BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0906 Length=372 Score E Sequences producing significant alignments: (Bits) Value gi|15608046|ref|NP_215421.1| hypothetical protein Rv0906 [Mycoba... 744 0.0 gi|254363836|ref|ZP_04979882.1| conserved hypothetical protein [... 740 0.0 gi|183984591|ref|YP_001852882.1| hypothetical protein MMAR_4624 ... 645 0.0 gi|240172195|ref|ZP_04750854.1| hypothetical protein MkanA1_2296... 642 0.0 gi|118616118|ref|YP_904450.1| hypothetical protein MUL_0235 [Myc... 634 6e-180 gi|296169664|ref|ZP_06851282.1| beta-lactamase superfamily Zn-de... 603 2e-170 gi|342860512|ref|ZP_08717163.1| metallo-beta-lactamase [Mycobact... 598 4e-169 gi|41406939|ref|NP_959775.1| hypothetical protein MAP0841 [Mycob... 593 1e-167 gi|118463201|ref|YP_880285.1| metallo-beta-lactamase [Mycobacter... 593 2e-167 gi|254822959|ref|ZP_05227960.1| hypothetical protein MintA_23729... 591 7e-167 gi|336461279|gb|EGO40153.1| putative Zn-dependent hydrolase of b... 589 3e-166 gi|126437376|ref|YP_001073067.1| hypothetical protein Mjls_4811 ... 505 4e-141 gi|108801393|ref|YP_641590.1| hypothetical protein Mmcs_4430 [My... 505 5e-141 gi|120405940|ref|YP_955769.1| hypothetical protein Mvan_4991 [My... 489 3e-136 gi|118468401|ref|YP_889872.1| metallo-beta-lactamase [Mycobacter... 480 2e-133 gi|333989469|ref|YP_004522083.1| hypothetical protein JDM601_082... 479 2e-133 gi|145222346|ref|YP_001133024.1| beta-lactamase domain-containin... 477 1e-132 gi|169628057|ref|YP_001701706.1| hypothetical protein MAB_0960 [... 441 8e-122 gi|111022001|ref|YP_704973.1| hypothetical protein RHA1_ro05034 ... 408 6e-112 gi|226364508|ref|YP_002782290.1| hypothetical protein ROP_50980 ... 407 2e-111 gi|289442317|ref|ZP_06432061.1| LOW QUALITY PROTEIN: conserved h... 389 5e-106 gi|284988838|ref|YP_003407392.1| beta-lactamase domain-containin... 388 8e-106 gi|226308026|ref|YP_002767986.1| hypothetical protein RER_45390 ... 387 1e-105 gi|54022642|ref|YP_116884.1| hypothetical protein nfa6750 [Nocar... 384 1e-104 gi|331697770|ref|YP_004334009.1| beta-lactamase domain-containin... 379 5e-103 gi|325676219|ref|ZP_08155899.1| multidrug resistance protein Rom... 379 6e-103 gi|289752962|ref|ZP_06512340.1| conserved hypothetical protein [... 378 8e-103 gi|312138495|ref|YP_004005831.1| metallo-beta-lactamase superfam... 376 4e-102 gi|229488966|ref|ZP_04382832.1| metallo-beta-lactamase family pr... 375 7e-102 gi|333918536|ref|YP_004492117.1| hypothetical protein AS9A_0865 ... 374 2e-101 gi|258650385|ref|YP_003199541.1| beta-lactamase fold-like Zn-dep... 369 6e-100 gi|238063763|ref|ZP_04608472.1| zinc-dependent hydrolase [Microm... 363 2e-98 gi|311899072|dbj|BAJ31480.1| hypothetical protein KSE_57070 [Kit... 358 9e-97 gi|257055482|ref|YP_003133314.1| putative Zn-dependent hydrolase... 357 2e-96 gi|289568873|ref|ZP_06449100.1| conserved hypothetical protein [... 356 3e-96 gi|289752961|ref|ZP_06512339.1| conserved hypothetical protein [... 353 2e-95 gi|296269651|ref|YP_003652283.1| beta-lactamase domain-containin... 352 4e-95 gi|271965366|ref|YP_003339562.1| hypothetical protein Sros_3902 ... 350 2e-94 gi|315503022|ref|YP_004081909.1| zn-dependent hydrolase [Micromo... 350 2e-94 gi|302866614|ref|YP_003835251.1| Zn-dependent hydrolase [Micromo... 349 4e-94 gi|296141042|ref|YP_003648285.1| hypothetical protein Tpau_3362 ... 344 1e-92 gi|330466773|ref|YP_004404516.1| zn-dependent hydrolase of the b... 343 4e-92 gi|256379964|ref|YP_003103624.1| hypothetical protein Amir_5970 ... 342 6e-92 gi|145594252|ref|YP_001158549.1| Zn-dependent hydrolase of the b... 337 2e-90 gi|345010512|ref|YP_004812866.1| hypothetical protein Strvi_2887... 336 3e-90 gi|159037329|ref|YP_001536582.1| Zn-dependent hydrolase of the b... 332 5e-89 gi|300784434|ref|YP_003764725.1| Zn-dependent hydrolase of the b... 332 6e-89 gi|302525672|ref|ZP_07278014.1| metallo-beta-lactamase [Streptom... 325 1e-86 gi|329937118|ref|ZP_08286747.1| metallo-beta-lactamase [Streptom... 324 1e-86 gi|302541316|ref|ZP_07293658.1| metallo-beta-lactamase [Streptom... 324 2e-86 >gi|15608046|ref|NP_215421.1| hypothetical protein Rv0906 [Mycobacterium tuberculosis H37Rv] gi|15840325|ref|NP_335362.1| hypothetical protein MT0929 [Mycobacterium tuberculosis CDC1551] gi|31792094|ref|NP_854587.1| hypothetical protein Mb0930 [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=372 Score = 744 bits (1921), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/372 (100%), Positives = 372/372 (100%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA Sbjct 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID Sbjct 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV Sbjct 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT Sbjct 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE Sbjct 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP Sbjct 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 Query 361 TGPMRLHPWWRL 372 TGPMRLHPWWRL Sbjct 361 TGPMRLHPWWRL 372 >gi|254363836|ref|ZP_04979882.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|289555312|ref|ZP_06444522.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 605] gi|134149350|gb|EBA41395.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|289439944|gb|EFD22437.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 605] Length=371 Score = 740 bits (1911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/371 (99%), Positives = 371/371 (100%), Gaps = 0/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +RRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS Sbjct 1 MRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG Sbjct 61 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG Sbjct 121 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT Sbjct 181 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA Sbjct 241 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT Sbjct 301 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 360 Query 362 GPMRLHPWWRL 372 GPMRLHPWWRL Sbjct 361 GPMRLHPWWRL 371 >gi|183984591|ref|YP_001852882.1| hypothetical protein MMAR_4624 [Mycobacterium marinum M] gi|183177917|gb|ACC43027.1| conserved protein [Mycobacterium marinum M] Length=372 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/372 (83%), Positives = 340/372 (92%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 MV RALRLAAGTASLAAG WL+RALHG PAALGAD A+I A S+ SPNYRDG FVNLDPA Sbjct 1 MVGRALRLAAGTASLAAGGWLMRALHGAPAALGADPAAIEAASDGSPNYRDGVFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 S+FTL+REE+RL+ WEL+A SRPA PIPLA+P +Y+GDASRLAVSWFGHSTA++EID Sbjct 61 SVFTLNREEMRLLAWELLANRGGSRPAKPIPLAAPQVYQGDASRLAVSWFGHSTAMVEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSD+VGPQRLHPPPVQL LPAVDAVVISHDHYDHLDIDTV+ALV Sbjct 121 GYRVLTDPVWSDRCSPSDLVGPQRLHPPPVQLDGLPAVDAVVISHDHYDHLDIDTVIALV 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF VPLGVGAHLRSWGVP+DRI+ELDW+QSAQV EL+V+C+PARHFSGRF+SRN Sbjct 181 RSQRAPFFVPLGVGAHLRSWGVPEDRIIELDWHQSAQVGELSVICMPARHFSGRFMSRNN 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASWAFVGP HRAYFGGDTGYTKSF +IGADHGPFDLTL+PIGAYNT WPDIHMNPEE Sbjct 241 TLWASWAFVGPTHRAYFGGDTGYTKSFAEIGADHGPFDLTLMPIGAYNTGWPDIHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAHLDV+D+GSG+LVP+HWGTFRLAPHPW EPVERLL AAE + V VAVPLPGQR+DP Sbjct 301 AVRAHLDVSDTGSGLLVPIHWGTFRLAPHPWAEPVERLLKAAESDQVQVAVPLPGQRIDP 360 Query 361 TGPMRLHPWWRL 372 GP+R +PWWRL Sbjct 361 AGPLRFNPWWRL 372 >gi|240172195|ref|ZP_04750854.1| hypothetical protein MkanA1_22969 [Mycobacterium kansasii ATCC 12478] Length=373 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/372 (83%), Positives = 339/372 (92%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 +VRRALRLAAGTASLAAG WL+RALHG PAALGA+ A+IRA+SE SP+YRDG+FVNLDP Sbjct 2 VVRRALRLAAGTASLAAGGWLVRALHGAPAALGANPATIRAISEGSPHYRDGSFVNLDPG 61 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 S++ + REELRLI+WE V SRPA PIPLA+P IY+GDASRLAVSWFGHSTAL+EID Sbjct 62 SIYVMGREELRLILWEFVGNRGGSRPAKPIPLAAPEIYKGDASRLAVSWFGHSTALVEID 121 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSD+VGPQRLHPPPVQL LPAVDAVVISHDHYDHLDIDTV+AL Sbjct 122 GYRVLTDPVWSDRCSPSDLVGPQRLHPPPVQLEGLPAVDAVVISHDHYDHLDIDTVIALT 181 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF VPLGVGAHLR+WG+P+ RIVELDW QS QVD+L +VC+PARHFSGRFLSR+ Sbjct 182 RTQRAPFFVPLGVGAHLRAWGIPEQRIVELDWQQSGQVDQLRIVCMPARHFSGRFLSRDN 241 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASWAF+GP HRAYFGGD+GYTKSF QIGADHGPFDLTL+PIGAYNTAWPDIHMNPEE Sbjct 242 TLWASWAFIGPRHRAYFGGDSGYTKSFAQIGADHGPFDLTLMPIGAYNTAWPDIHMNPEE 301 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 A+RAHL+VTDSG+G+LVPVHWGTFRLAPHPW EPVERL+AAAEPE V VAVPLPGQRVDP Sbjct 302 AIRAHLEVTDSGAGLLVPVHWGTFRLAPHPWSEPVERLIAAAEPERVKVAVPLPGQRVDP 361 Query 361 TGPMRLHPWWRL 372 GP+R +PWWRL Sbjct 362 AGPLRSNPWWRL 373 >gi|118616118|ref|YP_904450.1| hypothetical protein MUL_0235 [Mycobacterium ulcerans Agy99] gi|118568228|gb|ABL02979.1| conserved protein [Mycobacterium ulcerans Agy99] Length=372 Score = 634 bits (1636), Expect = 6e-180, Method: Compositional matrix adjust. Identities = 304/372 (82%), Positives = 336/372 (91%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 MV RALRLAAGTASLAAG WL+RAL G PAALGAD A+I A S+ SP YRDG FVNLDPA Sbjct 1 MVGRALRLAAGTASLAAGGWLMRALRGAPAALGADPAAIEAASDGSPYYRDGVFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 S+FTL+REE+RL+ WEL+A SRPA PIPLA+P +Y+GDASRLAVSWFGHSTA++EID Sbjct 61 SVFTLNREEMRLLAWELLANRGGSRPAKPIPLAAPQVYQGDASRLAVSWFGHSTAMVEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSD+VGPQRLHPPPVQL LPAVDAVVISHDHYDHLDIDTV+ALV Sbjct 121 GYRVLTDPVWSDRCSPSDLVGPQRLHPPPVQLDGLPAVDAVVISHDHYDHLDIDTVIALV 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF VPLGVGAHLRSWGVP+DRI+E DW+QSAQV EL+V+C+PARHFSGRF+SRN