BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0957 Length=523 Score E Sequences producing significant alignments: (Bits) Value gi|15608097|ref|NP_215472.1| bifunctional phosphoribosylaminoimi... 1060 0.0 gi|340625970|ref|YP_004744422.1| putative bifunctional purine bi... 1058 0.0 gi|254823460|ref|ZP_05228461.1| bifunctional phosphoribosylamino... 945 0.0 gi|183984512|ref|YP_001852803.1| bifunctional purine biosynthesi... 943 0.0 gi|342860567|ref|ZP_08717218.1| bifunctional phosphoribosylamino... 942 0.0 gi|15826983|ref|NP_301246.1| bifunctional phosphoribosylaminoimi... 942 0.0 gi|118466500|ref|YP_880335.1| bifunctional phosphoribosylaminoim... 940 0.0 gi|118619783|ref|YP_908115.1| bifunctional phosphoribosylaminoim... 940 0.0 gi|8927416|gb|AAF82069.1|AF232750_1 formyltransferase [Mycobacte... 940 0.0 gi|336461423|gb|EGO40294.1| phosphoribosylaminoimidazolecarboxam... 939 0.0 gi|41407001|ref|NP_959837.1| bifunctional phosphoribosylaminoimi... 939 0.0 gi|45645210|sp|Q9RAJ5.2|PUR9_MYCPA RecName: Full=Bifunctional pu... 937 0.0 gi|6179961|gb|AAF05727.1|AF191543_2 PurH [Mycobacterium avium su... 937 0.0 gi|254773961|ref|ZP_05215477.1| bifunctional phosphoribosylamino... 934 0.0 gi|240169365|ref|ZP_04748024.1| bifunctional phosphoribosylamino... 934 0.0 gi|296169718|ref|ZP_06851335.1| bifunctional purine biosynthesis... 931 0.0 gi|289749481|ref|ZP_06508859.1| bifunctional purine biosynthesis... 928 0.0 gi|333989545|ref|YP_004522159.1| bifunctional purine biosynthesi... 896 0.0 gi|108801283|ref|YP_641480.1| bifunctional phosphoribosylaminoim... 870 0.0 gi|126437264|ref|YP_001072955.1| bifunctional phosphoribosylamin... 867 0.0 gi|118471289|ref|YP_889752.1| bifunctional phosphoribosylaminoim... 859 0.0 gi|315442910|ref|YP_004075789.1| IMP cyclohydrolase ;phosphoribo... 854 0.0 gi|145222465|ref|YP_001133143.1| bifunctional phosphoribosylamin... 850 0.0 gi|120405806|ref|YP_955635.1| bifunctional phosphoribosylaminoim... 832 0.0 gi|111022545|ref|YP_705517.1| bifunctional phosphoribosylaminoim... 756 0.0 gi|54026960|ref|YP_121202.1| bifunctional phosphoribosylaminoimi... 755 0.0 gi|226365057|ref|YP_002782840.1| bifunctional phosphoribosylamin... 753 0.0 gi|325676344|ref|ZP_08156023.1| bifunctional purine biosynthesis... 753 0.0 gi|333921236|ref|YP_004494817.1| bifunctional purine biosynthesi... 751 0.0 gi|229495107|ref|ZP_04388853.1| phosphoribosylaminoimidazolecarb... 748 0.0 gi|226307910|ref|YP_002767870.1| bifunctional purine biosynthesi... 747 0.0 gi|343927178|ref|ZP_08766657.1| bifunctional purine biosynthesis... 746 0.0 gi|312138589|ref|YP_004005925.1| phosphoribosylphosphoimidazolec... 746 0.0 gi|326383724|ref|ZP_08205409.1| bifunctional phosphoribosylamino... 745 0.0 gi|262201336|ref|YP_003272544.1| phosphoribosylaminoimidazolecar... 723 0.0 gi|302205786|gb|ADL10128.1| Bifunctional purine biosynthesis pro... 721 0.0 gi|300858064|ref|YP_003783047.1| phosphoribosylaminoimidazolecar... 720 0.0 gi|334696428|gb|AEG81225.1| phosphoribosylaminoimidazolecarboxam... 716 0.0 gi|169628159|ref|YP_001701808.1| bifunctional phospho ribosylami... 716 0.0 gi|337290312|ref|YP_004629333.1| phosphoribosylaminoimidazolecar... 716 0.0 gi|29829987|ref|NP_824621.1| bifunctional phosphoribosylaminoimi... 714 0.0 gi|38233436|ref|NP_939203.1| bifunctional phosphoribosylaminoimi... 714 0.0 gi|134103094|ref|YP_001108755.1| bifunctional phosphoribosylamin... 712 0.0 gi|336326232|ref|YP_004606198.1| phosphoribosylaminoimidazolecar... 712 0.0 gi|25027493|ref|NP_737547.1| bifunctional phosphoribosylaminoimi... 711 0.0 gi|296140985|ref|YP_003648228.1| phosphoribosylaminoimidazolecar... 710 0.0 gi|324998096|ref|ZP_08119208.1| bifunctional phosphoribosylamino... 710 0.0 gi|294814566|ref|ZP_06773209.1| bifunctional phosphoribosylamino... 709 0.0 gi|19552088|ref|NP_600090.1| bifunctional phosphoribosylaminoimi... 703 0.0 gi|302553660|ref|ZP_07306002.1| phosphoribosylaminoimidazolecarb... 701 0.0 >gi|15608097|ref|NP_215472.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium tuberculosis H37Rv] gi|15840381|ref|NP_335418.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium tuberculosis CDC1551] gi|31792146|ref|NP_854639.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium bovis AF2122/97] 80 more sequence titles Length=523 Score = 1060 bits (2740), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/523 (100%), Positives = 523/523 (100%), Gaps = 0/523 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL Sbjct 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG Sbjct 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL Sbjct 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT Sbjct 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA Sbjct 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV Sbjct 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA Sbjct 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE Sbjct 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 Query 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH Sbjct 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 >gi|340625970|ref|YP_004744422.1| putative bifunctional purine biosynthesis protein PURH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase)/inosinemonophosphate cyclohydrolase (IMP cyclohydrolase) (inosinicase) (IMP synthetase) (ATIC) [Mycobacterium canettii CIPT 140010059] gi|340004160|emb|CCC43298.1| putative bifunctional purine biosynthesis protein PURH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (IMP cyclohydrolase) (inosinicase) (IMP synthetase) (ATIC) [Mycobacterium canettii CIPT 140010059] Length=523 Score = 1058 bits (2735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 522/523 (99%), Positives = 522/523 (99%), Gaps = 0/523 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL Sbjct 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG Sbjct 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 ASVDDCVEQIDIGGPAMVRAAAKNHPS AVVTDPLGYHGVLAALRAGGFTLAERKRLASL Sbjct 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSVAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT Sbjct 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA Sbjct 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV Sbjct 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA Sbjct 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE Sbjct 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 Query 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH Sbjct 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 >gi|254823460|ref|ZP_05228461.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium intracellulare ATCC 13950] Length=527 Score = 945 bits (2443), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/527 (87%), Positives = 487/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGL+DLA+GL+AAGVEI+STGSTAK IA+ GIPVT Sbjct 1 MSTDDWRENAKRPIRRALISVYDKTGLIDLARGLAAAGVEIVSTGSTAKNIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHA ALEQLGI AFELVVVNLYPFS+T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAEALEQLGIAAFELVVVNLYPFSET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGAS+DDCVEQIDIGGP+MVRAAAKNHPS AV+TDP GY GVLAA+R GGFTLAERKR Sbjct 121 VDSGASIDDCVEQIDIGGPSMVRAAAKNHPSVAVITDPQGYDGVLAAVRQGGFTLAERKR 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH AEYDIAVASWM+ TLAPEHP AFP+W GRSWRR AMLRYGENPHQQAALY Sbjct 181 LAALAFQHTAEYDIAVASWMESTLAPEHPATAFPKWLGRSWRRSAMLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP+AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHE+TCVAIIKHANPCGIAISS S Sbjct 241 NDPSAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEETCVAIIKHANPCGIAISSAS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P LD+L RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYDPAGLDILTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRP+SGGLL+QQ D+LDAHGDNPANWTLATG PADP TL DL F Sbjct 361 NIRVLVASEPLTGGTELRPVSGGLLVQQRDELDAHGDNPANWTLATGDPADPETLADLAF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AAGV A+VHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 481 DGLETLTAAGVKAIVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 527 >gi|183984512|ref|YP_001852803.1| bifunctional purine biosynthesis protein PurH [Mycobacterium marinum M] gi|238689231|sp|B2HEC3.1|PUR9_MYCMM RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|183177838|gb|ACC42948.1| bifunctional purine biosynthesis protein PurH [Mycobacterium marinum M] Length=523 Score = 943 bits (2438), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/523 (88%), Positives = 483/523 (93%), Gaps = 0/523 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MSTD RRPIRRALISVYDKTGLVDLAQGL+AAGVEI+STGSTAKTIA GIPVT VE+L Sbjct 1 MSTDHIRRPIRRALISVYDKTGLVDLAQGLTAAGVEIVSTGSTAKTIASKGIPVTRVEEL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHPRVHAGLLADLR EH AAL +LG+EAFELVVVNLYPFSQTVESG Sbjct 61 TGFPEVLDGRVKTLHPRVHAGLLADLRNPEHEAALAELGVEAFELVVVNLYPFSQTVESG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 ASVD+CVEQIDIGGP+MVRAAAKNHPS AVVTDP GY GVLAA+ +GGFTLAERK+LASL Sbjct 121 ASVDECVEQIDIGGPSMVRAAAKNHPSVAVVTDPQGYDGVLAAVSSGGFTLAERKKLASL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQH AEYDIAVASWMQ T+APE P FP+WFGR+WRR AMLRYGENPHQQAALY DP Sbjct 181 AFQHTAEYDIAVASWMQSTVAPEQPETDFPRWFGRNWRRQAMLRYGENPHQQAALYADPG 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQ CVAIIKHANPCGIAIS VSVADA Sbjct 241 AWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQKCVAIIKHANPCGIAISEVSVADA 300 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAH CDPLSAYGGVIA NTEVS EMAEYVSTIFTEVIVAP YAP ALD L +KKNIRV Sbjct 301 HRKAHACDPLSAYGGVIACNTEVSPEMAEYVSTIFTEVIVAPAYAPAALDQLTKKKNIRV 360 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 LVA+EP GG+ELRPISGGLL+QQ DQLDA GDNPANWTLATGSPADPATLTDLVFAWR+ Sbjct 361 LVASEPQDGGAELRPISGGLLMQQRDQLDAAGDNPANWTLATGSPADPATLTDLVFAWRS 420 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 CRAVKSNAIVI ADGAT+GVGMGQVNRVDAARLAVERGGERV GAVAASDAFFPFPDGLE Sbjct 421 CRAVKSNAIVIVADGATIGVGMGQVNRVDAARLAVERGGERVNGAVAASDAFFPFPDGLE 480 Query 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 TL AAGV A+VHPGGSVRDEEVT AAAKAG+TLYLTG+RHFAH Sbjct 481 TLTAAGVKAIVHPGGSVRDEEVTAAAAKAGITLYLTGSRHFAH 523 >gi|342860567|ref|ZP_08717218.