BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0903c

Length=236
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608043|ref|NP_215418.1|  two component response transcriptio...   458    2e-127
gi|167967698|ref|ZP_02549975.1|  two component system response tr...   452    3e-125
gi|289568870|ref|ZP_06449097.1|  two component system transcripti...   434    4e-120
gi|296169659|ref|ZP_06851277.1|  DNA-binding response regulator [...   426    2e-117
gi|183984600|ref|YP_001852891.1|  two-component response transcri...   425    2e-117
gi|254773908|ref|ZP_05215424.1|  two component response transcrip...   425    3e-117
gi|254822956|ref|ZP_05227957.1|  two component response transcrip...   424    5e-117
gi|240172200|ref|ZP_04750859.1|  two component response transcrip...   421    4e-116
gi|118616126|ref|YP_904458.1|  two component response transcripti...   421    5e-116
gi|41406932|ref|NP_959768.1|  hypothetical protein MAP0834c [Myco...   417    5e-115
gi|15828139|ref|NP_302402.1|  two-component response regulator [M...   414    8e-114
gi|108801411|ref|YP_641608.1|  two component transcriptional regu...   409    2e-112
gi|126437395|ref|YP_001073086.1|  two component transcriptional r...   408    4e-112
gi|118468513|ref|YP_889895.1|  DNA-binding response regulator Prr...   405    2e-111
gi|120405958|ref|YP_955787.1|  two component transcriptional regu...   405    4e-111
gi|145222334|ref|YP_001133012.1|  two component transcriptional r...   401    4e-110
gi|169628053|ref|YP_001701702.1|  transcriptional regulatory prot...   394    8e-108
gi|333989463|ref|YP_004522077.1|  two-component response transcri...   384    8e-105
gi|226308071|ref|YP_002768031.1|  two-component response regulato...   325    3e-87 
gi|229492138|ref|ZP_04385947.1|  DNA-binding response regulator P...   313    1e-83 
gi|226303939|ref|YP_002763897.1|  OmpR family two-component respo...   313    1e-83 
gi|325676260|ref|ZP_08155939.1|  DNA-binding response regulator [...   311    7e-83 
gi|54022631|ref|YP_116873.1|  putative two-component system respo...   300    1e-79 
gi|226364471|ref|YP_002782253.1|  OmpR family two-component respo...   296    2e-78 
gi|333918531|ref|YP_004492112.1|  two component response transcri...   294    7e-78 
gi|111021968|ref|YP_704940.1|  response regulator, two-component ...   294    8e-78 
gi|312138449|ref|YP_004005785.1|  two component system response r...   285    4e-75 
gi|325676168|ref|ZP_08155849.1|  DNA-binding response regulator [...   284    8e-75 
gi|296395434|ref|YP_003660318.1|  transcriptional regulator [Segn...   281    5e-74 
gi|317509412|ref|ZP_07967031.1|  response regulator receiver doma...   279    2e-73 
gi|108797145|ref|YP_637342.1|  two component transcriptional regu...   276    1e-72 
gi|126432768|ref|YP_001068459.1|  two component transcriptional r...   276    2e-72 
gi|118470690|ref|YP_884659.1|  two component response transcripti...   276    2e-72 
gi|120401218|ref|YP_951047.1|  two component transcriptional regu...   268    4e-70 
gi|145221065|ref|YP_001131743.1|  two component transcriptional r...   268    5e-70 
gi|169629014|ref|YP_001702663.1|  putative transcriptional regula...   257    1e-66 
gi|240172708|ref|ZP_04751367.1|  transcriptional regulatory prote...   243    2e-62 
gi|118473019|ref|YP_889726.1|  DNA-binding response regulator [My...   226    2e-57 
gi|336115936|ref|YP_004570702.1|  two-component system response r...   223    1e-56 
gi|296140967|ref|YP_003648210.1|  winged helix family two compone...   223    2e-56 
gi|297625282|ref|YP_003687045.1|  two-component response regulato...   221    7e-56 
gi|269926213|ref|YP_003322836.1|  two component transcriptional r...   221    9e-56 
gi|295837513|ref|ZP_06824446.1|  DNA-binding response regulator [...   219    3e-55 
gi|333025498|ref|ZP_08453562.1|  putative two-component system re...   218    8e-55 
gi|108801265|ref|YP_641462.1|  two component transcriptional regu...   217    9e-55 
gi|29830590|ref|NP_825224.1|  two-component system response regul...   217    1e-54 
gi|158317067|ref|YP_001509575.1|  two component transcriptional r...   217    1e-54 
gi|289770266|ref|ZP_06529644.1|  two-component system response re...   217    1e-54 
gi|302520777|ref|ZP_07273119.1|  phosphate regulon transcriptiona...   217    1e-54 
gi|21222554|ref|NP_628333.1|  two-component systen response regul...   217    1e-54 


>gi|15608043|ref|NP_215418.1| two component response transcriptional regulatory protein PRRA 
[Mycobacterium tuberculosis H37Rv]
 gi|15840322|ref|NP_335359.1| DNA-binding response regulator [Mycobacterium tuberculosis CDC1551]
 gi|31792091|ref|NP_854584.1| two component response transcriptional regulatory protein PRRA 
[Mycobacterium bovis AF2122/97]
 77 more sequence titles
 Length=236

 Score =  458 bits (1179),  Expect = 2e-127, Method: Compositional matrix adjust.
 Identities = 236/236 (100%), Positives = 236/236 (100%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL
Sbjct  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236


>gi|167967698|ref|ZP_02549975.1| two component system response transcriptional regulatory protein 
prrA [Mycobacterium tuberculosis H37Ra]
 gi|61229967|sp|P0A5Z6.1|PRRA_MYCTU RecName: Full=Transcriptional regulatory protein prrA
 gi|61229968|sp|P0A5Z7.1|PRRA_MYCBO RecName: Full=Transcriptional regulatory protein prrA
 gi|90108539|pdb|1YS6|A Chain A, Crystal Structure Of The Response Regulatory Protein 
Prra From Mycobacterium Tuberculosis
 gi|90108540|pdb|1YS6|B Chain B, Crystal Structure Of The Response Regulatory Protein 
Prra From Mycobacterium Tuberculosis
 gi|90108541|pdb|1YS7|A Chain A, Crystal Structure Of The Response Regulator Protein 
Prra Comlexed With Mg2+
 gi|90108542|pdb|1YS7|B Chain B, Crystal Structure Of The Response Regulator Protein 
Prra Comlexed With Mg2+
Length=233

 Score =  452 bits (1162),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 233/233 (100%), Positives = 233/233 (100%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN
Sbjct  1    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  233


>gi|289568870|ref|ZP_06449097.1| two component system transcriptional regulator prrA [Mycobacterium 
tuberculosis T17]
 gi|289542624|gb|EFD46272.1| two component system transcriptional regulator prrA [Mycobacterium 
tuberculosis T17]
Length=236

 Score =  434 bits (1117),  Expect = 4e-120, Method: Compositional matrix adjust.
 Identities = 226/236 (96%), Positives = 227/236 (97%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGGMDTGVT      +   SDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL
Sbjct  1    MGGMDTGVTVELENCLIAHSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236


>gi|296169659|ref|ZP_06851277.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295895656|gb|EFG75352.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=236

 Score =  426 bits (1094),  Expect = 2e-117, Method: Compositional matrix adjust.
 Identities = 231/236 (98%), Positives = 233/236 (99%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGGMDTG TSPRVLVVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVL
Sbjct  1    MGGMDTGGTSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRG+TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGATATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ  236


>gi|183984600|ref|YP_001852891.1| two-component response transcriptional regulatory protein PrrA 
[Mycobacterium marinum M]
 gi|183177926|gb|ACC43036.1| two-component response transcriptional regulatory protein PrrA 
[Mycobacterium marinum M]
Length=236

 Score =  425 bits (1093),  Expect = 2e-117, Method: Compositional matrix adjust.
 Identities = 230/236 (98%), Positives = 232/236 (99%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGGMDTG  SPRVLVVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVL
Sbjct  1    MGGMDTGANSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRG+TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGATATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ  236


>gi|254773908|ref|ZP_05215424.1| two component response transcriptional regulatory protein prra 
[Mycobacterium avium subsp. avium ATCC 25291]
 gi|342860509|ref|ZP_08717160.1| PrrA family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342132164|gb|EGT85405.1| PrrA family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=223

