BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0915c

Length=423
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|31792103|ref|NP_854596.1|  PPE family protein [Mycobacterium b...   808    0.0   
gi|15840336|ref|NP_335373.1|  PPE family protein [Mycobacterium t...   808    0.0   
gi|340625926|ref|YP_004744378.1|  PPE family protein [Mycobacteri...   806    0.0   
gi|289446484|ref|ZP_06436228.1|  PPE family protein [Mycobacteriu...   806    0.0   
gi|254363844|ref|ZP_04979890.1|  PPE family protein [Mycobacteriu...   806    0.0   
gi|339293924|gb|AEJ46035.1|  PPE family protein [Mycobacterium tu...   804    0.0   
gi|254549895|ref|ZP_05140342.1|  PPE family protein [Mycobacteriu...   777    0.0   
gi|183982547|ref|YP_001850838.1|  PPE family protein [Mycobacteri...   410    3e-112
gi|183981466|ref|YP_001849757.1|  PPE family protein [Mycobacteri...   307    2e-81 
gi|167967684|ref|ZP_02549961.1|  PPE family protein [Mycobacteriu...   300    3e-79 
gi|167967057|ref|ZP_02549334.1|  PPE family protein [Mycobacteriu...   294    2e-77 
gi|183984579|ref|YP_001852870.1|  PPE family protein [Mycobacteri...   273    3e-71 
gi|118619580|ref|YP_907912.1|  PPE family protein [Mycobacterium ...   264    2e-68 
gi|240172900|ref|ZP_04751559.1|  PPE family protein [Mycobacteriu...   241    1e-61 
gi|183981478|ref|YP_001849769.1|  PPE family protein [Mycobacteri...   207    3e-51 
gi|118466613|ref|YP_881225.1|  PPE family protein [Mycobacterium ...   203    6e-50 
gi|342859619|ref|ZP_08716272.1|  PPE family protein [Mycobacteriu...   202    1e-49 
gi|336458159|gb|EGO37142.1|  PPE-repeat containing protein [Mycob...   197    3e-48 
gi|289447416|ref|ZP_06437160.1|  PPE family protein [Mycobacteriu...   196    7e-48 
gi|340626711|ref|YP_004745163.1|  PPE family protein [Mycobacteri...   194    2e-47 
gi|31792891|ref|NP_855384.1|  PPE family protein [Mycobacterium b...   194    2e-47 
gi|167969175|ref|ZP_02551452.1|  PPE family protein [Mycobacteriu...   194    3e-47 
gi|307079711|ref|ZP_07488881.1|  PPE family protein [Mycobacteriu...   193    4e-47 
gi|15841163|ref|NP_336200.1|  PPE family protein [Mycobacterium t...   193    4e-47 
gi|57116898|ref|YP_177827.1|  PPE family protein [Mycobacterium t...   193    5e-47 
gi|342861307|ref|ZP_08717955.1|  PPE family protein [Mycobacteriu...   193    5e-47 
gi|289745858|ref|ZP_06505236.1|  PPE family protein [Mycobacteriu...   192    9e-47 
gi|15841271|ref|NP_336308.1|  PPE family protein [Mycobacterium t...   192    1e-46 
gi|254550715|ref|ZP_05141162.1|  PPE family protein [Mycobacteriu...   192    1e-46 
gi|339631855|ref|YP_004723497.1|  PPE family protein [Mycobacteri...   191    2e-46 
gi|289574478|ref|ZP_06454705.1|  PPE family protein [Mycobacteriu...   191    2e-46 
gi|121637612|ref|YP_977835.1|  PPE family protein [Mycobacterium ...   191    3e-46 
gi|15841279|ref|NP_336316.1|  PPE family protein [Mycobacterium t...   187    2e-45 
gi|254821012|ref|ZP_05226013.1|  PPE family protein, PPE31 [Mycob...   187    2e-45 
gi|148823022|ref|YP_001287776.1|  PPE family protein [Mycobacteri...   187    3e-45 
gi|340626818|ref|YP_004745270.1|  PPE family protein [Mycobacteri...   187    3e-45 
gi|254231991|ref|ZP_04925318.1|  PPE family protein [Mycobacteriu...   187    3e-45 
gi|57116922|ref|YP_177845.1|  PPE family protein [Mycobacterium t...   187    3e-45 
gi|289447423|ref|ZP_06437167.1|  PPE family protein [Mycobacteriu...   187    3e-45 
gi|289574486|ref|ZP_06454713.1|  PPE family protein [Mycobacteriu...   187    3e-45 
gi|289443283|ref|ZP_06433027.1|  PPE family protein [Mycobacteriu...   187    4e-45 
gi|296170357|ref|ZP_06851948.1|  PPE family protein [Mycobacteriu...   187    4e-45 
gi|342857520|ref|ZP_08714176.1|  PPE family protein [Mycobacteriu...   186    5e-45 
gi|57116920|ref|YP_177653.1|  PPE family protein [Mycobacterium t...   186    6e-45 
gi|148661613|ref|YP_001283136.1|  PPE family protein [Mycobacteri...   186    7e-45 
gi|296164997|ref|ZP_06847552.1|  PPE family protein [Mycobacteriu...   186    9e-45 
gi|340626811|ref|YP_004745263.1|  PPE family protein [Mycobacteri...   185    1e-44 
gi|240171072|ref|ZP_04749731.1|  PPE family protein [Mycobacteriu...   184    2e-44 
gi|31792997|ref|NP_855490.1|  PPE family protein [Mycobacterium b...   184    4e-44 
gi|57116921|ref|YP_177844.1|  PPE family protein [Mycobacterium t...   183    4e-44 


>gi|31792103|ref|NP_854596.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57116795|ref|YP_177765.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|121636838|ref|YP_977061.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 59 more sequence titles
 Length=423

 Score =  808 bits (2086),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/423 (100%), Positives = 423/423 (100%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
Sbjct  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
Sbjct  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
Sbjct  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420

Query  421  PPR  423
            PPR
Sbjct  421  PPR  423


>gi|15840336|ref|NP_335373.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|254231223|ref|ZP_04924550.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|13880500|gb|AAK45187.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|124600282|gb|EAY59292.1| PPE family protein [Mycobacterium tuberculosis C]
Length=426

 Score =  808 bits (2086),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/423 (100%), Positives = 423/423 (100%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  4    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  63

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
Sbjct  64   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  123

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
Sbjct  124  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  183

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  184  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  243

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
Sbjct  244  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  303

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  304  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  363

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  364  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  423

Query  421  PPR  423
            PPR
Sbjct  424  PPR  426


>gi|340625926|ref|YP_004744378.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004116|emb|CCC43253.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=423

 Score =  806 bits (2081),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/423 (99%), Positives = 422/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAM VPPSLVAANRSRLMSL
Sbjct  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMMVPPSLVAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
Sbjct  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
Sbjct  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420

Query  421  PPR  423
            PPR
Sbjct  421  PPR  423


>gi|289446484|ref|ZP_06436228.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289419442|gb|EFD16643.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=423

 Score =  806 bits (2081),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/423 (99%), Positives = 422/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
Sbjct  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
Sbjct  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGP QGHPLSS
Sbjct  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPMQGHPLSS  300

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420

Query  421  PPR  423
            PPR
Sbjct  421  PPR  423


>gi|254363844|ref|ZP_04979890.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|134149358|gb|EBA41403.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
Length=423

 Score =  806 bits (2081),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/423 (99%), Positives = 422/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
Sbjct  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAA SALPPFTPPVQGTGPAGPA
Sbjct  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAATSALPPFTPPVQGTGPAGPA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
Sbjct  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420

Query  421  PPR  423
            PPR
Sbjct  421  PPR  423


>gi|339293924|gb|AEJ46035.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
Length=423

 Score =  804 bits (2076),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 421/423 (99%), Positives = 421/423 (99%), Gaps = 0/423 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
Sbjct  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
Sbjct  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQN AAIAATQAEYAEMWAQDA VMYSYEGASAAASALPPFTPPVQGTGPAGPA
Sbjct  121  VAANILGQNRAAIAATQAEYAEMWAQDADVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
Sbjct  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300
            AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
Sbjct  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS  300

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
            ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
Sbjct  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360

Query  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420
            DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
Sbjct  361  DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN  420

Query  421  PPR  423
            PPR
Sbjct  421  PPR  423


>gi|254549895|ref|ZP_05140342.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|294996398|ref|ZP_06802089.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|297633436|ref|ZP_06951216.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|297730421|ref|ZP_06959539.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313657748|ref|ZP_07814628.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
 gi|323720626|gb|EGB29704.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=409

 Score =  777 bits (2006),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/409 (100%), Positives = 409/409 (100%), Gaps = 0/409 (0%)

