BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0913c

Length=502
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608053|ref|NP_215428.1|  dioxygenase [Mycobacterium tubercul...  1035    0.0   
gi|31792101|ref|NP_854594.1|  dioxygenase [Mycobacterium bovis AF...  1032    0.0   
gi|240172902|ref|ZP_04751561.1|  dioxygenase [Mycobacterium kansa...   917    0.0   
gi|183984581|ref|YP_001852872.1|  dioxygenase [Mycobacterium mari...   904    0.0   
gi|296169671|ref|ZP_06851289.1|  dioxygenase [Mycobacterium paras...   902    0.0   
gi|118616051|ref|YP_904383.1|  dioxygenase [Mycobacterium ulceran...   902    0.0   
gi|342860520|ref|ZP_08717171.1|  dioxygenase [Mycobacterium colom...   888    0.0   
gi|254822967|ref|ZP_05227968.1|  putative dioxygenase [Mycobacter...   886    0.0   
gi|226307980|ref|YP_002767940.1|  dioxygenase [Rhodococcus erythr...   820    0.0   
gi|118468583|ref|YP_889843.1|  carotenoid oxygenase [Mycobacteriu...   813    0.0   
gi|311741885|ref|ZP_07715696.1|  dioxygenase [Aeromicrobium marin...   803    0.0   
gi|229489090|ref|ZP_04382956.1|  dioxygenase [Rhodococcus erythro...   797    0.0   
gi|315442829|ref|YP_004075708.1|  lignostilbene-alpha,beta-dioxyg...   782    0.0   
gi|120405889|ref|YP_955718.1|  carotenoid oxygenase [Mycobacteriu...   781    0.0   
gi|145222397|ref|YP_001133075.1|  carotenoid oxygenase [Mycobacte...   781    0.0   
gi|126435697|ref|YP_001071388.1|  carotenoid oxygenase [Mycobacte...   732    0.0   
gi|108800064|ref|YP_640261.1|  carotenoid oxygenase [Mycobacteriu...   732    0.0   
gi|311741924|ref|ZP_07715735.1|  dioxygenase [Aeromicrobium marin...   731    0.0   
gi|103486497|ref|YP_616058.1|  carotenoid oxygenase [Sphingopyxis...   518    8e-145
gi|85373333|ref|YP_457395.1|  hypothetical protein ELI_02530 [Ery...   511    9e-143
gi|223940951|emb|CAQ43086.1|  hypothetical protein [Chondromyces ...   509    3e-142
gi|167645237|ref|YP_001682900.1|  carotenoid oxygenase [Caulobact...   509    6e-142
gi|85707934|ref|ZP_01039000.1|  hypothetical protein NAP1_01825 [...   507    2e-141
gi|16125029|ref|NP_419593.1|  hypothetical protein CC_0776 [Caulo...   495    9e-138
gi|295690938|ref|YP_003594631.1|  carotenoid oxygenase [Caulobact...   491    1e-136
gi|221065802|ref|ZP_03541907.1|  Carotenoid oxygenase [Comamonas ...   481    1e-133
gi|339328147|ref|YP_004687839.1|  apocarotenoid-15,15'-oxygenase ...   477    2e-132
gi|221065485|ref|ZP_03541590.1|  Carotenoid oxygenase [Comamonas ...   443    3e-122
gi|329894155|ref|ZP_08270140.1|  Carotenoid oxygenase [gamma prot...   400    3e-109
gi|300788787|ref|YP_003769078.1|  carotenoid cleavage dioxygenase...   378    1e-102
gi|271963075|ref|YP_003337271.1|  9-cis-epoxycarotenoid dioxygena...   369    1e-99 
gi|331699051|ref|YP_004335290.1|  9-cis-epoxycarotenoid dioxygena...   365    1e-98 
gi|254482257|ref|ZP_05095498.1|  Retinal pigment epithelial membr...   343    4e-92 
gi|124003789|ref|ZP_01688637.1|  retinal pigment epithelial membr...   339    6e-91 
gi|254515767|ref|ZP_05127827.1|  carotenoid cleavage dioxygenase ...   337    3e-90 
gi|84502108|ref|ZP_01000256.1|  possible dioxygenase [Oceanicola ...   331    2e-88 
gi|221065797|ref|ZP_03541902.1|  Carotenoid oxygenase [Comamonas ...   328    2e-87 
gi|341614431|ref|ZP_08701300.1|  9-cis-epoxycarotenoid dioxygenas...   319    9e-85 
gi|297180493|gb|ADI16707.1|  lignostilbene-alpha,beta-dioxygenase...   311    2e-82 
gi|339328145|ref|YP_004687837.1|  apocarotenoid-15,15'-oxygenase ...   309    7e-82 
gi|172037130|ref|YP_001803631.1|  retinal pigment epithelial memb...   301    3e-79 
gi|67920149|ref|ZP_00513669.1|  Retinal pigment epithelial membra...   295    2e-77 
gi|126656544|ref|ZP_01727805.1|  Retinal pigment epithelial membr...   292    9e-77 
gi|75909914|ref|YP_324210.1|  retinal pigment epithelial membrane...   291    2e-76 
gi|17228601|ref|NP_485149.1|  hypothetical protein all1106 [Nosto...   288    1e-75 
gi|119511691|ref|ZP_01630796.1|  Retinal pigment epithelial membr...   288    2e-75 
gi|254410750|ref|ZP_05024528.1|  Retinal pigment epithelial membr...   286    5e-75 
gi|186683149|ref|YP_001866345.1|  carotenoid oxygenase [Nostoc pu...   283    5e-74 
gi|75908268|ref|YP_322564.1|  retinal pigment epithelial membrane...   283    6e-74 
gi|113477252|ref|YP_723313.1|  carotenoid oxygenase [Trichodesmiu...   282    1e-73 


>gi|15608053|ref|NP_215428.1| dioxygenase [Mycobacterium tuberculosis H37Rv]
 gi|15840334|ref|NP_335371.1| dioxygenase, putative [Mycobacterium tuberculosis CDC1551]
 gi|121636836|ref|YP_977059.1| putative dioxygenase [Mycobacterium bovis BCG str. Pasteur 1173P2]
 78 more sequence titles
 Length=502

 Score = 1035 bits (2676),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 502/502 (100%), Positives = 502/502 (100%), Gaps = 0/502 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP
Sbjct  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA
Sbjct  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD
Sbjct  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA  300
            NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA
Sbjct  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA  300

Query  301  YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL  360
            YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL
Sbjct  301  YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL  360

Query  361  SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE  420
            SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE
Sbjct  361  SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE  420

Query  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480
            TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
Sbjct  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480

Query  481  WVPGAELRRWDHAESPAAAVGL  502
            WVPGAELRRWDHAESPAAAVGL
Sbjct  481  WVPGAELRRWDHAESPAAAVGL  502


>gi|31792101|ref|NP_854594.1| dioxygenase [Mycobacterium bovis AF2122/97]
 gi|31617689|emb|CAD93798.1| POSSIBLE DIOXYGENASE [Mycobacterium bovis AF2122/97]
Length=502

 Score = 1032 bits (2668),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 501/502 (99%), Positives = 501/502 (99%), Gaps = 0/502 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP
Sbjct  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA
Sbjct  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD
Sbjct  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRL HDMAFTE
Sbjct  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLLHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA  300
            NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA
Sbjct  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA  300

Query  301  YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL  360
            YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL
Sbjct  301  YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL  360

Query  361  SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE  420
            SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE
Sbjct  361  SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE  420

Query  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480
            TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
Sbjct  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480

Query  481  WVPGAELRRWDHAESPAAAVGL  502
            WVPGAELRRWDHAESPAAAVGL
Sbjct  481  WVPGAELRRWDHAESPAAAVGL  502


>gi|240172902|ref|ZP_04751561.1| dioxygenase [Mycobacterium kansasii ATCC 12478]
Length=504

 Score =  917 bits (2369),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/504 (88%), Positives = 461/504 (92%), Gaps = 2/504 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M + IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDAD LT V G +P DLDGIYLRNTENP
Sbjct  1    MHVEIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADALTAVEGAIPRDLDGIYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPAF TYHPFDGDGM+HVVGFRDGK+FYRNRF++T+GFLAENEAGGPLWPGLAEPVQ A
Sbjct  61   LHPAFKTYHPFDGDGMVHVVGFRDGKSFYRNRFVQTEGFLAENEAGGPLWPGLAEPVQFA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR+ GWGAR LMKDASSTDVIVHRGIALTSFYQCGDLYR+DPYS NTLGKE+W+G FPF 
Sbjct  121  KRDTGWGARTLMKDASSTDVIVHRGIALTSFYQCGDLYRLDPYSGNTLGKETWNGHFPFG  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD+ TGELLFFNYSKQEPYM YGVVDQNNEL HYVD+PLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDSGTGELLFFNYSKQEPYMHYGVVDQNNELAHYVDIPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFT  298
            NY ILNDFPLFWDPRLLE +VHLPRFYP++PSRFAV+ RRG   DIRWFEA+PTFVLHFT
Sbjct  241  NYAILNDFPLFWDPRLLEHNVHLPRFYPDMPSRFAVIPRRGLSGDIRWFEAEPTFVLHFT  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
            NAYE GDEIVLDGFYE DPQPLDTGGTKWEKLFRFLALDRLQ+RLHRWRLN+VTGAV EE
Sbjct  301  NAYEDGDEIVLDGFYEADPQPLDTGGTKWEKLFRFLALDRLQTRLHRWRLNLVTGAVKEE  360

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
            QLSESITEFGTIN  YAA  YRY YAATGKP WFLFDGLVKHDL TGN E YSFGDGVYG
Sbjct  361  QLSESITEFGTINDGYAARQYRYAYAATGKPGWFLFDGLVKHDLFTGNQEGYSFGDGVYG  420

Query  419  SETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
            SET MAPRVG +AEDDGYLVTLTTDMNDD SYCLVFDAAR GDGP+CKL LPERISSGTH
Sbjct  421  SETQMAPRVGGTAEDDGYLVTLTTDMNDDTSYCLVFDAARVGDGPVCKLQLPERISSGTH  480

Query  479  SAWVPGAELRRWDHAESPAAAVGL  502
            S WVPGAELRRW HAESPA AVGL
Sbjct  481  STWVPGAELRRWHHAESPAGAVGL  504


>gi|183984581|ref|YP_001852872.1| dioxygenase [Mycobacterium marinum M]
 gi|183177907|gb|ACC43017.1| dioxygenase [Mycobacterium marinum M]
Length=506

 Score =  904 bits (2337),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 432/506 (86%), Positives = 463/506 (92%), Gaps = 4/506 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGKYLSTLPEDDDHPYRTGPWRPQTTEW+ADDLT V GE+P DLDG+YLRNTENP
Sbjct  1    MDVEIVGKYLSTLPEDDDHPYRTGPWRPQTTEWNADDLTVVEGEIPHDLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPAF TYHPFDGDGM+HVVGFRDGKAFYRNRFI+TDGF AENEAG PLWPGLAEP+QLA
Sbjct  61   LHPAFKTYHPFDGDGMLHVVGFRDGKAFYRNRFIQTDGFQAENEAGEPLWPGLAEPIQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR+ GWGAR LMKDASSTDVIVHRGIALTSFYQCGDLYR+DP SA TLGKE+W G FPFD
Sbjct  121  KRDQGWGARTLMKDASSTDVIVHRGIALTSFYQCGDLYRVDPSSATTLGKENWSGNFPFD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD KTGELLFFNYSKQEPYMRYGVVDQ+NEL HYVD+PLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDGKTGELLFFNYSKQEPYMRYGVVDQDNELAHYVDIPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NY ILNDFPLFWDP+LLE ++HLPRFYP++PSRFAV+ RRG+  DIRWFEADPTFVLHFT
Sbjct  241  NYAILNDFPLFWDPQLLEHNLHLPRFYPDMPSRFAVIPRRGSTADIRWFEADPTFVLHFT  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGG--TKWEKLFRFLALDRLQSRLHRWRLNMVTGAVH  356
            NAYE+GDEIVLDGF+EG P PL+T    TKWEKLFRFLALDRLQ+RLHRWRLN+VTGAV 
Sbjct  301  NAYEEGDEIVLDGFFEGAPHPLETSASSTKWEKLFRFLALDRLQTRLHRWRLNLVTGAVK  360

Query  357  EEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGV  416
            EE+LSESITEFGTIN+DYAA  YRY YAATGKP WFLFDGLVKHDLLTGN E  SFG+GV
Sbjct  361  EERLSESITEFGTINSDYAARQYRYAYAATGKPGWFLFDGLVKHDLLTGNQEGISFGEGV  420

Query  417  YGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSG  476
            YGSET MAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAAR  DGP+CKL LPERISSG
Sbjct  421  YGSETQMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLELPERISSG  480

Query  477  THSAWVPGAELRRWDHAESPAAAVGL  502
            THS WVPG ELRRW HA+S  +A+GL
Sbjct  481  THSTWVPGNELRRWHHADSAPSAIGL  506


>gi|296169671|ref|ZP_06851289.1| dioxygenase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895668|gb|EFG75364.1| dioxygenase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=504

 Score =  902 bits (2331),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 429/504 (86%), Positives = 462/504 (92%), Gaps = 2/504 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGK+LSTLPEDDDHPYRTGPWRPQTTEWDADDL  V GE+P DLDGIYLRNTENP
Sbjct  1    MDVEIVGKFLSTLPEDDDHPYRTGPWRPQTTEWDADDLIAVEGEIPHDLDGIYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPA  TYHPFDGDGM+HVVGFRDGKAFYRNRF+RTDGFLAENEAGGPLWPGLAEPVQLA
Sbjct  61   LHPALKTYHPFDGDGMLHVVGFRDGKAFYRNRFVRTDGFLAENEAGGPLWPGLAEPVQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KRE GWGAR  MKDASSTDV+VHRG+ALTSFYQCGDLYR++PYS  TLGKESW+GRFP D
Sbjct  121  KREDGWGARTRMKDASSTDVVVHRGVALTSFYQCGDLYRVNPYSGETLGKESWNGRFPSD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVDNKTGELLFFNYSK+EPYMRYGVVD N+ELVHYVD+PLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDNKTGELLFFNYSKREPYMRYGVVDGNDELVHYVDIPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFT  298
            NYVILNDFPLFWDP LLE DVHLPRFYP++PSRFA++ RRG  +DIRWFEA+PTFVLHF 
Sbjct  241  NYVILNDFPLFWDPTLLEHDVHLPRFYPDMPSRFAILPRRGGTHDIRWFEAEPTFVLHFV  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
            NAYE GDEIVLDGF+EGDP P+D GG+KW+KLFRFLALDRLQSRLHRWR N+ TGAVHEE
Sbjct  301  NAYEDGDEIVLDGFFEGDPSPIDNGGSKWDKLFRFLALDRLQSRLHRWRFNLTTGAVHEE  360

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
            +LSESITEFGTIN DYAA +YRY YAATGKP WFLFDGLVKHDL TG+ + +SFGDGVYG
Sbjct  361  RLSESITEFGTINPDYAAGNYRYAYAATGKPGWFLFDGLVKHDLRTGSQQEFSFGDGVYG  420

Query  419  SETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
            SETAMAPRVG+S EDDGYLVTLTTDMN DASYC+VFDAAR GDGP+CKL LPERISSGTH
Sbjct  421  SETAMAPRVGASGEDDGYLVTLTTDMNTDASYCVVFDAARLGDGPVCKLRLPERISSGTH  480

Query  479  SAWVPGAELRRWDHAESPAAAVGL  502
            S W PG +LRRWD AES A AVGL
Sbjct  481  STWAPGEQLRRWDTAESAAMAVGL  504


>gi|118616051|ref|YP_904383.1| dioxygenase [Mycobacterium ulcerans Agy99]
 gi|118568161|gb|ABL02912.1| dioxygenase [Mycobacterium ulcerans Agy99]
Length=506

 Score =  902 bits (2330),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 431/506 (86%), Positives = 463/506 (92%), Gaps = 4/506 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGKYLSTLPEDDDHPYRTGPWRPQTTEW+ADDLT V GE+P DLDG+YLRNTENP
Sbjct  1    MDVEIVGKYLSTLPEDDDHPYRTGPWRPQTTEWNADDLTVVEGEIPHDLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPAF TYHPFDGDGM+HVVGFRDGKAFYRNRFI+TDGF AENEAG PLWPGLAEP+QLA
Sbjct  61   LHPAFKTYHPFDGDGMLHVVGFRDGKAFYRNRFIQTDGFRAENEAGEPLWPGLAEPIQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR+ GWGAR LMKDASSTDVIV+RGIALTSFYQCGDLYR+DP SA TLGKE+W G FPFD
Sbjct  121  KRDQGWGARTLMKDASSTDVIVYRGIALTSFYQCGDLYRVDPSSATTLGKETWSGHFPFD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD KTGELLFFNYSKQEPYMRYGVVDQ+NEL HYVD+PLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDGKTGELLFFNYSKQEPYMRYGVVDQDNELAHYVDIPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NY ILNDFPLFWDP+LLE ++HLPRFYP++PSRFAV+ RRG+  DIRWFEADPTFVLHFT
Sbjct  241  NYAILNDFPLFWDPQLLEHNLHLPRFYPDMPSRFAVIPRRGSTADIRWFEADPTFVLHFT  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGG--TKWEKLFRFLALDRLQSRLHRWRLNMVTGAVH  356
            NAYE+GDEIVLDGF+EG P PL+T    TKWEKLFRFLALDRLQ+RLHRWRLN+VTGAV 
Sbjct  301  NAYEEGDEIVLDGFFEGAPHPLETSASSTKWEKLFRFLALDRLQTRLHRWRLNLVTGAVK  360

Query  357  EEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGV  416
            EE+LSESITEFGTIN+DYAA  YRY YAATGKP WFLFDGLVKHDLLTGN E  SFG+GV
Sbjct  361  EERLSESITEFGTINSDYAARQYRYAYAATGKPGWFLFDGLVKHDLLTGNQEGISFGEGV  420

Query  417  YGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSG  476
            YGSET MAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAAR  DGP+CKL LPERISSG
Sbjct  421  YGSETQMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLELPERISSG  480

Query  477  THSAWVPGAELRRWDHAESPAAAVGL  502
            THS WVPG ELRRW HA+S  +A+GL
Sbjct  481  THSTWVPGNELRRWHHADSAPSAIGL  506