 Score =  425 bits (1092),  Expect = 3e-117, Method: Compositional matrix adjust.
 Identities = 218/223 (98%), Positives = 221/223 (99%), Gaps = 0/223 (0%)

Query  14   LVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVV  73
            +VVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVLDINMPVLDGVSVV
Sbjct  1    MVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVV  60

Query  74   TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTA  133
            TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRG+TA
Sbjct  61   TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGATA  120

Query  134  TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG  193
            TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG
Sbjct  121  TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG  180

Query  194  YDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            YDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  YDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ  223


>gi|254822956|ref|ZP_05227957.1| two component response transcriptional regulatory protein prra 
[Mycobacterium intracellulare ATCC 13950]
Length=223

 Score =  424 bits (1090),  Expect = 5e-117, Method: Compositional matrix adjust.
 Identities = 218/223 (98%), Positives = 221/223 (99%), Gaps = 0/223 (0%)

Query  14   LVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVV  73
            +VVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVLDINMPVLDGVSVV
Sbjct  1    MVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVV  60

Query  74   TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTA  133
            TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRG+TA
Sbjct  61   TALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGATA  120

Query  134  TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG  193
            TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG
Sbjct  121  TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWG  180

Query  194  YDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            YDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  YDFAADTNVVDVFIGYLRRKLEAHGGPRLLHTVRGVGFVLRMQ  223


>gi|240172200|ref|ZP_04750859.1| two component response transcriptional regulatory protein prra 
[Mycobacterium kansasii ATCC 12478]
Length=233

 Score =  421 bits (1083),  Expect = 4e-116, Method: Compositional matrix adjust.
 Identities = 228/233 (98%), Positives = 231/233 (99%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            M+TGV+SPRVLVVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    METGVSSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ  233


>gi|118616126|ref|YP_904458.1| two component response transcriptional regulatory protein PrrA 
[Mycobacterium ulcerans Agy99]
 gi|118568236|gb|ABL02987.1| two component response transcriptional regulatory protein PrrA 
[Mycobacterium ulcerans Agy99]
Length=236

 Score =  421 bits (1081),  Expect = 5e-116, Method: Compositional matrix adjust.
 Identities = 228/236 (97%), Positives = 230/236 (98%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGGMDTG  SPRVLVVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVL
Sbjct  1    MGGMDTGANSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRG+TATSSSE ITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGATATSSSEIITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRM 
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMH  236


>gi|41406932|ref|NP_959768.1| hypothetical protein MAP0834c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118465275|ref|YP_880280.1| PrrA family transcriptional regulator [Mycobacterium avium 104]
 gi|41395282|gb|AAS03151.1| hypothetical protein MAP_0834c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118166562|gb|ABK67459.1| two component response transcriptional regulatory protein prra 
[Mycobacterium avium 104]
 gi|336461286|gb|EGO40160.1| response regulator with CheY-like receiver domain-containing 
protein [Mycobacterium avium subsp. paratuberculosis S397]
Length=233

 Score =  417 bits (1073),  Expect = 5e-115, Method: Compositional matrix adjust.
 Identities = 226/233 (97%), Positives = 229/233 (99%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MDT  +SPRVLVVDDDSDVLASLERGLRLSGFEV+TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    MDTAASSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRG+TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGATATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA GGPRLLHTVRGVGFVLRMQ
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ  233


>gi|15828139|ref|NP_302402.1| two-component response regulator [Mycobacterium leprae TN]
 gi|221230616|ref|YP_002504032.1| two-component response regulator [Mycobacterium leprae Br4923]
 gi|34098418|sp|Q50136.2|PRRA_MYCLE RecName: Full=Transcriptional regulatory protein prrA
 gi|2440114|emb|CAB16701.1| two-component regulator [Mycobacterium leprae]
 gi|13093693|emb|CAC31078.1| two-component response regulator [Mycobacterium leprae]
 gi|219933723|emb|CAR72220.1| two-component response regulator [Mycobacterium leprae Br4923]
Length=233

 Score =  414 bits (1063),  Expect = 8e-114, Method: Compositional matrix adjust.
 Identities = 223/233 (96%), Positives = 228/233 (98%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MDTGV+SPRVLVVDDDSDVLASLERGLRLSGFEV+TA+DGAEALR+ATE RPDAIVLDIN
Sbjct  1    MDTGVSSPRVLVVDDDSDVLASLERGLRLSGFEVSTAIDGAEALRNATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRG+TATSSSETI VGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKT VLS
Sbjct  121  ALLRRRGATATSSSETIAVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTTVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA  GPRLLHTVRGVGFVLRMQ
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANSGPRLLHTVRGVGFVLRMQ  233


>gi|108801411|ref|YP_641608.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119870564|ref|YP_940516.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|108771830|gb|ABG10552.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119696653|gb|ABL93726.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
Length=233

 Score =  409 bits (1051),  Expect = 2e-112, Method: Compositional matrix adjust.
 Identities = 222/233 (96%), Positives = 226/233 (97%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MD+GV SPRVLVVDDD DVLASLERGLRLSGF+V+TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    MDSGVGSPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEALRSATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGS+AT SSETI VGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGSSATFSSETIQVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGG PRLLHTVRGVGFVLR Q
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ  233


>gi|126437395|ref|YP_001073086.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|126237195|gb|ABO00596.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=233

 Score =  408 bits (1048),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 221/233 (95%), Positives = 225/233 (97%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MD+GV SPRVLVVDDD DVLASLERGLRLSGF+V+TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    MDSGVGSPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEALRSATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGS+AT SSETI VGPLEVDIPGRRARVNG DVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGSSATFSSETIQVGPLEVDIPGRRARVNGADVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGG PRLLHTVRGVGFVLR Q
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ  233


>gi|118468513|ref|YP_889895.1| DNA-binding response regulator PrrA [Mycobacterium smegmatis 
str. MC2 155]
 gi|118169800|gb|ABK70696.1| DNA-binding response regulator PrrA [Mycobacterium smegmatis 
str. MC2 155]
Length=236

 Score =  405 bits (1042),  Expect = 2e-111, Method: Compositional matrix adjust.
 Identities = 220/236 (94%), Positives = 225/236 (96%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            M    +G+ SPRVLVVDDD DVLASLERGLRLSGF+V+TAVDGAEALRSATE RPDAIVL
Sbjct  1    MDSTTSGMASPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEALRSATETRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RVKALLRRRGS+AT SSETI VGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVKALLRRRGSSATFSSETIQVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGG PRLLHTVRGVGFVLR Q
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ  236


>gi|120405958|ref|YP_955787.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958776|gb|ABM15781.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=233

 Score =  405 bits (1040),  Expect = 4e-111, Method: Compositional matrix adjust.
 Identities = 220/233 (95%), Positives = 224/233 (97%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MD+G  SP+VLVVDDD DVLASLERGLRLSGF+V TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    MDSGAGSPKVLVVDDDPDVLASLERGLRLSGFDVYTAVDGAEALRSATETRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGSTAT SSETITVGPLEVDIPGRRARV+GVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGSTATFSSETITVGPLEVDIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA G PRLLHTVRGVGFVLR Q
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ  233


>gi|145222334|ref|YP_001133012.1| two component transcriptional regulator [Mycobacterium gilvum 
PYR-GCK]
 gi|315442767|ref|YP_004075646.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
 gi|145214820|gb|ABP44224.1| two component transcriptional regulator, winged helix family 
[Mycobacterium gilvum PYR-GCK]
 gi|315261070|gb|ADT97811.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
Length=231

 Score =  401 bits (1031),  Expect = 4e-110, Method: Compositional matrix adjust.
 Identities = 221/233 (95%), Positives = 224/233 (97%), Gaps = 2/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MD+G  SPRVLVVDDD DVLASLERGLRLSGF+V TAVDGAEALRSATE RPDAIVLDIN
Sbjct  1    MDSG--SPRVLVVDDDPDVLASLERGLRLSGFDVFTAVDGAEALRSATETRPDAIVLDIN  58

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK
Sbjct  59   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  118

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRGSTAT SSETITVGPLEVDIPGRRARV+GVDVDLTKREFDLLAVLAEHKTAVLS
Sbjct  119  ALLRRRGSTATFSSETITVGPLEVDIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLS  178