Query  15   MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG  74
            MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG
Sbjct  1    MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG  60

Query  75   WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA  134
            WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA
Sbjct  61   WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA  120

Query  135  ATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAV  194
            ATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAV
Sbjct  121  ATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAV  180

Query  195  ADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSAQPIVIPTPIGELD  254
            ADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSAQPIVIPTPIGELD
Sbjct  181  ADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSAQPIVIPTPIGELD  240

Query  255  VIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGG  314
            VIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGG
Sbjct  241  VIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGG  300

Query  315  AAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLS  374
            AAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLS
Sbjct  301  AAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLS  360

Query  375  GMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGNPPR  423
            GMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGNPPR
Sbjct  361  GMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGNPPR  409


>gi|183982547|ref|YP_001850838.1| PPE family protein [Mycobacterium marinum M]
 gi|183175873|gb|ACC40983.1| PPE family protein [Mycobacterium marinum M]
Length=404

 Score =  410 bits (1053),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 279/392 (72%), Positives = 307/392 (79%), Gaps = 3/392 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPEVNS RMY+GPGPESMLAAAAAWD VAAEL++AAVSYGSVVS LI+EPWMG 
Sbjct  1    MDFGLLPPEVNSGRMYTGPGPESMLAAAAAWDTVAAELSAAAVSYGSVVSALILEPWMGS  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            AAAAM AAATPYVGWLAATAA  KETA QAR AA AF TAFA TVPP  +AANRSRLMSL
Sbjct  61   AAAAMTAAATPYVGWLAATAAQVKETAYQARMAASAFATAFASTVPPPRIAANRSRLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VAANILGQNS AIAA QAEYAEMWAQDAA M+SY GASA A+ L PFT P+Q T P G  
Sbjct  121  VAANILGQNSPAIAAIQAEYAEMWAQDAAAMHSYLGASATAATLTPFTEPIQSTDPPGSM  180

Query  181  AAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVG  239
            A AAA   A   A     AT LA+L PG L+D LS L   ADPLTSGLLGIA++LNPQ+ 
Sbjct  181  AEAAAVAQAAGAAAPTITATRLAELFPGDLADSLSTLTTAADPLTSGLLGIATSLNPQLT  240

Query  240  SAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPW-HIGLYGNAGGLGPTQGHPL  298
            +A  + +PTPIGELDV+ALYIA++ATGSIAL++TNT RPW + G   + GG  PT G  +
Sbjct  241  TAAAMTVPTPIGELDVLALYIAAVATGSIALSVTNTFRPWNYYGSDAHGGGSNPTHGGAI  300

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSA  358
            SS   E    WGPFGGAAPV+ GVGHAALVG+LSVPH WTTAAPEIQLAV+A  T +SS 
Sbjct  301  SSTRKEDATDWGPFGGAAPVTVGVGHAALVGSLSVPHGWTTAAPEIQLAVEAMRTGASSR  360

Query  359  GADPTALNGMPAGLLSGMALASLAARGTTGGG  390
              D TALNGM AGLL G ALA  AARGT GGG
Sbjct  361  -VDSTALNGMSAGLLGGAALAGWAARGTIGGG  391


>gi|183981466|ref|YP_001849757.1| PPE family protein [Mycobacterium marinum M]
 gi|183174792|gb|ACC39902.1| PPE family protein [Mycobacterium marinum M]
Length=416

 Score =  307 bits (787),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 245/427 (58%), Positives = 287/427 (68%), Gaps = 23/427 (5%)

Query  2    DFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPA  61
            DFG +PPEVNS  MY+GPGP SML +A AWDG+AA +++AA SYGSV++ L +E W+GPA
Sbjct  8    DFGGIPPEVNSGLMYAGPGPGSMLTSATAWDGLAAAMSTAAASYGSVIAGLKLESWLGPA  67

Query  62   AAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLV  121
            AA+MA AA PY GWL+A AA A++TATQARAAA AF  AFA TVPP L+AANR++L+SL 
Sbjct  68   AASMATAAAPYAGWLSAAAAQAQQTATQARAAAAAFEEAFAATVPPPLIAANRNQLVSLA  127

Query  122  AANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAA  181
            AAN LGQNS AI A QAEYAEMWAQDAA MYSY GAS AAS L PF  P Q   PAGP  
Sbjct  128  AANTLGQNSPAIEAAQAEYAEMWAQDAAAMYSYAGASEAASMLTPFNQPSQTVDPAGPLT  187

Query  182  AAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSA  241
             AAA  A  A                     L AL+ +AD  TSGL G+ S+    +  A
Sbjct  188  QAAAAAATNAQTALAQ---------------LLALSTSADLPTSGLPGLTSSPTGPL-PA  231

Query  242  QPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYG-NAGGLGPTQGHPLSS  300
             PI IPTPIGELD I LYIA IA+GSIAL+ITNT RPW++     + GGLGPT G  L S
Sbjct  232  APIQIPTPIGELDAIGLYIAVIASGSIALSITNTFRPWNLTESSGHGGGLGPTHGGLLGS  291

Query  301  ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA  360
             T E         GAAP+SA VGHAALVGALSVPH+WT AAPEI+LAV+A P+ S S+G 
Sbjct  292  TTAESGADSDGGAGAAPMSAAVGHAALVGALSVPHNWTLAAPEIKLAVEALPSTSVSSG-  350

Query  361  DPTALNGMPAGLLSGMALASLAARGT--TGGGGTRSGTSTDGQEDGRKPPVVVIREQPPP  418
             P  L G+P GLLSGMA+ASLA RG   TG    R     +G+   ++ P VV   +PPP
Sbjct  351  -PPDLGGVPTGLLSGMAVASLAGRGIGATGTPSVRDAAPEEGEGQPKRRPTVVKVPKPPP  409

Query  419  --GNPPR  423
              G PP 
Sbjct  410  ADGLPPH  416


>gi|167967684|ref|ZP_02549961.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=156

 Score =  300 bits (768),  Expect = 3e-79, Method: Compositional matrix adjust.
 Identities = 150/150 (100%), Positives = 150/150 (100%), Gaps = 0/150 (0%)

Query  274  NTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSV  333
            NTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSV
Sbjct  7    NTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSV  66

Query  334  PHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTR  393
            PHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTR
Sbjct  67   PHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTR  126

Query  394  SGTSTDGQEDGRKPPVVVIREQPPPGNPPR  423
            SGTSTDGQEDGRKPPVVVIREQPPPGNPPR
Sbjct  127  SGTSTDGQEDGRKPPVVVIREQPPPGNPPR  156


>gi|167967057|ref|ZP_02549334.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=160

 Score =  294 bits (753),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 157/160 (99%), Positives = 157/160 (99%), Gaps = 0/160 (0%)

Query  15   MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG  74
            MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG
Sbjct  1    MYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVG  60

Query  75   WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA  134
            WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA
Sbjct  61   WLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIA  120

Query  135  ATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGT  174
            ATQAEYAEMWAQDAAVMYSYEGASA ASALP FTP VQGT
Sbjct  121  ATQAEYAEMWAQDAAVMYSYEGASADASALPTFTPTVQGT  160


>gi|183984579|ref|YP_001852870.1| PPE family protein [Mycobacterium marinum M]
 gi|183177905|gb|ACC43015.1| PPE family protein [Mycobacterium marinum M]
Length=422

 Score =  273 bits (699),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 223/426 (53%), Positives = 266/426 (63%), Gaps = 32/426 (7%)

Query  2    DFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPA  61
            DFG LPPEVNS  +Y+GPG   ML AA AWDG+A  L SAA SY SVVS L +E WMGPA
Sbjct  4    DFGALPPEVNSGLLYTGPGAAPMLTAATAWDGLATVLNSAAASYASVVSGLTLESWMGPA  63

Query  62   AAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLV  121
            +A+MAAAA PY  WLA     A++TA QARAAA AF TAFA+ VPP L+AANRS++ SLV
Sbjct  64   SASMAAAAAPYATWLAVANEQARQTAAQARAAATAFETAFAVVVPPPLIAANRSQVASLV  123

Query  122  AANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAA  181
             AN+LGQN+ AI   QAEYAEMWAQDAAVMY Y  AS AAS L  FT P+Q T P+G  A
Sbjct  124  VANVLGQNTPAIETLQAEYAEMWAQDAAVMYQYSAASEAASTLAAFTSPMQSTDPSGAQA  183

Query  182  AAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSA  241
            + AA  AA         +     P    +D    LAA    + +G           + + 
Sbjct  184  STAAGAAAAGTTAQTTASQ----PTTTATDTAQGLAAEVPTIPTG---------SDLAAP  230