>gi|342860520|ref|ZP_08717171.1| dioxygenase [Mycobacterium colombiense CECT 3035]
 gi|342132175|gb|EGT85416.1| dioxygenase [Mycobacterium colombiense CECT 3035]
Length=504

 Score =  888 bits (2295),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/504 (85%), Positives = 456/504 (91%), Gaps = 2/504 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGK LSTLPEDDDHPYRTGPWRPQTTEWDADDL  V GE+P DLDG+YLRNTENP
Sbjct  1    MDVEIVGKLLSTLPEDDDHPYRTGPWRPQTTEWDADDLIAVEGEIPGDLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPA  TYHPFDGDGM+HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA
Sbjct  61   LHPALKTYHPFDGDGMVHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            +RE GWGAR  MKDASSTDVIVHRG+ALTSFYQCGDLYRIDPYSA TLGKESW+G FP +
Sbjct  121  RREQGWGARTKMKDASSTDVIVHRGVALTSFYQCGDLYRIDPYSAGTLGKESWNGGFPAE  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVDN+TGELLFFNYSKQEPYM YGVVD+ NEL HYVD+PLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDNRTGELLFFNYSKQEPYMHYGVVDERNELAHYVDIPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFT  298
            NY ILNDFPLFWDP+LLE DVHLPRFYP++PSRFAV+ RRG   DIRWFEADPTFVLHFT
Sbjct  241  NYAILNDFPLFWDPQLLEHDVHLPRFYPDLPSRFAVIPRRGGTGDIRWFEADPTFVLHFT  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
            NAYE GDEIVLDGF+EGDP PLDTGGTKWEKLFRFLALDRLQ+RLHRWR N+VTGAV EE
Sbjct  301  NAYEDGDEIVLDGFFEGDPSPLDTGGTKWEKLFRFLALDRLQARLHRWRFNLVTGAVREE  360

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
            +LS+SITEFGTIN ++   +YRYTYAATGKP WFLFDGLVKHDL TG  E +SFGDGVYG
Sbjct  361  RLSDSITEFGTINPEHTGGAYRYTYAATGKPGWFLFDGLVKHDLRTGTEEGFSFGDGVYG  420

Query  419  SETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
            SETAMAPRVG+  EDDGYLVTLTTDMN DASYCLVFDAAR GDGP+CKL LPERISSGTH
Sbjct  421  SETAMAPRVGARGEDDGYLVTLTTDMNTDASYCLVFDAARVGDGPVCKLQLPERISSGTH  480

Query  479  SAWVPGAELRRWDHAESPAAAVGL  502
            S W PGA+LRRW  A S A A+GL
Sbjct  481  STWAPGAQLRRWATAASAAGAIGL  504


>gi|254822967|ref|ZP_05227968.1| putative dioxygenase [Mycobacterium intracellulare ATCC 13950]
Length=508

 Score =  886 bits (2289),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 424/503 (85%), Positives = 453/503 (91%), Gaps = 2/503 (0%)

Query  2    DITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPL  61
            DI IVGK+LSTLPEDDDHPYRTGPWRPQTTEWDADDL  V GE+P DLDG+YLRNTENPL
Sbjct  6    DIAIVGKFLSTLPEDDDHPYRTGPWRPQTTEWDADDLAAVEGEIPGDLDGVYLRNTENPL  65

Query  62   HPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAK  121
            H AF TYHPFDGDGM+HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA+
Sbjct  66   HLAFKTYHPFDGDGMLHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAQ  125

Query  122  REHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDW  181
               GWGAR  MKDASSTDVIVHRG+AL+SFYQCGDLYRIDPYS +TLGKESW+GRFP  W
Sbjct  126  GPQGWGARTRMKDASSTDVIVHRGVALSSFYQCGDLYRIDPYSGDTLGKESWNGRFPTAW  185

Query  182  GVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTEN  241
            GVSAHPKVDN TGELLFFNYSKQ+PYM YGVVD+ NEL HYVD+PLPGPRLPHDMAFTEN
Sbjct  186  GVSAHPKVDNATGELLFFNYSKQDPYMHYGVVDERNELTHYVDIPLPGPRLPHDMAFTEN  245

Query  242  YVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTN  299
            Y ILNDFPLFWDP+LLE DVHLPRF+P+IPSRFAV+ RRG   DIRWFEADPTFVLHFTN
Sbjct  246  YAILNDFPLFWDPQLLEHDVHLPRFHPDIPSRFAVIPRRGGTEDIRWFEADPTFVLHFTN  305

Query  300  AYEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQ  359
            AYE GDEIVLDGF+EGDP PLDTGGTKW+KLFRFLALDRLQ+RLHRWR N+VTG V EE+
Sbjct  306  AYEDGDEIVLDGFFEGDPSPLDTGGTKWDKLFRFLALDRLQARLHRWRFNLVTGEVREER  365

Query  360  LSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGS  419
            L ES+TEFGTIN  YAA+ YRY YAATGKP WFLFDGLVKHDL TG  E +SFGDGVYGS
Sbjct  366  LFESVTEFGTINPGYAAADYRYVYAATGKPGWFLFDGLVKHDLRTGTEERFSFGDGVYGS  425

Query  420  ETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHS  479
            ETAMAPRVG + EDDGYL+TLTTDMN DASYCLVFDA RPGDGP+CKL LPERISSGTHS
Sbjct  426  ETAMAPRVGGTGEDDGYLITLTTDMNTDASYCLVFDATRPGDGPVCKLPLPERISSGTHS  485

Query  480  AWVPGAELRRWDHAESPAAAVGL  502
             W PG+ELRRWD AES A A+GL
Sbjct  486  TWAPGSELRRWDTAESAADAIGL  508


>gi|226307980|ref|YP_002767940.1| dioxygenase [Rhodococcus erythropolis PR4]
 gi|226187097|dbj|BAH35201.1| putative dioxygenase [Rhodococcus erythropolis PR4]
Length=505

 Score =  820 bits (2118),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 385/505 (77%), Positives = 437/505 (87%), Gaps = 3/505 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGK LSTLP DDDHPYRTGPW+PQTTE+ AD+L  V GEVP DLDG+YLRNTENP
Sbjct  1    MDVEIVGKLLSTLPADDDHPYRTGPWQPQTTEFKADNLEVVFGEVPKDLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHP+   YHPFDGDGMIH+VGFRDG++FYRNRF+RTDG  AE +AGG LW GLAE  +L+
Sbjct  61   LHPSMKAYHPFDGDGMIHIVGFRDGESFYRNRFVRTDGLAAEQDAGGALWAGLAESPKLS  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            + E G GAR  MKDASSTDV+VHRG ALTSFYQCGDLYR+DP SA TLGKESW+G+FPF+
Sbjct  121  RPEGGKGARTRMKDASSTDVVVHRGTALTSFYQCGDLYRLDPMSAETLGKESWNGKFPFE  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD+KTGE+LFFNYSK+ PYM YGVVD  NELVHYVDVPLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDDKTGEMLFFNYSKEAPYMHYGVVDSANELVHYVDVPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NY ILND PLFWDP LLE+  H+  F+P+IP R  V+ RRGN  DI+WFEADPT+VLHF 
Sbjct  241  NYAILNDCPLFWDPVLLEKGAHVANFHPDIPLRLGVIPRRGNTADIKWFEADPTYVLHFV  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTG-GTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE+GDEIVLDGFY+GDP+P D G G +WE+ FRFLALDR+Q+RLHRWRLN+VTGA  E
Sbjct  301  NAYEEGDEIVLDGFYQGDPEPSDNGMGNQWERAFRFLALDRMQTRLHRWRLNLVTGATRE  360

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            EQLS+SITEFG +N ++A   YRY YAA+GKPSWFLFDGLVKHDLLTGN E +SFGDGVY
Sbjct  361  EQLSDSITEFGMMNGNFAGEKYRYAYAASGKPSWFLFDGLVKHDLLTGNEERFSFGDGVY  420

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSET+MAPRVG +AEDDGYL+TLTTDMN+DAS+CL+FDAAR GDGP+CKL LPERISSGT
Sbjct  421  GSETSMAPRVGGTAEDDGYLITLTTDMNEDASFCLIFDAARVGDGPLCKLRLPERISSGT  480

Query  478  HSAWVPGAELRRWDHAESPAAAVGL  502
            HS W PGAELRRW  A++ A AVGL
Sbjct  481  HSTWAPGAELRRWQSADTAAEAVGL  505


>gi|118468583|ref|YP_889843.1| carotenoid oxygenase [Mycobacterium smegmatis str. MC2 155]
 gi|118169870|gb|ABK70766.1| carotenoid oxygenase [Mycobacterium smegmatis str. MC2 155]
Length=507

 Score =  813 bits (2101),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/507 (75%), Positives = 434/507 (86%), Gaps = 5/507 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M   +V KYLSTLPEDD HPYRTG WRPQTTEWDADDLT V GE+PADLDG+YLRNTENP
Sbjct  1    MHTEVVAKYLSTLPEDDTHPYRTGAWRPQTTEWDADDLTVVEGEIPADLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            +HPAF  YHPFDGDGM+HVVGFRDGKAFYRNRF+RTDG L EN  GGPLWPG+AEPV+LA
Sbjct  61   MHPAFKVYHPFDGDGMLHVVGFRDGKAFYRNRFVRTDGLLEENAEGGPLWPGIAEPVELA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR++GWGAR LMKDASSTDV VHRG+ALTSFYQCGDLYRI+P++ +TLGKE+W+G FP D
Sbjct  121  KRDYGWGARTLMKDASSTDVTVHRGVALTSFYQCGDLYRINPHTGDTLGKENWNGGFPVD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPK D++TGELLFFNY KQ PYM +GVVDQNN LVHY DV LPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKNDDRTGELLFFNYGKQAPYMHFGVVDQNNNLVHYTDVELPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA  300
            NYVILNDFP+FWD   L+ + H+PR + ++PSRFAVV RRG DI+WFEAD T+VLHFTNA
Sbjct  241  NYVILNDFPMFWDAEFLKHNAHIPRLHRDLPSRFAVVPRRGGDIKWFEADTTYVLHFTNA  300

Query  301  YEQGDEIVLDGFYEGDPQ----PLDTGGT-KWEKLFRFLALDRLQSRLHRWRLNMVTGAV  355
            +E GDEIV+DGF++G P+    P D G + KW++ FR+L+LD +Q+RLHRWR N+VTG  
Sbjct  301  FEDGDEIVMDGFFQGSPEPDDDPADNGMSRKWQRFFRYLSLDGMQTRLHRWRFNLVTGET  360

Query  356  HEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDG  415
             EEQLS+S+TEFG IN D+A   YRY YAATGKP WFLFDGLV+HDL TG+ E Y+F DG
Sbjct  361  REEQLSDSLTEFGMINPDFATQDYRYIYAATGKPGWFLFDGLVRHDLRTGSEERYTFADG  420

Query  416  VYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISS  475
            VYGSETAMAPRVG S EDDGYLVTL +DMNDDASYCLVFDAAR GDGP+CKLALPERISS
Sbjct  421  VYGSETAMAPRVGGSGEDDGYLVTLISDMNDDASYCLVFDAARVGDGPVCKLALPERISS  480

Query  476  GTHSAWVPGAELRRWDHAESPAAAVGL  502
            GTHS WV GAELRRW  ++  AAA+G+
Sbjct  481  GTHSTWVSGAELRRWHTSDDAAAAIGM  507


>gi|311741885|ref|ZP_07715696.1| dioxygenase [Aeromicrobium marinum DSM 15272]
 gi|311314891|gb|EFQ84797.1| dioxygenase [Aeromicrobium marinum DSM 15272]
Length=505

 Score =  803 bits (2073),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 376/505 (75%), Positives = 425/505 (85%), Gaps = 3/505 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ +VG+ LSTLPEDDDHPYRTGPW+PQTTEW ADDL  V GE+PADLDG+YLRNTENP
Sbjct  1    MDVDVVGRILSTLPEDDDHPYRTGPWQPQTTEWKADDLEVVQGEIPADLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            +HP+   YHPFDGDGM+HVVGFRDG AFYRNRFIRTDG  AE EAGGPLW GLAEP +LA
Sbjct  61   VHPSLKNYHPFDGDGMLHVVGFRDGSAFYRNRFIRTDGLAAEAEAGGPLWAGLAEPPKLA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
             RE GWG+R  MKDASSTDVIVHRG ALTSFYQCGDLYR+DP SA TLGKESW G FP D
Sbjct  121  LREDGWGSRTRMKDASSTDVIVHRGTALTSFYQCGDLYRVDPMSAETLGKESWGGAFPSD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD++TGE+LFFNYSK+ PYM YGVVD  N L HYVDVPLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDDRTGEMLFFNYSKEAPYMHYGVVDDTNTLTHYVDVPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFT  298
            NY ILND PLFWD  LL++D H+ RF P++P+RFAV+ R+G   DIRWFEA+ T+VLHF 
Sbjct  241  NYAILNDCPLFWDEELLKKDAHVARFRPDLPTRFAVIPRKGETKDIRWFEAESTYVLHFV  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTG-GTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE GDEIVLDGF++ DP+P D G G +W++ FRFLALDR+QSRLHRWRLN+VTG V E
Sbjct  301  NAYEDGDEIVLDGFFQADPEPADNGMGDQWQRAFRFLALDRMQSRLHRWRLNLVTGLVKE  360

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            EQLS+SITEFG +N  Y    YRY YAATGKPSWFLFDGLVKHDL  G  E + FGDGVY
Sbjct  361  EQLSDSITEFGVMNGAYTGGEYRYAYAATGKPSWFLFDGLVKHDLKDGTEERFGFGDGVY  420

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSETAMAPR+G++ EDDGYL+TLTTDMN DAS+C+V DAAR  DGP+C L LPERISSGT
Sbjct  421  GSETAMAPRIGATGEDDGYLITLTTDMNQDASFCVVLDAARVSDGPVCTLRLPERISSGT  480

Query  478  HSAWVPGAELRRWDHAESPAAAVGL  502
            H+ W PGA+LRRW  A++ A A+GL
Sbjct  481  HATWAPGADLRRWQTADTAADAIGL  505


>gi|229489090|ref|ZP_04382956.1| dioxygenase [Rhodococcus erythropolis SK121]
 gi|229324594|gb|EEN90349.1| dioxygenase [Rhodococcus erythropolis SK121]
Length=505

 Score =  797 bits (2058),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 383/505 (76%), Positives = 435/505 (87%), Gaps = 3/505 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ IVGK LSTLP DDDHPYRTGPW+PQTTE+ AD+L  V GEVP DLDG+YLRNTENP
Sbjct  1    MDVEIVGKLLSTLPADDDHPYRTGPWQPQTTEFKADNLEVVFGEVPKDLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHP+   YHPFDGDGMIH+VGFRDG++FYRNRF+RTDG  AE +AG  LW GLAE  +L+
Sbjct  61   LHPSMKAYHPFDGDGMIHIVGFRDGESFYRNRFVRTDGLAAEQDAGAALWAGLAESPKLS  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            + E G GAR  MKDASSTDV+VHRG ALTSFYQCGDLYR+DP SA TLGKESW+G+FPF+
Sbjct  121  RPEGGKGARTRMKDASSTDVVVHRGTALTSFYQCGDLYRLDPMSAETLGKESWNGKFPFE  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD+KTGE+LFFNYSK+ PYM YGVVD  NELVHYVDVPLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKVDDKTGEMLFFNYSKEAPYMHYGVVDSANELVHYVDVPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NY ILND PLFWDP LLE+  H+  F+P+IP R  V+ RRGN  DI+WFEAD T+VLHF 
Sbjct  241  NYAILNDCPLFWDPVLLEKGAHVANFHPDIPLRLGVIPRRGNTSDIKWFEADSTYVLHFV  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTG-GTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE+GDEIVLDGFY+GDP+P D G G +WE+ FRFLALDR+Q+RLHRWRLN+VTGA  E
Sbjct  301  NAYEEGDEIVLDGFYQGDPEPSDNGMGNQWERAFRFLALDRMQTRLHRWRLNLVTGATRE  360

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            EQLS+SITEFG +N ++A   YRY YAA+GKPSWFLFDGLVKHDLLTGN E +SFGDGVY
Sbjct  361  EQLSDSITEFGMMNGNFAGEKYRYAYAASGKPSWFLFDGLVKHDLLTGNEERFSFGDGVY  420

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSET+MAPRVG +AEDDGYL+TLTTDMN+DAS+CL+FDAAR GDGP+CKL LPERISSGT
Sbjct  421  GSETSMAPRVGGTAEDDGYLITLTTDMNEDASFCLIFDAARVGDGPLCKLRLPERISSGT  480

Query  478  HSAWVPGAELRRWDHAESPAAAVGL  502
            HS W PGAELRRW  A++ A AVGL
Sbjct  481  HSTWAPGAELRRWQSADTAAEAVGL  505


>gi|315442829|ref|YP_004075708.1| lignostilbene-alpha,beta-dioxygenase-like enzyme [Mycobacterium 
sp. Spyr1]
 gi|315261132|gb|ADT97873.1| lignostilbene-alpha,beta-dioxygenase-like enzyme [Mycobacterium 
sp. Spyr1]
Length=512

 Score =  782 bits (2020),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 373/504 (75%), Positives = 428/504 (85%), Gaps = 6/504 (1%)

Query  5    IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPA  64
            +VGK+LSTLPEDDDHPYRTGPWRPQTTEWD DDL  V G++P DLDG+YLRNTENPLHPA
Sbjct  9    VVGKFLSTLPEDDDHPYRTGPWRPQTTEWDDDDLRVVEGQIPGDLDGVYLRNTENPLHPA  68

Query  65   FATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREH  124
               YHPFDGDGM+H+VGFRDGKAFYRNRF+RTD   AENEAGGPLWPG+AEP++LAKR++
Sbjct  69   LKYYHPFDGDGMLHMVGFRDGKAFYRNRFVRTDALAAENEAGGPLWPGIAEPIELAKRDY  128

Query  125  GWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVS  184
            GWGAR LMKDASSTDVIVHRG+ALTS YQCGDLYRIDP +   LGKE W+G FP DWGVS
Sbjct  129  GWGARTLMKDASSTDVIVHRGVALTSHYQCGDLYRIDPCTGADLGKEDWNGGFPTDWGVS  188

