BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0907 Length=532 Score E Sequences producing significant alignments: (Bits) Value gi|15608047|ref|NP_215422.1| hypothetical protein Rv0907 [Mycoba... 1083 0.0 gi|254363837|ref|ZP_04979883.1| conserved hypothetical protein [... 1039 0.0 gi|15840326|ref|NP_335363.1| penicillin-binding protein 4 [Mycob... 1038 0.0 gi|167967694|ref|ZP_02549971.1| hypothetical protein MtubH3_0650... 1038 0.0 gi|308374130|ref|ZP_07434983.2| hypothetical protein TMFG_02717 ... 1038 0.0 gi|297633426|ref|ZP_06951206.1| hypothetical protein MtubK4_0485... 1038 0.0 gi|289442318|ref|ZP_06432062.1| penicillin-binding protein 4 [My... 1037 0.0 gi|289749430|ref|ZP_06508808.1| conserved hypothetical protein [... 1036 0.0 gi|289756993|ref|ZP_06516371.1| penicillin-binding protein 4 [My... 1036 0.0 gi|339293917|gb|AEJ46028.1| penicillin-binding protein 4 [Mycoba... 1036 0.0 gi|294996388|ref|ZP_06802079.1| hypothetical protein Mtub2_18274... 1036 0.0 gi|121636830|ref|YP_977053.1| hypothetical protein BCG_0959 [Myc... 1035 0.0 gi|298524399|ref|ZP_07011808.1| penicillin-binding protein 4 [My... 1035 0.0 gi|31792095|ref|NP_854588.1| hypothetical protein Mb0931 [Mycoba... 1034 0.0 gi|340625918|ref|YP_004744370.1| hypothetical protein MCAN_09071... 1004 0.0 gi|339297557|gb|AEJ49667.1| penicillin-binding protein 4 [Mycoba... 957 0.0 gi|289568874|ref|ZP_06449101.1| conserved hypothetical protein [... 899 0.0 gi|240172194|ref|ZP_04750853.1| penicillin binding protein [Myco... 811 0.0 gi|183984590|ref|YP_001852881.1| penicillin binding protein [Myc... 806 0.0 gi|342860513|ref|ZP_08717164.1| hypothetical protein MCOL_16601 ... 774 0.0 gi|296169665|ref|ZP_06851283.1| beta-lactamase [Mycobacterium pa... 763 0.0 gi|254822960|ref|ZP_05227961.1| penicillin-binding protein 4 [My... 756 0.0 gi|118463767|ref|YP_880286.1| penicillin-binding protein 4 [Myco... 736 0.0 gi|41406940|ref|NP_959776.1| hypothetical protein MAP0842 [Mycob... 733 0.0 gi|118470511|ref|YP_889871.1| penicillin-binding protein 4 [Myco... 617 2e-174 gi|145222347|ref|YP_001133025.1| beta-lactamase [Mycobacterium g... 614 1e-173 gi|120405939|ref|YP_955768.1| beta-lactamase [Mycobacterium vanb... 612 7e-173 gi|111022825|ref|YP_705797.1| hypothetical protein RHA1_ro05862 ... 606 3e-171 gi|226365333|ref|YP_002783116.1| penicillin-binding protein [Rho... 598 5e-169 gi|126437375|ref|YP_001073066.1| beta-lactamase [Mycobacterium s... 597 1e-168 gi|108801392|ref|YP_641589.1| beta-lactamase [Mycobacterium sp. ... 596 3e-168 gi|262200737|ref|YP_003271945.1| beta-lactamase [Gordonia bronch... 582 5e-164 gi|343925723|ref|ZP_08765238.1| putative penicillin-binding prot... 562 4e-158 gi|229493944|ref|ZP_04387716.1| penicillin-binding protein 4 [Rh... 559 5e-157 gi|154245570|ref|YP_001416528.1| beta-lactamase [Xanthobacter au... 547 2e-153 gi|54024183|ref|YP_118425.1| hypothetical protein nfa22140 [Noca... 546 4e-153 gi|226307733|ref|YP_002767693.1| penicillin-binding protein [Rho... 545 7e-153 gi|194289848|ref|YP_002005755.1| beta-lactamase [Cupriavidus tai... 530 3e-148 gi|113868104|ref|YP_726593.1| Beta-lactamase class C [Ralstonia ... 523 3e-146 gi|339326183|ref|YP_004685876.1| beta-lactamase class C [Cupriav... 521 1e-145 gi|75674850|ref|YP_317271.1| beta-lactamase [Nitrobacter winogra... 507 2e-141 gi|220924478|ref|YP_002499780.1| beta-lactamase [Methylobacteriu... 504 2e-140 gi|258654767|ref|YP_003203923.1| beta-lactamase [Nakamurella mul... 491 1e-136 gi|338996917|ref|ZP_08635623.1| beta-lactamase [Halomonas sp. TD... 478 2e-132 gi|239820768|ref|YP_002947953.1| beta-lactamase [Variovorax para... 470 3e-130 gi|118591784|ref|ZP_01549180.1| beta-lactamase [Stappia aggregat... 469 4e-130 gi|328883567|emb|CCA56806.1| Beta-lactamase [Streptomyces venezu... 455 9e-126 gi|344341418|ref|ZP_08772338.1| beta-lactamase [Thiocapsa marina... 454 2e-125 gi|333917323|ref|YP_004491055.1| beta-lactamase [Delftia sp. Cs1... 446 7e-123 gi|160896254|ref|YP_001561836.1| beta-lactamase [Delftia acidovo... 445 1e-122 >gi|15608047|ref|NP_215422.1| hypothetical protein Rv0907 [Mycobacterium tuberculosis H37Rv] gi|3261758|emb|CAB08514.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv] Length=532 Score = 1083 bits (2802), Expect = 0.0, Method: Compositional matrix adjust. Identities = 531/532 (99%), Positives = 532/532 (100%), Gaps = 0/532 (0%) Query 1 LATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAV 60 +ATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAV Sbjct 1 MATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAV 60 Query 61 AKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLAS 120 AKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLAS Sbjct 61 AKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLAS 120 Query 121 VSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAG 180 VSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAG Sbjct 121 VSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAG 180 Query 181 DLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLY 240 DLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLY Sbjct 181 DLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLY 240 Query 241 RPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWL 300 RPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWL Sbjct 241 RPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWL 300 Query 301 AMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYS 360 AMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYS Sbjct 301 AMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYS 360 Query 361 HSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYK 420 HSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYK Sbjct 361 HSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYK 420 Query 421 KAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKN 480 KAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKN Sbjct 421 KAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKN 480 Query 481 QTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 QTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 481 QTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 >gi|254363837|ref|ZP_04979883.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|308397502|ref|ZP_07492540.2| hypothetical protein TMLG_01607 [Mycobacterium tuberculosis SUMu012] gi|313657738|ref|ZP_07814618.1| hypothetical protein MtubKV_04926 [Mycobacterium tuberculosis KZN V2475] gi|134149351|gb|EBA41396.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|308366844|gb|EFP55695.1| hypothetical protein TMLG_01607 [Mycobacterium tuberculosis SUMu012] Length=537 Score = 1039 bits (2686), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/511 (99%), Positives = 510/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 27 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 86 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 87 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 146 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 147 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 206 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 207 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 266 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 267 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 326 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 327 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 386 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 387 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 446 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 447 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 506 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 507 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 537 >gi|15840326|ref|NP_335363.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CDC1551] gi|148660685|ref|YP_001282208.1| penicillin-binding protein 4 [Mycobacterium tuberculosis H37Ra] gi|148822116|ref|YP_001286870.1| hypothetical protein TBFG_10925 [Mycobacterium tuberculosis F11] 19 more sequence titles Length=562 Score = 1038 bits (2685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/511 (99%), Positives = 510/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 52 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 111 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 112 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 171 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 172 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 231 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 232 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 291 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 292 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 351 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 352 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 411 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 412 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 471 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 472 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 531 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 562 >gi|167967694|ref|ZP_02549971.1| hypothetical protein MtubH3_06508 [Mycobacterium tuberculosis H37Ra] gi|254549885|ref|ZP_05140332.1| hypothetical protein Mtube_05386 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|289446474|ref|ZP_06436218.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CPHL_A] gi|289573534|ref|ZP_06453761.1| penicillin-binding protein 4 [Mycobacterium tuberculosis K85] gi|297730411|ref|ZP_06959529.1| hypothetical protein MtubKR_04936 [Mycobacterium tuberculosis KZN R506] gi|289419432|gb|EFD16633.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CPHL_A] gi|289537965|gb|EFD42543.1| penicillin-binding protein 4 [Mycobacterium tuberculosis K85] Length=526 Score = 1038 bits (2684), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/511 (99%), Positives = 510/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 16 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 75 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 76 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 135 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 136 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 195 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 196 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 255 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 256 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 315 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 316 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 375 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 376 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 435 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 436 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 495 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 496 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 526 >gi|308374130|ref|ZP_07434983.2| hypothetical protein TMFG_02717 [Mycobacterium tuberculosis SUMu006] gi|308342849|gb|EFP31700.1| hypothetical protein TMFG_02717 [Mycobacterium tuberculosis SUMu006] Length=537 Score = 1038 bits (2684), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/511 (99%), Positives = 510/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 27 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 86 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 87 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 146 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 147 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 206 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 207 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 266 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 267 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 326 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 327 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 386 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 387 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 446 