Query  242  QPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYG-----NAGGLGPTQGH  296
              I IPTP+GELD++A YIA  AT S++L+  NTARPW           N GG+ PTQG+
Sbjct  231  AAISIPTPVGELDLLAAYIAVAATASLSLSAVNTARPWSYSTNNDHAQPNGGGVAPTQGN  290

Query  297  PLSSATDEPEPHWGPFG-GAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPT--  353
             L   T+ P+           P SA VGHAALVGALSVPHSW  AAPEI+LAV++ P+  
Sbjct  291  TL--GTERPDAEVLVSAPNIVPTSAFVGHAALVGALSVPHSWAMAAPEIRLAVESLPSAG  348

Query  354  -FSSSAGADPTALNGM-PAGLLSGMALASLAARGTTGGGG---TRSGTSTDGQEDGRKPP  408
              S+ AG D   + GM P GLLSGMALASLA RG TG G    + S T+ D Q   RKP 
Sbjct  349  GLSAPAGPD---IGGMAPTGLLSGMALASLAGRGATGAGSRSPSESATNEDEQPQ-RKPT  404

Query  409  VVVIRE  414
            VVVI++
Sbjct  405  VVVIQK  410


>gi|118619580|ref|YP_907912.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118571690|gb|ABL06441.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=423

 Score =  264 bits (675),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 221/426 (52%), Positives = 264/426 (62%), Gaps = 32/426 (7%)

Query  2    DFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPA  61
            DFG LPPEVNS  +Y+GPG   ML AA AWDG+A  L SAA SY SVVS L +E  MGPA
Sbjct  5    DFGALPPEVNSGLLYAGPGAAPMLTAATAWDGLATVLNSAAASYASVVSGLTLESRMGPA  64

Query  62   AAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLV  121
            +A+MAAAA PY  WLA     A++TA QARAAA AF TAFA+ VPP L+AANRS++ SLV
Sbjct  65   SASMAAAAAPYATWLAVANEQARQTAAQARAAATAFETAFAVVVPPPLIAANRSQVASLV  124

Query  122  AANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAA  181
             AN+LGQN+ AI   QAEYAEMWAQDAAVMY Y  AS AAS L  FT PVQ T P+   A
Sbjct  125  VANVLGQNTPAIETLQAEYAEMWAQDAAVMYQYSAASEAASTLAAFTSPVQSTDPSRAQA  184

Query  182  AAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSA  241
            + AA  AA         +     P    +D    LAA    + +G           + + 
Sbjct  185  STAAGAAAAGTTAQTTASQ----PTTAATDTAQGLAAEVPTIPAG---------SDLAAP  231

Query  242  QPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYG-----NAGGLGPTQGH  296
              I IPTP+GELD++A YIA  AT S++L+  NTARPW           N GG+ PTQG+
Sbjct  232  AAISIPTPVGELDLLAAYIAVAATASLSLSAVNTARPWSYSTNNDHAQPNGGGVAPTQGN  291

Query  297  PLSSATDEPEPHWGPFG-GAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPT--  353
             L   T+ P+           P SA VGHAALVGALSVPHSW  AAPEI+LAV++ P+  
Sbjct  292  TL--GTERPDAEVLVSAPNVVPTSAFVGHAALVGALSVPHSWAMAAPEIRLAVESLPSAG  349

Query  354  -FSSSAGADPTALNGM-PAGLLSGMALASLAARGTTGGGG---TRSGTSTDGQEDGRKPP  408
              S+ AG D   + G+ P GLLSGMALASLA RG TG G    + S T+ D Q   RKP 
Sbjct  350  GLSAPAGPD---MGGVAPTGLLSGMALASLAGRGATGAGSRSPSESATNEDEQPQ-RKPT  405

Query  409  VVVIRE  414
            VVVI++
Sbjct  406  VVVIQK  411


>gi|240172900|ref|ZP_04751559.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=394

 Score =  241 bits (616),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 208/413 (51%), Positives = 251/413 (61%), Gaps = 34/413 (8%)

Query  24   MLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVGWLAATAALA  83
            ML AA AW+ + A L SAAVSY SVVS L +E W+GPA+A+MAAAA PY  WL+A A  A
Sbjct  1    MLTAATAWESLTAVLNSAAVSYASVVSALTLESWLGPASASMAAAAAPYAEWLSAAAEQA  60

Query  84   KETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIAATQAEYAEM  143
            ++TA QA AAA A+ TA A  VPP L+AANRS+L +LV  N  GQN+ AI A QA+YAEM
Sbjct  61   RQTAAQASAAAAAYETARATAVPPPLIAANRSQLATLVTTNTFGQNTPAIEAIQADYAEM  120

Query  144  WAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAVADAQATLAQ  203
            WAQDAAVMY Y  AS  AS L PF+ P     P   A+ AA        + A   A    
Sbjct  121  WAQDAAVMYQYAEASETASTLMPFSQPAHTADPTASASQAAQVAGGADASAAAGPAASIG  180

Query  204  LPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSAQPIVIPTPIGELDVIALYIASI  263
              P  L   L A AA++ PL S L   A++          I IPTPIG+LDV+ALYI++I
Sbjct  181  --PETLQ--LLATAASSAPLGSQLPEPAAS----------ITIPTPIGDLDVLALYISAI  226

Query  264  ATGSIALAITNTARPWHIGLYG-----NAGGLGPTQGHPLSSATD--EPEPHWGPFGGAA  316
             T S++LA+ NTARPW+ G  G     + GG+ PTQG P+SS  +     P       +A
Sbjct  227  GTASLSLAVVNTARPWYFGYNGFRPAPSPGGIEPTQGEPISSEREVLASSPR---SVASA  283

Query  317  PVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGM  376
            PVSAG G AALVG LSVPH WT AAPEI+LAV++ P  S+   A PT L G P GLLSGM
Sbjct  284  PVSAGSGQAALVGGLSVPHGWTMAAPEIKLAVESLP--SAGLTAAPTDLGGAPMGLLSGM  341

Query  377  ALASLAARGTTGGGGTRSGTSTDGQEDG---RKPPVVVIREQPP----PGNPP  422
            A  +  A    GG G R       +EDG   RKP VVVI++ PP    PGN P
Sbjct  342  A-LAGLAGRGAGGMGPRVPNEAAAEEDGEPKRKPTVVVIQQPPPAGGTPGNRP  393


>gi|183981478|ref|YP_001849769.1| PPE family protein [Mycobacterium marinum M]
 gi|183174804|gb|ACC39914.1| PPE family protein [Mycobacterium marinum M]
Length=427

 Score =  207 bits (527),  Expect = 3e-51, Method: Compositional matrix adjust.
 Identities = 169/412 (42%), Positives = 216/412 (53%), Gaps = 54/412 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPE+NS RMY GPG   MLAAA  WD +AAEL + A  Y S +  L    W GP
Sbjct  1    MDFGALPPEINSGRMYVGPGSGPMLAAAVVWDELAAELYATAAGYRSTLDGLTGGSWRGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+A+MAAAA PYV W+ ATAA A+   +QA+ AA A+ TAFA TVPP ++AANR+ LM L
Sbjct  61   ASASMAAAAAPYVAWMTATAAQAELAGSQAKVAASAYETAFAATVPPPVIAANRALLMGL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  NI GQN+ AIAAT+A YAEMWAQDAA MY+Y G+SA A+ + PFT P Q T P    
Sbjct  121  VFTNIFGQNTPAIAATEAHYAEMWAQDAAAMYAYAGSSATATQVTPFTEPPQITSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
                      +GAV+ A A          SDI + L+     + + L G+A++ NP    
Sbjct  177  ----------SGAVSQAAAVTEAATASASSDITAQLSPLIAVVPNALQGMATSGNPAAAI  226

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHI-GLYGNAGG--LGPTQGHP  297
            A    +  P G +  +  +   + T            P+ I GL G  GG  L   Q + 
Sbjct  227  AGLPDVALPAGIITDLQNFTTILDT---------LDGPFTIQGLTGVPGGPFLAFGQVYA  277

Query  298  LSSATDEPEPHWGP----FGGAAPV---------------------SAGVGHAALVGALS  332
             S      +  + P     GG AP+                     S  +GHAALVG +S
Sbjct  278  FSQNMVGAQAFFSPAEPVIGGLAPLAGEANLGAAGVVGGPSVGGQASGAMGHAALVGNMS  337

Query  333  VPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAAR  384
            VP  WT  AP I++ V   PT   S  A P A     + + + MAL+SLA R
Sbjct  338  VPQGWTQEAPAIRVFVSELPT---SVTAAPAATLAGESAVFNQMALSSLAGR  386


>gi|118466613|ref|YP_881225.1| PPE family protein [Mycobacterium avium 104]
 gi|118167900|gb|ABK68797.1| ppe family protein [Mycobacterium avium 104]
Length=446