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEA G PRLLHTVRGVGFVLR Q
Sbjct  179  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ  231


>gi|169628053|ref|YP_001701702.1| transcriptional regulatory protein PrrA [Mycobacterium abscessus 
ATCC 19977]
 gi|169240020|emb|CAM61048.1| Probable transcriptional regulatory protein PrrA [Mycobacterium 
abscessus]
Length=233

 Score =  394 bits (1011),  Expect = 8e-108, Method: Compositional matrix adjust.
 Identities = 214/233 (92%), Positives = 222/233 (96%), Gaps = 0/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            M  G  SPRVLVVDDD+DVLASLERGLRLSGFEV TA DGAEALR ATE+RPDAIVLDIN
Sbjct  1    MVDGQGSPRVLVVDDDADVLASLERGLRLSGFEVNTASDGAEALRCATEHRPDAIVLDIN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAMDNDVPVCVLSAR+SVDDRVAGLEAGADDYL KPFVLAELVARVK
Sbjct  61   MPVLDGVSVVTALRAMDNDVPVCVLSARTSVDDRVAGLEAGADDYLTKPFVLAELVARVK  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRRRG+ ATSS+ETITVGPLEV+IPGRRAR+NGV+VDLTKREFDLLAVLAEHKTAVLS
Sbjct  121  ALLRRRGAVATSSTETITVGPLEVEIPGRRARINGVEVDLTKREFDLLAVLAEHKTAVLS  180

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGG PRLLHTVRGVGFVLR Q
Sbjct  181  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRSQ  233


>gi|333989463|ref|YP_004522077.1| two-component response transcriptional regulatory protein PrrA 
[Mycobacterium sp. JDM601]
 gi|333485431|gb|AEF34823.1| two-component response transcriptional regulatory protein PrrA 
[Mycobacterium sp. JDM601]
Length=236

 Score =  384 bits (985),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 216/236 (92%), Positives = 220/236 (94%), Gaps = 0/236 (0%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            M        SPRVLVVDDDSDVLASLERGLRLSGFEVATA DGAEALRSA E RPDAIVL
Sbjct  1    MNNPANAAASPRVLVVDDDSDVLASLERGLRLSGFEVATAADGAEALRSAKETRPDAIVL  60

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            DINMPVLDGVSVVTALRAM +DVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA
Sbjct  61   DINMPVLDGVSVVTALRAMGDDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120

Query  121  RVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            RV+A+LRRRGS A+SSSETITVGPLEVDIPGRRARV GVDVDLTKREFDLLAVLAEHKTA
Sbjct  121  RVRAMLRRRGSAASSSSETITVGPLEVDIPGRRARVKGVDVDLTKREFDLLAVLAEHKTA  180

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGG PRLLHTVRGVGFVLR Q
Sbjct  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ  236


>gi|226308071|ref|YP_002768031.1| two-component response regulator PrrA [Rhodococcus erythropolis 
PR4]
 gi|229488493|ref|ZP_04382359.1| DNA-binding response regulator PrrA [Rhodococcus erythropolis 
SK121]
 gi|226187188|dbj|BAH35292.1| two-component response regulator PrrA [Rhodococcus erythropolis 
PR4]
 gi|229323997|gb|EEN89752.1| DNA-binding response regulator PrrA [Rhodococcus erythropolis 
SK121]
Length=234

 Score =  325 bits (833),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 164/227 (73%), Positives = 193/227 (86%), Gaps = 3/227 (1%)

Query  11   PRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGV  70
            P++LVVDDD+DVL SLERGLRLSGF V TAVDGA+ALR  ++ RPDA+VLDINMPVLDG 
Sbjct  5    PKILVVDDDADVLTSLERGLRLSGFTVLTAVDGADALRVISDKRPDAVVLDINMPVLDGT  64

Query  71   SVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRG  130
             VVTALRA  N++P+CVLSAR+SVDDR+AGLE+GADDY+VKPFVLAELVAR++A+LRR  
Sbjct  65   GVVTALRAAGNEIPICVLSARNSVDDRIAGLESGADDYMVKPFVLAELVARIRAMLRRSN  124

Query  131  STATSSSE---TITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQL  187
            + A   SE   T+ VG L++D+ GRR RV+G +V LTKREF+LL VLA +   VL+R +L
Sbjct  125  TPAGDHSEGTNTLRVGNLDIDLSGRRVRVDGKEVPLTKREFELLEVLAHNSGIVLTRERL  184

Query  188  LELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            LELVWGYDF ADTNVVDVFIGYLRRK E+GG PRLLHTVRGVGFVLR
Sbjct  185  LELVWGYDFVADTNVVDVFIGYLRRKFESGGSPRLLHTVRGVGFVLR  231


>gi|229492138|ref|ZP_04385947.1| DNA-binding response regulator PrrA [Rhodococcus erythropolis 
SK121]
 gi|229320926|gb|EEN86738.1| DNA-binding response regulator PrrA [Rhodococcus erythropolis 
SK121]
Length=234

 Score =  313 bits (803),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 160/228 (71%), Positives = 184/228 (81%), Gaps = 0/228 (0%)

Query  9    TSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLD  68
            T  R+L+VDDD+ VL SLERGLRLSGF+ ATAVDG  AL S  +  P A+VLD+NMP LD
Sbjct  6    TRERILIVDDDAKVLNSLERGLRLSGFDTATAVDGRSALSSVNKQCPAALVLDVNMPGLD  65

Query  69   GVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRR  128
            GV VVTALRA+ N+VP+CVLSARSSV DR+AGLEAGADDYL KPF LAELVAR++ALLRR
Sbjct  66   GVGVVTALRAIGNEVPICVLSARSSVGDRIAGLEAGADDYLTKPFELAELVARLRALLRR  125

Query  129  RGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLL  188
                  S    ITVGPL VD+ G RA ++G  ++LTKREFDLL+VLAEH   VLSRAQLL
Sbjct  126  TTRATPSVDHPITVGPLTVDLRGHRAHIDGRRIELTKREFDLLSVLAEHAGVVLSRAQLL  185

Query  189  ELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
             LVWGYDFAADTNVVDVF+ YLR+KLE  G PR++HTVRGVGFVLR +
Sbjct  186  RLVWGYDFAADTNVVDVFVTYLRKKLEVDGAPRVIHTVRGVGFVLRAE  233


>gi|226303939|ref|YP_002763897.1| OmpR family two-component response regulator [Rhodococcus erythropolis 
PR4]
 gi|226183054|dbj|BAH31158.1| probable OmpR family two-component response regulator [Rhodococcus 
erythropolis PR4]
Length=231

 Score =  313 bits (802),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 160/228 (71%), Positives = 184/228 (81%), Gaps = 0/228 (0%)

Query  9    TSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLD  68
            T  R+L+VDDD+ VL SLERGLRLSGF+ ATAVDG  AL S  +  P A+VLD+NMP LD
Sbjct  3    TRERILIVDDDAKVLNSLERGLRLSGFDTATAVDGRSALSSVNKQCPAALVLDVNMPGLD  62

Query  69   GVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRR  128
            GV VVTALRA+ N+VP+CVLSARSSV DR+AGLEAGADDYL KPF LAELVAR++ALLRR
Sbjct  63   GVGVVTALRAIGNEVPICVLSARSSVGDRIAGLEAGADDYLTKPFELAELVARLRALLRR  122

Query  129  RGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLL  188
                  S    ITVGPL VD+ G RA ++G  ++LTKREFDLL+VLAEH   VLSRAQLL
Sbjct  123  TTRATPSVDHPITVGPLTVDLRGHRAHIDGGRIELTKREFDLLSVLAEHAGVVLSRAQLL  182

Query  189  ELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
             LVWGYDFAADTNVVDVF+ YLR+KLE  G PR++HTVRGVGFVLR +
Sbjct  183  RLVWGYDFAADTNVVDVFVTYLRKKLEVDGAPRVIHTVRGVGFVLRAE  230


>gi|325676260|ref|ZP_08155939.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
 gi|325552821|gb|EGD22504.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
Length=233