Query  185  AHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVI  244
            AHPKVD++TGELLFFNYSKQ P+MRYGVV    ++VH VDVPLPGPRLPHDMAFTENYVI
Sbjct  189  AHPKVDDRTGELLFFNYSKQAPFMRYGVVSPAGDVVHNVDVPLPGPRLPHDMAFTENYVI  248

Query  245  LNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYE  302
            LNDFPLFWD  LLE ++HLPRF+ ++PSRFAV+ RRG+   I WFEADPT+VLHF NA+E
Sbjct  249  LNDFPLFWDTGLLEHNIHLPRFHRDVPSRFAVLPRRGDTSQIMWFEADPTYVLHFPNAFE  308

Query  303  QGDEIVLDGFYEGDPQP---LDTGGT-KWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
             GDEIVLDGF++GDP+P   +D G + KW+++FR L+LD +Q+RLHRWR N+ TGAV EE
Sbjct  309  DGDEIVLDGFFQGDPEPTQGVDNGMSRKWQQIFRSLSLDGMQTRLHRWRFNLKTGAVREE  368

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
             LS+S TEFG IN  ++   +RYTYAATGKP WFLFDGLVKHDL TG  + ++F DGV+G
Sbjct  369  HLSDSFTEFGMINPGFSGRPHRYTYAATGKPGWFLFDGLVKHDLHTGTEQRFTFDDGVFG  428

Query  419  SETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
            SETAMAPRVG + EDDGYLVTLTTDMN DASYCLVFDAAR GDGP+CKL LPERISSGTH
Sbjct  429  SETAMAPRVGGTDEDDGYLVTLTTDMNTDASYCLVFDAARVGDGPVCKLQLPERISSGTH  488

Query  479  SAWVPGAELRRWDHAESPAAAVGL  502
            S W  G +L RW  +ES A A+GL
Sbjct  489  STWAAGCDLPRWRDSESAAGAIGL  512


>gi|120405889|ref|YP_955718.1| carotenoid oxygenase [Mycobacterium vanbaalenii PYR-1]
 gi|119958707|gb|ABM15712.1| Carotenoid oxygenase [Mycobacterium vanbaalenii PYR-1]
Length=537

 Score =  781 bits (2017),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 379/529 (72%), Positives = 427/529 (81%), Gaps = 31/529 (5%)

Query  5    IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPA  64
            IVGK+LSTLPEDDDHPYRTGPWRPQTTEWD DDL  V G +P DLDG+YLRNTENPLHPA
Sbjct  9    IVGKFLSTLPEDDDHPYRTGPWRPQTTEWDDDDLKVVEGRIPDDLDGVYLRNTENPLHPA  68

Query  65   FATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREH  124
               YHPFDGDGM+H+VGFRDGKAFYRNRF+RTD F  ENEAGGPLWPG+AEP++LA+R++
Sbjct  69   LKYYHPFDGDGMLHIVGFRDGKAFYRNRFVRTDAFAEENEAGGPLWPGIAEPLELARRDY  128

Query  125  GWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVS  184
            GWGAR LMKDASSTDV+VHRG+ALTS YQCGDLYRIDP +   LGKE WHG FP DWGVS
Sbjct  129  GWGARTLMKDASSTDVVVHRGVALTSHYQCGDLYRIDPRTGAALGKEDWHGTFPSDWGVS  188

Query  185  AHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVI  244
            AHPK+D+ TGELLFFNYSKQ PYMRYGVV    E+VH VDVPLPGPRLPHDMAFTENYVI
Sbjct  189  AHPKIDDHTGELLFFNYSKQAPYMRYGVVSPAGEVVHNVDVPLPGPRLPHDMAFTENYVI  248

Query  245  LNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYE  302
            LNDFPLFWD  LLE ++H PRF+ ++PSRFAVV RRG+   I+WFE  PT+VLHF NAYE
Sbjct  249  LNDFPLFWDTGLLEHNIHFPRFHRDMPSRFAVVPRRGDTSQIKWFETAPTYVLHFPNAYE  308

Query  303  QGDEIVLDGFYEGDPQP---LDTGGT-KWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
             GDEIVLDGF++GDP+P   +D G + KW ++FR L+LD +Q+RLHRWR N+VTG   EE
Sbjct  309  DGDEIVLDGFFQGDPEPTDGVDNGMSGKWRQIFRSLSLDGMQTRLHRWRFNLVTGEAREE  368

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
            QLS+SITEFG IN  Y+   YRYTYAATGKP WFLFDGLV+HDL TG  + Y FGDGVYG
Sbjct  369  QLSDSITEFGMINPAYSGRPYRYTYAATGKPGWFLFDGLVRHDLHTGTEQRYGFGDGVYG  428

Query  419  SETAMAPRV-------------------------GSSAEDDGYLVTLTTDMNDDASYCLV  453
            SETAMAPRV                         GS+AEDDGYLVTLTTDM  DASYCLV
Sbjct  429  SETAMAPRVGSAAADHIGGSAAAHIGGSAAAHIGGSAAEDDGYLVTLTTDMAADASYCLV  488

Query  454  FDAARPGDGPICKLALPERISSGTHSAWVPGAELRRWDHAESPAAAVGL  502
            FDAAR GDGP+CKL LPERISSGTHS W PGA+L +W  ++S A A+GL
Sbjct  489  FDAARVGDGPVCKLQLPERISSGTHSTWAPGADLPQWRESDSAAGAIGL  537


>gi|145222397|ref|YP_001133075.1| carotenoid oxygenase [Mycobacterium gilvum PYR-GCK]
 gi|145214883|gb|ABP44287.1| Carotenoid oxygenase [Mycobacterium gilvum PYR-GCK]
Length=512

 Score =  781 bits (2016),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 372/504 (74%), Positives = 427/504 (85%), Gaps = 6/504 (1%)

Query  5    IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPA  64
            +VGK+LSTLPEDDDHPYRTGPWRPQTTEWD DDL  V G++P DLDG+YLRNTENPLHPA
Sbjct  9    VVGKFLSTLPEDDDHPYRTGPWRPQTTEWDDDDLRVVEGQIPGDLDGVYLRNTENPLHPA  68

Query  65   FATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREH  124
               YHPFDGDGM+H+VGFRDGKAFYRNRF+RTD   AENEAGGPLWPG+AEP++LAKR++
Sbjct  69   LKYYHPFDGDGMLHMVGFRDGKAFYRNRFVRTDALAAENEAGGPLWPGIAEPIELAKRDY  128

Query  125  GWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVS  184
            GWGAR LMKDASSTDVIVHRG+ALTS YQCGDLYRIDP +   LGKE W+G FP DWGVS
Sbjct  129  GWGARTLMKDASSTDVIVHRGVALTSHYQCGDLYRIDPCTGADLGKEDWNGGFPTDWGVS  188

Query  185  AHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVI  244
            AHPKVD++TGELLFFNYSKQ P+MRYGVV    ++VH VDVPLPGPRLPHDMAFTENYVI
Sbjct  189  AHPKVDDRTGELLFFNYSKQAPFMRYGVVSPAGDVVHNVDVPLPGPRLPHDMAFTENYVI  248

Query  245  LNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYE  302
            LNDFPLFWD  LLE ++HLPRF+ ++PSRFAV+ RRG+   I WFEADPT+VLHF NA+E
Sbjct  249  LNDFPLFWDTGLLEHNIHLPRFHRDVPSRFAVLPRRGDTSQIMWFEADPTYVLHFPNAFE  308

Query  303  QGDEIVLDGFYEGDPQP---LDTGGT-KWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
             GDEIVLDGF++GDP+P   +D G + KW+++FR L+LD +Q+RLHRWR N+ TGAV EE
Sbjct  309  DGDEIVLDGFFQGDPEPTQGVDNGMSRKWQQIFRSLSLDGMQTRLHRWRFNLKTGAVREE  368

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYG  418
             LS+S TEFG IN  ++   +RYTYA TGKP WFLFDGLVKHDL TG  + ++F DGV+G
Sbjct  369  HLSDSFTEFGMINPGFSGRPHRYTYAETGKPGWFLFDGLVKHDLHTGTEQRFTFDDGVFG  428

Query  419  SETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
            SETAMAPRVG + EDDGYLVTLTTDMN DASYCLVFDAAR GDGP+CKL LPERISSGTH
Sbjct  429  SETAMAPRVGGTDEDDGYLVTLTTDMNTDASYCLVFDAARVGDGPVCKLQLPERISSGTH  488

Query  479  SAWVPGAELRRWDHAESPAAAVGL  502
            S W  G +L RW  +ES A A+GL
Sbjct  489  STWAAGCDLPRWRDSESAAGAIGL  512


>gi|126435697|ref|YP_001071388.1| carotenoid oxygenase [Mycobacterium sp. JLS]
 gi|126235497|gb|ABN98897.1| Carotenoid oxygenase [Mycobacterium sp. JLS]
Length=496

 Score =  732 bits (1890),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 352/493 (72%), Positives = 398/493 (81%), Gaps = 4/493 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M +  +  + STLP DDDHPYRTGPWRPQ TEW ADDL  V GEVPADLDG+YLRNTENP
Sbjct  1    MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPA   YHPFDGDGMIH+V F  GKA YRNRF+RTDGFLAENEAGGPLW G  E    A
Sbjct  61   LHPAATAYHPFDGDGMIHIVEFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR  GWGAR  MKDASSTDV+VHRG ALTSFY CGDLY++DPY+A+TLGKE+WHG FP D
Sbjct  121  KRTDGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQVDPYTADTLGKETWHGDFP-D  179

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPKVD  TGELLFF+YSK+ P++RYGVVD++  LVH+ DV LPGPR+PHDMAFTE
Sbjct  180  WGVSAHPKVDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTE  239

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NYVILNDFPLFW+P LL++D+H P F+ ++PSRFAV+ RRG+   +RWFE DPT+ LHF 
Sbjct  240  NYVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFV  299

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGGTKWE-KLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE GDEIVLDGF++ +P P   G    E   FR+LALD  +S LHRWR N+ TGA  E
Sbjct  300  NAYEDGDEIVLDGFFQDNPSPSTKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATE  359

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            E+LS+S+TEFG +N DY    +RY YAATGKP WFLFDGLVKHDL  G  E  +FGDGV+
Sbjct  360  ERLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLVKHDLRDGTEERITFGDGVF  419

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSETAMAPR   +AEDDGYLVTLTTDMNDDASYCLVFDAAR  DGP+CKL LPERI SGT
Sbjct  420  GSETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGT  479

Query  478  HSAWVPGAELRRW  490
            HS WV GAELRRW
Sbjct  480  HSTWVSGAELRRW  492


>gi|108800064|ref|YP_640261.1| carotenoid oxygenase [Mycobacterium sp. MCS]
 gi|119869190|ref|YP_939142.1| carotenoid oxygenase [Mycobacterium sp. KMS]
 gi|108770483|gb|ABG09205.1| Carotenoid oxygenase [Mycobacterium sp. MCS]
 gi|119695279|gb|ABL92352.1| Carotenoid oxygenase [Mycobacterium sp. KMS]
Length=496

 Score =  732 bits (1889),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 351/493 (72%), Positives = 398/493 (81%), Gaps = 4/493 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M +  +  + STLP DDDHPYRTGPWRPQ TEW ADDL  V GEVPADLDG+YLRNTENP
Sbjct  1    MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPA   YHPFDGDGMIH+V F  GKA YRNRF+RTDGFLAENEAGGPLW G  E    A
Sbjct  61   LHPAATAYHPFDGDGMIHIVEFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAA  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            KR  GWGAR  MKDASSTDV+VHRG ALTSFY CGDLY++DPY+A+TLGKE+WHG FP D
Sbjct  121  KRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQVDPYTADTLGKETWHGDFP-D  179

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPK+D  TGELLFF+YSK+ P++RYGVVD++  LVH+ DV LPGPR+PHDMAFTE
Sbjct  180  WGVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTE  239

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFT  298
            NYVILNDFPLFW+P LL++D+H P F+ ++PSRFAV+ RRG+   +RWFE DPT+ LHF 
Sbjct  240  NYVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFV  299

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTGGTKWE-KLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE GDEIVLDGF++ +P P   G    E   FR+LALD  +S LHRWR N+ TGA  E
Sbjct  300  NAYEDGDEIVLDGFFQDNPSPSTKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATE  359

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            E+LS+S+TEFG +N DY    +RY YAATGKP WFLFDGLVKHDL  G  E  +FGDGV+
Sbjct  360  ERLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLVKHDLRDGTEERITFGDGVF  419

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSETAMAPR   +AEDDGYLVTLTTDMNDDASYCLVFDAAR  DGP+CKL LPERI SGT
Sbjct  420  GSETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGT  479

Query  478  HSAWVPGAELRRW  490
            HS WV GAELRRW
Sbjct  480  HSTWVSGAELRRW  492


>gi|311741924|ref|ZP_07715735.1| dioxygenase [Aeromicrobium marinum DSM 15272]
 gi|311314930|gb|EFQ84836.1| dioxygenase [Aeromicrobium marinum DSM 15272]
Length=505

 Score =  731 bits (1887),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 346/505 (69%), Positives = 404/505 (80%), Gaps = 3/505 (0%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            MD+ +VG+ LSTLP DDDHPYRTGPW+PQTTEW+A++L  V GE+PADLDG+YLRNTENP
Sbjct  1    MDLDVVGRLLSTLPADDDHPYRTGPWQPQTTEWNAENLDVVQGEIPADLDGVYLRNTENP  60

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            LHPA   YHPFDGDGM+HVVGFRDG AFYRNRF+RTDG   E +AG  LW GLAE    +
Sbjct  61   LHPAIQNYHPFDGDGMVHVVGFRDGTAFYRNRFVRTDGLAMEADAGHALWAGLAERPSQS  120

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
              +HGWGAR  MKDASSTDVIVH G+ALTSFYQCGDLYR+DP +A TLGKE+W+G FPFD
Sbjct  121  LMDHGWGARTRMKDASSTDVIVHNGVALTSFYQCGDLYRVDPLTAETLGKETWNGAFPFD  180

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
            WGVSAHPK+D+ TGE+LFFNYS + PYM YGVVD   ELVHY  VPLPGPRLPHDMAFTE
Sbjct  181  WGVSAHPKIDDATGEMLFFNYSTEAPYMNYGVVDAAGELVHYTPVPLPGPRLPHDMAFTE  240

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFT  298
            NY ILND PLFWDP  L    +  RF+ ++P R  V+ RRG  +DIRWF+A+ TFVLH+ 
Sbjct  241  NYAILNDCPLFWDPEGLANGAYAARFHRDMPMRLGVIPRRGGPDDIRWFDAESTFVLHWV  300

Query  299  NAYEQGDEIVLDGFYEGDPQPLDTG-GTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE  357
            NAYE GDEIVLDGF+E DP P D G G KW++ FRFLA DR+Q RLHRWRLN+VTG+V E
Sbjct  301  NAYEDGDEIVLDGFFESDPSPADNGMGDKWQRAFRFLANDRMQPRLHRWRLNLVTGSVRE  360

Query  358  EQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVY  417
            E L+++ITEFG IN  +    +RY +AAT KP+WFLFDG+VKHD  TG  + + + +GVY
Sbjct  361  ESLTDTITEFGMINGSHGGRKHRYAWAATSKPAWFLFDGIVKHDTWTGQEQHFRYPEGVY  420

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            GSE+AMAPRVGS+AEDDGYL+TLTTDMN DAS+CLVFDA+    GP+C L LPERISSGT
Sbjct  421  GSESAMAPRVGSTAEDDGYLITLTTDMNADASFCLVFDASDITAGPVCTLRLPERISSGT  480

Query  478  HSAWVPGAELRRWDHAESPAAAVGL  502
            HS W PG +L  W  A+ PA AVGL
Sbjct  481  HSTWAPGHDLPTWATADDPATAVGL  505


>gi|103486497|ref|YP_616058.1| carotenoid oxygenase [Sphingopyxis alaskensis RB2256]
 gi|98976574|gb|ABF52725.1| Carotenoid oxygenase [Sphingopyxis alaskensis RB2256]
Length=498

 Score =  518 bits (1334),  Expect = 8e-145, Method: Compositional matrix adjust.
 Identities = 252/494 (52%), Positives = 330/494 (67%), Gaps = 13/494 (2%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDA---DDLTTVTGEVPADLDGIYLRNT  57
            M   +V    STL + +DHPY  G WRP   EW+A   +    V G +P D+DG+Y+R  
Sbjct  1    MTAQLVETIQSTL-QPNDHPYMQGAWRPTYNEWNAIFSNGDAEVIGTIPDDIDGVYVRTG  59

Query  58   ENPLHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPV  117
            EN +H     YHPFDGDG IH + F+ G+A YR+RF+RT GF AE EAG  LW GL EP 
Sbjct  60   ENQIHEPIGRYHPFDGDGFIHAISFKGGRASYRSRFVRTKGFAAEKEAGRSLWAGLMEPP  119

Query  118  QLAKREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRF  177
              + R  GWGA+  +KD+SSTDV +H G  +++FYQCG+ YR+DP++    G ESW    
Sbjct  120  HKSTRP-GWGAQEWLKDSSSTDVAIHAGKIISTFYQCGEAYRLDPFTLEQFGTESW---V  175

Query  178  PFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMA  237
            P D G+SAH KVD  TGEL+FFNYSK  PYM YGVV  +N+L HY+ VPLPGPRLPHDMA
Sbjct  176  PLD-GISAHCKVDLATGELMFFNYSKHAPYMHYGVVGADNKLKHYIPVPLPGPRLPHDMA  234

Query  238  FTENYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVL  295
            FTE+Y ILND PL+W+  LL++++H+ +F+P+  +RFA++ R G   DIRWFEA+PT+ L
Sbjct  235  FTEHYTILNDMPLYWNEELLKKNLHVVQFHPDQKTRFAIIPRHGQPEDIRWFEAEPTYTL  294

Query  296  HFTNAYEQGDEIVLDGFYEGDPQPLD--TGGTKWEKLFRFLALDRLQSRLHRWRLNMVTG  353
            H+ NA+E+GDEI+LDG+Y+ +P P          E++  +L    L+ RLHRWR N+ TG
Sbjct  295  HWLNAWEEGDEIILDGYYQEEPMPKSYPNAPEGLERMMAYLDQGLLKPRLHRWRFNLKTG  354