 Score =  203 bits (516),  Expect = 6e-50, Method: Compositional matrix adjust.
 Identities = 165/361 (46%), Positives = 211/361 (59%), Gaps = 45/361 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            M F +LPPEVNS RMYSGPG  SMLAAA+AWD +A EL   A +  SV+S L  EPW GP
Sbjct  1    MHFAVLPPEVNSGRMYSGPGSGSMLAAASAWDELANELHVTAANIESVISGLTSEPWQGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            +AAA+ AAA   V WL ATA  A +T  Q +AAA A+ +A+AMTVPPS+VAANRSRL SL
Sbjct  61   SAAAVTAAAATQVEWLTATAEQAAQTGAQLKAAATAYESAYAMTVPPSVVAANRSRLASL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VA N+LGQN+ AIAAT+  Y EMWAQD A MY Y GA+ AAS + PFTPP + T  AG  
Sbjct  121  VATNLLGQNTPAIAATEVAYGEMWAQDVAAMYGYAGAAQAASRVTPFTPPQRTTNEAGMG  180

Query  181  AAAAAT-QAAG--AGAVADAQATLAQLP--PGILSDILSALAANADPLTSGLLGIASTLN  235
            A  A+  QAAG  AG V  A +    +   P  L ++ S+ ++++    SGL   +S LN
Sbjct  181  AQNASVAQAAGTSAGHVQSAVSNSNAMSAVPNALQNLASSSSSSSA--ASGLSDFSSFLN  238

Query  236  PQVGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQG  295
            P                 ++++L  A    G+             IG+ G AG +   + 
Sbjct  239  P----------------YNLVSLGSAFFGNGT-----------GLIGVSGAAGFISDAE-  270

Query  296  HPL------SSATDEPEPHWGPFG----GAAPVSAGVGHAALVGALSVPHSWTTAAPEIQ  345
            H +      S A   PE    P G    GA  VSAG+G A+ +G +SVP  W+TAAPE++
Sbjct  271  HKMTEPSAKSKAVAAPERLEPPAGSRSSGATTVSAGMGRASSLGGMSVPQGWSTAAPELR  330

Query  346  L  346
            L
Sbjct  331  L  331


>gi|342859619|ref|ZP_08716272.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342132751|gb|EGT85971.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=458

 Score =  202 bits (513),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 173/438 (40%), Positives = 229/438 (53%), Gaps = 44/438 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDF +LPPEVNS+RMY+GPG   MLAAA AWD VAA L + A SY + ++ L   PW+GP
Sbjct  1    MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDEVAAALQTTANSYQAEITALTSGPWVGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++AAM AA TPY+ W+    A A+ETA QAR AA A+ TAFA TVPP +V ANR++L +L
Sbjct  61   SSAAMVAAITPYLEWMRTAGAQAEETANQARTAAFAYETAFAETVPPPVVTANRTQLAAL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VA N+LGQN+ AIAAT+AEY EMWA+D A M+ Y G +A+A+ L PF+ P   +      
Sbjct  121  VATNVLGQNTPAIAATEAEYGEMWARDTAAMFGYAGTTASATRLTPFSQPDPTSNSGAGQ  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            + A A     AG+  +         P +LS+   + AA +    + LLG+          
Sbjct  181  SEAVAQAGTAAGSTRNTVQQSFSAVPNLLSNAALSPAAISPTSATDLLGL----------  230

Query  241  AQPIVIPTPIGELDVIALYI---ASIATGSIALAITNTARPWHI-----GLYGN--AGGL  290
                       E D+IA+++   AS+A   I    T  A P+ +     G + +    G 
Sbjct  231  -----------ESDLIAIFLDAPASVAGLGIDAPGTLVALPFDVAGALTGFHTDDIVSGW  279

Query  291  GPTQGHPLSSATDEPEPH---WGPFGGAAPV-SAGVGHAALVGALSVPHSWTTAAPEIQL  346
               Q  P + A   P P      P GG   + SAG+G A+ VG LSVP  WT AAP I+ 
Sbjct  280  AGVQAWPGTGAVP-PSPFPVITNPAGGFGTLASAGLGQASTVGGLSVPPGWTAAAPAIRP  338

Query  347  A--VQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG------TRSGTST  398
            A  V    T  ++A A   A +     L   MA AS+A R   G GG       R+G   
Sbjct  339  AALVLPATTAGAAAPAAAAAASTGTGSLFGEMATASMAGRAMAGTGGALGRERARAGEIE  398

Query  399  DGQEDGRKPPVVVIREQP  416
                   K P  V  E P
Sbjct  399  KATRSAPKEPTTVPTEPP  416


>gi|336458159|gb|EGO37142.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=445

 Score =  197 bits (501),  Expect = 3e-48, Method: Compositional matrix adjust.
 Identities = 164/361 (46%), Positives = 210/361 (59%), Gaps = 46/361 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            M F +LPPEVNS RMYSGPG  SMLAA+A WD +A EL   A +  SV+S L  EPW GP
Sbjct  1    MHFAVLPPEVNSGRMYSGPGSGSMLAASA-WDELANELHVTAANIESVISGLTSEPWQGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            +AAA+ AAA   V WL ATA  A +T  Q +AAA A+ +A+AMTVPPS+VAANRSRL SL
Sbjct  60   SAAAVTAAAATQVEWLTATAEQAAQTGAQLKAAATAYESAYAMTVPPSVVAANRSRLASL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VA N+LGQN+ AIAAT+  Y EMWAQD A MY Y GA+ AAS + PFTPP + T  AG  
Sbjct  120  VATNLLGQNTPAIAATEVAYGEMWAQDVAAMYGYAGAAQAASRVTPFTPPQRTTNEAGMG  179

Query  181  AAAAAT-QAAG--AGAVADAQATLAQLP--PGILSDILSALAANADPLTSGLLGIASTLN  235
            A  A+  QAAG  AG V  A +    +   P  L ++ S+ ++++    SGL   +S LN
Sbjct  180  AQNASVAQAAGTSAGHVQSAVSNSNAMSAVPNALQNLASSSSSSSA--ASGLSDFSSFLN  237

Query  236  PQVGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQG  295
            P                 ++++L  A    G+             IG+ G AG +   + 
Sbjct  238  P----------------YNLVSLGSAFFGNGT-----------GLIGVSGAAGFISDAE-  269

Query  296  HPL------SSATDEPEPHWGPFG----GAAPVSAGVGHAALVGALSVPHSWTTAAPEIQ  345
            H +      S A   PE    P G    GA  VSAG+G A+ +G +SVP  W+TAAPE++
Sbjct  270  HKMTEPGAKSKAVAAPERLEPPAGSRSSGATTVSAGMGRASSLGGMSVPQGWSTAAPELR  329

Query  346  L  346
            L
Sbjct  330  L  330


>gi|289447416|ref|ZP_06437160.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420374|gb|EFD17575.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=423

 Score =  196 bits (498),  Expect = 7e-48, Method: Compositional matrix adjust.
 Identities = 171/416 (42%), Positives = 213/416 (52%), Gaps = 53/416 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPE+NS RMY+GPGP  MLAAA AWDG+A EL + A  Y S +S L    W GP
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++ +MA+AA PYV W++ATA  A+    QAR A  A+  AFA TVPP ++AANR++LM L
Sbjct  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMGL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A NI GQN+ AI  T+A+Y EMWAQDAA MY Y G+SA AS +  FT P Q T      
Sbjct  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTT---NHG  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
               A + A    A   A   L    P +LS +  AL   A P  S           Q  S
Sbjct  177  QLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTAS-----------QSAS  225

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIAL--AITNTARPWHIGL---------YGNAGG  289
            A P  + T +G L     ++    TG       +  +  P+ +G+          G +  
Sbjct  226  ATPQWV-TDLGNLST---FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSAL  281

Query  290  LGPTQGHPLSSATDEPEPHWGPFGGAAPV-----------SAGVGHAALVGALSVPHSWT  338
            LG   G P++ A          F    P+           SAG+G A LVG LSVP  WT
Sbjct  282  LGKIGGKPITGALAP----LAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWT  337

Query  339  TAAPEI---QLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG  391
             AAPEI     A+QAT        A P A    P  LL GMAL+ LA R   G  G
Sbjct  338  VAAPEIPSPAAALQAT-----RLAAAPIAATDGPGALLGGMALSGLAGRAAAGSTG  388


>gi|340626711|ref|YP_004745163.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004901|emb|CCC44047.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=385

 Score =  194 bits (494),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 156/346 (46%), Positives = 203/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LSVP +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL  324


>gi|31792891|ref|NP_855384.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|224990087|ref|YP_002644774.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|289443162|ref|ZP_06432906.1| PPE family protein [Mycobacterium tuberculosis T46]
 18 more sequence titles
 Length=385