Sbjct 181 RSQRAPFFVPLGVGAHLRSWGVPEDRIIEFDWHQSAQVGELSVICMPARHFSGRFMSRNN 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASWAFVGP HRAYFGGDTGYTKSF +IGADHGPFDLTL+PIGAY+T WPDIHMNPEE Sbjct 241 TLWASWAFVGPTHRAYFGGDTGYTKSFAEIGADHGPFDLTLMPIGAYSTGWPDIHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAHLDV+D+GSG+LVP+HWGTFRLAPHPW EPVERLL AAE + V VAVPLPGQ VDP Sbjct 301 AVRAHLDVSDTGSGLLVPIHWGTFRLAPHPWAEPVERLLKAAESDQVQVAVPLPGQGVDP 360 Query 361 TGPMRLHPWWRL 372 GP+R +PWWRL Sbjct 361 AGPLRFNPWWRL 372 >gi|296169664|ref|ZP_06851282.1| beta-lactamase superfamily Zn-dependent hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895661|gb|EFG75357.1| beta-lactamase superfamily Zn-dependent hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=370 Score = 603 bits (1554), Expect = 2e-170, Method: Compositional matrix adjust. Identities = 302/372 (82%), Positives = 330/372 (89%), Gaps = 2/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 M+R ALRLAAGTASLAAG+WL+RALHG PAALGA ++IRA ++ SPNYRDG FVNLDPA Sbjct 1 MLRGALRLAAGTASLAAGSWLVRALHGAPAALGAHPSAIRAAAQGSPNYRDGVFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 S FT+DREE+RL+ WEL+ SRP APIPLA+P I+ GD +RLAVSWFGHSTALLEID Sbjct 61 SAFTMDREEMRLVAWELIGNRGVSRPPAPIPLAAPAIFDGDPARLAVSWFGHSTALLEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSD+VGPQRLHPPPVQL LPAVDAVVISHDHYDHLDIDTV+AL Sbjct 121 GYRVLTDPVWSDRCSPSDIVGPQRLHPPPVQLEGLPAVDAVVISHDHYDHLDIDTVMALA 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF VPLGVGAHLR+WG+P+ RIVELDW QSAQVDELTV C+PARHFSGRFL RNT Sbjct 181 RTQRAPFFVPLGVGAHLRAWGIPEHRIVELDWEQSAQVDELTVTCMPARHFSGRFLDRNT 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASWAF GPN RAYFGGDTGYTKSF +IGADHGPFDLTLLPIGAYNTAWPD+HMNPEE Sbjct 241 TLWASWAFTGPNRRAYFGGDTGYTKSFARIGADHGPFDLTLLPIGAYNTAWPDVHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAHLD+TD G+LVP+HWGTFRLAPHPW EPVERLLAAAEPE V VAVP PGQRVDP Sbjct 301 AVRAHLDLTD--DGLLVPIHWGTFRLAPHPWAEPVERLLAAAEPEQVKVAVPTPGQRVDP 358 Query 361 TGPMRLHPWWRL 372 P++ +PWWR Sbjct 359 AAPVKANPWWRF 370 >gi|342860512|ref|ZP_08717163.1| metallo-beta-lactamase [Mycobacterium colombiense CECT 3035] gi|342132167|gb|EGT85408.1| metallo-beta-lactamase [Mycobacterium colombiense CECT 3035] Length=369 Score = 598 bits (1542), Expect = 4e-169, Method: Compositional matrix adjust. Identities = 295/371 (80%), Positives = 318/371 (86%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +R LRL AGTASLAAG WL+RALHG P ALGA ASI AV+ SP+YRDG FVNL+PAS Sbjct 1 MRGTLRLVAGTASLAAGGWLVRALHGAPDALGAHPASIAAVTAGSPHYRDGVFVNLEPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 +DRE+LRLI WEL+ SRP PIP+ASP + D SRLAVSWFGHSTALLEIDG Sbjct 61 DIAMDREQLRLIAWELIGNRGGSRPKGPIPVASPGMLDADPSRLAVSWFGHSTALLEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWSDRCSPSDVVGPQRLHPPP+QL ALPAVDAVVISHDHYDHLDIDTV AL Sbjct 121 YRVLTDPVWSDRCSPSDVVGPQRLHPPPIQLEALPAVDAVVISHDHYDHLDIDTVRALAR 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QRAPF VPLG+GAHLR WG+P+ R+VELDW+QSA+VDEL VVCVPARHFSGRFL RNTT Sbjct 181 TQRAPFFVPLGIGAHLRRWGIPEQRVVELDWHQSAKVDELEVVCVPARHFSGRFLDRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASWAFVGP HRAYFGGDTGYTKSF QIGADHGPFDLTLLPIGAYNTAWPD+HMNPEEA Sbjct 241 LWASWAFVGPKHRAYFGGDTGYTKSFAQIGADHGPFDLTLLPIGAYNTAWPDVHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAHLDVTD G+L+P+HWGTFRLAPHPW EPVERLLAAA PE V VAVPLPGQR+DP Sbjct 301 VRAHLDVTD--GGLLIPIHWGTFRLAPHPWAEPVERLLAAAAPERVDVAVPLPGQRIDPA 358 Query 362 GPMRLHPWWRL 372 + PWWRL Sbjct 359 VLEKSEPWWRL 369 >gi|41406939|ref|NP_959775.1| hypothetical protein MAP0841 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395289|gb|AAS03158.1| hypothetical protein MAP_0841 [Mycobacterium avium subsp. paratuberculosis K-10] Length=369 Score = 593 bits (1529), Expect = 1e-167, Method: Compositional matrix adjust. Identities = 290/371 (79%), Positives = 315/371 (85%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +R LRL AGTASLAAG WL+RALHG P ALGAD ASI V+ SP++RDGAFVNL+PAS Sbjct 1 MRGTLRLVAGTASLAAGGWLVRALHGAPDALGADPASIATVTSGSPHFRDGAFVNLEPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 +DRE+LRLI WEL+A SRP A IPLASP + D SRLAVSWFGHSTALLEIDG Sbjct 61 EIKMDREQLRLIAWELIANRGGSRPPAAIPLASPGVVDADPSRLAVSWFGHSTALLEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWS+RCSPSD+VGPQRLHPPP+QL LPAVDAVVISHDHYDHLDIDTV AL Sbjct 121 YRVLTDPVWSERCSPSDIVGPQRLHPPPIQLEGLPAVDAVVISHDHYDHLDIDTVRALAR 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QRAPF VPLGVGAHLR WG+P+ RIVELDW+QS +VDELTV CVPARHFSGRFL RNTT Sbjct 181 TQRAPFFVPLGVGAHLRRWGIPEQRIVELDWHQSGKVDELTVTCVPARHFSGRFLDRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASWA GP HRAYFGGDTGYTK+F Q GA+HGPFDLTLLPIGAYNTAWPD+HMNPEEA Sbjct 241 LWASWALAGPTHRAYFGGDTGYTKTFAQTGAEHGPFDLTLLPIGAYNTAWPDVHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAH DVTD G+LVP+HWGTFRLAPHPW EPVERLLAAAEP V VAVP+PGQR+DP Sbjct 301 VRAHRDVTD--DGLLVPIHWGTFRLAPHPWAEPVERLLAAAEPAKVKVAVPVPGQRIDPA 358 Query 362 GPMRLHPWWRL 372 P + PWWRL Sbjct 359 APQKPDPWWRL 369 >gi|118463201|ref|YP_880285.1| metallo-beta-lactamase [Mycobacterium avium 104] gi|254773916|ref|ZP_05215432.1| metallo-beta-lactamase family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118164488|gb|ABK65385.1| metallo-beta-lactamase family protein [Mycobacterium avium 104] Length=369 Score = 593 bits (1528), Expect = 2e-167, Method: Compositional matrix adjust. Identities = 290/371 (79%), Positives = 316/371 (86%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +R LRL AGTASLAAG WL+RALHG P ALGAD ASI AV+ SP++RDGAFVNL+PAS Sbjct 1 MRGTLRLVAGTASLAAGGWLVRALHGAPDALGADPASIAAVTSGSPHFRDGAFVNLEPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 +DRE+LRLI WEL+A SRP A IPLASP + D SRLAVSWFGHSTALLEIDG Sbjct 61 EIKMDREQLRLIAWELIANRGGSRPPAAIPLASPGVVDADPSRLAVSWFGHSTALLEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWS+RCSPSD+VGPQRLHPPP+QL LPAVDAVVISHDHYDHLDIDTV AL Sbjct 121 YRVLTDPVWSERCSPSDIVGPQRLHPPPIQLEGLPAVDAVVISHDHYDHLDIDTVRALAR 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QRAPF VPLGVGAHLR WG+P+ RIVELDW+QS +VDELTV CVPARHFSGRFL RNTT Sbjct 181 TQRAPFFVPLGVGAHLRRWGIPEQRIVELDWHQSGKVDELTVTCVPARHFSGRFLDRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASWA GP HRAYFGGDTGYTK+F Q GA+HGPFDLTLLPIGAYNTAWPD+HMNPEEA Sbjct 241 LWASWALAGPTHRAYFGGDTGYTKTFAQTGAEHGPFDLTLLPIGAYNTAWPDVHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAH DVT+ G+LVP+HWGTFRLAPHPW EPVERLLAAAEP V VAVP+PGQR+DP Sbjct 301 VRAHRDVTN--DGLLVPIHWGTFRLAPHPWAEPVERLLAAAEPAKVKVAVPVPGQRIDPA 358 Query 362 GPMRLHPWWRL 372 P + PWWRL Sbjct 359 APQKPDPWWRL 369 >gi|254822959|ref|ZP_05227960.1| hypothetical protein MintA_23729 [Mycobacterium intracellulare ATCC 13950] Length=369 Score = 591 bits (1523), Expect = 7e-167, Method: Compositional matrix adjust. Identities = 290/371 (79%), Positives = 315/371 (85%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +R LRL AGTASLA G WLLRALHG P ALGA ASI A + SPN RDG FVNL+PAS Sbjct 1 MRGTLRLIAGTASLAGGGWLLRALHGAPDALGAHPASIAAATAGSPNCRDGVFVNLEPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 +DRE+LRLI WELV SRP PIPL +P ++R D S LAVSWFGHSTAL+EIDG Sbjct 61 ETKMDREQLRLIAWELVGNRGGSRPRGPIPLTAPGVFRADPSGLAVSWFGHSTALVEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWSDRCSPSDVVGPQRLHPPP+QL LPAVDAVVISHDHYDHLDIDT+ AL Sbjct 121 YRVLTDPVWSDRCSPSDVVGPQRLHPPPIQLEGLPAVDAVVISHDHYDHLDIDTIRALAR 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QR+PF VPLGVGAHLR WG+P+ RIVELDW+QSA VDELTVVCVPARHFSGRFL RNTT Sbjct 181 TQRSPFFVPLGVGAHLRRWGIPEHRIVELDWHQSATVDELTVVCVPARHFSGRFLDRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASW F GP HRAYFGGDTGYTKSF QIGADHGPFDLTLLPIGAYNTAWPD+HMNPEEA Sbjct 241 LWASWVFRGPTHRAYFGGDTGYTKSFAQIGADHGPFDLTLLPIGAYNTAWPDVHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 +RAHLDVTD G+LVP+HWGTFRLAPHPW EPVERLLAAAEPE V VAVP+PGQR+D Sbjct 301 LRAHLDVTD--GGLLVPIHWGTFRLAPHPWAEPVERLLAAAEPEQVNVAVPVPGQRIDLA 358 Query 362 GPMRLHPWWRL 372 P++ +PWW+L Sbjct 359 APVKSNPWWQL 369 >gi|336461279|gb|EGO40153.1| putative Zn-dependent hydrolase of beta-lactamase [Mycobacterium avium subsp. paratuberculosis S397] Length=369 Score = 589 bits (1518), Expect = 3e-166, Method: Compositional matrix adjust. Identities = 289/371 (78%), Positives = 314/371 (85%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 +R LRL AGTASLAAG WL+RALHG P ALGAD ASI V+ SP++RDGAFVNL+PAS Sbjct 1 MRGTLRLVAGTASLAAGGWLVRALHGAPDALGADPASIATVTSGSPHFRDGAFVNLEPAS 60 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 +DRE+LRLI WEL+A SRP A IPLASP + D SRLAVSWFGHSTALLEIDG Sbjct 61 EIKMDREQLRLIAWELIANRGGSRPPAAIPLASPGVVDADPSRLAVSWFGHSTALLEIDG 120 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVLTDPVWS+RCSPSD+VGPQRLHPPP+QL LPAVDAVVISHDHYDHLDIDTV AL Sbjct 121 YRVLTDPVWSERCSPSDIVGPQRLHPPPIQLEGLPAVDAVVISHDHYDHLDIDTVRALAR 180 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QRAPF VPLGVGAHLR G+P+ RIVELDW+QS +VDELTV CVPARHFSGRFL RNTT Sbjct 181 TQRAPFFVPLGVGAHLRRRGIPEQRIVELDWHQSGKVDELTVTCVPARHFSGRFLDRNTT 240 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LWASWA GP HRAYFGGDTGYTK+F Q GA+HGPFDLTLLPIGAYNTAWPD+HMNPEEA Sbjct 241 LWASWALAGPTHRAYFGGDTGYTKTFAQTGAEHGPFDLTLLPIGAYNTAWPDVHMNPEEA 300 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAH DVTD G+LVP+HWGTFRLAPHPW EPVERLLAAAEP V VAVP+PGQR+DP Sbjct 301 VRAHRDVTD--DGLLVPIHWGTFRLAPHPWAEPVERLLAAAEPAKVKVAVPVPGQRIDPA 358 Query 362 GPMRLHPWWRL 372 P + PWWRL Sbjct 359 APQKPDPWWRL 369 >gi|126437376|ref|YP_001073067.1| hypothetical protein Mjls_4811 [Mycobacterium sp. JLS] gi|126237176|gb|ABO00577.1| conserved hypothetical protein [Mycobacterium sp. JLS] Length=372 Score = 505 bits (1301), Expect = 4e-141, Method: Compositional matrix adjust. Identities = 241/372 (65%), Positives = 288/372 (78%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 