BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0939 Length=644 Score E Sequences producing significant alignments: (Bits) Value gi|15608079|ref|NP_215454.1| bifunctional 2-hydroxyhepta-2,4-die... 1300 0.0 gi|289573569|ref|ZP_06453796.1| bifunctional 2-hydroxyhepta-2,4-... 1297 0.0 gi|340625948|ref|YP_004744400.1| putative bifunctional enzyme: 2... 1291 0.0 gi|289744670|ref|ZP_06504048.1| conserved hypothetical protein [... 1137 0.0 gi|240171921|ref|ZP_04750580.1| putative 2-hydroxyhepta-2,4-dien... 1079 0.0 gi|183984541|ref|YP_001852832.1| bifunctional enzyme: 2-hydroxyh... 1056 0.0 gi|118462680|ref|YP_880312.1| fumarylacetoacetate hydrolase, put... 1048 0.0 gi|41406979|ref|NP_959815.1| hypothetical protein MAP0881 [Mycob... 1044 0.0 gi|342860543|ref|ZP_08717194.1| fumarylacetoacetate hydrolase, p... 1041 0.0 gi|254819345|ref|ZP_05224346.1| fumarylacetoacetate hydrolase fa... 1036 0.0 gi|296169693|ref|ZP_06851311.1| bifunctional 2-hydroxyhepta-2,4-... 1022 0.0 gi|271970244|ref|YP_003344440.1| 2-keto-4-pentenoate hydratase/2... 783 0.0 gi|336461445|gb|EGO40316.1| 2-keto-4-pentenoate hydratase/2-oxoh... 763 0.0 gi|333989522|ref|YP_004522136.1| 2-hydroxyhepta-24-diene-17-dioa... 466 4e-129 gi|325003078|ref|ZP_08124190.1| hypothetical protein PseP1_30125... 306 1e-80 gi|336461303|gb|EGO40175.1| 2-keto-4-pentenoate hydratase/2-oxoh... 285 2e-74 gi|325003079|ref|ZP_08124191.1| beta-lactamase domain protein [P... 272 1e-70 gi|254389627|ref|ZP_05004853.1| conserved hypothetical protein [... 265 2e-68 gi|294816896|ref|ZP_06775538.1| 2-keto-4-pentenoate hydratase/2-... 259 8e-67 gi|312194315|ref|YP_004014376.1| fumarylacetoacetate (FAA) hydro... 259 1e-66 gi|302530409|ref|ZP_07282751.1| predicted protein [Streptomyces ... 256 7e-66 gi|154252104|ref|YP_001412928.1| beta-lactamase domain-containin... 253 1e-64 gi|114798378|ref|YP_762133.1| metallo-beta-lactamase family prot... 251 2e-64 gi|262197714|ref|YP_003268923.1| beta-lactamase [Haliangium ochr... 249 9e-64 gi|289208218|ref|YP_003460284.1| beta-lactamase [Thioalkalivibri... 248 2e-63 gi|284042591|ref|YP_003392931.1| beta-lactamase [Conexibacter wo... 244 3e-62 gi|331698695|ref|YP_004334934.1| fumarylacetoacetate (FAA) hydro... 239 9e-61 gi|162453541|ref|YP_001615908.1| beta-lactamase [Sorangium cellu... 238 2e-60 gi|297196822|ref|ZP_06914219.1| beta-lactamase [Streptomyces svi... 238 2e-60 gi|254389628|ref|ZP_05004854.1| beta-lactamase [Streptomyces cla... 238 2e-60 gi|294816897|ref|ZP_06775539.1| bifunctional 2-hydroxyhepta-2,4-... 236 9e-60 gi|297204670|ref|ZP_06922067.1| hydroxylase [Streptomyces sviceu... 234 3e-59 gi|88811790|ref|ZP_01127044.1| hypothetical protein NB231_05275 ... 233 1e-58 gi|297196820|ref|ZP_06914217.1| hydroxylase [Streptomyces sviceu... 232 1e-58 gi|108805050|ref|YP_644987.1| fumarylacetoacetate (FAA) hydrolas... 231 4e-58 gi|148254097|ref|YP_001238682.1| putative fumarylacetoacetate (F... 231 4e-58 gi|84687095|ref|ZP_01014977.1| hypothetical protein 109945700026... 227 5e-57 gi|290963330|ref|YP_003494512.1| hydroxylase [Streptomyces scabi... 225 2e-56 gi|334140774|ref|YP_004533980.1| metallo-beta-lactamase family p... 224 3e-56 gi|254483370|ref|ZP_05096600.1| metallo-beta-lactamase domain pr... 224 4e-56 gi|21224621|ref|NP_630400.1| hydroxylase [Streptomyces coelicolo... 224 5e-56 gi|345137925|dbj|BAK67534.1| putative hydrolase [Sphingobium sp.... 218 2e-54 gi|345012276|ref|YP_004814630.1| fumarylacetoacetate (FAA) hydro... 218 3e-54 gi|289768061|ref|ZP_06527439.1| hydroxylase [Streptomyces livida... 218 3e-54 gi|334142644|ref|YP_004535852.1| beta-lactamase domain-containin... 212 1e-52 gi|149181234|ref|ZP_01859733.1| fumarylacetoacetate hydrolase fa... 211 2e-52 gi|297203287|ref|ZP_06920684.1| hydroxylase [Streptomyces sviceu... 211 2e-52 gi|229009731|ref|ZP_04166954.1| Fumarylacetoacetate hydrolase [B... 210 5e-52 gi|126348270|emb|CAJ89991.1| putative hydroxylase [Streptomyces ... 210 7e-52 gi|163938232|ref|YP_001643116.1| fumarylacetoacetate (FAA) hydro... 210 8e-52 >gi|15608079|ref|NP_215454.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium tuberculosis H37Rv] gi|15840362|ref|NP_335399.1| fumarylacetoacetate hydrolase family/metallo-beta-lactamase superfamily protein [Mycobacterium tuberculosis CDC1551] gi|31792128|ref|NP_854621.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=644 Score = 1300 bits (3365), Expect = 0.0, Method: Compositional matrix adjust. Identities = 644/644 (100%), Positives = 644/644 (100%), Gaps = 0/644 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD Sbjct 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD Sbjct 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI Sbjct 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR Sbjct 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 Query 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL Sbjct 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 Query 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI Sbjct 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 Query 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL Sbjct 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 Query 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD Sbjct 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 Query 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA Sbjct 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 Query 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT Sbjct 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 >gi|289573569|ref|ZP_06453796.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium tuberculosis K85] gi|339631001|ref|YP_004722643.1| bifunctional protein: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ cyclase/dehydrase [Mycobacterium africanum GM041182] gi|289538000|gb|EFD42578.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium tuberculosis K85] gi|339330357|emb|CCC26020.1| putative bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase [Mycobacterium africanum GM041182] Length=644 Score = 1297 bits (3356), Expect = 0.0, Method: Compositional matrix adjust. Identities = 643/644 (99%), Positives = 643/644 (99%), Gaps = 0/644 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD Sbjct 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD Sbjct 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI Sbjct 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR Sbjct 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 Query 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLP GGYGFSNAGL Sbjct 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPVGGYGFSNAGL 360 Query 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI Sbjct 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 Query 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL Sbjct 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 Query 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD Sbjct 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 Query 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA Sbjct 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 Query 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT Sbjct 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 >gi|340625948|ref|YP_004744400.1| putative bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/cyclase/dehydrase [Mycobacterium canettii CIPT 140010059] gi|340004138|emb|CCC43276.1| putative bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase [Mycobacterium canettii CIPT 140010059] Length=644 Score = 1291 bits (3341), Expect = 0.0, Method: Compositional matrix adjust. Identities = 639/644 (99%), Positives = 642/644 (99%), Gaps = 0/644 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERA+RSPAAVVALD Sbjct 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERALRSPAAVVALD 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD Sbjct 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRV ALVNGTVIGSGSTAQMDWSFGEVI Sbjct 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVTALVNGTVIGSGSTAQMDWSFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR Sbjct 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 Query 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL Sbjct 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 Query 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI Sbjct 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 Query 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 IAAKGTSEEIEHGPAPEMLARIQTAD+GPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL Sbjct 421 IAAKGTSEEIEHGPAPEMLARIQTADVGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 Query 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 AIELGGRRVDLLNLGPAHTTADSVVHV DAGVLFAGDLLFIGCTPIVWAGPIA+WVAACD Sbjct 481 AIELGGRRVDLLNLGPAHTTADSVVHVPDAGVLFAGDLLFIGCTPIVWAGPIASWVAACD 540 Query 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA Sbjct 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 Query 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT Sbjct 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHCT 644 >gi|289744670|ref|ZP_06504048.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987] gi|289685198|gb|EFD52686.