 Score =  194 bits (494),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 156/346 (46%), Positives = 203/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LSVP +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL  324


>gi|167969175|ref|ZP_02551452.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=356

 Score =  194 bits (492),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 155/346 (45%), Positives = 203/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LS+P +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL  324


>gi|307079711|ref|ZP_07488881.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308362459|gb|EFP51310.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=376

 Score =  193 bits (491),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 171/396 (44%), Positives = 221/396 (56%), Gaps = 32/396 (8%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAV-QATPTFSSS  357
             +A   P       GG  PVSAG+G+AA +G LS+P +W  A+P +   V  A+    S 
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSD  338

Query  358  AGADPTALNGMPAGLLSGMALASLAARGTTGGGGTR  393
                P A  G    LL GM LA     G+  G G R
Sbjct  339  IVEQPEA--GAAGNLLGGMPLA-----GSGTGTGVR  367


>gi|15841163|ref|NP_336200.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881383|gb|AAK46014.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|323719795|gb|EGB28909.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=385

 Score =  193 bits (491),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 167/382 (44%), Positives = 216/382 (57%), Gaps = 27/382 (7%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAV-QATPTFSSS  357
             +A   P       GG  PVSAG+G+AA +G LS+P +W  A+P +   V  A+    S 
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAPTVGSASAPLVSD  338

Query  358  AGADPTALNGMPAGLLSGMALA  379
                P A  G    LL GM LA
Sbjct  339  IVEQPEA--GAAGNLLGGMPLA  358


>gi|57116898|ref|YP_177827.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661502|ref|YP_001283025.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148822911|ref|YP_001287665.1| PPE family protein [Mycobacterium tuberculosis F11]
 39 more sequence titles
 Length=385

 Score =  193 bits (491),  Expect = 5e-47, Method: Compositional matrix adjust.
 Identities = 155/346 (45%), Positives = 203/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LS+P +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL  324


>gi|342861307|ref|ZP_08717955.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131207|gb|EGT84488.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=417

 Score =  193 bits (490),  Expect = 5e-47, Method: Compositional matrix adjust.
 Identities = 114/176 (65%), Positives = 134/176 (77%), Gaps = 0/176 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPE+NS RMY+GPG   M+AAAAAWDG+ AEL+SAA  Y SV+S L   PW+GP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPMMAAAAAWDGLGAELSSAASGYTSVISELTHAPWVGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+++M +A TPYV WL+  AA A+ETA QARAAA AF  AFAMTVPP ++AANR  L +L
Sbjct  61   ASSSMLSAVTPYVSWLSVLAAQAEETAGQARAAAAAFEAAFAMTVPPPVIAANRVLLANL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGP  176
            VA N LGQN+ AIAAT+A+Y EMWAQDAA MY Y G+SA AS LPP T P   T P
Sbjct  121  VATNFLGQNTPAIAATEAQYMEMWAQDAAAMYGYAGSSAVASELPPLTSPPNTTTP  176


>gi|289745858|ref|ZP_06505236.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289686386|gb|EFD53874.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=385

 Score =  192 bits (488),  Expect = 9e-47, Method: Compositional matrix adjust.
 Identities = 155/346 (45%), Positives = 203/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  M+ Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMHGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LSVP +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL  324


>gi|15841271|ref|NP_336308.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31792989|ref|NP_855482.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57116916|ref|YP_177840.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 57 more sequence titles
 Length=423

 Score =  192 bits (488),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 170/416 (41%), Positives = 212/416 (51%), Gaps = 53/416 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPE+NS RMY+GPGP  MLAAA AWDG+A EL + A  Y S +S L    W GP
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++ +MA+AA PYV W++ATA  A+    QAR A  A+  AFA TVPP ++AANR++LM L
Sbjct  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A NI GQN+ AI  T+A+Y EMWAQDAA MY Y G+SA AS +  FT P Q T      
Sbjct  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTT---NHG  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
               A + A    A   A   L    P +LS +  AL   A P  S           Q  S
Sbjct  177  QLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTAS-----------QSAS  225

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIAL--AITNTARPWHIGL---------YGNAGG  289
            A P  + T +G L     ++    TG       +  +  P+ +G+          G +  
Sbjct  226  ATPQWV-TDLGNLST---FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSAL  281

Query  290  LGPTQGHPLSSATDEPEPHWGPFGGAAPV-----------SAGVGHAALVGALSVPHSWT  338
            LG   G P++ A          F    P+           SAG+G A LVG LSVP  WT
Sbjct  282  LGKIGGKPITGALAP----LAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWT  337

Query  339  TAAPEI---QLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG  391
             AAPEI     A+QAT        A P A       LL GMAL+ LA R   G  G
Sbjct  338  VAAPEIPSPAAALQAT-----RLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTG  388


>gi|254550715|ref|ZP_05141162.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
Length=385

 Score =  192 bits (487),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 155/346 (45%), Positives = 202/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A  I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFATGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LS+P +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSL  324


>gi|339631855|ref|YP_004723497.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339331211|emb|CCC26893.1| PPE family protein [Mycobacterium africanum GM041182]
Length=423

 Score =  191 bits (486),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 169/416 (41%), Positives = 212/416 (51%), Gaps = 53/416 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPE+NS RMY+GPGP  MLAAA AWDG+A EL + A  Y S +S L    W GP
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++ +MA+AA PYV W++ATA  A+    QAR A  A+  AFA TVPP ++AANR++LM L
Sbjct  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A NI GQN+ AI  T+A+Y EMWAQD+A MY Y G+SA AS +  FT P Q T      
Sbjct  120  IATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTT---NHG  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
               A + A    A   A   L    P +LS +  AL   A P  S           Q  S
Sbjct  177  QLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTAS-----------QSAS  225

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIAL--AITNTARPWHIGL---------YGNAGG  289
            A P  + T +G L     ++    TG       +  +  P+ +G+          G +  
Sbjct  226  ATPQWV-TDLGNLST---FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSAL  281

Query  290  LGPTQGHPLSSATDEPEPHWGPFGGAAPV-----------SAGVGHAALVGALSVPHSWT  338
            LG   G P++ A          F    P+           SAG+G A LVG LSVP  WT
Sbjct  282  LGKIGGKPITGALAP----LAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWT  337

Query  339  TAAPEI---QLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG  391
             AAPEI     A+QAT        A P A       LL GMAL+ LA R   G  G
Sbjct  338  VAAPEIPSPAAALQAT-----RLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTG  388


>gi|289574478|ref|ZP_06454705.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538909|gb|EFD43487.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=423

 Score =  191 bits (485),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 169/416 (41%), Positives = 212/416 (51%), Gaps = 53/416 (12%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPE+NS RMY+GPGP  MLAAA AWDG+A EL + A  Y S +S L    W GP
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++ +MA+AA PYV W++ATA  A+    QAR A  A+  AFA TVPP ++AANR++LM L
Sbjct  60   SSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A NI GQN+ AI  T+A+Y EMWAQD+A MY Y G+SA AS +  FT P Q T      
Sbjct  120  IATNIFGQNTPAIMMTEAQYMEMWAQDSAAMYGYAGSSATASRMTAFTEPPQTT---NHG  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
               A + A    A   A   L    P +LS +  AL   A P  S           Q  S
Sbjct  177  QLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTAS-----------QSAS  225

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIAL--AITNTARPWHIGL---------YGNAGG  289
            A P  + T +G L     ++    TG       +  +  P+ +G+          G +  
Sbjct  226  ATPQWV-TDLGNLST---FLGGEVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSAL  281

Query  290  LGPTQGHPLSSATDEPEPHWGPFGGAAPV-----------SAGVGHAALVGALSVPHSWT  338
            LG   G P++ A          F    P+           SAG+G A LVG LSVP  WT
Sbjct  282  LGKIGGKPITGALAP----LAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWT  337

Query  339  TAAPEI---QLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG  391
             AAPEI     A+QAT        A P A       LL GMAL+ LA R   G  G
Sbjct  338  VAAPEIPSPAAALQAT-----RLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTG  388


>gi|121637612|ref|YP_977835.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|121493259|emb|CAL71730.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
Length=385

 Score =  191 bits (484),  Expect = 3e-46, Method: Compositional matrix adjust.
 Identities = 155/346 (45%), Positives = 202/346 (59%), Gaps = 24/346 (6%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            M FG LPPEVNS RMY GPG   M+AAA+AW+G+AAEL+ AAV Y  V++TL  E W+GP
Sbjct  1    MAFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+  M  A  PYV W+ ATA  A++ A+QARAAA A+ TAFA  VPP L+AANR+RL SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            V  N+ GQN+A+IAAT+A+YAEMWAQDA  MY Y G+SA A+ + PF PP   T P    
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSP----  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQV-G  239
             +AAATQ +     A   A  AQ          SA+A     L + LLG+ S L+  +  
Sbjct  177  -SAAATQLSAVAKAAGTSAGAAQ----------SAIAELIAHLPNTLLGLTSPLSSALTA  225