Query  354  AVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFG  413
            A  EE+L +   EFG  N  YA   YRY Y+A  +P WFLF G+VKHDL +   E Y FG
Sbjct  355  ATVEERLDDRDLEFGMFNHRYAGKPYRYAYSAIPEPGWFLFRGIVKHDLDSRTSEAYEFG  414

Query  414  DGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERI  473
             G +GSE   APR+G+  EDDGYLV+   D+  D S C++ DA     GP+C++ LPERI
Sbjct  415  RGRFGSEAPFAPRIGARDEDDGYLVSFIADLETDQSECVLIDAKNITAGPVCRIILPERI  474

Query  474  SSGTHSAWVPGAEL  487
             SGTHS W  G ++
Sbjct  475  CSGTHSVWASGNDI  488


>gi|85373333|ref|YP_457395.1| hypothetical protein ELI_02530 [Erythrobacter litoralis HTCC2594]
 gi|84786416|gb|ABC62598.1| hypothetical protein ELI_02530 [Erythrobacter litoralis HTCC2594]
Length=506

 Score =  511 bits (1317),  Expect = 9e-143, Method: Compositional matrix adjust.
 Identities = 255/487 (53%), Positives = 324/487 (67%), Gaps = 15/487 (3%)

Query  10   LSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYH  69
            + T  E  +HPY +G W P   E D D L  + GE+PAD+DGIYLRNTEN +H     +H
Sbjct  13   VRTTLEPSNHPYLSGAWTPLHEEVDVDALDVIEGEIPADIDGIYLRNTENQVHQPLGRHH  72

Query  70   PFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGAR  129
            PFDGD MIH VG   G A YRNRF+RT  F AE  AG  LW GL +P   ++R  G+GA 
Sbjct  73   PFDGDAMIHQVGISGGMASYRNRFVRTQCFEAEQVAGRSLWGGLMDPAGTSERP-GFGAH  131

Query  130  GLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKV  189
            G +KD  STD+IVH G+A  + YQCG+ + +DP +   LGK  W    P D G+SAHPKV
Sbjct  132  GGLKDTGSTDIIVHAGVAYATLYQCGEAWMLDPETLENLGKAPWG---PLD-GISAHPKV  187

Query  190  DNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFP  249
            D  TGEL+FFNYSK  PYM YGVVD+   L HYV VPLPGPRLPHDMA T+N+ ILND P
Sbjct  188  DEATGELMFFNYSKHAPYMHYGVVDRAGRLAHYVPVPLPGPRLPHDMAITKNWSILNDMP  247

Query  250  LFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQ----  303
            LFWD  LL+RD+H  R +  +P+RFA++ R G   DIRWFEA+PTFVLH+TNA+E+    
Sbjct  248  LFWDEDLLQRDIHAARLHEGLPTRFALIPRHGGPEDIRWFEAEPTFVLHWTNAWEETAED  307

Query  304  -GDEIVLDGFYEGDP--QPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL  360
               E+VL+G+++ +P  QPL+  G ++  +  ++     + RLHRWR N+ TG   EE+L
Sbjct  308  GSVEVVLEGYHQSNPMPQPLEEFG-QYAHMMAYVDEHSFECRLHRWRFNLATGETREERL  366

Query  361  SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE  420
            +E I EFGTIN  +A    RY ++ T KP WFLF+G V+HD  TG  + Y   +GVY SE
Sbjct  367  NERIVEFGTINPRFAMRPSRYVWSTTTKPGWFLFNGYVRHDTQTGEEQVYELPEGVYASE  426

Query  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480
            + M PR G + EDDGYLVTL  D N  +S C + DA+    GPIC+LALP +I SGTHS 
Sbjct  427  SPMVPRQGGTDEDDGYLVTLLIDENSGSSECAILDASDITKGPICRLALPHKICSGTHST  486

Query  481  WVPGAEL  487
            WV  ++L
Sbjct  487  WVERSQL  493


>gi|223940951|emb|CAQ43086.1| hypothetical protein [Chondromyces crocatus]
Length=490

 Score =  509 bits (1312),  Expect = 3e-142, Method: Compositional matrix adjust.
 Identities = 251/487 (52%), Positives = 326/487 (67%), Gaps = 5/487 (1%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M + IV +Y S LP +D HPYRTG WRP T E DA DL  V GE+PADL+G+YLRNTENP
Sbjct  1    MRVEIVKQYTSRLPAEDPHPYRTGAWRPNTVEVDAYDLDVVAGEIPADLEGVYLRNTENP  60

Query  61   LHPAF-ATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQL  119
            L  A    YHPFDGDGM+H + F  GKA YRNRF++T+G LAE EAG  LW G+ E   L
Sbjct  61   LFDALTGRYHPFDGDGMLHAIRFEGGKADYRNRFVKTEGLLAELEAGETLWAGILEAPAL  120

Query  120  AKREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHG-RFP  178
            +KR+ GWGAR  MKDASSTDV+VH G+AL++FYQCG+ Y++D  +    G  + H   FP
Sbjct  121  SKRD-GWGARTRMKDASSTDVLVHHGVALSTFYQCGEAYQLDLETLAPRGTANLHHPSFP  179

Query  179  FDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAF  238
                +SAHPKVD  TGELLFFNY+ + PY   G+ D    L   + VPLPGPRLPHDMAF
Sbjct  180  KGATISAHPKVDEATGELLFFNYAAEAPYCHVGIADAGGTLARVIPVPLPGPRLPHDMAF  239

Query  239  TENYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGND-IRWFEADPTFVLHF  297
            TE + I+ DFPLFWDP  L +  +  R++P++ +RFA+V R G   IRWF A PT+VLHF
Sbjct  240  TERFAIIGDFPLFWDPAKLAQGSYRARYFPDLGTRFALVPRDGQGAIRWFMASPTYVLHF  299

Query  298  TNAYEQGDEIVLDGFYEGDPQPLDT-GGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVH  356
            +NAYE+GD ++L+G+++G P P  T   T      + L +  +++R HRWR ++ TG   
Sbjct  300  SNAYEEGDAVILEGYHQGAPIPERTPDDTPISTFMKSLDMHAMKTRRHRWRFDLTTGETK  359

Query  357  EEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGV  416
            E  + +  +EF TI+  Y    +RY YAA G+P +FLF GL++ D+ TG    + F  GV
Sbjct  360  EAPVDDECSEFPTIHQGYGGKKHRYVYAAVGEPGFFLFSGLLRTDVETGAKAIHRFPKGV  419

Query  417  YGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSG  476
            + SE    PR G++ EDDGY+VT TTD+ +D S C +FDA     GPI ++ LP RISSG
Sbjct  420  FASEAPFCPRKGATEEDDGYVVTFTTDVVNDVSECQIFDARGIERGPIARVRLPMRISSG  479

Query  477  THSAWVP  483
            TH+ W P
Sbjct  480  THATWAP  486


>gi|167645237|ref|YP_001682900.1| carotenoid oxygenase [Caulobacter sp. K31]
 gi|167347667|gb|ABZ70402.1| Carotenoid oxygenase [Caulobacter sp. K31]
Length=487

 Score =  509 bits (1310),  Expect = 6e-142, Method: Compositional matrix adjust.
 Identities = 255/467 (55%), Positives = 309/467 (67%), Gaps = 9/467 (1%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            +HPY TG W P   E DA DL  + G +PADLDG+YLRNTENP+H     YHPFDGDGM+
Sbjct  17   NHPYMTGAWTPLHEEVDAVDLEVLEGAIPADLDGVYLRNTENPVHQPLGRYHPFDGDGMV  76

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
            H + F++G A YRNRFIRT GF AE EAG  LW GLA+    ++R  G+GA G +KD +S
Sbjct  77   HQIEFKNGAASYRNRFIRTRGFEAEQEAGESLWGGLADGPGTSRRP-GFGAHGGLKDTAS  135

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TD++VH G A+ +FYQCG+ YR+DP +   LG  +W    P D GVSAH KVD  TGELL
Sbjct  136  TDIVVHAGEAIATFYQCGEAYRLDPLTLENLGVAAW---APLD-GVSAHAKVDEATGELL  191

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            FFNYSK  PYM YGVVD N +   Y  + LPGPRLPHDMAFT NY ILND P+FWD  LL
Sbjct  192  FFNYSKHAPYMHYGVVDANGKRTVYQPIDLPGPRLPHDMAFTANYSILNDLPVFWDQTLL  251

Query  258  ERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGD-  316
            ERD+H  R +  +PSRF +V R G ++RWFEA PT+VLH+ NAYE GDEIVLDG+++ + 
Sbjct  252  ERDIHAVRLHKGVPSRFGIVPRHGGEVRWFEAAPTYVLHWLNAYEDGDEIVLDGYFQENP  311

Query  317  -PQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYA  375
             P+PL+        L  +L     + +LHRWR N+ TG   E+ L E I EFG  N  YA
Sbjct  312  TPRPLEDAPEGHGHLMAYLDEHSFRPKLHRWRFNLATGETTEQHLDERILEFGMFNQAYA  371

Query  376  ASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDG  435
               YRY Y+ T KP WFLF+G VKHDL TG     +   G Y SE   APRVG+  EDDG
Sbjct  372  GRPYRYAYSTTAKPGWFLFNGFVKHDLETGESWSLALEPGRYASEAPFAPRVGAVDEDDG  431

Query  436  YLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            YLV+   D N   S CLV DA      P C++ALP +ISSGTH+ W 
Sbjct  432  YLVSFIIDENRGTSECLVVDAKT--MTPTCRIALPHKISSGTHAVWA  476


>gi|85707934|ref|ZP_01039000.1| hypothetical protein NAP1_01825 [Erythrobacter sp. NAP1]
 gi|85689468|gb|EAQ29471.1| hypothetical protein NAP1_01825 [Erythrobacter sp. NAP1]
Length=537

 Score =  507 bits (1305),  Expect = 2e-141, Method: Compositional matrix adjust.
 Identities = 251/486 (52%), Positives = 317/486 (66%), Gaps = 14/486 (2%)

Query  10   LSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYH  69
            + T  E  +HPY +GPW P   E D D+L  + G +P D+DGIYLRNTENP+H     +H
Sbjct  45   VKTSLEPSNHPYLSGPWTPCHEEVDVDELEVIEGAIPDDIDGIYLRNTENPVHQPLGRHH  104

Query  70   PFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGAR  129
            PFDGD M+H V    GKA YRNRFIRT  F  E  AG  LW GL +P   + R  G+GA 
Sbjct  105  PFDGDAMVHQVSISGGKASYRNRFIRTHCFTEEQIAGKSLWGGLMDPHGTSARP-GYGAH  163

Query  130  GLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKV  189
              +KD  STD+IVH G A  +FYQCG+ + +DP +    GK  W    P D GVSAHPKV
Sbjct  164  EGLKDTGSTDIIVHAGTAYATFYQCGEAWMLDPVTLANKGKAPWG---PVD-GVSAHPKV  219

Query  190  DNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFP  249
            D  TGE++FFNYSK  PYM YGVVD+   L HYV +PLPGPRLPHDMA T+N+ ILND P
Sbjct  220  DEATGEMMFFNYSKYAPYMHYGVVDREGNLAHYVPIPLPGPRLPHDMAITKNWSILNDMP  279

Query  250  LFWDPRLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYE----Q  303
            LFWD  LLER++H  R +  +P+RFA++ R G   DIRWFEA PT+VLH+TNAYE     
Sbjct  280  LFWDANLLERNIHAARIHEGVPTRFALIPRHGAPEDIRWFEASPTYVLHWTNAYEVSGSD  339

Query  304  GDEIVLDGFYEGDPQP--LDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLS  361
            GDE+VL+G+Y+  P P  ++  G ++  +  ++     QSRLHRWR N+ TG   EE+LS
Sbjct  340  GDEVVLEGYYQDKPMPDPIEEAG-EYSHMMAYVDEHSFQSRLHRWRFNLKTGETTEERLS  398

Query  362  ESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSET  421
            + I EFG IN DY     RY ++ T +P WFLF+G V+HD  TG  + Y   +GVY SE+
Sbjct  399  DRIVEFGMINPDYLMQKSRYIWSTTTRPGWFLFNGYVRHDTETGGEQVYQLPEGVYASES  458

Query  422  AMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAW  481
             M PR G+S+EDDGYLVT   D N   S   + DA+    GPIC+ ALP +ISSG H+ W
Sbjct  459  PMVPRKGASSEDDGYLVTFLIDENTGTSQLAILDASDIAKGPICRAALPHKISSGVHTCW  518

Query  482  VPGAEL  487
            V  ++L
Sbjct  519  VEHSQL  524


>gi|16125029|ref|NP_419593.1| hypothetical protein CC_0776 [Caulobacter crescentus CB15]
 gi|221233752|ref|YP_002516188.1| lignostilbene-alpha,beta-dioxygenase [Caulobacter crescentus 
NA1000]
 gi|13422015|gb|AAK22761.1| conserved hypothetical protein [Caulobacter crescentus CB15]
 gi|220962924|gb|ACL94280.1| lignostilbene-alpha,beta-dioxygenase [Caulobacter crescentus 
NA1000]
Length=483

 Score =  495 bits (1274),  Expect = 9e-138, Method: Compositional matrix adjust.
 Identities = 246/467 (53%), Positives = 309/467 (67%), Gaps = 9/467 (1%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            +HPY TGPW PQ  E +A DL  + G +PADLDG+YLRNTENP+H     YHPFDGDGMI
Sbjct  17   NHPYMTGPWTPQHEEVNAWDLEVLEGAIPADLDGVYLRNTENPVHDPIGRYHPFDGDGMI  76

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
            H + F+ G A YRNRF+RT  F AE E    LW GL +   ++KR  G+GA G +KD++S
Sbjct  77   HQIEFKGGAATYRNRFVRTRCFEAEQEVNEGLWGGLMDGPGVSKRP-GFGAHGALKDSAS  135

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TD++VH G A+ +FYQCG+ YR+DP +   LG  SW    P + GVSAHPKVD  TGEL+
Sbjct  136  TDIVVHNGEAIATFYQCGEAYRLDPLTLENLGVASWA---PLE-GVSAHPKVDEATGELM  191

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            FFNYSK  PYM YGVV  + +   Y  VPLPGPRLPHDMAF+  Y ILND P+FWD  L+
Sbjct  192  FFNYSKAWPYMHYGVVGPDGKRKVYQGVPLPGPRLPHDMAFSSKYAILNDLPVFWDQELM  251

Query  258  ERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGD-  316
             RD+H  R +  IPSRFA+V R G + RWFEA+PT+VLH+ NAYE GDE+VLDG+++   
Sbjct  252  ARDIHAVRLHKGIPSRFALVPREGGEPRWFEAEPTYVLHWLNAYEDGDEVVLDGYFQEKP  311

Query  317  -PQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYA  375
             P+PL+        L  +L       +LHRWR N+ TG   E+ L + + EFG  N  YA
Sbjct  312  IPRPLEGAPDGHGHLMAYLDEHSFLPKLHRWRFNLKTGETTEKHLDDRVLEFGMFNQKYA  371

Query  376  ASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDG  435
               YRY Y+ T KP WFLF+G VKHDL TG     +  +G Y SE   AP+VG+  EDDG
Sbjct  372  GKPYRYAYSTTAKPGWFLFNGFVKHDLETGESWSIALPEGRYASEAPFAPKVGAVDEDDG  431

Query  436  YLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            YLV+   D N  AS CL+ DA R     +C++ALP ++SSGTH+ W 
Sbjct  432  YLVSFIIDENKGASECLIVDAKR--FEVVCRIALPHKLSSGTHTVWA  476


>gi|295690938|ref|YP_003594631.1| carotenoid oxygenase [Caulobacter segnis ATCC 21756]
 gi|295432841|gb|ADG12013.1| Carotenoid oxygenase [Caulobacter segnis ATCC 21756]
Length=483

 Score =  491 bits (1264),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 248/474 (53%), Positives = 312/474 (66%), Gaps = 10/474 (2%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            +HPY TG W PQ  E +A DL  + G +PADLDG+YLRNTENP+H     YHPFDGDGMI
Sbjct  17   NHPYMTGAWTPQHEEVNAWDLEVLEGAIPADLDGVYLRNTENPVHDPLGRYHPFDGDGMI  76

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
            H + FR+G+A YRNRF+RT  F AE E    LW GL +    +KR  G+GA G +KD++S
Sbjct  77   HQIEFRNGQATYRNRFVRTRCFEAEQEVNESLWGGLMDGPGTSKRP-GFGAHGSLKDSAS  135

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TD++VH G A+ +FYQCG+ YR+DP +  TLG  SW    P D GVSAHPKVD  TGEL+
Sbjct  136  TDIVVHNGEAIATFYQCGEAYRLDPLTLETLGVASW---APLD-GVSAHPKVDEATGELM  191

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            FFNYSK  PYM YGVV  + +   Y  VPLPGPRLPHDM F+E++ ILND P+FWD  L+
Sbjct  192  FFNYSKAWPYMHYGVVGPDGKRSLYQGVPLPGPRLPHDMCFSEHWAILNDLPVFWDQELM  251

Query  258  ERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGD-  316
             RD+H  R +  +PSRFA+V R G + RWFEA+PT+VLH+ NAYE GDE+VLDG+++   
Sbjct  252  ARDIHAVRLHKGLPSRFALVPRHGGEPRWFEAEPTYVLHWLNAYEDGDEVVLDGYFQEKP  311

Query  317  -PQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYA  375
             P+PL+        L  +L       +LHRWR N+ TG   E+ L + I EFG  N  YA
Sbjct  312  IPRPLEGAPDGHGHLMAYLDEHSFLPKLHRWRFNLKTGETTEKHLDDRILEFGMFNQKYA  371

Query  376  ASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDG  435
               YRY Y+ T KP WFLF+G VKHDL TG     +  +G Y SE   AP+VG+  EDDG
Sbjct  372  GKPYRYAYSTTAKPGWFLFNGFVKHDLETGESWSITLPEGRYASEAPFAPKVGAVDEDDG  431

Query  436  YLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAELRR  489
            YLV+   D N   S C + DA       +C++ALP ++SSGTHS W  G E+ R
Sbjct  432  YLVSFIIDENRGTSECAIIDAR--AFEVVCRVALPHKLSSGTHSVWA-GREMLR  482


>gi|221065802|ref|ZP_03541907.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
 gi|220710825|gb|EED66193.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
Length=489