M+ ALR GTAS+ AG W+LRAL GTPA+LGA A I V+ +S NYR+G FVNL+PA Sbjct 1 MLGAALRYGFGTASVLAGGWVLRALQGTPASLGATPAEIHPVARRSGNYREGVFVNLEPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 ++D E R++V EL RP APIP+ +P +A+ LA W GHST ++E+D Sbjct 61 DTISMDAEARRMLVRELFLGREKGRPGAPIPVVAPAPVTAEAAGLAAYWHGHSTTVVEVD 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDP+WSDRCSPS VGPQR+H PP L LPAVDAV+ISHDHYDHLDIDT++ L Sbjct 121 GYRVLTDPIWSDRCSPSRTVGPQRMHEPPTPLEQLPAVDAVLISHDHYDHLDIDTILGLA 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF+VPLGVGAHLR WG+ RIVELDWN+S ++ ELT+VC PARHFSGR SRNT Sbjct 181 RTQRAPFVVPLGVGAHLRKWGISDARIVELDWNESHRIGELTLVCTPARHFSGRLFSRNT 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASW GP HR +FGGDTGYT SF++IG+ HGPFDLTLLP+GAY+ AWPDIHMNPEE Sbjct 241 TLWASWVIAGPKHRVFFGGDTGYTASFSEIGSQHGPFDLTLLPVGAYHPAWPDIHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAH D+TD+G G+L+P+HWGTFRLAPHPW EPV+RLLAAA+P V+V VP PGQRV+ Sbjct 301 AVRAHQDMTDAGGGVLLPIHWGTFRLAPHPWAEPVQRLLAAADPAGVSVVVPKPGQRVER 360 Query 361 TGPMRLHPWWRL 372 + PWW+L Sbjct 361 GASPAIEPWWQL 372 >gi|108801393|ref|YP_641590.1| hypothetical protein Mmcs_4430 [Mycobacterium sp. MCS] gi|119870546|ref|YP_940498.1| hypothetical protein Mkms_4517 [Mycobacterium sp. KMS] gi|108771812|gb|ABG10534.1| conserved hypothetical protein [Mycobacterium sp. MCS] gi|119696635|gb|ABL93708.1| conserved hypothetical protein [Mycobacterium sp. KMS] Length=372 Score = 505 bits (1300), Expect = 5e-141, Method: Compositional matrix adjust. Identities = 241/372 (65%), Positives = 288/372 (78%), Gaps = 0/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 M+ ALR GTAS+ AG W+LRAL GTPA+LGA A I V+ +S NYR+G FVNL+PA Sbjct 1 MLGAALRYGFGTASVLAGGWVLRALQGTPASLGATPAEIHPVARRSGNYREGVFVNLEPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 ++D E R++V EL RP APIP+ +P +A+ LA W GHST ++E+D Sbjct 61 DTISMDAEARRMLVRELFLGREKGRPGAPIPVVAPAPVTAEAAGLAAYWHGHSTTVVEVD 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDP+WSDRCSPS VGPQR+H PP L LPAVDAV+ISHDHYDHLDIDT++ L Sbjct 121 GYRVLTDPIWSDRCSPSRTVGPQRMHEPPTPLEQLPAVDAVLISHDHYDHLDIDTILGLA 180 Query 181 GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT 240 QRAPF+VPLGVGAHLR WG+ RIVELDWN+S ++ ELT+VC PARHFSGR SRNT Sbjct 181 RTQRAPFVVPLGVGAHLRKWGISDARIVELDWNESHRIGELTLVCTPARHFSGRLFSRNT 240 Query 241 TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 TLWASW GP HR +FGGDTGYT SF++IG+ HGPFDLTLLP+GAY+ AWPDIHMNPEE Sbjct 241 TLWASWVIAGPEHRVFFGGDTGYTASFSEIGSQHGPFDLTLLPVGAYHPAWPDIHMNPEE 300 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP 360 AVRAH D+TD+G G+L+P+HWGTFRLAPHPW EPV+RLLAAA+P V+V VP PGQRV+ Sbjct 301 AVRAHQDMTDAGGGVLLPIHWGTFRLAPHPWAEPVQRLLAAADPAGVSVVVPKPGQRVER 360 Query 361 TGPMRLHPWWRL 372 + PWW+L Sbjct 361 GASPAIEPWWQL 372 >gi|120405940|ref|YP_955769.1| hypothetical protein Mvan_4991 [Mycobacterium vanbaalenii PYR-1] gi|119958758|gb|ABM15763.1| conserved hypothetical protein [Mycobacterium vanbaalenii PYR-1] Length=371 Score = 489 bits (1259), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 235/371 (64%), Positives = 286/371 (78%), Gaps = 2/371 (0%) Query 2 VRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPAS 61 VR ALR GTASL AG W+LRAL GTPAALGA I V+ +SP+Y+DG FVNL+P S Sbjct 3 VRTALRFGFGTASLFAGGWVLRALQGTPAALGATPPEIAPVARRSPHYQDGKFVNLEPPS 62 Query 62 MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDG 121 T+DR+ R+++ +L S P PIPLA P + + A SW+GHS+ L+E+DG Sbjct 63 GITMDRDLQRMLLRDLANFASQGTPPGPIPLADPPVVDPTPAPAAASWYGHSSTLIEVDG 122 Query 122 YRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVG 181 YRVL DPVWS+RCSPS VGPQR+H PV + ALPAVDAV+ISHDHYDHLDIDT+VAL Sbjct 123 YRVLADPVWSNRCSPSRAVGPQRMHDVPVLIEALPAVDAVIISHDHYDHLDIDTIVALAH 182 Query 182 MQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTT 241 QRAPF+VPLG+GAHLR WG+P+ RIVELDWN++ ++ +LT++C PARHFSGR +R++T Sbjct 183 TQRAPFVVPLGIGAHLRKWGIPESRIVELDWNEAHRIGDLTLICTPARHFSGRLFARDST 242 Query 242 LWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEA 301 LW+SW GP H+A+FGGDTGYTKSF +IGA+HGPFDLTLLPIGAY+ A+ DIHMNPEEA Sbjct 243 LWSSWVVTGPTHKAFFGGDTGYTKSFAEIGAEHGPFDLTLLPIGAYHPAFADIHMNPEEA 302 Query 302 VRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPT 361 VRAHLD+ D + ++VP+HW TFRLAPHPW EP ERLL AA+ E V VAVP+PGQRV P Sbjct 303 VRAHLDLADVDNSLMVPIHWATFRLAPHPWAEPAERLLTAADAERVRVAVPMPGQRVVPE 362 Query 362 GPMRLHPWWRL 372 PWWR Sbjct 363 S--TFDPWWRF 371 >gi|118468401|ref|YP_889872.1| metallo-beta-lactamase [Mycobacterium smegmatis str. MC2 155] gi|118169688|gb|ABK70584.1| metallo-beta-lactamase family protein [Mycobacterium smegmatis str. MC2 155] Length=371 Score = 480 bits (1235), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 250/374 (67%), Positives = 292/374 (79%), Gaps = 5/374 (1%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 M+R ALRL +A L AG WLL AL GT A++GA I+ V+ +SP + FVN++PA Sbjct 1 MLRAALRLTTRSAGLLAGGWLLGALRGTYASVGAQPRDIKPVATRSPQFDGKVFVNIEPA 60 Query 61 S-MFTLDREELRLIVWELVARHSASRPAAPIPLASP-NIYRGDASRLAVSWFGHSTALLE 118 S LDREE R + E+ AS P IPLA P +A AVSW+GHS+AL+E Sbjct 61 SPGINLDREERRRLFAEMFGSKGASWPPGEIPLAEPTEAETAEAKPCAVSWYGHSSALIE 120 Query 119 IDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVA 178 +DGYRVLTDP+WSDRCSPS VVGP+RLH PPV L ALPAVDAVVISHDHYDHLDIDTV Sbjct 121 VDGYRVLTDPIWSDRCSPSRVVGPRRLHAPPVPLEALPAVDAVVISHDHYDHLDIDTVRG 180 Query 179 LVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSR 238 L QRAPFLVPLG+GAHLR WG+P+ RIVELDWN+S ++ +LT+VC PARHFSGRFL R Sbjct 181 LARTQRAPFLVPLGIGAHLRKWGIPEARIVELDWNESHRIGDLTIVCAPARHFSGRFLQR 240 Query 239 NTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNP 298 NTTLWASW +GP HRA+FGGDTGYTKSF++IG++HGPFDLTLLP+GAYN WPDIHMNP Sbjct 241 NTTLWASWVVIGPGHRAFFGGDTGYTKSFSEIGSEHGPFDLTLLPVGAYNPGWPDIHMNP 300 Query 299 EEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRV 358 EE+VRAHLD+T+ SG+LVP+HW TFRLAPHPW EPV RLLAAA+P V VAVP PGQRV Sbjct 301 EESVRAHLDMTE--SGLLVPIHWATFRLAPHPWAEPVRRLLAAADPAGVQVAVPKPGQRV 358 Query 359 DPTGPMRLHPWWRL 372 D P+ L PWW+L Sbjct 359 DGGSPV-LDPWWQL 371 >gi|333989469|ref|YP_004522083.1| hypothetical protein JDM601_0829 [Mycobacterium sp. JDM601] gi|333485437|gb|AEF34829.1| conserved hypothetical protein [Mycobacterium sp. JDM601] Length=386 Score = 479 bits (1234), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 243/370 (66%), Positives = 283/370 (77%), Gaps = 22/370 (5%) Query 20 WLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVA 79 W LRAL GTP ALGA +I AV+ +S +YRDG F N++ ASM +DRE+ RL++ EL A Sbjct 20 WTLRALRGTPGALGAAPHAIDAVAARSRHYRDGIFHNVERASMVNMDREQQRLMLRELFA 79 Query 80 RHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDV 139 ASRP AP+PL P+ + A L V+W GH+TAL+E+DGYRVLTDPVWS+RCSPSD Sbjct 80 DRGASRPVAPVPLGVPD-FADAAEPLTVTWLGHATALIEVDGYRVLTDPVWSERCSPSDA 138 Query 140 VGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRS 199 VGP+RLHPPPV+L+ALPAVDA+VISHDHYDHLDIDTV AL QRAPF+VPLGVGAHLR+ Sbjct 139 VGPRRLHPPPVELSALPAVDAIVISHDHYDHLDIDTVTALARSQRAPFVVPLGVGAHLRA 198 Query 200 WGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGG 259 WG+P DR+VELDW++ A ELT+VC PARHFSGRFL+RN TLWASW GP+HR YFGG Sbjct 199 WGIPADRVVELDWDEQASFGELTLVCTPARHFSGRFLTRNMTLWASWVIAGPDHRVYFGG 258 Query 260 DTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPV 319 D+GYT SF QIGAD+GPFD+TLLPIGAYNTAWPD+HMNPEEAVRAHLDV LVP+ Sbjct 259 DSGYTGSFGQIGADYGPFDVTLLPIGAYNTAWPDVHMNPEEAVRAHLDVD---GATLVPI 315 Query 320 HWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRV-------------DPTGPMR- 365 HW TFRLAPH W EPVERLLAAAEP V+V VP PG V P+ +R Sbjct 316 HWCTFRLAPHRWEEPVERLLAAAEPAGVSVVVPRPGGSVRLDGGEAKLGPPHKPSERIRP 375 Query 366 ----LHPWWR 371 + PWWR Sbjct 376 AAGDIEPWWR 385 >gi|145222346|ref|YP_001133024.1| beta-lactamase domain-containing protein [Mycobacterium gilvum PYR-GCK] gi|315442779|ref|YP_004075658.1| Zn-dependent hydrolase of beta-lactamase fold protein [Mycobacterium sp. Spyr1] gi|145214832|gb|ABP44236.1| beta-lactamase domain protein [Mycobacterium gilvum PYR-GCK] gi|315261082|gb|ADT97823.1| predicted Zn-dependent hydrolase of beta-lactamase fold protein [Mycobacterium sp. Spyr1] Length=372 Score = 477 bits (1228), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 234/372 (63%), Positives = 285/372 (77%), Gaps = 3/372 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 +VR ALR GT SL AG W+LRALHGTPA+LGA A I V+ +SP+Y+DG FVNL+ + Sbjct 2 VVRTALRFGFGTTSLLAGGWVLRALHGTPASLGATPAEIAPVARRSPHYKDGRFVNLESS 61 Query 61 SM-FTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEI 119 S +DRE R ++ +L SA +P PIPL P + A SW+GHS+AL+E+ Sbjct 62 SSGLPMDRELQRKLLRDLANAGSAGKPPRPIPLKEPPTVEPTGADAAASWYGHSSALIEV 121 Query 120 DGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVAL 179 DGYRVL DPVWS+RCSPS VGPQR+H P+ L +LPAVDAVVISHDHYDHLDIDT++AL Sbjct 122 DGYRVLVDPVWSERCSPSRTVGPQRMHDVPLLLESLPAVDAVVISHDHYDHLDIDTIIAL 181 Query 180 VGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRN 239 QRAPF+VPLG+GAHLR WG+P RIVELDW++ ++ +LT++C PARHFSGR SR+ Sbjct 182 ARTQRAPFVVPLGIGAHLRKWGIPSRRIVELDWHEGHRIGDLTLICTPARHFSGRLFSRD 241 Query 240 TTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPE 299 TTLWASW GP+H+A+FGGDTGYTKSF IGA +GPFDLTL+PIGAY+ A+ DIHMNPE Sbjct 242 TTLWASWVITGPSHKAFFGGDTGYTKSFADIGAQYGPFDLTLMPIGAYHPAFADIHMNPE 301 Query 300 EAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVD 359 EAVRAHLD+ D + +LVPVHW TFRLAPHPW EPVERL+ AAE + V +AVP+PG+RV Sbjct 302 EAVRAHLDLADPDASVLVPVHWATFRLAPHPWAEPVERLVTAAELDGVRLAVPIPGERVL 361 Query 360 PTGPMRLHPWWR 371 P PWWR Sbjct 362 PGS--TFEPWWR 371 >gi|169628057|ref|YP_001701706.1| hypothetical protein MAB_0960 [Mycobacterium abscessus ATCC 19977] gi|169240024|emb|CAM61052.1| Conserved hypothetical protein [Mycobacterium abscessus] Length=366 Score = 441 bits (1135), Expect = 8e-122, Method: Compositional matrix adjust. Identities = 220/369 (60%), Positives = 266/369 (73%), Gaps = 5/369 (1%) Query 4 RALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMF 63 RAL + AG A A TW+ RAL P LGA I V++ SP YR G F N +PA F Sbjct 2 RALWVGAGAA--IASTWIGRALRDVPQTLGASKGRIAEVAKGSPQYRGGTFHNAEPARQF 59 Query 64 TLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYR 123 + D E +VW+++ R P +PLA P + G + LA +WFGHS+ L+EIDGYR Sbjct 60 SPD-AETTTVVWDVLTRRGVGTPKGQVPLAVPEL-SGPPADLAATWFGHSSVLVEIDGYR 117 Query 124 VLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQ 183 VLTDPVWSDRCSPS VVGP R HP PV+L+ALPA+DAVVISHDHYDHLD+D+++AL Q Sbjct 118 VLTDPVWSDRCSPSRVVGPHRQHPVPVELSALPALDAVVISHDHYDHLDMDSIIALTRSQ 177 Query 184 RAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLW 243 A F+VPLGVGAHLR WGV R++ELDW+QS Q+ +LT+ C ARHFSGR ++RNTTLW Sbjct 178 NAVFVVPLGVGAHLRGWGVSPARVIELDWDQSHQLGKLTLTCTQARHFSGRSITRNTTLW 237 Query 244 ASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVR 303 ASWAF GP H+ +FGGDTGYTK+F IG +GPFDLTLLP+GAYNT+W DIHMNPEEAV+ Sbjct 238 ASWAFAGPKHKVFFGGDTGYTKAFKVIGDTYGPFDLTLLPVGAYNTSWADIHMNPEEAVQ 297 Query 304 AHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGP 363 HLD+ + L+P+HW TF LA HPW EP+ER+LAAAE + VTV P PGQR D P Sbjct 298 THLDLA-TAQAPLLPIHWATFNLALHPWAEPIERVLAAAEEQGVTVVAPRPGQRADARQP 356 Query 364 MRLHPWWRL 372 WWRL Sbjct 357 AAPDGWWRL 365 >gi|111022001|ref|YP_704973.1| hypothetical protein RHA1_ro05034 [Rhodococcus jostii RHA1] gi|110821531|gb|ABG96815.