Query  240  SAQPIVIPTPIG-ELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPL  298
            +A P  +   I   L +  L+  ++     A+ I N+       L  +   LG       
Sbjct  226  AATPGWLEWFINWYLPISQLFYNTVGLPYFAIGIGNS-------LITSWRALGWIGPEAA  278

Query  299  SSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEI  344
             +A   P       GG  PVSAG+G+AA +G LSVP +W  A+P +
Sbjct  279  EAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSL  324


>gi|15841279|ref|NP_336316.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13881507|gb|AAK46130.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=694

 Score =  187 bits (476),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 172/399 (44%), Positives = 215/399 (54%), Gaps = 43/399 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  227  MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  286

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  287  SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  346

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  347  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  406

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  +  + + +
Sbjct  407  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI  466

Query  235  NPQVGSAQPIVIPTPIGELDVIALYIASIATGSI------ALAITNTARPWH------IG  282
                G+       T    L V A  +   +T +        L +T     W       I 
Sbjct  467  FGPTGA-------TTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIP  519

Query  283  LYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
                  GLG   G  LS+            G A   SAG+G A LVG LSVP SW +A P
Sbjct  520  KSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSWASATP  565

Query  343  EIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  566  AVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  600


>gi|254821012|ref|ZP_05226013.1| PPE family protein, PPE31 [Mycobacterium intracellulare ATCC 
13950]
 gi|212596828|gb|ACJ35609.1| PPE48 [Mycobacterium intracellulare ATCC 13950]
Length=389

 Score =  187 bits (476),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 163/345 (48%), Positives = 211/345 (62%), Gaps = 20/345 (5%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            +DF  LPPE+NS+RMY+GPG   ML AA+AW+G+AAEL SAA+SYGS +S+L  E W GP
Sbjct  3    VDFATLPPEINSARMYAGPGSGPMLVAASAWNGLAAELRSAALSYGSALSSLTSEEWHGP  62

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+AAM AAATPYV W++ TA  A++ ATQA AAA A+  AFA TVPP  +AANR++L +L
Sbjct  63   ASAAMVAAATPYVAWMSTTATQAEQAATQAEAAAAAYEAAFAATVPPPAIAANRAQLATL  122

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A N+LGQN+ AIAAT+A+Y EMWAQDAA MY Y G+SAAA+ LP FT P Q T   G A
Sbjct  123  IATNVLGQNTPAIAATEAQYGEMWAQDAATMYGYAGSSAAATRLPMFTDPTQTTSQDGQA  182

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
              AAA   A   +  + QAT++QL   +  + L  L++  +  T    G++S L+P    
Sbjct  183  RQAAAVAQATGTSAGNQQATVSQLNTAV-PNALQTLSSPTESSTGSTSGLSSILDPNSNF  241

Query  241  AQPIVIPTPIGELD---VIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHP  297
               I   T  G LD   V+    +S   G+   A+ + A    +     A G+G T    
Sbjct  242  WNTI---TSTGALDPAQVVQTVTSSTLIGASTSALNDLASGAPV-----ATGIG-TSAQS  292

Query  298  LSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
            LS          G     A VSAG+G A+LVG LSVP SW   AP
Sbjct  293  LSGLA-------GVGNAGASVSAGLGRASLVGPLSVPPSWAPPAP  330


>gi|148823022|ref|YP_001287776.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253799147|ref|YP_003032148.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254364637|ref|ZP_04980683.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|289554417|ref|ZP_06443627.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|134150151|gb|EBA42196.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|148721549|gb|ABR06174.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253320650|gb|ACT25253.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289439049|gb|EFD21542.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=470

 Score =  187 bits (475),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 175/404 (44%), Positives = 216/404 (54%), Gaps = 53/404 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  3    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  62

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  63   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  122

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  123  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  182

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  L+G    +
Sbjct  183  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQ-LMG--QLI  239

Query  235  NPQVGSAQPIVIPTPIGELDVIALYI-----------ASIATGSIALAITNTARPWH---  280
            N   G         P G      L++           A+ A  +  L +T     W    
Sbjct  240  NAIFG---------PTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPP  290

Query  281  ---IGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSW  337
               I       GLG   G  LS+            G A   SAG+G A LVG LSVP SW
Sbjct  291  APEIPKSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSW  336

Query  338  TTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             +A P ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  337  ASATPAVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  376


>gi|340626818|ref|YP_004745270.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005008|emb|CCC44157.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=470

 Score =  187 bits (475),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 175/404 (44%), Positives = 216/404 (54%), Gaps = 53/404 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTVPPQTTNPSGLA  180

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  L+G    +
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQ-LMG--QLI  237

Query  235  NPQVGSAQPIVIPTPIGELDVIALYI-----------ASIATGSIALAITNTARPWH---  280
            N   G         P G      L++           A+ A  +  L +T     W    
Sbjct  238  NAIFG---------PTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPP  288

Query  281  ---IGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSW  337
               I       GLG   G  LS+            G A   SAG+G A LVG LSVP SW
Sbjct  289  APEIPKSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSW  334

Query  338  TTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             +A P ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  335  ASATPAVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  374


>gi|254231991|ref|ZP_04925318.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|254550817|ref|ZP_05141264.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|289757912|ref|ZP_06517290.1| PPE family protein [Mycobacterium tuberculosis T85]
 32 more sequence titles
 Length=468

 Score =  187 bits (475),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 172/399 (44%), Positives = 215/399 (54%), Gaps = 43/399 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  180

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  +  + + +
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI  240

Query  235  NPQVGSAQPIVIPTPIGELDVIALYIASIAT------GSIALAITNTARPWH------IG  282
                G+       T    L V A  +   +T       +  L +T     W       I 
Sbjct  241  FGPTGA-------TTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIP  293

Query  283  LYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
                  GLG   G  LS+            G A   SAG+G A LVG LSVP SW +A P
Sbjct  294  KSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSWASATP  339

Query  343  EIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  340  AVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  374


>gi|57116922|ref|YP_177845.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661615|ref|YP_001283138.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967396|ref|ZP_02549673.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 11 more sequence titles
 Length=468

 Score =  187 bits (475),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 174/395 (45%), Positives = 217/395 (55%), Gaps = 35/395 (8%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  180

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLG--IAS  232
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  L+G  I +
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQ-LMGQLINA  239

Query  233  TLNPQVGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWH------IGLYGN  286
               P   +    V  T    +   + + A+ A  +  L +T     W       I     
Sbjct  240  IFGPTGATTYQNVFVT-AANVTKFSTW-ANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSL  297

Query  287  AGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQL  346
              GLG   G  LS+            G A   SAG+G A LVG LSVP SW +A P ++L
Sbjct  298  GAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSWASATPAVRL  343

Query  347  AVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
                 P  ++S  A P     +PA LL  MAL S+
Sbjct  344  VANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  374


>gi|289447423|ref|ZP_06437167.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289569881|ref|ZP_06450108.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289750382|ref|ZP_06509760.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289753904|ref|ZP_06513282.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289420381|gb|EFD17582.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289543635|gb|EFD47283.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289690969|gb|EFD58398.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289694491|gb|EFD61920.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=472

 Score =  187 bits (475),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 175/404 (44%), Positives = 216/404 (54%), Gaps = 53/404 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  3    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  62

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  63   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  122

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  123  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  182

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  L+G    +
Sbjct  183  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQ-LMG--QLI  239

Query  235  NPQVGSAQPIVIPTPIGELDVIALYI-----------ASIATGSIALAITNTARPWH---  280
            N   G         P G      L++           A+ A  +  L +T     W    
Sbjct  240  NAIFG---------PTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPP  290

Query  281  ---IGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSW  337
               I       GLG   G  LS+            G A   SAG+G A LVG LSVP SW
Sbjct  291  APEIPKSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSW  336

Query  338  TTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             +A P ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  337  ASATPAVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  376


>gi|289574486|ref|ZP_06454713.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538917|gb|EFD43495.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=470

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 176/426 (42%), Positives = 223/426 (53%), Gaps = 44/426 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  180

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  +  + + +
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAI  240

Query  235  NPQVGSAQPIVIPTPIGELDVIALYIASIAT------GSIALAITNTARPWH------IG  282
                G+       T    L V A  +   +T       +  L +T     W       I 
Sbjct  241  FGPTGA-------TTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIP  293

Query  283  LYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
                  GLG   G  LS+            G A   SAG+G A LVG LSVP SW +A P
Sbjct  294  KSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSWASATP  339