 Score =  311 bits (796),  Expect = 7e-83, Method: Compositional matrix adjust.
 Identities = 172/233 (74%), Positives = 193/233 (83%), Gaps = 1/233 (0%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            MD    S R+L+VDDD  VL+SL RGLRLSGFE+ TA DGA ALR+ +E+RPDAIVLD+N
Sbjct  1    MDAVTDSARILLVDDDPKVLSSLTRGLRLSGFELDTADDGASALRAVSESRPDAIVLDVN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MPVLDGVSVVTALRAM NDVP+CVLSARS+V DR+AGLEAGADDYL KPF L ELVAR++
Sbjct  61   MPVLDGVSVVTALRAMGNDVPICVLSARSTVGDRIAGLEAGADDYLTKPFELGELVARLR  120

Query  124  ALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLS  183
            ALLRR   T   +  T+TVGPLEVD+PGRR  + G  +DLTKREFDLL VLAE+   VLS
Sbjct  121  ALLRRAPRTPAPAG-TVTVGPLEVDLPGRRVHMGGERIDLTKREFDLLEVLAENAGIVLS  179

Query  184  RAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            R +LLELVWGYDF ADTNVVDVF  YLRRKLEAGG PR+LHTVRGVGFVLR Q
Sbjct  180  RVRLLELVWGYDFDADTNVVDVFATYLRRKLEAGGRPRVLHTVRGVGFVLREQ  232


>gi|54022631|ref|YP_116873.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
 gi|54014139|dbj|BAD55509.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
Length=238

 Score =  300 bits (767),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 171/236 (73%), Positives = 196/236 (84%), Gaps = 3/236 (1%)

Query  1    MGGMDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVL  60
            MGG+ T  T P VLVVDDD DVLAS+ERGLRLSGF V  A DGA ALRS   + PDA+VL
Sbjct  1    MGGVSTSPT-PTVLVVDDDEDVLASVERGLRLSGFHVLVARDGAAALRSVNADCPDAVVL  59

Query  61   DINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVA  120
            D+NMPVLDG  VVTALRA+ NDVP+CVLSAR+SVDDR++GLE+GADDYLVKPFVLAELVA
Sbjct  60   DMNMPVLDGAGVVTALRALGNDVPICVLSARASVDDRISGLESGADDYLVKPFVLAELVA  119

Query  121  RVKALLRRR--GSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHK  178
            R+KALLRRR     A ++   ITVGPLEVD  G RA ++G +++LTKREF+LL+ LA + 
Sbjct  120  RIKALLRRRTDAPAAAATPGAITVGPLEVDEAGYRALLHGREIELTKREFELLSTLARNA  179

Query  179  TAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
              VLSR +LLELVWGYDFAADTNVVDVF+GYLRRKLEA G PRLLHT+RGVGFVLR
Sbjct  180  GVVLSRERLLELVWGYDFAADTNVVDVFVGYLRRKLEADGTPRLLHTIRGVGFVLR  235


>gi|226364471|ref|YP_002782253.1| OmpR family two-component response regulator [Rhodococcus opacus 
B4]
 gi|226242960|dbj|BAH53308.1| OmpR family two-component response regulator [Rhodococcus opacus 
B4]
Length=238

 Score =  296 bits (758),  Expect = 2e-78, Method: Compositional matrix adjust.
 Identities = 148/215 (69%), Positives = 176/215 (82%), Gaps = 5/215 (2%)

Query  25   SLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVP  84
            SLERGLRLSGF V TAVDGA+ALR  +E RPDA+VLD+NMPV+DG  VVTALRAM ND+P
Sbjct  21   SLERGLRLSGFTVLTAVDGADALRVVSEQRPDAMVLDMNMPVIDGTGVVTALRAMSNDIP  80

Query  85   VCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSET-----  139
            +CVLSAR +VDDR++GLE+GADDYLVKPFVLAEL+AR++A+LRR G+T  + +++     
Sbjct  81   ICVLSARDTVDDRISGLESGADDYLVKPFVLAELIARIRAMLRRHGTTTAAPADSQATPP  140

Query  140  ITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAAD  199
            I VG LE+    RR  + G +V LTKREF+LL VLA +   VLSR +LLELVWGYDF AD
Sbjct  141  IRVGALEIRTSARRVFMAGEEVTLTKREFELLEVLARNVGIVLSRERLLELVWGYDFVAD  200

Query  200  TNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            TNVVDVF+GYLRRK E GG PR+LHTVRGVGFVLR
Sbjct  201  TNVVDVFVGYLRRKFEVGGQPRILHTVRGVGFVLR  235


>gi|333918531|ref|YP_004492112.1| two component response transcriptional regulator prra [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333480752|gb|AEF39312.1| two component response transcriptional regulatory protein prra 
[Amycolicicoccus subflavus DQS3-9A1]
Length=231

 Score =  294 bits (753),  Expect = 7e-78, Method: Compositional matrix adjust.
 Identities = 145/214 (68%), Positives = 174/214 (82%), Gaps = 1/214 (0%)

Query  24   ASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDV  83
            +SL+RGLRLSGF+V TA DG  ALR+     PDAIVLD+ MP LDGVSVVTALRAM +D+
Sbjct  18   SSLKRGLRLSGFDVMTAEDGESALRTIRTQEPDAIVLDVTMPRLDGVSVVTALRAMGSDI  77

Query  84   PVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSS-ETITV  142
            P+CVLSARSSVDDR+AGLEAGADDYL KPF L EL+ARV+A+LRRR   + S   E +T 
Sbjct  78   PICVLSARSSVDDRIAGLEAGADDYLTKPFALGELIARVRAMLRRRPDQSPSPKRELLTA  137

Query  143  GPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNV  202
            G LE+D+  RRA + G ++DLTKREF+LL  L +H+ AVLSR QLLE+VWGYDF ADTNV
Sbjct  138  GQLEIDVAARRAVIAGTELDLTKREFELLTTLVQHRDAVLSRRQLLEIVWGYDFDADTNV  197

Query  203  VDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VDVF+GYLR+K+EA G  R+LHTVRGVGF+LR +
Sbjct  198  VDVFVGYLRKKMEADGARRMLHTVRGVGFILRTR  231


>gi|111021968|ref|YP_704940.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|110821498|gb|ABG96782.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
Length=238

 Score =  294 bits (752),  Expect = 8e-78, Method: Compositional matrix adjust.
 Identities = 148/215 (69%), Positives = 177/215 (83%), Gaps = 5/215 (2%)

Query  25   SLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVP  84
            SLERGLRLSGF V TAVDGA+ALR  +E RPDA+VLD+NMPV+DG  VVTALRAM+ND+P
Sbjct  21   SLERGLRLSGFTVLTAVDGADALRVVSERRPDAMVLDMNMPVIDGTGVVTALRAMNNDIP  80

Query  85   VCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTA-----TSSSET  139
            +CVLSAR +VDDR++GLE+GADDYLVKPFVLAEL+AR++A+LRR G+TA     + ++  
Sbjct  81   ICVLSARDTVDDRISGLESGADDYLVKPFVLAELIARIRAMLRRHGTTAAAPAGSPATPP  140

Query  140  ITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAAD  199
            I VG LE+    RR  + G +V LTKREF+LL VLA +   VLSR +LLELVWGYDF AD
Sbjct  141  IRVGALEIRTSARRVFMAGEEVTLTKREFELLEVLARNVGIVLSRERLLELVWGYDFVAD  200

Query  200  TNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            TNVVDVF+GYLRRK E GG PR+L+TVRGVGFVLR
Sbjct  201  TNVVDVFVGYLRRKFEVGGQPRILYTVRGVGFVLR  235


>gi|312138449|ref|YP_004005785.1| two component system response regulator [Rhodococcus equi 103S]
 gi|311887788|emb|CBH47100.1| two component system response regulator [Rhodococcus equi 103S]
Length=231

 Score =  285 bits (729),  Expect = 4e-75, Method: Compositional matrix adjust.
 Identities = 148/213 (70%), Positives = 169/213 (80%), Gaps = 2/213 (0%)

Query  24   ASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDV  83
            ASLERGLRLSGF V TA DGA AL+   E  PDA+VLD+NMPVLDG  VVTALR   N+V
Sbjct  16   ASLERGLRLSGFTVLTASDGAVALKVVAEAAPDAVVLDMNMPVLDGTGVVTALRRAGNEV  75