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=365 Score = 408 bits (1049), Expect = 6e-112, Method: Compositional matrix adjust. Identities = 204/357 (58%), Positives = 253/357 (71%), Gaps = 5/357 (1%) Query 16 AAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVW 75 AA WL RA G P+ +GA A +R + SP YRD F N DP+S E IV Sbjct 8 AALGWLTRAAWGLPSQIGASRAKVRPYAATSPRYRDRQFHNTDPSSTMMPGSETG--IVK 65 Query 76 ELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCS 135 L+ R +A RP PIPLA+P + +A+ +AV+W+GHS+ L+E+DGYRVL DPVWSDR S Sbjct 66 ALITRGAAGRPRRPIPLATP-LAPVEAADVAVTWYGHSSVLVEVDGYRVLADPVWSDRVS 124 Query 136 PSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGA 195 PS ++GP R+HP PV LA LP +DA+VISHDHYDHLD+ TV L Q+APF+VP+G+GA Sbjct 125 PSAILGPSRMHPTPVPLADLPVLDAIVISHDHYDHLDMATVQQLAATQKAPFVVPVGLGA 184 Query 196 HLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRA 255 HLR W VP++RIVELDW++S + +LT+ C ARHFSGR L RNTT WASW GPN + Sbjct 185 HLRQWRVPEERIVELDWDESTTLGDLTLTCTEARHFSGRGLVRNTTQWASWVLAGPNRKV 244 Query 256 YFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DSGS 313 +FGGD+GYT F +G +GPFDLTLLP+GAY+T W DIHMNPEEAV+ H D+ D+ Sbjct 245 FFGGDSGYTPRFADLGRRYGPFDLTLLPVGAYDTRWADIHMNPEEAVQTHADLNAGDARR 304 Query 314 GMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 G+LVPVHW TF LA H W EP+ RLLAAA+ + VAVP+PGQRVD P PWW Sbjct 305 GLLVPVHWATFNLAFHSWSEPIVRLLAAAQEKGTPVAVPMPGQRVDALKPTAQTPWW 361 >gi|226364508|ref|YP_002782290.1| hypothetical protein ROP_50980 [Rhodococcus opacus B4] gi|226242997|dbj|BAH53345.1| hypothetical protein [Rhodococcus opacus B4] Length=371 Score = 407 bits (1045), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 203/357 (57%), Positives = 253/357 (71%), Gaps = 5/357 (1%) Query 16 AAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVW 75 AA WL RA G P+ +GA A +R + SP YR+ F N DP+SM E I+ Sbjct 14 AALGWLTRAAWGLPSQIGASRAKVRPYAATSPRYRNRQFHNTDPSSMMLPGSETG--ILK 71 Query 76 ELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCS 135 L+ R A RP PIPLA+P + +A+ +AV+W+GHS+ L+E+DGYRVL DPVWS R S Sbjct 72 ALITRGKAGRPRRPIPLATP-LAPVEAADVAVTWYGHSSVLVEVDGYRVLADPVWSRRVS 130 Query 136 PSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGA 195 PS ++GP R+HP PV LA LP +DA+VISHDHYDHLD+ TV L Q+APF+VP+G+GA Sbjct 131 PSALLGPSRMHPTPVPLADLPVLDAIVISHDHYDHLDMATVQQLAATQKAPFVVPVGLGA 190 Query 196 HLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRA 255 HLR W VP++RIVELDW++S + ELT+ C ARHFSGR L RNTT WASW GP+ + Sbjct 191 HLRHWRVPEERIVELDWDESTTLGELTLTCTEARHFSGRGLVRNTTQWASWVLAGPSRKV 250 Query 256 YFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DSGS 313 +FGGD+GYT F ++G +GPFDLTLLP+GAY+T W DIHMNPEEAV+ H D+ D+G Sbjct 251 FFGGDSGYTPRFAELGRRYGPFDLTLLPVGAYDTRWADIHMNPEEAVQTHADLNAGDAGR 310 Query 314 GMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 G+LVPVHW TF LA H W EP+ RLLAAA+ VAVP+PGQRVD P PWW Sbjct 311 GLLVPVHWATFNLAFHTWSEPIVRLLAAAQEAGTPVAVPMPGQRVDALKPAAQTPWW 367 >gi|289442317|ref|ZP_06432061.1| LOW QUALITY PROTEIN: conserved hypothetical protein [Mycobacterium tuberculosis T46] gi|289749429|ref|ZP_06508807.1| LOW QUALITY PROTEIN: conserved hypothetical protein [Mycobacterium tuberculosis T92] gi|289415236|gb|EFD12476.1| LOW QUALITY PROTEIN: conserved hypothetical protein [Mycobacterium tuberculosis T46] gi|289690016|gb|EFD57445.1| LOW QUALITY PROTEIN: conserved hypothetical protein [Mycobacterium tuberculosis T92] Length=189 Score = 389 bits (998), Expect = 5e-106, Method: Compositional matrix adjust. Identities = 189/189 (100%), Positives = 189/189 (100%), Gaps = 0/189 (0%) Query 184 RAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLW 243 RAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLW Sbjct 1 RAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLW 60 Query 244 ASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVR 303 ASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVR Sbjct 61 ASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVR 120 Query 304 AHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGP 363 AHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGP Sbjct 121 AHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGP 180 Query 364 MRLHPWWRL 372 MRLHPWWRL Sbjct 181 MRLHPWWRL 189 >gi|284988838|ref|YP_003407392.1| beta-lactamase domain-containing protein [Geodermatophilus obscurus DSM 43160] gi|284062083|gb|ADB73021.1| beta-lactamase domain protein [Geodermatophilus obscurus DSM 43160] Length=409 Score = 388 bits (997), Expect = 8e-106, Method: Compositional matrix adjust. Identities = 205/351 (59%), Positives = 242/351 (69%), Gaps = 5/351 (1%) Query 20 WLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVA 79 W+ RA G P ALGA ++A + SP + +G F N + L+ Sbjct 27 WVARAAWGLPTALGAGQREVQASAAGSPQFAEGRFHNRLSTPARPPANAQRGLLRQMHEE 86 Query 80 RHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDV 139 RH+ PA PIPL P + +A+ LAV+WFGHS+ALLE+DG RVL DPVW +R SPS + Sbjct 87 RHTG-LPARPIPLVRPELP-AEAAELAVTWFGHSSALLEVDGRRVLVDPVWGERVSPSPL 144 Query 140 VGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRS 199 VGP RLHP P+ L LP VDAV++SHDHYDHLD+ TV AL+ Q APF+VPLG+GAHLR Sbjct 145 VGPTRLHPAPLPLEDLPQVDAVLVSHDHYDHLDLPTVRALLRSQSAPFVVPLGLGAHLRG 204 Query 200 WGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGG 259 WGVP++R+VELDW+ + V LT+ C ARHFSGRFL+R+TTLWASW GP HR +FGG Sbjct 205 WGVPEERVVELDWDGAVDVAGLTLTCTEARHFSGRFLTRDTTLWASWVVAGPRHRVFFGG 264 Query 260 DTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPV 319 DTGYT +F QIGA GPFDLTLLPIGAYN AW IHM PEEAVRAH D+ G G+LVPV Sbjct 265 DTGYTPAFAQIGALQGPFDLTLLPIGAYNDAWALIHMTPEEAVRAHGDL---GGGLLVPV 321 Query 320 HWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 HW TF LA H W EPV+RL AAAE VAVP PGQRVD P L WW Sbjct 322 HWATFNLAFHRWAEPVQRLCAAAERSEARVAVPRPGQRVDVLAPPPLTDWW 372 >gi|226308026|ref|YP_002767986.1| hypothetical protein RER_45390 [Rhodococcus erythropolis PR4] gi|226187143|dbj|BAH35247.1| conserved hypothetical protein [Rhodococcus erythropolis PR4] Length=371 Score = 387 bits (995), Expect = 1e-105, Method: Compositional matrix adjust. Identities = 189/350 (54%), Positives = 236/350 (68%), Gaps = 5/350 (1%) Query 23 RALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHS 82 RA G P +GA +++ + SP YRD F N +P+S + + R S Sbjct 21 RAAWGIPTQIGASRNTVQPYAAMSPRYRDRQFHNSEPSSTLVPGTDAGMFK--SMATRGS 78 Query 83 ASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGP 142 RP PIPLA+P + A AV+W+GHS+ L+E+DGYRVL DPVWS+R SPS VGP Sbjct 79 TGRPRQPIPLATP-LAPSVAGDAAVTWYGHSSVLVEVDGYRVLADPVWSERVSPSATVGP 137 Query 143 QRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGV 202 R+HP PV LA LP VDA+VISHDHYDHLD+ TV L Q APF+VP+G+GAHLR W V Sbjct 138 ARMHPTPVALADLPTVDAIVISHDHYDHLDMATVKILTRTQTAPFVVPIGIGAHLRHWKV 197 Query 203 PQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTG 262 P++RIVELDW++S ++D+L + C ARHFSGR L RNTT WASW F GP HR +FGGD+G Sbjct 198 PENRIVELDWDESTKIDDLVLTCTEARHFSGRGLVRNTTQWASWVFAGPKHRVFFGGDSG 257 Query 263 YTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DSGSGMLVPVH 320 YT F Q+G +GPFDLTLLP+GAY+ WPDIHMNPEEAV+ H+D+ D G+ VP+H Sbjct 258 YTSRFEQLGETYGPFDLTLLPVGAYDVRWPDIHMNPEEAVQTHIDLNKGDGSRGVFVPIH 317 Query 321 WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 W TF LA H W EP+ RL +A TV+VP+PG R+D P WW Sbjct 318 WATFNLAFHSWSEPIIRLNESAAEAGTTVSVPMPGGRIDALSPTPSSKWW 367 >gi|54022642|ref|YP_116884.1| hypothetical protein nfa6750 [Nocardia farcinica IFM 10152] gi|54014150|dbj|BAD55520.