Query  343  EIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL-AARGTTGGGGTRSGTSTDGQ  401
             ++L     P  ++S  A P     +PA LL  MAL S+             +G+    +
Sbjct  340  AVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARAR  395

Query  402  EDGRKP  407
             +GR P
Sbjct  396  ANGRTP  401


>gi|289443283|ref|ZP_06433027.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|339631862|ref|YP_004723504.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|289416202|gb|EFD13442.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|339331218|emb|CCC26901.1| PPE family protein [Mycobacterium africanum GM041182]
Length=470

 Score =  187 bits (474),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 175/404 (44%), Positives = 216/404 (54%), Gaps = 53/404 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGL PPE+ S  MY GPG   MLAAA AWDG+AAEL S A SY S+V  +  E W+GP
Sbjct  1    MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A MAAAA PYV W++ T+A AK  A QARAA  A+ TAFA  VPP  +AANRS+L+SL
Sbjct  61   SSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAG--  178
            VA NI GQN+AAIAAT+AEY EMWAQD   M+ Y  +SA AS L PFT P Q T P+G  
Sbjct  121  VATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLA  180

Query  179  ---PAAAAAATQAAGAGAVADAQAT-LAQLPPGILSDILSALAANADPLTSGLLGIASTL  234
                A   A   A+G  AV  A ++  AQ P  I+  +L  LA  +   T  L+G    +
Sbjct  181  GQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQ-LMG--QLI  237

Query  235  NPQVGSAQPIVIPTPIGELDVIALYI-----------ASIATGSIALAITNTARPWH---  280
            N   G         P G      L++           A+ A  +  L +T     W    
Sbjct  238  NAIFG---------PTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPP  288

Query  281  ---IGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSW  337
               I       GLG   G  LS+            G A   SAG+G A LVG LSVP SW
Sbjct  289  APEIPKSSLGAGLGLRSG--LSA------------GLAHAASAGLGQANLVGDLSVPPSW  334

Query  338  TTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASL  381
             +A P ++L     P  ++S  A P     +PA LL  MAL S+
Sbjct  335  ASATPAVRLVANTLP--ATSLAAAPA--TQIPANLLGQMALGSM  374


>gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895080|gb|EFG74799.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=459

 Score =  187 bits (474),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 158/363 (44%), Positives = 202/363 (56%), Gaps = 49/363 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MD+G+LPPE+NS+RMY+GPG  SML AAAAWD +A EL S A SY +V+S L    W+GP
Sbjct  1    MDYGVLPPEINSARMYAGPGSGSMLTAAAAWDELATELRSIAASYSAVISGLTTA-WLGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++  MAAAA PY  WL ATAA A+++ +QARAAA A+  AFA TVPP ++  NR+ L SL
Sbjct  60   SSTRMAAAAAPYAAWLNATAAQAEQSGSQARAAAAAYEAAFAATVPPPVIETNRAELESL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A N  GQN+AAIAA +A YA MWAQDAA MY Y G SAAA+A+ PF PP Q T PAG A
Sbjct  120  IATNTFGQNTAAIAANEARYARMWAQDAAAMYGYAGQSAAAAAVTPFDPPAQNTNPAGTA  179

Query  181  A-AAAATQAAGAGAVADAQATLAQL---PPGILSDILSALAAN--------------ADP  222
               AA +Q  G  A  ++QA L+ L    P  L  + +  A N                 
Sbjct  180  GQTAAVSQVVGTSAGTNSQAALSHLTSATPSALRSLAAPAAVNPPSASSLASFLSSLNSS  239

Query  223  LTSGLLGIASTLNPQVGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIG  282
              + L G    +   V  A  ++I T      ++ L I +   G + +A+   A P    
Sbjct  240  PLAKLAGNVELIPKAVLPANDVLIST------IMGLVIGARHLGDLTVAV-KAATP----  288

Query  283  LYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
              G A GLG                +  P  G+  VSA VG A LVG L+VP SW  A P
Sbjct  289  --GLAAGLG----------------YAAPALGST-VSATVGQAGLVGGLAVPPSWAVATP  329

Query  343  EIQ  345
             I+
Sbjct  330  AIR  332


>gi|342857520|ref|ZP_08714176.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342134853|gb|EGT88019.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=445

 Score =  186 bits (473),  Expect = 5e-45, Method: Compositional matrix adjust.
 Identities = 185/441 (42%), Positives = 244/441 (56%), Gaps = 59/441 (13%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            M F +LPPEVNS RMY+GPG  S+L+AAAAWD +A+EL +AA +  SV+S L  EPW GP
Sbjct  1    MHFAVLPPEVNSGRMYAGPGAGSLLSAAAAWDELASELHTAAANIESVISGLTAEPWQGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            +AAA AAAA P V WL ATA  A +   QA+AAA A+ +A+A TV PS++AANRS+L SL
Sbjct  61   SAAATAAAAAPQVAWLNATAEQATQAGAQAKAAATAYESAYAATVHPSVIAANRSQLSSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VA N+LGQN+ AIAAT+  Y EMWAQD A MY Y GAS AAS + PFTPP Q T   G A
Sbjct  121  VATNLLGQNTPAIAATEVAYGEMWAQDVAAMYGYAGASQAASQVTPFTPPQQTTNQGGLA  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSAL--AANADPLTSGLLGIASTLNPQV  238
            A  AAT  A   +    Q+ L+      +S + +AL     +   +SGL  ++S +NP  
Sbjct  181  AQTAATTQAAGTSAGRVQSALSG---NAMSAVPNALQSLTTSSTASSGLSDLSSFMNP--  235

Query  239  GSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQ----  294
                           ++++L  A +  G+             IG+ G AG +  T+    
Sbjct  236  --------------YNLVSLGSAFLGNGT-----------GLIGVSGAAGFISDTEHKIV  270

Query  295  --GHPLSSATDEPEP---HWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQ  349
              G  L +A ++PE       P G A  VSAG+G A  +G +SVP  W+TAAPE++L   
Sbjct  271  EPGTKLKAAPEKPEAPAVSRSP-GKATTVSAGMGRANSLGGMSVPQGWSTAAPEVRLTAL  329

Query  350  ATPTFSSSAGADPTALNGMPAGLLSGMA-------LASLAARGTTGGGGTRSGTSTDGQE  402
             +P    +AGA P    G  +GL SG         L +++ RGT    G +   +  G  
Sbjct  330  ESP----AAGAVPAGRAG--SGLFSGQMPLFGGAPLMAMSGRGTPDSRGRQP--AGVGDT  381

Query  403  DGRKPPVVVIREQPPPGNPPR  423
             GR  PV V    P  G P R
Sbjct  382  TGR--PVPVGATAPESGQPQR  400


>gi|57116920|ref|YP_177653.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|38684069|emb|CAE55432.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
Length=399

 Score =  186 bits (472),  Expect = 6e-45, Method: Compositional matrix adjust.
 Identities = 167/360 (47%), Positives = 219/360 (61%), Gaps = 38/360 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            +DF  LPPE+NS+RMYSG G   MLAAA+AW G++AEL ++A+SY SV+STL  E W GP
Sbjct  1    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+A+M AAA PYV W++ TA  A++   QA AAA A+  AFA TVPP ++ ANR++LM+L
Sbjct  61   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A N+LGQN+ AIAAT+A+YAEMW+QDA  MY Y GASAAA+ L PFT PVQ T  +G A
Sbjct  121  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  180

Query  181  AAAAATQAAGAGAVADAQATLAQL---PPGILSDILSALAANADPLTSGLLGIASTLNPQ  237
            A +AA   A   +    Q TL+QL    P +L  + S+ AA      SGLLGI  + +  
Sbjct  181  AQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGSGSSW  240

Query  238  VGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLY-------------  284
            +     +        LD  + +  +IA+  + L  +NT  P+ +GL              
Sbjct  241  LDKLWAL--------LDPNSNFWNTIASSGLFLP-SNTIAPF-LGLLGGVAAADAAGDVL  290

Query  285  --GNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
                +GGLG     PL SA        G  GG   V+AG+G+AA VG LSVP SWT AAP
Sbjct  291  GEATSGGLGGALVAPLGSA--------GGLGGT--VAAGLGNAATVGTLSVPPSWTAAAP  340


>gi|148661613|ref|YP_001283136.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967398|ref|ZP_02549675.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|307084422|ref|ZP_07493535.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|7478807|pir||H70931 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|148505765|gb|ABQ73574.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|308365982|gb|EFP54833.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=403