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium colombiense CECT 3035] gi|342132222|gb|EGT85463.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium colombiense CECT 3035] Length=527 Score = 942 bits (2435), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/527 (87%), Positives = 488/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLVDLAQGL+AAGVEI+STGSTAK IAD GIPVT Sbjct 1 MSTDDWREDAKRPIRRALISVYDKTGLVDLAQGLAAAGVEIVSTGSTAKVIADKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALE+LGI FELVVVNLYPF++T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEELGIAGFELVVVNLYPFTET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGAS+D+CVEQIDIGGP+MVRAAAKNHPS AV+T+P GY GVLAA+RAGGFTLAERK+ Sbjct 121 VDSGASIDECVEQIDIGGPSMVRAAAKNHPSVAVITEPQGYDGVLAAVRAGGFTLAERKK 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LASLAFQH AEYDIAVASWM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQAALY Sbjct 181 LASLAFQHTAEYDIAVASWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSAS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVS+EMAEYVSTIFTEVIVAP Y P AL+VL RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSLEMAEYVSTIFTEVIVAPAYEPAALEVLTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLV +EPL+GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATGSPADPATL DLVF Sbjct 361 NIRVLVGSEPLSGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGSPADPATLADLVF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAGGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV A+VHPGGSVRD+EVT AAA AG++LYLTGARHFAH Sbjct 481 DGLETLTGAGVKAIVHPGGSVRDDEVTAAAANAGISLYLTGARHFAH 527 >gi|15826983|ref|NP_301246.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium leprae TN] gi|221229461|ref|YP_002502877.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium leprae Br4923] gi|7994677|sp|Q9Z5H5.1|PUR9_MYCLE RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|254784012|sp|B8ZU05.1|PUR9_MYCLB RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|4455696|emb|CAB36671.1| putative phosphoribosylaminoimidazolecarboxamide formyltransferase [Mycobacterium leprae] gi|13092530|emb|CAC29669.1| putative phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Mycobacterium leprae] gi|219932568|emb|CAR70254.1| putative phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Mycobacterium leprae Br4923] Length=527 Score = 942 bits (2434), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/520 (89%), Positives = 487/520 (94%), Gaps = 0/520 (0%) Query 4 DDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGF 63 D R+PIRRALISVYDKTGL+DLAQGL+AAGV+I+STGSTAK IAD GI VTPVE+LTGF Sbjct 8 DMARKPIRRALISVYDKTGLIDLAQGLNAAGVDIVSTGSTAKAIADQGIAVTPVEELTGF 67 Query 64 PEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASV 123 PEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGIEAFELVVVNLYPFSQTV+SGA+V Sbjct 68 PEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIEAFELVVVNLYPFSQTVKSGATV 127 Query 124 DDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQ 183 D+CVEQIDIGG +MVRAAAKNHPS AVVTDPLGY GVLAA++ GGFTLAERK LAS+AFQ Sbjct 128 DECVEQIDIGGSSMVRAAAKNHPSVAVVTDPLGYVGVLAAVQGGGFTLAERKMLASMAFQ 187 Query 184 HIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWP 243 HIAEY+IAVASWMQ TLAPE P AFPQWFGRSWRR A+LRYGENPHQQAALY DP+A P Sbjct 188 HIAEYEIAVASWMQSTLAPEQPPTAFPQWFGRSWRRSAILRYGENPHQQAALYSDPSACP 247 Query 244 GLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRK 303 GLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQ+CVAIIKHANPCGIAISS+SVADAHRK Sbjct 248 GLAQAEQLHGKNMSYNNFTDADAAWRAAFDHEQSCVAIIKHANPCGIAISSLSVADAHRK 307 Query 304 AHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVA 363 AHECDPLSAYGGVIAANTEVS+EMAEYVSTIFTEVIVAP YAPGA+DVL+ KKN+RVLVA Sbjct 308 AHECDPLSAYGGVIAANTEVSLEMAEYVSTIFTEVIVAPSYAPGAVDVLSCKKNVRVLVA 367 Query 364 AEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRA 423 + PL GGSELRP+SGGLLIQQ DQLD GDNPANWTLATGSPA PATLTDLVFAWRACRA Sbjct 368 SAPLRGGSELRPVSGGLLIQQPDQLDTAGDNPANWTLATGSPAGPATLTDLVFAWRACRA 427 Query 424 VKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLA 483 VKSNAIVIAADGAT+GVGMGQVNRVDAARLAVERGG+RVRGAV ASDAFFPF DGL+TLA Sbjct 428 VKSNAIVIAADGATIGVGMGQVNRVDAARLAVERGGDRVRGAVVASDAFFPFADGLQTLA 487 Query 484 AAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AAGVTA+VHPGGSVRD EVT AA KAGVTLYLTG RHF H Sbjct 488 AAGVTAIVHPGGSVRDAEVTAAATKAGVTLYLTGVRHFVH 527 >gi|118466500|ref|YP_880335.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium avium 104] gi|118167787|gb|ABK68684.1| bifunctional purine biosynthesis protein PurH [Mycobacterium avium 104] Length=533 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/527 (87%), Positives = 487/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AG+EI+STGSTAK IA+ GIPVT Sbjct 7 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGIEIVSTGSTAKVIAEKGIPVTR 66 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 67 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 126 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 127 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 186 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 187 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 246 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS S Sbjct 247 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSTS 306 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P ALD+L RKK Sbjct 307 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALDILTRKK 366 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DLVF Sbjct 367 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLVF 426 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 427 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 486 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 487 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 533 >gi|118619783|ref|YP_908115.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium ulcerans Agy99] gi|166230887|sp|A0PWC5.1|PUR9_MYCUA RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|118571893|gb|ABL06644.1| bifunctional purine biosynthesis protein PurH [Mycobacterium ulcerans Agy99] Length=523 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/523 (88%), Positives = 481/523 (92%), Gaps = 0/523 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MSTD RRPIRRALISVYDKTGLVDLAQGL+AAGVEI+STGSTAKTIA GIPVT VE+L Sbjct 1 MSTDHIRRPIRRALISVYDKTGLVDLAQGLTAAGVEIVSTGSTAKTIASKGIPVTRVEEL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHPRVHAGLLADLR EH AAL +LG+EAFELVVVNLYPFSQTVESG Sbjct 61 TGFPEVLDGRVKTLHPRVHAGLLADLRNPEHEAALAELGVEAFELVVVNLYPFSQTVESG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 ASVD+CVEQIDIGGP+MVRAAAKNHPS AVVTDP GY GVLAA+R+GGFT AERK+LASL Sbjct 121 ASVDECVEQIDIGGPSMVRAAAKNHPSVAVVTDPQGYDGVLAAVRSGGFTFAERKKLASL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQH AEYDIAVASWMQ T+APE P FP+WFGR+WRR AMLRYGENPHQQAALY DP Sbjct 181 AFQHTAEYDIAVASWMQSTVAPEQPETDFPRWFGRNWRRQAMLRYGENPHQQAALYADPG 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQ CVAIIKHANPCGIAIS VSVADA Sbjct 241 AWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQKCVAIIKHANPCGIAISEVSVADA 300 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAH CDPLSAYGGVIA NTEVS EMAEYVSTIFTEVIVAP YAP ALD L +KKNIRV Sbjct 301 HRKAHACDPLSAYGGVIACNTEVSPEMAEYVSTIFTEVIVAPAYAPAALDQLTKKKNIRV 360 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 LVA+EP GG+ELRPISGGLL+QQ DQLDA GDNPANW LATGSPADPATLTDLVFAWR+ Sbjct 361 LVASEPQDGGAELRPISGGLLMQQRDQLDAAGDNPANWILATGSPADPATLTDLVFAWRS 420 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 CRAVKSNAIVI ADGAT+GVGMGQVNRVDAARLAVERGGERV GAVAASDAFFPFPDGLE Sbjct 421 CRAVKSNAIVIVADGATIGVGMGQVNRVDAARLAVERGGERVNGAVAASDAFFPFPDGLE 480 Query 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 TL AAGV A+VHPGGSVRDEEVT AAAKAG+TLYLTG+RHF H Sbjct 481 TLTAAGVKAIVHPGGSVRDEEVTAAAAKAGITLYLTGSRHFVH 523 >gi|8927416|gb|AAF82069.1|AF232750_1 formyltransferase [Mycobacterium avium subsp. paratuberculosis] Length=535 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/527 (87%), Positives = 488/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 9 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 68 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 69 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 128 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 129 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 188 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 189 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 248 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS+S Sbjct 249 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSIS 308 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P AL++L RKK Sbjct 309 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALEILTRKK 368 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DLVF Sbjct 369 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLVF 428 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 429 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 488 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 489 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 535 >gi|336461423|gb|EGO40294.