIGVDT  227
            +QY NPDN   Y SLA EL  QL  +D+LVCSVGTGGHSAG+ R LRE  P +RLIGVD 
Sbjct  153  DQYNNPDNTSGYASLAAELTGQLDHLDILVCSVGTGGHSAGLIRPLRERWPALRLIGVDA  212

Query  228  IGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAPPEAVWACRSLAATHYASGGW  287
             GSTIFGQPA  RLMRGLGSSI+PRNV Y AFDEVHWV P EA   CR+LA   + SGGW
Sbjct  213  TGSTIFGQPARPRLMRGLGSSIHPRNVAYDAFDEVHWVGPAEAAHTCRALARGSFISGGW  272

Query  288  SVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYNDAYCNEHELLGGQPPTEPDEI  347
            S GAV LVA WAAR  P    +A VFPDGP RY  T+Y+D +   H L      T P +I
Sbjct  273  STGAVGLVAAWAARVHPG-AVVATVFPDGPHRYLGTVYDDDFATAHGLDLTTAATRPVQI  331

Query  348  ASPLDAVVTRWTRSTTVIDP  367
            A P  A  T W R TTV DP
Sbjct  332  AHPRAAEATGWVRCTTVTDP  351


>gi|290962492|ref|YP_003493674.1| cysteine synthase [Streptomyces scabiei 87.22]
 gi|260652018|emb|CBG75150.1| putative cysteine synthase [Streptomyces scabiei 87.22]
Length=362

 Score =  326 bits (836),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 188/343 (55%), Positives = 226/343 (66%), Gaps = 5/343 (1%)

Query  29   TMVGNTPVLWI-PELSGTSDPDRGFWAKLEGFNPGGMKDRPALYMVECARARGDIAPGAA  87
            ++VG TP+  I  +L G   P  GFWAKLEG   GGMK R A+ M+  AR RG++ PGA 
Sbjct  17   SLVGRTPLARITADLPG---PQPGFWAKLEGLAAGGMKARAAVSMLLGARERGELLPGAP  73

Query  88   IVESTGGTLGLGLALAGKVYRHPVTLVTDPGLEPIIARMLTAYGAGVDMVTQPHPVGGWQ  147
            +VEST GTLG+GLA AG+   HPV LV D  LEP + ++L ++G  +++V +P  VGGWQ
Sbjct  74   VVESTSGTLGIGLAFAGQALGHPVVLVGDSELEPSMRQLLRSHGVRLELVDRPAAVGGWQ  133

Query  148  QARKDRVAQLMAEYPGAWNPNQYGNPDNVGAYRSLALELVAQLGRIDVLVCSVGTGGHSA  207
             AR  R+  L+A  PGA+ P+QY NPDN   Y SLA EL  QL  +DVLVCSVGTGGHSA
Sbjct  134  AARLTRLRDLLAVLPGAYWPDQYNNPDNTAGYASLAAELAVQLDHVDVLVCSVGTGGHSA  193

Query  208  GVARVLREFNPDMRLIGVDTIGSTIFGQPASNRLMRGLGSSIYPRNVDYRAFDEVHWVAP  267
            G+   LR   P +RL+GVD+ GSTIFGQPA  RLMRGLGSSI+PRNV Y AFDEVHWV P
Sbjct  194  GIIGPLRRHWPALRLVGVDSTGSTIFGQPARPRLMRGLGSSIHPRNVAYDAFDEVHWVGP  253

Query  268  PEAVWACRSLAATHYASGGWSVGAVALVAGWAARNLPADTTIAAVFPDGPQRYFDTIYND  327
             EAV +CR LA   + SGGWS GAVALVA WAAR  P    +A VFPDGP RY  ++Y+D
Sbjct  254  AEAVDSCRRLARGSFVSGGWSTGAVALVAAWAARVHPG-AVVATVFPDGPHRYLGSVYDD  312

Query  328  AYCNEHELLGGQPPTEPDEIASPLDAVVTRWTRSTTVIDPTQV  370
             +   H +        P EI  P  A    W R   V DP QV
Sbjct  313  DFAAAHGIDPASAAVRPVEIPHPGAAEAVGWVRCGRVRDPLQV  355



Lambda     K      H
   0.319    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 709746472050




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40