 Score =  481 bits (1238),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 251/495 (51%), Positives = 326/495 (66%), Gaps = 18/495 (3%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M   IVG+   T+   D++ + +GP+ P   E+ A +L  V GEVP  L+G+YLRNT+NP
Sbjct  1    MHTEIVGRIRPTITNWDNN-FMSGPFTPNFVEYTATELE-VIGEVPRRLNGVYLRNTQNP  58

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            +H     +H FDGDGM+H++ FR+G+  YRNRF+RT GF  E  AG  L+ GL +   LA
Sbjct  59   VHEPRGVHHAFDGDGMLHLLSFRNGQVQYRNRFLRTKGFEEEQAAGHALYAGLIDNPGLA  118

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            +R  GWGARG +KD S+TDVIVH G ALT+FYQCG+ YR D  +   LG  +W  +   D
Sbjct  119  QRP-GWGARGGLKDTSATDVIVHAGSALTTFYQCGEPYRFDARTLEPLGVSAWAAQVLKD  177

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
             G+SAHPKV   +G+LLFFNYSK+ PYM YG V+  +ELVHYV VPLPGPRLPHDM FTE
Sbjct  178  NGISAHPKVCPSSGDLLFFNYSKEAPYMHYGEVNARDELVHYVPVPLPGPRLPHDMMFTE  237

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARR---GNDIRWFEADPTFVLHF  297
            N+ ILNDFPL WD  LL +  H   ++ + PSRFAVV RR      ++WFEA PT+VLH+
Sbjct  238  NFAILNDFPLHWDESLLAQGKHKLSYFDQKPSRFAVVPRRHAPQTGVKWFEASPTYVLHW  297

Query  298  TNAYEQGDEIVLDGFYEGDPQPL----DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTG  353
             NA+E+GDEIVL G+++  P P     +TG T        L  DR    L+ WRLN+ TG
Sbjct  298  LNAWEEGDEIVLHGYHQQQPMPRAGYDNTGAT--------LGPDRYGPTLYEWRLNLRTG  349

Query  354  AVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFG  413
             V E +L +   EFG INA +    YRY+Y     P  FLFDG+ + D  TG  + Y FG
Sbjct  350  GVVERRLFDRHLEFGLINARHWGRPYRYSYNMIAHPEHFLFDGIQRFDHTTGETQEYRFG  409

Query  414  DGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERI  473
            +G +GSE+ MAP + +SAEDDGY+V+  TDMN D+S C+V DA+    GP+ ++ LP RI
Sbjct  410  EGRFGSESPMAPALDASAEDDGYVVSFVTDMNTDSSECVVLDASDLARGPVARIRLPHRI  469

Query  474  SSGTHSAWVPGAELR  488
            SSGTH+ W   +ELR
Sbjct  470  SSGTHACWADASELR  484


>gi|339328147|ref|YP_004687839.1| apocarotenoid-15,15'-oxygenase [Cupriavidus necator N-1]
 gi|338170748|gb|AEI81801.1| apocarotenoid-15,15'-oxygenase [Cupriavidus necator N-1]
Length=491

 Score =  477 bits (1227),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 243/495 (50%), Positives = 321/495 (65%), Gaps = 18/495 (3%)

Query  1    MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP  60
            M + +VG+   TL  +  HPY  GP+ P   E +A DL  V G +PA L+G+YLRNT+NP
Sbjct  1    MHVEVVGEIHPTLALEG-HPYTAGPFTPNYREVNAVDLE-VEGTIPARLNGVYLRNTQNP  58

Query  61   LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA  120
            +H     +HPFDGD M+H++ F++G+  YRNRF+RT  F  E +AG  L+ GL +   L+
Sbjct  59   VHQPLGKFHPFDGDAMLHLLSFQNGRCEYRNRFVRTKAFQQEQQAGRALYAGLIDKPSLS  118

Query  121  KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD  180
            +   GWGARG ++D+++TDVIVH G AL  FYQCG+ YR+D  +    G ++W      D
Sbjct  119  ELP-GWGARGGLRDSAATDVIVHAGKALAMFYQCGEPYRLDARTLELEGVDAWGADVLRD  177

Query  181  WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE  240
             G+SAH KVD +TG+LLFFNYSK  PYM YG VD+ N L HYV VPLPGPRLPHDMAFTE
Sbjct  178  CGLSAHAKVDPRTGDLLFFNYSKDAPYMHYGEVDRQNRLAHYVPVPLPGPRLPHDMAFTE  237

Query  241  NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRG---NDIRWFEADPTFVLHF  297
            ++ ILNDFPL WD  LL +  H   +YP+ PSRFA+V RRG     IRWFEA PT+VLH+
Sbjct  238  HFAILNDFPLHWDENLLPQGKHKLSYYPDKPSRFAIVPRRGAALAQIRWFEASPTYVLHW  297

Query  298  TNAYEQGDEIVLDGFYEGDPQPL----DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTG  353
             NA+E GDE+VL G+++  P P     +TG T        +  DR    L+ WR N+ TG
Sbjct  298  LNAWEDGDEVVLHGYHQKTPMPKAGYDNTGNT--------MGPDRYGPTLYEWRFNLRTG  349

Query  354  AVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFG  413
            A  E +L E   EFG +N +Y    YRY+Y     P  FLFDG++++D  TG  + Y FG
Sbjct  350  ATRERRLDERYLEFGMVNMEYWGKPYRYSYNMIAHPGAFLFDGILRYDHTTGESQQYLFG  409

Query  414  DGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERI  473
            +G +GSE+ MAP   +  EDDGY+V+  TDMN+D S CLV DA     GP+ ++ LP RI
Sbjct  410  EGRFGSESPMAPCHDAQGEDDGYVVSFVTDMNNDRSECLVLDARDLAAGPVARIFLPHRI  469

Query  474  SSGTHSAWVPGAELR  488
            SSGTH+ W    +++
Sbjct  470  SSGTHACWADARDIQ  484


>gi|221065485|ref|ZP_03541590.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
 gi|220710508|gb|EED65876.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
Length=505

 Score =  443 bits (1140),  Expect = 3e-122, Method: Compositional matrix adjust.
 Identities = 226/495 (46%), Positives = 307/495 (63%), Gaps = 17/495 (3%)

Query  5    IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTT-VTGEVPADLDGIYLRNTENPLHP  63
            I+  Y ST+  D+DHP+  GP+ P   EW AD  +  V GE+P DL GIY+RNT N +H 
Sbjct  4    ILHTYQSTITPDNDHPFLRGPFTPAMQEWVADTASMQVIGEIPRDLHGIYVRNTHNQVHE  63

Query  64   AFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKRE  123
            A   YHPFDGDGM+H + F +GKA YRNRF++T GFLAE  AG  LWPG+  P   A+R 
Sbjct  64   ALGIYHPFDGDGMLHAMHFEEGKATYRNRFVQTTGFLAEQAAGRSLWPGMLSPQMQARR-  122

Query  124  HGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGV  183
             GWG+ G MKD + TDV +H G  L S  Q  + +R+DP +  TLG ++   RF  D GV
Sbjct  123  -GWGSMGAMKDNAGTDVKIHAGKLLASMSQGSEPWRLDPVTLETLGPDADWARFVSD-GV  180

Query  184  SAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYV  243
            ++H KVD  TGE++FFNY ++ PYM YGVVD++N LVHYV + LPG R PHD+  T+NY 
Sbjct  181  ASHYKVDPATGEMMFFNYPEKPPYMNYGVVDRHNRLVHYVPIDLPGARWPHDLGITKNYT  240

Query  244  ILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAY  301
            IL+D P  +DP LL +     RFY + P+RF ++ R G+   +RWFE  P  +LH  N Y
Sbjct  241  ILHDLPFHFDPALLAKGERKMRFYGDRPARFGILPRHGDSASVRWFEGTPCHILHLANCY  300

Query  302  EQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRL---------HRWRLNMVT  352
            E G+E+++DG     P   + G +  E   R  A D++++ L         +RWR NM T
Sbjct  301  EVGNEVIMDGCIMPTPHKPNVGQSLAEG--RQAAYDKIRAHLDKHNNPTLMYRWRFNMKT  358

Query  353  GAVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSF  412
            G   EEQ+ + ITEF  ++ DY    YRY++    +   +LF GL ++D+LT   +   +
Sbjct  359  GETREEQIDDEITEFPMVSNDYVGRPYRYSFNVLYEKGEWLFRGLKRYDMLTSQTQTLEY  418

Query  413  GDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPER  472
            G G YGSE  MA R+G+ AEDDGY++T   +M D+ S C V  A     GP+ ++ LP R
Sbjct  419  GKGCYGSEPQMARRIGAVAEDDGYVLTFVNNMLDERSECWVIPAGDISRGPLARIVLPHR  478

Query  473  ISSGTHSAWVPGAEL  487
            IS+GTHSAWV G  +
Sbjct  479  ISAGTHSAWVEGDRI  493


>gi|329894155|ref|ZP_08270140.1| Carotenoid oxygenase [gamma proteobacterium IMCC3088]
 gi|328923327|gb|EGG30647.1| Carotenoid oxygenase [gamma proteobacterium IMCC3088]
Length=496

 Score =  400 bits (1028),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 208/493 (43%), Positives = 287/493 (59%), Gaps = 8/493 (1%)

Query  3    ITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDAD-DLTTVTGEVPADLDGIYLRNTENPL  61
            + I+ +   T+  D+D+P+  G ++P   E+DAD D   V G +P DL G+Y RNT N +
Sbjct  2    LKIINEEKITISPDNDNPFLQGLFKPNAREYDADTDTLEVIGTIPNDLWGVYARNTHNQV  61

Query  62   HPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAK  121
            H     YHPFDGDGMIH   F DGK  YRNRF+ T GFLAE  AG  LWPG+ EP + + 
Sbjct  62   HEPIGIYHPFDGDGMIHSAYFCDGKMQYRNRFVHTTGFLAEKAAGRALWPGVLEPERFSY  121

Query  122  REHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDW  181
            R  GWGA G MKD + TDVI H G  L +  Q  + +R+DP +   LG +    +     
Sbjct  122  R--GWGAMGAMKDNAGTDVIYHNGSLLVTMSQGSEPWRMDPVTLENLGPDPVLAKAVGYA  179

Query  182  GVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTEN  241
            G++   KVD +T E++F NY ++ P +  G VD N  L  Y  +    PR PHD+  TEN
Sbjct  180  GIAGEFKVDYRTNEMVFQNYPEEPPSINVGTVDSNGNLASYRSIKFDFPRWPHDLGMTEN  239

Query  242  YVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVAR--RGNDIRWFEADPTFVLHFTN  299
            Y+I++D PL++DP L ++     +FYP+ PSRF V +R  + +DI+WFEA   F+LH  N
Sbjct  240  YLIVHDLPLYFDPDLRKQGQRKLQFYPDKPSRFGVFSRSDQRSDIQWFEAKSCFILHTAN  299

Query  300  AYEQGDEIVLDGFYEGDPQPLDTGG---TKWEKLFRFLALDRLQSRLHRWRLNMVTGAVH  356
             YE+GDEI++DG    +PQ    G      +E++   L   R ++RL+RWR N+  G   
Sbjct  300  YYEEGDEIIMDGCVSFEPQGPGVGEHSENPYERIMAHLDKHRTKTRLYRWRFNLKNGTTI  359

Query  357  EEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGV  416
            E  + + I EF     D     YRY YA+  +   +  +G+ K DL TG H  Y +G+G 
Sbjct  360  EGFIDQEICEFPVCRNDCKGYPYRYIYASLFEAGTWNMNGIKKFDLQTGVHTRYEYGEGR  419

Query  417  YGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSG  476
            YG E   APR+ S  EDDGYL+    D+  D S   +FDA    +GP+C++ LPERI SG
Sbjct  420  YGGEVHFAPRINSQFEDDGYLIVFIQDLVLDRSEAAIFDAQALANGPLCQIILPERIQSG  479

Query  477  THSAWVPGAELRR  489
            TH+ WV G  L+R
Sbjct  480  THACWVEGERLKR  492


>gi|300788787|ref|YP_003769078.1| carotenoid cleavage dioxygenase [Amycolatopsis mediterranei U32]
 gi|299798301|gb|ADJ48676.1| carotenoid cleavage dioxygenase [Amycolatopsis mediterranei U32]
 gi|340530406|gb|AEK45611.1| carotenoid cleavage dioxygenase [Amycolatopsis mediterranei S699]
Length=490

 Score =  378 bits (971),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 216/482 (45%), Positives = 281/482 (59%), Gaps = 16/482 (3%)

Query  12   TLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPF  71
            T   D+ +PY  G + P  TE DA+DL  V GE+P DL+G+YLRN  NP       YH F
Sbjct  14   TADADEANPYLLGVYAPVGTEIDAEDLQ-VIGEIPKDLNGVYLRNGPNPRFAPEGRYHWF  72

Query  72   DGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAK--REHGWGAR  129
            DGDGMIH V   +GKA YRNR+IRT  F AE+ AG  LW G+ E  +       HG G  
Sbjct  73   DGDGMIHAVHLENGKARYRNRWIRTKAFEAESAAGKGLWTGVMENPKDNPFGNTHGLG--  130

Query  130  GLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKV  189
              +KD ++TDV+ HRG  L ++Y CG  Y +DP S  TLG E + G    D  + AHPKV
Sbjct  131  --LKDNANTDVVFHRGRILATWYLCGSPYAVDPLSLETLGAEDFLGTLAGD--MMAHPKV  186

Query  190  DNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFP  249
            D  TGEL +F+Y  + PY+RYGV+  + ++V   DV LPGPRLPHDMA TE+Y +L D P
Sbjct  187  DETTGELFWFDYGPRPPYLRYGVISADGKVVRTTDVELPGPRLPHDMAITEHYAVLMDLP  246

Query  250  LFWDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEI  307
            L  D    ++  H   F   +PSRF V+ R G+   +RWFEA P ++ H  NA+EQG E+
Sbjct  247  LVQDLAAAQQGRHKLHFDRSMPSRFGVLPRYGDGSQVRWFEASPCYIYHVVNAWEQGGEV  306

Query  308  VLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEF  367
            VLD      PQP     T   K+  +L   RL ++LHR+R ++ TGA HE  L +  TEF
Sbjct  307  VLDVCRVQRPQPRADAHTPLAKMLSYL---RLDAQLHRYRFDLRTGACHEAPLDDDNTEF  363

Query  368  GTINADYAASSYRYTYAATGKP-SWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPR  426
             T++A       RY+YA    P S   FDGLV+HD L G    Y FG G +GSE   APR
Sbjct  364  PTVDARGVGRRNRYSYAVHISPESTLKFDGLVRHDNLAGTKTEYRFGPGRWGSEAPFAPR  423

Query  427  VGSSAED-DGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGA  485
             G+  +  DGYLVT   D  +  S   +FDAA    GP+ ++ LP+R+  G H+ WV   
Sbjct  424  EGAPVDSADGYLVTFVQDEREGRSELDIFDAADLAAGPVARVLLPQRVPLGFHATWVRAD  483

Query  486  EL  487
            +L
Sbjct  484  QL  485


>gi|271963075|ref|YP_003337271.1| 9-cis-epoxycarotenoid dioxygenase [Streptosporangium roseum DSM 
43021]
 gi|270506250|gb|ACZ84528.1| 9-cis-epoxycarotenoid dioxygenase [Streptosporangium roseum DSM 
43021]
Length=483

 Score =  369 bits (946),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 206/475 (44%), Positives = 285/475 (60%), Gaps = 15/475 (3%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY  G + P   E  A++L  V GE+P DL+G+YLRN  N   PA   YH FDGDGM+H
Sbjct  15   NPYLMGVYAPVQDEITAENLKVV-GEIPKDLNGVYLRNGPNARFPAKGRYHWFDGDGMVH  73

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGL-MKDASS  137
             V F +G+A YRNR++RT  F AE+ AG  LW G+ E     K       RGL +KD+++
Sbjct  74   AVHFENGRARYRNRYVRTRAFEAESAAGRSLWTGVMEN---PKGNPFGNTRGLNLKDSAN  130

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TDVI HRG  LT++Y CG  Y +DP S   LG E++      D+   AHPK+D +TGEL 
Sbjct  131  TDVIFHRGKVLTTWYLCGAPYGMDPLSLEALGAETFLDTLTGDF--MAHPKLDERTGELF  188

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            +F+Y    PY+RYGVV     + H V+  LPG RLPHDMA T N+ IL D PL+ D    
Sbjct  189  WFDYGPGRPYLRYGVVGAGGRVEHCVEPDLPGARLPHDMAITANHAILMDLPLYQDMDAA  248

Query  258  ERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEG  315
             +  +   F  E+PSRF V+ RRG  ++IRWFEA+P ++ H  N++E+ DEIV+D     
Sbjct  249  RQGRYKLTFNRELPSRFGVIPRRGQAHEIRWFEAEPCYIYHVVNSWEESDEIVMDVCRVS  308

Query  316  DPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLS-ESITEFGTINADY  374
             P P  +G      L R ++  +L +R+HR+R ++ TG  HEE +  +  TEF +I+A  
Sbjct  309  RPAPAGSG----SPLARMISYLKLDARMHRYRFDLRTGRTHEESVDPDHNTEFPSIDARL  364

Query  375  AASSYRYTYAATGK-PSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAED  433
                 RY Y  + K  +  LFDGLV++D +TG  E YS+G+  YGSE   APR G++AE+
Sbjct  365  TGRRSRYAYNVSVKDAATNLFDGLVRYDNVTGAKETYSYGEHRYGSEAPFAPRDGATAEE  424

Query  434  DGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAELR  488
            DGYLV+  TD  +  S   V  AA    GP+ ++ LP+R+  G H+ WV   +L+
Sbjct  425  DGYLVSFVTDEREGTSEVQVLHAADLSAGPVARIILPQRVPLGFHATWVRADQLK  479


>gi|331699051|ref|YP_004335290.1| 9-cis-epoxycarotenoid dioxygenase [Pseudonocardia dioxanivorans 
CB1190]
 gi|326953740|gb|AEA27437.1| 9-cis-epoxycarotenoid dioxygenase [Pseudonocardia dioxanivorans 
CB1190]
Length=483

 Score =  365 bits (937),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 209/477 (44%), Positives = 282/477 (60%), Gaps = 15/477 (3%)