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium avium subsp. paratuberculosis S397] Length=527 Score = 939 bits (2426), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/527 (87%), Positives = 488/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 1 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 121 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 181 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS+S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSIS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P AL++L RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALEILTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDA+GDNPANWTLATG+PADPATL DLVF Sbjct 361 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAYGDNPANWTLATGAPADPATLADLVF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 481 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 527 >gi|41407001|ref|NP_959837.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395352|gb|AAS03220.1| PurH [Mycobacterium avium subsp. paratuberculosis K-10] Length=533 Score = 939 bits (2426), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/527 (87%), Positives = 487/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 7 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 66 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 67 VEVLTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 126 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 127 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 186 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 187 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 246 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS+S Sbjct 247 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSIS 306 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P AL++L RKK Sbjct 307 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALEILTRKK 366 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DLVF Sbjct 367 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLVF 426 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 427 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 486 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 487 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 533 >gi|45645210|sp|Q9RAJ5.2|PUR9_MYCPA RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase Length=527 Score = 937 bits (2423), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/527 (87%), Positives = 487/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 1 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 61 VEVLTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 121 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 181 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS+S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSIS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P AL++L RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALEILTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DLVF Sbjct 361 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLVF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 481 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 527 >gi|6179961|gb|AAF05727.1|AF191543_2 PurH [Mycobacterium avium subsp. paratuberculosis] Length=527 Score = 937 bits (2421), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/527 (86%), Positives = 486/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 1 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 121 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 181 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS+S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSIS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P AL++L RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALEILTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DLVF Sbjct 361 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLVF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTG RHF H Sbjct 481 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGVRHFVH 527 >gi|254773961|ref|ZP_05215477.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium avium subsp. avium ATCC 25291] Length=527 Score = 934 bits (2415), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/527 (87%), Positives = 485/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGR----RPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MSTDD R RPIRRALISVYDKTGLV+LAQGL+ AGVEI+STGSTAK IA+ GIPVT Sbjct 1 MSTDDWRENAKRPIRRALISVYDKTGLVELAQGLTEAGVEIVSTGSTAKVIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALEQLGI AFELVVVNLYPF++T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIAAFELVVVNLYPFTET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGA +D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+R GGFTLAERKR Sbjct 121 VDSGAGIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRHGGFTLAERKR 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH A+YDIAVA+WM+ TLAPEHP FP+W GRSWRR AMLRYGENPHQQA+LY Sbjct 181 LAALAFQHTADYDIAVATWMESTLAPEHPPTTFPKWLGRSWRRSAMLRYGENPHQQASLY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSTS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVSVEMAEYVSTIFTEVI+AP Y P ALD+L KK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSVEMAEYVSTIFTEVIIAPAYQPAALDILTGKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL+QQ D+LDAHGDNPANWTLATG+PADPATL DL F Sbjct 361 NIRVLVASEPLTGGTELRPISGGLLVQQRDELDAHGDNPANWTLATGAPADPATLADLAF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIVIAA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRVCRAVKSNAIVIAAGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AAA AG+TLYLTGARHFAH Sbjct 481 DGLETLTGAGVKAVVHPGGSVRDDEVTAAAANAGITLYLTGARHFAH 527 >gi|240169365|ref|ZP_04748024.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium kansasii ATCC 12478] Length=527 Score = 934 bits (2413), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/527 (88%), Positives = 485/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 M+ D R+PIRRALISVYDKTGLV+LAQGL AAGVEI+STGSTAKTIA GIPVT VE+L Sbjct 1 MTGDSVRKPIRRALISVYDKTGLVELAQGLMAAGVEIVSTGSTAKTIASKGIPVTRVEEL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHPRVHAGLLADLRK EH AAL++LG+ AFEL+VVNLYPFSQTVESG Sbjct 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKPEHQAALDKLGVAAFELLVVNLYPFSQTVESG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 A +D+CVEQIDIGGP+MVRAAAKN PS AVVTDPLGY GVLAALR+GGF+L ERK+LASL Sbjct 121 AGIDECVEQIDIGGPSMVRAAAKNFPSVAVVTDPLGYDGVLAALRSGGFSLGERKKLASL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQH AEYDIAVASWMQ TLAPE P AFP WF R+WRR A+LRYGENPHQQAALY DP Sbjct 181 AFQHTAEYDIAVASWMQSTLAPEQPETAFPHWFARNWRRQAILRYGENPHQQAALYTDPG 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQ CVAIIKHANPCGIAISSVSVADA Sbjct 241 AWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQICVAIIKHANPCGIAISSVSVADA 300 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAH CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAP YAPGALDVLARKKN+RV Sbjct 301 HRKAHACDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPAYAPGALDVLARKKNVRV 360 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 L+A EP GG+ELRPISGGLL+QQ DQLDA GDNPANWTLATG PA PATLTDLVFAWRA Sbjct 361 LLAPEPQNGGTELRPISGGLLMQQRDQLDAPGDNPANWTLATGEPATPATLTDLVFAWRA 420 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVE----RGGERVRGAVAASDAFFPFP 476 CRAVKSNAIVI ADGATVGVGMGQVNRVDAARLAVE RGGERVRGAVAASDAFFPFP Sbjct 421 CRAVKSNAIVIVADGATVGVGMGQVNRVDAARLAVERGNARGGERVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGL+TL AAGVTA+VHPGGSVRD+EVT AAA+AGVTLYLTGARHFAH Sbjct 481 DGLQTLTAAGVTAIVHPGGSVRDDEVTAAAAEAGVTLYLTGARHFAH 527 >gi|296169718|ref|ZP_06851335.1| bifunctional purine biosynthesis protein PurH [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895615|gb|EFG75312.1| bifunctional purine biosynthesis protein PurH [Mycobacterium parascrofulaceum ATCC BAA-614] Length=527 Score = 931 bits (2407), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/527 (87%), Positives = 486/527 (93%), Gaps = 4/527 (0%) Query 1 MSTDD----GRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 