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987] Length=561 Score = 1137 bits (2940), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/561 (100%), Positives = 561/561 (100%), Gaps = 0/561 (0%) Query 84 MRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGT 143 MRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGT Sbjct 1 MRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGT 60 Query 144 SGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELE 203 SGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELE Sbjct 61 SGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELE 120 Query 204 PYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTC 263 PYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTC Sbjct 121 PYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTC 180 Query 264 TLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVRTSGTPFPLALRPNPDAEPDRRGV 323 TLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVRTSGTPFPLALRPNPDAEPDRRGV Sbjct 181 TLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVRTSGTPFPLALRPNPDAEPDRRGV 240 Query 324 NPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREML 383 NPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREML Sbjct 241 NPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREML 300 Query 384 AAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQ 443 AAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQ Sbjct 301 AAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQ 360 Query 444 TADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADS 503 TADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADS Sbjct 361 TADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADS 420 Query 504 VVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGI 563 VVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGI Sbjct 421 VVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGI 480 Query 564 RAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDT 623 RAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDT Sbjct 481 RAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDT 540 Query 624 PRQDLLALLVMQAEWAARHCT 644 PRQDLLALLVMQAEWAARHCT Sbjct 541 PRQDLLALLVMQAEWAARHCT 561 >gi|240171921|ref|ZP_04750580.1| putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Mycobacterium kansasii ATCC 12478] Length=642 Score = 1079 bits (2790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/641 (84%), Positives = 572/641 (90%), Gaps = 0/641 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTYRSD GER GVLSGD IYA+PP +LLDL+G GADGLRTAGE A+R+PAAVV L Sbjct 1 MKWVTYRSDDGERAGVLSGDTIYALPPGSALLDLLGGGADGLRTAGEAALRAPAAVVGLA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V+L APIPRPPSIRDSLCFLDHMRNCQ+AMGGGRVL DTWYRIPAFYFACP+TVLGPYD Sbjct 61 DVSLTAPIPRPPSIRDSLCFLDHMRNCQQAMGGGRVLADTWYRIPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGT G DLTVEQAE+SI+GYTIFNDWSARDLQMLEGQLRI Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGTDLTVEQAEQSIVGYTIFNDWSARDLQMLEGQLRI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSG+TLGPYLVTPDELEPY RGG+L L+V ALVN TVIG+GST MDW+FGEVI Sbjct 181 GQAKGKDSGVTLGPYLVTPDELEPYRRGGRLHLQVTALVNDTVIGTGSTGAMDWTFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 +YASRGV L PGDVFGSGTVPTCTLVEHL ESFPGWLH+GDVVTL+ EGLGETRQTVR Sbjct 241 SYASRGVLLRPGDVFGSGTVPTCTLVEHLGDLESFPGWLHEGDVVTLRAEGLGETRQTVR 300 Query 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 S P PL R NPDA P R VN AP RVP+TRGLHEVADRVWAWTLPDGGYG+SNAGL Sbjct 301 VSKPPHPLMPRRNPDAPPARARVNRAPARVPYTRGLHEVADRVWAWTLPDGGYGWSNAGL 360 Query 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 VAGDGASLLVDTLFDLALTREML AMKP+T+RAPITDALITHSNGDHTHG QLLD SVRI Sbjct 361 VAGDGASLLVDTLFDLALTREMLDAMKPITDRAPITDALITHSNGDHTHGNQLLDPSVRI 420 Query 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 IAA+GT+EEI HG PEMLAR+QTADLGPVAT Y RDRFGHF F GI +RNAD TF+R L Sbjct 421 IAAQGTAEEIAHGMHPEMLARLQTADLGPVATGYARDRFGHFGFGGITVRNADQTFERQL 480 Query 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 IE+GGRRV+LLNLGPAHT ADSVVHV +AGVLFAGDLLFIGCTPIVW+GPI NW+AACD Sbjct 481 TIEVGGRRVELLNLGPAHTAADSVVHVPEAGVLFAGDLLFIGCTPIVWSGPIENWIAACD 540 Query 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 AMIAL+ VVPGHGPVT DGIRAVRGYL HI+EQAEAAYRKGLS EAV+ IDLGEYA Sbjct 541 AMIALEPSVVVPGHGPVTDSDGIRAVRGYLVHISEQAEAAYRKGLSFVEAVDIIDLGEYA 600 Query 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 +WLDSERVVVN+YQRYRELDP TPRQ+LL LL MQAEW A Sbjct 601 TWLDSERVVVNIYQRYRELDPATPRQELLGLLTMQAEWLAN 641 >gi|183984541|ref|YP_001852832.1| bifunctional enzyme: 2-hydroxyhepta-2,4-diene- 1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase [Mycobacterium marinum M] gi|183177867|gb|ACC42977.1| bifunctional enzyme: 2-hydroxyhepta-2,4-diene- 1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase [Mycobacterium marinum M] Length=643 Score = 1056 bits (2732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 518/643 (81%), Positives = 568/643 (89%), Gaps = 0/643 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTYRS GER GVLS +IYAM P V+LLDL+ RGADGLR AGE +RSP+ VVALD Sbjct 1 MKWVTYRSADGERVGVLSDGSIYAMAPGVALLDLIKRGADGLREAGENVLRSPSEVVALD 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEA+GGGRVLMDTWYRIPAFYFACP+TVLGPYD Sbjct 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAVGGGRVLMDTWYRIPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAP APGSAWQDFELEIAAVIGT G+DL+VEQAE+SIIGYTIFNDWSARDLQ LEGQLRI Sbjct 121 DAPMAPGSAWQDFELEIAAVIGTGGQDLSVEQAEQSIIGYTIFNDWSARDLQQLEGQLRI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSG+TLGPYLVT DEL+ Y R GKLSL+V ALVN TVIGSGSTA MDW+FGEVI Sbjct 181 GQAKGKDSGVTLGPYLVTADELQAYRRDGKLSLQVSALVNDTVIGSGSTATMDWTFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQTVR 300 +Y SRGV L PGDV GSGTVPTCTLVEHL P+SFPGWL DGDVVTL+VEGLG+TRQ V Sbjct 241 SYVSRGVMLAPGDVIGSGTVPTCTLVEHLTNPDSFPGWLRDGDVVTLEVEGLGQTRQRVC 300 Query 301 TSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGL 360 + P PLA R +P+A P+ VNPAP VP+TRGLH+VADRVWAWTLPDGG+G+SNAGL Sbjct 301 ATPPPQPLAPRVDPNAAPEAARVNPAPPLVPYTRGLHQVADRVWAWTLPDGGFGWSNAGL 360 Query 361 VAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRI 420 VAGDGASLLVDTLFDLALTREML AM+P+T+ APITDALITHSNGDHTHG QLL SVRI Sbjct 361 VAGDGASLLVDTLFDLALTREMLDAMRPITDAAPITDALITHSNGDHTHGNQLLSPSVRI 420 Query 421 IAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDL 480 IAAKGT+EEI P +L +QT DLGPVATR++RDRFGHFDFSGI+LRNAD TFD +L Sbjct 421 IAAKGTAEEIAEDTGPTLLTAMQTIDLGPVATRFMRDRFGHFDFSGIRLRNADQTFDHEL 480 Query 481 AIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACD 540 I++GGRRVDL+NLGPAHT ADSVVHV DAGVLFAGDLLFIGCTPIVW GPIANW+AACD Sbjct 481 TIDVGGRRVDLINLGPAHTAADSVVHVPDAGVLFAGDLLFIGCTPIVWNGPIANWIAACD 540 Query 541 AMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYA 600 AMIALDAP VVPGHGPVT PDGIRAVRGY H+ EQAEAAYRKGLSL EA+ET++LG+YA Sbjct 541 AMIALDAPIVVPGHGPVTDPDGIRAVRGYFEHVNEQAEAAYRKGLSLAEAIETVELGDYA 600 Query 601 SWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAARHC 643 +WLDSER+VVN+YQRYRELDP TP + LALLVMQAEWAA+ Sbjct 601 AWLDSERIVVNIYQRYRELDPHTPEVERLALLVMQAEWAAKRV 643 >gi|118462680|ref|YP_880312.1| fumarylacetoacetate hydrolase, putative [Mycobacterium avium 104] gi|254773939|ref|ZP_05215455.1| fumarylacetoacetate hydrolase family protein, putative [Mycobacterium avium subsp. avium ATCC 25291] gi|118163967|gb|ABK64864.1| fumarylacetoacetate hydrolase family protein, putative [Mycobacterium avium 104] Length=645 Score = 1048 bits (2709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 528/643 (83%), Positives = 565/643 (88%), Gaps = 2/643 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY+ D GER GVL D IYAM V+LLDL+ RGA+GLR AGE A RSPAA V Sbjct 1 MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 L APIPRPPSIRDSLCFLDHMRNCQ A+G GRVL DTWYR+PAFYFACP+TVLGPYD Sbjct 61 RARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGT GKDL+VEQAE++IIGYTIFNDWSARDLQ L+ QL I Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGYTIFNDWSARDLQQLDSQLGI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSG+TLGPYLVTPDELEPY R GKL LRV A VN TVIGSGSTAQMDW+FGEVI Sbjct 181 GQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQT 298 +YASRGVTL PGDV GSGTVPTCTLVEHL P ESFPGWLHDGDVVTL+VEGLGETRQT Sbjct 241 SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT 300 Query 299 VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNA 358 VR SG P PLA RPNPDA P VN A RVP+TRGLH+V DRVWAWTLPDGGYG+SNA Sbjct 301 VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNA 360 Query 359 GLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSV 418 GL+AGDGASLLVDTLFDLALTREML AM+P+T APITDA+ITHSNGDHTHG QLLD +V Sbjct 361 GLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITDAVITHSNGDHTHGNQLLDPAV 420 Query 419 RIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDR 478 RIIAA GT+EEI HG APEMLA QTA+LGPVATRY R+RFGHFDFS I LRNAD TFDR Sbjct 421 RIIAAHGTAEEIAHGMAPEMLAMAQTANLGPVATRYTRERFGHFDFSNITLRNADETFDR 480 Query 479 DLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAA 538 LA+E+GGRRVD+LNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGPIANWVAA Sbjct 481 SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAA 540 Query 539 CDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGE 598 CDAMIALDAPTVVPGHGPVT PDGIRAVRGYL HIAEQAEAAYRKGLS PEA +TIDLGE Sbjct 541 CDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWPEAADTIDLGE 600 Query 599 YASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 YA+WLD+ERVVVNVYQRYRELDP TP+ +++ALLVMQAEW A+ Sbjct 601 YATWLDAERVVVNVYQRYRELDPHTPQLEVMALLVMQAEWLAK 643 >gi|41406979|ref|NP_959815.1| hypothetical protein MAP0881 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395330|gb|AAS03198.1| hypothetical protein MAP_0881 [Mycobacterium avium subsp. paratuberculosis K-10] Length=645 Score = 1044 bits (2700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 528/643 (83%), Positives = 562/643 (88%), Gaps = 2/643 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY+ D GER GVL D IYAM V+LLDL+ RGA+GLR AGE A RSPAA V Sbjct 1 MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 L APIPRPPSIRDSLCFLDHMRNCQ A+G GRVL DTWYR+PAFYFACP+TVLGPYD Sbjct 61 RARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGT GKDL+VEQAE++IIGYTIFNDWSARDLQ L+ QL I Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGYTIFNDWSARDLQQLDSQLGI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKDSG+TLGPYLVTPDELEPY R GKL LRV A VN TVIGSGSTAQMDW+FGEVI Sbjct 181 GQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQT 298 +YASRGVTL PGDV GSGTVPTCTLVEHL P ESFPGWLHDGDVVTL+VEGLGETRQT Sbjct 241 SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT 300 Query 299 VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNA 358 VR SG P PLA RPNPDA P VN A RVP+TRGLH+V DRVWAWTLPDGGYG+SNA Sbjct 301 VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNA 360 Query 359 GLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSV 418 GL+AGDGASLLVDTLFDLALTREML AM+P+T APIT A+ITHSNGDHTHG QLLD +V Sbjct 361 GLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKAVITHSNGDHTHGNQLLDPAV 420 Query 419 RIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDR 478 RIIAA GT+EEI HG APEMLA QTADLGPVATRY R+RFGHFDFS I LRNAD TFDR Sbjct 421 RIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR 480 Query 479 DLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAA 538 LA+E+GGRRVD+LNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGPIANWVAA Sbjct 481 SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAA 540 Query 539 CDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGE 598 CDAMIALDAPTVVPGHGPVT PDGIRAVRGYL HIAEQAEAAYRKGLS EA +TIDLGE Sbjct 541 CDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGE 600 Query 599 YASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 YA+WLD+ERVVVNVYQRYRELDP TP+ + +ALLVMQAEW AR Sbjct 601 YATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEWLAR 643 >gi|342860543|ref|ZP_08717194.1| fumarylacetoacetate hydrolase, putative [Mycobacterium colombiense CECT 3035] gi|342132198|gb|EGT85439.1| fumarylacetoacetate hydrolase, putative [Mycobacterium colombiense CECT 3035] Length=649 Score = 1041 bits (2692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/646 (81%), Positives = 565/646 (88%), Gaps = 5/646 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY+ D GER GV+SGD I+ +P V+LL+L+ RG DGLR AGE A RSPA V L Sbjct 1 MKWVTYQGDDGERVGVVSGDTIHPLPAGVTLLELIARGHDGLRQAGEEARRSPAGTVPLA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V L APIPRPPSIRDSLCFLDHMRNCQ A+G GRVL D+WYRIPAFYFACP+TVLGPYD Sbjct 61 DVRLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADSWYRIPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGT GKDLTVEQAER+IIGYTIFNDWSARDLQ +E QL I Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGKDLTVEQAERAIIGYTIFNDWSARDLQQMESQLGI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRG---GKLSLRVIALVNGTVIGSGSTAQMDWSFG 237 GQ KGKDSG+TLGPYLVTPDELE Y GKL LRV ALVN VIG+GSTAQMDW+FG Sbjct 181 GQGKGKDSGVTLGPYLVTPDELEQYRHASDRGKLDLRVTALVNDAVIGTGSTAQMDWTFG 240 Query 238 EVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGET 295 EVI+YASRGVTL PGDV GSGTVPTCTLVEHL P ESFPGWLHDGDVVTLQV+GLGET Sbjct 241 EVISYASRGVTLHPGDVIGSGTVPTCTLVEHLNPAALESFPGWLHDGDVVTLQVQGLGET 300 Query 296 RQTVRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGF 355 RQTVR SG PF LA RPNPDA VN AP RVP+TRGLH+V DRVWAWTLPDGGYG+ Sbjct 301 RQTVRASGAPFALAARPNPDAPAAAPRVNRAPARVPYTRGLHQVGDRVWAWTLPDGGYGW 360 Query 356 SNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLD 415 SNAGLVAGDGASLLVDTLFDLALTREML AM+PVT APITDA+ITHSNGDHTHG QLLD Sbjct 361 SNAGLVAGDGASLLVDTLFDLALTREMLTAMRPVTGSAPITDAVITHSNGDHTHGNQLLD 420 Query 416 RSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLT 475 SVRIIAA GT+EEIEHG APEMLA QTA+LGPVAT Y RDRFGHFDFS I LRNAD T Sbjct 421 TSVRIIAAHGTAEEIEHGMAPEMLAMAQTANLGPVATPYTRDRFGHFDFSNITLRNADQT 480 Query 476 FDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANW 535 F+R+L++E+GGRR+D+LNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGPIANW Sbjct 481 FERNLSVEVGGRRIDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANW 540 Query 536 VAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETID 595 VAACDAMIALDAPTVVPGHGPVT PDGIRAVRGYL H+AEQAEAAYR+GLS EA +TID Sbjct 541 VAACDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHVAEQAEAAYRRGLSWAEAADTID 600 Query 596 LGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 LGEYA+WLD+ERVVVNVYQRYRELDP TP+ +++ALLVMQAEW A+ Sbjct 601 LGEYATWLDAERVVVNVYQRYRELDPQTPQLEVMALLVMQAEWFAK 646 >gi|254819345|ref|ZP_05224346.1| fumarylacetoacetate hydrolase family protein, putative [Mycobacterium intracellulare ATCC 13950] Length=634 Score = 1036 bits (2680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 514/633 (82%), Positives = 555/633 (88%), Gaps = 5/633 (0%) Query 16 VLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALDEVTLAAPIPRPPSIR 75 ++SGD IYAMPP V+LLDLV RG++GLR AG+ A RSPAAV L V L APIPRPPSIR Sbjct 1 MVSGDTIYAMPPGVTLLDLVARGSEGLRQAGQDAQRSPAAVAPLAGVRLLAPIPRPPSIR 60 Query 76 DSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFEL 135 DSLCFLDHMRNCQ A+G GR L D+WYRIPAFYFACP+TVLGPYDDAPTAPGSAWQDFEL Sbjct 61 DSLCFLDHMRNCQAALGAGRTLGDSWYRIPAFYFACPATVLGPYDDAPTAPGSAWQDFEL 120 Query 136 EIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPY 195 EIAAVIGT GKDLTVE+AE++IIGYTIFNDWSARDLQ +E QL IGQ KGKDSG+TLGPY Sbjct 121 EIAAVIGTGGKDLTVEEAEQAIIGYTIFNDWSARDLQQMESQLGIGQGKGKDSGVTLGPY 180 Query 196 LVTPDELEPY---CRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLTPG 252 LVTPDELEPY G+L LRV ALVN VIGSGSTAQMDW+FGEVI+YASRGVTL PG Sbjct 181 LVTPDELEPYRHPSYPGRLDLRVTALVNDVVIGSGSTAQMDWTFGEVISYASRGVTLAPG 240 Query 253 DVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQTVRTSGTPFPLAL 310 DV GSGTVPTCTLVEHL P ESFPGWLHDGD+VTLQVEGLGETRQTVR SG P PLA Sbjct 241 DVIGSGTVPTCTLVEHLNPAALESFPGWLHDGDIVTLQVEGLGETRQTVRASGAPHPLAA 300 Query 311 RPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLV 370 RPN DA P VNPA RVP+TRGLHEV RVWAWTLPDGGYG+SNAGL+AGDGASLLV Sbjct 301 RPNSDAAPAPPRVNPARARVPYTRGLHEVGGRVWAWTLPDGGYGWSNAGLIAGDGASLLV 360 Query 371 DTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEI 430 DTLFDLALTREML AM+P+T APITDA+ITHSNGDHTHG QLLD SVRIIAA+GT+EEI Sbjct 361 DTLFDLALTREMLTAMRPLTASAPITDAVITHSNGDHTHGNQLLDPSVRIIAARGTAEEI 420 Query 431 EHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVD 490 EHG APEMLA QTA+LGPVAT Y R+RFGHFDFS IKLRNAD TFDR+LA+E+GGRR+D Sbjct 421 EHGMAPEMLAMAQTANLGPVATPYTRERFGHFDFSNIKLRNADQTFDRNLAVEVGGRRID 480 Query 491 LLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTV 550 +LNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTV Sbjct 481 VLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTV 540 Query 551 VPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVV 610 VPGHGPVT PDGIRAVRGYL H+AEQAEAAY KGLS EA +TIDLGEYASWLD+ERVVV Sbjct 541 VPGHGPVTDPDGIRAVRGYLMHVAEQAEAAYHKGLSWAEAADTIDLGEYASWLDAERVVV 600 Query 611 NVYQRYRELDPDTPRQDLLALLVMQAEWAARHC 643 NVYQRYRELDP TP+ +++ LLVMQAEW A+ Sbjct 601 NVYQRYRELDPQTPQLEVMGLLVMQAEWLAKRA 633 >gi|296169693|ref|ZP_06851311.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895690|gb|EFG75386.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=645 Score = 1022 bits (2642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/643 (81%), Positives = 561/643 (88%), Gaps = 2/643 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY ERTGVLSGD I+AMP V+LLDLV RGADGLR AGE A+R+PA V + Sbjct 1 MKWVTYLGAGAERTGVLSGDTIHAMPAGVTLLDLVARGADGLRAAGEEALRAPAEAVPVA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 V L APIPRPPSIRDSLCFLDHMRNCQ A+G GR L DTWYRIPAFYFACP+TVLGPYD Sbjct 61 AVRLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRALADTWYRIPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGSAWQDFELEIAAVIGT G+DL+VE+AER++IGYTIFNDWSARDLQ +E QL I Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGRDLSVEEAERAVIGYTIFNDWSARDLQQMESQLGI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQ KGKDSG+TLGPYLVTPDELEPY R G L L+V ALVN TVIGSGSTAQMDWSFGEVI Sbjct 181 GQGKGKDSGVTLGPYLVTPDELEPYRRDGGLDLQVTALVNDTVIGSGSTAQMDWSFGEVI 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQT 298 +YASRGVTL PGDV GSGTVPTCTLVEHL +SFPGWLHDGDVVTL+V+GLGETRQT Sbjct 241 SYASRGVTLVPGDVVGSGTVPTCTLVEHLDAAALDSFPGWLHDGDVVTLRVQGLGETRQT 300 Query 299 VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNA 358 VR S P PLA RPNPDA P R VN AP +VP+TRGLH V DRVWAWTLPDGGYG+SNA Sbjct 301 VRASPAPHPLAARPNPDAAPAARRVNRAPAKVPYTRGLHPVGDRVWAWTLPDGGYGWSNA 360 Query 359 GLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSV 418 GLV GDGASLLVDTLFDLALTREML+AM+ +T APITDALITHSNGDHTHG QLLD SV Sbjct 361 GLVTGDGASLLVDTLFDLALTREMLSAMRDITSSAPITDALITHSNGDHTHGNQLLDASV 420 Query 419 RIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDR 478 RIIAA+GT+EEI HG APEMLA QTA+LGPVAT Y RDRF HFDFSGI +RNAD TFDR Sbjct 421 RIIAARGTAEEIAHGMAPEMLAMAQTANLGPVATPYTRDRFQHFDFSGITVRNADQTFDR 480 Query 479 DLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAA 538 +L IE+GGRRV LLNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGPIANW+AA Sbjct 481 ELTIEVGGRRVALLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWIAA 540 Query 539 CDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGE 598 CD MIALDAPTVVPGHGPV+ PDGIRAVRGYL H++EQAEAAYR+GLS +A +TIDLGE Sbjct 541 CDTMIALDAPTVVPGHGPVSDPDGIRAVRGYLTHVSEQAEAAYRRGLSWSDAADTIDLGE 600 Query 599 YASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 YA+WLD+ERVVVNVYQRYRELDP TP+ +++ALLVMQAEW A+ Sbjct 601 YATWLDAERVVVNVYQRYRELDPATPQLEVMALLVMQAEWLAK 643 >gi|271970244|ref|YP_003344440.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway)-like protein [Streptosporangium roseum DSM 43021] gi|270513419|gb|ACZ91697.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway)-like protein [Streptosporangium roseum DSM 43021] Length=637 Score = 783 bits (2022), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/642 (64%), Positives = 485/642 (76%), Gaps = 10/642 (1%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 M++VTY ++ G+R GVL GD I+A PP +LL L+ GLR AGE+A+ P VV L Sbjct 1 MRFVTYAAEDGDRAGVLDGDLIHAFPPGTTLLGLL---GSGLRQAGEQALAEPDEVVPLS 57 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V + APIPRPPSIRD LCFLDHMR C +A GG L TWY+IPAFYFA P+TV+GP+D Sbjct 58 DVMVRAPIPRPPSIRDCLCFLDHMRGCLKATGGTGDLEPTWYQIPAFYFANPATVIGPHD 117 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 D P +PGSAW DFELEI AVIGT+G+DLT EQAE I GYT+ DWSARDLQ LE QL+I Sbjct 118 DVPISPGSAWFDFELEIGAVIGTAGRDLTPEQAEEHIAGYTLMCDWSARDLQGLESQLKI 177 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQAKGKD TLGP+LVTPDEL L++ V A VNG +G G MDWSFGEVI Sbjct 178 GQAKGKDGATTLGPWLVTPDELP-----AGLAVAVRAEVNGVTVGEGRADAMDWSFGEVI 232 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPE--SFPGWLHDGDVVTLQVEGLGETRQT 298 +YASRG L PGDVFGSGTVP C L+EHL + +FPGWL DGDVV L EGLGE RQT Sbjct 233 SYASRGAELQPGDVFGSGTVPGCCLIEHLSFADLAAFPGWLKDGDVVRLSAEGLGEIRQT 292 Query 299 VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNA 358 R S P+PLA RP+P A P R NPAP+ +P+T GLH+V + VWAW LPDGGYG SNA Sbjct 293 ARASAAPYPLAARPDPAAGPRRPRRNPAPSALPYTAGLHQVGEGVWAWLLPDGGYGRSNA 352 Query 359 GLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSV 418 GLV G+GASLLVDTL+DL+LT EML M+ VT+R P+T A++TH++GDHTHG LL V Sbjct 353 GLVTGEGASLLVDTLYDLSLTGEMLDGMRVVTDRHPLTHAVLTHADGDHTHGGGLLPAQV 412 Query 419 RIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDR 478 R+I A+GT+ + PE+ A +Q DLGPV T Y+R+RFG FDF GI+LR D TF R Sbjct 413 RVITAEGTAHGMRTEMPPELTAALQVMDLGPVLTPYMRERFGGFDFGGIRLREPDQTFQR 472 Query 479 DLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAA 538 L +++GGR V LL+LGPAHT AD+VVHV DAGVLFAGDLLFIGCTPIVW+GPIANW++A Sbjct 473 RLTLDVGGREVRLLDLGPAHTEADTVVHVPDAGVLFAGDLLFIGCTPIVWSGPIANWISA 532 Query 539 CDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGE 598 CD M+ALDAPTVVPGHGPVT PDGIRAVR YLAH+ EQA+ A+ KGL+L EA DL + Sbjct 533 CDTMLALDAPTVVPGHGPVTDPDGIRAVRAYLAHVVEQADLAHAKGLNLREAAFAADLAD 592 Query 599 YASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAA 640 YASWLD+ER+VVN+Y+RYRE+DP+ P D AL + AEW A Sbjct 593 YASWLDAERIVVNIYRRYREIDPEQPVLDRFALFALMAEWEA 634 >gi|336461445|gb|EGO40316.