Query  17   DDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGM  76
            +D+PY  G + P   E  ADDL  V GE+P DL+G++LRN  N    A   YH FDGDGM
Sbjct  17   EDNPYLLGIFAPVRDEITADDLE-VIGEIPRDLNGVHLRNGPNRRFDAPGRYHWFDGDGM  75

Query  77   IHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWG-ARGL-MKD  134
            +H + F +G A YRNR++RT    AE  AG  LW G+ E    + R +  G ARGL  KD
Sbjct  76   VHAMAFENGTARYRNRWVRTRALAAEEAAGHALWSGVME----SPRGNPVGTARGLPFKD  131

Query  135  ASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTG  194
            +++TD+I HRG  L ++Y CG    +DP S  T+G E + G    D  V AHPKVD  TG
Sbjct  132  SANTDLIHHRGRVLATWYLCGQPMSMDPLSLETIGAEDFLGTLHGD--VMAHPKVDEHTG  189

Query  195  ELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDP  254
            EL++F+Y  ++P +RYGVV+    + H V++ LPGPRLPHDMA TEN+ IL D PL  DP
Sbjct  190  ELMWFDYGARDPLLRYGVVNAEGAIDHEVEIDLPGPRLPHDMAITENFSILMDLPLTQDP  249

Query  255  RLLERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGF  312
                R  +   F    PSRFAVV RRG  +++RWFEA+P ++ H  NA+E    IV+D  
Sbjct  250  AAARRGRYKIGFDRSTPSRFAVVPRRGAASEVRWFEAEPCYIYHVVNAWEDARTIVMDVC  309

Query  313  YEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINA  372
                P+P+ T      KL  +L   RL +RLHR+  ++ +G   E QL ++ TEF +I+A
Sbjct  310  RVTRPEPVPTRPGPLGKLLGYL---RLDARLHRYVFDLDSGTTTESQLDDANTEFPSIDA  366

Query  373  DYAASSYRYTYAA-TGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSA  431
                   RY Y           FDGL+++D +TG  + + FG G +GSE   APR GS+ 
Sbjct  367  RACGRPTRYAYNVHIADAETVRFDGLLRYDRVTGERQHHWFGPGRFGSEAPFAPRDGSTG  426

Query  432  EDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAELR  488
            EDDGYLVT  TD  DD S   + DA+    GP+ ++ LP+R+  G H+ WV   +LR
Sbjct  427  EDDGYLVTFVTDERDDRSEVQILDASDLAAGPVARVLLPQRVPLGFHATWVRADQLR  483


>gi|254482257|ref|ZP_05095498.1| Retinal pigment epithelial membrane protein [marine gamma proteobacterium 
HTCC2148]
 gi|214037582|gb|EEB78248.1| Retinal pigment epithelial membrane protein [marine gamma proteobacterium 
HTCC2148]
Length=507

 Score =  343 bits (880),  Expect = 4e-92, Method: Compositional matrix adjust.
 Identities = 198/483 (41%), Positives = 270/483 (56%), Gaps = 22/483 (4%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            D+PY  G + P T E   D L  V GE+PADL G Y RN  NP+  +   +HPFDGDGM+
Sbjct  34   DNPYLHGLYAPTTEELSVDGLEVV-GELPADLVGGYFRNGPNPVFESKNRHHPFDGDGMV  92

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
              V F+DGK  YRNR++ T  F  E   G  + PG+  P   +  + G      +KD S+
Sbjct  93   RGVYFKDGKVSYRNRWVETSAFGGEAADGKSVSPGVMGPFDYSISQFG------IKDTSN  146

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TDV+ + G  +T +Y  G  YR+D  +  T G     GR      +SAH KVD  TGEL+
Sbjct  147  TDVLWYNGDIMTLWYNAGHPYRLDSQTLETKGHYQLEGREQLR--LSAHSKVDWSTGELM  204

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            FF+Y  + PYM +GV D N  L H V + LPGPRLPHD+ FT NY +L+D P F D  +L
Sbjct  205  FFDYGDELPYMTFGVADANGRLQHEVPIELPGPRLPHDIGFTTNYAVLHDLPFFHDMEVL  264

Query  258  ERDVH-LPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYE  314
             R    +  F+ +IP+RF ++ RRG  ++IRWFE  P ++LH TN +E+G+ +V+DG   
Sbjct  265  RRHKQRVLTFHQDIPTRFGIIPRRGQSDEIRWFECQPCYILHVTNCWEEGEWVVMDGCRS  324

Query  315  GDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADY  374
             +P P    G    +L   LA  RL++  +RWR N+ TG V E  +    TEF   N  +
Sbjct  325  LNPMPDSQPGEG--ELAHMLAYMRLEANAYRWRFNLRTGEVKEGDIDLLNTEFNKSNPIF  382

Query  375  AASSYRYTYAAT-----GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVG-  428
                 +Y+Y               F GLVK+D  TG    + +G+GV+GSE   AP+   
Sbjct  383  HGVKSQYSYHQRIPLLHEGGHTLRFTGLVKYDNDTGTSWQWDYGEGVFGSEAVFAPKPDA  442

Query  429  --SSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAE  486
              SS EDDGY++T+ TD N   S CLVFDA     GP+C++ LP R+  G H+ W  G +
Sbjct  443  DRSSVEDDGYVITMVTDSNTWKSECLVFDAQDIETGPVCRVQLPHRVPFGFHAVWARGED  502

Query  487  LRR  489
            L R
Sbjct  503  LYR  505


>gi|124003789|ref|ZP_01688637.1| retinal pigment epithelial membrane protein [Microscilla marina 
ATCC 23134]
 gi|123990844|gb|EAY30311.1| retinal pigment epithelial membrane protein [Microscilla marina 
ATCC 23134]
Length=484

 Score =  339 bits (870),  Expect = 6e-91, Method: Compositional matrix adjust.
 Identities = 189/471 (41%), Positives = 261/471 (56%), Gaps = 14/471 (2%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY  GP+ P   E  AD+L  V GE+P D+ G Y+RN  NP       YH FDGDGM+H
Sbjct  14   NPYLLGPYAPVFEEIVADNLE-VIGEIPQDIHGTYVRNGPNPRFEPEGHYHWFDGDGMLH  72

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             +   +GKA YRNR+IRT  F  E +A   LW GL      A ++  W     +KD ++T
Sbjct  73   AIQIENGKAIYRNRWIRTSNFKEETQAEKSLWQGLMGRFS-ANKDRPWNRGVPLKDTANT  131

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLF  198
             V  H G  L  +Y CGDLY IDP +  T G ES+ G         AH KVD  + E++F
Sbjct  132  AVAYHNGKLLAGWYMCGDLYAIDPVTLETKGVESFGGTL--QSKAMAHVKVDEHSNEMMF  189

Query  199  FNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWD-PRLL  257
            F+Y   + Y+ YGVVD   ++ H+  V  PGPR+PHDMA TEN+ IL D PL +D   ++
Sbjct  190  FDYELTKAYIAYGVVDGTGKVTHFTKVKTPGPRVPHDMAITENHSILMDLPLIYDLSVMV  249

Query  258  ERDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEG  315
             +    P F  E+PSRF ++ R G  + + WFEA P ++ H  NA+E+GDEI++D     
Sbjct  250  SKGKAAPVFQRELPSRFGILPRFGTADQVCWFEAKPCYIYHTINAWEEGDEIIMDCCINP  309

Query  316  DPQP---LDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINA  372
            +P P   L    T  EKL  +L   RL + L+R+  NM TG   E  L +  TEF  +N+
Sbjct  310  EPTPQKKLPPNATPEEKLNAYL---RLDAHLYRYHFNMKTGQTREYALDDRSTEFPLMNS  366

Query  373  DYAASSYRYTYAATGKPSWFL-FDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSA  431
             Y     R+ Y      S  L FDG+VK+D      E + +GDGV GSE+   P+  +  
Sbjct  367  QYLGRKSRFAYNQHLDLSEKLRFDGIVKYDTQKQTAETHWYGDGVSGSESPFIPKPHAKD  426

Query  432  EDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            EDDGY+++  TD   D S  ++ DA    D P+ ++ LP+R+  G H+ WV
Sbjct  427  EDDGYVISFVTDARTDLSEVIILDAKNIADAPLARIKLPQRVPLGFHACWV  477


>gi|254515767|ref|ZP_05127827.1| carotenoid cleavage dioxygenase 1 [gamma proteobacterium NOR5-3]
 gi|219675489|gb|EED31855.1| carotenoid cleavage dioxygenase 1 [gamma proteobacterium NOR5-3]
Length=500

 Score =  337 bits (864),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 193/482 (41%), Positives = 273/482 (57%), Gaps = 30/482 (6%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            D+PY  GP+ P   E   + L  V GE+PADL G Y RN  NPL P    YHPFDGDGM+
Sbjct  32   DNPYLHGPYAPTVHEIAKESLE-VEGELPADLRGAYFRNGPNPLLPPKNRYHPFDGDGMV  90

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
            H V F  G+  YRNR+++TD    E+ +G  + PG+  P   +    G      +KD S+
Sbjct  91   HGVYFDHGQVAYRNRWVQTDALKGEHASGKSISPGVMGPFDYSVSPFG------IKDTSN  144

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGK----ESWHGRFPFDWGVSAHPKVDNKT  193
            TD++ +R   ++ +Y  G+ Y +D  S +TLG     +  H R      +SAH K+D  T
Sbjct  145  TDILYYRKQLVSLWYNAGNPYALDTQSLDTLGDFNVPQRKHRR------MSAHSKLDWAT  198

Query  194  GELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWD  253
            GEL+FF+Y  + PYM YGV D + +LVH   V LPGPRLPHDM FT+NY IL+D P F +
Sbjct  199  GELMFFDYGDEPPYMTYGVADASGKLVHETAVDLPGPRLPHDMGFTDNYAILHDLPFFHN  258

Query  254  PRLL-ERDVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAYEQGDEIVLD  310
              +L +  + +  F+ ++P+RF +  R GN   +RWFE +P ++LH +N +E GD +++D
Sbjct  259  MDVLRQHHLRVLTFHKDMPTRFGIAPRYGNGDAVRWFECEPCYILHTSNCWEDGDWVIMD  318

Query  311  GFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTI  370
            G    +P P         +L   LA  RL++  +RWR N+ T  V E  L +  TEF   
Sbjct  319  GCRSTNPMP--NASKDEGELSHMLAYMRLEANNYRWRFNLRTSEVREGSLDDLNTEFNKT  376

Query  371  NADYAASSYRYTYAAT-----GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAP  425
            N  +     RY Y               F GLVK+D  +G    +S+G GV+GSE   AP
Sbjct  377  NPLFHGVYSRYAYHQRIPLLHEGGHTLRFTGLVKYDNESGRRWEWSYGPGVFGSEAVYAP  436

Query  426  RVG---SSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            + G   +S EDDGY++TL TD  D +S+CLVFDA     GP+ ++ +P+R+ SG H+ W 
Sbjct  437  KTGATRASGEDDGYVITLVTDSKDWSSWCLVFDAQDIEAGPVARVRMPQRVPSGFHATWA  496

Query  483  PG  484
             G
Sbjct  497  RG  498


>gi|84502108|ref|ZP_01000256.1| possible dioxygenase [Oceanicola batsensis HTCC2597]
 gi|84389468|gb|EAQ02187.1| possible dioxygenase [Oceanicola batsensis HTCC2597]
Length=511

 Score =  331 bits (849),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 193/489 (40%), Positives = 272/489 (56%), Gaps = 31/489 (6%)

Query  16   DDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRN-TENPLHPAFATYHPFDGD  74
            D DHPY  G + P   E+D++DL  V GE+P DL G Y+ N       P    YH +DGD
Sbjct  34   DYDHPYLHGAFAPSDVEYDSEDLE-VEGEIPTDLCGAYVMNGPSQRFEPVNKKYHYYDGD  92

Query  75   GMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKD  134
              +  + FRDGKA +R R++R   F+ E +AG  +WPGLA P     R  G      +KD
Sbjct  93   AQLRAIYFRDGKATFRQRYLRNGAFIVEEKAGKAIWPGLAGPYDF--RLPG----SPIKD  146

Query  135  ASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTG  194
             S+TD+I H G  L+ +Y  GD Y++DP +  T G+E+  G+      +SAH K D  TG
Sbjct  147  VSNTDIIYHNGNLLSLWYMAGDPYKVDPLTLETTGRENLKGKLKH--SLSAHSKTDPLTG  204

Query  195  ELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDP  254
            EL FFNY  Q PYM YG+ D    L   +D+ L GPR PHDM  TENY IL+D P + D 
Sbjct  205  ELFFFNYQDQPPYMSYGMADAEGNLKFDIDIDLNGPRSPHDMGLTENYAILHDLPFYHDV  264

Query  255  RLLERDVHLPR---FYPEIPSRFAVVAR--RGNDIRWFEADPTFVLHFTNAYEQGDEIVL  309
             +L+   H  R   F+ ++P+RF ++ R  R + ++WFEA+P ++LH +N++E+GD + +
Sbjct  265  DILK--AHGRRVMGFHRDVPARFGLIDRFGRSDKVQWFEAEPCYILHVSNSWEEGDWVHM  322

Query  310  DGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGT  369
             G  + DP P   G  +   L   +A  R    L+RW  N+ TG   E  + E+ TEF T
Sbjct  323  IGCRQDDPMPQKDG--RDHHLASMMAYRRRSHVLYRWSFNVKTGETREGMIDEANTEFPT  380

Query  370  INADYAASSYRYTYA--------ATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSET  421
            +N        RY++          T +     F+GL+++DL TG  + Y +G+GVYGSE 
Sbjct  381  VNTHMLGRKTRYSFNQIIPVPQDGTLEGRCQTFNGLMRYDLETGETQRYDYGEGVYGSEA  440

Query  422  AMAPRVGSSA---EDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTH  478
             +A   GS     E   Y V  TTD N   S+CL+FDAA     PI ++ +P RIS G H
Sbjct  441  PVAAAQGSGKGADETRAYPVIFTTDSNTWQSHCLIFDAADITR-PIARVKIPRRISIGFH  499

Query  479  SAWVPGAEL  487
            + WV G++L
Sbjct  500  TTWVDGSDL  508


>gi|221065797|ref|ZP_03541902.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
 gi|220710820|gb|EED66188.1| Carotenoid oxygenase [Comamonas testosteroni KF-1]
Length=480

 Score =  328 bits (840),  Expect = 2e-87, Method: Compositional matrix adjust.
 Identities = 193/471 (41%), Positives = 264/471 (57%), Gaps = 26/471 (5%)

Query  32   EWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIHVVGFRDGKAFYRN  91
            E D  D   V GE+P DL+G+Y+RN  N  +P    YH +DGDGM+H V F  G+A YRN
Sbjct  23   EEDHWDNLQVIGELPVDLNGLYVRNGPNAFYPPEWRYHAYDGDGMLHAVRFERGRASYRN  82

Query  92   RFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHRGIALTSF  151
            +++RT+G L E  AG  LW GL E  +    E        +K+ ++TDV  H G  L  +
Sbjct  83   KWVRTEGLLEEQAAGHALWKGLKEAPRADTPEQP------LKNTANTDVKFHAGRLLAMW  136

Query  152  YQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYG  211
            Y+ G  Y +DP +  T+G     GR      +SAH + D  TGEL+FF+Y  + PYM YG
Sbjct  137  YRSGLPYSLDPITLETVGNGDVDGRIK---RLSAHSRPDEHTGELVFFDYDTKPPYMCYG  193

Query  212  VVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLLERDVHLPRFYPEIP  271
            VVD   +L H ++VP+  P LPHDMA TENY IL+DFPL  DP  L    +  RF+ + P
Sbjct  194  VVDAQRKLRHMIEVPMSQPSLPHDMAVTENYSILHDFPLRPDPEALAIGRYKVRFFADQP  253

Query  272  SRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVLDG----FYEGDPQPLDTGGT  325
            SRF V+ R GN  D+RWFEA PT++LH  NA+E+G E+V+ G     YE D   LD+   
Sbjct  254  SRFGVIPRYGNASDVRWFEARPTYMLHVVNAWEEGQEVVMIGTPYRMYEKDDGSLDS---  310

Query  326  KWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESI-TEFGTINADYAASSYRYTYA  384
              E+L R + + +    L+ WR N+ TG   E  + + + TEF  IN+ Y     R++Y 
Sbjct  311  --ERLERTIHMRQRDFLLYEWRFNLETGKTSERVIDDVLNTEFPVINSAYQGRKNRWSYH  368

Query  385  AT---GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLT  441
                 G      F GLVK+DL TG +  YS G   + +E   APR  +  EDDGYLV   
Sbjct  369  VIFPQGGLEEPRFPGLVKYDLETGGYVAYSAGPQYFYNEGGFAPRDNAIGEDDGYLVMFV  428

Query  442  TDMNDDASYCLVFDA--ARPGDGPICKLALPERISSGTHSAWVPGAELRRW  490
             +     S   VFDA  +R  DGP+ ++ LP R+  G H+ +V  + L +W
Sbjct  429  WNPTTRQSEVQVFDAKGSRMADGPVARILLPRRVPHGFHATYVSQSNLDKW  479


>gi|341614431|ref|ZP_08701300.1| 9-cis-epoxycarotenoid dioxygenase [Citromicrobium sp. JLT1363]
Length=476

 Score =  319 bits (817),  Expect = 9e-85, Method: Compositional matrix adjust.
 Identities = 183/476 (39%), Positives = 265/476 (56%), Gaps = 23/476 (4%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY  G +  Q  E    DL  V GE+P DL G Y+RN  NP       +H FDG+GM+H
Sbjct  15   NPYVQGFYAAQPEEVTKTDLE-VIGELPTDLWGAYVRNGPNPFEVPDVPHHWFDGEGMVH  73

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             + F +GKA YRNR++ +D  +A+ +  G    G+  P    +         + KD ++T
Sbjct  74   SIYFENGKAEYRNRYVLSDDNVADMKGDGAEARGVLVPSNRDR------PNKVYKDTANT  127

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLF  198
            D+++H G  +  +Y  G   R+D  +  TLG E + G+ P +  VSAH K+D +TGE LF
Sbjct  128  DLVLHDGKLMALWYISGTPVRLDARTLETLGNEDFGGKLPRN--VSAHGKIDPETGEFLF  185