M+TDD +RPIRRALISVYDKTGLV+LA+GL+ AGVEI+STGSTAKTIA+ GIPVT Sbjct 1 MTTDDWPETAKRPIRRALISVYDKTGLVELARGLADAGVEIVSTGSTAKTIAEKGIPVTR 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE+LTGFPEVLDGRVKTLHPRVHAGLLADLRK EHAAALE+LG+ AFELVVVNLYPFS+T Sbjct 61 VEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEELGVAAFELVVVNLYPFSET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 V+SGAS+D+CVEQIDIGGP+MVRAAAKNHPS AVV DP GY GVLAA+R GGFTLAERK+ Sbjct 121 VDSGASIDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPRGYDGVLAAVRHGGFTLAERKK 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LA+LAFQH AEYDIAVA WM+ TLAPEHP FP+W GRSW R AMLRYGENPHQQAALY Sbjct 181 LAALAFQHTAEYDIAVAGWMESTLAPEHPPTTFPKWLGRSWIRSAMLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 DP AWPGLAQAEQLHGK+MSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISS S Sbjct 241 SDPGAWPGLAQAEQLHGKEMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSES 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEVS+EMAEYVSTIFTEVIVAP YAP AL+ L RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVSLEMAEYVSTIFTEVIVAPAYAPEALEALTRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EPL GG+ELRPISGGLL QQ D+LDAHGDNPANWTLATGSPADPATLTDLVF Sbjct 361 NIRVLVASEPLTGGTELRPISGGLLAQQRDELDAHGDNPANWTLATGSPADPATLTDLVF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWRACRAVKSNAIVIA GAT+GVGMGQVNRVDAARLAVERGG+RVRGAVAASDAFFPFP Sbjct 421 AWRACRAVKSNAIVIAGGGATIGVGMGQVNRVDAARLAVERGGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AAGV A+VHPGGSVRD+EVT AA AGVTLYLTGARHFAH Sbjct 481 DGLETLTAAGVKAIVHPGGSVRDDEVTAAATNAGVTLYLTGARHFAH 527 >gi|289749481|ref|ZP_06508859.1| bifunctional purine biosynthesis protein purH [Mycobacterium tuberculosis T92] gi|289690068|gb|EFD57497.1| bifunctional purine biosynthesis protein purH [Mycobacterium tuberculosis T92] Length=458 Score = 928 bits (2399), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/458 (99%), Positives = 458/458 (100%), Gaps = 0/458 (0%) Query 66 VLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDD 125 +LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDD Sbjct 1 MLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDD 60 Query 126 CVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHI 185 CVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHI Sbjct 61 CVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHI 120 Query 186 AEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGL 245 AEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGL Sbjct 121 AEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGL 180 Query 246 AQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAH 305 AQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAH Sbjct 181 AQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAH 240 Query 306 ECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAE 365 ECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAE Sbjct 241 ECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAE 300 Query 366 PLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVK 425 PLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVK Sbjct 301 PLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVK 360 Query 426 SNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAA 485 SNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAA Sbjct 361 SNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAA 420 Query 486 GVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 GVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH Sbjct 421 GVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 458 >gi|333989545|ref|YP_004522159.1| bifunctional purine biosynthesis protein PurH [Mycobacterium sp. JDM601] gi|333485513|gb|AEF34905.1| bifunctional purine biosynthesis protein PurH [Mycobacterium sp. JDM601] Length=521 Score = 896 bits (2316), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/519 (85%), Positives = 473/519 (92%), Gaps = 0/519 (0%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 DG+RPIRRALISVYDKTGLVDLA GL AAGV+I+STGSTAKTIA GIPVTPVEQLTGFP Sbjct 3 DGKRPIRRALISVYDKTGLVDLATGLHAAGVDIVSTGSTAKTIAAKGIPVTPVEQLTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 EVLDGRVKTLHPRVHAGLLADLRK EHAAAL +L I FELVVVNLYPFS+TV+SGA +D Sbjct 63 EVLDGRVKTLHPRVHAGLLADLRKPEHAAALGELDIAPFELVVVNLYPFSETVDSGAGMD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 +CVEQIDIGGP+M+RAAAKNHPS AVV DPLGY GVLAA+ AGGFTLAERKRLASLAF+H Sbjct 123 ECVEQIDIGGPSMIRAAAKNHPSVAVVVDPLGYDGVLAAVNAGGFTLAERKRLASLAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 AEYD+AVA WM TLAPE P P+WFGRS+RR A LRYGENPHQQAAL+ D AWPG Sbjct 183 TAEYDVAVAGWMSSTLAPEEPRQPMPEWFGRSYRRAAQLRYGENPHQQAALFCDGGAWPG 242 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQA+QLHGK+MSYNNFTDADAAWRAAFDHE+TCVAIIKHANPCGIAISS+SVADAHRKA Sbjct 243 LAQADQLHGKEMSYNNFTDADAAWRAAFDHEETCVAIIKHANPCGIAISSISVADAHRKA 302 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 HECDPLSA+GGVIAANTEVS EMAEYVSTIFTEVIVAP Y GA+++LARKKNIRVL+A+ Sbjct 303 HECDPLSAFGGVIAANTEVSAEMAEYVSTIFTEVIVAPAYESGAVEILARKKNIRVLLAS 362 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 EPL GG E R ISGGLL+Q D LDA GDNP NWTLATGSPADPAT+ DLVFAWR+CRAV Sbjct 363 EPLRGGVEWRQISGGLLMQSRDGLDAAGDNPVNWTLATGSPADPATMADLVFAWRSCRAV 422 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAA 484 KSNAIV+AA+GATVGVGMGQVNRVDAARLAVERGG+RV GAVAASDAFFPFPDGL+TL Sbjct 423 KSNAIVVAANGATVGVGMGQVNRVDAARLAVERGGDRVAGAVAASDAFFPFPDGLQTLTG 482 Query 485 AGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AGVTA+VHPGGSVRD+EVT AAA+AGVTLYLTGARHFAH Sbjct 483 AGVTAIVHPGGSVRDDEVTAAAAEAGVTLYLTGARHFAH 521 >gi|108801283|ref|YP_641480.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium sp. MCS] gi|119870434|ref|YP_940386.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium sp. KMS] gi|123368768|sp|Q1B3W0.1|PUR9_MYCSS RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|166230885|sp|A1UL88.1|PUR9_MYCSK RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|108771702|gb|ABG10424.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Mycobacterium sp. MCS] gi|119696523|gb|ABL93596.1| IMP cyclohydrolase [Mycobacterium sp. KMS] Length=527 Score = 870 bits (2247), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/527 (81%), Positives = 466/527 (89%), Gaps = 4/527 (0%) Query 1 MSTDDG----RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MS D G +RPIRRALISVYDKTGL+DLA+GL AGV+I+STGSTAKTIAD GIPVTP Sbjct 1 MSGDQGQAGAKRPIRRALISVYDKTGLIDLARGLHEAGVDIVSTGSTAKTIADKGIPVTP 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE +TGFPEVLDGRVKTLHP +HAGLLAD RK EH AL +LGI F+LVVVNLYPFS+T Sbjct 61 VEFVTGFPEVLDGRVKTLHPHIHAGLLADTRKPEHVEALAKLGIAPFDLVVVNLYPFSET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 VESGASVD+CVEQIDIGGP+MVRAAAKNHPS AVV +P GY GVLAA+R GGFTLAERK Sbjct 121 VESGASVDECVEQIDIGGPSMVRAAAKNHPSVAVVVEPNGYDGVLAAVRTGGFTLAERKI 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LASLAF+H AEYD+AVASWM TLAPE P P W G +WRR A+LRYGENPHQQAALY Sbjct 181 LASLAFRHTAEYDVAVASWMGSTLAPEEPAQKLPAWVGGTWRRAAVLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 D TAWPGLAQAEQLHGK+MSYNN+TDADAAWRAAFDHE+ CVAIIKHANPCGIAISSVS Sbjct 241 RDATAWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDHEEICVAIIKHANPCGIAISSVS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIA N+ VSVEMAE V+ IFTEVIVAP Y PGA+++L+RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIATNSSVSVEMAETVADIFTEVIVAPAYEPGAVEILSRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIR+LVAA+P G+ELRPISGGLL+QQ D LDA GD+P NWTLATG PADPATL +L F Sbjct 361 NIRILVAAQPPTTGTELRPISGGLLLQQRDALDADGDDPVNWTLATGEPADPATLANLKF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR+CRAVKSNAIV+ ADGATVGVGMGQVNRVDAARLAV+R G+RVRGAVAASDAFFPFP Sbjct 421 AWRSCRAVKSNAIVVVADGATVGVGMGQVNRVDAARLAVQRAGDRVRGAVAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV A+VHPGGS+RD+ VTEAAAKAG++LYLTGARHFAH Sbjct 481 DGLETLTEAGVKAIVHPGGSMRDDVVTEAAAKAGISLYLTGARHFAH 527 >gi|126437264|ref|YP_001072955.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium sp. JLS] gi|166230884|sp|A3Q5N7.1|PUR9_MYCSJ RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|126237064|gb|ABO00465.1| IMP cyclohydrolase [Mycobacterium sp. JLS] Length=527 Score = 867 bits (2240), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/527 (80%), Positives = 466/527 (89%), Gaps = 4/527 (0%) Query 1 MSTDDG----RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTP 56 MS D G +RPIRRALISVYDK+GL+DLA+GL AGV+I+STGSTAKTIAD GIPVTP Sbjct 1 MSGDQGQAGAKRPIRRALISVYDKSGLIDLARGLHEAGVDIVSTGSTAKTIADKGIPVTP 60 Query 57 VEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQT 116 VE +TGFPEVLDGRVKTLHP +HAGLLAD RK EH AL +LGI F+LVVVNLYPFS+T Sbjct 61 VEFVTGFPEVLDGRVKTLHPHIHAGLLADTRKPEHVEALAKLGIAPFDLVVVNLYPFSET 120 Query 117 VESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKR 176 VESGASVD+CVEQIDIGGP+MVRAAAKNHPS AVV +P GY GVLAA+R GGFTLAERK Sbjct 121 VESGASVDECVEQIDIGGPSMVRAAAKNHPSVAVVVEPNGYDGVLAAVRTGGFTLAERKI 180 Query 177 LASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY 236 LASLAF+H AEYD+AVASWM TLAPE P P W G +WRR A+LRYGENPHQQAALY Sbjct 181 LASLAFRHTAEYDVAVASWMGSTLAPEEPAQKLPAWVGGTWRRAAVLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 D TAWPGLAQAEQLHGK+MSYNN+TDADAAWRAAFDHE+ CVAIIKHANPCGIAISSVS Sbjct 241 RDATAWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDHEEICVAIIKHANPCGIAISSVS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIA N+ VSVEMAE V+ IFTEVIVAP Y PGA+++L+RKK Sbjct 301 VADAHRKAHECDPLSAFGGVIATNSSVSVEMAETVADIFTEVIVAPAYEPGAVEILSRKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIR+L+AA+P G+ELRPISGGLL+QQ D LDA GD+P NWTLATG PADPATL +L F Sbjct 361 NIRILLAAQPPTTGTELRPISGGLLLQQRDALDADGDDPVNWTLATGEPADPATLANLKF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR+CRAVKSNAIV+ ADGATVGVGMGQVNRVDAARLAV+R G+RVRGA+AASDAFFPFP Sbjct 421 AWRSCRAVKSNAIVVVADGATVGVGMGQVNRVDAARLAVQRAGDRVRGAIAASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV A+VHPGGS+RD+ VTEAAAKAG++LYLTGARHFAH Sbjct 481 DGLETLTEAGVKAIVHPGGSMRDDVVTEAAAKAGISLYLTGARHFAH 527 >gi|118471289|ref|YP_889752.