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase [Mycobacterium avium subsp. paratuberculosis S397] Length=472 Score = 763 bits (1971), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/470 (83%), Positives = 415/470 (89%), Gaps = 2/470 (0%) Query 174 LEGQLRIGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMD 233 ++ QL IGQAKGKDSG+TLGPYLVTPDELEPY R GKL LRV A VN TVIGSGSTAQMD Sbjct 1 MDSQLGIGQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMD 60 Query 234 WSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEG 291 W+FGEVI+YASRGVTL PGDV GSGTVPTCTLVEHL P ESFPGWLHDGDVVTL+VEG Sbjct 61 WTFGEVISYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEG 120 Query 292 LGETRQTVRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTLPDG 351 LGETRQTVR SG P PLA RPNPDA P VN A RVP+TRGLH+V DRVWAWTLPDG Sbjct 121 LGETRQTVRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDG 180 Query 352 GYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGT 411 GYG+SNAGL+AGDGASLLVDTLFDLALTREML AM+P+T APIT A+ITHSNGDHTHG Sbjct 181 GYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKAVITHSNGDHTHGN 240 Query 412 QLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRN 471 QLLD +VRIIAA GT+EEI HG APEMLA QTADLGPVATRY R+RFGHFDFS I LRN Sbjct 241 QLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRN 300 Query 472 ADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGP 531 AD TFDR LA+E+GGRRVD+LNLGPAHT ADSVVHV DAGVLF GDLLFIGCTPIVWAGP Sbjct 301 ADETFDRSLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGP 360 Query 532 IANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAV 591 IANWVAACDAMIALDAPTVVPGHGPVT PDGIRAVRGYL HIAEQAEAAYRKGLS EA Sbjct 361 IANWVAACDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAA 420 Query 592 ETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEWAAR 641 +TIDLGEYA+WLD+ERVVVNVYQRYRELDP TP+ + +ALLVMQAEW AR Sbjct 421 DTIDLGEYATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEWLAR 470 >gi|333989522|ref|YP_004522136.1| 2-hydroxyhepta-24-diene-17-dioate isomerase [Mycobacterium sp. JDM601] gi|333485491|gb|AEF34883.1| 2-hydroxyhepta-24-diene-17-dioate isomerase [Mycobacterium sp. JDM601] Length=316 Score = 466 bits (1200), Expect = 4e-129, Method: Compositional matrix adjust. Identities = 228/316 (73%), Positives = 259/316 (82%), Gaps = 2/316 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 M+WVTYRS+ GER+GVL G+ I+A P +LL+L+ G DGLR AGERA+++P++ LD Sbjct 1 MRWVTYRSEDGERSGVLHGEVIHAAAPGTTLLELIRLGPDGLREAGERALQAPSSTPRLD 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +VTL APIPRPPSIRDSLCFLDHMRNC+ A G R L D WY+IPAFYFACP+TVLGPYD Sbjct 61 QVTLMAPIPRPPSIRDSLCFLDHMRNCRAATGRSRELEDAWYQIPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 DAPTAPGS QDFELE+AAVIGT G DL+V +AE++IIGYTIFNDWSARDLQ EG L I Sbjct 121 DAPTAPGSVCQDFELEVAAVIGTPGADLSVAEAEQAIIGYTIFNDWSARDLQAAEGVLAI 180 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 GQ KGKDSG+TLGPYLVTPDELEPY R GKLSL A++N +IG GST MDWSFGE+I Sbjct 181 GQGKGKDSGVTLGPYLVTPDELEPYRRNGKLSLHATAIINDVIIGIGSTEAMDWSFGEII 240 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRP--PESFPGWLHDGDVVTLQVEGLGETRQT 298 +YASRGV LTPGDVFGSGTVPTCTL+EHL P P+ FPGWL DGDVVTLQV+GLGE RQT Sbjct 241 SYASRGVPLTPGDVFGSGTVPTCTLLEHLDPALPQPFPGWLRDGDVVTLQVQGLGEVRQT 300 Query 299 VRTSGTPFPLALRPNP 314 VR S P PL R P Sbjct 301 VRASAPPLPLPERRRP 316 >gi|325003078|ref|ZP_08124190.1| hypothetical protein PseP1_30125 [Pseudonocardia sp. P1] Length=312 Score = 306 bits (783), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 168/310 (55%), Positives = 204/310 (66%), Gaps = 4/310 (1%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY + GERTG+L G+ + + P +L L+ GA L AG+ A R+P VV D Sbjct 1 MKWVTYEARAGERTGILDGETVRGLAPGTTLAGLLAAGA--LVEAGDDARRAPTEVVGTD 58 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V L AP+PRP SIRD LCFLDH+R C A+G L W P FYFA ++GPYD Sbjct 59 DVRLLAPLPRPVSIRDGLCFLDHLRGCYRALGRDESLHPAWSENPGFYFANADAIVGPYD 118 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 D P +PGS D ELEIAAVIGT G+DL ++AE I+GYT +NDW+ARD Q+ + I Sbjct 119 DVPVSPGSTMFDLELEIAAVIGTGGRDLDPQRAEEHIVGYTFYNDWTARDHQLRDMAQGI 178 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 G K KDS ITLGP LVT DELEPY R G+L+ V A V + GS A MDWSFGE++ Sbjct 179 GMGKSKDSAITLGPALVTVDELEPYRRDGRLAFEVSATVGDRELARGSLALMDWSFGELL 238 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPE--SFPGWLHDGDVVTLQVEGLGETRQT 298 AY SRG L PG V GSGTVP L+EH+ P+ +F GWL GDVV+L+ EGLGETRQT Sbjct 239 AYVSRGTDLAPGAVVGSGTVPGGCLLEHVDTPDLAAFTGWLQPGDVVSLRGEGLGETRQT 298 Query 299 VRTSGTPFPL 308 VR + PL Sbjct 299 VRPAPPVIPL 308 >gi|336461303|gb|EGO40175.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase [Mycobacterium avium subsp. paratuberculosis S397] Length=172 Score = 285 bits (729), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 137/172 (80%), Positives = 147/172 (86%), Gaps = 0/172 (0%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MKWVTY+ D GER GVL D IYAM V+LLDL+ RGA+GLR AGE A RSPAA V Sbjct 1 MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAA 60 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 L APIPRPPSIRDSLCFLDHMRNCQ A+G GRVL DTWYR+PAFYFACP+TVLGPYD Sbjct 61 RARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYD 120 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQ 172 DAPTAPGSAWQDFELEIAAVIGT GKDL+VEQAE++IIGYTIFNDWSARDLQ Sbjct 121 DAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGYTIFNDWSARDLQ 172 >gi|325003079|ref|ZP_08124191.1| beta-lactamase domain protein [Pseudonocardia sp. P1] Length=325 Score = 272 bits (696), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 142/304 (47%), Positives = 197/304 (65%), Gaps = 4/304 (1%) Query 323 VNPAPTRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREM 382 ++ P + + RGLH++ +AW LPDG +G+SN+GL+ G G SL+VDTLFDLALT EM Sbjct 1 MSTTPDLLQYRRGLHDLGSGCFAWLLPDGSWGWSNSGLITGSGTSLMVDTLFDLALTGEM 60 Query 383 LAAMKPVTERAPITDALITHSNGDHTHGTQLL-DRSVRIIAAKGTSEEIEHGPAPEMLAR 441 L ++PVT+R P+ + THS+GDH G QLL +R V IIA++ T+E I + LA Sbjct 61 LEGIRPVTDRHPLQTLVNTHSDGDHVFGNQLLAERDVEIIASEATAELITQDQV-DALAS 119 Query 442 IQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTA 501 ++ GP+ + R FG F F GI D TF ++++GGR V L+ +GPAHT Sbjct 120 VRRRS-GPIG-EFTRHAFGPFVFDGIVATGPDRTFTGQESLDVGGREVRLIQVGPAHTPG 177 Query 502 DSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPD 561 D++VHV DA +L+AGD+LFIG TP+VWAGP + W+AACD ++ +D T+VPGHGP T Sbjct 178 DTLVHVPDARLLYAGDILFIGGTPVVWAGPTSRWIAACDLILDMDVVTIVPGHGPATDKS 237 Query 562 GIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDP 621 G+ VR YL + ++A Y GL + EAV +IDLG +A + R+ NV Y+ELDP Sbjct 238 GVGPVRDYLQFVLDEATKRYEDGLGVEEAVASIDLGRFAGLPEHGRLAQNVLNVYQELDP 297 Query 622 DTPR 625 PR Sbjct 298 AVPR 301 >gi|254389627|ref|ZP_05004853.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 27064] gi|326445765|ref|ZP_08220499.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway)-like protein [Streptomyces clavuligerus ATCC 27064] gi|197703340|gb|EDY49152.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 27064] Length=326 Score = 265 bits (678), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/322 (47%), Positives = 195/322 (61%), Gaps = 19/322 (5%) Query 1 MKWVTYRSDH-GERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVAL 59 M+W+TY G RTG+LSGD ++ +P +LLDL+G + L A E+A+ PA +V Sbjct 1 MRWMTYDCPRTGPRTGLLSGDELHLLPGTTTLLDLLGDDGERLSAAAEQALTDPADIVTP 60 Query 60 DEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPY 119 D P+ RPPSIR+S+ FLDH+RN R L + P FYF+ P+ V GPY Sbjct 61 DPARTGPPL-RPPSIRESVGFLDHVRNTSPT----RALDPRFTEFPPFYFSNPAAVTGPY 115 Query 120 DDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLR 179 D P PG+ D+ELE+ AVIG +D+ E A R I GY +F DWSARDLQ+ E L Sbjct 116 TDIPLFPGTERFDYELEVGAVIGLPARDVKPEHAHRHIAGYILFCDWSARDLQLHEMGLG 175 Query 180 IGQAKGKDSGITLGPYLVTPDELEPY----CRGGKLS--------LRVIALVNGTVIGSG 227 +G AKGKD TLGPYLVTPD LE + G S L ++A VNG + SG Sbjct 176 LGPAKGKDGANTLGPYLVTPDVLEHHRATSSHGSHGSPDTYDTYDLEMVAEVNGVLTSSG 235 Query 228 STAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPT-CTLVEHLRPPESFPGWLHDGDVVT 286 + MDW+F ++IAY SRG TL PG++ GSGTVP+ C L ++ P +F GWL GDVV Sbjct 236 RLSAMDWTFADMIAYMSRGTTLLPGELIGSGTVPSGCLLEAFVQRPAAFRGWLQPGDVVR 295 Query 287 LQVEGLGETRQTVRTSGTPFPL 308 L+V+ LG TRQT+ S P PL Sbjct 296 LEVQELGHTRQTILPSPAPHPL 317 >gi|294816896|ref|ZP_06775538.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase [Streptomyces clavuligerus ATCC 27064] gi|294321711|gb|EFG03846.1| 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase [Streptomyces clavuligerus ATCC 27064] Length=323 Score = 259 bits (663), Expect = 8e-67, Method: Compositional matrix adjust. Identities = 147/311 (48%), Positives = 189/311 (61%), Gaps = 18/311 (5%) Query 11 GERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALDEVTLAAPIPR 70 G RTG+LSGD ++ +P +LLDL+G + L A E+A+ PA +V D P+ R Sbjct 9 GPRTGLLSGDELHLLPGTTTLLDLLGDDGERLSAAAEQALTDPADIVTPDPARTGPPL-R 67 Query 71 PPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYDDAPTAPGSAW 130 PPSIR+S+ FLDH+RN R L + P FYF+ P+ V GPY D P PG+ Sbjct 68 PPSIRESVGFLDHVRNTSPT----RALDPRFTEFPPFYFSNPAAVTGPYTDIPLFPGTER 123 Query 131 QDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGI 190 D+ELE+ AVIG +D+ E A R I GY +F DWSARDLQ+ E L +G AKGKD Sbjct 124 FDYELEVGAVIGLPARDVKPEHAHRHIAGYILFCDWSARDLQLHEMGLGLGPAKGKDGAN 183 Query 191 TLGPYLVTPDELEPY----CRGGKLS--------LRVIALVNGTVIGSGSTAQMDWSFGE 238 TLGPYLVTPD LE + G S L ++A VNG + SG + MDW+F + Sbjct 184 TLGPYLVTPDVLEHHRATSSHGSHGSPDTYDTYDLEMVAEVNGVLTSSGRLSAMDWTFAD 243 Query 239 VIAYASRGVTLTPGDVFGSGTVPT-CTLVEHLRPPESFPGWLHDGDVVTLQVEGLGETRQ 297 +IAY SRG TL PG++ GSGTVP+ C L ++ P +F GWL GDVV L+V+ LG TRQ Sbjct 244 MIAYMSRGTTLLPGELIGSGTVPSGCLLEAFVQRPAAFRGWLQPGDVVRLEVQELGHTRQ 303 Query 298 TVRTSGTPFPL 308 T+ S P PL Sbjct 304 TILPSPAPHPL 314 >gi|312194315|ref|YP_004014376.1| fumarylacetoacetate (FAA) hydrolase [Frankia sp. EuI1c] gi|311225651|gb|ADP78506.1| fumarylacetoacetate (FAA) hydrolase [Frankia sp. EuI1c] Length=313 Score = 259 bits (662), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 146/320 (46%), Positives = 193/320 (61%), Gaps = 18/320 (5%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 M++VTY D G+R GV++ ++A+P V+LLDL+ R DGLR AGERA+ SP+AV Sbjct 1 MRFVTYVDDDGDRVGVVADGQVHALPSGVTLLDLL-RAEDGLREAGERALASPSAVRPYS 59 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V L AP+P PP++RD + F H+ + GG + + WY PAFYF P V GP+D Sbjct 60 DVRLRAPLPTPPTVRDFMTFERHLEGV--LLLGGATVPERWYEAPAFYFTNPYAVRGPHD 117 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 D P PG D ELE+AAV+G +G+D++ E + I GYTI NDWSARDLQ E ++R+ Sbjct 118 DVPVPPGCQLFDLELEVAAVVGRTGRDVSPEAGDSYIAGYTIMNDWSARDLQFAEMEVRL 