Query  199  FNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLLE  258
            F+YS  EP+M +GVV   +EL H+  + LPGPRLPHDM FTENYVIL+D P+ +    L 
Sbjct  186  FDYSLYEPWMSFGVVSPKSELTHFAKIDLPGPRLPHDMGFTENYVILHDLPVVFTESGLR  245

Query  259  RDVHLPRFYPEIPSRFAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGFY---  313
              +   +   +  +RF VV R G  +D++WFE DP ++ H  N++E+GDE+V+       
Sbjct  246  NGMWQIK-TEQRGARFGVVPRNGTNDDVKWFETDPCYLYHVANSWEEGDEVVMVACRMVP  304

Query  314  -EGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINA  372
               DP P      ++  +   +A   L +    WR+NM TG +   QL + ++EF  IN 
Sbjct  305  NNFDPDP---AHGQFASMVNVMA---LHAYAWEWRMNMKTGEITSRQLDDRLSEFPAINQ  358

Query  373  DYAASSYRYTY-AATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSA  431
            DYA    RY+Y  A        F+GL+K+DL TG  + Y F DG  GSE   APR G+  
Sbjct  359  DYAGRKTRYSYHVAMAHERLQRFEGLIKYDLETGEKQEYLFEDGQGGSEPVFAPRTGAKD  418

Query  432  EDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAEL  487
            EDDGY++T  T      S  L+ DA +  DGPI ++ LP R+ +G H+ W  G ++
Sbjct  419  EDDGYVITFVTHTETGESEVLILDAKKFADGPIARIPLPSRVPAGFHATWADGDKI  474


>gi|297180493|gb|ADI16707.1| lignostilbene-alpha,beta-dioxygenase and related enzymes [uncultured 
gamma proteobacterium HF0010_05D02]
Length=511

 Score =  311 bits (796),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 186/480 (39%), Positives = 265/480 (56%), Gaps = 28/480 (5%)

Query  18   DHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMI  77
            D+PY  G + P   E D D L  + GE+P+DL G Y RN  NP+      YHPFDGDGM+
Sbjct  41   DNPYLHGVYAPTNRELDQDKLEII-GELPSDLRGTYYRNGANPVFEPKDRYHPFDGDGMV  99

Query  78   HVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASS  137
            H +   D  + Y NR+I T  F  E  A   + PG+  P   +  E G      +KD S+
Sbjct  100  HALHISDDGSRYVNRWIDTPAFSEEATARESVSPGVMGPFDYSVSEFG------IKDTSN  153

Query  138  TDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELL  197
            TD+    G  ++ +Y  G+   +DP +  T  ++++H        +SAH KVD  TGELL
Sbjct  154  TDIFTLNGDLVSLWYNAGNPIALDPMTLET--RKAFHLDGRDKPKMSAHSKVDWNTGELL  211

Query  198  FFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            +F+Y+   PYM YGV +   E++H V + LPG RLPHD+ FT+NY +L+D P F D  +L
Sbjct  212  YFDYNDAPPYMTYGVANAKGEVIHEVQIDLPGARLPHDIGFTQNYTVLHDLPFFHDLDVL  271

Query  258  ER-DVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAYEQGDEIVLDGFYE  314
            +   + +  F+ +IP+RF ++ R G    IRWF+ +P ++LH +N +E+GD +V+DG   
Sbjct  272  KNHKLRVLTFHRDIPTRFGLIPRFGESKAIRWFDCEPCYILHVSNCWEEGDWVVMDGCRS  331

Query  315  GDPQPL---DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTIN  371
             +P P    D G     +L   LA  RL++  +RWR N++TG V E  + +  TEF   N
Sbjct  332  VNPMPKAYEDEG-----ELSHMLAYMRLEANNYRWRFNLITGEVREGDIDDLNTEFNKTN  386

Query  372  ADYAASSYRYTY----AATGKPSWFL-FDGLVKHDLLTGNHECYSFGDGVYGSETAMAPR  426
              Y     RY Y        +  + L F GLVK+D  TG    + +G GV GSE   AP+
Sbjct  387  PLYGGQKSRYAYHQYIPTHDEGGYTLRFTGLVKYDNETGKSWRFDYGPGVLGSEAVYAPK  446

Query  427  VGSSA---EDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVP  483
            VG++    EDDGY+V    D  D  S+  V+DA     GPI K+ LP R+ SG H+ WVP
Sbjct  447  VGATCHDEEDDGYVVNFVHDTKDWRSWFCVYDAKDIERGPIAKVRLPGRVPSGFHATWVP  506


>gi|339328145|ref|YP_004687837.1| apocarotenoid-15,15'-oxygenase [Cupriavidus necator N-1]
 gi|338170746|gb|AEI81799.1| apocarotenoid-15,15'-oxygenase [Cupriavidus necator N-1]
Length=480

 Score =  309 bits (792),  Expect = 7e-82, Method: Compositional matrix adjust.
 Identities = 191/466 (41%), Positives = 256/466 (55%), Gaps = 20/466 (4%)

Query  34   DADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRF  93
            D+ D   V G VPADL+G+Y+RN  N   P    YH +DGDGM+H V FR+GK  YRNR+
Sbjct  25   DSFDELPVIGCVPADLNGLYVRNGPNNYFPPDWRYHAYDGDGMLHAVRFRNGKVSYRNRW  84

Query  94   IRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHRGIALTSFYQ  153
            I T     E   G  LW GL EP++  + +        +K+ S+TDV  H G  +T +Y+
Sbjct  85   IATSALQEEKAEGRALWKGLKEPLRADRPDEP------LKNTSNTDVKYHAGRLITMWYR  138

Query  154  CGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVV  213
             G  Y +DP S  T G   + G       +SAH K D  TGEL+FF+Y    P+M YGV+
Sbjct  139  SGMPYAVDPDSLQTFGPADFSGAVT---RISAHSKPDEHTGELMFFDYGLTRPFMEYGVI  195

Query  214  DQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLLERDVHLPRFYPEIPSR  273
              + ++VH  ++PL  P LPHDMA TE+Y IL+DFPL  D   L    +  RF    PSR
Sbjct  196  GPDRKVVHRTEIPLDAPSLPHDMAITEHYSILHDFPLRPDAEALLAGRYKLRFDVSQPSR  255

Query  274  FAVVARRG--NDIRWFEADPTFVLHFTNAYEQGDEIVLDGF-YEGDPQPLDTGGTKWEKL  330
            FAV+ R G  ++IRWF A PT++LH  NA+E+GDEIV+ G  Y     P   G     +L
Sbjct  256  FAVIPRHGHADEIRWFNAKPTYMLHVVNAWEEGDEIVMIGTPYRIHAGP--DGQPDARRL  313

Query  331  FRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESI-TEFGTINADYAASSYRYTYAAT---  386
             R + L +    L++WR N+ TG   E  + + + TEF  IN+ Y     R++Y      
Sbjct  314  ERTIHLRQRDFLLYQWRFNLKTGETRENPIDDVLNTEFPVINSMYQGRRNRWSYNVVFPH  373

Query  387  GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMND  446
            G      F GLVK+DL TG +  YS G   + +E   APR  S AEDDGYLV    +  D
Sbjct  374  GGHEEPRFPGLVKYDLDTGGYVAYSAGPRHFYNEPGFAPRDNSMAEDDGYLVCFVWNPVD  433

Query  447  DASYCLVFDA--ARPGDGPICKLALPERISSGTHSAWVPGAELRRW  490
              S   VFD   A    GP+ ++ LP R+ +G H+ +V  A L RW
Sbjct  434  ARSEIQVFDCRGANLAQGPVARVLLPRRVPNGFHATFVSQATLNRW  479


>gi|172037130|ref|YP_001803631.1| retinal pigment epithelial membrane protein [Cyanothece sp. ATCC 
51142]
 gi|171698584|gb|ACB51565.1| probable retinal pigment epithelial membrane protein [Cyanothece 
sp. ATCC 51142]
Length=459

 Score =  301 bits (770),  Expect = 3e-79, Method: Compositional matrix adjust.
 Identities = 175/470 (38%), Positives = 253/470 (54%), Gaps = 26/470 (5%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY +G + P + E  A +LT VTGE+P +L GI+LRN  NP       YH FDGDGM+H
Sbjct  8    NPYLSGNFAPVSREITAHNLT-VTGEIPQNLRGIFLRNGPNPQFSPIGEYHWFDGDGMVH  66

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             V   DGKA YRNRFI+T G+  E EA  P+W GL EP Q+          G  K+ ++T
Sbjct  67   GVHIEDGKASYRNRFIQTRGYCLEKEANKPIWTGLLEPPQMDN------PYGPSKNTANT  120

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRF--PFDWGVSAHPKVDNKTGEL  196
             ++ H    L + ++ G+ + +     +TLG +++ G+   PF    +AHPK+D  TGE+
Sbjct  121  ALVYHAD-RLLALWEGGEPHALTVPELDTLGPDNFEGKLMSPF----TAHPKIDPMTGEM  175

Query  197  LFFNYSK-QEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPR  255
            +FF YS  Q PY++YG++    +L+  V + LP   + HD A TENY I  D PL + P 
Sbjct  176  MFFGYSMVQPPYLQYGIISPQGDLLKTVPIDLPVGVMMHDFAITENYTIFLDLPLTFRPE  235

Query  256  LLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVLDGFY  313
             +++     +F  + PSRF +V R+GN  D+RWFE +  ++ H  NAYE+GDEIVL    
Sbjct  236  RMQKGESPLQFEHDTPSRFGIVPRQGNNDDVRWFEGNSCYIFHTLNAYEEGDEIVLIA--  293

Query  314  EGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINAD  373
                      GT      R    +    RLH WR N+ TG V E+ L +  +EF  IN  
Sbjct  294  ------CRMNGTTVLGEVREETKESDIPRLHEWRFNLKTGEVKEQGLCDLPSEFPRINEQ  347

Query  374  YAASSYRYTYAAT-GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAE  432
            Y     RY Y+    + S   F+G++KHD   G  + + FG   YG E   AP   +  E
Sbjct  348  YTGRKSRYGYSGKMAESSNPKFNGIIKHDFEKGGFDIHHFGSHKYGGEPIFAPNPDADKE  407

Query  433  DDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            DDG+L+T   D   + S  ++ DA      P+  + +P+R+  G H  W+
Sbjct  408  DDGWLLTFVHDEGSNTSELVIIDAQDFTASPVATIQIPQRVPYGFHGMWL  457


>gi|67920149|ref|ZP_00513669.1| Retinal pigment epithelial membrane protein [Crocosphaera watsonii 
WH 8501]
 gi|67857633|gb|EAM52872.1| Retinal pigment epithelial membrane protein [Crocosphaera watsonii 
WH 8501]
Length=462

 Score =  295 bits (754),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 174/473 (37%), Positives = 251/473 (54%), Gaps = 32/473 (6%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY +G + P   E   ++LT V GE+P +L G++LRN  NP       YH FDGDGMIH
Sbjct  8    NPYLSGNFAPVNQETTENNLT-VIGEIPRNLRGMFLRNGPNPQFLPIGQYHWFDGDGMIH  66

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             V   +GKA YRNRF++T G+  E EA  PLW GL EP Q+          G  K+ ++T
Sbjct  67   GVHIENGKASYRNRFVQTRGYGLEKEANKPLWTGLLEPPQMDN------PYGTSKNPANT  120

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRF--PFDWGVSAHPKVDNKTGEL  196
             ++ H G  L + ++ G+ + +     N+LG  ++  +   PF    +AHPKVD  TGE+
Sbjct  121  ALVYHAG-RLLALWEGGEPHALTVPELNSLGSYNFDNKLVSPF----TAHPKVDPVTGEM  175

Query  197  LFFNYS-KQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPR  255
            +FF YS  Q PY++YG++    EL+  V + +P   + HD A TENY I  D PL + P 
Sbjct  176  MFFGYSFAQPPYLQYGIISPQGELLRTVPIDIPVGVMMHDCAITENYTIFLDLPLTFRPE  235

Query  256  LLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVLDGFY  313
             + +     +F    PSRF +  R+GN  D+RWFE+D  ++ H  NAYE+GDE+VL    
Sbjct  236  RMYKGEPPLQFEHNTPSRFGITPRQGNNEDVRWFESDSCYIFHTLNAYEEGDEVVLIACR  295

Query  314  EGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINAD  373
                  L       +        D    RLH+WR N+ TG V E+ L +  +EF  IN  
Sbjct  296  MNATTVLGEANEDVK--------DSDIPRLHQWRFNLTTGEVKEQPLCDLPSEFPRINEQ  347

Query  374  YAASSYRYTY----AATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGS  429
            Y     RY Y    AA+ +P    FDG++KHD   GN E ++FG   YG E   AP   +
Sbjct  348  YTGRKTRYGYSGKMAASSEPK---FDGIIKHDFEKGNFEIHNFGSHRYGGEPIFAPNPSA  404

Query  430  SAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
              ++ G+L+T   D     S  ++ DA      P+ K+ +P+R+  G H  W+
Sbjct  405  VTDEQGWLLTFVYDEASKVSELVIIDAQDFTASPVAKIQIPQRVPYGFHGMWL  457


>gi|126656544|ref|ZP_01727805.1| Retinal pigment epithelial membrane protein [Cyanothece sp. CCY0110]
 gi|126622230|gb|EAZ92937.1| Retinal pigment epithelial membrane protein [Cyanothece sp. CCY0110]
Length=459

 Score =  292 bits (748),  Expect = 9e-77, Method: Compositional matrix adjust.
 Identities = 173/470 (37%), Positives = 251/470 (54%), Gaps = 26/470 (5%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY +G + P + E  A +LT VTGE+P +L G++LRN  NP       YH FDGDGMIH
Sbjct  8    NPYLSGNFAPVSREITAHNLT-VTGEIPKNLRGMFLRNGPNPQFSPIGEYHWFDGDGMIH  66

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             V   DGK  YRNRF++T G+  E EA  PLW G+ EP Q+          G +K+ ++T
Sbjct  67   GVHIEDGKVSYRNRFVQTRGYCLEKEANKPLWTGMLEPPQMDN------PYGPLKNTANT  120

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRF--PFDWGVSAHPKVDNKTGEL  196
             ++ H    L + ++ G+ + +     +TLG  ++ G+   PF    +AHPK+D  TGE+
Sbjct  121  ALVYHAD-RLLALWEGGEPHALMVPELDTLGSYNFDGKLTSPF----TAHPKIDPVTGEM  175

Query  197  LFFNYSK-QEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPR  255
            +FF YS  Q PY++YG+V    EL+  V + LP   + HD A TENY I  D P  + P 
Sbjct  176  MFFGYSMIQPPYLQYGIVSSQGELLKTVPIDLPVGVMMHDFAITENYTIFLDLPFTFRPD  235

Query  256  LLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVLDGFY  313
             +++     +F  + PSRF +V R+GN  DIRWFE++  ++ H  NAYE+GDEIVL    
Sbjct  236  RMQKGESPLKFENDTPSRFGIVPRQGNNEDIRWFESNSCYIFHTLNAYEKGDEIVLIACR  295

Query  314  EGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINAD  373
                  L     + E        +     LH W  N+ TG V E++L +  +EF  IN  
Sbjct  296  MNATTVLGEATEETE--------ESDIPHLHEWHFNLKTGEVKEQKLCDLPSEFPRINEQ  347

Query  374  YAASSYRYTYAAT-GKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAE  432
            Y      Y Y+      S   F+G++KHD   G  + + FG   YGSE   AP   +  E
Sbjct  348  YTGRKTCYGYSGKMADSSEPKFNGIIKHDFEKGGFDIHHFGRHRYGSEPIFAPNPDAEKE  407

Query  433  DDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWV  482
            D+G+L+T   D   + S  ++ DA      PI K+ +P+R+  G H  W+
Sbjct  408  DEGWLLTFIHDEGSNTSELVIIDAQDFTASPIAKIQIPQRVPYGFHGMWL  457


>gi|75909914|ref|YP_324210.1| retinal pigment epithelial membrane protein [Anabaena variabilis 
ATCC 29413]
 gi|75703639|gb|ABA23315.1| Retinal pigment epithelial membrane protein [Anabaena variabilis 
ATCC 29413]
Length=463

 Score =  291 bits (745),  Expect = 2e-76, Method: Compositional matrix adjust.
 Identities = 175/474 (37%), Positives = 250/474 (53%), Gaps = 27/474 (5%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY  G + P   E   D L  V GE+P DL G+++RN  NP       YH FDGDGM+H
Sbjct  7    NPYLEGNFAPVHEEITTDTLK-VIGELPPDLSGMFIRNGPNPQWTPIGQYHWFDGDGMLH  65

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQ--LAKREHGWGARGLMKDAS  136
             V   +GKA YRNR++RT  +  E+EAG  +W G  EP Q  L  R  G           
Sbjct  66   GVRISNGKATYRNRYVRTQRWQIEHEAGQAIWTGFMEPPQPELPSRNTG-----------  114

Query  137  STDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGEL  196
            +T +I H G  L + ++ G  + I      T+G+ +++ +       +AHPKVD  TGE+
Sbjct  115  NTALIWHAG-QLLALWEGGAPHAIQVPDLETIGEYTYNNQ--LSSAFTAHPKVDPATGEM  171

Query  197  LFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRL  256
            +FF YS   PY+ Y VV    ELV  + + LP   + HD A T NY I  D PL +    
Sbjct  172  MFFGYSFAPPYLHYSVVSATGELVRTIPIDLPMGVMMHDFAITANYTIFMDLPLTFSVER  231

Query  257  LERDVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAYEQGDEIVLDGFYE  314
            ++R   +  F  + PSRF ++ R G++  IRWF A   +V H  NAYE  DE+VL     
Sbjct  232  MQRGEPMLMFESDRPSRFGILPRHGDNSHIRWFTAPSCYVFHTLNAYEDKDEVVLFACPM  291

Query  315  GDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADY  374
                 L +  ++ +        +    RLHRWR N+ TG VHEE L +  +EF  IN ++
Sbjct  292  RSTTVLASPDSQTDP-------EADIPRLHRWRFNLKTGKVHEEMLDDVASEFPRINENF  344

Query  375  AASSYRYTYAA-TGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAED  433
               + +Y Y +   K S  LF+GL+K+DL     + Y +G G YGSE    PR G++ ED
Sbjct  345  LGQATKYGYTSRLAKGSIPLFEGLIKYDLSNAKSQNYEYGQGRYGSEAVFVPRPGATVED  404