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium smegmatis str. MC2 155] gi|118172576|gb|ABK73472.1| bifunctional purine biosynthesis protein PurH [Mycobacterium smegmatis str. MC2 155] Length=527 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/524 (80%), Positives = 463/524 (89%), Gaps = 7/524 (1%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 ++P+RRALISVYDKTGL DLA+GL AGV I+STGSTAKTIA G+PVTPVEQ+TGFPEV Sbjct 4 KKPVRRALISVYDKTGLADLARGLHQAGVAIVSTGSTAKTIAAAGVPVTPVEQVTGFPEV 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHPRVHAGLLAD RK EH AAL++L +EAFELVVVNLYPFS+TV SGASVD+C Sbjct 64 LDGRVKTLHPRVHAGLLADTRKPEHLAALKELDVEAFELVVVNLYPFSETVASGASVDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+RAGGFTLAERK+LAS+AF+H A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRAGGFTLAERKKLASVAFRHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVA-------AFPQWFGRSWRRVAMLRYGENPHQQAALYGDP 239 EYD+AVASWM TL+PE A + PQWF +W R A+LRYGENPHQ+AA+Y D Sbjct 184 EYDVAVASWMGSTLSPEEGSAEGGAVEPSLPQWFAGTWHRAAVLRYGENPHQKAAVYRDN 243 Query 240 TAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVAD 299 AWPGLAQAEQLHGK+MSYNN+TDADAAWRAAFDHEQTCVAIIKHANPCGIAISS SVAD Sbjct 244 AAWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSTSVAD 303 Query 300 AHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIR 359 AHRKAHECDPLSA+GGVIAANTEVSVEMAE +S IFTEVI+AP Y PGA++VLARKKNIR Sbjct 304 AHRKAHECDPLSAFGGVIAANTEVSVEMAETISEIFTEVIIAPAYEPGAVEVLARKKNIR 363 Query 360 VLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWR 419 +LVA++P GG+E+R ISGGLL+QQ D LDA GD+P NWTLATG PADP TL DLVFAWR Sbjct 364 ILVASQPPIGGTEVRQISGGLLLQQRDALDADGDDPNNWTLATGEPADPKTLEDLVFAWR 423 Query 420 ACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGL 479 ACRAVKSNAIV+A DGATVGVGMGQVNRVDAA+LAV+RGG+RV GAVAASDAFFPFPDGL Sbjct 424 ACRAVKSNAIVVARDGATVGVGMGQVNRVDAAKLAVQRGGDRVAGAVAASDAFFPFPDGL 483 Query 480 ETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 + L A V A+VHPGGSVRD EVT AA AG+TLYLTGARHFAH Sbjct 484 QVLTEADVKAIVHPGGSVRDAEVTAAAELAGITLYLTGARHFAH 527 >gi|315442910|ref|YP_004075789.1| IMP cyclohydrolase ;phosphoribosylaminoimidazolecarboxamide formyltransferase [Mycobacterium sp. Spyr1] gi|315261213|gb|ADT97954.1| IMP cyclohydrolase ;phosphoribosylaminoimidazolecarboxamide formyltransferase [Mycobacterium sp. Spyr1] Length=533 Score = 854 bits (2206), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/533 (80%), Positives = 457/533 (86%), Gaps = 10/533 (1%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MS +D RRPIRRALISVYDK+GL LAQGL AAGV+I+STGSTAKTIA GIPVTPVE + Sbjct 1 MSDNDFRRPIRRALISVYDKSGLEALAQGLHAAGVDIVSTGSTAKTIASAGIPVTPVEDV 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHP VHAGLLAD RK+EH ALEQLG+ AFELVVVNLYPF+QTV SG Sbjct 61 TGFPEVLDGRVKTLHPHVHAGLLADQRKAEHVTALEQLGVAAFELVVVNLYPFTQTVNSG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 A VD+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+RAGGFT ERK+LA+L Sbjct 121 AGVDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRAGGFTYTERKKLAAL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHP----------VAAFPQWFGRSWRRVAMLRYGENPH 230 AF+H AEYD+AVASWM LAPE VA P W G ++RR A+LRYGENPH Sbjct 181 AFRHTAEYDVAVASWMGSVLAPEDSASEDDGAADDVAQLPPWLGSTFRRSAVLRYGENPH 240 Query 231 QQAALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGI 290 Q+AALYGD WPGLAQAEQLHGK+MSYNN+TDADAAWRAAFD E CVAIIKHANPCGI Sbjct 241 QKAALYGDEGGWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDQEAICVAIIKHANPCGI 300 Query 291 AISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALD 350 AISSVSVADAHRKAHECDPLSA+GGVIAANTEV+VEMAE V+ IFTEVI+AP Y PGA+D Sbjct 301 AISSVSVADAHRKAHECDPLSAFGGVIAANTEVTVEMAETVAGIFTEVIIAPAYEPGAVD 360 Query 351 VLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPAT 410 VL KKNIRVLVA+EP GG+E R ISGGLL+QQ D LDA GD+P NWTLATG+PADP T Sbjct 361 VLKGKKNIRVLVASEPQPGGTEFRQISGGLLLQQRDALDASGDDPNNWTLATGAPADPDT 420 Query 411 LTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASD 470 L DLVFAWR CRAVKSNAIV+A DGATVGVGMGQVNRVDAARLAVER GER R AV ASD Sbjct 421 LADLVFAWRTCRAVKSNAIVLAKDGATVGVGMGQVNRVDAARLAVERAGERTRDAVGASD 480 Query 471 AFFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AFFPFPDGL+TL AGV AVVHPGGSVRD+EVT AA AG+TLYLTGARHFAH Sbjct 481 AFFPFPDGLQTLIDAGVKAVVHPGGSVRDDEVTAAAEAAGITLYLTGARHFAH 533 >gi|145222465|ref|YP_001133143.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium gilvum PYR-GCK] gi|145214951|gb|ABP44355.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Mycobacterium gilvum PYR-GCK] Length=531 Score = 850 bits (2196), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/531 (80%), Positives = 456/531 (86%), Gaps = 8/531 (1%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MS +D RRPIRRALISVYDK+GL LAQGL AAGV+I+STGSTAK IA GIPVTPVE + Sbjct 1 MSDNDFRRPIRRALISVYDKSGLEALAQGLHAAGVDIVSTGSTAKNIAAAGIPVTPVEDV 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPEVLDGRVKTLHP VHAGLLAD RK+EH ALEQLG+ AFELVVVNLYPF+QTV SG Sbjct 61 TGFPEVLDGRVKTLHPHVHAGLLADQRKAEHVTALEQLGVAAFELVVVNLYPFTQTVNSG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 A VD+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+RAGGFT ERK+LA+L Sbjct 121 AGVDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRAGGFTYTERKKLAAL 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHP--------VAAFPQWFGRSWRRVAMLRYGENPHQQ 232 AF+H AEYD+AVASWM LAPE VA P W G ++RR A+LRYGENPHQ+ Sbjct 181 AFRHTAEYDVAVASWMGSVLAPEDDAPEGAADDVAQLPPWLGSTFRRSAVLRYGENPHQK 240 Query 233 AALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAI 292 AALYGD WPGLAQAEQLHGK+MSYNN+TDADAAWRAAFD E CVAIIKHANPCGIAI Sbjct 241 AALYGDEGGWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDQEAICVAIIKHANPCGIAI 300 Query 293 SSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVL 352 SSVSVADAHRKAHECDPLSA+GGVIAANTEV+VEMAE V+ IFTEVI+AP Y PGA+DVL Sbjct 301 SSVSVADAHRKAHECDPLSAFGGVIAANTEVTVEMAETVAGIFTEVIIAPAYEPGAVDVL 360 Query 353 ARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLT 412 KKNIRVLVA+EP GG+E R ISGGLL+QQ D LDA GD+P NWTLATG+PADP TL Sbjct 361 KGKKNIRVLVASEPQPGGTEFRQISGGLLLQQRDALDASGDDPNNWTLATGAPADPDTLA 420 Query 413 DLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAF 472 DLVFAWR CRAVKSNAIV+A DGATVGVGMGQVNRVDAARLAVER GER R AV ASDAF Sbjct 421 DLVFAWRTCRAVKSNAIVLAKDGATVGVGMGQVNRVDAARLAVERAGERTRDAVGASDAF 480 Query 473 FPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 FPFPDGL+TL AGV AVVHPGGSVRD+EVT AA AG+TLYLTGARHFAH Sbjct 481 FPFPDGLQTLIDAGVKAVVHPGGSVRDDEVTAAAEAAGITLYLTGARHFAH 531 >gi|120405806|ref|YP_955635.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium vanbaalenii PYR-1] gi|119958624|gb|ABM15629.1| IMP cyclohydrolase [Mycobacterium vanbaalenii PYR-1] Length=527 Score = 832 bits (2148), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/527 (79%), Positives = 451/527 (86%), Gaps = 4/527 (0%) Query 1 MSTDDG--RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVE 58 MS +D RRPIRRALISVYDKTGLV LAQGL AAGV+I+STGSTAKTIA GIPVTPVE Sbjct 1 MSDNDDLFRRPIRRALISVYDKTGLVPLAQGLHAAGVDIVSTGSTAKTIAGAGIPVTPVE 60 Query 59 QLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVE 118 +TGFPEVLDGRVKTLHP VHAGLLAD RK+EH AAL +LG+ AFELVVVNLYPF+QTV Sbjct 61 DVTGFPEVLDGRVKTLHPHVHAGLLADQRKAEHVAALAELGVTAFELVVVNLYPFTQTVN 120 Query 119 SGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLA 178 SGA D+CVEQIDIGGP+MVRAAAKNHPS AVV DPLGY GVLAA+RAGGFT +ERK+LA Sbjct 121 SGADEDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPLGYDGVLAAVRAGGFTYSERKKLA 180 Query 179 SLAFQHIAEYDIAVASWMQQTLAPEHPVAA--FPQWFGRSWRRVAMLRYGENPHQQAALY 236 +LAF+H AEYD+AVASWM+ LAPE + P W G ++RR A+LRYGENPHQQAALY Sbjct 181 ALAFRHTAEYDVAVASWMESVLAPEAEATSGDLPPWLGATFRRAAVLRYGENPHQQAALY 240 Query 237 GDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVS 296 D WPGLAQAEQLHGK+MSYNN+TDADAAWRAAFDHE CVAIIKHANPCGIAIS VS Sbjct 241 RDDGGWPGLAQAEQLHGKEMSYNNYTDADAAWRAAFDHEDICVAIIKHANPCGIAISPVS 300 Query 297 VADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKK 356 VADAHRKAHECDPLSA+GGVIAANTEV+VEMAE V+ IFTEVI+AP Y PGA++VL+ KK Sbjct 301 VADAHRKAHECDPLSAFGGVIAANTEVTVEMAETVAGIFTEVIIAPAYEPGAVEVLSGKK 360 Query 357 NIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVF 416 NIRVLVA+EP GG+E R +SGGLL+QQ D LDA GDNP WTLA G ADP TL DL F Sbjct 361 NIRVLVASEPQRGGTEFRQVSGGLLLQQRDALDAAGDNPNTWTLAAGPAADPDTLADLAF 420 Query 417 AWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFP 476 AWR CRAVKSNAIV+A DGATVGVGMGQVNRVDAARLAVER G R GAV ASDAFFPFP Sbjct 421 AWRTCRAVKSNAIVLARDGATVGVGMGQVNRVDAARLAVERAGGRSSGAVGASDAFFPFP 480 Query 477 DGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 DGLETL AGV AVVHPGGSVRD+EVT AA G+TLYLTGARHFAH Sbjct 481 DGLETLIRAGVKAVVHPGGSVRDDEVTAAAEADGITLYLTGARHFAH 527 >gi|111022545|ref|YP_705517.