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 447 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 506 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 507 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 537 >gi|297633426|ref|ZP_06951206.1| hypothetical protein MtubK4_04856 [Mycobacterium tuberculosis KZN 4207] gi|306787945|ref|ZP_07426267.1| hypothetical protein TMDG_02679 [Mycobacterium tuberculosis SUMu004] gi|308231667|ref|ZP_07413370.2| hypothetical protein TMAG_00842 [Mycobacterium tuberculosis SUMu001] 17 more sequence titles Length=517 Score = 1038 bits (2684), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/511 (99%), Positives = 510/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 7 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 66 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 67 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 126 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 127 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 186 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 187 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 246 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 247 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 306 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 307 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 366 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 367 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 426 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 427 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 486 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 487 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 517 >gi|289442318|ref|ZP_06432062.1| penicillin-binding protein 4 [Mycobacterium tuberculosis T46] gi|289415237|gb|EFD12477.1| penicillin-binding protein 4 [Mycobacterium tuberculosis T46] Length=526 Score = 1037 bits (2681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 16 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 75 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 76 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 135 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 136 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 195 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 196 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 255 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 256 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 315 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 316 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 375 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AI ALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 376 AITALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 435 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 436 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 495 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 496 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 526 >gi|289749430|ref|ZP_06508808.1| conserved hypothetical protein [Mycobacterium tuberculosis T92] gi|289690017|gb|EFD57446.1| conserved hypothetical protein [Mycobacterium tuberculosis T92] Length=562 Score = 1036 bits (2680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 52 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 111 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 112 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 171 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 172 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 231 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 232 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 291 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 292 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 351 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 352 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 411 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AI ALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 412 AITALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 471 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 472 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 531 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 562 >gi|289756993|ref|ZP_06516371.1| penicillin-binding protein 4 [Mycobacterium tuberculosis T85] gi|289712557|gb|EFD76569.1| penicillin-binding protein 4 [Mycobacterium tuberculosis T85] Length=562 Score = 1036 bits (2680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 52 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 111 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 112 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 171 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 172 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 231 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 232 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 291 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 292 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 351 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 352 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 411 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 412 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 471 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYAND WGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 472 PAPSRPLNDYVGVYANDSWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 531 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 562 >gi|339293917|gb|AEJ46028.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CCDC5079] Length=537 Score = 1036 bits (2679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 27 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 86 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 87 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 146 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 147 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 206 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 207 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 266 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 267 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 326 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 327 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 386 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 387 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 446 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYAND WGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 447 PAPSRPLNDYVGVYANDSWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 506 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 507 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 537 >gi|294996388|ref|ZP_06802079.1| hypothetical protein Mtub2_18274 [Mycobacterium tuberculosis 210] gi|326904873|gb|EGE51806.1| penicillin binding protein [Mycobacterium tuberculosis W-148] Length=526 Score = 1036 bits (2678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 16 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 75 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 76 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 135 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 136 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 195 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 196 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 255 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 256 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 315 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 316 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 375 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 376 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 435 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYAND WGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 436 PAPSRPLNDYVGVYANDSWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 495 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 496 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 526 >gi|121636830|ref|YP_977053.1| hypothetical protein BCG_0959 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989301|ref|YP_002643988.1| hypothetical protein JTY_0929 [Mycobacterium bovis BCG str. Tokyo 172] gi|121492477|emb|CAL70945.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772414|dbj|BAH25220.1| hypothetical protein JTY_0929 [Mycobacterium bovis BCG str. Tokyo 172] gi|341600846|emb|CCC63517.1| conserved hypothetical protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=526 Score = 1035 bits (2677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 16 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 75 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 76 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 135 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 136 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 195 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 196 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 255 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 256 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 315 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 VYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 316 LVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 375 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 376 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 435 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 436 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 495 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 496 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 526 >gi|298524399|ref|ZP_07011808.1| penicillin-binding protein 4 [Mycobacterium tuberculosis 94_M4241A] gi|298494193|gb|EFI29487.1| penicillin-binding protein 4 [Mycobacterium tuberculosis 94_M4241A] Length=517 Score = 1035 bits (2676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 7 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 66 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 67 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 126 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 127 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 186 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 187 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 246 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 247 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 306 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PV TPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 307 PVCTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 366 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 367 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 426 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 427 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 486 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 487 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 517 >gi|31792095|ref|NP_854588.1| hypothetical protein Mb0931 [Mycobacterium bovis AF2122/97] gi|31617683|emb|CAD93792.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97] Length=516 Score = 1034 bits (2673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/511 (99%), Positives = 509/511 (99%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 6 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 65 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 66 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 125 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 126 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 185 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 186 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 245 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 246 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 305 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 VYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 306 LVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 365 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 366 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 425 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN Sbjct 426 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 485 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 486 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 516 >gi|340625918|ref|YP_004744370.1| hypothetical protein MCAN_09071 [Mycobacterium canettii CIPT 140010059] gi|340004108|emb|CCC43245.