Query  434  DGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAEL  487
            DG+L+T   D+ +D+S  +V +A      PI ++ LP+R+  G H  WV   +L
Sbjct  405  DGWLITYVYDIGEDSSELVVINAQDINSEPIARVLLPQRVPYGFHGIWVTEEQL  458


>gi|17228601|ref|NP_485149.1| hypothetical protein all1106 [Nostoc sp. PCC 7120]
 gi|17130452|dbj|BAB73063.1| all1106 [Nostoc sp. PCC 7120]
Length=475

 Score =  288 bits (738),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 176/482 (37%), Positives = 253/482 (53%), Gaps = 27/482 (5%)

Query  11   STLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHP  70
            +T+     +PY  G + P   E   D L  V GE+P +L G+++RN  NP       YH 
Sbjct  11   NTMTTTAVNPYLEGNFAPVHEEITTDTLK-VIGELPPELSGMFVRNGPNPQWTPIGQYHW  69

Query  71   FDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQ--LAKREHGWGA  128
            FDGDGM+H V   +GKA YRNR++RT  +  E+EAG  +W GL EP Q  L  R  G   
Sbjct  70   FDGDGMLHGVRISNGKATYRNRYVRTQRWQIEHEAGQAIWTGLMEPPQTELPSRNTG---  126

Query  129  RGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPK  188
                    +T +I H G  L + ++ G  Y I      ++G+ +++ +       +AHPK
Sbjct  127  --------NTALIWHAG-QLLALWEGGAPYAIQVPDLASIGEYTYNNQ--LSSAFTAHPK  175

Query  189  VDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDF  248
            VD  TGE++FF YS   PY+ Y VV    ELV  V + LP   + HD A T NY I  D 
Sbjct  176  VDPVTGEMMFFGYSFAPPYLHYSVVSATGELVRTVPIDLPMGVMMHDFAITANYTIFMDL  235

Query  249  PLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAYEQGDE  306
            PL +    ++R   +  F  + PSRF ++ R G++  IRWFEA   +V H  NAYE  DE
Sbjct  236  PLTFSVERMQRGEPMLMFESDRPSRFGILPRHGDNSQIRWFEAPSCYVFHTLNAYEDKDE  295

Query  307  IVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITE  366
            +VL          L +  ++ +        +    RLHRWR ++ TG VHEE L +  +E
Sbjct  296  VVLFACPMRSTTVLASPDSQTDP-------EADIPRLHRWRFHLKTGKVHEEMLDDVASE  348

Query  367  FGTINADYAASSYRYTYAA-TGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAP  425
            F  IN ++     +Y Y +   K S  LF+GL+K+DL     + Y +G G YGSE    P
Sbjct  349  FPRINENFLGQPTQYGYTSRLAKGSIPLFEGLIKYDLSNAKSQNYEYGQGRYGSEAVFVP  408

Query  426  RVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGA  485
            R G++ EDDG+L+T   D  +++S  +V +A      PI ++ LP+R+  G H  WV   
Sbjct  409  RPGATVEDDGWLITYVYDTGEESSELVVINAQDINSEPIARVLLPQRVPYGFHGIWVTEE  468

Query  486  EL  487
            +L
Sbjct  469  QL  470


>gi|119511691|ref|ZP_01630796.1| Retinal pigment epithelial membrane protein [Nodularia spumigena 
CCY9414]
 gi|119463676|gb|EAW44608.1| Retinal pigment epithelial membrane protein [Nodularia spumigena 
CCY9414]
Length=472

 Score =  288 bits (736),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 172/481 (36%), Positives = 248/481 (52%), Gaps = 27/481 (5%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY    + P   E   D L  V GE+PA+L G+++RN  NP       YH FDGDGM+H
Sbjct  7    NPYLNHNFAPVRDEITTDTLK-VIGELPANLSGMFVRNGPNPQWSPIGKYHWFDGDGMLH  65

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             V   +G+A Y NR++RT G+  E EAG  +W GL EP Q+     G+      K+ ++T
Sbjct  66   GVRISNGQATYCNRYVRTKGWKIEQEAGKAVWSGLLEPPQMDNPHGGY------KNTANT  119

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLF  198
             ++ H G  L +  + G  + I      T+G+ +++ +       +AHPKVD K GE++F
Sbjct  120  ALVWHAGQML-ALNEGGAPHAIKLPDLQTIGEYTYNNQLVS--AFTAHPKVDPKNGEMMF  176

Query  199  FNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLLE  258
            F YS   PY++Y +V    E+V  V + LP   + HD A TENY I  D PL + P   +
Sbjct  177  FGYSFAPPYLQYSIVSAAGEIVKTVPIDLPMGVMMHDFAITENYTIFMDLPLTFSPERAQ  236

Query  259  RDVHLPRFYPEI-------PSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVL  309
            R      F  ++       PSRF ++ R G+  +IRWFE+ P +V H  NAYE  DEIVL
Sbjct  237  RGEPAMMFESDVYDGLRLRPSRFGIIPRHGDNSNIRWFESSPCYVFHTLNAYEDQDEIVL  296

Query  310  DGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGT  369
                      L    ++ +        +    RLHRWR N+ TG V EE L +   EF  
Sbjct  297  VACRMSSTSVLKADDSQTDP-------EADIPRLHRWRFNLSTGKVQEEMLDDVSAEFPR  349

Query  370  INADYAASSYRYTYAATGKPSWF-LFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVG  428
            IN +    + RY YA     S   LFDGL+K+DL  G  + ++F  G YG E   AP +G
Sbjct  350  INENLLGQATRYGYAGRMDNSPLPLFDGLIKYDLNNGKSQTHAFKQGCYGGEAVFAPSIG  409

Query  429  SSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAELR  488
            +  EDDG+L+T   D     S  +V +A      P+ ++ +P+R+  G H  WV   +L 
Sbjct  410  AKHEDDGWLITFVHDEALQKSEIVVLNAQDVTAEPVARVLIPQRVPYGFHGTWVSEEQLS  469

Query  489  R  489
            +
Sbjct  470  K  470


>gi|254410750|ref|ZP_05024528.1| Retinal pigment epithelial membrane protein [Microcoleus chthonoplastes 
PCC 7420]
 gi|196182105|gb|EDX77091.1| Retinal pigment epithelial membrane protein [Microcoleus chthonoplastes 
PCC 7420]
Length=466

 Score =  286 bits (733),  Expect = 5e-75, Method: Compositional matrix adjust.
 Identities = 176/490 (36%), Positives = 259/490 (53%), Gaps = 35/490 (7%)

Query  5    IVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPA  64
            +VG  +ST   +   P+  G + P   E  AD+LT V GE+P DL G+++RN  NP  P+
Sbjct  1    MVGNNMSTTTVN---PFLAGNFAPVQNEITADELT-VIGELPQDLSGMFVRNGPNPQFPS  56

Query  65   FATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREH  124
             A YH F GDGM+H V   +GKA YR+R++RT  F  E E G  L  GL   VQ  +   
Sbjct  57   SANYHWFGGDGMLHGVQISNGKASYRDRYVRTPRFEKERETGQAL-EGLTASVQNQESSP  115

Query  125  GWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVS  184
                R      ++T VI H    L + Y+ G+ Y I      T+G  ++  +    +  +
Sbjct  116  SLTNR------ANTSVIWHSDHFL-ALYEGGEPYGIKLPELETIGAYTFEDKLASAF--T  166

Query  185  AHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVI  244
            AHPK+D  TGE++FF YS Q P++ Y +V ++ ELV  V + LP P + HD A T++Y +
Sbjct  167  AHPKIDPVTGEMMFFGYSPQPPFLTYSIVSRSGELVRTVPIDLPEPVMMHDFAITQDYTL  226

Query  245  LNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGND--IRWFEADPTFVLHFTNAYE  302
              D P+ ++P+       + +F  E PSRF +V R G++  IRWFE+   +  H  NAY+
Sbjct  227  FMDLPMVFNPQ----GEAMLQFKSERPSRFGIVPRHGDNSSIRWFESPSCYAFHILNAYQ  282

Query  303  QGDEIVLDGFYEGDPQPL----DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEE  358
            +GDE+VL          L    +TGG            D  + RL++WR N+ TG V E+
Sbjct  283  EGDEVVLIACRMSSCTVLTALEETGGDP----------DSNKPRLYQWRFNLRTGNVQEK  332

Query  359  QLSESITEFGTINADYAASSYRYTYAATGKPSWF-LFDGLVKHDLLTGNHECYSFGDGVY  417
             L E I++F  IN        RY Y A    +   LF+G++K+D   G  + + +G G Y
Sbjct  333  PLDERISDFPRINEQLMGRKMRYGYTAKMADNPMPLFEGVIKYDFDNGTSQVHHYGAGRY  392

Query  418  GSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGT  477
            G E   APR   +AEDDG+L+T   D N D S  +V +A      P+ ++ +P+R+  G 
Sbjct  393  GGEAVFAPRPNGTAEDDGWLITFVHDHNSDTSELVVLNAQDLTAEPVARVLMPQRVPYGF  452

Query  478  HSAWVPGAEL  487
            H  WV   +L
Sbjct  453  HGTWVSQEQL  462


>gi|186683149|ref|YP_001866345.1| carotenoid oxygenase [Nostoc punctiforme PCC 73102]
 gi|186465601|gb|ACC81402.1| Carotenoid oxygenase [Nostoc punctiforme PCC 73102]
Length=460

 Score =  283 bits (724),  Expect = 5e-74, Method: Compositional matrix adjust.
 Identities = 177/482 (37%), Positives = 246/482 (52%), Gaps = 37/482 (7%)

Query  13   LPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFD  72
            +P    +PY    + P   E   D L  V GE+P DL G+++RN  NP       YH FD
Sbjct  1    MPTIAVNPYLDRNFAPIREEITTDKLP-VIGELPLDLSGMFVRNGPNPQWTPIGQYHWFD  59

Query  73   GDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLM  132
            GDGM+H V   +G A YRNR+++T G+  E EAG  LW GL EP ++          G  
Sbjct  60   GDGMLHGVQISNGVATYRNRYVQTSGWKKEREAGEALWSGLLEPPRMDN------PHGPR  113

Query  133  KDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNK  192
            K+ ++T ++ H G  L +  + G  + I      T+G+ S++G+       +AHPKVD  
Sbjct  114  KNTANTALVWHAGQML-ALNESGKPHAIKLPELETIGEYSYNGK--LISAFTAHPKVDPV  170

Query  193  TGELLFFNYSK-QEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLF  251
            TGE++FF YS    PY++Y VV    EL+  V + L    + HD A TENY I  D PL 
Sbjct  171  TGEMIFFGYSVFTPPYLQYSVVSAQGELLRTVPIDLSIGVMMHDFAITENYTIFMDLPLT  230

Query  252  WDPRLLERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVL  309
            +     +R   +  F  + PSRF +V R G+  +IRWFE+   +V H  NAYE GDE+VL
Sbjct  231  FSAERSQRGEPVMMFERDRPSRFGIVPRHGDNSNIRWFESPSCYVFHTLNAYEDGDEVVL  290

Query  310  DG--------FYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLS  361
                          D QP   G                  RL+RWR N+ TG V EE L 
Sbjct  291  IACRMSSTTVLISDDSQPDPEGNIP---------------RLYRWRFNLSTGTVREEMLD  335

Query  362  ESITEFGTINADYAASSYRYTYAATGKPSWF-LFDGLVKHDLLTGNHECYSFGDGVYGSE  420
            +  +EF  IN +      RY Y      S   LF+G++K+D  +G  + + FG G YGSE
Sbjct  336  DVTSEFPRINENLLGRQTRYGYTNKIANSPVPLFEGIIKYDFSSGKSQTHKFGQGRYGSE  395

Query  421  TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA  480
               APR G+ AEDDG+LVT   D N + S  +V +A      P+ ++ +P+R+  G H  
Sbjct  396  AVFAPRPGAIAEDDGWLVTFVHDENSNTSELVVVNAQDVTAEPVARVIIPQRVPYGFHGT  455

Query  481  WV  482
            WV
Sbjct  456  WV  457


>gi|75908268|ref|YP_322564.1| retinal pigment epithelial membrane protein [Anabaena variabilis 
ATCC 29413]
 gi|75701993|gb|ABA21669.1| Retinal pigment epithelial membrane protein [Anabaena variabilis 
ATCC 29413]
Length=765

 Score =  283 bits (723),  Expect = 6e-74, Method: Compositional matrix adjust.
 Identities = 175/498 (36%), Positives = 262/498 (53%), Gaps = 47/498 (9%)

Query  13   LPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFD  72
            + E+  H + T  + P   E  AD+L  V G++P +L G +LR   NP       YH FD
Sbjct  287  VKEELAHRFLTLNYAPVRKEITADNLE-VIGKLPQELSGTFLRIGPNPRFAPLGLYHWFD  345

Query  73   GDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLM  132
            GDGMIH V  ++GKA YRNR++RT+G+  E + G  +WPGL   + L + +   G   +M
Sbjct  346  GDGMIHGVQIKNGKASYRNRYVRTEGWKIEEKEGQAIWPGL---LNLPRFDEPHGI--MM  400

Query  133  KDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNK  192
            K+ ++T ++ H G  L + ++ G+ Y I   + +T+G  +++ +  F +   AHPKVD +
Sbjct  401  KNVANTALVWHHG-RLLALWEGGEPYEISLPNLDTVGSYTFNEQLTFPF--CAHPKVDAR  457

Query  193  TGELLFFNYSK-QEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLF  251
            TGE++FF Y    +PY++YG+V    ++V  + + +P P   HD A TE Y I  D PL 
Sbjct  458  TGEMMFFGYQPLTKPYVQYGIVSPEGKIVKTIPIDIPSPISMHDFAITEKYTIFLDMPLA  517

Query  252  WDP-RLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLD  310
              P R+++  V L  F    PSRF ++ R G +IRWF      V H  NAYE+G+E++L 
Sbjct  518  LKPMRVMQGKVPL-VFERNKPSRFGIIPRHGGEIRWFTVPSCMVYHVVNAYEEGNEVILV  576

Query  311  GFYEGDPQPLDTGGTKWEKLF---RFLALDRLQ------------SRLHRWRLNMVTGAV  355
             +              W +LF   R  ALD +             ++L+RWR N+ TG V
Sbjct  577  AYR-----------MDWTQLFIPDRENALDFVNTDTSSEKLAPEMTKLYRWRFNLSTGQV  625

Query  356  HEEQL-SESITEFGTINADYAASSYRYTYAATG-----KPSWFLFDGLVKHDLLTGNHEC  409
             EE L  + I EF  IN        RY Y+  G     +P   LFDG+ K+DL +G  + 
Sbjct  626  KEEILDKDEICEFPRINDRLIGCKMRYVYSGIGAMYMERP---LFDGVKKYDLESGTAQS  682

Query  410  YSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLAL  469
              FG G +G E   APR G   EDDG+++T   D  +  S  +V DA      P+ ++ L
Sbjct  683  VYFGRGRFGGECVFAPRPGGKTEDDGWVLTYIYDAVNKRSEFIVLDAQNITAEPVARVIL  742

Query  470  PERISSGTHSAWVPGAEL  487
            P+R+  G H  WV   ++
Sbjct  743  PQRVPFGFHCEWVSSEKM  760


>gi|113477252|ref|YP_723313.1| carotenoid oxygenase [Trichodesmium erythraeum IMS101]
 gi|110168300|gb|ABG52840.1| Carotenoid oxygenase [Trichodesmium erythraeum IMS101]
Length=464

 Score =  282 bits (721),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 174/474 (37%), Positives = 242/474 (52%), Gaps = 26/474 (5%)

Query  19   HPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIH  78
            +PY    + P + E   ++L  + GE+P DL G+YLRN  NP       Y   DGDGMIH
Sbjct  8    NPYLMSNFAPVSKEITTNNLE-IKGELPRDLSGMYLRNGPNPQFTPLGKYDWMDGDGMIH  66

Query  79   VVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASST  138
             V    G+A YRNR++RT GF  E + G  +W G  EP Q+          G  K+ ++ 
Sbjct  67   GVRISGGRAEYRNRYVRTGGFEVEKDLGYAVWSGRLEPPQMNN------PYGPYKNVANN  120

Query  139  DVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLF  198
             +  H G  L + ++ G  Y I   S  T G     G    D   +AHPK+D  TGEL+F
Sbjct  121  GLTFHNG-KLLALWEAGLPYEIRVPSLETTGPYLCDGYL--DSAFTAHPKIDPMTGELIF  177

Query  199  FNYSKQ-EPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDPRLL  257
            F Y+    PY++YG++    EL+    + +P P  PHD A T+NY IL D PL + P   
Sbjct  178  FGYALDVAPYLKYGIISARGELLQITPINIPVPSGPHDFAITKNYTILMDLPLRFRPERE  237

Query  258  ERDVHLPRFYPEIPSRFAVVARRGN--DIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEG  315
            ++ +    F   +PSRF ++ R GN  DI WFEA P ++ H  NAYE  DEI+L G    
Sbjct  238  KQGLPAWMFETGVPSRFGILPRCGNNEDIHWFEAQPCYMNHILNAYEFEDEIILYG----  293

Query  316  DPQPLDTGGTKWEKLFRFLALDRLQS--RLHRWRLNMVTGAVHEEQLSESITEFGTINAD  373
                     T W   +   A D  ++  R++ W  N+ TGAV E  L +  +EF  IN  
Sbjct  294  ----CRMSSTYW---YPGTARDPNENIPRMYGWAFNLKTGAVREGMLDKRPSEFPCINHR  346

Query  374  YAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSETAMAPRVGSSAED  433
            +     RY Y +       LFDG++K+D  TG    + FG+G YG  T  APR+GS  ED
Sbjct  347  FVGRQMRYGYTSRMASLRPLFDGIIKYDFSTGRSLSHDFGEGRYGGATTFAPRIGSIDED  406

Query  434  DGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSAWVPGAEL  487
            DG+L+T   D  +  S  LV DA      P+ ++ LP+R+  G H  WV   +L
Sbjct  407  DGWLLTFVYDEKEKHSELLVIDAQDIMGEPVARVMLPQRVPYGFHGTWVSEMQL  460



Lambda     K      H
   0.320    0.139    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1083597119368




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40