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodococcus jostii RHA1] gi|110822075|gb|ABG97359.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/ IMP cyclohydrolase [Rhodococcus jostii RHA1] Length=518 Score = 756 bits (1951), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/517 (73%), Positives = 427/517 (83%), Gaps = 2/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+ +RRAL+SVYDKTGLV+LA GL AGVE++STGSTA IAD GIPVTPVE LTGFPE Sbjct 4 RKAVRRALVSVYDKTGLVELATGLHKAGVELVSTGSTAAKIADAGIPVTPVEALTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 L+GRVKTLHPRVHAG+LAD RK EH A LE+LGIEAF+LVVVNLYPF+QTV SGA+ D+C Sbjct 64 LEGRVKTLHPRVHAGILADTRKPEHLAQLEELGIEAFQLVVVNLYPFTQTVASGATPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y VL A+ GGFTL ER LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPARYDDVLTAVADGGFTLPERTALAAQAFQHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM TL E + FP+W G +W R A+LRYGENPHQ AALY +P A GLA Sbjct 184 SYDVAVASWMTSTLV-EPGDSQFPEWAGATWDRSAVLRYGENPHQAAALYVNPAAPAGLA 242 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 QAEQLHGK+MSYNN+TD DAAWRAAFD + VAIIKHANPCGIA+ + +A+AHRKAH Sbjct 243 QAEQLHGKEMSYNNYTDGDAAWRAAFDFSEPAVAIIKHANPCGIAVGA-DIAEAHRKAHA 301 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDP+SAYGGVIAAN E++VEMAE V+ IFTEVI+AP YA GAL VL RKKNIRVL+A P Sbjct 302 CDPVSAYGGVIAANREITVEMAEQVAEIFTEVIIAPSYADGALGVLQRKKNIRVLLAQAP 361 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 A G ELRP+SGG L+Q+ D LDA GD+PANWTLA G AD TL DL FAWRACR+VKS Sbjct 362 TATGIELRPVSGGALLQERDVLDAEGDDPANWTLAVGDAADEQTLKDLEFAWRACRSVKS 421 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAI++A+DGA+VGVGMGQVNRVD+A LAV+R G+RV G+V ASDAFFPFPDGL+ LA AG Sbjct 422 NAILLASDGASVGVGMGQVNRVDSAHLAVQRAGDRVVGSVGASDAFFPFPDGLQVLANAG 481 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V AVV PGGSVRD EV +AA +AG+T+YLTGARHFAH Sbjct 482 VKAVVQPGGSVRDNEVIDAAKEAGITMYLTGARHFAH 518 >gi|54026960|ref|YP_121202.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Nocardia farcinica IFM 10152] gi|54018468|dbj|BAD59838.1| putative phosphoribosylaminoimidazole carboxy formyl formyltransferase/inosine-monophosphate cyclohydrolase [Nocardia farcinica IFM 10152] Length=523 Score = 755 bits (1950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/521 (72%), Positives = 427/521 (82%), Gaps = 5/521 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+PIRRAL+SVYDKTGLV+LA GL AAGVE++STGSTA IAD GIPVT VE+LTGFPE Sbjct 4 RKPIRRALVSVYDKTGLVELATGLHAAGVELVSTGSTAGRIADAGIPVTKVEELTGFPET 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHPRVHAG+LAD RK EH L +LG+EAF+LVVVNLYPF+QTV SGAS D+C Sbjct 64 LDGRVKTLHPRVHAGILADTRKPEHLDQLTELGVEAFQLVVVNLYPFTQTVASGASPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV D Y VLAA+RAGGFTLA+R LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDAGDYDDVLAAVRAGGFTLAQRTALAAKAFQHTA 183 Query 187 EYDIAVASWMQQTLAP----EHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAW 242 YD+AVASW+ LAP + P +P W G SW R A+LRYGENPHQ AALY Sbjct 184 GYDVAVASWLTGVLAPSVADQPPSTPYPAWIGGSWERAAVLRYGENPHQSAALYTSNDGS 243 Query 243 PGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHR 302 PGLAQA+QLHGK+MSYNN+TDADAAWRAA+DHE VAIIKHANPCGIAI + +A+AHR Sbjct 244 PGLAQAQQLHGKEMSYNNYTDADAAWRAAYDHEAPAVAIIKHANPCGIAIGA-DIAEAHR 302 Query 303 KAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLV 362 KAH CDP+SA+GGVIAAN EV+VEMAE V+ IFTEVIVAP YA GA++VL RKKN+R+L+ Sbjct 303 KAHACDPVSAFGGVIAANREVTVEMAEQVADIFTEVIVAPSYADGAVEVLQRKKNVRILI 362 Query 363 AAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACR 422 A P G ELRPISGG L+QQ D LDA GD+PANWTL G+ AD TL DL FAWRACR Sbjct 363 AEPPQRAGVELRPISGGALLQQRDILDAEGDDPANWTLVAGTAADEQTLADLAFAWRACR 422 Query 423 AVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETL 482 AVKSNAI++A+DGA+VGVGMGQVNRVDA +LAV R G+R +G+VAASDAFFPFPDG + L Sbjct 423 AVKSNAILLASDGASVGVGMGQVNRVDAVQLAVRRAGDRAKGSVAASDAFFPFPDGPQQL 482 Query 483 AAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AGV A+V PGGSVRD+E + A +AGVTLYLTG+RHFAH Sbjct 483 IQAGVRAIVQPGGSVRDQETIDLAREAGVTLYLTGSRHFAH 523 >gi|226365057|ref|YP_002782840.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodococcus opacus B4] gi|226243547|dbj|BAH53895.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodococcus opacus B4] Length=518 Score = 753 bits (1945), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/517 (72%), Positives = 426/517 (83%), Gaps = 2/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+ +RRAL+SVYDKTGLV+LA GL AGVE++STGSTA IAD GIPVTPVE LTGFPE Sbjct 4 RKAVRRALVSVYDKTGLVELATGLHKAGVELVSTGSTAAKIADAGIPVTPVEALTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 L+GRVKTLHPRVHAG+LAD RK EH A LE+LGIEAF+LVVVNLYPF+QTV SGA+ D+C Sbjct 64 LEGRVKTLHPRVHAGVLADTRKPEHLAQLEELGIEAFQLVVVNLYPFTQTVASGATPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y VL A+ GGFTL ER LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPARYDNVLTAIADGGFTLPERTALAAQAFQHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM TL + + FP+W G +W R A+LRYGENPHQ AALY + A GLA Sbjct 184 SYDVAVASWMTSTLV-DSGDSQFPEWAGATWDRSAVLRYGENPHQAAALYVNSAAPAGLA 242 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 QAEQLHGK+MSYNN+TD DAAWRAAFD + VAIIKHANPCGIA+ + +A+AHRKAH Sbjct 243 QAEQLHGKEMSYNNYTDGDAAWRAAFDFSEPAVAIIKHANPCGIAVGA-DIAEAHRKAHA 301 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDP+SAYGGVIAAN E++VEMAE V+ IFTEVI+AP YA GAL VL RKKN+RVL+A P Sbjct 302 CDPVSAYGGVIAANREITVEMAEQVAEIFTEVIIAPSYADGALGVLQRKKNVRVLLAQAP 361 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 A G ELRP+SGG L+Q+ D LDA GD+PANWTLA G AD TL DL FAWRACR+VKS Sbjct 362 TATGIELRPVSGGALLQERDVLDAEGDDPANWTLAVGDAADEQTLKDLEFAWRACRSVKS 421 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAI++AADGA+VGVGMGQVNRVD+A LAV+R G+RV G+V ASDAFFPFPDGL+ LA AG Sbjct 422 NAILLAADGASVGVGMGQVNRVDSAHLAVQRAGDRVVGSVGASDAFFPFPDGLQVLANAG 481 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V AVV PGGSVRD EV +AA +AG+T+YLTGARHFAH Sbjct 482 VKAVVQPGGSVRDNEVIDAAKEAGITMYLTGARHFAH 518 >gi|325676344|ref|ZP_08156023.1| bifunctional purine biosynthesis protein PurH [Rhodococcus equi ATCC 33707] gi|325552905|gb|EGD22588.1| bifunctional purine biosynthesis protein PurH [Rhodococcus equi ATCC 33707] Length=528 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/526 (71%), Positives = 428/526 (82%), Gaps = 10/526 (1%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+ +RRAL+SVYDKTGLV+LA GL AGVE++STGSTA IA+ GIPVT VE LTGFPE Sbjct 4 RKAVRRALVSVYDKTGLVELATGLHQAGVELVSTGSTAAKIAEAGIPVTKVEDLTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 L+GRVKTLHPRVHAG+LAD RK EH A LE+LGIEAF+LV+VNLYPF+QTV SGA+ D+C Sbjct 64 LEGRVKTLHPRVHAGVLADTRKPEHLAQLEELGIEAFQLVIVNLYPFTQTVASGATPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y GVLAA+ AGGF L ER LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPAKYEGVLAAVEAGGFNLFERTALAAQAFQHTA 183 Query 187 EYDIAVASWMQ----QTLAP-----EHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYG 237 YD+AVA+WM QT+AP + ++ FP+W G +W R A+LRYGENPHQ AALY Sbjct 184 SYDVAVATWMTESLVQTVAPSEETDDSALSKFPRWVGATWNRSAVLRYGENPHQAAALYD 243 Query 238 DPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSV 297 P GLAQA+Q HGK+MSYNN+TD DAAWRAA+DH + VAIIKHANPCGIA+ + + Sbjct 244 SPAGPAGLAQAKQFHGKEMSYNNYTDGDAAWRAAYDHAEPAVAIIKHANPCGIAVGA-DI 302 Query 298 ADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKN 357 A+AHRKAH CDP+SA+GGVIAAN EV+VEMAE V+ IFTEV++AP YAPGA++VLARKKN Sbjct 303 AEAHRKAHACDPVSAFGGVIAANREVTVEMAEQVADIFTEVVIAPSYAPGAVEVLARKKN 362 Query 358 IRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFA 417 +RVL AA P G ELRPISGG L+Q D LDA GDN ANWTL G AD TL DL FA Sbjct 363 VRVLEAAAPTETGIELRPISGGALLQDRDVLDADGDNSANWTLVVGDAADEKTLADLEFA 422 Query 418 WRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPD 477 WRACRAVKSNAI++A DGA+VGVGMGQVNRVD+A LAV+R G+R +G+VAASDAFFPFPD Sbjct 423 WRACRAVKSNAILLANDGASVGVGMGQVNRVDSAHLAVQRAGDRAKGSVAASDAFFPFPD 482 Query 478 GLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 GL+ L AGV AVV PGGSVRD EV EAA +AGVTLYLTGARHFAH Sbjct 483 GLQVLLDAGVRAVVQPGGSVRDNEVIEAAREAGVTLYLTGARHFAH 528 >gi|333921236|ref|YP_004494817.1| bifunctional purine biosynthesis protein purH [Amycolicicoccus subflavus DQS3-9A1] gi|333483457|gb|AEF42017.1| Bifunctional purine biosynthesis protein purH [Amycolicicoccus subflavus DQS3-9A1] Length=530 Score = 751 bits (1939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/521 (72%), Positives = 421/521 (81%), Gaps = 4/521 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R +RRALISVYDK+GL DLA+GL++AGVEI+STGSTA IA G+ VTPVE+LTGFPE Sbjct 10 RIAVRRALISVYDKSGLEDLARGLASAGVEIVSTGSTASRIAAAGVDVTPVEELTGFPET 69 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHP VHAG+LAD RK EH L++LG+EAF+LVVVNLYPF++TV