177 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 G KGKD+ TLGP LVTPDEL+ + G L + +NG +IG + M ++FG+++ Sbjct 178 GPTKGKDTATTLGPMLVTPDELQDWAAGTSYDLAMTVEINGELIGEDRLSSMAFTFGDLV 237 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVE-------HLRPPESFPGWLHDGDVVTLQVEGLG 293 AYASRG + PGDV GSGT L E PP L GD+VT+ VE LG Sbjct 238 AYASRGTEVRPGDVLGSGTCGGGCLAELWGRNGFDAHPP------LRPGDLVTVSVEQLG 291 Query 294 --ETRQTVRTSGTPFPLALR 311 TR T T P P A R Sbjct 292 ALTTRITAGTDPVPIPAARR 311 >gi|302530409|ref|ZP_07282751.1| predicted protein [Streptomyces sp. AA4] gi|302439304|gb|EFL11120.1| predicted protein [Streptomyces sp. AA4] Length=313 Score = 256 bits (655), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 143/309 (47%), Positives = 193/309 (63%), Gaps = 6/309 (1%) Query 330 VPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPV 389 +P+T+G H + + AW +PDG +G+SNAGL+AG G SLLVDTLFD+ +TREML ++ Sbjct 5 IPYTKGHHRLTEHCSAWLVPDGTWGWSNAGLIAGAGESLLVDTLFDVPMTREMLNGLQDA 64 Query 390 TERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIE-HGPAPEMLARIQTADLG 448 T +PI + TH+NGDH G +L+ IIA++ T+EE+ +GP L R G Sbjct 65 TVDSPIKTVVNTHANGDHWFGNELV-ADASIIASEATAEEMRTNGPD---LMRGLIRQEG 120 Query 449 PVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVA 508 P+ R+ + FDF I A+ TF L +++GG V++ LGPAHT DSVV V Sbjct 121 PLG-RFAQHILHPFDFDSITATPANRTFAGQLKLDIGGVAVEIRCLGPAHTEGDSVVLVP 179 Query 509 DAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRG 568 D GVL+AGDLLFIG TPI WAGP++NW+AACD M+ +DA VVPGHGPVT DGIR+V Sbjct 180 DEGVLYAGDLLFIGGTPITWAGPVSNWIAACDEMLKMDAEFVVPGHGPVTDADGIRSVLD 239 Query 569 YLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDL 628 YL + +A +R+G+ EA+ I LG +A + R+ NV Y ELDP+ R D Sbjct 240 YLQWVQAEAADRHRRGMPAEEAMRDISLGRFADLDEHGRLAQNVLAVYYELDPEMERVDT 299 Query 629 LALLVMQAE 637 + AE Sbjct 300 REVFRRIAE 308 >gi|154252104|ref|YP_001412928.1| beta-lactamase domain-containing protein [Parvibaculum lavamentivorans DS-1] gi|154156054|gb|ABS63271.1| beta-lactamase domain protein [Parvibaculum lavamentivorans DS-1] Length=326 Score = 253 bits (645), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 132/322 (41%), Positives = 195/322 (61%), Gaps = 13/322 (4%) Query 328 TRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMK 387 +R +T+GLH++ + +AW PDGG+G+SNAGL+ G S L+DTLFD+ LTR+ML AM+ Sbjct 6 SRFQYTKGLHDLGNGGYAWLQPDGGWGWSNAGLIVDGGESFLIDTLFDVPLTRDMLDAMR 65 Query 388 PVTERA--PITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARI--- 442 +A I + TH NGDH +G + + IIA K E + H P P +LA Sbjct 66 KAEPKAAAKINTLVNTHHNGDHCNGNECC-QGAEIIAHKLAVEGMRHEP-PALLAGFLDM 123 Query 443 --QTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTT 500 DLG +Y++ FG FDF G+ ++TF+ +L +G + + ++++GPAHT Sbjct 124 APGLGDLG----KYVKQCFGPFDFKGVTQTLPEVTFETELTRHVGSKEIRIMHVGPAHTP 179 Query 501 ADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGP 560 D++V+V +F GD+LFI PI+W GP++NW+ ACD ++A+D TVVPGHGP+TG Sbjct 180 GDALVYVPADKTVFTGDILFIEGHPIMWEGPVSNWIDACDRIMAMDVETVVPGHGPITGK 239 Query 561 DGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELD 620 +G++AVR YL ++ ++A Y GLS +A ID+ +Y SW D ER+VVNV Y+E Sbjct 240 NGVKAVRDYLVYVRDEARKRYDAGLSAFDAALDIDMTDYDSWGDGERIVVNVTTLYKEFS 299 Query 621 PDTPRQDLLALLVMQAEWAARH 642 D D+ + AE R Sbjct 300 GDDTPNDVPTIFGQMAEITKRQ 321 >gi|114798378|ref|YP_762133.1| metallo-beta-lactamase family protein [Hyphomonas neptunium ATCC 15444] gi|114738552|gb|ABI76677.1| metallo-beta-lactamase family protein [Hyphomonas neptunium ATCC 15444] Length=320 Score = 251 bits (642), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 142/312 (46%), Positives = 192/312 (62%), Gaps = 10/312 (3%) Query 328 TRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMK 387 R +T+GL ++ + ++AW PDGG+G+SNAGL+ ASLLVDTLFD+ALTREML AM Sbjct 3 ARWEYTKGLKDIGNGLYAWLQPDGGWGWSNAGLIRDGEASLLVDTLFDMALTREMLGAMA 62 Query 388 PVTE--RAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQT- 444 T I + TH+NGDH HG ++ IIA++ ++ E+ P P MLA+ + Sbjct 63 DATGIGAGKIGAIVNTHANGDHCHGNGCCPQA-EIIASEASAREMAEVP-PAMLAQFKKM 120 Query 445 -ADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADS 503 A LGP A Y D F FDF + R TF L +++G + V L+ +GPAHT D Sbjct 121 GAQLGP-AGSYFADIFAPFDFENVDERAPTQTFSGTLDLKVGDKAVRLIEVGPAHTGGDV 179 Query 504 VVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGI 563 +VHV +F GD+LFI TP++WAGP+ANW+ AC+ +IA+D +VPGHGPVT G+ Sbjct 180 LVHVPGDKAIFTGDILFIDGTPLMWAGPVANWIRACEQIIAMDVDVIVPGHGPVTDKAGV 239 Query 564 RAVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPD- 622 R V YLA + +A + GL + EA I LG+YASW D+ER+ VNV YRE D Sbjct 240 RRVADYLAFVDGEARKRFDAGLGVREAALDIALGDYASWGDAERIAVNVDSLYREYRGDG 299 Query 623 --TPRQDLLALL 632 TP +L AL+ Sbjct 300 KVTPVIELFALM 311 >gi|262197714|ref|YP_003268923.1| beta-lactamase [Haliangium ochraceum DSM 14365] gi|262081061|gb|ACY17030.1| beta-lactamase domain protein [Haliangium ochraceum DSM 14365] Length=314 Score = 249 bits (637), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 139/301 (47%), Positives = 191/301 (64%), Gaps = 13/301 (4%) Query 336 LHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPI 395 L EV D A+ DGG+G+SNAGL+ GDG SLLVDTLFDLALT+ ML + T API Sbjct 8 LCEVGDGCLAYLQGDGGWGWSNAGLIVGDGTSLLVDTLFDLALTQRMLDTLSAHTRAAPI 67 Query 396 TDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTA--DLGPVATR 453 + TH+NGDH G QL+D I+A+ T+ E+ P P +LA++ A ++G + Sbjct 68 ATVVNTHANGDHCFGNQLVD-GAEIVASAATAAEMPEVP-PALLAQLNAAPGEIGEL--- 122 Query 454 YLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVL 513 R FG F F GI+LR D TF+ L+I++GGR V+L+ +GPAHT D++ V DAGV+ Sbjct 123 -FRSFFGAFQFDGIELRLPDRTFEGRLSIDVGGRAVELIEVGPAHTRGDTLAVVPDAGVV 181 Query 514 FAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHI 573 + GD+LFIG PIVWAGP++NW+AACD ++ +DA +VPGHGP+T G+R VR YL ++ Sbjct 182 YTGDILFIGGAPIVWAGPLSNWIAACDLILGMDARAIVPGHGPITDNAGVREVREYLVYV 241 Query 574 AEQAEAAYRKGLSLPEAVETI--DLG---EYASWLDSERVVVNVYQRYRELDPDTPRQDL 628 +A A R G+ +A I LG ++ S + R+ VNV YR LDP D+ Sbjct 242 EREASARQRSGMDAFDAARDIAAQLGAREDFGSLGEFGRIAVNVEAVYRALDPSHKSPDV 301 Query 629 L 629 + Sbjct 302 V 302 >gi|289208218|ref|YP_003460284.1| beta-lactamase [Thioalkalivibrio sp. K90mix] gi|288943849|gb|ADC71548.1| beta-lactamase domain protein [Thioalkalivibrio sp. K90mix] Length=333 Score = 248 bits (634), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 136/309 (45%), Positives = 196/309 (64%), Gaps = 7/309 (2%) Query 332 FTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTE 391 + +GLH++ + WA+ PDGG+G+SNAGL+ +LLVDTLFD LT EMLA M T Sbjct 18 YRKGLHDLGNGTWAYLQPDGGWGWSNAGLIRDGEEALLVDTLFDERLTAEMLAQMDAATG 77 Query 392 --RAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARI--QTADL 447 I + TH+NGDHT G +L+ ++ IIA++ +++E+ P P MLA + Q+ + Sbjct 78 IGAGDINLLVNTHANGDHTFGNRLVHQA-EIIASQASADEMPELP-PAMLAGLMAQSGAM 135 Query 448 GPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHV 507 G V +YL+ FG FDF G++L TF +L +++G + V L+ +GPAHT D +VHV Sbjct 136 GEVG-KYLQRSFGAFDFGGVELTLPTRTFSGELGLKVGDKDVKLIEVGPAHTRGDVLVHV 194 Query 508 ADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVR 567 V++ GD+LFI TP++WAGP+ NW+AA D ++ +D T+VPGHGP+T G R VR Sbjct 195 PSDRVVYTGDILFIEGTPVMWAGPVGNWIAAIDRILGMDVETIVPGHGPITDHAGARQVR 254 Query 568 GYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQD 627 YL +I +A A + G+ EA I LG+YA+W D+ER+ VNV YRE DT D Sbjct 255 DYLVYIDREARARFDAGMPAAEASFDIALGDYANWGDAERIAVNVDTLYREYAGDTTTPD 314 Query 628 LLALLVMQA 636 ++ LL + A Sbjct 315 IMQLLRLMA 323 >gi|284042591|ref|YP_003392931.1| beta-lactamase [Conexibacter woesei DSM 14684] gi|283946812|gb|ADB49556.1| beta-lactamase domain protein [Conexibacter woesei DSM 14684] Length=315 Score = 244 bits (624), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 136/304 (45%), Positives = 185/304 (61%), Gaps = 5/304 (1%) Query 332 FTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTE 391 + +GLH+V +A+ P+G +G+SNAGL+A A+LLVDTLFDL LTREML AM+ Sbjct 6 YAKGLHDVGASTYAYLQPNGSWGWSNAGLIADGDATLLVDTLFDLRLTREMLDAMRRAVP 65 Query 392 RAPITDALI-THSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARI--QTADLG 448 A D L+ TH + DHT G QL+ + +I+A +EE+ G P L + Q +G Sbjct 66 AAAAIDVLVNTHGDPDHTFGNQLVGDA-QIVATARAAEEMLAGATPAALQELLAQAPRMG 124 Query 449 PVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVA 508 VA Y+ D FG FDFS ++L TF +LA+ +G V L+ LGPAHT D+VVHV Sbjct 125 -VAGDYVSDAFGAFDFSDVRLVPPSRTFGGELALTVGDLEVQLIELGPAHTGGDAVVHVP 183 Query 509 DAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRG 568 V+FAGD+LF G P+ W G + W+AAC+ ++ALD +VPGHGP+ G D +RA+R Sbjct 184 AQRVVFAGDVLFAGVHPVTWDGSVGGWIAACERLLALDVDAIVPGHGPIAGKDDVRALRD 243 Query 569 YLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDL 628 YLAH+ +A A +R L E I+L YA W + ERVV V YRE + R D Sbjct 244 YLAHVQAEAVAGWRAQLPAHEVARRIELAPYAGWCNPERVVTTVDAVYRERAGEGERADQ 303 Query 629 LALL 632 +AL+ Sbjct 304 IALI 307 >gi|331698695|ref|YP_004334934.1| fumarylacetoacetate (FAA) hydrolase [Pseudonocardia dioxanivorans CB1190] gi|326953384|gb|AEA27081.1| fumarylacetoacetate (FAA) hydrolase [Pseudonocardia dioxanivorans CB1190] Length=312 Score = 239 bits (611), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 149/315 (48%), Positives = 179/315 (57%), Gaps = 10/315 (3%) Query 2 KWVTYRSDHGE--RTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVAL 59 +WVTY S G R GVL ++ +LLDLVG L G + +PA V+ Sbjct 3 RWVTYSSGPGAPLRAGVLHEGRVHGRAGTETLLDLVG---TDLTAEGRDVLAAPAEVLDE 59 Query 60 DEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPY 119 V L APIP PPSIRD + F +H EA+G L WY PAFYF P V+G Sbjct 60 AAVVLHAPIPVPPSIRDFMAFENHAVTSLEAVGSS--LAPAWYDAPAFYFTNPRAVVGTG 117 Query 120 DDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLR 179 PGSA D+ELE+A VIG G D+ VEQA + G TI DWSARDLQ E + Sbjct 118 TPVAVPPGSAAFDYELEVAVVIGREGSDIPVEQAWSHVAGVTILCDWSARDLQAHEMAVG 177 Query 180 IGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEV 239 +G AKGKDS TLGP+LVTPDELEPY RG + A VNG +G+ A + WSF E+ Sbjct 178 LGPAKGKDSATTLGPWLVTPDELEPYRRGHGFDRAMRASVNGVGYSAGTLADLYWSFEEM 237 Query 240 IAYASRGVTLTPGDVFGSGTVPTCTLVE--HLRPPESFPGWLHDGDVVTLQVEGLGETRQ 297 IAYASRG L PGDV GSGTV T ++E + + +P WL GD V L VEGLG + Sbjct 238 IAYASRGTRLVPGDVLGSGTVGTGCILELSRVHGGDRYP-WLVPGDEVELSVEGLGSIQH 296 Query 298 TVRTSGTPFPLALRP 312 VR + PL RP Sbjct 297 VVRAGASVPPLRQRP 311 >gi|162453541|ref|YP_001615908.1| beta-lactamase [Sorangium cellulosum 'So ce 56'] gi|161164123|emb|CAN95428.1| Beta-lactamase [Sorangium cellulosum 'So ce 56'] Length=320 Score = 238 bits (608), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 