 Score =  186 bits (472),  Expect = 7e-45, Method: Compositional matrix adjust.
 Identities = 167/360 (47%), Positives = 219/360 (61%), Gaps = 38/360 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            +DF  LPPE+NS+RMYSG G   MLAAA+AW G++AEL ++A+SY SV+STL  E W GP
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            A+A+M AAA PYV W++ TA  A++   QA AAA A+  AFA TVPP ++ ANR++LM+L
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A N+LGQN+ AIAAT+A+YAEMW+QDA  MY Y GASAAA+ L PFT PVQ T  +G A
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  181  AAAAATQAAGAGAVADAQATLAQL---PPGILSDILSALAANADPLTSGLLGIASTLNPQ  237
            A +AA   A   +    Q TL+QL    P +L  + S+ AA      SGLLGI  + +  
Sbjct  185  AQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGSGSSW  244

Query  238  VGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLY-------------  284
            +     +        LD  + +  +IA+  + L  +NT  P+ +GL              
Sbjct  245  LDKLWAL--------LDPNSNFWNTIASSGLFLP-SNTIAPF-LGLLGGVAAADAAGDVL  294

Query  285  --GNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
                +GGLG     PL SA        G  GG   V+AG+G+AA VG LSVP SWT AAP
Sbjct  295  GEATSGGLGGALVAPLGSA--------GGLGGT--VAAGLGNAATVGTLSVPPSWTAAAP  344


>gi|296164997|ref|ZP_06847552.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295899645|gb|EFG79096.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=471

 Score =  186 bits (471),  Expect = 9e-45, Method: Compositional matrix adjust.
 Identities = 156/359 (44%), Positives = 202/359 (57%), Gaps = 29/359 (8%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDF + PPEVNS RMY G G ESM+AAA AW+G+A+EL +AA +Y SV+S L   PW+GP
Sbjct  1    MDFAIFPPEVNSGRMYIGAGSESMVAAAEAWEGLASELHTAANAYQSVISGLTAGPWLGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++A+MAAAA  YVGWL++ A  A+ETA +ARAA  A+  AFA TVPP LVAANR+    L
Sbjct  61   SSASMAAAAASYVGWLSSAAMQAEETAMRARAAVAAYDEAFASTVPPQLVAANRALFARL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            VA N+ GQN++AIA T+ +Y EMWAQDAA MY Y GASAAA+ L PF    Q T P+G  
Sbjct  121  VANNLFGQNTSAIATTETQYVEMWAQDAAAMYGYAGASAAATTLTPFVAAQQNTDPSGSV  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGI--LSDILSALAANADPLTSGLLGIASTLNPQV  238
               AA   A   ++ +AQ  ++ L      + + L   A  A   TS L  +A  ++  V
Sbjct  181  GQTAAVSRAAGTSIGEAQNAVSSLQQSFSAVPNALQGFAVAAPTATSPLNTLADLVSIFV  240

Query  239  G---SAQPIVIPTPIGELDVIAL------YIASIATGSIALAITNTARPWHIGLYGNAGG  289
                    I +  P+  L ++AL      Y   + T  I ++  N  + W         G
Sbjct  241  DLPAGLASIFVDVPLSTLGLVALPFDIGGYYTGVHTDDI-VSGWNGEQSWP--------G  291

Query  290  LGPTQGHPLSSATDEPEPHWGPFGGAAP---VSAGVGHAALVGALSVPHSWTTAAPEIQ  345
             GP    P       P P      G  P   VSAGVG A  VG LSVP +WT A P ++
Sbjct  292  SGPAPVKPF------PAPLLNLRPGTIPPSTVSAGVGEANTVGNLSVPATWTIATPLVR  344


>gi|340626811|ref|YP_004745263.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005001|emb|CCC44149.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=423

 Score =  185 bits (470),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 172/412 (42%), Positives = 214/412 (52%), Gaps = 45/412 (10%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFGLLPPE+NS RMY+GPGP  MLAAA AWDG+A EL + A  Y S +S L    W GP
Sbjct  1    MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSAL-TGAWSGP  59

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++ +MA+AA PYV W++ATA  A+  A QAR A  A+  AFA TVPP ++AANR++LM L
Sbjct  60   SSTSMASAAAPYVAWMSATAVHAELAAAQARLAVAAYEAAFAATVPPPVIAANRAQLMVL  119

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A NI GQN+ AI  T+A+Y EMWAQDAA MY Y G+SA AS +  FT P Q T     +
Sbjct  120  IATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTT---NHS  176

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
               A + A        A   L    P +LS +  AL   A P  S           Q  S
Sbjct  177  QLGAQSSAVAQTVATAAGGNLQSAFPQLLSAVPRALQGLALPTAS-----------QSAS  225

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIAL--AITNTARPWHIGL---------YGNAGG  289
            A P  + T +G L     ++    TG       +  +  P+ +G+          G +  
Sbjct  226  ATPQWV-TDLGNLST---FLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSAL  281

Query  290  LGPTQGHPLSSA---TDEPEPH----WGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAP  342
            LG   G P++ A     E   H         G   VSAG+G A LVG LSVP  WT AAP
Sbjct  282  LGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAP  341

Query  343  EI---QLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGG  391
            EI     A+QAT        A P A       LL GMAL+ LA R   G  G
Sbjct  342  EIPSPAAALQAT-----RLAAAPMAATDGAGALLGGMALSGLAGRAAAGSTG  388


>gi|240171072|ref|ZP_04749731.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=386

 Score =  184 bits (468),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 171/396 (44%), Positives = 218/396 (56%), Gaps = 34/396 (8%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            M F  LPPEVNS RMY+GPG ESML AA+AW+ VA EL + A S  S++  LI  PW+G 
Sbjct  1    MMFASLPPEVNSGRMYTGPGAESMLVAASAWETVAGELYATAASVDSMICGLISGPWLGA  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            +A AMAAAA  YV WL  TAA A++ A QARAA  A+ TA AMTVPP+LVAANR++L SL
Sbjct  61   SATAMAAAAASYVAWLKTTAAQAEQAAAQARAAVAAYLTAHAMTVPPALVAANRAQLESL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA  180
            +A ++LGQN+ AIAAT+A+Y EMWAQDAA MY Y   S AA+ L PFT P + + P+G  
Sbjct  121  IATDVLGQNAPAIAATEAQYGEMWAQDAAAMYCYAAGSTAATTLTPFTAPAEISDPSGQV  180

Query  181  AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS  240
            A  AA   A   +VA              ++I +A+A     + + L GI        G 
Sbjct  181  ANLAALVQATGNSVA--------------TEITNAVAQLTSAVPAALAGIG-------GM  219

Query  241  AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGP-TQGHPLS  299
            A P  +P+ + +L  +     +    S +LA         + +  N  GL P        
Sbjct  220  AAPSALPSWVSDLQTVMSIFGTPFFASTSLAGLG------MSMLSNLKGLFPAAAAAGAQ  273

Query  300  SATDEPEPHWGPFGGA---APVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTF--  354
             AT   +   G    +   A VSAG+G+A  VGALSVP SW   AP    A  A  T   
Sbjct  274  IATSVAQTGTGALTSSSLTAAVSAGLGNATTVGALSVPQSWAATAPVAPAATAAAATPLP  333

Query  355  -SSSAGADPTALNGMPAGLLSGMALASLAARGTTGG  389
             S+ A A        P  LL GM LA L++RG TGG
Sbjct  334  RSALAAAVDVLDAASPGTLLGGMPLAQLSSRGMTGG  369


>gi|31792997|ref|NP_855490.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121637710|ref|YP_977933.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224990194|ref|YP_002644881.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 29 more sequence titles
 Length=409

 Score =  184 bits (466),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 110/177 (63%), Positives = 131/177 (75%), Gaps = 0/177 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPE+NS RMY+GPG   +LAAAAAWD +AAEL SAA SYGS +  L V PWMGP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++  MAAA  PYV W++ TA  A++   QA+ AA  + TAFA TVPP ++ ANR+ LMSL
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPA  177
            VA NI GQN+ AIAAT+A YAEMWAQDAA MY Y G+SA AS L PF+ P Q T P+
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  177


>gi|57116921|ref|YP_177844.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661614|ref|YP_001283137.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148823021|ref|YP_001287775.1| PPE family protein [Mycobacterium tuberculosis F11]
 9 more sequence titles
 Length=409

 Score =  183 bits (465),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 110/177 (63%), Positives = 131/177 (75%), Gaps = 0/177 (0%)

Query  1    MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP  60
            MDFG LPPE+NS RMY+GPG   +LAAAAAWD +AAEL SAA SYGS +  L V PWMGP
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  61   AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL  120
            ++  MAAA  PYV W++ TA  A++   QA+ AA  + TAFA TVPP ++ ANR+ LMSL
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  121  VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPA  177
            VA NI GQN+ AIAAT+A YAEMWAQDAA MY Y G+SA AS L PF+ P Q T P+
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  177



Lambda     K      H
   0.312    0.126    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 859091811192




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40