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=381 Score = 384 bits (987), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 200/355 (57%), Positives = 239/355 (68%), Gaps = 16/355 (4%) Query 29 PAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLI-VWELVARHSASRPA 87 P+ALGA ++IR + NYR G F N +P+ F L+ W + A P Sbjct 28 PSALGASMSTIRPSARSLANYRGGRFHNTEPSVQFEAGSVAALLVSAW---TKRKAGHPR 84 Query 88 APIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHP 147 PIP+ P + LAV+W+GH+T L+E+DGYRVLTDPVWS+R SPS +VGP RLHP Sbjct 85 GPIPVVRPET-PAEPGDLAVTWYGHATTLVEVDGYRVLTDPVWSERVSPSTLVGPARLHP 143 Query 148 PPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRI 207 P L+ALP +DAV+ISHDHYDHLD +TV AL+ Q APF+VP+G+GAHLR WGVP+DRI Sbjct 144 VPQPLSALPELDAVLISHDHYDHLDKETVRALLAGQSAPFVVPVGIGAHLRHWGVPEDRI 203 Query 208 VELDWNQSAQVD---------ELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFG 258 VEL W S + +L + C ARHFSGR L RNTTLWASW+ VGP R YFG Sbjct 204 VELGWGASVSMQALGRARDGGDLVLTCTEARHFSGRGLVRNTTLWASWSIVGPTRRVYFG 263 Query 259 GDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLD--VTDSGSGML 316 GDTGYTK+F + GA GPFDLTLLPIGAY+ W D+HMNPEEAVRAH D V D+G GML Sbjct 264 GDTGYTKAFAEAGAALGPFDLTLLPIGAYDEHWTDVHMNPEEAVRAHADLCVGDAGHGML 323 Query 317 VPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 VP+HW TF LA H W EPV R+++AA VAVP PGQRV P G PWW Sbjct 324 VPIHWATFNLAFHGWSEPVRRMVSAARAAGTRVAVPKPGQRVLPAGAAEPDPWWE 378 >gi|331697770|ref|YP_004334009.1| beta-lactamase domain-containing protein [Pseudonocardia dioxanivorans CB1190] gi|326952459|gb|AEA26156.1| beta-lactamase domain protein [Pseudonocardia dioxanivorans CB1190] Length=372 Score = 379 bits (972), Expect = 5e-103, Method: Compositional matrix adjust. Identities = 209/375 (56%), Positives = 256/375 (69%), Gaps = 12/375 (3%) Query 1 MVRRALRLAA-----GTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFV 55 M RR + AA G + AG + RA G P A+GA A +RA + SP+ RDG F Sbjct 1 MSRRVVSAAARSVLVGGLLVGAGR-VARAARGVPLAVGASDAVLRARAASSPHSRDGRFG 59 Query 56 NLDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTA 115 N +P ELR ++ L+ R + P+AP+P+A+ ++ A LA++W+GHS+ Sbjct 60 NTEPGVQIAPG--ELRGLLLRLLTRGTTGTPSAPVPIAA-DVQPVTAGELALTWYGHSSV 116 Query 116 LLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDT 175 LLEIDG RVLTDPVWS+R SPS+ VGP+RLHP PV L ALP VDAVV+SHDHYDHLD+ T Sbjct 117 LLEIDGRRVLTDPVWSERVSPSERVGPRRLHPAPVPLQALPQVDAVVVSHDHYDHLDMAT 176 Query 176 VVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRF 235 V L A F+VP+G+GAHLR WGVP DRI ELDWN + +V LT+ C ARHFSGR Sbjct 177 VRRLGHETAAVFVVPVGIGAHLRRWGVPDDRIRELDWNDATEVAGLTITCAEARHFSGRL 236 Query 236 LSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIH 295 +RNTT W+SWA GP RAYFGGDTGYT +F++ GA GPFD+T+LP+GAY+ AWPDIH Sbjct 237 FARNTTQWSSWAVAGPRRRAYFGGDTGYTAAFSEAGARLGPFDVTVLPVGAYDVAWPDIH 296 Query 296 MNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPG 355 MNPEE+VRAH D+ G+LVPVHW TF LA H W EPV RL AAAE + + VP PG Sbjct 297 MNPEESVRAHRDLR---GGLLVPVHWATFNLAFHGWSEPVTRLRAAAETARIPLVVPRPG 353 Query 356 QRVDPTGPMRLHPWW 370 QRVD P L WW Sbjct 354 QRVDLLVPPALDDWW 368 >gi|325676219|ref|ZP_08155899.1| multidrug resistance protein RomA [Rhodococcus equi ATCC 33707] gi|325553003|gb|EGD22685.1| multidrug resistance protein RomA [Rhodococcus equi ATCC 33707] Length=369 Score = 379 bits (972), Expect = 6e-103, Method: Compositional matrix adjust. Identities = 197/345 (58%), Positives = 237/345 (69%), Gaps = 6/345 (1%) Query 27 GTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRP 86 GT ALGA A+I +E SP YRD F N DP+S +L + + R RP Sbjct 28 GTLPALGASRAAIEPYAESSPRYRDSRFHNSDPSS--SLPAGSQSGLAKAFLTRGDVGRP 85 Query 87 AAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLH 146 IPLA+P + +A LAV+WFGHS+ LLEIDG RVL DPVWS+R SPS VVGP R+H Sbjct 86 RRAIPLATP-LAPAEAGELAVTWFGHSSVLLEIDGRRVLADPVWSERVSPSAVVGPARMH 144 Query 147 PPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDR 206 P P+ LA LP +DAVVISHDHYDHLD TV L Q F+VP+GVGAHLR W VP DR Sbjct 145 PVPMALADLPPIDAVVISHDHYDHLDQATVTGLARTQDTVFVVPIGVGAHLRRWNVPSDR 204 Query 207 IVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKS 266 IVELDW++SA+V+ L + C ARHFSGR L+R+TTLW+SW GP HR +FGGD+GYT Sbjct 205 IVELDWDESAEVNGLVLTCTEARHFSGRGLARDTTLWSSWVIAGPRHRVFFGGDSGYTPR 264 Query 267 FTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRL 326 F +G +GPFD+TLLP+GAY+ WPDIHMNPEEAVR HLDV +L+P+HW TF L Sbjct 265 FADLGRAYGPFDVTLLPVGAYDERWPDIHMNPEEAVRTHLDV---AGALLIPIHWATFNL 321 Query 327 APHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 A HPWGEP+ RL+ AA V +A+P+ GQRVD P PWW Sbjct 322 AFHPWGEPITRLVDAATAAEVAMAIPMVGQRVDALRPPEQKPWWE 366 >gi|289752962|ref|ZP_06512340.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] gi|289693549|gb|EFD60978.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] Length=184 Score = 378 bits (971), Expect = 8e-103, Method: Compositional matrix adjust. Identities = 183/184 (99%), Positives = 184/184 (100%), Gaps = 0/184 (0%) Query 189 VPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAF 248 +PLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAF Sbjct 1 MPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAF 60 Query 249 VGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDV 308 VGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDV Sbjct 61 VGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDV 120 Query 309 TDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHP 368 TDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHP Sbjct 121 TDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHP 180 Query 369 WWRL 372 WWRL Sbjct 181 WWRL 184 >gi|312138495|ref|YP_004005831.1| metallo-beta-lactamase superfamily protein [Rhodococcus equi 103S] gi|311887834|emb|CBH47146.1| putative secreted metallo-beta-lactamase superfamily protein [Rhodococcus equi 103S] Length=369 Score = 376 bits (965), Expect = 4e-102, Method: Compositional matrix adjust. Identities = 196/345 (57%), Positives = 236/345 (69%), Gaps = 6/345 (1%) Query 27 GTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRP 86 GT ALGA A+I +E SP YRD F N DP+S +L + + R RP Sbjct 28 GTLPALGASRAAIEPYAESSPRYRDSRFHNSDPSS--SLPAGSQSGLAKAFLTRGDVGRP 85 Query 87 AAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLH 146 IPLA+P + +A LAV+WFGHS+ LLEIDG RVL DPVWS+R SPS VVGP R+H Sbjct 86 RRAIPLATP-LAPAEAGELAVTWFGHSSVLLEIDGRRVLADPVWSERVSPSAVVGPARMH 144 Query 147 PPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDR 206 P P+ LA LP +DAVVISHDHYDHLD TV L Q F+VP+GVGAHLR W VP DR Sbjct 145 PVPMALADLPPIDAVVISHDHYDHLDQATVTGLARTQDTVFVVPIGVGAHLRRWNVPSDR 204 Query 207 IVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKS 266 IVELDW++SA+V+ L + C ARHFSGR L+R+TTLW+SW GP HR +F GD+GYT Sbjct 205 IVELDWDESAEVNGLVLTCTEARHFSGRGLARDTTLWSSWVIAGPRHRVFFEGDSGYTPR 264 Query 267 FTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRL 326 F +G +GPFD+TLLP+GAY+ WPDIHMNPEEAVR HLDV +L+P+HW TF L Sbjct 265 FADLGRAYGPFDVTLLPVGAYDERWPDIHMNPEEAVRTHLDV---AGALLIPIHWATFNL 321 Query 327 APHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 A HPWGEP+ RL+ AA V +A+P+ GQRVD P PWW Sbjct 322 AFHPWGEPITRLVDAATAAEVAMAIPMVGQRVDALRPPEQKPWWE 366 >gi|229488966|ref|ZP_04382832.1| metallo-beta-lactamase family protein [Rhodococcus erythropolis SK121] gi|229324470|gb|EEN90225.1| metallo-beta-lactamase family protein [Rhodococcus erythropolis SK121] Length=371 Score = 375 bits (963), Expect = 7e-102, Method: Compositional matrix adjust. Identities = 190/350 (55%), Positives = 238/350 (68%), Gaps = 5/350 (1%) Query 23 RALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHS 82 RA G P +GA ++++ + SP YRD F N +P+S TL + + R S Sbjct 21 RAAWGIPTQIGASRSTVQPYAAMSPRYRDRQFHNSEPSS--TLVPGTDVGMFKSMATRGS 78 Query 83 ASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGP 142 RP PIPLA+ + A AV+W+GHS+ L+E+DGYRVL DPVWS+R SPS VGP Sbjct 79 TGRPRQPIPLAT-PLAPAAAGDAAVTWYGHSSVLVEVDGYRVLADPVWSERVSPSATVGP 137 Query 143 QRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGV 202 R+HP PV L LPAVDA+VISHDHYDHLD+ TV L Q APF+VP+G+GAHLR W V Sbjct 138 ARMHPTPVALTELPAVDAIVISHDHYDHLDMATVKTLTRTQTAPFVVPIGIGAHLRHWKV 197 Query 203 PQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTG 262 P++RIVELDW++S ++D+L + C ARHFSGR L RNTT WASW F GP HR +FGGD+G Sbjct 198 PENRIVELDWDESTKIDDLVLTCTEARHFSGRGLVRNTTQWASWVFAGPKHRVFFGGDSG 257 Query 263 YTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DSGSGMLVPVH 320 YT F Q+G +GPFDLTLLP+GAY+ WPDIHMNPEEAV+ H+D+ D G+ VP+H Sbjct 258 YTSRFEQLGETYGPFDLTLLPVGAYDVRWPDIHMNPEEAVQTHIDLNKGDGSRGVFVPIH 317 Query 321 WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 W TF LA H W EP+ RL +A TV+VP+PG R+D P WW Sbjct 318 WATFNLAFHSWSEPIIRLDESAADAGTTVSVPMPGGRIDALSPTPPSKWW 367 >gi|333918536|ref|YP_004492117.1| hypothetical protein AS9A_0865 [Amycolicicoccus subflavus DQS3-9A1] gi|333480757|gb|AEF39317.1| hypothetical protein AS9A_0865 [Amycolicicoccus subflavus DQS3-9A1] Length=368 Score = 374 bits (959), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 186/341 (55%), Positives = 237/341 (70%), Gaps = 4/341 (1%) Query 31 ALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPAAPI 90 A+GA + IR SPN+ +G F N +PA F+ R+ L + +V R + PA + Sbjct 27 AIGAPRSRIRPYVAGSPNFSNGTFRNAEPAVPFS-PRQAPDLF-FSIVLRGNTGAPARQV 84 Query 91 PLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPV 150 PLA P + A LA +WFGHS+ L+E+DG+RVLTDPVWS+R SPS +GP+R+HP PV Sbjct 85 PLAVP-LAPASAGELAAAWFGHSSVLVEVDGHRVLTDPVWSERVSPSQRLGPRRMHPVPV 143 Query 151 QLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVEL 210 +++ LP VDAVVISHDHYDHLD T+ LV +Q APF+VPLG+G HLRSWGVP+ RI+EL Sbjct 144 KISQLPQVDAVVISHDHYDHLDQRTISDLVRLQAAPFVVPLGIGGHLRSWGVPERRIIEL 203 Query 211 DWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQI 270 DW + V ELT+ C PARHFSGR +SRN TLWASW GP +FGGD+GYT SF ++ Sbjct 204 DWGEETAVGELTISCAPARHFSGRGISRNVTLWASWVLRGPRRSVFFGGDSGYTDSFAEL 263 Query 271 GADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGS-GMLVPVHWGTFRLAPH 329 G HGPFDLTLLPIGAY+ WPD+HM PEEAV+ H + + S G+++P+HWGTF L H Sbjct 264 GNRHGPFDLTLLPIGAYSDQWPDVHMTPEEAVQTHCVLNGTPSAGVMMPIHWGTFNLGFH 323 Query 330 PWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 W EP+ RL A E V A P+PGQR+D P+ + WW Sbjct 324 SWMEPIVRLTRAKEAHGVRTAAPMPGQRIDFLKPLPRNEWW 364 >gi|258650385|ref|YP_003199541.1| beta-lactamase fold-like Zn-dependent hydrolase [Nakamurella multipartita DSM 44233] gi|258553610|gb|ACV76552.