135/318 (43%), Positives = 188/318 (60%), Gaps = 5/318 (1%) Query 328 TRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREML-AAM 386 +R + RGL ++ + +A+ P G +G SNAGLV DG +LLVDTLFDL TREML A Sbjct 2 SRWRYERGLEDIGNGCFAYLQPAGTWGLSNAGLVTSDGEALLVDTLFDLKRTREMLDAMR 61 Query 387 KPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTAD 446 A I + TH+NGDH +G L++ + IIA + + E++ PAP + ++ A Sbjct 62 AAAPAAARIGTVVNTHANGDHCYGNALVEGAT-IIATRAGAAEMDEVPAPMLAMLMRQAR 120 Query 447 LGPVAT--RYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSV 504 G YL FG FDF GI FD +L + +GG+ V L+ +GP+HT D + Sbjct 121 SGAAGALGEYLVHCFGAFDFDGIAPTPPTRVFDGELTVAVGGKEVRLIEVGPSHTKGDLL 180 Query 505 VHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIR 564 VHV V++ GD+LF+ TPI+WAGP+ NW+ ACD ++A DA +VPGHGP+T G+R Sbjct 181 VHVPADRVIYTGDVLFVDATPIMWAGPVGNWLKACDILLAADADVIVPGHGPITDRAGVR 240 Query 565 AVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELD-PDT 623 AVR YL +I ++A Y G+ +A I L +YASW D+ER+VVNV+ YRE Sbjct 241 AVRDYLVYIRDEARRRYDAGMPPADAARDIALADYASWSDAERIVVNVHTLYREFSGGKL 300 Query 624 PRQDLLALLVMQAEWAAR 641 P + L + AE A R Sbjct 301 PSPGPIELFGLMAELARR 318 >gi|297196822|ref|ZP_06914219.1| beta-lactamase [Streptomyces sviceus ATCC 29083] gi|197711590|gb|EDY55624.1| beta-lactamase [Streptomyces sviceus ATCC 29083] Length=382 Score = 238 bits (608), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 130/284 (46%), Positives = 179/284 (64%), Gaps = 6/284 (2%) Query 355 FSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLL 414 SNAGL+ G G SLLVDTL+DL LT+ ML A+ P+T API + TH NGDH G QL+ Sbjct 1 MSNAGLITGGGESLLVDTLYDLRLTKNMLDALTPLTATAPIATVVNTHGNGDHWFGNQLV 60 Query 415 DRSVRIIAAKGTSEEIEH-GPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNAD 473 + IIAA+G+ ++ GPA EMLA + A + R FG FD++GI+ + Sbjct 61 AHA-EIIAARGSVADMRQVGPA-EMLA---LTGMDSPAGHFARRIFGRFDYTGIEPALPN 115 Query 474 LTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIA 533 FD + +++GG V L+++GPAH+ +D++VHV A ++ GD++F G PIVW GP A Sbjct 116 RIFDGETVLDIGGTEVRLIDVGPAHSASDTIVHVPQARTVYTGDIVFAGAAPIVWHGPFA 175 Query 534 NWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAAYRKGLSLPEAVET 593 +W+AACD ++ LDA TVVPGHGPVT +R +R YL ++ EQA A + G+ + +A Sbjct 176 HWLAACDLLLGLDADTVVPGHGPVTTKQAVREIRDYLEYVHEQATARFTAGMPVMDAACD 235 Query 594 IDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAE 637 I LG +A +SER+ VNV+ YRELDP P D L AE Sbjct 236 IRLGRFADLHESERLAVNVHTVYRELDPSLPPLDGPGLFGCMAE 279 >gi|254389628|ref|ZP_05004854.1| beta-lactamase [Streptomyces clavuligerus ATCC 27064] gi|197703341|gb|EDY49153.1| beta-lactamase [Streptomyces clavuligerus ATCC 27064] Length=509 Score = 238 bits (607), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 132/305 (44%), Positives = 173/305 (57%), Gaps = 4/305 (1%) Query 336 LHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPI 395 LH + AW G+G+SNAGL+ G +SLLVDTLFDL LT MLAAM P P+ Sbjct 191 LHRLTGPCSAWIADHAGWGYSNAGLIVGGSSSLLVDTLFDLRLTGAMLAAMAPAVRDGPL 250 Query 396 TDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYL 455 + TH+NGDH G QL+ IIA+ + + + A ++ GP +L Sbjct 251 RTVVNTHANGDHYFGNQLVP-DAEIIASGSAAAHMVQDDVESLRADLRAP--GPHGD-HL 306 Query 456 RDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFA 515 R FG FDF GI + TFD +L ++LGG V L GPAHT D +VHV A ++ Sbjct 307 RHVFGGFDFDGITVTPPTRTFDGELTLDLGGVEVRCLTAGPAHTEGDVIVHVPAARTVYV 366 Query 516 GDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAE 575 GDLLF G TP+ WAGP++ W+AACD ++AL A TVVPGHGPVTGP +R R YL + E Sbjct 367 GDLLFSGGTPVAWAGPLSGWIAACDRILALGADTVVPGHGPVTGPHALRETRAYLTLVEE 426 Query 576 QAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQ 635 A A + G S E V + LG + +W + R+V NV YR LDP P L++ Sbjct 427 AATAGFHAGRSQQETVAALRLGRFGAWSEPGRLVQNVAAVYRHLDPTLPHLPHAELMMRM 486 Query 636 AEWAA 640 ++ A Sbjct 487 GDYEA 491 >gi|294816897|ref|ZP_06775539.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] gi|326445764|ref|ZP_08220498.1| beta-lactamase domain protein [Streptomyces clavuligerus ATCC 27064] gi|294321712|gb|EFG03847.1| bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] Length=327 Score = 236 bits (602), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 132/305 (44%), Positives = 173/305 (57%), Gaps = 4/305 (1%) Query 336 LHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPI 395 LH + AW G+G+SNAGL+ G +SLLVDTLFDL LT MLAAM P P+ Sbjct 9 LHRLTGPCSAWIADHAGWGYSNAGLIVGGSSSLLVDTLFDLRLTGAMLAAMAPAVRDGPL 68 Query 396 TDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYL 455 + TH+NGDH G QL+ IIA+ + + + A ++ GP +L Sbjct 69 RTVVNTHANGDHYFGNQLVP-DAEIIASGSAAAHMVQDDVESLRADLRAP--GPHGD-HL 124 Query 456 RDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFA 515 R FG FDF GI + TFD +L ++LGG V L GPAHT D +VHV A ++ Sbjct 125 RHVFGGFDFDGITVTPPTRTFDGELTLDLGGVEVRCLTAGPAHTEGDVIVHVPAARTVYV 184 Query 516 GDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAE 575 GDLLF G TP+ WAGP++ W+AACD ++AL A TVVPGHGPVTGP +R R YL + E Sbjct 185 GDLLFSGGTPVAWAGPLSGWIAACDRILALGADTVVPGHGPVTGPHALRETRAYLTLVEE 244 Query 576 QAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQ 635 A A + G S E V + LG + +W + R+V NV YR LDP P L++ Sbjct 245 AATAGFHAGRSQQETVAALRLGRFGAWSEPGRLVQNVAAVYRHLDPTLPHLPHAELMMRM 304 Query 636 AEWAA 640 ++ A Sbjct 305 GDYEA 309 >gi|297204670|ref|ZP_06922067.1| hydroxylase [Streptomyces sviceus ATCC 29083] gi|197710737|gb|EDY54771.1| hydroxylase [Streptomyces sviceus ATCC 29083] Length=323 Score = 234 bits (598), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 141/315 (45%), Positives = 182/315 (58%), Gaps = 10/315 (3%) Query 1 MKWVTYRSDHGERTGVLSGDA-IYAMPPDVSLLDLVGRG--ADGLRTAGERAVRSPAAVV 57 M++ TY R V+ D + +P SL +L+G G D L G ++ P Sbjct 1 MRFATYEHRDQRRVAVVEEDGTLLPVPGARSLTELIGSGDGLDALLDVGTASLDVPPGP- 59 Query 58 ALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLG 117 + EV L P+ +PP++RD + F +H+ + ++ G + + WY P FYF P V+G Sbjct 60 HVSEVRLLPPL-QPPTVRDFVTFEEHVEGVRRSVDGAGGVPEAWYDAPTFYFTNPYAVIG 118 Query 118 PYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQ 177 +DD P PGS DFELE+AAVIG G+DLT EQA +IGYT+FNDWSARDLQ E Q Sbjct 119 AHDDVPVPPGSEVLDFELEVAAVIGREGRDLTPEQARDRVIGYTVFNDWSARDLQSREMQ 178 Query 178 LRIGQAKGKDSGITLGPYLVTPDELEPYCRG-GKLSLRVIALVNGTVIGSGSTAQMDWSF 236 +R+G KGKD+ TLGPYLVT DELEPY G L L + A VNG V+G + M W+F Sbjct 179 VRLGPCKGKDTAATLGPYLVTADELEPYRDSDGFLRLALTAQVNGEVVGKDLLSNMSWTF 238 Query 237 GEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHL---RPPESFPGWLHDGDVVTLQVEGLG 293 E++AYASRG + PGDV GSGT + L R +S P L GD VTL VEG+G Sbjct 239 EEMVAYASRGTVVRPGDVLGSGTCGNGGCLAELWGVRGAQS-PPPLKPGDTVTLTVEGIG 297 Query 294 ETRQTVRTSGTPFPL 308 TV P PL Sbjct 298 TVSNTVVPGKDPVPL 312 >gi|88811790|ref|ZP_01127044.1| hypothetical protein NB231_05275 [Nitrococcus mobilis Nb-231] gi|88791181|gb|EAR22294.1| hypothetical protein NB231_05275 [Nitrococcus mobilis Nb-231] Length=319 Score = 233 bits (593), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 128/310 (42%), Positives = 182/310 (59%), Gaps = 7/310 (2%) Query 332 FTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVT- 390 F +GLHE + ++++ PDG +G+SNAGLV SLLVDTLFD LTREML+ M+ T Sbjct 6 FQKGLHETGNGIYSYLQPDGSWGWSNAGLVVDGDQSLLVDTLFDAPLTREMLSTMRDATG 65 Query 391 -ERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTA--DL 447 I + TH+NGDHTHG L + IIA++ + E+E PE L +I A L Sbjct 66 IPAEKIGTVVNTHANGDHTHGNGLCTHA-EIIASEAGAREMETF-GPERLQQIMQAAPHL 123 Query 448 GPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHV 507 G Y + F FDFS + + TF+ + + +G ++VDL+ +GPAHT D +V V Sbjct 124 GETG-EYFLEIFRPFDFSDVAEKLPTKTFNGAMTLTVGDKQVDLVEVGPAHTQGDVLVFV 182 Query 508 ADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVR 567 +F GD+LFI TPI+WAGP++NW+ ACD +I + +VPGHGP+T G++ V+ Sbjct 183 PGDSTVFTGDILFIDGTPIMWAGPVSNWLKACDLIIDREPEIIVPGHGPITDVTGVKRVQ 242 Query 568 GYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQD 627 YLA+I +A Y G+ EA I + ++ SW D+ER+ VNV YRE T + Sbjct 243 EYLAYIDAEARKRYDAGMEAKEAAFDISISDFESWTDAERIAVNVSTLYREYSGSTDAPN 302 Query 628 LLALLVMQAE 637 L + + AE Sbjct 303 TLEIFTLMAE 312 >gi|297196820|ref|ZP_06914217.1| hydroxylase [Streptomyces sviceus ATCC 29083] gi|197711592|gb|EDY55626.1| hydroxylase [Streptomyces sviceus ATCC 29083] Length=314 Score = 232 bits (592), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 140/316 (45%), Positives = 181/316 (58%), Gaps = 17/316 (5%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MK+ T+ D ++G+++ ++ V LLDL+ G LR AGERA+ + V L Sbjct 1 MKFATFVHDGKWQSGLVADGQVHPFEYPVELLDLIAEGEQSLRGAGERALTG-SLPVPLA 59 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V L P+ RPP++RD + F H+ A G G + D WY PAFYF P +V+G +D Sbjct 60 DVRLLPPL-RPPTVRDYMTFEAHVAGI--AQGYGDTVPDEWYEAPAFYFTNPYSVIGAHD 116 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 D P PG A DFELE+AAVIG G+DL +QA I+GYTI NDWSARDLQ E ++++ Sbjct 117 DVPVPPGCARFDFELEVAAVIGKPGRDLPPDQAREHILGYTILNDWSARDLQGREMKVKL 176 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCR-GGKLSLRVIALVNGTVIGSGSTAQMDWSFGEV 239 G AKGKD+ TLGP+LVT DELEP+ G L L + VNG +G A M W+F E+ Sbjct 177 GPAKGKDTATTLGPWLVTADELEPHRNPEGFLDLTLTVQVNGETVGQDRLANMAWTFEEM 236 Query 240 IAYASRGVTLTPGDVFGSGTVPTCTLVEH-------LRPPESFPGWLHDGDVVTLQVEGL 292 AYASRG + PGDV GSGT + L PP P GD VT+ VEG+ Sbjct 237 AAYASRGTWIRPGDVLGSGTCGNGGCLAELWGRNGLLEPPPLAP-----GDTVTMTVEGI 291 Query 293 GETRQTVRTSGTPFPL 308 G TV P L Sbjct 292 GAISNTVVEGVAPIRL 307 >gi|108805050|ref|YP_644987.1| fumarylacetoacetate (FAA) hydrolase [Rubrobacter xylanophilus DSM 9941] gi|108766293|gb|ABG05175.1| fumarylacetoacetate (FAA) hydrolase [Rubrobacter xylanophilus DSM 9941] Length=320 Score = 231 bits (588), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 134/309 (44%), Positives = 178/309 (58%), Gaps = 6/309 (1%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 M+ V Y + ER GV+SG+ I +P +LDL+ + +R R+ A V L Sbjct 1 MRIVRYETGGIERLGVVSGEEIGPLPEGTDVLDLLAADPE----ERDRIARTAEASVPLT 56 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 V L AP+ +PP++RD + F +H+ ++ + + WY IP FYF P +V+GP D Sbjct 57 GVRLLAPL-QPPTLRDFVVFEEHVEGITRSVSEEGGVPEAWYEIPTFYFGNPYSVIGPQD 115 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 PG DFELE+AA+IG +G +L E+A I GYTI NDWSARDLQ E Q+ + Sbjct 116 PVAVPPGCEALDFELEVAAIIGRAGSNLAPEEARGHIAGYTILNDWSARDLQRHEMQIGL 175 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 G AKGKD TLGP++VT DELEPY R G+L L + VNG +G + A M WSF E++ Sbjct 176 GPAKGKDFANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNGEKLGDDTLANMAWSFEELV 235 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHL-RPPESFPGWLHDGDVVTLQVEGLGETRQTV 