Query  84   PVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--GSTATSSSETIT  141
            P+CVLSARSSVDDR+AGLE+GADDYLVKPFVLAELVAR++A+LRRR     AT +   I 
Sbjct  76   PICVLSARSSVDDRIAGLESGADDYLVKPFVLAELVARIRAMLRRRSVAVAATDTDPPIV  135

Query  142  VGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTN  201
            VGPL VD+ GRR  +   ++ LTKREF+L  VLA +   VLSR +LL+LVWGYDF ADTN
Sbjct  136  VGPLSVDLAGRRVWLGDTEITLTKREFELTEVLARNAGVVLSRERLLDLVWGYDFVADTN  195

Query  202  VVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            VVDVF+GYLRRK E  G PRL+HTVRGVGFVLR
Sbjct  196  VVDVFVGYLRRKFEIDGTPRLVHTVRGVGFVLR  228


>gi|325676168|ref|ZP_08155849.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
 gi|325553078|gb|EGD22759.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
Length=244

 Score =  284 bits (726),  Expect = 8e-75, Method: Compositional matrix adjust.
 Identities = 148/213 (70%), Positives = 169/213 (80%), Gaps = 2/213 (0%)

Query  24   ASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDV  83
            ASLERGLRLSGF V TA DGA ALR   +  PDA+VLD+NMPVLDG  VVTALR   N+V
Sbjct  29   ASLERGLRLSGFTVLTASDGAVALRVVADAAPDAVVLDMNMPVLDGTGVVTALRRAGNEV  88

Query  84   PVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--GSTATSSSETIT  141
            P+CVLSARSSVDDR+AGLE+GADDYLVKPFVLAELVAR++A+LRRR     AT +   I 
Sbjct  89   PICVLSARSSVDDRIAGLESGADDYLVKPFVLAELVARIRAMLRRRSVAVAATDTDPPIV  148

Query  142  VGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTN  201
            VGPL VD+ GRR  +   ++ LTKREF+L  VLA +   VLSR +LL+LVWGYDF ADTN
Sbjct  149  VGPLSVDLAGRRVWLGDTEIALTKREFELTEVLARNAGVVLSRERLLDLVWGYDFVADTN  208

Query  202  VVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            VVDVF+GYLRRK E  G PRL+HTVRGVGFVLR
Sbjct  209  VVDVFVGYLRRKFEIDGTPRLVHTVRGVGFVLR  241


>gi|296395434|ref|YP_003660318.1| transcriptional regulator [Segniliparus rotundus DSM 44985]
 gi|296182581|gb|ADG99487.1| two component transcriptional regulator, winged helix family 
[Segniliparus rotundus DSM 44985]
Length=238

 Score =  281 bits (720),  Expect = 5e-74, Method: Compositional matrix adjust.
 Identities = 159/235 (68%), Positives = 184/235 (79%), Gaps = 4/235 (1%)

Query  4    MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDIN  63
            M+T   SP VLVVDDD DVL+SL+RGLRLSGF V TA +GA AL +  +  PDA++LD+N
Sbjct  1    METSAGSPTVLVVDDDPDVLSSLQRGLRLSGFSVVTADNGAAALSAVHQQHPDALILDMN  60

Query  64   MPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVK  123
            MP LDGVSVVTALRAM +D+P+CVLSARSSV DR+ GLEAGADDYL KPFVL EL+ARVK
Sbjct  61   MPGLDGVSVVTALRAMGDDIPICVLSARSSVGDRIEGLEAGADDYLTKPFVLGELIARVK  120

Query  124  ALLRRRGSTA----TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKT  179
            ALLRR  +T+    T     I V  L VDIPGRR  V+   ++LTKREF+LLA LAE+  
Sbjct  121  ALLRRPSTTSRAAPTVEYGVIHVDYLGVDIPGRRVTVDDESIELTKREFELLAALAENTG  180

Query  180  AVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
             VLSR +LLE VWGYDFAADTNVVDVF+GYLR+KLE  G  RL+HTVRG GFVLR
Sbjct  181  VVLSRTELLERVWGYDFAADTNVVDVFVGYLRKKLELKGRHRLIHTVRGYGFVLR  235


>gi|317509412|ref|ZP_07967031.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
 gi|316252335|gb|EFV11786.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
Length=239

 Score =  279 bits (714),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 160/234 (69%), Positives = 183/234 (79%), Gaps = 4/234 (1%)

Query  5    DTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINM  64
            +T  +SP VLVVDDD DVL+SL+RGLRLSGF V TA +GA AL +  +  PDA++LD+NM
Sbjct  3    NTPTSSPTVLVVDDDPDVLSSLQRGLRLSGFSVVTADNGAAALSAVHQQHPDALILDMNM  62

Query  65   PVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKA  124
            P LDGVSVVTALRAM +D+P+CVLSARSSV DR+ GLEAGADDYL KPFVL ELVARVKA
Sbjct  63   PGLDGVSVVTALRAMGDDIPICVLSARSSVGDRIEGLEAGADDYLTKPFVLGELVARVKA  122

Query  125  LLRRRGST----ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTA  180
            LLRR  +T     T     I V  L VDIPGRR  V+   V+LTKREF+LLA LAE+   
Sbjct  123  LLRRPSTTNRPAPTVEFGVIHVDYLSVDIPGRRVTVDDEPVELTKREFELLAALAENTGV  182

Query  181  VLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            VLSR +LLE VWGYDFAADTNVVDVF+GYLR+KLE  G  RL+HTVRG GFVLR
Sbjct  183  VLSRTELLERVWGYDFAADTNVVDVFVGYLRKKLELKGRHRLIHTVRGYGFVLR  236


>gi|108797145|ref|YP_637342.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119866230|ref|YP_936182.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|108767564|gb|ABG06286.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119692319|gb|ABL89392.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
Length=243

 Score =  276 bits (707),  Expect = 1e-72, Method: Compositional matrix adjust.
 Identities = 146/222 (66%), Positives = 172/222 (78%), Gaps = 1/222 (0%)

Query  13   VLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSV  72
            VL+VDDD DV  S+ RGLR SGF+V  A +G EALR  +    DA+VLD+ MP LDGV+V
Sbjct  20   VLMVDDDPDVRTSVARGLRHSGFDVRVAANGKEALRLLSAESHDALVLDVQMPELDGVAV  79

Query  73   VTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGST  132
            VTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR+ ALL RR   
Sbjct  80   VTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLHALL-RRAHH  138

Query  133  ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVW  192
            +   S+T+TVGPL +D   R   V+G  VDLTKREFDLLAVLAE+   VLSR +LLELVW
Sbjct  139  SDRPSDTMTVGPLTIDTARRLVFVDGERVDLTKREFDLLAVLAENNGVVLSRQRLLELVW  198

Query  193  GYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            GYDF  DTNV DVFI YLRRKLE  G PR++HTVRG+G+VLR
Sbjct  199  GYDFDVDTNVADVFISYLRRKLERDGLPRVIHTVRGIGYVLR  240


>gi|126432768|ref|YP_001068459.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|126232568|gb|ABN95968.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=243

 Score =  276 bits (707),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 146/222 (66%), Positives = 172/222 (78%), Gaps = 1/222 (0%)

Query  13   VLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSV  72
            VL+VDDD DV  S+ RGLR SGF+V  A +G EALR  +    DA+VLD+ MP LDGV+V
Sbjct  20   VLMVDDDPDVRTSVARGLRHSGFDVRVAANGKEALRLLSAESHDALVLDVQMPELDGVAV  79

Query  73   VTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGST  132
            VTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR+ ALL RR   
Sbjct  80   VTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLHALL-RRAHH  138

Query  133  ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVW  192
            +   S+T+TVGPL +D   R   V+G  VDLTKREFDLLAVLAE+   VLSR +LLELVW
Sbjct  139  SDRPSDTMTVGPLTIDTARRLVFVDGERVDLTKREFDLLAVLAENNGVVLSRQRLLELVW  198

Query  193  GYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            GYDF  DTNV DVFI YLRRKLE  G PR++HTVRG+G+VLR
Sbjct  199  GYDFDVDTNVADVFISYLRRKLERDGLPRVIHTVRGIGYVLR  240


>gi|118470690|ref|YP_884659.1| two component response transcriptional regulatory protein prra 
[Mycobacterium smegmatis str. MC2 155]
 gi|118171977|gb|ABK72873.1| two component response transcriptional regulatory protein prra 
[Mycobacterium smegmatis str. MC2 155]
Length=246