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Nakamurella multipartita DSM 44233] Length=353 Score = 369 bits (946), Expect = 6e-100, Method: Compositional matrix adjust. Identities = 194/350 (56%), Positives = 236/350 (68%), Gaps = 9/350 (2%) Query 21 LLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVAR 80 L RA G P A+GA IR V+E S + +F N++PA +F L R+ LRL+ EL+ R Sbjct 8 LGRAARGLPTAIGAGPDEIRPVAEGSSRFDGTSFSNVEPAHVFGL-RQGLRLLP-ELL-R 64 Query 81 HSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVV 140 H P IPL + A LAV+W GH+T L+E+DG+ VLTDPVWS R SPS + Sbjct 65 HRNGHPPMTIPLVTAPPA-SQAGELAVTWLGHATTLVELDGHFVLTDPVWSQRVSPSATI 123 Query 141 GPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSW 200 GP RLHP P+ LA LPA+ AVVISHDHYDHLD+ T+ LV Q APF+VPLGVGAHLR W Sbjct 124 GPARLHPMPIALAQLPALSAVVISHDHYDHLDLPTIRTLVSTQTAPFVVPLGVGAHLRGW 183 Query 201 GVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGD 260 GVP+DRIVELDW +S V +L +VC P RHFSGR L RNTTLW+SWA +GP HR YFGGD Sbjct 184 GVPEDRIVELDWTRSTTVGDLEIVCTPGRHFSGRGLRRNTTLWSSWALLGPQHRVYFGGD 243 Query 261 TGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVH 320 TGYT +F I GPFD+T+LPIGAY WPDIH++PEEA AH D+ G +++P+H Sbjct 244 TGYTTAFADIARQWGPFDVTILPIGAYGDQWPDIHLHPEEAATAHRDL---GGALMIPIH 300 Query 321 WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWW 370 W TF LA H W EP+ RL AA + +A P PG+RV P WW Sbjct 301 WATFDLALHSWAEPMHRLRAAG--TDIRIAAPRPGERVVPNDITTTDGWW 348 >gi|238063763|ref|ZP_04608472.1| zinc-dependent hydrolase [Micromonospora sp. ATCC 39149] gi|237885574|gb|EEP74402.1| zinc-dependent hydrolase [Micromonospora sp. ATCC 39149] Length=369 Score = 363 bits (933), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 200/375 (54%), Positives = 249/375 (67%), Gaps = 13/375 (3%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAV-SEQSPNYRDGAFVNLDP 59 M RR LR A G A+LA W +R + PAALG RA + +SP +RDG F N Sbjct 1 MARR-LRGAVGFAALAGLAWAVRDV---PAALGGRITGARAERAARSPQFRDGIFHNR-- 54 Query 60 ASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDAS---RLAVSWFGHSTAL 116 AS T+ R +V EL+ RP+ +PL P A+ L V W+GH++AL Sbjct 55 ASTRTMAGAPDRSLVRELIFGKQKRRPSVAVPLLRPADSPATAATERELGVVWYGHASAL 114 Query 117 LEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTV 176 +EI+G+RVL DPVWSDRCSPS +VGP RLH PPV L LPAVDA+VISHDHYDHLD+ TV Sbjct 115 IEIEGHRVLVDPVWSDRCSPSALVGPHRLHEPPVGLHELPAVDAIVISHDHYDHLDMATV 174 Query 177 VALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFL 236 AL Q APFLVPLGVGAHL WGVP+ RI+ELDW++S +V LT+ A+HFSGR L Sbjct 175 RALTAGQSAPFLVPLGVGAHLDRWGVPEQRIIELDWSESHRVGGLTITATAAQHFSGRGL 234 Query 237 SRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHM 296 R+ TLW+SW G + + ++ GD+GY + +IGA+HGPFD+TL+ IGAY+ AWP IHM Sbjct 235 RRDGTLWSSWVVAGVHRKVFYTGDSGYFDGYAEIGAEHGPFDVTLMQIGAYDRAWPSIHM 294 Query 297 NPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQ 356 PEEAV AHLDV G+L+PVHW TF LA H W EPV+RL A A+ V +AVP PG+ Sbjct 295 FPEEAVTAHLDVR---GGLLLPVHWATFNLALHDWSEPVDRLWAEAKARDVRLAVPRPGE 351 Query 357 RVDPTGPMRLHPWWR 371 RV P + WW+ Sbjct 352 RVVVDAPPPVDGWWQ 366 >gi|311899072|dbj|BAJ31480.1| hypothetical protein KSE_57070 [Kitasatospora setae KM-6054] Length=376 Score = 358 bits (919), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 186/330 (57%), Positives = 228/330 (70%), Gaps = 11/330 (3%) Query 46 SPNYRDGAFVN----LDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGD 101 SP YRDG F N + + D LR +++E R P P+PLA P + G Sbjct 51 SPQYRDGVFHNAPSEVSAGAPGRPDGATLRRMLFEKEGR----VPDGPVPLAVPEVADGA 106 Query 102 ASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAV 161 + +AV+WFGH++ALLE+DG RVL DP+WSDRCSPS + GP+RLHP PV+LA LP VDAV Sbjct 107 SRGVAVTWFGHASALLELDGCRVLVDPIWSDRCSPSQLTGPKRLHPVPVELAELPQVDAV 166 Query 162 VISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDEL 221 +ISHDHYDHLD+ TV LV +Q APF VPLG+G HLR WGVP+ RI+ELDW+++ + EL Sbjct 167 LISHDHYDHLDMATVRRLVELQSAPFAVPLGIGGHLRRWGVPEHRIIELDWDETCTLGEL 226 Query 222 TVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTL 281 T+ A HFSGR L RNTTLW SW GP R +F GD+GY + F +IG HGPFD L Sbjct 227 TLTLTAAHHFSGRSLVRNTTLWGSWVVAGPERRVFFTGDSGYFEGFARIGELHGPFDAAL 286 Query 282 LPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAA 341 + IGAY+ AW DIH+NPEEAVRAHLD+ G+L+P+HW TF LAPH W EPVERLLA Sbjct 287 MAIGAYDPAWADIHLNPEEAVRAHLDLR---GGLLLPIHWCTFNLAPHRWAEPVERLLAE 343 Query 342 AEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 A+ + V VAVP PGQRV+ P WW Sbjct 344 AKQQGVPVAVPRPGQRVETANPPEPDGWWE 373 >gi|257055482|ref|YP_003133314.1| putative Zn-dependent hydrolase of beta-lactamase fold protein [Saccharomonospora viridis DSM 43017] gi|256585354|gb|ACU96487.1| predicted Zn-dependent hydrolase of beta-lactamase fold protein [Saccharomonospora viridis DSM 43017] Length=365 Score = 357 bits (916), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 195/362 (54%), Positives = 240/362 (67%), Gaps = 17/362 (4%) Query 11 GTASLAAGTW-LLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREE 69 GTA+LA + RAL G P D ++ + SP Y+ G+F N P + L R Sbjct 10 GTATLAVAVKDVYRALGGRP-----DPHTLWS----SPQYQGGSFHN--PRPVRWLPRGS 58 Query 70 LRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPV 129 +R + E+V +P +PL P + L V+WFGH+++L+E+DG RVL DP+ Sbjct 59 VRNAMREMVRAGRPRKPRGTVPLVGPAPAPTEG--LHVTWFGHASSLVELDGARVLIDPM 116 Query 130 WSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLV 189 WS R SPS VGP+RLHP P +L LP +DA+VISHDHYDHLD+ TV LV +Q APF+V Sbjct 117 WSKRASPSQWVGPRRLHPVPHRLVDLPRLDAIVISHDHYDHLDMATVRELVRIQPAPFVV 176 Query 190 PLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFV 249 PLGVGAHLR+WGVP+ RIVELDW + AQV L + PA+HFSGR +RNTTLWASW Sbjct 177 PLGVGAHLRAWGVPKARIVELDWYEQAQVSSLRITATPAQHFSGRAFTRNTTLWASWVLE 236 Query 250 GPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT 309 R ++ GDTGY +F IG D+GPFDLTL+ IGAY T+WPDIHM PEE V HLDV Sbjct 237 RKRRRVFYSGDTGYCDAFADIGRDYGPFDLTLIQIGAYATSWPDIHMTPEEGVATHLDVR 296 Query 310 DSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPW 369 G+ VPVHWGTF LAPH W EPVER+L AA + V VAVP PGQR+D + P L PW Sbjct 297 ---GGLFVPVHWGTFVLAPHGWAEPVERVLRAAGEQGVRVAVPRPGQRIDVSAPPELVPW 353 Query 370 WR 371 WR Sbjct 354 WR 355 >gi|289568873|ref|ZP_06449100.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] gi|289542627|gb|EFD46275.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] Length=182 Score = 356 bits (914), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 182/182 (100%), Positives = 182/182 (100%), Gaps = 0/182 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA Sbjct 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID Sbjct 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV Sbjct 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 Query 181 GM 182 GM Sbjct 181 GM 182 >gi|289752961|ref|ZP_06512339.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] gi|289693548|gb|EFD60977.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] Length=182 Score = 353 bits (907), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 181/182 (99%), Positives = 181/182 (99%), Gaps = 0/182 (0%) Query 1 MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 MVRRALRLAAGTASLAAGT LLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA Sbjct 1 MVRRALRLAAGTASLAAGTSLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA 60 Query 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID Sbjct 61 SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID 120 Query 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV Sbjct 121 GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV 180 Query 181 GM 182 GM Sbjct 181 GM 182 >gi|296269651|ref|YP_003652283.1| beta-lactamase domain-containing protein [Thermobispora bispora DSM 43833] gi|296092438|gb|ADG88390.1| beta-lactamase domain protein [Thermobispora bispora DSM 43833] Length=367 Score = 352 bits (904), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 189/367 (52%), Positives = 236/367 (65%), Gaps = 11/367 (2%) Query 5 ALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFT 64 ALRL +LA WL R + PA A +S + G F N P S Sbjct 9 ALRLLGVLFALAGAGWLARDI--VPALGARPAGERARRIRRSERFGGGRFRNPVPTS--G 64 Query 65 LDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRV 124 R R ++ EL R RP P+PL +P+ G AS L V W+GH++ L+EI+G RV Sbjct 65 RRRGTARAVLGEL--RSGPRRPRGPVPLVTPSP--GPASDLDVVWYGHASVLIEIEGRRV 120 Query 125 LTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQR 184 L DPVWS+RCSPS + GP+RLHP PV LA LP +DA+VISHDHYDHLD+ TV L +QR Sbjct 121 LFDPVWSERCSPSPIAGPRRLHPAPVPLAGLPELDAIVISHDHYDHLDMATVRELTRLQR 180 Query 185 APFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWA 244 APF VPLGVGAHL WGVP RI+ELDW++ ++ L + ARHFSGRF++RN TLWA Sbjct 181 APFAVPLGVGAHLERWGVPASRIIELDWDEETKLSGLRLTATAARHFSGRFIARNPTLWA 240 Query 245 SWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRA 304 SW G R ++ GD+GY + IG +GPFDL+++ IGAY+ AWPD+HM PEEAVRA Sbjct 241 SWVVAGERRRVFYTGDSGYFDGYAAIGRAYGPFDLSVIQIGAYSAAWPDVHMTPEEAVRA 300 Query 305 HLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPM 364 HLD+ +G+L+PVHWGTFRLAPH W +PVERL A V +AVP PG+RV P Sbjct 301 HLDLR---AGLLLPVHWGTFRLAPHSWSDPVERLCREARAHGVRLAVPRPGERVSADDPP 357 Query 365 RLHPWWR 371 + WWR Sbjct 358 PVDGWWR 364 >gi|271965366|ref|YP_003339562.1| hypothetical protein Sros_3902 [Streptosporangium roseum DSM 43021] gi|270508541|gb|ACZ86819.1| conserved hypothetical protein [Streptosporangium roseum DSM 43021] Length=371 Score = 350 bits (899), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 188/345 (55%), Positives = 225/345 (66%), Gaps = 5/345 (1%) Query 29 PAALGADAASIR-AVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPA 87 PA LG A R A +SP + DG F N P S +T + ++ EL+ +P Sbjct 28 PAELGGRATGERLARMLRSPRFHDGVFHNPVPGS-YTPPVSSVPAMLRELIFDRDGRKPG 86 Query 88 APIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHP 147 PIPL + A L+V W+GH+T L+EI+G RVL DPVWS+R SPS +VGP+RLHP Sbjct 87 GPIPLVTSPATPPSAGGLSVVWYGHATTLVEIEGRRVLFDPVWSERASPSRLVGPRRLHP 146 Query 148 PPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRI 207 P LA LP +DA+VISHDHYDHLD TV AL +Q APFLVPLG+GAHL WGVP RI Sbjct 147 LPAPLADLPVLDAIVISHDHYDHLDRATVRALTALQSAPFLVPLGIGAHLERWGVPASRI 206 Query 208 VELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSF 267 VELDW + A V L V ARHFSGR L+RNTTLW SW G R ++ GD+GY + Sbjct 207 VELDWEEEATVAGLRFVATAARHFSGRALTRNTTLWGSWVVAGRTRRVFYAGDSGYFDGY 266 Query 268 TQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLA 327 IGA HGPFDLTL+PIGAY+ AWPDIHM+PEEA+ AHLD+ G +L+PVHW TF LA Sbjct 267 AGIGAAHGPFDLTLMPIGAYSPAWPDIHMDPEEAIDAHLDL---GGRLLLPVHWATFTLA 323 Query 328 PHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL 372 HPW EPV+RL A+ V +AVP PG RVD L WW L Sbjct 324 VHPWAEPVDRLRHEAKARGVRLAVPRPGDRVDTDDVPLLDGWWEL 368 >gi|315503022|ref|YP_004081909.1| zn-dependent hydrolase [Micromonospora sp. L5] gi|315409641|gb|ADU07758.