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=495 Score = 1004 bits (2597), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/495 (99%), Positives = 495/495 (100%), Gaps = 0/495 (0%) Query 38 LPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGV 97 +PDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGV Sbjct 1 MPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGV 60 Query 98 RDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDP 157 RDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDP Sbjct 61 RDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDP 120 Query 158 YVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVT 217 YVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVT Sbjct 121 YVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVT 180 Query 218 AAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQ 277 AAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQ Sbjct 181 AAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQ 240 Query 278 RDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPR 337 RDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPR Sbjct 241 RDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPR 300 Query 338 ARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPET 397 ARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPET Sbjct 301 ARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPET 360 Query 398 LTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYAN 457 LTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYAN Sbjct 361 LTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYAN 420 Query 458 DYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTL 517 DYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTL Sbjct 421 DYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTL 480 Query 518 NLEYYDADKLGTFTR 532 NLEYYDADKLGTFTR Sbjct 481 NLEYYDADKLGTFTR 495 >gi|339297557|gb|AEJ49667.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CCDC5180] Length=473 Score = 957 bits (2475), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/473 (99%), Positives = 472/473 (99%), Gaps = 0/473 (0%) Query 60 VAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLA 119 +AKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLA Sbjct 1 MAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLA 60 Query 120 SVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHA 179 SVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHA Sbjct 61 SVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHA 120 Query 180 GDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVL 239 GDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVL Sbjct 121 GDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVL 180 Query 240 YRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHW 299 YRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHW Sbjct 181 YRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHW 240 Query 300 LAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEY 359 LAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEY Sbjct 241 LAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEY 300 Query 360 SHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALY 419 SHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALY Sbjct 301 SHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALY 360 Query 420 KKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPK 479 KKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYAND WGPATVTYHDGQLRLSLGPK Sbjct 361 KKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDSWGPATVTYHDGQLRLSLGPK 420 Query 480 NQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 NQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR Sbjct 421 NQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 473 >gi|289568874|ref|ZP_06449101.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] gi|289542628|gb|EFD46276.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] Length=496 Score = 899 bits (2324), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/445 (99%), Positives = 443/445 (99%), Gaps = 0/445 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV Sbjct 52 LTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 111 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW Sbjct 112 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 171 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP Sbjct 172 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 231 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH Sbjct 232 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 291 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL Sbjct 292 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 351 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL Sbjct 352 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 411 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AI ALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN Sbjct 412 AITALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 471 Query 442 PAPSRPLNDYVGVYANDYWGPATVT 466 PAPSRPLNDYVGVYANDYWGPATVT Sbjct 472 PAPSRPLNDYVGVYANDYWGPATVT 496 >gi|240172194|ref|ZP_04750853.1| penicillin binding protein [Mycobacterium kansasii ATCC 12478] Length=518 Score = 811 bits (2094), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/511 (80%), Positives = 440/511 (87%), Gaps = 3/511 (0%) Query 25 CGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIV 84 CG +A GP S + PNE S + IPAGRID+AVAK+DGLV ELM+ +GIPGMAVA+V Sbjct 8 CGPAQRASGPTSARSNVPPNEVSGLDIPAGRIDEAVAKLDGLVAELMKTSGIPGMAVAVV 67 Query 85 HGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTP 144 HGGKTLYAKGFG++D K GPDN+VDADTVFQLASVSKSVGATVVAH V +VVTWDTP Sbjct 68 HGGKTLYAKGFGIKDASKTDGPDNRVDADTVFQLASVSKSVGATVVAHEVGTHVVTWDTP 127 Query 145 VVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAP 204 VV+KLPWF L D YVT VTIADLYSHRSGLPDHAGD LEDLGYD +QVLQRLKYLPLAP Sbjct 128 VVAKLPWFELGDAYVTSHVTIADLYSHRSGLPDHAGDPLEDLGYDGQQVLQRLKYLPLAP 187 Query 205 FRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVN 264 FRISYAYTNFGVTAAAEAVAAAAG+ W +LSDEVLYRPLGM STSSRF DFLARPNHAV Sbjct 188 FRISYAYTNFGVTAAAEAVAAAAGKPWAELSDEVLYRPLGMTSTSSRFADFLARPNHAVT 247 Query 265 HVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVY 324 H+KVAD+WEAR+QRDPDAQ+PAGGVSSSLNDMTHWL MVLA+G YNG++ITSPEALLP Sbjct 248 HIKVADKWEARFQRDPDAQTPAGGVSSSLNDMTHWLTMVLANGTYNGQQITSPEALLPAI 307 Query 325 TPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAII 384 TPQVIS P+ARA YGYGFNV V SSGRT+Y HSG FGLGAA NF VLPSEDLAII Sbjct 308 TPQVISTPARLPKARAGTYGYGFNVSVNSSGRTQYGHSGGFGLGAATNFTVLPSEDLAII 367 Query 385 ALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAP 444 ALTNA P GVPETLTAEFMDLVQYGQVREDWA LYK+ APLN G+LVGKQ P +PAP Sbjct 368 ALTNAAPYGVPETLTAEFMDLVQYGQVREDWATLYKQQLAPLNNPEGALVGKQPPVSPAP 427 Query 445 SRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALP 504 +RPL+DYVGVYANDYWGPATVT DGQL+LSLGPKNQTF LTHWD DTFTF LSTENALP Sbjct 428 ARPLSDYVGVYANDYWGPATVTERDGQLQLSLGPKNQTFTLTHWDADTFTFPLSTENALP 487 Query 505 GSISKATFAG---DTLNLEYYDADKLGTFTR 532 GSISKA F+G TLNLEYYDADKLGTFTR Sbjct 488 GSISKAVFSGFPVATLNLEYYDADKLGTFTR 518 >gi|183984590|ref|YP_001852881.1| penicillin binding protein [Mycobacterium marinum M] gi|183177916|gb|ACC43026.1| conserved hypothetical penicillin binding protein [Mycobacterium marinum M] Length=527 Score = 806 bits (2082), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/509 (79%), Positives = 438/509 (87%), Gaps = 0/509 (0%) Query 24 GCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAI 83 GC PPS PNE S I IP GRID+AVAKVDGLV ELM++TGIPGMAVAI Sbjct 19 GCAPKQSISNPPSTPSQLPPNEVSGIDIPPGRIDEAVAKVDGLVAELMKSTGIPGMAVAI 78 Query 84 VHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDT 143 VHGGKTLYAKGFGVRDV KG G DNKVD DTVFQLAS+SK +GATVVAH V+ NVV+WDT Sbjct 79 VHGGKTLYAKGFGVRDVSKGDGQDNKVDTDTVFQLASMSKPIGATVVAHEVSTNVVSWDT 138 Query 144 PVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLA 203 PVVSKLP FAL DPYVT TIADLYSHRSGLPDHAGD LEDLGYD QVL+RLKYLPL Sbjct 139 PVVSKLPEFALSDPYVTDHATIADLYSHRSGLPDHAGDALEDLGYDTTQVLERLKYLPLD 198 Query 204 PFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAV 263 PFRISYAYTNFGVTAAA+AVAAAAG++W DLS+EVLYRPLGM STSSRF DFLARPNHAV Sbjct 199 PFRISYAYTNFGVTAAADAVAAAAGKAWPDLSEEVLYRPLGMTSTSSRFADFLARPNHAV 258 Query 264 NHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPV 323 NH+KV DRWEAR+QRDPDAQ+PAGGVSSSLNDM HWL MVLA+G YNG++I SPEALLP Sbjct 259 NHIKVGDRWEARFQRDPDAQTPAGGVSSSLNDMAHWLTMVLANGEYNGQQIVSPEALLPA 318 Query 324 YTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAI 383 TPQVIS SP+ARA FYG+GF V V+S+GRT+Y HSGAFGLGAA NFVVLPSED+AI Sbjct 319 ITPQVISSAARSPKARAGFYGHGFTVSVSSAGRTQYGHSGAFGLGAATNFVVLPSEDIAI 378 Query 384 IALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPA 443 +ALTNA P G+PE LTA+FMDLVQYG+VREDW LY++ +P+N GSLVGKQ P NP Sbjct 379 VALTNAAPYGIPEALTAQFMDLVQYGEVREDWTNLYRQQMSPINTPEGSLVGKQPPVNPE 438 Query 444 PSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENAL 503 P+RP +DYVGVYANDYWGPATVT DGQL+LS+GPKNQTFDLTHWDGDTFTF LSTENAL Sbjct 439 PARPPSDYVGVYANDYWGPATVTERDGQLQLSMGPKNQTFDLTHWDGDTFTFALSTENAL 498 Query 504 PGSISKATFAGDTLNLEYYDADKLGTFTR 532 PGSISKATFAGDTLNLEY+D++KLGTFTR Sbjct 499 PGSISKATFAGDTLNLEYFDSNKLGTFTR 527 >gi|342860513|ref|ZP_08717164.1| hypothetical protein MCOL_16601 [Mycobacterium colombiense CECT 3035] gi|342132168|gb|EGT85409.1| hypothetical protein MCOL_16601 [Mycobacterium colombiense CECT 3035] Length=527 Score = 774 bits (1999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/511 (75%), Positives = 428/511 (84%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGS GPPS + D PN+ S + IPAGRID AVAKVDGLV +LM++TGIPGMAV Sbjct 17 LTGCGSAQPTAGPPSTVSDVPPNQVSGVSIPAGRIDAAVAKVDGLVNDLMKSTGIPGMAV 76 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 A+VHGGK LYAKGFG++D +G G DN+VDADTVFQLASVSKSVGATV+AH V+DNVV W Sbjct 77 AVVHGGKVLYAKGFGIKDASRGQGQDNRVDADTVFQLASVSKSVGATVIAHEVSDNVVAW 136 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTP+ SKL WF L DPYVT VT+ D+YSHRSGLPDHAGD LEDLGYDRRQ L+RLKYLP Sbjct 137 DTPIASKLGWFTLSDPYVTSHVTVGDVYSHRSGLPDHAGDKLEDLGYDRRQTLERLKYLP 196 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 L PFRISYAYTN+G+TA AEAVAAAAG+ WEDL DE LYRPLGM STSSRF DF ARPNH Sbjct 197 LDPFRISYAYTNYGITAGAEAVAAAAGRPWEDLCDEALYRPLGMTSTSSRFADFAARPNH 256 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNH+K+ D+W+AR+QR+PDAQSPAGGVSSS+NDM WL M+L +G +NG+RITSPEALL Sbjct 257 AVNHIKIDDKWQARFQRNPDAQSPAGGVSSSVNDMARWLLMLLGNGTHNGQRITSPEALL 316 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 P +PQ++S +P+AR FYGYGFN V SSGRTEYSHSGAF LGAA NFVVLPSEDL Sbjct 317 PAISPQMVSAPAKTPQARTGFYGYGFNSSVDSSGRTEYSHSGAFDLGAATNFVVLPSEDL 376 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNA P G+PETLTAEFMDLVQYGQVREDW LYKKA LN GSLVGKQ P + Sbjct 377 AIIALTNAAPYGIPETLTAEFMDLVQYGQVREDWGPLYKKAIGWLNNPVGSLVGKQPPVS 436 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAP+RPL DY G YA+DYWGPA VT DG L+L++GPKN+T LTHWDGDTFTF L+ EN Sbjct 437 PAPARPLGDYAGTYASDYWGPAVVTERDGALQLAMGPKNRTTTLTHWDGDTFTFALTDEN 496 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 A PG+ISKA FAG+TLNLEYYD+DKLGTFTR Sbjct 497 APPGTISKAVFAGNTLNLEYYDSDKLGTFTR 527 >gi|296169665|ref|ZP_06851283.1| beta-lactamase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895662|gb|EFG75358.1| beta-lactamase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=525 Score = 763 bits (1971), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/511 (77%), Positives = 432/511 (85%), Gaps = 1/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCG PP+ L DA PNE S + IPAGRIDDAVAKVDGLV +LM++TG+PGMAV Sbjct 16 ITGCGPAQPVSRPPA-LSDAPPNEVSGLAIPAGRIDDAVAKVDGLVDDLMKSTGVPGMAV 74 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGK LYAKGFGV+DV +G G