 Score =  276 bits (706),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 146/224 (66%), Positives = 172/224 (77%), Gaps = 1/224 (0%)

Query  13   VLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSV  72
            VL+VDDD DV  S+ RGLR SGF+V  A  G EALR  +    DA+VLD+ MP LDGV+V
Sbjct  23   VLMVDDDPDVRTSVARGLRHSGFDVRVAASGKEALRLLSTESHDALVLDVQMPELDGVAV  82

Query  73   VTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGST  132
            VTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR+ ALL RR S 
Sbjct  83   VTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLHALL-RRASH  141

Query  133  ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVW  192
                S+T+TVGP+ +D   R   V+G  VDLTKREFDLLAVLAE+   VLSR +LLELVW
Sbjct  142  TEQPSDTMTVGPVTIDTARRLVFVSGERVDLTKREFDLLAVLAENAGVVLSRQRLLELVW  201

Query  193  GYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            GYDF  DTNV DVFI YLRRKLE  G PR++HTVRG+G+VLR +
Sbjct  202  GYDFDVDTNVADVFISYLRRKLERDGVPRVIHTVRGIGYVLREE  245


>gi|120401218|ref|YP_951047.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954036|gb|ABM11041.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=244

 Score =  268 bits (686),  Expect = 4e-70, Method: Compositional matrix adjust.
 Identities = 142/224 (64%), Positives = 170/224 (76%), Gaps = 1/224 (0%)

Query  13   VLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSV  72
            VL+VDDD DV  S+ RGLR SGF+V  A  G EALR  +    DA+VLD+ MP LDGV+V
Sbjct  21   VLMVDDDPDVRTSVARGLRHSGFDVRVAATGKEALRLLSSESHDALVLDVQMPELDGVAV  80

Query  73   VTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGST  132
            VTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR+ ALL RR   
Sbjct  81   VTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLHALL-RRAHH  139

Query  133  ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVW  192
            +  +S+T+TVG L +D   R   V G  V+LTKREFDLLA LAE+   VLSR +LLELVW
Sbjct  140  SDPTSDTMTVGSLTIDTARRLVFVAGERVELTKREFDLLAALAENAGVVLSRQRLLELVW  199

Query  193  GYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            GYDF  DTNV DVF+ YLRRKLE  G PR++HTVRG+G+VLR +
Sbjct  200  GYDFDVDTNVADVFVSYLRRKLEREGLPRVIHTVRGIGYVLRAE  243


>gi|145221065|ref|YP_001131743.1| two component transcriptional regulator [Mycobacterium gilvum 
PYR-GCK]
 gi|315441964|ref|YP_004074843.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
 gi|145213551|gb|ABP42955.1| two component transcriptional regulator, winged helix family 
[Mycobacterium gilvum PYR-GCK]
 gi|315260267|gb|ADT97008.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
Length=248

 Score =  268 bits (685),  Expect = 5e-70, Method: Compositional matrix adjust.
 Identities = 142/224 (64%), Positives = 170/224 (76%), Gaps = 1/224 (0%)

Query  13   VLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSV  72
            VL+VDDD DV  S+ RGLR SGF+V  A  G EALR  +    DA+VLD+ MP LDGV+V
Sbjct  25   VLMVDDDPDVRTSVARGLRHSGFDVRVAATGKEALRLLSSESHDALVLDVQMPELDGVAV  84

Query  73   VTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGST  132
            VTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR+ ALL RR   
Sbjct  85   VTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLHALL-RRAHH  143

Query  133  ATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVW  192
            +  +S+T+TVG L +D   R   V G  V+LTKREFDLLA LAE+   VLSR +LLELVW
Sbjct  144  SDPTSDTMTVGSLTIDTARRLVFVAGERVELTKREFDLLAALAENAGVVLSRQRLLELVW  203

Query  193  GYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            GYDF  DTNV DVF+ YLRRKLE  G PR++HTVRG+G+VLR +
Sbjct  204  GYDFDVDTNVADVFVSYLRRKLERDGLPRVIHTVRGIGYVLREE  247


>gi|169629014|ref|YP_001702663.1| putative transcriptional regulatory protein PrrA [Mycobacterium 
abscessus ATCC 19977]
 gi|169240981|emb|CAM62009.1| Putative transcriptional regulatory protein PrrA [Mycobacterium 
abscessus]
Length=236

 Score =  257 bits (656),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 144/226 (64%), Positives = 179/226 (80%), Gaps = 1/226 (0%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            +VL+VDDD DV  S+ RGLR SGF+V  AVDG +AL     + PDA+VLD+ MP LDGV+
Sbjct  10   KVLMVDDDPDVRNSVARGLRHSGFDVRVAVDGRDALTQLAADEPDALVLDVQMPELDGVA  69

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
            VVTALRA+ ND+P+CVLSAR +V+DR+AGLEAGADDYL KPF L ELVAR++ALLRRRG+
Sbjct  70   VVTALRALGNDIPICVLSARDTVNDRIAGLEAGADDYLTKPFDLGELVARLRALLRRRGA  129

Query  132  TATSSSET-ITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLEL  190
             +   +++ ITVG + VD+  R   VNG  V+L+KREFDLL VLAE+   VLSR +LLEL
Sbjct  130  GSGGLADSAITVGQITVDVSRRLVFVNGERVELSKREFDLLVVLAENTGVVLSRTRLLEL  189

Query  191  VWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            VWGYDF  +TNV DVF+ YLRRKLEAGG  R++HTVRGVG+V+R +
Sbjct  190  VWGYDFDVETNVADVFVSYLRRKLEAGGAARVIHTVRGVGYVMREE  235


>gi|240172708|ref|ZP_04751367.1| transcriptional regulatory protein PrrA [Mycobacterium kansasii 
ATCC 12478]
Length=242

 Score =  243 bits (620),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 135/228 (60%), Positives = 170/228 (75%), Gaps = 1/228 (0%)

Query  10   SPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDG  69
            +P +LVV DD DVL SLERGLRLSGF++ +A  G +AL    E RP A+V+DI+ P L G
Sbjct  14   TPSLLVVADDEDVLTSLERGLRLSGFDMTSAKTGPDALGVLAEARPQAVVVDIDQPTLRG  73

Query  70   VSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR  129
            VSVV+A+R++DN +PVCVLS RS++ DRV GL  GADD++ KP+ L+ELV RV+ LL   
Sbjct  74   VSVVSAVRSVDNRIPVCVLSGRSAISDRVPGLAEGADDFMYKPYRLSELVTRVRGLLCPP  133

Query  130  GSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLE  189
                  S+ETI+VGPL V+   RRA +NG+++ LT+REFDLLAVLA+H T +LSRA+LLE
Sbjct  134  VLVTNFSTETISVGPLMVETGRRRASINGIEIQLTRREFDLLAVLAQHATEILSRARLLE  193

Query  190  LVWG-YDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ  236
            LVWG   FAADT VVD FI  +R KL+   GPRLLHTV   GFVLR+Q
Sbjct  194  LVWGNSHFAADTRVVDAFIDSVRSKLDLVCGPRLLHTVPSAGFVLRVQ  241


>gi|118473019|ref|YP_889726.1| DNA-binding response regulator [Mycobacterium smegmatis str. 
MC2 155]
 gi|160012470|sp|A0R3I8.1|MPRA_MYCS2 RecName: Full=Response regulator mprA; AltName: Full=Mycobacterial 
persistence regulator A
 gi|118174306|gb|ABK75202.1| DNA-binding response regulator [Mycobacterium smegmatis str. 
MC2 155]
Length=230

 Score =  226 bits (576),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 118/223 (53%), Positives = 154/223 (70%), Gaps = 0/223 (0%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDDD  V  SL R L  +G+ V  A DG EAL + T NRPDA++LD+ MP LDG+ 
Sbjct  4    RILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDAITNNRPDALILDVMMPRLDGLE  63

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
            V   LR+  +D+P+ VL+AR SV +RVAGL+AGADDYL KPF L EL+AR++ALLRR  S
Sbjct  64   VCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTVS  123