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Micromonospora sp. L5] Length=381 Score = 350 bits (898), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 185/347 (54%), Positives = 234/347 (68%), Gaps = 7/347 (2%) Query 28 TPAALGADAASIRAV-SEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRP 86 PA LG RA + +SP +RDG F N AS T+ + R ++ ELV RP Sbjct 36 VPAQLGGRLTGARAERAARSPRFRDGTFHNPAGASA-TMVADPGRNLLRELVFGKQKRRP 94 Query 87 AAPIPLASPNIY--RGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQR 144 +P+PL P A L V W+GH++ L+EI+G+RVL DPVWSDRCSPS +VGP+R Sbjct 95 GSPVPLLHPGAAPAADQARELNVVWYGHASTLVEIEGHRVLLDPVWSDRCSPSGLVGPRR 154 Query 145 LHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQ 204 +H PPV+L LP +DAV+ISHDHYDHLD++TV L +Q APF+VPLGVGAHL WGVP+ Sbjct 155 IHEPPVRLTDLPPLDAVLISHDHYDHLDMETVRTLADLQSAPFVVPLGVGAHLARWGVPE 214 Query 205 DRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYT 264 RIVELDW++S + LT+ A+HFSGR L R+ TLW+SW G + + ++ GD+GY Sbjct 215 HRIVELDWSESHRAGGLTLTATAAQHFSGRGLRRDGTLWSSWTITGAHRKVFYTGDSGYF 274 Query 265 KSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTF 324 + IGADHGPFD+TL+ IGAY+ AWP IHM PEEAV AHLDV G+LVPVHWGTF Sbjct 275 DGYAAIGADHGPFDVTLMQIGAYDRAWPHIHMFPEEAVAAHLDVR---GGLLVPVHWGTF 331 Query 325 RLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 LA H W EPV+RL A A+ V +AVP PG+RV P + WW+ Sbjct 332 NLALHDWSEPVDRLWAEAKARDVRLAVPRPGERVVVDEPPAVDGWWQ 378 >gi|302866614|ref|YP_003835251.1| Zn-dependent hydrolase [Micromonospora aurantiaca ATCC 27029] gi|302569473|gb|ADL45675.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Micromonospora aurantiaca ATCC 27029] Length=381 Score = 349 bits (895), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 185/347 (54%), Positives = 237/347 (69%), Gaps = 7/347 (2%) Query 28 TPAALGADAASIRAV-SEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRP 86 PA LG RA + +SP +RDG F N AS T+ + R ++ ELV RP Sbjct 36 VPAQLGGRLTGARAERAARSPRFRDGTFHNPAGASA-TMVADPGRNLLRELVFGKQKRRP 94 Query 87 AAPIPLASPNIY-RGDASR-LAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQR 144 +P+PL P GD +R L V W+GH++ L+EI+G+RVL DPVWSDRCSPS +VGP+R Sbjct 95 GSPVPLLHPGAAPAGDQARELNVVWYGHASTLVEIEGHRVLLDPVWSDRCSPSGLVGPRR 154 Query 145 LHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQ 204 +H PPV+L LP +DAV+ISHDHYDHLD++TV L +Q APF+VPLGVGAHL WG+P+ Sbjct 155 IHEPPVRLTDLPPLDAVLISHDHYDHLDMETVRTLADLQSAPFVVPLGVGAHLARWGLPE 214 Query 205 DRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYT 264 RIVELDW++S + LT+ A+HFSGR L R+ TLW+SW G + + ++ GD+GY Sbjct 215 HRIVELDWSESHRAGGLTLTATAAQHFSGRGLRRDGTLWSSWTITGAHRKVFYTGDSGYF 274 Query 265 KSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTF 324 + IGA+HGPFD+TL+ IGAY+ AWP IHM PEEAV AHLDV G+LVPVHWGTF Sbjct 275 DGYAAIGAEHGPFDVTLMQIGAYDRAWPHIHMFPEEAVAAHLDVR---GGLLVPVHWGTF 331 Query 325 RLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 LA H W EPV+RL A A+ V +AVP PG+RV P + WW+ Sbjct 332 NLALHDWSEPVDRLWAEAKARDVRLAVPRPGERVVVDEPPAVDGWWQ 378 >gi|296141042|ref|YP_003648285.1| hypothetical protein Tpau_3362 [Tsukamurella paurometabola DSM 20162] gi|296029176|gb|ADG79946.1| conserved hypothetical protein [Tsukamurella paurometabola DSM 20162] Length=396 Score = 344 bits (883), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 190/359 (53%), Positives = 234/359 (66%), Gaps = 32/359 (8%) Query 16 AAGTWLLRALHGTPAALGADAASIRAVSE-QSPNYRDGAFVNLDPASMFTLDREELRLIV 74 A G +LLRA G ++GA A ++ S+ SP+ R +P + LR ++ Sbjct 22 ATGVYLLRAGRGLRRSMGAQADTVYTNSDPDSPHER------FEPGKI-------LRGVL 68 Query 75 WELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRC 134 ARH RP+ PIPL +P + DA+ LAV+W+GHS+ L+EIDG+RVL DPVW +R Sbjct 69 GR--ARHGQGRPSRPIPLVAP-LSPVDAADLAVTWYGHSSVLIEIDGFRVLADPVWGERV 125 Query 135 SPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVG 194 SPS +GP RLHP PV L+ALP +DAV+ISHDHYDHLD+ T+ L + PF VP+GVG Sbjct 126 SPSPTIGPSRLHPVPVALSALPPIDAVIISHDHYDHLDLPTIDELTRDRDVPFCVPIGVG 185 Query 195 AHLRSWGVPQDRIVELDWNQSAQV---------DELTVVCVPARHFSGRFLSRNTTLWAS 245 HLR+WGVP+DRI+ELDW+QS + DEL VVC ARHFSGR L+RN+T WAS Sbjct 186 GHLRAWGVPEDRIIELDWDQSHTLTRDDGHDGTDELKVVCTEARHFSGRGLTRNSTQWAS 245 Query 246 WAFV-----GPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE 300 W+ V G H +FGGDTGYT+ F IG GPFDLTLLPIGAY+ WPD+H NPEE Sbjct 246 WSLVGRKASGQGHSVFFGGDTGYTERFKLIGDHFGPFDLTLLPIGAYDPLWPDVHTNPEE 305 Query 301 AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVD 359 AV H + LVPVHW TF LA H W EPVERLL AA+ +T VP PG RVD Sbjct 306 AVAIHQMIAGP-KAPLVPVHWATFNLAFHDWSEPVERLLVAAKDAGITTVVPKPGGRVD 363 >gi|330466773|ref|YP_004404516.1| zn-dependent hydrolase of the beta-lactamase fold-like protein [Verrucosispora maris AB-18-032] gi|328809744|gb|AEB43916.1| zn-dependent hydrolase of the beta-lactamase fold-like protein [Verrucosispora maris AB-18-032] Length=379 Score = 343 bits (879), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 187/349 (54%), Positives = 227/349 (66%), Gaps = 12/349 (3%) Query 28 TPAALGADAASIRAVSEQ-SPNYRDGAFVNL--DPASMFTLDREELRLIVWELVARHSAS 84 PAALG A RA SP +RDG F N P + DR LR EL+ Sbjct 35 VPAALGGRLAGARADRAARSPQFRDGVFHNRPGTPITAPAPDRNLLR----ELLFGKQKR 90 Query 85 RPAAPIPLASPNIYR--GDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGP 142 RP+AP+PL P A L V W+GH+T L+EI+G RVL DPVWS+RCSPS +GP Sbjct 91 RPSAPVPLVRPVAATPVDPARELNVIWYGHATTLVEIEGRRVLLDPVWSERCSPSATLGP 150 Query 143 QRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGV 202 +RLH PPV+L LP +DA++ISHDHYDHLD+ TV L Q APFLVPLGVGAHL WGV Sbjct 151 RRLHEPPVRLDELPHLDAILISHDHYDHLDMATVRELTARQSAPFLVPLGVGAHLDRWGV 210 Query 203 PQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTG 262 P DRI+ELDW Q+ +V EL + C A+HFSGR L RN TLW+SW G R Y+ GD+G Sbjct 211 PADRIIELDWTQTHRVAELEITCAAAQHFSGRGLRRNGTLWSSWVVAGRQRRVYYTGDSG 270 Query 263 YTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWG 322 Y + +IGA +GPFD+TL+ IGAY+ AW IHM PEEAV AH+D+ G+LVPVHW Sbjct 271 YFAGYAEIGAAYGPFDVTLIQIGAYDHAWASIHMFPEEAVAAHVDLR---GGLLVPVHWA 327 Query 323 TFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 TF LA H W EPV+RL A A+ V +AVP PG+RV P + WW+ Sbjct 328 TFNLALHDWSEPVDRLWAEAKARDVRLAVPRPGERVTVDDPPSVDGWWQ 376 >gi|256379964|ref|YP_003103624.1| hypothetical protein Amir_5970 [Actinosynnema mirum DSM 43827] gi|255924267|gb|ACU39778.1| conserved hypothetical protein [Actinosynnema mirum DSM 43827] Length=360 Score = 342 bits (877), Expect = 6e-92, Method: Compositional matrix adjust. Identities = 176/329 (54%), Positives = 220/329 (67%), Gaps = 9/329 (2%) Query 45 QSPNYRDGAFVNLDPASMFTLD--REELRLIVWELVARHSASRPAAPIPLASPNIYRGDA 102 +SP +RDG F N S D E LR + + +PA P+PL +P A Sbjct 37 RSPQWRDGKFHNRATTSTMPPDGATETLRDFAF---GDKTKRKPAGPVPLVAPR-RDAPA 92 Query 103 SRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVV 162 L ++W+GH+++L+EIDG RVL DP+WSDRCSPS VVGP+RLH P +L L VDAVV Sbjct 93 DGLHITWYGHASSLVEIDGARVLIDPIWSDRCSPSQVVGPRRLHAVPHELDELGRVDAVV 152 Query 163 ISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELT 222 ISHDHYDHLD+ TV AL A F+VPLG+GAHLRSW VP+ RIVELDWN+S +V +T Sbjct 153 ISHDHYDHLDLPTVRALTRDHAAVFVVPLGIGAHLRSWDVPEHRIVELDWNESHRVAGIT 212 Query 223 VVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLL 282 + PA+HFSGR L+R+TTLWASW GP HR Y+ GDTGY + +IG +HGPFD L+ Sbjct 213 LTATPAQHFSGRGLARDTTLWASWVIAGPEHRVYYTGDTGYFDGYAEIGEEHGPFDAALV 272 Query 283 PIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAA 342 IGAY + WPDIHM PEE V AH DV G+L+PVHW TF LA H W EPV+R+ A Sbjct 273 QIGAYGSGWPDIHMTPEEGVAAHRDVR---GGLLIPVHWATFNLALHDWSEPVDRVWREA 329 Query 343 EPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 + V +AVP PG+R+D P + WW+ Sbjct 330 KAHDVRMAVPKPGERIDVANPPAVDGWWQ 358 >gi|145594252|ref|YP_001158549.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Salinispora tropica CNB-440] gi|145303589|gb|ABP54171.