DNKVDADTVFQLASVSKSVGATVVAH VTDNVV W Sbjct 75 AIVHGGKVLYAKGFGVKDVSRGRGQDNKVDADTVFQLASVSKSVGATVVAHEVTDNVVAW 134 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPV +KLPWF L DPYV+G VTIADLYSHRSGLPDHAGD LEDLGY RRQ L+RLKYLP Sbjct 135 DTPVAAKLPWFTLGDPYVSGHVTIADLYSHRSGLPDHAGDKLEDLGYGRRQTLERLKYLP 194 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFR+SYAYTN+GVTAAAEAVAAAAG+ WEDLSDE LYRPLGM STSSRF DF+ARPNH Sbjct 195 LAPFRVSYAYTNYGVTAAAEAVAAAAGKPWEDLSDEALYRPLGMTSTSSRFADFVARPNH 254 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKV D+WEAR QRDPD QSPAGGVSSS++DM WL M+L +G YNGRRI +PEALL Sbjct 255 AVNHVKVGDKWEARLQRDPDPQSPAGGVSSSVDDMARWLMMLLGNGTYNGRRIVAPEALL 314 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 P +PQ++S +P+AR FYGYGFN V SSGRTEYSHSGAF LGAA NFVV+P+EDL Sbjct 315 PATSPQMVSSPAKTPKARTGFYGYGFNASVDSSGRTEYSHSGAFALGAATNFVVMPAEDL 374 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 IIALTN P G+PETLTA+FMDLVQYGQ+REDW ALY+KA LN GSLVGKQ PAN Sbjct 375 GIIALTNGAPYGIPETLTAQFMDLVQYGQIREDWGALYQKAIGWLNNPEGSLVGKQPPAN 434 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAP+RPL DY GVYA+DYWGPA VT HDG L+L++GPKN+T LTHWDGDTFTF L+ EN Sbjct 435 PAPARPLRDYAGVYASDYWGPAVVTEHDGTLQLAMGPKNRTVTLTHWDGDTFTFGLTDEN 494 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 A PG++SKA F G TLNLEYYD+DKLGTFTR Sbjct 495 APPGTVSKAVFFGATLNLEYYDSDKLGTFTR 525 >gi|254822960|ref|ZP_05227961.1| penicillin-binding protein 4 [Mycobacterium intracellulare ATCC 13950] Length=525 Score = 756 bits (1953), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/511 (74%), Positives = 425/511 (84%), Gaps = 0/511 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGS G PS L D PN+ + + IPAGRIDDAVAK+DGL G+LM+NTG+PGMAV Sbjct 15 LTGCGSAQPTAGAPSTLSDVPPNQVAGVAIPAGRIDDAVAKIDGLAGDLMKNTGVPGMAV 74 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 A+VHGGK LYAKGFGV+DV KG G NKVDADTVFQLASVSKSVGATV+AH V+D+VV W Sbjct 75 AVVHGGKVLYAKGFGVKDVSKGEGQGNKVDADTVFQLASVSKSVGATVIAHEVSDHVVAW 134 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPV +KLPWF L DPYV+ VT+AD+YSHRSGLPDHAGD LEDLGYDRRQ L+RL+YLP Sbjct 135 DTPVAAKLPWFTLGDPYVSSHVTVADVYSHRSGLPDHAGDKLEDLGYDRRQTLERLRYLP 194 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 LAPFRISYAYTN+G+TA AEAVAAAAG+SWEDLSDE LYRPL M STSSRF DFLARPNH Sbjct 195 LAPFRISYAYTNYGITAGAEAVAAAAGKSWEDLSDEALYRPLKMTSTSSRFADFLARPNH 254 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNHVKVAD+WEAR+QRDPD QSPAGGVSSS+NDM WL M+L +G ++GRRI +PE LL Sbjct 255 AVNHVKVADKWEARFQRDPDPQSPAGGVSSSVNDMARWLMMLLGNGTHDGRRIAAPEDLL 314 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 P +PQ +S +P+AR FYGYGFN V SSGRTEYSHSGAF LGAA NFVV+PSED+ Sbjct 315 PAISPQTVSTPATTPKARTGFYGYGFNASVDSSGRTEYSHSGAFALGAATNFVVMPSEDV 374 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 IIALTN P G+PETLTAEFMDLVQYGQ+REDW LY+KA LN GSLVGKQ P N Sbjct 375 GIIALTNGAPYGIPETLTAEFMDLVQYGQIREDWGPLYQKAIGWLNNPVGSLVGKQPPPN 434 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAP++PL DY GVYA+DYWGPA VT HDG L L++GPKN T LTHWDGDTFTF L+ EN Sbjct 435 PAPAKPLRDYAGVYASDYWGPAVVTEHDGALHLAMGPKNHTVALTHWDGDTFTFPLTDEN 494 Query 502 ALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 A PG+ISKA F+ DTLNLEYYD +KLGTF R Sbjct 495 APPGTISKAVFSNDTLNLEYYDTEKLGTFAR 525 >gi|118463767|ref|YP_880286.1| penicillin-binding protein 4 [Mycobacterium avium 104] gi|254773917|ref|ZP_05215433.1| penicillin-binding protein 4 [Mycobacterium avium subsp. avium ATCC 25291] gi|118165054|gb|ABK65951.1| penicillin-binding protein 4 [Mycobacterium avium 104] Length=528 Score = 736 bits (1900), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/514 (73%), Positives = 427/514 (84%), Gaps = 3/514 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGS Q G P D SPN+ SA+ IPAGRID+AVAKVDGLV +LM+++GIPGMAV Sbjct 15 LTGCGSAQQPAGAPPRPSDVSPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAV 74 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGK LYAKGFGV+DV G G DN VD DTVFQLASVSKSVGATVVAH V+D+VV W Sbjct 75 AIVHGGKVLYAKGFGVKDVTSGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSDHVVGW 134 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVS LPWFAL DPYVTG VT+ DLYSHRSGLPDHAGD LEDLGY RRQ+ +RL+ LP Sbjct 135 DTPVVSTLPWFALGDPYVTGHVTVGDLYSHRSGLPDHAGDKLEDLGYGRRQICERLRLLP 194 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 L PFR SYAYTN+G+TAAAEAVAAAAG++WE+LSDEVLYRPLGM STSSRF DFLARPN Sbjct 195 LRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTSTSSRFADFLARPNR 254 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNH+K+ D W+AR+QR+PDAQSPAGGVSSS+ DM WL M+L +G ++G+ I SPEALL Sbjct 255 AVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVRDMARWLMMLLDNGTHDGQHIASPEALL 314 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 P +PQV+S +P+AR FYGYGFN V +SGRTEYSHSGAF LGAA NFVVLPSEDL Sbjct 315 PALSPQVVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDLGAATNFVVLPSEDL 374 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNA P G+PETLTAEFMDLVQYGQ+REDWAALY+KA LN GSLVGKQ P+ Sbjct 375 AIIALTNAAPYGIPETLTAEFMDLVQYGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSA 434 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAP+RPL DY GVYANDYWGPA +T HDG L+L++GP+++T LTHWDGDTFTF L+ EN Sbjct 435 PAPARPLRDYTGVYANDYWGPAVITEHDGALQLTMGPQHRTATLTHWDGDTFTFPLTGEN 494 Query 502 ALPGSISKATFAGD---TLNLEYYDADKLGTFTR 532 A PG++S ATF G LNLEYYD D+LGTFTR Sbjct 495 APPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR 528 >gi|41406940|ref|NP_959776.1| hypothetical protein MAP0842 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395290|gb|AAS03159.1| hypothetical protein MAP_0842 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461278|gb|EGO40152.1| penicillin-binding protein, beta-lactamase class C [Mycobacterium avium subsp. paratuberculosis S397] Length=528 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/514 (73%), Positives = 427/514 (84%), Gaps = 3/514 (0%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAV 81 + GCGS Q G P D PN+ SA+ IPAGRID+AVAKVDGLV +LM+++GIPGMAV Sbjct 15 LTGCGSAQQPAGAPPRPSDVPPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAV 74 Query 82 AIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTW 141 AIVHGGK LYAKGFGV+DV +G G DN VD DTVFQLASVSKSVGATVVAH V+D+VV W Sbjct 75 AIVHGGKVLYAKGFGVKDVTRGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSDHVVGW 134 Query 142 DTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLP 201 DTPVVS LPWFAL DPYVTG VT+ DLYSHRSGLPDHAGD LEDLGY RRQ+ +RL+ LP Sbjct 135 DTPVVSTLPWFALGDPYVTGHVTVGDLYSHRSGLPDHAGDKLEDLGYGRRQICERLRLLP 194 Query 202 LAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNH 261 L PFR SYAYTN+G+TAAAEAVAAAAG++WE+LSDEVLYRPLGM STSSRF DFLARPN Sbjct 195 LRPFRNSYAYTNYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTSTSSRFADFLARPNR 254 Query 262 AVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALL 321 AVNH+K+ D W+AR+QR+PDAQSPAGGVSSS++DM WL M+L +G ++G+ I SPEALL Sbjct 255 AVNHIKIGDSWQARFQRNPDAQSPAGGVSSSVHDMARWLMMLLDNGTHDGQHIASPEALL 314 Query 322 PVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDL 381 P +PQV+S +P+AR FYGYGFN V +SGRTEYSHSGAF LGAA NFVVLPSEDL Sbjct 315 PALSPQVVSAPATTPKARTGFYGYGFNTSVDASGRTEYSHSGAFDLGAATNFVVLPSEDL 374 Query 382 AIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPAN 441 AIIALTNA P G+PETLTAEFMDLVQYGQ+REDWAALY+KA LN GSLVGKQ P+ Sbjct 375 AIIALTNAAPNGIPETLTAEFMDLVQYGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSA 434 Query 442 PAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTEN 501 PAP+RPL DY GVYANDYWGPA + HDG L+L++GP+++T LTHWDGDTFTF L+ EN Sbjct 435 PAPARPLRDYTGVYANDYWGPAVINEHDGALQLTMGPQHRTATLTHWDGDTFTFPLTGEN 494 Query 502 ALPGSISKATFAGD---TLNLEYYDADKLGTFTR 532 A PG++S ATF G LNLEYYD D+LGTFTR Sbjct 495 APPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR 528 >gi|118470511|ref|YP_889871.1| penicillin-binding protein 4 [Mycobacterium smegmatis str. MC2 155] gi|118171798|gb|ABK72694.1| penicillin-binding protein 4 [Mycobacterium smegmatis str. MC2 155] Length=538 Score = 617 bits (1590), Expect = 2e-174, Method: Compositional matrix adjust. Identities = 324/517 (63%), Positives = 386/517 (75%), Gaps = 7/517 (1%) Query 22 VNGCG------STHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTG 75 V+GC ++ P D P A+ +P +++AVAK+DG+ +LM+++G Sbjct 23 VSGCAGGDDTADAQRSAQPSQTFADEPPPLVPAMALPENAVENAVAKLDGIAEDLMRSSG 82 Query 76 IPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVT 135 IPGMAVA+VHGGKT+YAKGFGVRDV G N+VD DTVFQLAS+SK + ATVVAH V Sbjct 83 IPGMAVAVVHGGKTVYAKGFGVRDVRNGDVESNRVDPDTVFQLASLSKPIAATVVAHQVG 142 Query 136 DNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQ 195 + WDTPVV LPWFAL DP T VT+ DL++HRSGLPDHAGD LEDLGYDRR +L+ Sbjct 143 TGAIGWDTPVVEHLPWFALSDPVTTRMVTVGDLFAHRSGLPDHAGDQLEDLGYDRRYILE 202 Query 196 RLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDF 255 L+ LPL PFR SYAYTNFG+TAAAEAVAAAAG+SWEDL+ +VLYRPLGM STSSRF D+ Sbjct 203 HLRALPLDPFRNSYAYTNFGLTAAAEAVAAAAGRSWEDLARDVLYRPLGMDSTSSRFADY 262 Query 256 LARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRIT 315 A N AV H++V R+E +Y R+ DAQ+PAGGVS+S++DMT WLAMVL DGV+ G RI Sbjct 263 EATQNRAVGHIRVDGRYEPQYVRNADAQTPAGGVSASVDDMTRWLAMVLGDGVFEGERIV 322 Query 316 SPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVV 375 LLP TPQV+S P R+ FYGYGFNVG TS+ RT+ SHSGAF LGAA NFV+ Sbjct 323 EESTLLPAITPQVVSDRASQPAMRSGFYGYGFNVGTTSAARTQLSHSGAFELGAATNFVI 382 Query 376 LPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVG 435 LPS D+ I+ALTN P G+PETLTAEF DLVQ+G+VR+DW LY AFA ++ G LVG Sbjct 383 LPSADVGIVALTNGTPAGIPETLTAEFADLVQFGEVRQDWRKLYADAFASMDGPEGELVG 442 Query 436 KQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTF 495 K+ PA PAP+RPL DYVGVY NDYWGPATVT DG L+L+LGPK + LTHWDGD FTF Sbjct 443 KKPPAVPAPARPLPDYVGVYRNDYWGPATVTEQDGALQLALGPKFKA-RLTHWDGDVFTF 501 Query 496 TLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +ENA PG+ISKATFAGD L LEY+D D GTFTR Sbjct 502 RFVSENAPPGTISKATFAGDKLTLEYFDEDGTGTFTR 538 >gi|145222347|ref|YP_001133025.1| beta-lactamase [Mycobacterium gilvum PYR-GCK] gi|315442780|ref|YP_004075659.1| penicillin-binding protein, beta-lactamase class C [Mycobacterium sp. Spyr1] gi|145214833|gb|ABP44237.1| beta-lactamase [Mycobacterium gilvum PYR-GCK] gi|315261083|gb|ADT97824.1| penicillin-binding protein, beta-lactamase class C [Mycobacterium sp. Spyr1] Length=531 Score = 614 bits (1583), Expect = 1e-173, Method: Compositional matrix adjust. Identities = 309/519 (60%), Positives = 379/519 (74%), Gaps = 6/519 (1%) Query 19 VADVNGCG--STHQALGP---PSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQN 73 VA + GC ST A P L D P A+ +P + +AVAK+DGL +LM Sbjct 14 VALLAGCAAESTEPAASSTPAPGPLSDVPPPLVPAMPLPENAVANAVAKLDGLAEDLMST 73 Query 74 TGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHA 133 +G+PGMAVA+VH GKT+YAKGFGV++ + P+N+VDADTVFQLAS+SK + ATVVA Sbjct 74 SGVPGMAVAVVHQGKTVYAKGFGVKNNTQSDSPENRVDADTVFQLASLSKPLSATVVAAL 133 Query 134 VTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQV 193 V + V WDTPVVS+LPWFAL DP T VT+ D++SHRSGLPDHAGD LEDLGYDRRQV Sbjct 134 VGQDQVGWDTPVVSRLPWFALSDPTTTQMVTVGDMFSHRSGLPDHAGDQLEDLGYDRRQV 193 Query 194 LQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFT 253 L RL+ LPLA FR SYAYTNFG+TA AEAVA AG+SWEDL+ + L RPLGMG TS RF Sbjct 194 LDRLRQLPLAQFRTSYAYTNFGLTAGAEAVATGAGKSWEDLAADTLLRPLGMGVTSYRFE 253 Query 254 DFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRR 313 D+ +R + AV H+++ D ++ RY RD AQSPAGG SSS+NDMT W+AMVLA+G ++G Sbjct 254 DYASRRDRAVGHIRIDDGYQPRYVRDAQAQSPAGGASSSVNDMTRWMAMVLAEGRHDGNA 313 Query 314 ITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANF 373 + P+ALLP +PQV S P P R FYGYGFNVG TS+ RT+ SHSGAF LGAA N Sbjct 314 LIDPQALLPAISPQVTSAPPTEPAMRPGFYGYGFNVGTTSAARTQLSHSGAFELGAATNV 373 Query 374 VVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSL 433 + LPS D+AIIALTNA P GVPETLTA+F DLVQ+G++R+DWAALY KAFA +++ GSL Sbjct 374 LFLPSADVAIIALTNATPTGVPETLTAQFADLVQFGEIRQDWAALYGKAFADMDKPVGSL 433 Query 434 VGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTF 493 VG+Q N PL+ Y GVY NDYWGPATVT DG+L+L+LGP+ F+L WDG+ F Sbjct 434 VGQQRHVNAQTHGPLDSYTGVYGNDYWGPATVTERDGRLQLALGPRG-VFELDAWDGNVF 492 Query 494 TFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 F +S+ENA PG++S ATF G L LEY+D + G F R Sbjct 493 VFPVSSENAPPGTVSAATFDGGALTLEYFDQEGNGVFVR 531 >gi|120405939|ref|YP_955768.1| beta-lactamase [Mycobacterium vanbaalenii PYR-1] gi|119958757|gb|ABM15762.1| beta-lactamase [Mycobacterium vanbaalenii PYR-1] Length=531 Score = 612 bits (1577), Expect = 7e-173, Method: Compositional matrix adjust. Identities = 305/514 (60%), Positives = 374/514 (73%), Gaps = 6/514 (1%) Query 24 GCGS-----THQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPG 78 GCG+ + PS D P A+ +P + DAVAK+DGL +LM +GIPG Sbjct 19 GCGTEGAEPAASSTPAPSPASDVPPPLVPAMPLPENAVADAVAKLDGLAEDLMSKSGIPG 78 Query 79 MAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNV 138 MAVA+VHGGK +YAKGFGVR+ P N+VDADTVFQLAS+SK + AT VA V N Sbjct 79 MAVAVVHGGKAVYAKGFGVRNNTMSDEPHNEVDADTVFQLASLSKPLSATAVAALVGQNQ 138 Query 139 VTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLK 198 V+WDTP+VS+LPWFAL DP VT VT+ D++SHRSGLPDHAGD LEDLGYDRRQVL+RL+ Sbjct 139 VSWDTPIVSRLPWFALSDPAVTQMVTVGDMFSHRSGLPDHAGDQLEDLGYDRRQVLERLR 198 Query 199 YLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLAR 258 LPL FR SYAYTNFG+TA AEAVA AG+SWEDL+ + L RPLGMG+TS RF+D+ +R Sbjct 199 QLPLDQFRTSYAYTNFGLTAGAEAVATGAGKSWEDLAADTLLRPLGMGATSYRFSDYESR 258 Query 259 PNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPE 318 + AV H+++ ++ R+ RD AQSPAGG SSS+NDMT W+AMVLADG ++G ++ P Sbjct 259 RDRAVGHIRIDGGYQPRFVRDAQAQSPAGGASSSVNDMTRWMAMVLADGRHDGNQLIDPT 318 Query 319 ALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPS 378 ALLP TPQV S P R+ FYGYGFNVG TS+ RT+ SHSGAF LGAA N + LPS Sbjct 319 ALLPAITPQVTSSRGSEPAMRSGFYGYGFNVGTTSAARTQLSHSGAFELGAATNVLFLPS 378 Query 379 EDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQS 438 D+AI+ALTNA P G+PETLTA+F DLVQ+G++R+DW ALY KAF +++ GSLVG+Q Sbjct 379 ADVAIVALTNATPTGIPETLTAQFADLVQFGEIRQDWYALYAKAFEDMDKPVGSLVGQQR 438 Query 439 PANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLS 498 PAN PL Y GVY NDYWGPATVT DG L L+LGP+ F L WDG+ FTF +S Sbjct 439 PANAQAHGPLAAYTGVYRNDYWGPATVTERDGHLELALGPRG-VFKLQPWDGNVFTFPVS 497 Query 499 TENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +ENA PG++S ATF +L LEY+D + G FTR Sbjct 498 SENAPPGTVSAATFDAGSLTLEYFDDEGKGVFTR 531 >gi|111022825|ref|YP_705797.1| hypothetical protein RHA1_ro05862 [Rhodococcus jostii RHA1] gi|110822355|gb|ABG97639.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=532 Score = 606 bits (1563), Expect = 3e-171, Method: Compositional matrix adjust. Identities = 322/521 (62%), Positives = 386/521 (75%), Gaps = 19/521 (3%) Query 22 VNGCGSTHQALGPPSGLPDASPNERSA----------IQIPAGRIDDAVAKVDGLVGELM 71 V GCGS G DASP S+ + IP G+IDDAV ++D L ELM Sbjct 21 VTGCGSGSDDAGS-----DASPTSESSQPPNPGTVAGVDIPDGQIDDAVGRLDELANELM 75 Query 72 QNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVA 131 +++G+PGMA+A+VHGG+T+YAKGFGVR+ G D KVDADTVFQLAS+SKSVG+TVVA Sbjct 76 ESSGLPGMAIAVVHGGQTVYAKGFGVREAGT----DQKVDADTVFQLASMSKSVGSTVVA 131 Query 132 HAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRR 191 H V VV WDTPVVSK P FAL DP+VT VT+ DLYSHRSGLPDHAGDLLEDLGY+++ Sbjct 132 HQVDAGVVGWDTPVVSKSPGFALADPWVTEHVTVGDLYSHRSGLPDHAGDLLEDLGYNQQ 191 Query 192 QVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSR 251 QVL +L+ PL PFRI+Y YTNFG+TAAAEAVAAA+G W LS++ +YRPLGM STSSR Sbjct 192 QVLDKLRLEPLNPFRITYEYTNFGLTAAAEAVAAASGTDWATLSEQTIYRPLGMSSTSSR 251 Query 252 FTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNG 311 F D+ AR + AV H V ++ A RDPDAQSPAGGVSSS+NDM WLAM+LADG + G Sbjct 252 FADYQARSDRAVAHQLVDGKYVADAVRDPDAQSPAGGVSSSVNDMGKWLAMLLADGTFEG 311 Query 312 RRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAA 371 + I SPEALLP +PQ++S P S +R YGYGFNV T +GR SHSG F LG A Sbjct 312 KEIVSPEALLPAVSPQMVSSPPRSMDSRPGSYGYGFNVSTTPAGRVSLSHSGGFQLGVAT 371 Query 372 NFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAG 431 NFV +PS D+AI+ALTN PIG+PE+LTAEF DLVQ+G++REDW +LY++A AP++E G Sbjct 372 NFVAIPSADVAIVALTNGSPIGIPESLTAEFADLVQFGEIREDWRSLYRQAIAPMDEPEG 431 Query 432 SLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGD 491 SLVG+ +PANPAP +PL Y G Y N YWGPA VT +G L L LGP QTF LTHWDGD Sbjct 432 SLVGQTAPANPAPPQPLPTYAGTYGNPYWGPAVVTESNGALTLQLGPAGQTFPLTHWDGD 491 Query 492 TFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 TFTFT ENA PG+ISKATFAG+ + LE+YD + GTF R Sbjct 492 TFTFTPRGENAPPGTISKATFAGNNVTLEFYDTEGRGTFVR 532 >gi|226365333|ref|YP_002783116.1| penicillin-binding protein [Rhodococcus opacus B4] gi|226243823|dbj|BAH54171.1| putative penicillin-binding protein [Rhodococcus opacus B4] Length=537 Score = 598 bits (1543), Expect = 5e-169, Method: Compositional matrix adjust. Identities = 319/533 (60%), Positives = 383/533 (72%), Gaps = 16/533 (3%) Query 1 LATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAV 60 L T CG D +D +G T ++ GPP+ P S + IP GRID+AV Sbjct 20 LVTGCGSDADDAGS-----SDASGANPTSESSGPPN------PAAFSGVDIPDGRIDEAV 68 Query 61 AKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLAS 120 ++D L ELM+++G+PGMAVA+VHGG+T+YAKGFGVR+ G D KVDADTVFQLAS Sbjct 69 GRLDELANELMESSGLPGMAVAVVHGGQTVYAKGFGVREAGT----DQKVDADTVFQLAS 124 Query 121 VSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAG 180 +SK VG+TVVA V VV WDTPVVSKLP FAL DP+VT VT+ DLYSHRSGLPDHAG Sbjct 125 MSKPVGSTVVARQVDAGVVGWDTPVVSKLPGFALADPWVTEHVTVGDLYSHRSGLPDHAG 184 Query 181 DLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLY 240 D LEDLGYD++QVL +L+ PL PFRI+Y YTNFG+TAAAEAVAAA+G W LS++ +Y Sbjct 185 DHLEDLGYDQQQVLDKLRLDPLNPFRITYDYTNFGLTAAAEAVAAASGTDWATLSEQAIY 244 Query 241 RPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWL 300 PLGM STSSRF D+ AR + AV H V ++ A R+PDAQSPAGGVSSS+NDM WL Sbjct 245 GPLGMSSTSSRFADYEARSDRAVAHQLVDGKYVADAVRNPDAQSPAGGVSSSVNDMGRWL 304 Query 301 AMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYS 360 AM+LADG + G+ I SPEAL P +PQ++S P S +R YGYGFNV TS+GR S Sbjct 305 AMLLADGTFEGKEIVSPEALQPAVSPQIVSSPPRSMDSRPGSYGYGFNVSTTSAGRVSLS 364 Query 361 HSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYK 420 HSGAF LG A NFV +PS D+AI+ALTN PIG+PETLTAEF DLVQYG++REDW +LY+ Sbjct 365 HSGAFQLGVATNFVAIPSADVAIVALTNGSPIGIPETLTAEFADLVQYGEIREDWRSLYR 424 Query 421 KAFAPLNELAGSLVG-KQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPK 479 +A +P+ + GSLVG P +PL Y G Y N YWGPA VT +G L L LGP Sbjct 425 QAISPMLDPEGSLVGQTAPANPAPPQQPLPTYAGTYDNPYWGPAIVTESNGALSLGLGPA 484 Query 480 NQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 QT+ LTHWDGDTFTFTLS ENA PG+ISKATF G+ + LEYYD + GTF R Sbjct 485 GQTYPLTHWDGDTFTFTLSGENAPPGTISKATFTGNDVTLEYYDTEGRGTFVR 537 >gi|126437375|ref|YP_001073066.1| beta-lactamase [Mycobacterium sp. JLS] gi|126237175|gb|ABO00576.1| beta-lactamase [Mycobacterium sp. JLS] Length=533 Score = 597 bits (1540), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 316/515 (62%), Positives = 379/515 (74%), Gaps = 10/515 (1%) Query 24 GCGST----HQALGPPSGLP--DASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIP 77 GC S Q+ PP P D P +A+ +P +D AV ++DG+V EL+ +GIP Sbjct 23 GCDSAPTEEAQSTQPPPATPQSDVPPPLVAAVPLPDNAVDKAVGQLDGMVEELLAKSGIP 82 Query 78 GMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDN 137 GMAVA+VHGGKT+YAKGFGV DV G KVD DTVFQLAS+SK +GATVVAH V Sbjct 83 GMAVAVVHGGKTVYAKGFGVTDVKTGA----KVDPDTVFQLASMSKPLGATVVAHQVGRG 138 Query 138 VVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRL 197 + WDTP+VSKLPWFAL DP VT VT+ DLYSHRSGLPDHAGDLLEDLGYDRR +L+RL Sbjct 139 AIGWDTPIVSKLPWFALSDPAVTQMVTVGDLYSHRSGLPDHAGDLLEDLGYDRRAILERL 198 Query 198 KYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLA 257 + LPLAPFR SYAYTNFG+TAAAEAVA +AG+ WE LS+EVLYRPLGM STSSRF D+ Sbjct 199 RALPLAPFRDSYAYTNFGLTAAAEAVATSAGKPWETLSEEVLYRPLGMNSTSSRFADYEK 258 Query 258 RPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSP 317 RP+ AV H+ V R+E Y R+ DA+ PAGG SSS+ND+T WLAMVLADG G+++ P Sbjct 259 RPDRAVGHIHVDGRYEPLYVRNADAEGPAGGASSSVNDLTKWLAMVLADGKAGGQQLVEP 318 Query 318 EALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLP 377 +ALLP TPQ +S P R FYG+GFNVG +S+ R E SHSGAF LG+ NFV+LP Sbjct 319 DALLPAVTPQSVSSPASEPAMRTGFYGFGFNVGTSSAARVELSHSGAFELGSGTNFVILP 378 Query 378 SEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQ 437 S D+AI+ALTNA P GVPETLTA+F DLVQ+G+VREDW LY +AFA + + GSLVGKQ Sbjct 379 SADVAIVALTNATPAGVPETLTAQFADLVQFGEVREDWYGLYHQAFADMEKPLGSLVGKQ 438 Query 438 SPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTL 497 PANPAP PL Y GVY ND+WGPA VT G L L +GP+ + + L HWDG+ FTF+ Sbjct 439 PPANPAPPAPLPSYAGVYNNDFWGPAEVTEAGGTLGLRVGPRGEVWPLKHWDGNVFTFSF 498 Query 498 STENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +EN+ PGS+SKATF G+ L LEY+D + G F R Sbjct 499 VSENSPPGSVSKATFDGNRLTLEYFDEEHNGVFFR 533 >gi|108801392|ref|YP_641589.1| beta-lactamase [Mycobacterium sp. MCS] gi|119870545|ref|YP_940497.1| beta-lactamase [Mycobacterium sp. KMS] gi|108771811|gb|ABG10533.1| beta-lactamase [Mycobacterium sp. MCS] gi|119696634|gb|ABL93707.1| beta-lactamase [Mycobacterium sp. KMS] Length=533 Score = 596 bits (1536), Expect = 3e-168, Method: Compositional matrix adjust. Identities = 315/515 (62%), Positives = 379/515 (74%), Gaps = 10/515 (1%) Query 24 GCGST----HQALGPPSGLP--DASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIP 77 GC S Q+ PP P D P +A+ +P +D AV ++DG+V EL+ +GIP Sbjct 23 GCDSAPTEEAQSTQPPPATPQSDVPPPLVAAVPLPDNAVDKAVGQLDGMVEELLAKSGIP 82 Query 78 GMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDN 137 GMAVA+VHGGKT+YAKGFGV DV G KVD DTVFQLAS+SK +GATVVAH V Sbjct 83 GMAVAVVHGGKTVYAKGFGVTDVKTGA----KVDPDTVFQLASMSKPLGATVVAHQVGRG 138 Query 138 VVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRL 197 + WDTP+VSKLPWFAL DP VT VT+ DLYSHRSGLPDHAGDLLEDLGYDRR +L+RL Sbjct 139 AIGWDTPIVSKLPWFALSDPAVTQMVTVGDLYSHRSGLPDHAGDLLEDLGYDRRAILERL 198 Query 198 KYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLA 257 + LPLAPFR SYAYTNFG+TAAAEAVA +AG+ WE LS+EVLYRPLGM STSSRF D+ Sbjct 199 RALPLAPFRDSYAYTNFGLTAAAEAVATSAGKPWETLSEEVLYRPLGMNSTSSRFADYEK 258 Query 258 RPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSP 317 RP+ AV H+ V R+E Y R+ DA+ PAGG SSS+ND+T WLAMVLADG G+++ P Sbjct 259 RPDRAVGHIHVDGRYEPLYVRNADAEGPAGGASSSVNDLTKWLAMVLADGKAGGQQLVEP 318 Query 318 EALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLP 377 +ALLP TPQ +S P R FYG+GFNVG +S+ R E SHSGAF LG+ NFV+LP Sbjct 319 DALLPAVTPQSVSSPASEPAMRTGFYGFGFNVGTSSAARVELSHSGAFELGSGTNFVILP 378 Query 378 SEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQ 437 S D+AI+ALTNA P GVPETLTA+F DLVQ+G+VREDW LY +AFA + + GSLVGKQ Sbjct 379 SADVAIVALTNATPAGVPETLTAQFADLVQFGEVREDWYGLYHQAFADMEKPLGSLVGKQ 438 Query 438 SPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTL 497 PANPAP PL Y GVY ND+WGPA VT G L L +GP+ + + L HWDG+ FTF+ Sbjct 439 PPANPAPPAPLPSYAGVYNNDFWGPAEVTEAGGTLGLRVGPRGEVWPLKHWDGNVFTFSF 498 Query 498 STENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +EN+ PGS+S+ATF G+ L LEY+D + G F R Sbjct 499 VSENSPPGSVSEATFDGNRLTLEYFDEEHNGVFFR 533 >gi|262200737|ref|YP_003271945.1| beta-lactamase [Gordonia bronchialis DSM 43247] gi|262084084|gb|ACY20052.1| beta-lactamase [Gordonia bronchialis DSM 43247] Length=551 Score = 582 bits (1500), Expect = 5e-164, Method: Compositional matrix adjust. Identities = 290/496 (59%), Positives = 363/496 (74%), Gaps = 9/496 (1%) Query 42 SPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVG 101 +PN + A +PA + DAV+++D LV +M++TGIPG+AVA+V G +T YAKGFGV DV Sbjct 59 NPNAQVASPLPADAVADAVSRLDDLVSSMMRDTGIPGLAVAVVAGAETKYAKGFGVADVT 118 Query 102 KGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTG 161 G +VDADTVF LAS+SKS+G+TV+A V++ + WD PV++ LP FAL DPYVT Sbjct 119 TGA----RVDADTVFPLASMSKSIGSTVIATQVSNRALGWDDPVITGLPGFALADPYVTR 174 Query 162 QVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAE 221 VT+AD+Y+HRSGLPDHAGD +EDLGY R +VL RL++LPL PFRI+Y YTNFGVTAAAE Sbjct 175 TVTVADMYAHRSGLPDHAGDKIEDLGYSRAEVLNRLRFLPLEPFRITYEYTNFGVTAAAE 234 Query 222 AVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRW-EARYQRDP 280 +VA + WE LS + +Y PLGM TSSRF DF AR N V HVKV D+W QR+P Sbjct 235 SVANRVRKDWETLSADAVYGPLGMSRTSSRFRDFAARENRVVGHVKVDDKWVTTPAQREP 294 Query 281 DAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARA 340 D QSPAGGVSSS+ND++HWLAM+L DG Y GR++ SPEALLP TPQ++S +P ARA Sbjct 295 DPQSPAGGVSSSVNDVSHWLAMLLGDGTYQGRQLISPEALLPAITPQIVSSPAAAPDARA 354 Query 341 SFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTA 400 FYGYGFNV VT GRT+ SHSGAF +GAA NF+VLPS D+AI+ L+NA P+G E LT Sbjct 355 GFYGYGFNVSVTEGGRTQVSHSGAFSMGAATNFLVLPSADVAIVVLSNAAPVGAVEALTG 414 Query 401 EFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYW 460 EF DLVQ+G +R DW LY +AFA ++ +GSLVGK PANPAP++PL+ Y G Y N + Sbjct 415 EFADLVQFGAIRHDWRTLYGQAFAEMSTPSGSLVGKPRPANPAPAQPLSVYAGTYDNPLY 474 Query 461 GPATVTYHDGQLRLSLGPKNQTF-DLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNL 519 GPA V DG+L L++GP + +LTHWD +TFTFT+ ENA G+ISK TF G + + Sbjct 475 GPAVVREQDGRLVLAMGPGGRAVRELTHWDANTFTFTMRDENAELGTISKVTFDGPRMTI 534 Query 520 EYYDADKL---GTFTR 532 EYY D G FTR Sbjct 535 EYYQDDDDPGGGVFTR 550 >gi|343925723|ref|ZP_08765238.1| putative penicillin-binding protein [Gordonia alkanivorans NBRC 16433] gi|343764074|dbj|GAA12164.1| putative penicillin-binding protein [Gordonia alkanivorans NBRC 16433] Length=563 Score = 562 bits (1449), Expect = 4e-158, Method: Compositional matrix adjust. Identities = 293/522 (57%), Positives = 370/522 (71%), Gaps = 12/522 (2%) Query 19 VADVNGCGSTHQALGPPSGLPDAS-----PNERSAIQIPAGRIDDAVAKVDGLVGELMQN 73 +A V C + G P P + PN A+ +P G +D AV ++DGL LM + Sbjct 45 IALVAACDTASSGTGNPPTEPSGASALVNPNAVDAMPLPDGAVDKAVGQLDGLAESLMSS 104 Query 74 TGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHA 133 TG+PG+AVA+V GG+T YAKGFGV+D+ G KVD +TVFQLASVSKSVG+TVV A Sbjct 105 TGLPGLAVAVVSGGETKYAKGFGVKDLTTG----QKVDPNTVFQLASVSKSVGSTVVGAA 160 Query 134 VTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQV 193 VTD V W P+V LPWFAL +PYVT VT+ D+YSHRSGLPDHAGD LED+GY + ++ Sbjct 161 VTDKTVAWGMPIVEGLPWFALAEPYVTRTVTVGDMYSHRSGLPDHAGDKLEDMGYSQTEI 220 Query 194 LQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFT 253 LQRL+++PL PFRISYAYTNFGVT EAVAA AG+ W LS +++Y PLGM STSSR+ Sbjct 221 LQRLRFMPLDPFRISYAYTNFGVTTGGEAVAAKAGKDWPTLSQDLIYGPLGMTSTSSRYA 280 Query 254 DFLARPNHAVNHVKVADRW-EARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGR 312 DF R + AV H+K+ +W + RDPDAQSPAGGVSS++NDM WL MVLA G +NG Sbjct 281 DFEKRADRAVGHIKIDGKWAKTDIPRDPDAQSPAGGVSSTVNDMAVWLKMVLAQGKHNGA 340 Query 313 RITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAAN 372 I +P+ALLP +PQ++S P SP RA FYG+GFNVGVT+ RT++SH+GAF GA + Sbjct 341 EIVAPDALLPAVSPQIVSNPPASPDDRAGFYGHGFNVGVTTDARTQFSHAGAFASGAGTS 400 Query 373 FVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGS 432 F +LPS D AI+ L+NA PIG + L AEFMDLVQ+G++R DW ALY KA+APL+ +G Sbjct 401 FSILPSADTAIVVLSNAAPIGAVDALAAEFMDLVQFGEIRSDWRALYAKAYAPLSVPSGD 460 Query 433 LVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKN-QTFDLTHWDGD 491 LVGKQ+PANPAP++PL +VG YAN +GPA V DG+L L +GP + +L HWD + Sbjct 461 LVGKQAPANPAPAQPLPTFVGTYANAVYGPAEVVERDGKLFLEMGPGGVRKHELAHWDRN 520 Query 492 TFTFTLSTENALPGSISKATFAGDTLNLEYYDADKL-GTFTR 532 FTFTL ENA GSIS+ TF G + +EYYD ++ G F R Sbjct 521 IFTFTLHDENAELGSISQVTFDGPKMTIEYYDDEESDGVFLR 562 >gi|229493944|ref|ZP_04387716.1| penicillin-binding protein 4 [Rhodococcus erythropolis SK121] gi|229319221|gb|EEN85070.1| penicillin-binding protein 4 [Rhodococcus erythropolis SK121] Length=537 Score = 559 bits (1440), Expect = 5e-157, Method: Compositional matrix adjust. Identities = 305/517 (59%), Positives = 372/517 (72%), Gaps = 9/517 (1%) Query 19 VADVNGCGS---THQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTG 75 VA + GC S T A GP + DASP + + IP G+IDDAV K+D L +LM ++G Sbjct 22 VALLAGCSSDSDTTSAPGPV--VSDASPGLDAGVPIPDGQIDDAVGKLDDLANDLMASSG 79 Query 76 IPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVT 135 +PGMAVA+VHGGKT+YAKGFGVR++GK VDADTVFQLASVSKSVGATVVAH V Sbjct 80 VPGMAVAVVHGGKTVYAKGFGVRELGKSA----TVDADTVFQLASVSKSVGATVVAHEVG 135 Query 136 DNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQ 195 V WDTPV+SKLP FAL DP+VT +TI+DLY+HRSGLPDHAGD LEDLGY+R QVL+ Sbjct 136 IGTVDWDTPVISKLPGFALADPWVTDHLTISDLYTHRSGLPDHAGDGLEDLGYNRAQVLE 195 Query 196 RLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDF 255 +L+ LPL PFRI+Y YTNFGVTA AEAVAAAAG WE LS +Y PLGM STSSRF D+ Sbjct 196 KLRQLPLNPFRITYEYTNFGVTAGAEAVAAAAGTDWETLSQNTIYGPLGMTSTSSRFADY 255 Query 256 LARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRIT 315 AR N V H+ +++ RD DAQSPAGGVSSS+NDM WL MVL+ G Y G+++ Sbjct 256 QARENRTVGHILEDGKYKVGPVRDADAQSPAGGVSSSVNDMAKWLDMVLSGGRYQGQQVV 315 Query 316 SPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVV 375 +AL+P P+++SRH R+ FYGYGFNV +++GR SHSGAF LGA NFV Sbjct 316 QTDALVPAVNPEIVSRHAQEIGERSGFYGYGFNVSDSAAGRVTASHSGAFLLGAGTNFVT 375 Query 376 LPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVG 435 +PS D+ I+ LTN P GV ETLTAEF DLVQ+G++ +W ALY+ +FA + G L G Sbjct 376 IPSADVGIVVLTNGTPTGVAETLTAEFADLVQFGKITREWRALYEASFASQADPEGELAG 435 Query 436 KQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTF 495 K PA+PAP+ P + G Y N YWGPA VT +G L L++GP T+ LTHWDG+TFTF Sbjct 436 KTPPASPAPAPPTDQLTGDYGNPYWGPALVTQQNGALTLTMGPAAATYPLTHWDGNTFTF 495 Query 496 TLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 LS ENA G++SKATF G++L LEY+D D LGTF R Sbjct 496 PLSGENAPAGTVSKATFDGNSLTLEYFDHDHLGTFIR 532 >gi|154245570|ref|YP_001416528.1| beta-lactamase [Xanthobacter autotrophicus Py2] gi|154159655|gb|ABS66871.1| beta-lactamase [Xanthobacter autotrophicus Py2] Length=533 Score = 547 bits (1410), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 289/501 (58%), Positives = 352/501 (71%), Gaps = 12/501 (2%) Query 40 DAS--PNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGV 97 DAS P + S + IP G+I+ AV KVD L +LM +GIPG+AVA+VH GKT++ KG+GV Sbjct 36 DASRPPPQTSGVPIPKGQIETAVGKVDALARDLMTRSGIPGLAVAVVHEGKTVFLKGYGV 95 Query 98 RDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDP 157 R VG+ +DADTVFQLAS+SKSVG++VVAH V V WDTPV LPWFAL D Sbjct 96 RKVGESAA----IDADTVFQLASLSKSVGSSVVAHEVGKGTVKWDTPVEDLLPWFALNDD 151 Query 158 YVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVT 217 +V+ VTIADLYSHRSGLPDHAGD LEDLGYDRRQVL+RLK LPLAPFR+SYAYTNFGVT Sbjct 152 WVSEHVTIADLYSHRSGLPDHAGDELEDLGYDRRQVLERLKKLPLAPFRVSYAYTNFGVT 211 Query 218 AAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKV-----ADRW 272 AAAEAVA A+G+ WE LS+EVLY+PLGM STSSRF+D++AR N AV HV+V + + Sbjct 212 AAAEAVATASGKDWETLSEEVLYKPLGMASTSSRFSDYMARSNRAVPHVRVGKIGESKTF 271 Query 273 EARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRH 332 A++QRDP AQSPAGGVSSS+ DM WL VL G Y GR+I +ALLP P++IS Sbjct 272 AAKFQRDPQAQSPAGGVSSSVRDMARWLGFVLGGGTYEGRQIVPEKALLPAMRPEMISSP 331 Query 333 PVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPI 392 + ARA FYGYGF V V+ +GR HSGAF LGA +V+LPSE L I+ LTNA P Sbjct 332 AYAADARAGFYGYGFAVNVSPAGRVMIDHSGAFILGAGTTYVLLPSEKLGIVVLTNAQPT 391 Query 393 GVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYV 452 GVPE L A FMDL Q+G V DW Y PL G+L GK +PA P P++PL YV Sbjct 392 GVPEALAASFMDLAQFGTVTRDWLTAYGPLIDPLYTPLGTLAGKSAPARPTPAKPLATYV 451 Query 453 GVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALP-GSISKAT 511 G YAN Y+G A V+ G+L L++GPK + F L HW GD F F E P GS+S+ T Sbjct 452 GTYANAYFGEARVSEDKGRLILTVGPKPRVFTLDHWSGDDFIFRPEGEETAPVGSVSQVT 511 Query 512 FAGDTLNLEYYDADKLGTFTR 532 F+ + +E+++ + LGTF R Sbjct 512 FSDRRMKVEFFNDNGLGTFER 532 >gi|54024183|ref|YP_118425.1| hypothetical protein nfa22140 [Nocardia farcinica IFM 10152] gi|54015691|dbj|BAD57061.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=545 Score = 546 bits (1407), Expect = 4e-153, Method: Compositional matrix adjust. Identities = 302/519 (59%), Positives = 354/519 (69%), Gaps = 7/519 (1%) Query 17 GDVADVNG--CGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNT 74 G AD +G +T A P+ + PNE + + IP G++D AV ++D + GELM T Sbjct 30 GACADDSGGDAATTSSAPRSPAATGELPPNEVAGVAIPDGQVDRAVGELDRIAGELMDAT 89 Query 75 GIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAV 134 IPGMAVA+VH GK +Y+KGFGVRDV G V DTVFQLAS+SK +GATVVA V Sbjct 90 KIPGMAVAVVHDGKVVYSKGFGVRDVTTG----QPVGPDTVFQLASLSKPIGATVVAREV 145 Query 135 TDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVL 194 V WDTPV P F L DPYV VT+ DLY+HRSGLPDHAGDLLEDLGYDR +L Sbjct 146 AAGRVAWDTPVRRLSPEFTLADPYVGDHVTVGDLYAHRSGLPDHAGDLLEDLGYDRAAIL 205 Query 195 QRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTD 254 RL+ LPLAPFR SYAYTNFG+TAAA AVA AAG WE LS +Y PLGM STSSR+ D Sbjct 206 ARLRQLPLAPFRDSYAYTNFGLTAAASAVAQAAGTDWETLSQREIYEPLGMTSTSSRYAD 265 Query 255 FLARPNHAVNHVKVADRWE-ARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRR 313 F+AR + AV HV V + A R PDAQSPAGGVSSS DMT WL M+L DG GR Sbjct 266 FVARGDRAVGHVLVDGAYRPADPPRRPDAQSPAGGVSSSARDMTRWLTMMLGDGSVEGRE 325 Query 314 ITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANF 373 I P ALLP +PQ++S P +P ARA FYG+GFNVG + +GR SHSGAF LGA F Sbjct 326 IVPPAALLPAVSPQMMSAPPANPDARAGFYGFGFNVGTSPAGRVVLSHSGAFNLGAGTAF 385 Query 374 VVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSL 433 ++PS + I+ LTNA P GVPETL AEF DLVQ+G+VREDW LY +AF L+ G L Sbjct 386 TMIPSAGVGIVTLTNAAPRGVPETLNAEFADLVQFGEVREDWRGLYTEAFDQLDAPKGDL 445 Query 434 VGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTF 493 VGK+ P PAP+RPL DY G YAN Y+GPATV +L ++LGP L HWDGDTF Sbjct 446 VGKEPPRAPAPARPLTDYAGTYANAYYGPATVAVRGDELTVTLGPAGTVVPLRHWDGDTF 505 Query 494 TFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 FT S E A PG++S+A F GD L LEYYD D +GTFTR Sbjct 506 AFTPSGEGADPGTVSQARFDGDRLTLEYYDQDGMGTFTR 544 >gi|226307733|ref|YP_002767693.1| penicillin-binding protein [Rhodococcus erythropolis PR4] gi|226186850|dbj|BAH34954.1| putative penicillin-binding protein [Rhodococcus erythropolis PR4] Length=537 Score = 545 bits (1404), Expect = 7e-153, Method: Compositional matrix adjust. Identities = 305/517 (59%), Positives = 369/517 (72%), Gaps = 9/517 (1%) Query 19 VADVNGCGS---THQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTG 75 VA + GC S T A GP + DASP + + IP G+IDDAV K+DGL +LM ++G Sbjct 22 VALLAGCSSDSDTTSAPGPV--VSDASPGLDAGVPIPDGQIDDAVGKLDGLANDLMASSG 79 Query 76 IPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVT 135 +PGMAVA+VHGGKT+YAKGFGVR++GK VDADTVFQLASVSKSVGATVVAH V Sbjct 80 VPGMAVAVVHGGKTVYAKGFGVRELGKSA----TVDADTVFQLASVSKSVGATVVAHEVG 135 Query 136 DNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQ 195 V WDTPV+SKLP FAL DP+VT +TI+DLY+HRSGLPDHAGD LEDLGY+R QVL+ Sbjct 136 IGTVDWDTPVISKLPGFALGDPWVTDHLTISDLYTHRSGLPDHAGDGLEDLGYNRAQVLE 195 Query 196 RLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDF 255 +L+ LPL PFRI+Y YTNFGVTA AEAVAAAAG WE LS +Y PLGM STSSRF D+ Sbjct 196 KLRQLPLNPFRITYEYTNFGVTAGAEAVAAAAGTDWETLSQNTIYGPLGMTSTSSRFADY 255 Query 256 LARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRIT 315 AR N V H+ +++ RD DAQSPAGGVSSS NDM WL MVL+ G Y G+++ Sbjct 256 QARENRTVGHILEDGKYKVGPVRDADAQSPAGGVSSSANDMAKWLDMVLSGGQYQGQQVV 315 Query 316 SPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVV 375 +AL+P P+++SRH R+ FYGYGFNV +++GR SHSGAF +GA NFV Sbjct 316 QTDALVPAVNPEIVSRHAQEIGERSGFYGYGFNVSDSAAGRVTASHSGAFLVGAGTNFVT 375 Query 376 LPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVG 435 +PS D+ I+ LTN P GV ETLTAEF DLVQ+G++ +W LY+ AFA + G L G Sbjct 376 IPSADVGIVVLTNGTPTGVAETLTAEFADLVQFGKITREWRPLYEAAFASQADPEGELAG 435 Query 436 KQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTF 495 K PA PAP+ P N G Y N YWGPA VT + L L++GP T+ LTHWDG+TFTF Sbjct 436 KTPPATPAPAPPTNQLTGDYGNPYWGPALVTQQNAALTLTMGPAAVTYPLTHWDGNTFTF 495 Query 496 TLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 LS ENA G++SKATF G++L LEY+D D LGTF R Sbjct 496 PLSGENAPAGTVSKATFDGNSLTLEYFDHDHLGTFIR 532 >gi|194289848|ref|YP_002005755.1| beta-lactamase [Cupriavidus taiwanensis LMG 19424] gi|193223683|emb|CAQ69690.1| putative beta-lactamase [Cupriavidus taiwanensis LMG 19424] Length=559 Score = 530 bits (1364), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 277/480 (58%), Positives = 336/480 (70%), Gaps = 5/480 (1%) Query 53 AGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDA 112 A +I A+A+VD L +LM ++G+PGMAVA+V G +T+YA+GFG R V VDA Sbjct 85 AAQITRAIAQVDQLAADLMASSGVPGMAVAVVRGNQTVYARGFGRRLVTD----PAPVDA 140 Query 113 DTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHR 172 DTVFQLASVSKS+GATVVA V + WDTPV + LPWF L D V+ VT+ DLY+HR Sbjct 141 DTVFQLASVSKSIGATVVARQVGRGSIGWDTPVRTHLPWFTLADAEVSADVTVGDLYAHR 200 Query 173 SGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWE 232 SGLPDHAGD LED+GYDR+QVL RL++LPL PFR YAYTNFG+TAAAEAVA AAG W Sbjct 201 SGLPDHAGDRLEDMGYDRQQVLTRLRFLPLHPFRGVYAYTNFGMTAAAEAVAVAAGTDWA 260 Query 233 DLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSS 292 LS++ LY+PLGM TSSR+ D+ AR N AV HV+V W R PDAQSPAGGVS+S Sbjct 261 TLSEQALYQPLGMTRTSSRYADYAARDNRAVGHVRVNGNWVQGASRMPDAQSPAGGVSAS 320 Query 293 LNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVT 352 +NDM WLAM+LA G + G+R+ AL P +PQ+ S P + R A FYGYGFNVG T Sbjct 321 VNDMAKWLAMLLARGEFAGQRVVDAAALAPAVSPQMQSNPPANGRP-AGFYGYGFNVGTT 379 Query 353 SSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVR 412 G T +HSGAF +G A +FV +P DLAI+ LTNA PIGVPETL A+F DL QYG +R Sbjct 380 ELGLTSLNHSGAFAMGVATSFVAVPELDLAIVTLTNAQPIGVPETLNAQFFDLAQYGAIR 439 Query 413 EDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQL 472 DW +Y A APL E G LVG+ PANP P+R L+ Y GVY NDY+GP V G L Sbjct 440 RDWGKIYGDALAPLLEPEGRLVGQPRPANPLPARALSAYTGVYRNDYYGPLQVADQGGTL 499 Query 473 RLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 ++LG L+HWDGD FTFTL ENA+PG+IS+A F+ D + LE+YD + LG F R Sbjct 500 VMTLGATPLVLPLSHWDGDIFTFTLVNENAMPGTISQAAFSSDRVWLEFYDHEGLGMFVR 559 >gi|113868104|ref|YP_726593.1| Beta-lactamase class C [Ralstonia eutropha H16] gi|113526880|emb|CAJ93225.1| Beta-lactamase class C [Ralstonia eutropha H16] Length=516 Score = 523 bits (1347), Expect = 3e-146, Method: Compositional matrix adjust. Identities = 275/478 (58%), Positives = 335/478 (71%), Gaps = 5/478 (1%) Query 55 RIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADT 114 +I A+A++D L +LM ++G+PGMAVA+V G +T+YAKGFG R V VDADT Sbjct 44 QITQAIAQIDKLAADLMASSGVPGMAVAVVRGNQTVYAKGFGRRLVTD----PAPVDADT 99 Query 115 VFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSG 174 VFQLASVSK +GATVVA V ++WDTPV + LPWFAL + VT VTI DLY+HRSG Sbjct 100 VFQLASVSKPIGATVVARQVGRGGISWDTPVRAHLPWFALAEAEVTEAVTIGDLYAHRSG 159 Query 175 LPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDL 234 LPDHAGD LED+G+DR+QVL RL+YLPL PFR YAYTNFG+TAAAEAVA AAG W L Sbjct 160 LPDHAGDRLEDMGFDRQQVLTRLRYLPLHPFRAVYAYTNFGMTAAAEAVATAAGIDWATL 219 Query 235 SDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLN 294 S++ +Y+PLGM TSSR+ DF AR N A+ HV++ W PDAQSPAGGVSSS+N Sbjct 220 SEQAIYQPLGMARTSSRYADFAARDNRALGHVRINGAWVQGMGTMPDAQSPAGGVSSSVN 279 Query 295 DMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSS 354 D+ WLAM+LA G + G+RI AL P + Q+ S PVS R A +YGYGFNVG T Sbjct 280 DIAKWLAMLLAKGEFAGQRIVDAAALAPALSQQMQSSPPVSGRP-AGYYGYGFNVGTTEL 338 Query 355 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVRED 414 G Y+HSGAF +GAA N +PS +LAI+ LTN PIGVPETL A+F DLVQYG +R D Sbjct 339 GLASYNHSGAFAVGAATNLTAVPSLNLAIVTLTNGYPIGVPETLNAQFFDLVQYGAIRRD 398 Query 415 WAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRL 474 W +Y A APL G LVG+ PANP P+R L+ Y G+Y NDY+GP V G L + Sbjct 399 WGKIYGDALAPLLAPEGRLVGQAPPANPLPARALSAYTGIYQNDYYGPLQVADQGGTLVM 458 Query 475 SLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +LG T L+HWDGD FTFTL+ ENA PG+IS+A F+ D + LEYYD + LG F R Sbjct 459 TLGATPLTLPLSHWDGDVFTFTLNNENATPGTISQAAFSSDRVWLEYYDHEGLGMFVR 516 >gi|339326183|ref|YP_004685876.1| beta-lactamase class C [Cupriavidus necator N-1] gi|338166340|gb|AEI77395.1| beta-lactamase class C [Cupriavidus necator N-1] Length=516 Score = 521 bits (1342), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 278/478 (59%), Positives = 333/478 (70%), Gaps = 5/478 (1%) Query 55 RIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADT 114 +I A+A++D L +LM ++ +PGMAVA+V G +T+YAKGFG R V VDADT Sbjct 44 QITQAIAQLDKLAADLMASSRVPGMAVAVVRGNQTVYAKGFGRRLVTD----PAPVDADT 99 Query 115 VFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSG 174 VFQLASVSKSVGATVVA V + WDTPV + LPWFAL D VT VTI DLY+HRSG Sbjct 100 VFQLASVSKSVGATVVARQVGRGGIGWDTPVRAHLPWFALSDAEVTQGVTIGDLYAHRSG 159 Query 175 LPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDL 234 LPDH GDLLED+GYDRRQVL RL+YLPL PF YAYTNFG+TAAAEAVA AAG W L Sbjct 160 LPDHGGDLLEDMGYDRRQVLTRLRYLPLHPFHAVYAYTNFGLTAAAEAVATAAGIDWATL 219 Query 235 SDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLN 294 S++ +Y+PLGM TSSR+ DF AR N A+ HV+V W R PDAQSPAGGVS+S+N Sbjct 220 SEQAIYQPLGMTRTSSRYADFAARDNRALGHVRVNGNWVQGAGRMPDAQSPAGGVSASVN 279 Query 295 DMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSS 354 DM WLAM+LA G + G+R+ AL P + Q+ S PV R A +YGYGFNVG T Sbjct 280 DMAKWLAMLLAKGEFAGQRVVDAAALTPALSQQMQSSPPVDGRP-AGYYGYGFNVGTTEL 338 Query 355 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVRED 414 G T Y+HSGAF GAA NF LP+ +LAI+ LTNA PIGVPETL+A+F DLVQYG +R D Sbjct 339 GLTSYNHSGAFVAGAATNFTALPALNLAIVTLTNAQPIGVPETLSAQFFDLVQYGAIRRD 398 Query 415 WAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRL 474 W +Y AFAPL G LVG+ PA+P P+R L+ Y G Y NDY+GP V G L + Sbjct 399 WGKIYGDAFAPLLAPEGRLVGQPRPASPLPARALSAYTGTYQNDYYGPLQVADQGGTLVM 458 Query 475 SLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR 532 +LG L+HWDGD FTFTL ENA PG+IS+A F+ D + LEYY+ + LG R Sbjct 459 TLGATPLVLPLSHWDGDVFTFTLENENATPGTISQAAFSSDRVWLEYYEHEGLGMLVR 516 >gi|75674850|ref|YP_317271.1| beta-lactamase [Nitrobacter winogradskyi Nb-255] gi|74419720|gb|ABA03919.1| beta-lactamase [Nitrobacter winogradskyi Nb-255] Length=531 Score = 507 bits (1305), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 273/502 (55%), Positives = 348/502 (70%), Gaps = 10/502 (1%) Query 37 GLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFG 96 G + SP + S + I G+ID+AVA +D + +M+ TGIPGMAVA+V GK YAKGFG Sbjct 33 GFAETSPPQTSGVPIADGQIDEAVAGLDAIATGVMKKTGIPGMAVAVVRDGKIAYAKGFG 92 Query 97 VRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRD 156 VR VG+ + +DA+TVFQ+AS+SKS+ ATVVA V +VV W+TPV + LPWF L D Sbjct 93 VRKVGE----NQPIDANTVFQIASLSKSIAATVVARQVGADVVKWNTPVQAHLPWFRLMD 148 Query 157 PYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGV 216 P+VT VTIADL+SHRSGLPDHAGD LEDLGY RR VL+RL+ LPL FR YAYTNFG+ Sbjct 149 PWVTQHVTIADLFSHRSGLPDHAGDDLEDLGYGRRAVLERLRLLPLHGFRDVYAYTNFGL 208 Query 217 TAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARY 276 TAAAEAVAAA+G+ WE LS+EVLY+PLGM +TSSRF DF + N A+ HV+ D ++ +Y Sbjct 209 TAAAEAVAAASGKDWESLSEEVLYKPLGMSATSSRFADFEKQANRAIGHVRGGDGFQPKY 268 Query 277 QRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSP 336 QR PDAQSPAGGVSSS ND+ WLA+VL +G + GR++ +ALLP T +V+S H S Sbjct 269 QRRPDAQSPAGGVSSSANDLARWLALVLRNGEFEGRQVIPADALLPAMTAEVVSIHSPSA 328 Query 337 RARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPE 396 ARAS YGYGF VGVT +GRT SHSGAF LGA ++ ++PS + I+ LTNA P+G E Sbjct 329 DARASLYGYGFGVGVTPAGRTMISHSGAFALGAGTHYTIIPSAGIGIVVLTNAEPVGAAE 388 Query 397 TLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYA 456 + A FMDLVQ+G++ DW A Y A L AG LVGK PA PAP+ YVG Y Sbjct 389 AVGASFMDLVQFGKITRDWLAAYSGVMAQLTAPAGDLVGKSPPAKPAPAASSTSYVGRYG 448 Query 457 NDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATF--AG 514 + Y+G A + +G + L +G ++++ LTHWDGD F+ S+EN GS+S TF G Sbjct 449 SPYFGDAEIVDANGHMELKIGRLSRSYTLTHWDGDVFSIKPSSENQTDGSVSSVTFKRTG 508 Query 515 D----TLNLEYYDADKLGTFTR 532 D L +E+ + + LG F R Sbjct 509 DEPASELTIEFLNDNGLGQFMR 530 >gi|220924478|ref|YP_002499780.1| beta-lactamase [Methylobacterium nodulans ORS 2060] gi|219949085|gb|ACL59477.1| beta-lactamase [Methylobacterium nodulans ORS 2060] Length=533 Score = 504 bits (1297), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 267/505 (53%), Positives = 346/505 (69%), Gaps = 10/505 (1%) Query 34 PPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAK 93 P L + SP + + I I G+ID A+A +D + ++M+ +G+PGMAVA+V GKT+YAK Sbjct 32 PTPSLAETSPPQTAGIPISNGQIDKAIASLDAIASDVMKRSGVPGMAVAVVRDGKTVYAK 91 Query 94 GFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFA 153 GFGVR +G+ +DADTVFQ+AS+SKS+ A+VVAH V + WDTP+V+ LPWF Sbjct 92 GFGVRKIGE----SQPIDADTVFQIASLSKSLAASVVAHEVGLGTIKWDTPLVAHLPWFR 147 Query 154 LRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTN 213 L DP++T VTIAD++SHRSGLP+HAGD LED GYDRR VL+RL+ LPL FR +YAYTN Sbjct 148 LGDPWITQHVTIADMFSHRSGLPEHAGDDLEDFGYDRRTVLERLRLLPLRSFRDTYAYTN 207 Query 214 FGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWE 273 FG+TAAAEAVAAA+G+ WE LS++VLY+PLGM +TSSRF DF + N A HVKV D + Sbjct 208 FGLTAAAEAVAAASGKDWESLSEDVLYKPLGMTATSSRFADFAKQSNRAFGHVKVGDAFL 267 Query 274 ARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHP 333 +YQR PDAQSPAGGVSSS ND+ WLA++L +G + GR+I +ALLP T + IS H Sbjct 268 PKYQRLPDAQSPAGGVSSSANDLARWLALMLQNGKFEGRQIIPADALLPAVTAEAISTHS 327 Query 334 VSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIG 393 + AR SFYGYGF VG+T +GRT SHSGAF LGA ++ ++PS + I+ LTNAGP G Sbjct 328 FAVDARPSFYGYGFGVGITPAGRTIVSHSGAFALGAGTHYAMIPSAGVGIVVLTNAGPGG 387 Query 394 VPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVG 453 E L A FMDLVQ+ V DW A Y+ A + L G LVGK P PAP+ L+ Y+G Sbjct 388 AAEALGASFMDLVQFSMVTRDWLAAYRAAMSELLAPTGDLVGKSPPTTPAPAAKLSSYIG 447 Query 454 VYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFA 513 YAN Y+G A + +G L L +G +++ LTHWDGD F + S+EN GS+S F Sbjct 448 SYANPYFGNAEIVEANGHLELRIGLSGKSYMLTHWDGDMFLVSPSSENQADGSLSSIAFK 507 Query 514 ------GDTLNLEYYDADKLGTFTR 532 + +EY + + LG F R Sbjct 508 RTGNEPAREVTIEYLNGNGLGLFLR 532 >gi|258654767|ref|YP_003203923.1| beta-lactamase [Nakamurella multipartita DSM 44233] gi|258557992|gb|ACV80934.1| beta-lactamase [Nakamurella multipartita DSM 44233] Length=485 Score = 491 bits (1264), Expect = 1e-136, Method: Compositional matrix adjust. Identities = 263/487 (55%), Positives = 326/487 (67%), Gaps = 14/487 (2%) Query 56 IDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTV 115 I A+ K+DGL + + T IPGMAVA+VH G+ ++AKG+GVR+VG+ VDA+TV Sbjct 3 IGSAIRKIDGLAASMQEQTNIPGMAVAVVHDGQIVFAKGYGVREVGQ----PEPVDANTV 58 Query 116 FQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGL 175 FQLAS+SK +GATV+A V V WDTP+++ LP FAL DPYVT VTIAD+YSHRSGL Sbjct 59 FQLASLSKPIGATVIAQEVGKGTVAWDTPLITHLPEFALADPYVTQNVTIADMYSHRSGL 118 Query 176 PDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLS 235 PDHAGDLLEDLGYDR VL +LKY PL PFR Y YTNFG+TA AE+VA A G WE LS Sbjct 119 PDHAGDLLEDLGYDRAYVLSKLKYEPLEPFRAIYHYTNFGITAGAESVARATGVDWETLS 178 Query 236 DEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLND 295 + +Y PLGM +TSS F DF A P+ AV HV V ++A+Y R PDA+SPAGGVSSS+ D Sbjct 179 ERDIYGPLGMSNTSSTFADFEANPDRAVGHVLVDGEYQAKYVRQPDAESPAGGVSSSVTD 238 Query 296 MTHWLAMVLADGVY-NGRRITSPEALLPVYTPQVISRH----PVSPRARASFYGYGFNVG 350 + WLAMVL +G +G ++ P AL TP + S P S RA FYGYGFNVG Sbjct 239 VATWLAMVLNEGTTADGTQLVDPAALNAALTPHMRSVEGSLIPPSITGRAGFYGYGFNVG 298 Query 351 VTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQ 410 ++GR HSGAFGLGA F+ +P +L I+ LTNA PIG E L+ EF DL ++G Sbjct 299 NDATGRVRIGHSGAFGLGAGTTFLGIPDLNLGIVVLTNAAPIGAAEALSQEFADLAEFGS 358 Query 411 VREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDG 470 ++ DW +Y AFA ++ GSL G+ +PANPAP+ + YVG Y NDY GPATV+ G Sbjct 359 IQHDWRPIYAGAFAAGSDPVGSLAGQSAPANPAPAAANSAYVGTYQNDYVGPATVSESGG 418 Query 471 QLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATF-----AGDTLNLEYYDAD 525 L L+LGP NQ F L HWDG FT + ENA GSIS TF T+ +E+Y+ + Sbjct 419 GLVLTLGPDNQQFPLAHWDGQVFTMVPTGENAPDGSISAVTFETTGETASTMTIEFYNKE 478 Query 526 KLGTFTR 532 LG F R Sbjct 479 GLGVFRR 485 >gi|338996917|ref|ZP_08635623.1| beta-lactamase [Halomonas sp. TD01] gi|338766200|gb|EGP21126.1| beta-lactamase [Halomonas sp. TD01] Length=540 Score = 478 bits (1229), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 259/507 (52%), Positives = 328/507 (65%), Gaps = 12/507 (2%) Query 34 PPSGLPD--ASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLY 91 P LPD SP + + +P RID+AVA +D LV ++++ TG+PG+AVA+VHG +TL Sbjct 37 PTIALPDPAISPARVNLLPVPQTRIDEAVASLDELVQDMLERTGVPGLAVAVVHGEETLL 96 Query 92 AKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPW 151 +G+G+R G + +VDADTVF LAS+SKSVGATVVA VTD +V+WD PV + LPW Sbjct 97 MRGWGLR----AEGAEEQVDADTVFMLASLSKSVGATVVATQVTDGIVSWDDPVRNHLPW 152 Query 152 FALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAY 211 F L DP+V+ VTI DLY+HRSGLPDHAGD LED+GYDRR VL+RL LP+ FR YAY Sbjct 153 FDLGDPWVSNHVTIGDLYAHRSGLPDHAGDDLEDIGYDRRAVLERLAQLPMGQFRADYAY 212 Query 212 TNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADR 271 TNFG+TAAAEAVA A G+ W LS+E LY PLGM TSSR +D++AR N A +HV A+ Sbjct 213 TNFGLTAAAEAVATATGKDWSTLSEEALYGPLGMEVTSSRHSDYMARDNRAASHVPDANG 272 Query 272 WEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISR 331 + R PDAQSPAGGVSSS DM W+ +VL+ G + G+++ +PEAL+P +P IS Sbjct 273 FRVADLRQPDAQSPAGGVSSSARDMAKWMKLVLSTGRFEGQQLIAPEALVPALSPHAISG 332 Query 332 HPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGP 391 HP RA YGYGF VGV +GR SHSGAF GAA ++ +LP L II LTNA P Sbjct 333 HPSEAADRAGTYGYGFGVGVRPTGRVVLSHSGAFAFGAATSYSMLPDLGLGIIVLTNASP 392 Query 392 IGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDY 451 G+PE LTA F+D ++G + DW A Y APL+ G L+G PA P +RP Y Sbjct 393 TGLPEALTASFLDRAEFGVEQRDWLAAYGPRIAPLSAPVGDLLGVTPPAEPTEARPAEAY 452 Query 452 VGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKAT 511 G+Y N Y+G A V L L +GP Q L HWDGD F TEN GS+S+ Sbjct 453 TGIYDNAYFGAAEVRETADGLVLEVGPAPQRLRLIHWDGDRFVAFPVTENQPEGSVSQVE 512 Query 512 FA------GDTLNLEYYDADKLGTFTR 532 F +T+ +E+ + LG F R Sbjct 513 FTMGADGKAETITVEHLNEAGLGEFHR 539 >gi|239820768|ref|YP_002947953.1| beta-lactamase [Variovorax paradoxus S110] gi|239805621|gb|ACS22687.1| beta-lactamase [Variovorax paradoxus S110] Length=536 Score = 470 bits (1209), Expect = 3e-130, Method: Compositional matrix adjust. Identities = 259/500 (52%), Positives = 324/500 (65%), Gaps = 12/500 (2%) Query 41 ASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDV 100 ASP+E A+ IP +ID AVA++D L ++M+ + IPGMAVA+V G+T+YAKGFGVR V Sbjct 37 ASPSETYAVAIPPAQIDAAVARLDQLAADIMRRSSIPGMAVAVVKDGRTVYAKGFGVRTV 96 Query 101 GKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVT 160 G VDADTVFQLAS+SKSVGATVVA V V++WDTPV + LP F L D ++T Sbjct 97 GA----PEPVDADTVFQLASLSKSVGATVVAGLVGRQVLSWDTPVATHLPGFRLSDEWIT 152 Query 161 GQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAA 220 QVT+ D ++HRSGL H GD LEDLGY R+ +L RL+Y+PL FR YAYTNFG+TA A Sbjct 153 QQVTMGDFFAHRSGLSAHVGDQLEDLGYGRQDMLDRLRYVPLDGFRTRYAYTNFGLTAGA 212 Query 221 EAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDP 280 EA A AAG W LS+ LY+PLGM STSSRF DF+ R N A HVK ++A+YQRDP Sbjct 213 EAAARAAGLDWATLSERTLYQPLGMASTSSRFADFMQRGNRASPHVKTEAGYQAQYQRDP 272 Query 281 DAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARA 340 DAQSPAGGVS+S NDM W++MVL G + GR + EALLP + Q++S +P RA Sbjct 273 DAQSPAGGVSASANDMARWMSMVLQQGSFQGRPVVEAEALLPATSAQIVSSPSRNPNERA 332 Query 341 SFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTA 400 FYGYGFNVG + SGR + SHSGAF LGA F ++PS + I+ LTNA P+G E + A Sbjct 333 GFYGYGFNVGTSPSGRVKLSHSGAFLLGAGTAFSMIPSAGVGIVTLTNAAPVGAAEAMNA 392 Query 401 EFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYW 460 F DLV++G + DW Y L G+L G+ PA P N Y G+YAN Y+ Sbjct 393 AFDDLVEFGALTRDWYEAYAPLMQGLYAPEGTLAGQPPPAQPVAPLGSNAYTGIYANSYY 452 Query 461 GPATVTYHDGQLRLSLGPKN-QTFDLTHWDGDTFTFTLSTENALPGSISKATF------A 513 G A V L L +GP + F L HW G+TF LS E+A PGSIS+ F Sbjct 453 GNAVVETAGSGLVLKMGPGGARRFALRHWSGNTFVIDLSGESATPGSISRIDFRPGVSGL 512 Query 514 GDTLNLEYYDADKL-GTFTR 532 D++ +E+Y D G FTR Sbjct 513 SDSVQMEFYAEDTTHGVFTR 532 >gi|118591784|ref|ZP_01549180.1| beta-lactamase [Stappia aggregata IAM 12614] gi|118435777|gb|EAV42422.1| beta-lactamase [Stappia aggregata IAM 12614] Length=525 Score = 469 bits (1208), Expect = 4e-130, Method: Compositional matrix adjust. Identities = 246/473 (53%), Positives = 315/473 (67%), Gaps = 4/473 (0%) Query 40 DASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRD 99 + SP + ++ +I A+A++D +V ++++ + IPG+AVA VH G T+YAKGFGVR Sbjct 30 ELSPAQTPGVEASPEQIAKAIAEIDAIVADVLERSNIPGLAVAAVHRGDTVYAKGFGVRR 89 Query 100 VGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYV 159 +G G P + DTVFQLAS+SK VG+TVVA V+ VVTWD+ + LPWF L DP Sbjct 90 LG-GSDP---ITPDTVFQLASLSKPVGSTVVARQVSKGVVTWDSRMRDLLPWFELSDPDR 145 Query 160 TGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAA 219 T ++TI DLYSHRSGLPDHAGD LEDLGY R+++LQRL+ LPLAPFRISYAYTNFG+TAA Sbjct 146 TEKLTIGDLYSHRSGLPDHAGDDLEDLGYGRKEILQRLRLLPLAPFRISYAYTNFGLTAA 205 Query 220 AEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRD 279 AEAVA A+G W LS+E LY+PLGM STSSRF D++A N A+ H + D + +QRD Sbjct 206 AEAVAEASGTDWSSLSEEALYQPLGMTSTSSRFADYMAAANRAIPHSRDGDGFAPLFQRD 265 Query 280 PDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRAR 339 PDAQSPAGGVSS++ND+ WL M+LA+G + G ++ +PEALLP +PQ S P SP AR Sbjct 266 PDAQSPAGGVSSTVNDLAIWLKMLLANGEHAGTQVIAPEALLPAISPQSFSDRPHSPDAR 325 Query 340 ASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLT 399 + FYGYGFNVG SGR HSGAF LGA F ++PS DL I+ LTNA P+G E + Sbjct 326 SGFYGYGFNVGTDPSGRVRIGHSGAFLLGAGTCFAMIPSLDLGIVVLTNAAPVGAAEAIA 385 Query 400 AEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDY 459 A F DL Q G + DW Y F GS VG+ P + AP+ P + G Y+N Y Sbjct 386 ASFTDLAQLGYITRDWYDGYSSRFEGFYTKLGSTVGQDRPTDAAPTPPQDRLTGTYSNPY 445 Query 460 WGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATF 512 +G V ++ L++GPK F L W+G F ++TENA GS S F Sbjct 446 FGKVEVKAEGEKMVLTIGPKQMLFPLQPWNGPVMVFDVTTENAPAGSRSTIVF 498 >gi|328883567|emb|CCA56806.1| Beta-lactamase [Streptomyces venezuelae ATCC 10712] Length=504 Score = 455 bits (1170), Expect = 9e-126, Method: Compositional matrix adjust. Identities = 245/485 (51%), Positives = 325/485 (68%), Gaps = 20/485 (4%) Query 56 IDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTV 115 +D AV ++DG V ELM+ TG+PG++VA+V+ GK L+ +G+GVR+VGK +VDADTV Sbjct 31 VDRAVDRLDGSVAELMRKTGVPGVSVAVVYKGKVLHIQGYGVREVGKSA----RVDADTV 86 Query 116 FQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGL 175 FQLASVSK + +T+V+ AV V W PV +LP F L+DP+VT +T ADL+SHRSGL Sbjct 87 FQLASVSKPIASTIVSGAV--GVEGWQKPVNPELPDFRLKDPWVTSHMTAADLFSHRSGL 144 Query 176 PDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLS 235 PDHAGDLLEDLGYD+ +L L+Y PLAPFR+SYAYTNFG+T AAEAVAA G WE L+ Sbjct 145 PDHAGDLLEDLGYDQDYILSHLRYEPLAPFRVSYAYTNFGLTGAAEAVAAEKGVPWEKLA 204 Query 236 DEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVAD-RWEARYQRDPDAQSPAGGVSSSLN 294 ++ LY+P GM TSSRF DF++ P+ A HVK D W+A++ RDPDAQSPAGGVSSS Sbjct 205 EDTLYKPAGMNDTSSRFEDFVSNPDRAHGHVKQPDGTWKAQFVRDPDAQSPAGGVSSSAR 264 Query 295 DMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSS 354 DM WL + LA G +G+RI + +AL+ + P+ +S +P AR FYG G+NV Sbjct 265 DMARWLRLQLAGGELDGKRIVAEDALVLTHHPESVSGPAQAPAARTGFYGLGWNVSYDDE 324 Query 355 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVRED 414 GR SH+GAF GA N +LP E L I+ LTN P+GV +T+ +F D Q G+ D Sbjct 325 GRLRLSHTGAFAEGAHTNVTMLPGEQLGIVVLTNGAPVGVADTVALDFFDTAQDGKPSRD 384 Query 415 WA----ALY-KKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHD 469 W ALY ++A A L+ + + PA+ P++ + Y G + +DY+G A V + Sbjct 385 WLPIVDALYEQEADADLSPTDYA----KPPADAEPAKASDAYTGTFTSDYYGRAQVVEEN 440 Query 470 GQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFA--GDTLNLEYYDADKL 527 G L L LGPK QT+ LTH+DGDTF+F ENA+ ++ TF+ G +L +EY D + L Sbjct 441 GGLVLRLGPKPQTYKLTHYDGDTFSFPTRGENAV--GLTGVTFSPDGTSLRVEYLDQEGL 498 Query 528 GTFTR 532 GTFTR Sbjct 499 GTFTR 503 >gi|344341418|ref|ZP_08772338.1| beta-lactamase [Thiocapsa marina 5811] gi|343798753|gb|EGV16707.1| beta-lactamase [Thiocapsa marina 5811] Length=533 Score = 454 bits (1167), Expect = 2e-125, Method: Compositional matrix adjust. Identities = 252/501 (51%), Positives = 332/501 (67%), Gaps = 19/501 (3%) Query 43 PNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGK 102 P+ S + IP GR++ AV ++D + ++ TG+PGMA+A+VH + +Y KGFG+R + Sbjct 41 PSAFSDVMIPEGRVEAAVGQLDAMAEAALETTGVPGMAIAVVHRDRVVYLKGFGLRSLDG 100 Query 103 GGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNV-----VTWDTPVVSKLPWFALRDP 157 + +VD +TVFQLAS+SK V ATVVA A+ + WD P+V LP FAL DP Sbjct 101 ----EARVDDETVFQLASLSKPVAATVVAAAIDRTHGERAGLAWDDPIVRHLPDFALNDP 156 Query 158 YVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVT 217 +T +VTIADL++HRSGLPDHAGDLLE +GY R ++L RL++ PLAPFR SYAYTNFG+T Sbjct 157 AITSRVTIADLFAHRSGLPDHAGDLLESIGYGRAEILSRLRFYPLAPFRASYAYTNFGLT 216 Query 218 AAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQ 277 AAAEAVA A G SWE LS E+LY PLGM STSSRF DF++ PNHA+ HV+ W + Sbjct 217 AAAEAVARAEGTSWERLSQELLYSPLGMTSTSSRFADFISAPNHAIGHVRRDGVWVVTPE 276 Query 278 -RDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSP 336 R+PDAQSPAGGVSSS +DM WL +VL +G+ G+ + +AL ++ P ++S P Sbjct 277 VREPDAQSPAGGVSSSASDMAQWLRLVLGEGMLEGKPVIGAQALARIHAPNLMSSPLHGP 336 Query 337 RARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPE 396 +R SFYG G V V S+GR +SHSGAF LGA+ +LPSE L I+ LTN P+G PE Sbjct 337 SSRPSFYGLGLGVSVDSAGRVRWSHSGAFLLGASTTLAMLPSESLGIVILTNGQPVGAPE 396 Query 397 TLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYA 456 + A F++LV+ G++R DW AL+ A A L A + ++P+ PAP+RPL+ YVG YA Sbjct 397 GVAAGFLELVETGEIRHDWPALFGGAIARL--YAETTAFAETPSAPAPARPLDVYVGRYA 454 Query 457 NDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGD- 515 ND +GPA V D L L LGP ++H+DGD FTF E+AL +S A F D Sbjct 455 NDLYGPAVVEATDAGLVLRLGPSPIALPMSHFDGDAFTFRPIGEDAL--GVSGAVFGFDD 512 Query 516 ----TLNLEYYDADKLGTFTR 532 +L +EY D + LGTF R Sbjct 513 ERAASLQIEYLDEEGLGTFRR 533 >gi|333917323|ref|YP_004491055.1| beta-lactamase [Delftia sp. Cs1-4] gi|333747523|gb|AEF92700.1| beta-lactamase [Delftia sp. Cs1-4] Length=519 Score = 446 bits (1146), Expect = 7e-123, Method: Compositional matrix adjust. Identities = 242/471 (52%), Positives = 319/471 (68%), Gaps = 11/471 (2%) Query 55 RIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADT 114 R+ A+ ++DG V M+ TG+PG+AVA+VH G+ +YA+G GVR +G VDADT Sbjct 41 RVKRALDQLDGQVRAQMRRTGVPGVAVAVVHEGRLVYAQGMGVRRLGS----SLAVDADT 96 Query 115 VFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSG 174 VFQLASVSKSVGATVVA V V+WDT V LPW+ L D ++T+ D+Y+HRSG Sbjct 97 VFQLASVSKSVGATVVAQQVGQRRVSWDTRVQQGLPWWTLEDADAAQRITVGDMYAHRSG 156 Query 175 LPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDL 234 LP AGD LE+LGY +RQ+L+RL+YLPL P YAY+NFG+T AEAVAA AGQSW L Sbjct 157 LPAQAGDALEELGYSQRQILERLRYLPLRPVGTQYAYSNFGLTTGAEAVAAIAGQSWAAL 216 Query 235 SDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLN 294 S + +Y PLGM TSS F DF AR N A H++V W+A R PDAQS AGGVSS++ Sbjct 217 SQQAVYGPLGMTQTSSLFADFEARANRAAGHLRVNGVWQAGPVRRPDAQSAAGGVSSTVR 276 Query 295 DMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSS 354 DM W+ M+L +G + GR++ +AL +PQ++ + P A +YG+GFNVGV+ + Sbjct 277 DMARWMTMLLDEGRFEGRQVVDAQALRTALSPQML-QSPAGSGEPARYYGFGFNVGVSEA 335 Query 355 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVRED 414 GRT YSHSGAFG G+A +F V+P L I+ LTN PIGVPE + ++F+D V++G+ R+D Sbjct 336 GRTTYSHSGAFGTGSATSFTVMPELKLGIVVLTNGMPIGVPEIVVSQFLDQVEWGRQRQD 395 Query 415 WAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHD--GQL 472 W +++ K AP+ + G LVGK P P P RPL YVG YAN ++GPA V+ G L Sbjct 396 WESIWTKRLAPIMQPHGELVGKTRPPFPRPPRPLGAYVGSYANRFYGPAQVSLQTGGGGL 455 Query 473 RLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYD 523 ++SLG +Q L+HWDG+ F+F E PGS+SKATF G+ L LEY+D Sbjct 456 QVSLG--SQRMLLSHWDGEVFSFV--PEGDSPGSLSKATFDGNQLTLEYFD 502 >gi|160896254|ref|YP_001561836.1| beta-lactamase [Delftia acidovorans SPH-1] gi|160361838|gb|ABX33451.1| beta-lactamase [Delftia acidovorans SPH-1] Length=519 Score = 445 bits (1144), Expect = 1e-122, Method: Compositional matrix adjust. Identities = 242/471 (52%), Positives = 319/471 (68%), Gaps = 11/471 (2%) Query 55 RIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADT 114 R+ A+ ++DG V M+ TG+PG+AVA+VH G+ +YA+G GVR +G VDADT Sbjct 41 RVKRALDQLDGQVRAQMRRTGVPGVAVAVVHEGRLVYAQGMGVRRLGS----SLAVDADT 96 Query 115 VFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSG 174 VFQLASVSKSVGATVVA V V+WDT V LPW+ L D ++T+ D+Y+HRSG Sbjct 97 VFQLASVSKSVGATVVAQQVGQRRVSWDTRVQQGLPWWTLEDADAAQRITVGDMYAHRSG 156 Query 175 LPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDL 234 LP AGD LE+LGY +RQ+L+RL+YLPL P YAY+NFG+T AEAVAA AGQSW L Sbjct 157 LPGQAGDALEELGYSQRQILERLRYLPLRPVGTQYAYSNFGLTTGAEAVAAIAGQSWAAL 216 Query 235 SDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLN 294 S + +Y PLGM TSS F DF AR N A H++V W+A R PDAQS AGGVSS++ Sbjct 217 SQQAVYGPLGMTQTSSLFADFEARANRAAGHLRVNGVWQAGPVRRPDAQSAAGGVSSTVR 276 Query 295 DMTHWLAMVLADGVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSS 354 DM W+ M+L +G + GR++ +AL +PQ++ + P A +YG+GFNVGV+ + Sbjct 277 DMARWMTMLLDEGRFEGRQVVDAQALRTALSPQML-QSPAGNGEPARYYGFGFNVGVSEA 335 Query 355 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVRED 414 GRT YSHSGAFG G+A +F V+P L I+ LTN PIGVPE + ++F+D V++G+ R+D Sbjct 336 GRTTYSHSGAFGTGSATSFTVMPELKLGIVVLTNGMPIGVPEIVVSQFLDQVEWGRQRQD 395 Query 415 WAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHD--GQL 472 W +++ K AP+ + G LVGK P P P RPL YVG YAN ++GPA V+ G L Sbjct 396 WESIWTKRLAPIMQPHGELVGKTRPPFPRPPRPLGAYVGSYANRFYGPAQVSLQTGGGGL 455 Query 473 RLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYD 523 ++SLG +Q L+HWDG+ F+F E PGS+SKATF G+ L LEY+D Sbjct 456 QVSLG--SQRMLLSHWDGEVFSFV--PEGDSPGSLSKATFDGNQLTLEYFD 502 Lambda K H 0.316 0.134 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1174401347248 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40