SGA+ D+C Sbjct 70 LDGRVKTLHPHVHAGILADTRKHEHLEQLDELGVEAFQLVVVNLYPFTETVASGATEDEC 129 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS VV DP Y VLAA+ AGGFT+ ER LA+ AFQH A Sbjct 130 VEQIDIGGPSMVRAAAKNHPSVGVVVDPGQYERVLAAVEAGGFTMQERIELAADAFQHTA 189 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM A + FP+W G +W R + LRYGENPHQ AALY P G+A Sbjct 190 MYDVAVASWMTNVRAAASADSQFPRWMGATWERRSTLRYGENPHQSAALYTRPGEAEGIA 249 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSV----SVADAHR 302 QAEQLHGK+MSYNNFTD DAAWRAA+DHE CVAIIKHANPCGIA S + ++ADAHR Sbjct 250 QAEQLHGKEMSYNNFTDTDAAWRAAYDHEGPCVAIIKHANPCGIAESRLDGGAAIADAHR 309 Query 303 KAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLV 362 +AH CDP+SA+GGVIAAN E++VEMAE VS IFTEVIVAP Y GA++VL RKKNIR+L Sbjct 310 RAHACDPVSAFGGVIAANREITVEMAEQVSEIFTEVIVAPSYEEGAIEVLTRKKNIRILR 369 Query 363 AAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACR 422 +A P+ G+E+R ISGGLL+Q D L+A GDNP NWTLATG PAD TL DLVFAWRACR Sbjct 370 SAAPVRAGAEMRAISGGLLLQDRDVLNAGGDNPTNWTLATGDPADENTLRDLVFAWRACR 429 Query 423 AVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETL 482 AVKSNAI++A GATVGVGMGQVNRVDAARLAV R +R RG+VAASDAFFPFPDGL+ L Sbjct 430 AVKSNAILLADGGATVGVGMGQVNRVDAARLAVNRAADRARGSVAASDAFFPFPDGLQVL 489 Query 483 AAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AGV AVV PGGSVRD EV AA AGVTLYLTGARHFAH Sbjct 490 LDAGVRAVVQPGGSVRDNEVIAAAKDAGVTLYLTGARHFAH 530 >gi|229495107|ref|ZP_04388853.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodococcus erythropolis SK121] gi|229318038|gb|EEN83913.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Rhodococcus erythropolis SK121] Length=519 Score = 748 bits (1932), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/517 (72%), Positives = 422/517 (82%), Gaps = 1/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+ +RRAL+SVYDK+GL++LA GL AGVE++STGSTA IAD GIPVTPVE LTGFPE Sbjct 4 RKAVRRALVSVYDKSGLIELATGLHEAGVELVSTGSTASKIADAGIPVTPVEALTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 L+GRVKTLHPRVHAG+LAD RK +H A LE+LGI FELVVVNLYPF++TV SGAS D+C Sbjct 64 LEGRVKTLHPRVHAGVLADTRKPDHLAQLEELGIATFELVVVNLYPFTETVASGASPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y VL A+ GGFTL ER LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPARYADVLTAVAGGGFTLRERTVLAAQAFQHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM T+A + + FP W G +W R A+LRYGENPHQ AALY +P A GLA Sbjct 184 SYDVAVASWMTSTIAADEDGSLFPAWVGATWNRSAVLRYGENPHQDAALYENPAAPAGLA 243 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 QAEQLHGK+MSYNN+TD+DAAWRAA+D VAIIKHANPCGIAI + +ADAHRKAH Sbjct 244 QAEQLHGKEMSYNNYTDSDAAWRAAYDFTDPAVAIIKHANPCGIAIGT-DIADAHRKAHA 302 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDP+SA+GGVIAAN EV+VE+AE ++ IFTEV++AP Y GA++VL RKKNIRVL AA P Sbjct 303 CDPVSAFGGVIAANREVTVELAEQIADIFTEVVIAPSYEDGAVEVLQRKKNIRVLKAAAP 362 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 A G ELRPISGG L+QQ D LDA GDNPANWTLA G AD TL DL FAWRA R+VKS Sbjct 363 TATGIELRPISGGTLLQQRDVLDADGDNPANWTLANGEAADAETLADLEFAWRASRSVKS 422 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAI++A+ GA+VGVGMGQVNRVDAA LAV+R G+RV G+VAASDAFFPFPDGL+ L AG Sbjct 423 NAILLASGGASVGVGMGQVNRVDAAHLAVQRAGDRVVGSVAASDAFFPFPDGLQVLLNAG 482 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V AVV PGGSVRD EV AA +AGVTLYLTGARHFAH Sbjct 483 VKAVVQPGGSVRDNEVIAAAKEAGVTLYLTGARHFAH 519 >gi|226307910|ref|YP_002767870.1| bifunctional purine biosynthesis protein PurH [Rhodococcus erythropolis PR4] gi|226187027|dbj|BAH35131.1| bifunctional purine biosynthesis protein PurH [Rhodococcus erythropolis PR4] Length=519 Score = 747 bits (1929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/517 (72%), Positives = 422/517 (82%), Gaps = 1/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 R+ +RRAL+SVYDK+GL++LA GL AGVE++STGSTA IAD GIPVTPVE LTGFPE Sbjct 4 RKAVRRALVSVYDKSGLIELATGLHEAGVELVSTGSTASKIADAGIPVTPVEALTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 L+GRVKTLHPRVHAG+LAD RK +H A LE+LGI FELVVVNLYPF++TV SGAS D+C Sbjct 64 LEGRVKTLHPRVHAGVLADTRKPDHLAQLEELGIATFELVVVNLYPFTETVASGASPDEC 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y VL A+ GGFTL ER LA+ AFQH A Sbjct 124 VEQIDIGGPSMVRAAAKNHPSVAVVVDPARYADVLTAVAGGGFTLRERTVLAAQAFQHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM T+A + + FP W G +W R A+LRYGENPHQ AALY +P A GLA Sbjct 184 SYDVAVASWMTGTIAADEDGSLFPAWVGATWNRSAVLRYGENPHQDAALYENPAAPAGLA 243 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 QAEQLHGK+MSYNN+TD+DAAWRAA+D VAIIKHANPCGIAI + +ADAHRKAH Sbjct 244 QAEQLHGKEMSYNNYTDSDAAWRAAYDFTDPAVAIIKHANPCGIAIGT-DIADAHRKAHA 302 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDP+SA+GGVIAAN EV+VE+AE ++ IFTEV++AP Y GA++VL RKKNIRVL AA P Sbjct 303 CDPVSAFGGVIAANREVTVELAEQIADIFTEVVIAPSYEDGAVEVLQRKKNIRVLKAAAP 362 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 A G ELRPISGG L+QQ D LDA GDNPANWTLA G AD TL DL FAWRA R+VKS Sbjct 363 TATGIELRPISGGTLLQQRDVLDADGDNPANWTLANGEAADAETLADLEFAWRASRSVKS 422 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAI++A+ GA+VGVGMGQVNRVDAA LAV+R G+RV G+VAASDAFFPFPDGL+ L AG Sbjct 423 NAILLASGGASVGVGMGQVNRVDAAHLAVQRAGDRVVGSVAASDAFFPFPDGLQVLLNAG 482 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V AVV PGGSVRD EV AA +AGVTLYLTGARHFAH Sbjct 483 VKAVVQPGGSVRDNEVIAAAKEAGVTLYLTGARHFAH 519 >gi|343927178|ref|ZP_08766657.1| bifunctional purine biosynthesis protein PurH [Gordonia alkanivorans NBRC 16433] gi|343762916|dbj|GAA13583.1| bifunctional purine biosynthesis protein PurH [Gordonia alkanivorans NBRC 16433] Length=524 Score = 746 bits (1927), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/520 (71%), Positives = 422/520 (82%), Gaps = 2/520 (0%) Query 4 DDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGF 63 D RRPIRRAL+SVYDK+GL DLA L AAGVEI+STGSTAKTIAD G+PV V LTGF Sbjct 7 DSARRPIRRALVSVYDKSGLADLATALQAAGVEIVSTGSTAKTIADAGVPVVEVSALTGF 66 Query 64 PEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASV 123 PE LDGRVKTLHP+VHAG+LAD RK +H A L +LG+ AF+LVVVNLYPF+ TV SGA+ Sbjct 67 PECLDGRVKTLHPKVHAGILADTRKDDHVAQLAELGVAAFDLVVVNLYPFTATVASGATP 126 Query 124 DDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQ 183 D+C+EQIDIGGP+MVR AAKNHPS AVVT P Y V A+ AGGFTLA+RK+LA+ AF+ Sbjct 127 DECIEQIDIGGPSMVRGAAKNHPSVAVVTSPGDYGHVTEAISAGGFTLADRKKLAAKAFR 186 Query 184 HIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWP 243 H A+YD+AVASWM +APE + FP W G +W R A+LRYGENPHQ AALY Sbjct 187 HTADYDVAVASWMSSVVAPEDD-SQFPIWAGATWNRSAVLRYGENPHQAAALYVGNAGEG 245 Query 244 GLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRK 303 GLA AEQLHGK+MSYNN+TDADAAWRAA+D E VAIIKHANPCGIA+ + +A+AHRK Sbjct 246 GLATAEQLHGKEMSYNNYTDADAAWRAAYDFEAPAVAIIKHANPCGIAVGA-DIAEAHRK 304 Query 304 AHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVA 363 AH CDP+SAYGGVIAAN E++VEMAE V+ IFTEV+VAPG+A GAL VL RKKNIRVLVA Sbjct 305 AHACDPVSAYGGVIAANREITVEMAEQVAEIFTEVVVAPGFADGALSVLTRKKNIRVLVA 364 Query 364 AEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRA 423 P A G E +P+SGGLLIQQ D +DA GDNP NW L G PAD TL DL FAWRACR+ Sbjct 365 TPPSATGVETKPVSGGLLIQQRDVIDAEGDNPDNWNLVAGPPADAQTLADLEFAWRACRS 424 Query 424 VKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLA 483 VKSNAI++A+DGA+VGVGMGQVNRVD+A LAV+R G+R G+V ASDAFFPFPDGL+ L Sbjct 425 VKSNAILLASDGASVGVGMGQVNRVDSAHLAVQRAGDRAAGSVGASDAFFPFPDGLQVLL 484 Query 484 AAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 +AGV AVV PGGS+RD EV EAA +AGVTLYLTGARHFAH Sbjct 485 SAGVKAVVQPGGSIRDNEVIEAADEAGVTLYLTGARHFAH 524 >gi|312138589|ref|YP_004005925.1| phosphoribosylphosphoimidazolecarboxamide formyltransferase/imp cyclohydrolase purhj [Rhodococcus equi 103S] gi|311887928|emb|CBH47240.1| phosphoribosylphosphoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurHJ [Rhodococcus equi 103S] Length=522 Score = 746 bits (1926), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/523 (71%), Positives = 426/523 (82%), Gaps = 10/523 (1%) Query 10 IRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDG 69 +RRAL+SVYDKTGLV+LA GL AGVE++STGSTA IA+ GIPVT VE LTGFPE L+G Sbjct 1 MRRALVSVYDKTGLVELATGLHQAGVELVSTGSTAAKIAEAGIPVTKVEDLTGFPECLEG 60 Query 70 RVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQ 129 RVKTLHPRVHAG+LAD RK EH A LE+LGIEAF+LV+VNLYPF+QTV SGA+ D+CVEQ Sbjct 61 RVKTLHPRVHAGVLADTRKPEHLAQLEELGIEAFQLVIVNLYPFTQTVASGATPDECVEQ 120 Query 130 IDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYD 189 IDIGGP+MVRAAAKNHPS AVV DP Y GVLAA+ AGGF L ER LA+ AFQH A YD Sbjct 121 IDIGGPSMVRAAAKNHPSVAVVVDPAKYEGVLAAVEAGGFNLFERTALAAQAFQHTASYD 180 Query 190 IAVASWMQQTL----AP-----EHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 +AVA+WM ++L AP + ++ FP+W G +W R A+LRYGENPHQ AALY P Sbjct 181 VAVATWMTESLVETVAPSEETDDSALSKFPRWVGATWNRSAVLRYGENPHQAAALYDSPA 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 GLAQA+Q HGK+MSYNN+TD DAAWRAA+DH + VAIIKHANPCGIA+ + +A+A Sbjct 241 GPAGLAQAKQFHGKEMSYNNYTDGDAAWRAAYDHAEPAVAIIKHANPCGIAVGA-DIAEA 299 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAH CDP+SA+GGVIAAN EV+VEMAE V+ IFTEV++AP YAPGA++VLARKKN+RV Sbjct 300 HRKAHACDPVSAFGGVIAANREVTVEMAEQVADIFTEVVIAPSYAPGAVEVLARKKNVRV 359 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 L AA P G ELRPISGG L+Q D LDA GD+ ANWTL G AD TL DL FAWRA Sbjct 360 LEAAAPTETGIELRPISGGALLQDRDVLDADGDDSANWTLVVGDAADEKTLADLEFAWRA 419 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE 480 CRAVKSNAI++A DGA+VGVGMGQVNRVD+A LAV+R G+R +G+VAASDAFFPFPDGL+ Sbjct 420 CRAVKSNAILLANDGASVGVGMGQVNRVDSAHLAVQRAGDRAKGSVAASDAFFPFPDGLQ 479 Query 481 TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 L AGV AVV PGGSVRD EV EAA +AGVTLYLTGARHFAH Sbjct 480 VLLDAGVRAVVQPGGSVRDNEVIEAAREAGVTLYLTGARHFAH 522 >gi|326383724|ref|ZP_08205409.