Query  132  TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELV  191
              +  S+ +T   L +D   R     G  + LT+ EF LL +L  +   VL+R+++LE V
Sbjct  124  DDSGDSQKMTFSDLTLDPVTREVTRGGRQISLTRTEFSLLEMLIANPRRVLTRSRILEEV  183

Query  192  WGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            WG+DF    N ++V+IGYLRRK EA G PRL+HTVRGVG+VLR
Sbjct  184  WGFDFPTSGNALEVYIGYLRRKTEAEGEPRLIHTVRGVGYVLR  226


>gi|336115936|ref|YP_004570702.1| two-component system response regulator MprA [Microlunatus phosphovorus 
NM-1]
 gi|334683714|dbj|BAK33299.1| two-component system response regulator MprA [Microlunatus phosphovorus 
NM-1]
Length=231

 Score =  223 bits (569),  Expect = 1e-56, Method: Compositional matrix adjust.
 Identities = 115/226 (51%), Positives = 152/226 (68%), Gaps = 3/226 (1%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            ++LVVDDD  V  SL+R L+ +G+EV TA DG +A+     NRPDA+++D+ MP LDG+ 
Sbjct  2    QILVVDDDQAVRDSLQRSLQYNGYEVTTAEDGLQAMAKLAANRPDAVIMDVMMPRLDGLE  61

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
                LRA  NDVP+ VL+AR +V DRV GL+AG DDY+ KPF L EL+AR++AL+RR G+
Sbjct  62   ATRMLRAAGNDVPILVLTARDAVTDRVDGLDAGGDDYMAKPFALDELLARLRALVRRAGT  121

Query  132  TATS---SSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLL  188
            TA S   S++ +T   L ++   R        ++LT+ EF LL     H   VL R+ LL
Sbjct  122  TADSNDPSTQALTFSDLVLNTQTREVLRGSRSINLTRTEFALLEAFMHHPRRVLERSWLL  181

Query  189  ELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
              VWG+DF    N ++V+IGYLRRK EA G PRLLHTVRGVG+VLR
Sbjct  182  NEVWGFDFPTTANSLEVYIGYLRRKTEANGEPRLLHTVRGVGYVLR  227


>gi|296140967|ref|YP_003648210.1| winged helix family two component transcriptional regulator [Tsukamurella 
paurometabola DSM 20162]
 gi|296029101|gb|ADG79871.1| two component transcriptional regulator, winged helix family 
[Tsukamurella paurometabola DSM 20162]
Length=228

 Score =  223 bits (568),  Expect = 2e-56, Method: Compositional matrix adjust.
 Identities = 117/223 (53%), Positives = 152/223 (69%), Gaps = 0/223 (0%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDDD  V  SL R L  +G++V TAVDG +AL     NRPDA+VLD+NMP LDG+ 
Sbjct  2    RILVVDDDRAVRESLRRSLTFNGYQVDTAVDGQDALDHIASNRPDALVLDLNMPRLDGLE  61

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
            V   LR+  +D+P+ VL+AR  V DRV+GL+AGADDYL KPF L EL+AR++ALLRR   
Sbjct  62   VCRRLRSAGDDLPILVLTARDGVSDRVSGLDAGADDYLPKPFALEELLARMRALLRRAVP  121

Query  132  TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELV  191
               S +E +    L +D   R        + LT+ EF LL +L  +   VL+R+++LE V
Sbjct  122  DTASDNEVLRFEDLTLDPATREVSRGDRSISLTRTEFSLLEMLMGNPRRVLTRSRILEEV  181

Query  192  WGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            WGYDF    N ++V++GYLRRK EA G PRL+HTVRGVG+VLR
Sbjct  182  WGYDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLR  224


>gi|297625282|ref|YP_003687045.1| two-component response regulator [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
 gi|296921047|emb|CBL55585.1| two-component response regulator [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
Length=231

 Score =  221 bits (563),  Expect = 7e-56, Method: Compositional matrix adjust.
 Identities = 116/224 (52%), Positives = 148/224 (67%), Gaps = 1/224 (0%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATEN-RPDAIVLDINMPVLDGV  70
            ++LVVDDD  V  SL R L  SG+EV TA DG EAL   + N  PDA+V+D+ MP LDG+
Sbjct  4    QILVVDDDQAVRDSLARSLHYSGYEVETAEDGLEALAKLSTNLHPDAVVMDVMMPRLDGL  63

Query  71   SVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRG  130
                 LRA  NDVP+ VL+AR +V DRV GL+AGADDY+VKPF L EL+AR++AL RR  
Sbjct  64   ETTKMLRANGNDVPILVLTARDAVGDRVDGLDAGADDYMVKPFSLEELLARLRALTRRSR  123

Query  131  STATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLEL  190
              +  ++E ++   + +D   R     G  + LT+ EF LL    EH   VL R+ LL  
Sbjct  124  PESQQANEVLSFADMTLDPQTREVTRGGRRISLTRTEFALLQTFMEHPGKVLDRSWLLNE  183

Query  191  VWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            VWG+DF A  N ++V+IGYLRRK E  G PRL+HTVRGVG+VLR
Sbjct  184  VWGFDFPATANSLEVYIGYLRRKTEQEGEPRLIHTVRGVGYVLR  227


>gi|269926213|ref|YP_003322836.1| two component transcriptional regulator, winged helix family 
[Thermobaculum terrenum ATCC BAA-798]
 gi|269789873|gb|ACZ42014.1| two component transcriptional regulator, winged helix family 
[Thermobaculum terrenum ATCC BAA-798]
Length=228

 Score =  221 bits (562),  Expect = 9e-56, Method: Compositional matrix adjust.
 Identities = 112/224 (50%), Positives = 152/224 (68%), Gaps = 4/224 (1%)

Query  11   PRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGV  70
            P +LV+DDD ++ + L R L  +G+EV TA +G E L+ A  N PD ++LD  MP +DG+
Sbjct  4    PLILVIDDDKNITSFLRRALSYAGYEVKTAHNGQEGLQVALSNAPDLVILDWLMPDMDGI  63

Query  71   SVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRG  130
             V   LR+ DN +P+ +L+A+  V DRV GLEAGADDYLVKPF   EL+ARVKALLRR  
Sbjct  64   EVCKRLRSADN-IPILMLTAKDEVSDRVQGLEAGADDYLVKPFAHEELIARVKALLRR--  120

Query  131  STATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLEL  190
              +  S + +    L VD+  R  +     +DLT +EFDLL    +H   VL+R QLL++
Sbjct  121  -ASPDSRKVLRFADLSVDLGTREVKRGQRVIDLTAKEFDLLVTFMQHPRQVLTRDQLLQI  179

Query  191  VWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            VWG+D   +++VV V++GYLR KLEAGG  RL+HT+RGVG+VLR
Sbjct  180  VWGFDMEVESHVVAVYVGYLRDKLEAGGESRLIHTLRGVGYVLR  223


>gi|295837513|ref|ZP_06824446.1| DNA-binding response regulator [Streptomyces sp. SPB74]
 gi|295826557|gb|EFG64921.1| DNA-binding response regulator [Streptomyces sp. SPB74]
Length=244

 Score =  219 bits (558),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 116/227 (52%), Positives = 149/227 (66%), Gaps = 4/227 (1%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDD+  V  +L R L   G+ V  A DG EALR A    PD +VLDI MP +DG++
Sbjct  14   RILVVDDEPAVREALRRSLVFEGYGVEVAADGHEALRQAAATPPDLVVLDIQMPGMDGLT  73

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--  129
                LRA  + VPV +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  74   AARRLRATGSTVPVLMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  133

Query  130  --GSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQL  187
                 A    ET++ G L +++  R     G  V+LT+ EF LL +   H   VL+R Q+
Sbjct  134  AVAEQAADDEETLSFGDLRMNLATREVTRGGRAVELTRTEFTLLEMFLAHPRQVLTREQI  193

Query  188  LELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR
Sbjct  194  LKTVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLR  240


>gi|333025498|ref|ZP_08453562.1| putative two-component system response regulator [Streptomyces 
sp. Tu6071]
 gi|332745350|gb|EGJ75791.1| putative two-component system response regulator [Streptomyces 
sp. Tu6071]
Length=264