299 AYASRG + PGDV GSGT + L E R P L GDVV + VEG+G V Sbjct 236 AYASRGTWVRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLEPGDVVRMTVEGIGTIENRV 295 Query 300 RTSGTPFPL 308 +P P+ Sbjct 296 VEGVSPVPI 304 >gi|148254097|ref|YP_001238682.1| putative fumarylacetoacetate (FAA) hydrolase [Bradyrhizobium sp. BTAi1] gi|146406270|gb|ABQ34776.1| putative Fumarylacetoacetate (FAA) hydrolase [Bradyrhizobium sp. BTAi1] Length=311 Score = 231 bits (588), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 128/313 (41%), Positives = 183/313 (59%), Gaps = 9/313 (2%) Query 1 MKWVTYRS--DHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVA 58 M+W TY S D+ +R G++ G+ I+ + P ++L++L+ G L+ A+ P+ ++ Sbjct 1 MRWSTYVSPSDNKDRVGLVVGETIHGLAPGLTLIELLRMGGAALQDYAAAAIDRPSELIE 60 Query 59 LDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGP 118 L +L AP+P PPSIRD + F H++ A+ R L WY++P FYF P + G Sbjct 61 LSRASLRAPVPTPPSIRDFMAFEAHVKTSMRALN--RELHPDWYQLPVFYFTNPVSARGA 118 Query 119 YDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQL 178 + +PGS D+ELE+AA+IG+ G D+ VE A I G+ + DWSARDLQ E Q+ Sbjct 119 REAVKISPGSQAFDYELEVAAIIGSPGSDIAVEDARSHIAGFCLMADWSARDLQAREMQM 178 Query 179 RIGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGE 238 +G +KGKD ++ GP++VTPDELE G + + A VN SG+ A + WSF E Sbjct 179 GLGPSKGKDGAMSFGPFMVTPDELEERIVGHSHDMALSAFVNDKPYSSGNLADIYWSFAE 238 Query 239 VIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRP---PESFPGWLHDGDVVTLQVEGLGET 295 +I+YASRG L GDV GSGTV T +VE LR PE++P WL +GD V L + LG Sbjct 239 MISYASRGTRLVTGDVIGSGTVGTGCIVE-LRTTSGPEAYP-WLSEGDRVRLSADILGSI 296 Query 296 RQTVRTSGTPFPL 308 + P PL Sbjct 297 DVRIERGTEPLPL 309 >gi|84687095|ref|ZP_01014977.1| hypothetical protein 1099457000268_RB2654_23338 [Maritimibacter alkaliphilus HTCC2654] gi|84664866|gb|EAQ11348.1| hypothetical protein RB2654_23338 [Rhodobacterales bacterium HTCC2654] Length=333 Score = 227 bits (579), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 115/296 (39%), Positives = 179/296 (61%), Gaps = 6/296 (2%) Query 328 TRVPFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMK 387 ++ +T+GLH++ + W + +PDG +G+SNAG++A A+LLVDTLFDLA T++ML MK Sbjct 2 SKWKYTKGLHDLGNGCWGYLVPDGSWGWSNAGIIADGEANLLVDTLFDLACTKDMLDDMK 61 Query 388 PVTERAPITDALI-THSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQT-- 444 A L+ TH++GDHT G QL+ + RII +GT + + P+ML + Sbjct 62 ANVPGADNIGILVNTHADGDHTFGNQLV-KGARIIGTEGTVADFDRFD-PKMLDEVNRNP 119 Query 445 ADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSV 504 A G A ++ + F FDFSGI L TF + I +G +RV+L+ +GPAH+ D++ Sbjct 120 AKFGK-AGEFMAECFKPFDFSGITLTPPTETFKDKMTIMVGDKRVELIEVGPAHSLGDAL 178 Query 505 VHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIR 564 ++V + VL+ GD+LF TPI W GP+ W+ C+ ++ +D +V GHGP++ D +R Sbjct 179 IYVPEDKVLYTGDILFSAGTPIAWYGPVVRWINVCNMVLDMDVEVIVAGHGPISTKDDVR 238 Query 565 AVRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELD 620 +R YL + E A Y +G+ +A IDLG+Y W D+ERV+V + Y + + Sbjct 239 KMRDYLMDVTEMARPLYEQGVDFLDAAYKIDLGDYKDWTDAERVIVTIQTLYDDFE 294 >gi|290963330|ref|YP_003494512.1| hydroxylase [Streptomyces scabiei 87.22] gi|260652856|emb|CBG75991.1| putative hydroxylase [Streptomyces scabiei 87.22] Length=323 Score = 225 bits (574), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 136/314 (44%), Positives = 178/314 (57%), Gaps = 8/314 (2%) Query 1 MKWVTYRSDHGERTGVLSGDA-IYAMPPDVSLLDLVGRGAD--GLRTAGERAVRSPAAVV 57 M++ Y + V+ D ++ +P SL +L+ RG L G + PA Sbjct 1 MRFAAYEYRNRRHVAVVEEDGTLFPLPGVGSLTNLLARGGGLPALLEEGNATLDLPAGP- 59 Query 58 ALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLG 117 + EV L P+ +PP+IRD + F +H+ + ++ G + + WY P FYF P ++G Sbjct 60 HVSEVRLLPPL-QPPTIRDFVTFEEHVEGVRRSVDGVGGVPEAWYDAPTFYFTNPYALIG 118 Query 118 PYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQ 177 +DD P PGS+ DFELE+AAVIG G++L+ QA IIGYT+FNDWSARDLQ E Q Sbjct 119 AHDDVPVPPGSSALDFELEVAAVIGREGRNLSPRQARDHIIGYTVFNDWSARDLQSREMQ 178 Query 178 LRIGQAKGKDSGITLGPYLVTPDELEPYCRG-GKLSLRVIALVNGTVIGSGSTAQMDWSF 236 +R+G KGKD+ TLGPYLVT DELEPY G L L + A VNG V+G + M W+F Sbjct 179 VRLGPCKGKDTAATLGPYLVTADELEPYRDADGFLRLGLTAAVNGEVVGKDLLSNMSWTF 238 Query 237 GEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHL--RPPESFPGWLHDGDVVTLQVEGLGE 294 E+ AYASRG + PGDV GSGT + L E P L GD VTL VEG+G Sbjct 239 EEMAAYASRGTVVRPGDVLGSGTCGNGGCLAELWGVRGEQSPPPLKPGDTVTLTVEGIGT 298 Query 295 TRQTVRTSGTPFPL 308 TV P PL Sbjct 299 VSNTVVAGSAPVPL 312 >gi|334140774|ref|YP_004533980.1| metallo-beta-lactamase family protein [Novosphingobium sp. PP1Y] gi|333938804|emb|CCA92162.1| metallo-beta-lactamase family protein [Novosphingobium sp. PP1Y] Length=336 Score = 224 bits (572), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 119/314 (38%), Positives = 187/314 (60%), Gaps = 5/314 (1%) Query 332 FTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTE 391 +T+G+H++ WAW PDGG+G+SNAGLV SLLVDTL+DL +T ML+ M+ T Sbjct 5 YTQGMHQIGQDCWAWIQPDGGWGWSNAGLVTDGECSLLVDTLYDLDMTANMLSVMRDTTP 64 Query 392 RAPITDALI-THSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPV 450 A + L+ +H++GDHT+G Q++ S RIIA+K T+ E P ++ +Q AD+ Sbjct 65 AANDINVLVNSHADGDHTYGNQIVGTS-RIIASKATAAEFFSLPPAKIETIVQQADVLGE 123 Query 451 ATRYLRD--RFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVA 508 +Y+ R F F+G +L T++R+L +++G + V L+N+GPAHT D++VH Sbjct 124 GAQYIAGWARDHGFTFAGNQLVGPTETYERELDLKVGDKEVRLINVGPAHTAGDTLVHSI 183 Query 509 DAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRG 568 V++ GD+LF+G P +WAG + W+AACD M+ +D VVPGHGP+T G+R Sbjct 184 QDKVVYTGDILFMGVHPAIWAGSLDGWLAACDRMLTMDVDVVVPGHGPITDKQGVRLFHT 243 Query 569 YLAHIAEQAEAAYRKGLSLPEAVETIDLG-EYASWLDSERVVVNVYQRYRELDPDTPRQD 627 YLA + +A + GLS+ +A + I L + WL ER+ +V + + T ++ Sbjct 244 YLASLRREARIRFEAGLSVEQAADDIRLEPPFDEWLLPERIAGSVNSLFLQWGSPTAEKE 303 Query 628 LLALLVMQAEWAAR 641 + + + A +A R Sbjct 304 FMKVFDLIARYAKR 317 >gi|254483370|ref|ZP_05096600.1| metallo-beta-lactamase domain protein [marine gamma proteobacterium HTCC2148] gi|214036354|gb|EEB77031.1| metallo-beta-lactamase domain protein [marine gamma proteobacterium HTCC2148] Length=318 Score = 224 bits (571), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 121/309 (40%), Positives = 170/309 (56%), Gaps = 2/309 (0%) Query 332 FTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTE 391 GL+ + + WAW +G+SNAGL+A SLLVDTL+DL LT EML M+ Sbjct 1 MAEGLNNLGNGAWAWLAHSNSWGWSNAGLIADGEESLLVDTLYDLRLTSEMLKRMRAAEP 60 Query 392 RAPITDALI-THSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPV 450 A D L+ TH+NGDH HG +L+ + I + +E E P AD+G V Sbjct 61 LANNIDTLVNTHANGDHCHGNELVSGAQIIASTASAAEMAELPPEAMAAIVEAAADMGAV 120 Query 451 ATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADA 510 +Y FG F F I + TF+ +LA+++G + V L+ +GPAHT D +V+ Sbjct 121 G-QYFLACFGQFRFDDICHTPPNRTFEGELALQVGDKPVQLIEVGPAHTRGDVLVYSPRD 179 Query 511 GVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYL 570 +F GD+LFI TP++W GP+ANW+ AC + A+D +VPGHGP+T G+ VR YL Sbjct 180 RTVFTGDILFIEGTPVMWQGPVANWIKACQLIEAMDVEHIVPGHGPLTDKAGVSKVRHYL 239 Query 571 AHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLA 630 ++ ++A Y G+ EA I+L EY+SW D ER+ VNV YRE + D+ Sbjct 240 EYVRDEARQRYDSGMGAFEAARDIELSEYSSWSDPERIAVNVDSLYREFSGEQTMTDIFE 299 Query 631 LLVMQAEWA 639 L A A Sbjct 300 LFARMASLA 308 >gi|21224621|ref|NP_630400.1| hydroxylase [Streptomyces coelicolor A3(2)] gi|13872767|emb|CAC37524.1| putative hydroxylase [Streptomyces coelicolor A3(2)] Length=323 Score = 224 bits (570), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 138/314 (44%), Positives = 176/314 (57%), Gaps = 8/314 (2%) Query 1 MKWVTYRSDHGERTGVLSGD-AIYAMPPDVSLLDLVGR--GADGLRTAGERAVRSPAAVV 57 M++ Y H +R V+ D ++ +P SL DL+ R G GL AG A+ P Sbjct 1 MRFAAYEHRHRQRVAVVEEDGSLRPLPGVTSLTDLLARADGLPGLLAAGRAALGVPPGP- 59 Query 58 ALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLG 117 + +V L P+ RP S+RD + F +H+ + ++ G + + WY P FYF P + G Sbjct 60 HVSQVRLLPPL-RPASVRDFVTFEEHVEGVRRSVDGVAGVPEQWYAAPTFYFTNPHAIHG 118 Query 118 PYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQ 177 DD P PGSA DFELE+ AVIG G+DLT EQA I+GYT+FNDWSARDLQ +E Sbjct 119 HRDDIPVPPGSAVLDFELEVGAVIGREGRDLTPEQARDHIVGYTVFNDWSARDLQGVEMT 178 Query 178 LRIGQAKGKDSGITLGPYLVTPDELEPYCRG-GKLSLRVIALVNGTVIGSGSTAQMDWSF 236 + +G KGKD TLGPYLVT DELEPY G L L + A VNG +G + M W+F Sbjct 179 VGLGPCKGKDGATTLGPYLVTADELEPYRDADGFLRLALTAEVNGERVGEDLLSNMSWTF 238 Query 237 GEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHL--RPPESFPGWLHDGDVVTLQVEGLGE 294 E+ AYASRG + PGDV GSGT + L R + P L GD V L V+GLG Sbjct 239 EEMTAYASRGTRVVPGDVLGSGTCGNGGCLAELWGRRGKQDPPPLRPGDTVALTVQGLGT 298 Query 295 TRQTVRTSGTPFPL 308 TV P PL Sbjct 299 LTNTVVPGPDPVPL 312 >gi|345137925|dbj|BAK67534.1| putative hydrolase [Sphingobium sp. SYK-6] Length=329 Score = 218 bits (556), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 124/319 (39%), Positives = 182/319 (58%), Gaps = 8/319 (2%) Query 331 PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKP-V 389 PFT+G+H++ + ++ + PDG +G+SNAGL+A G +LLVDTL + LTREML K V Sbjct 5 PFTQGIHDIGNGLYGYVQPDGTWGWSNAGLIASGGETLLVDTLMSVPLTREMLDQFKARV 64 Query 390 TERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGP 449 E A I + TH+N DH G L+ + I + E P R +G Sbjct 65 PEAAKIDRLVNTHANPDHFFGNGLVADAEIIGTVEAKKEMAGFNPRALAALRDNYQTMGD 124 Query 450 VATRYLRDRFG-HFDFSGIK-LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHV 507 A +L + G FDFSG+ + + TF++ L + +G ++V+L +LGPAHT +D++V V Sbjct 125 -AGAFLYETMGRKFDFSGVDDVTLPNRTFEKHLTLTVGDKQVELTDLGPAHTDSDTIVWV 183 Query 508 ADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVR 567 + V+F GDLLF PI+WAGP+ NW+AAC +I LD VVPGHGP+T + A++ Sbjct 184 PEDRVVFTGDLLFNEGHPIMWAGPVENWIAACQRIIDLDPQVVVPGHGPITERTAVAAMK 243 Query 568 GYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYR----ELDPDT 623 GY ++ ++A A + G+ EA I++ EY W D ER+V NV+ YR + P+ Sbjct 244 GYFEYVRDEARARFDAGMGFDEAARDINMQEYRGWSDPERIVANVFSLYRQWGAQFTPEQ 303 Query 624 PRQDLLALLVMQAEWAARH 642 R A+ E AA H Sbjct 304 QRDLFGAMGRYHKELAAHH 322 >gi|345012276|ref|YP_004814630.1| fumarylacetoacetate (FAA) hydrolase [Streptomyces violaceusniger Tu 4113] gi|344038625|gb|AEM84350.1| fumarylacetoacetate (FAA) hydrolase [Streptomyces violaceusniger Tu 4113] Length=327 Score = 218 bits (555), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 129/313 (42%), Positives = 171/313 (55%), Gaps = 7/313 (2%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 MK+V Y R GV+ GD + + LL L+ G L AG A+R A V L Sbjct 1 MKFVRYADGTSSRVGVVDGDLLRVVDGLADLLPLIEAGEAELLAAGRTALRR-GATVPLP 59 