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Salinispora tropica CNB-440] Length=386 Score = 337 bits (863), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 188/375 (51%), Positives = 238/375 (64%), Gaps = 24/375 (6%) Query 9 AAGTASLAAGTWLLRALHGTPAALGADAASIRAVSE-QSPNYRDGAFVNLDPAS------ 61 A G A+LA W +R + P ALG A RA SP YR GAF N PAS Sbjct 21 AVGMAALAGLGWAVRDV---PLALGGRLAGARAERALSSPQYRAGAFRN--PASSRPAAS 75 Query 62 --MFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASR---LAVSWFGHSTAL 116 + DR LR + RH P+ P+PL P ++R L V W+GH++ L Sbjct 76 PTTGSTDRNLLREFFFGKQKRH----PSLPVPLVRPAHAPESSTRSRELNVVWYGHASTL 131 Query 117 LEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTV 176 +EI+ +RVL DPVWS RCSPS+++GP+RLH PP+ LA LP VDA++ISHDHYDHLD++TV Sbjct 132 VEIETHRVLIDPVWSQRCSPSNLIGPKRLHEPPIGLAELPTVDAILISHDHYDHLDLETV 191 Query 177 VALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFL 236 L Q APF+VPLGVGAHL WGVP+ RIVELDW++S +V L + PA+HFSGR L Sbjct 192 RELTARQDAPFVVPLGVGAHLERWGVPERRIVELDWSESHEVAGLRLTATPAQHFSGRGL 251 Query 237 SRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHM 296 R+ TLW+SW G + ++ GD+GY + IGA +GPFD+TL+ IGAY+ AW DIHM Sbjct 252 RRDATLWSSWVIAGAHRSVFYTGDSGYFDGYAAIGAGYGPFDVTLMQIGAYDWAWRDIHM 311 Query 297 NPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQ 356 PEEAV AHLD+ G+L+PVHW TF LA H W EPV+RL A + V + VP PGQ Sbjct 312 FPEEAVAAHLDLR---GGLLLPVHWATFNLAVHDWSEPVDRLWAETKARDVRLTVPRPGQ 368 Query 357 RVDPTGPMRLHPWWR 371 RV P + WW+ Sbjct 369 RVVVDDPPPVDGWWQ 383 >gi|345010512|ref|YP_004812866.1| hypothetical protein Strvi_2887 [Streptomyces violaceusniger Tu 4113] gi|344036861|gb|AEM82586.1| hypothetical protein Strvi_2887 [Streptomyces violaceusniger Tu 4113] Length=419 Score = 336 bits (862), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 188/360 (53%), Positives = 223/360 (62%), Gaps = 28/360 (7%) Query 29 PAALGADAASIRAVS-EQSPNYRDGAFVN------------LDPASMFTLDREELRLIVW 75 PAA GAD A R +SPN+ +G FVN L AS + E +R Sbjct 17 PAAFGADPAGERMERIRRSPNFANGVFVNPVGARIGPSGSMLKFASTYFRKEERVRRAPA 76 Query 76 ELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCS 135 V H P ++ AS L ++W GHS+ L EIDG RVL DPVW RCS Sbjct 77 GTVPVH---------PTTVADLATRPASGLRLTWMGHSSVLAEIDGRRVLFDPVWGQRCS 127 Query 136 PSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGA 195 P +VGP+RLHP PV L L VDAVVISHDHYDHLD+ T+ ALV A F+VPLGVGA Sbjct 128 PFAMVGPKRLHPVPVPLRELAPVDAVVISHDHYDHLDMPTIRALV-RGHAMFVVPLGVGA 186 Query 196 HLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT--TLWASWAFVGPNH 253 HL WGVP DR+ ELDW++S +V LT+ PARHF GR L RNT TLWASW GP H Sbjct 187 HLERWGVPADRMTELDWHESTEVAGLTLTATPARHFCGRGL-RNTQHTLWASWVVAGPEH 245 Query 254 RAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DS 311 R Y GDTGY F +IGA +GPFD T++ IGAY+ WPDIHM PEE +RAHLD+ D Sbjct 246 RVYHSGDTGYFPGFKEIGAAYGPFDATMVQIGAYSDYWPDIHMTPEEGMRAHLDLQGGDP 305 Query 312 GSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 G+++P+HWGTF LAPHPW EP E ++AAE VAVP PGQ +P + L PWWR Sbjct 306 AKGIMLPIHWGTFNLAPHPWEEPAEGTVSAAEEAGANVAVPRPGQPFEPGQGLPLEPWWR 365 >gi|159037329|ref|YP_001536582.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Salinispora arenicola CNS-205] gi|157916164|gb|ABV97591.1| Zn-dependent hydrolase of the beta-lactamase fold-like protein [Salinispora arenicola CNS-205] Length=385 Score = 332 bits (852), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 182/360 (51%), Positives = 230/360 (64%), Gaps = 21/360 (5%) Query 24 ALHGTPAALGADAASIRAVSE-QSPNYRDGAFVNLDPAS--------MFTLDREELRLIV 74 ++ P ALG RA +SP YR GAF N PAS + DR LR + Sbjct 32 SVRDVPLALGGRLTGARAERALRSPQYRAGAFRN--PASSRPAASPTTGSTDRNLLRELF 89 Query 75 WELVARHSASRPAAPIPLASPNIYRGDASR---LAVSWFGHSTALLEIDGYRVLTDPVWS 131 + RH P+ P+PL P ++R L V W+GH++AL+EI+G VL DPVWS Sbjct 90 FGKQKRH----PSLPVPLVRPTRPPQTSARSRELNVIWYGHASALVEIEGRTVLIDPVWS 145 Query 132 DRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPL 191 RCSPS +GP+RLH PPV L LPAVDA++ISHDHYDHLD+ TV L Q APF+VPL Sbjct 146 QRCSPSARLGPKRLHAPPVGLDELPAVDAILISHDHYDHLDLATVRGLTARQEAPFVVPL 205 Query 192 GVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGP 251 GVGAHL WGVP+ RIVELDW++S V L + PA+HFSGR L R+TTLW+SW G Sbjct 206 GVGAHLERWGVPEHRIVELDWSESHDVAGLRLTATPAQHFSGRGLRRDTTLWSSWVIAGA 265 Query 252 NHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDS 311 + ++ GD+GY + IGA +GPFD+TL+ IGAY+ AW DIHM PE+AV AHLD+ Sbjct 266 HRSVFYTGDSGYFDGYAAIGAGYGPFDVTLMQIGAYDQAWQDIHMFPEDAVSAHLDLR-- 323 Query 312 GSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 G+L+PVHW TF LA H W EPV+RL A A+ V + VP PG+RV P+ + WW+ Sbjct 324 -GGLLLPVHWATFNLAVHDWSEPVDRLWAEAKARDVRLVVPRPGERVVVNDPIPVDGWWQ 382 >gi|300784434|ref|YP_003764725.1| Zn-dependent hydrolase of the beta-lactamase fold family [Amycolatopsis mediterranei U32] gi|299793948|gb|ADJ44323.1| Zn-dependent hydrolase of the beta-lactamase fold family [Amycolatopsis mediterranei U32] gi|340525855|gb|AEK41060.1| Zn-dependent hydrolase of the beta-lactamase fold family protein [Amycolatopsis mediterranei S699] Length=353 Score = 332 bits (851), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 180/357 (51%), Positives = 226/357 (64%), Gaps = 17/357 (4%) Query 22 LRALHGTPAALGADAASIRAVS-EQSPNYRDGAFVNLDP------ASMFTLDREELRLIV 74 + AL PAA GA A RA SP + F N P ASM T+ RE Sbjct 5 IAALRDLPAAFGAKATGARAERVRSSPQFDGKVFRNAAPRHPMTAASMRTIFREMFFGEH 64 Query 75 WELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRC 134 EL +PA +PL + A L ++W+GH++ L+E+DG RVL DPVWSDR Sbjct 65 REL------RKPAGAVPLVAAAPVE-SADGLHLTWYGHASTLVELDGARVLLDPVWSDRV 117 Query 135 SPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVG 194 SP+ GP+RLH PPV L+AL +DAVVISHDHYDHLD+ TV ALV APFLVPLGVG Sbjct 118 SPAAFAGPRRLHEPPVPLSALGRIDAVVISHDHYDHLDLATVRALVTSSEAPFLVPLGVG 177 Query 195 AHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHR 254 AHL W VP +RI+ELDW++ A V + V PA+HFSGR ++ + TLW SWA +GP HR Sbjct 178 AHLERWHVPAERIIELDWHEEATVAGVRFVATPAQHFSGRGITNDDTLWTSWALLGPEHR 237 Query 255 AYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSG 314 ++ GDTGY F IGA+HGPFD L+ IGAY WPDIHM PEE V A LDV + Sbjct 238 VFYSGDTGYFDGFAAIGAEHGPFDAALIQIGAYAPLWPDIHMTPEEGVAAGLDVR---AK 294 Query 315 MLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 +LVPVHW TF+LA HPWGEP +R+ + A+ + +A+P PG+R+D P + WW+ Sbjct 295 LLVPVHWATFQLAMHPWGEPADRVWSEAKEADLPLAIPRPGERIDAAEPPAVDGWWQ 351 >gi|302525672|ref|ZP_07278014.1| metallo-beta-lactamase [Streptomyces sp. AA4] gi|302434567|gb|EFL06383.1| metallo-beta-lactamase [Streptomyces sp. AA4] Length=349 Score = 325 bits (832), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 173/334 (52%), Positives = 214/334 (65%), Gaps = 17/334 (5%) Query 44 EQSPNYRDGAFVNL-----DPASMFTLDREELRLIVWELVARHSASRPAAPIPLAS-PNI 97 QSP Y DG F N PAS L RE + E AR RP +PL S P Sbjct 24 RQSPQYADGVFHNAAATRATPASPGALVRE---FLFGEDRARR---RPGGAVPLVSAPAA 77 Query 98 YRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPA 157 D L ++W+GH++ L+EIDG RVL DPVW +R SP+ GP+RLH PPV L L Sbjct 78 TAADG--LFLTWYGHASTLVEIDGARVLCDPVWGERVSPTTFAGPRRLHAPPVSLRELGR 135 Query 158 VDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQ 217 +DA+VISHDHYDHLD+ TV AL+ + APFLVPLGVGAHL W VP RI+ELDW++ A Sbjct 136 LDAIVISHDHYDHLDLPTVQALIALTDAPFLVPLGVGAHLERWHVPAARIIELDWHEDAV 195 Query 218 VDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPF 277 V + V PA+HFSGR L+ ++TLWASW GP HR Y+ GDTGY F +IGA +GPF Sbjct 196 VAGIRFVATPAQHFSGRGLANDSTLWASWVLAGPEHRVYYSGDTGYFAGFAEIGAKYGPF 255 Query 278 DLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVER 337 D TL+ +GAY WPDIHM PEE V AHLDV G+LVPVHW TF LA H W +P +R Sbjct 256 DATLIQVGAYAPNWPDIHMTPEEGVAAHLDVR---GGLLVPVHWATFTLAMHTWSDPADR 312 Query 338 LLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 + A+ + +A+P PGQR+D + P + WW+ Sbjct 313 VWREAKANDLPLAIPKPGQRIDASAPPPVDGWWQ 346 >gi|329937118|ref|ZP_08286747.1| metallo-beta-lactamase [Streptomyces griseoaurantiacus M045] gi|329303725|gb|EGG47610.1| metallo-beta-lactamase [Streptomyces griseoaurantiacus M045] Length=393 Score = 324 bits (831), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 183/369 (50%), Positives = 220/369 (60%), Gaps = 14/369 (3%) Query 11 GTASLAAGTWLLRALHGTPAALGADAASIR-AVSEQSPNYRDGAFVNLDPASMFTLDREE 69 G SL +G LR P + GAD R A +SPN+ DG FVN D Sbjct 3 GLPSLGSGRSPLR-----PLSFGADPTGERLARIRRSPNFADGVFVNPDGPRTRESGGSA 57 Query 70 LRLIVWELVARHSASR-PAAPIPL---ASPNIYRGDASRLAVSWFGHSTALLEIDGYRVL 125 L + A R P IP+ ++ R S L ++W GHS+ L EIDG RVL Sbjct 58 LGIAKQYFEKGSRARRAPTGTIPVHPTTVADLARPPKSGLRITWVGHSSVLAEIDGRRVL 117 Query 126 TDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRA 185 DPVW RCSP D VGP+RLHP P+ AAL VD VVISHDHYDHLD+ T+ L G Sbjct 118 FDPVWGQRCSPFDFVGPKRLHPVPLPQAALGPVDVVVISHDHYDHLDLPTIKKLAGTDTL 177 Query 186 PFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFL-SRNTTLWA 244 F VPLGVGAHL WGV DR+ ELDWN+S +V LT+ PARHF GR + +R TLWA Sbjct 178 -FAVPLGVGAHLERWGVSPDRLRELDWNESTRVGGLTLTATPARHFCGRGIRNRQHTLWA 236 Query 245 SWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRA 304 SW G NHR Y GDTGY F IGA+HGPFD T++ IGAY+ WPDIHM PEE V A Sbjct 237 SWVVAGENHRIYHSGDTGYFHGFKDIGAEHGPFDATMIQIGAYSDMWPDIHMTPEEGVDA 296 Query 305 HLDVT--DSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTG 362 H+D+ D+ +G+L+P+HWGTF LAPHPW EP ER + AA + P PG+ +P Sbjct 297 HVDLQKGDAAAGVLLPIHWGTFNLAPHPWAEPGERTMWAARRAGARMVAPRPGEPFEPAA 356 Query 363 PMRLHPWWR 371 + PWWR Sbjct 357 VGAVVPWWR 365 >gi|302541316|ref|ZP_07293658.1| metallo-beta-lactamase [Streptomyces hygroscopicus ATCC 53653] gi|302458934|gb|EFL22027.1| metallo-beta-lactamase [Streptomyces himastatinicus ATCC 53653] Length=404 Score = 324 bits (830), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 188/359 (53%), Positives = 222/359 (62%), Gaps = 26/359 (7%) Query 29 PAALGADAASIRAVS-EQSPNYRDGAFVN------LDPASMF----TLDREELRLIVWEL 77 PAA GAD A R +SPN+ +G F N SM T R+E R Sbjct 17 PAAFGADPAGERMERIRRSPNFANGVFTNPGGGRSAPSGSMLKFLPTYFRKENR------ 70 Query 78 VARHSASR-PAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSP 136 V R A P P LA ++ AS L ++W GHS+ L EIDG RVL DPVW RCSP Sbjct 71 VRRAPAGTVPVHPTTLA--DLATPPASGLRLTWMGHSSVLAEIDGRRVLFDPVWGSRCSP 128 Query 137 SDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAH 196 VGP+RLHP PV L L VDAVVISHDHYDHLD+ T+ ALV F+VPLGVGAH Sbjct 129 FASVGPKRLHPVPVPLRELGPVDAVVISHDHYDHLDMPTIRALVRTGTM-FVVPLGVGAH 187 Query 197 LRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT--TLWASWAFVGPNHR 254 L WGVP DR+ ELDW++S V L + PARHF GR L RNT TLWASW GP HR Sbjct 188 LEHWGVPADRVTELDWHESTDVAGLLLTATPARHFCGRAL-RNTQHTLWASWVVAGPEHR 246 Query 255 AYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVT--DSG 312 + GDTGY F +IGA +GPFD T++ IGAY+ WPDIHM PEE +RAHLD+ + G Sbjct 247 IFHSGDTGYFSGFAEIGASYGPFDATMIQIGAYSEFWPDIHMTPEEGMRAHLDLQGGEPG 306 Query 313 SGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWR 371 G+++P+HWGTF LAPHPW EP E + AA +VAVP PGQ +P + L PWWR Sbjct 307 RGIMLPIHWGTFNLAPHPWEEPAEGTVTAARAVGASVAVPRPGQPFEPVRGLPLEPWWR 365 Lambda K H 0.321 0.136 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 709746472050 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40