 Score =  218 bits (554),  Expect = 8e-55, Method: Compositional matrix adjust.
 Identities = 115/227 (51%), Positives = 148/227 (66%), Gaps = 4/227 (1%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDD+  V  +L R L   G+ V  A DG EAL+ A    PD +VLDI MP +DG++
Sbjct  34   RILVVDDEPAVREALRRSLVFEGYGVEVAADGHEALQKAAATPPDLVVLDIQMPGMDGLT  93

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--  129
                LRA  + VPV +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  94   AARRLRATGSTVPVLMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  153

Query  130  --GSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQL  187
                 A    ET+  G L +++  R     G  V+LT+ EF LL +   H   VL+R Q+
Sbjct  154  AVAQQAADDEETLAFGDLRMNLATREVTRGGRAVELTRTEFTLLEMFLAHPRQVLTREQI  213

Query  188  LELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR
Sbjct  214  LKTVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLR  260


>gi|108801265|ref|YP_641462.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119870416|ref|YP_940368.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|126437246|ref|YP_001072937.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 6 more sequence titles
 Length=230

 Score =  217 bits (553),  Expect = 9e-55, Method: Compositional matrix adjust.
 Identities = 116/223 (53%), Positives = 148/223 (67%), Gaps = 0/223 (0%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDDD  V  SL R L  +G+ V  A DG EAL     NRPDA+VLD+ MP LDG+ 
Sbjct  4    RILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDLIANNRPDAVVLDVMMPRLDGLE  63

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
            V   LR+  +D+P+ VL+AR SV +RVAGL+AGADDYL KPF L EL+AR++ALLRR   
Sbjct  64   VCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTSP  123

Query  132  TATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELV  191
                 S  +T   L +D   R        + LT+ EF LL +L  +   VL+R+++LE V
Sbjct  124  DEGPDSPALTFLDLTLDPVTREVTRGSRQISLTRTEFALLEMLIANPRRVLTRSRILEEV  183

Query  192  WGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            WG+DF    N ++V+IGYLRRK EA G PRL+HTVRGVG+VLR
Sbjct  184  WGFDFPTSGNALEVYIGYLRRKTEASGEPRLIHTVRGVGYVLR  226


>gi|29830590|ref|NP_825224.1| two-component system response regulator [Streptomyces avermitilis 
MA-4680]
 gi|29607702|dbj|BAC71759.1| putative two-component system response regulator [Streptomyces 
avermitilis MA-4680]
Length=243

 Score =  217 bits (553),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 111/227 (49%), Positives = 150/227 (67%), Gaps = 4/227 (1%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+L+VDD+  V  +L+R L   G++   AVDGA+AL  AT  +PD +VLDI MP +DG++
Sbjct  12   RILIVDDEPAVREALQRSLAFEGYDTEVAVDGADALEKATAYQPDLVVLDIQMPRMDGLT  71

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
                +R      P+ +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  72   AARRIRGAGTTTPILMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  131

Query  132  TATS----SSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQL  187
             AT+      + +T G L +D+  R     G  V+L + EF LL +   H   VL+R Q+
Sbjct  132  AATAVGVPEDDALTFGDLRMDLATREVTRGGRSVELIRTEFTLLEMFLAHPRQVLTREQI  191

Query  188  LELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR
Sbjct  192  LKAVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLR  238


>gi|158317067|ref|YP_001509575.1| two component transcriptional regulator [Frankia sp. EAN1pec]
 gi|158112472|gb|ABW14669.1| two component transcriptional regulator, winged helix family 
[Frankia sp. EAN1pec]
Length=246

 Score =  217 bits (553),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 118/238 (50%), Positives = 153/238 (65%), Gaps = 15/238 (6%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            RVLVVDDD+ V  SLER LR  G+EV TA DG  AL     ++PD +VLD+ MP +DG+ 
Sbjct  2    RVLVVDDDAAVRESLERSLRFEGYEVRTAPDGVAALEVVARDQPDIVVLDVMMPRMDGLE  61

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--  129
                LRA  +DVPV +L+AR  + DRV+GL+ GADDYLVKPF L EL AR++AL+RR   
Sbjct  62   TCRRLRARGDDVPVLMLTARDGLADRVSGLDVGADDYLVKPFALEELFARLRALIRRSTL  121

Query  130  ------GSTATSSSE-------TITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAE  176
                  G      +E        ++   + +D   R+    G ++ LTK EF+LL +   
Sbjct  122  VTRAGVGHGPAHGAEPGHGVPAALSYAGVALDPASRQVLREGRELTLTKTEFELLELFLT  181

Query  177  HKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            H   VLSR+ ++E VWGYDF   +N ++VF+ YLRRKLEAGG PRLLHTVRGVG+VLR
Sbjct  182  HPRQVLSRSMIMEKVWGYDFGPSSNSLEVFVSYLRRKLEAGGEPRLLHTVRGVGYVLR  239


>gi|289770266|ref|ZP_06529644.1| two-component system response regulator [Streptomyces lividans 
TK24]
 gi|289700465|gb|EFD67894.1| two-component system response regulator [Streptomyces lividans 
TK24]
Length=248

 Score =  217 bits (552),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 112/229 (49%), Positives = 150/229 (66%), Gaps = 5/229 (2%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+L+VDD+  V  +L+R L   G++   AVDGA+AL  AT  RPD +VLDI MP +DG++
Sbjct  16   RILIVDDEPAVREALQRSLAFEGYDTEVAVDGADALEKATAYRPDLVVLDIQMPRMDGLT  75

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
                +R   +  P+ +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  76   AARRIRGAGDLTPIVMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  135

Query  132  TA-----TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQ  186
             A         +T+T   L +D+  R     G  V+LT+ EF LL +   H   VL+R Q
Sbjct  136  AAAVEATAEDDDTLTFADLTMDLATREVSRAGRPVELTRTEFTLLEMFMAHPRQVLTREQ  195

Query  187  LLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRM  235
            +L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR 
Sbjct  196  ILKAVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLRQ  244


>gi|302520777|ref|ZP_07273119.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. SPB78]
 gi|302429672|gb|EFL01488.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. SPB78]
Length=244

 Score =  217 bits (552),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 115/227 (51%), Positives = 148/227 (66%), Gaps = 4/227 (1%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+LVVDD+  V  +L R L   G+ V  A DG EAL+ A    PD +VLDI MP +DG++
Sbjct  14   RILVVDDEPAVREALRRSLVFEGYGVEVAADGHEALQKAAATPPDLVVLDIQMPGMDGLT  73

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRR--  129
                LRA  + VPV +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  74   AARRLRATGSTVPVLMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  133

Query  130  --GSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQL  187
                 A    ET+  G L +++  R     G  V+LT+ EF LL +   H   VL+R Q+
Sbjct  134  AVAQQAADDEETLAFGDLRMNLATREVTRGGRAVELTRTEFTLLEMFLAHPRQVLTREQI  193

Query  188  LELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR  234
            L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR
Sbjct  194  LKTVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLR  240


>gi|21222554|ref|NP_628333.1| two-component systen response regulator [Streptomyces coelicolor 
A3(2)]
 gi|7636029|emb|CAB88489.1| putative two-component systen response regulator [Streptomyces 
coelicolor A3(2)]
Length=248

 Score =  217 bits (552),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 112/229 (49%), Positives = 150/229 (66%), Gaps = 5/229 (2%)

Query  12   RVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVS  71
            R+L+VDD+  V  +L+R L   G++   AVDGA+AL  AT  RPD +VLDI MP +DG++
Sbjct  16   RILIVDDEPAVREALQRSLAFEGYDTEVAVDGADALEKATAYRPDLVVLDIQMPRMDGLT  75

Query  72   VVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGS  131
                +R   +  P+ +L+AR +V DRV GL+AGADDYLVKPF L EL AR++ALLRR   
Sbjct  76   AARRIRGAGDLTPILMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRRSSY  135

Query  132  TA-----TSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQ  186
             A         +T+T   L +D+  R     G  V+LT+ EF LL +   H   VL+R Q
Sbjct  136  AAAVEATAEDDDTLTFADLTMDLATREVSRAGRPVELTRTEFTLLEMFMAHPRQVLTREQ  195

Query  187  LLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRM  235
            +L+ VWG+DF   +N +DV++ YLRRK EAGG PRL+HTVRGVG+VLR 
Sbjct  196  ILKAVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLRQ  244



Lambda     K      H
   0.320    0.137    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 319551017258




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40