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 ++ +PI PP++RD F H+R + G + WY +P FYF+ P V+G Sbjct 60 DIVPLSPIATPPTVRDFYAFEQHVRAGRAWRG--LEMEPDWYELPVFYFSSPYAVMG-CG 116 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 P PG+ DFELE+AAV+G G+DLT + AE +I GY + NDWS RD+Q E +L + Sbjct 117 PVPMTPGAERFDFELEVAAVVGHGGRDLTAQDAEHAIAGYCVLNDWSGRDVQQREMKLSM 176 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVI 240 G KGKD+ +LGPY VTPDE+ + L + VNG + + WSFGE+I Sbjct 177 GPVKGKDTATSLGPYFVTPDEIADFRESNGYRLEMTCTVNGAPYSRALWSDIHWSFGEMI 236 Query 241 AYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPES--FPGWLHDGDVVTLQVEGLGETRQT 298 AYASRG + PGDV GSGT T ++E R +S +P WL GD V +EGLGE R T Sbjct 237 AYASRGAEVRPGDVIGSGTCGTGCILELSRTHDSATYP-WLQPGDEVVAAIEGLGELRNT 295 Query 299 VRTSGTPFPLALR 311 V + PL R Sbjct 296 VTGAAPVIPLRTR 308 >gi|289768061|ref|ZP_06527439.1| hydroxylase [Streptomyces lividans TK24] gi|289698260|gb|EFD65689.1| hydroxylase [Streptomyces lividans TK24] Length=323 Score = 218 bits (554), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 136/314 (44%), Positives = 174/314 (56%), Gaps = 8/314 (2%) Query 1 MKWVTYRSDHGERTGVLSGD-AIYAMPPDVSLLDLVGR--GADGLRTAGERAVRSPAAVV 57 M++ Y R V+ D +++ +P SL DL+ R G GL AG A+ P Sbjct 1 MRFAAYEHRQRHRVAVVEEDGSLHPLPGVTSLTDLLVRADGLPGLLAAGRAALGVPPGP- 59 Query 58 ALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLG 117 + +V L P+ RP S+RD + F +H+ + ++ G + + WY P FYF P + G Sbjct 60 HVSQVRLLPPL-RPASVRDFVTFEEHVEGVRRSVDGVAGVPEQWYAAPTFYFTNPHAIHG 118 Query 118 PYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQ 177 DD P PG+A DFELE+ AVIG G+DLT EQA I+GYT+FNDWSARDLQ E Sbjct 119 HRDDIPVPPGAAVLDFELEVGAVIGREGRDLTPEQARDHIVGYTVFNDWSARDLQGAEMT 178 Query 178 LRIGQAKGKDSGITLGPYLVTPDELEPYCR-GGKLSLRVIALVNGTVIGSGSTAQMDWSF 236 + +G KGKD TLGPYLVT DELEPY G L L + A VNG +G + M W+F Sbjct 179 VGLGPCKGKDGATTLGPYLVTADELEPYRDVDGFLRLALTAEVNGERVGEDLLSNMSWTF 238 Query 237 GEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHL--RPPESFPGWLHDGDVVTLQVEGLGE 294 E+ AYASRG + PGDV GSGT + L R + P L GD V L V+GLG Sbjct 239 EEMTAYASRGTRVVPGDVLGSGTCGNGGCLAELWGRRGKQDPPPLRPGDTVALTVQGLGT 298 Query 295 TRQTVRTSGTPFPL 308 TV P PL Sbjct 299 LTNTVVPGPDPVPL 312 >gi|334142644|ref|YP_004535852.1| beta-lactamase domain-containing protein [Novosphingobium sp. PP1Y] gi|333940676|emb|CCA94034.1| beta-lactamase domain-containing protein [Novosphingobium sp. PP1Y] Length=328 Score = 212 bits (540), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 113/307 (37%), Positives = 173/307 (57%), Gaps = 9/307 (2%) Query 331 PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVT 390 PFT+G+H++ + V+ + PDG +G+SNAGL+A G +LLVDTL +LTR+ML V Sbjct 5 PFTQGVHDIGNGVYGYVQPDGTWGWSNAGLIASRGETLLVDTLMSRSLTRDMLNDFARVP 64 Query 391 ERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARI-----QTA 445 I + TH+N DH G L++ IIA + T+ E+ P+ A + + Sbjct 65 GGDHIDRLVNTHANPDHFVGNGLVE-GAEIIATRETAREMADF-NPQQFASLPDNWEKMG 122 Query 446 DLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVV 505 D G + +F D + + TF+ L + +G ++VDL++LGPAHTT+D+++ Sbjct 123 DAGAFLYETMGRKFDWTDLDSVAMPTR--TFEHRLTLSVGDKQVDLVDLGPAHTTSDTIL 180 Query 506 HVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRA 565 + D V+F GDLLF PI+W GP+ NW+AACD +I LD VVPGHGP+T + + Sbjct 181 WIPDDRVVFTGDLLFNEGHPIMWEGPVENWIAACDHIITLDPQVVVPGHGPITDKSAVAS 240 Query 566 VRGYLAHIAEQAEAAYRKGLSLPEAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPR 625 ++ Y ++ E+ Y G+ E I++ EY W D ER+V NV+ YR+ + P Sbjct 241 LKAYFEYVREETRKRYEAGMGWKETARDINMREYRGWTDPERIVANVFSLYRQWGVEMPP 300 Query 626 QDLLALL 632 +D L Sbjct 301 EDARDLF 307 >gi|149181234|ref|ZP_01859733.1| fumarylacetoacetate hydrolase family protein [Bacillus sp. SG-1] gi|148851133|gb|EDL65284.1| fumarylacetoacetate hydrolase family protein [Bacillus sp. SG-1] Length=306 Score = 211 bits (538), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 128/317 (41%), Positives = 176/317 (56%), Gaps = 26/317 (8%) Query 1 MKWVTYRSDHGE-RTGVLSGDAIY---------AMPPDV-SLLDLVGRGA---DGLRTAG 46 MK ++Y++ G+ R G L ++ A+P ++ S L+ GL TAG Sbjct 1 MKLISYQNQEGKVRLGFLHNESTLVDVHEASKGALPDNILSFLENSEENLKILQGLETAG 60 Query 47 ERAVRSPAAVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPA 106 + V ALD+VTL APIPRP SIRD F +H++ ++ G ++ WY +P Sbjct 61 K-------GVYALDDVTLKAPIPRPVSIRDFYAFEEHVKTARKNRG--LDVVPEWYEMPV 111 Query 107 FYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDW 166 FYF V G D W D+ELEIA VIG G++++ E AE I GY I NDW Sbjct 112 FYFTNHLAVKGDGDTIHRPKNCRWLDYELEIACVIGKEGRNISKENAEEYIFGYFIMNDW 171 Query 167 SARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGS 226 SARDLQ E ++ +G AKGKD ++GPY+VT DEL PY G + LR+ A VNG + S Sbjct 172 SARDLQREEMKVGLGPAKGKDFATSIGPYIVTKDELGPYREGDRYDLRMTAKVNGRELSS 231 Query 227 GSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVT 286 G+ + ++F E+I AS VTL PG+VFGSGTV T ++E WL GD V Sbjct 232 GNFKSIHYTFAEMIERASADVTLYPGEVFGSGTVGTGCILE---LGTDVHRWLEPGDNVE 288 Query 287 LQVEGLGETRQTVRTSG 303 L++ GLG+ + V+ G Sbjct 289 LEITGLGKLKNEVKEGG 305 >gi|297203287|ref|ZP_06920684.1| hydroxylase [Streptomyces sviceus ATCC 29083] gi|197711373|gb|EDY55407.1| hydroxylase [Streptomyces sviceus ATCC 29083] Length=318 Score = 211 bits (538), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 131/301 (44%), Positives = 168/301 (56%), Gaps = 6/301 (1%) Query 1 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAVRSPAAVVALD 60 M++ TY + ER GV+ ++ +P V++L LV + A A + S V Sbjct 1 MRFATYEYEGVERAGVVRDGVVHPLPEQVTVLTLVEQEALYAAGAEALSAASELTVA--- 57 Query 61 EVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGPYD 120 +V L P+ +PPSIRD + F H+ +++ G + WYR P FYF P G +D Sbjct 58 QVRLLPPL-KPPSIRDFVGFEAHIEGVSKSLDGLEHVPQEWYRAPNFYFTNPHAAYGAHD 116 Query 121 DAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQLRI 180 D P G + DFELE+ AVIG SG+DLT EQA I+GY +FNDWSARDLQ E L + Sbjct 117 DVPVPAGCSVLDFELEVGAVIGRSGRDLTPEQAREHIVGYLVFNDWSARDLQKPEKNLGL 176 Query 181 GQAKGKDSGITLGPYLVTPDELEPYCR-GGKLSLRVIALVNGTVIGSGSTAQMDWSFGEV 239 G +KGKD TLGPYLVT DE+E G L L + +NG +IG + A + W+F E+ Sbjct 177 GFSKGKDFANTLGPYLVTADEVEDRRDPDGFLDLEMTVTLNGELIGRDTLANVSWTFEEM 236 Query 240 IAYASRGVTLTPGDVFGSGTVPTCTLVEHL-RPPESFPGWLHDGDVVTLQVEGLGETRQT 298 IAYASR + PGDV GSGT L EH R E P L GD V L VE LG R Sbjct 237 IAYASRDAWVRPGDVLGSGTCGWGALAEHWGRLGERTPPPLTPGDEVELTVERLGTLRNQ 296 Query 299 V 299 V Sbjct 297 V 297 >gi|229009731|ref|ZP_04166954.1| Fumarylacetoacetate hydrolase [Bacillus mycoides DSM 2048] gi|228751526|gb|EEM01329.1| Fumarylacetoacetate hydrolase [Bacillus mycoides DSM 2048] Length=318 Score = 210 bits (535), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 131/312 (42%), Positives = 174/312 (56%), Gaps = 25/312 (8%) Query 1 MKWVTYRSDHGE-RTGVLSGDAIYAMP-------PDVSLLDLVGRGADGLRTAGERAVRS 52 MK+VT+R E R G L GD + M P S+ + + + + R +++ Sbjct 1 MKFVTFRLPSKEMRAGWLEGDKVIDMNLASDGQLPS-SMFAFLEKADEYVEVL--RNIKN 57 Query 53 PA-AVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDT---WYRIPAFY 108 PA + +L+EV AA IP P SIRD F H++ + GR +D WY IP FY Sbjct 58 PAKGIYSLEEVQFAAAIPNPSSIRDFYAFEQHVKTAR-----GRRGLDVVPEWYDIPVFY 112 Query 109 FACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSA 168 F V+GP D S D+ELEIA VIG G++++ EQAE I GY I NDWSA Sbjct 113 FTNHRAVIGPDDFVIGPKKSKKLDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSA 172 Query 169 RDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGS 228 RDLQ E ++ +G AKGKD +LG YLVT +EL+ Y G + L + A VNG ++ G+ Sbjct 173 RDLQATEMKVGLGPAKGKDFATSLGAYLVTKEELDVYRNGDRYDLEMTAHVNGKILSKGN 232 Query 229 TAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQ 288 + ++F E+I AS VTL PGDV GSGTV T ++E L E WL DGDVV L Sbjct 233 FQDIYYTFAEMIERASEDVTLYPGDVIGSGTVGTGCILE-LGTEE----WLQDGDVVELS 287 Query 289 VEGLGETRQTVR 300 + GLG R TV+ Sbjct 288 ITGLGTLRNTVK 299 >gi|126348270|emb|CAJ89991.1| putative hydroxylase [Streptomyces ambofaciens ATCC 23877] Length=323 Score = 210 bits (534), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 119/253 (48%), Positives = 149/253 (59%), Gaps = 4/253 (1%) Query 59 LDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDTWYRIPAFYFACPSTVLGP 118 + +V L P+ RP S+RD + F +H+ + ++ G + + WY P FYF P + GP Sbjct 61 VSQVRLLPPL-RPASVRDFVTFEEHVEGVRRSVEGTGGVPEQWYAAPTFYFTNPHAIYGP 119 Query 119 YDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSARDLQMLEGQL 178 + P PGSA DFELE+ AVIG G+DLT EQA I+GYT+FNDWSARDLQ E ++ Sbjct 120 GEGVPVPPGSAVLDFELEVGAVIGREGRDLTPEQARDHIVGYTVFNDWSARDLQSAEMKV 179 Query 179 RIGQAKGKDSGITLGPYLVTPDELEPYCRG-GKLSLRVIALVNGTVIGSGSTAQMDWSFG 237 +G KGKD+ TLGPYLVT DELEP+ G L L + A VNG +G + M W+F Sbjct 180 GLGPCKGKDTATTLGPYLVTADELEPHRDADGFLRLALTASVNGETVGEDLLSHMSWTFE 239 Query 238 EVIAYASRGVTLTPGDVFGSGTVPTCTLVEHL--RPPESFPGWLHDGDVVTLQVEGLGET 295 E+ AYASRG + P DV GSGT + L R E P L GD VTL VEGLG Sbjct 240 EMTAYASRGTRVVPADVLGSGTCGNGGCLAELWGRRGERTPPPLRPGDTVTLTVEGLGTL 299 Query 296 RQTVRTSGTPFPL 308 TV P PL Sbjct 300 TNTVVPGVEPVPL 312 >gi|163938232|ref|YP_001643116.1| fumarylacetoacetate (FAA) hydrolase [Bacillus weihenstephanensis KBAB4] gi|163860429|gb|ABY41488.1| fumarylacetoacetate (FAA) hydrolase [Bacillus weihenstephanensis KBAB4] Length=318 Score = 210 bits (534), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 131/312 (42%), Positives = 174/312 (56%), Gaps = 25/312 (8%) Query 1 MKWVTYRSDHGE-RTGVLSGDAIYAMP-------PDVSLLDLVGRGADGLRTAGERAVRS 52 MK+VT+R E R G L GD + M P S+ + + + + R +++ Sbjct 1 MKFVTFRLPSKEMRAGWLEGDKVIDMNLASDGQLPS-SMFAFLEKADEYVEVL--RNIKN 57 Query 53 P-AAVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDT---WYRIPAFY 108 P + +L+EV LAA IP P SIRD F H++ + GR +D WY IP FY Sbjct 58 PEKGIYSLEEVQLAAAIPNPSSIRDFYAFEQHVKTAR-----GRRGLDVVPEWYDIPVFY 112 Query 109 FACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFNDWSA 168 F V+GP D S D+ELEIA VIG G++++ EQAE I GY I NDWSA Sbjct 113 FTNHRAVIGPDDFVIGPKKSKKLDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSA 172 Query 169 RDLQMLEGQLRIGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNGTVIGSGS 228 RDLQ E ++ +G AKGKD +LG YLVT +EL+ Y G + L + A VNG ++ G+ Sbjct 173 RDLQATEMKVGLGPAKGKDFATSLGAYLVTKEELDVYRNGDRYDLEMTAHVNGKILSKGN 232 Query 229 TAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHDGDVVTLQ 288 + ++F E+I AS VTL PGDV GSGTV T ++E L E WL DGDVV L Sbjct 233 FQDIYYTFAEMIERASEDVTLYPGDVIGSGTVGTGCILE-LGTEE----WLQDGDVVELS 287 Query 289 VEGLGETRQTVR 300 + GLG R TV+ Sbjct 288 ITGLGTLRNTVK 299 Lambda K H 0.320 0.138 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1492181782080 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40