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Gordonia neofelifaecis NRRL B-59395] gi|326197488|gb|EGD54677.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Gordonia neofelifaecis NRRL B-59395] Length=524 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/520 (71%), Positives = 426/520 (82%), Gaps = 1/520 (0%) Query 4 DDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGF 63 D G R ++RALISVYDK+GL DLA L+AAGVEI+STGSTAKTIA G+PV V +LTGF Sbjct 6 DSGTRAVKRALISVYDKSGLTDLATALNAAGVEIVSTGSTAKTIAGAGVPVIEVSELTGF 65 Query 64 PEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASV 123 PE L+GRVKTLHPRVHAG+LAD RK +H A L++LG+ FELVVVNLYPF++TV SGA+ Sbjct 66 PECLEGRVKTLHPRVHAGILADTRKDDHLAQLDELGVAPFELVVVNLYPFTETVASGATP 125 Query 124 DDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQ 183 D+CVEQIDIGGP+MVRAAAKNHPS VV DP Y V AA+ GGFTLA+RK+LA+ AF+ Sbjct 126 DECVEQIDIGGPSMVRAAAKNHPSVGVVVDPADYADVAAAVATGGFTLAQRKQLAAKAFR 185 Query 184 HIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWP 243 H A+YD+AVASWM +AP+ + FP W G +W+R A LRYGENPHQ AALY A P Sbjct 186 HTADYDVAVASWMSSVVAPDEEGSQFPVWAGATWKRSATLRYGENPHQAAALYVSNDAAP 245 Query 244 GLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRK 303 GLA+A+QLHGK+MS+NN+TD DAAWRAA+DH + VAIIKHANPCGIA+ + +A+AHR+ Sbjct 246 GLAEAQQLHGKEMSFNNYTDGDAAWRAAYDHAEPAVAIIKHANPCGIAVGA-DIAEAHRR 304 Query 304 AHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVA 363 AH CDP+SAYGGVIA N EVSVEMAE V+ IFTEVI+APGYA GA+DVL+RKKNIR+L+A Sbjct 305 AHACDPVSAYGGVIATNREVSVEMAEQVAEIFTEVIIAPGYADGAVDVLSRKKNIRILIA 364 Query 364 AEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRA 423 P G E+RP+SGGLLIQ+ D +DA GD+PANWTLATG AD TL DLVFAWRACRA Sbjct 365 GAPTETGVEMRPVSGGLLIQERDVIDADGDDPANWTLATGEAADEQTLRDLVFAWRACRA 424 Query 424 VKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLA 483 VKSNAI++A DGA+VGVGMGQVNRVD+A LAV R GER G+V ASDAFFPFPDGL+ L Sbjct 425 VKSNAILLANDGASVGVGMGQVNRVDSAHLAVNRAGERAAGSVGASDAFFPFPDGLQVLI 484 Query 484 AAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 GV AVV PGGSVRD EV EAA AGVT+YLTGARHFAH Sbjct 485 DGGVRAVVQPGGSVRDNEVIEAAKAAGVTMYLTGARHFAH 524 >gi|262201336|ref|YP_003272544.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Gordonia bronchialis DSM 43247] gi|262084683|gb|ACY20651.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Gordonia bronchialis DSM 43247] Length=530 Score = 723 bits (1866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/519 (71%), Positives = 424/519 (82%), Gaps = 5/519 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 RRPIRRAL+SVYDKTGLVDLA L AAGVE++STGSTAKTIA G+PV V ++TGFPE Sbjct 15 RRPIRRALVSVYDKTGLVDLATALHAAGVELVSTGSTAKTIAGAGVPVVEVSEVTGFPEC 74 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHP VHAG+LAD RK H A L++LGI AF+L+V NLYPF++TV SGA D+C Sbjct 75 LDGRVKTLHPNVHAGMLADTRKDSHVAQLDELGIAAFDLMVGNLYPFTETVASGAGPDEC 134 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 +EQIDIGGPAMVR+AAKNHPS AVV DP+ Y + A+ AGGFTLA+R+ LA+ AF+H+A Sbjct 135 IEQIDIGGPAMVRSAAKNHPSVAVVVDPVDYAALTDAVGAGGFTLAQRQALAAKAFRHVA 194 Query 187 EYDIAVASWMQQTLAP--EHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 +YD+AVA WM +AP EHP FP+W G +W R A+LRYGENPHQ AALY D + G Sbjct 195 DYDVAVAEWMSTVVAPAAEHP--EFPEWTGATWTRSAVLRYGENPHQAAALYLDNASGGG 252 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LA AEQLHGK+MSYNN+TD+DAAWR+A D + VAIIKHANPCGIA+ + +A+AHRKA Sbjct 253 LANAEQLHGKEMSYNNYTDSDAAWRSAHDFDAPAVAIIKHANPCGIAVGA-DIAEAHRKA 311 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDP+SAYGGVIAAN E++VEMAE V+ IFTEVI+APG+A GAL VL RKKNIRVLVA Sbjct 312 HACDPVSAYGGVIAANREITVEMAEQVAEIFTEVIIAPGFADGALSVLTRKKNIRVLVAT 371 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 P GG E +P+SGGLL+QQ D LDA GDNPANWTLA G AD ATL DL FAWRACR+V Sbjct 372 PPTGGGLETKPVSGGLLVQQRDVLDADGDNPANWTLAAGEAADAATLADLEFAWRACRSV 431 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAA 484 KSNAI++A+DGA+VGVGMGQVNRVD+A LAV R G+R G+V ASDAFFPFPDGL+ L Sbjct 432 KSNAILLASDGASVGVGMGQVNRVDSAHLAVTRAGDRAAGSVGASDAFFPFPDGLQVLLT 491 Query 485 AGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AGV AVV PGGS+RD EV AAA AGVTLYLTGARHFAH Sbjct 492 AGVKAVVQPGGSIRDNEVIAAAADAGVTLYLTGARHFAH 530 >gi|302205786|gb|ADL10128.1| Bifunctional purine biosynthesis protein purH [Corynebacterium pseudotuberculosis C231] gi|308276021|gb|ADO25920.1| IMP cyclohydrolase [Corynebacterium pseudotuberculosis I19] gi|341824459|gb|AEK91980.1| Bifunctional purine biosynthesis protein purH [Corynebacterium pseudotuberculosis PAT10] Length=525 Score = 721 bits (1860), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/525 (68%), Positives = 416/525 (80%), Gaps = 8/525 (1%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL +LA L+ AGVEI+STGSTA TIA GIPVTPVE LTGFP Sbjct 3 DDRKQIKRALISVYDKTGLEELAHALNQAGVEIVSTGSTAATIAKQGIPVTPVEALTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP+VHAG+LAD RK++H A L++LG+ F+LVVVNLYPF+QTV SGA D Sbjct 63 ECLEGRVKTLHPKVHAGILADTRKADHLAQLDELGVSLFQLVVVNLYPFTQTVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y V A++AGGFT AER LA AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPERYTAVAEAIQAGGFTRAERTELAVDAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 A YD+AVA+WM + +A + + W G S+ R ++LRYGENPHQ AALY DP A G Sbjct 183 TASYDVAVATWMGEQIAGD--AEEYAPWIGASYARTSVLRYGENPHQSAALYVDPNAPAG 240 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQAEQLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A+AHR A Sbjct 241 LAQAEQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDASIAEAHRLA 300 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDP+SA+GGVIA+N EVSVEMA+ VS IFTEVI+AP Y GA+++L++KKNIR+LVA Sbjct 301 HACDPVSAFGGVIASNREVSVEMAQQVSEIFTEVIIAPSYEEGAVELLSQKKNIRILVAP 360 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 P+ E R ISGGLL+Q+ D +DA GD P NWTL G A P L DL FAWR RAV Sbjct 361 APVRDQKEQRQISGGLLVQRRDLVDAEGDAPENWTLVAGEAATPELLADLEFAWRTVRAV 420 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDAFFPFPDG 478 KSNAI++A DGATVGVGMGQVNRVDAA+LAVER +R +GAVAASDAFFPF DG Sbjct 421 KSNAILLAQDGATVGVGMGQVNRVDAAKLAVERANSLAGEQQRAKGAVAASDAFFPFADG 480 Query 479 LETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E LA AGV AVV PGGS+RD EV +AA KAGVT+YLTGARHFAH Sbjct 481 FEVLAHAGVKAVVQPGGSIRDAEVIQAAEKAGVTMYLTGARHFAH 525 >gi|300858064|ref|YP_003783047.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium pseudotuberculosis FRC41] gi|300685518|gb|ADK28440.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium pseudotuberculosis FRC41] gi|302330345|gb|ADL20539.1| Bifunctional purine biosynthesis protein purH [Corynebacterium pseudotuberculosis 1002] Length=525 Score = 720 bits (1859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/525 (68%), Positives = 416/525 (80%), Gaps = 8/525 (1%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL +LA L+ AGVEI+STGSTA TIA GIPVTPVE LTGFP Sbjct 3 DDRKQIKRALISVYDKTGLEELAHALNQAGVEIVSTGSTAATIAKQGIPVTPVEALTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP+VHAG+LAD RK++H A L++LG+ F+LVVVNLYPF+QTV SGA D Sbjct 63 ECLEGRVKTLHPKVHAGILADTRKADHLAQLDELGVSLFQLVVVNLYPFTQTVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y V A++AGGFT AER LA AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPERYTAVAEAIQAGGFTRAERTELAVDAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 A YD+AVA+WM + +A + + W G S+ R ++LRYGENPHQ AALY DP A G Sbjct 183 TASYDVAVATWMGEQIAGD--AEEYAPWIGASYARTSVLRYGENPHQSAALYVDPNAPAG 240 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQAEQLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A+AHR A Sbjct 241 LAQAEQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDASIAEAHRLA 300 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDP+SA+GGVIA+N EVSVEMA+ VS IFTEVI+AP Y GA+++L++KKNIR+LVA Sbjct 301 HACDPVSAFGGVIASNREVSVEMAQQVSEIFTEVIIAPSYEEGAVELLSQKKNIRILVAP 360 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 P+ E R ISGGLL+Q+ D +DA GD P NWTL G A P L DL FAWR RAV Sbjct 361 APVRDQKEQRQISGGLLVQRRDLVDAEGDAPENWTLVAGEAATPELLADLEFAWRTVRAV 420 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDAFFPFPDG 478 KSNAI++A DGATVGVGMGQVNRVDAA+LAVER +R +GAVAASDAFFPF DG Sbjct 421 KSNAILLAQDGATVGVGMGQVNRVDAAKLAVERADSLAGEQQRAKGAVAASDAFFPFADG 480 Query 479 LETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E LA AGV AVV PGGS+RD EV +AA KAGVT+YLTGARHFAH Sbjct 481 FEVLAHAGVKAVVQPGGSIRDAEVIQAAEKAGVTMYLTGARHFAH 525 >gi|334696428|gb|AEG81225.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium ulcerans 809] Length=525 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/525 (68%), Positives = 413/525 (79%), Gaps = 8/525 (1%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL +LA L+ AGVEI+STGSTA TIA GIPVTPVE+LTGFP Sbjct 3 DDRKQIKRALISVYDKTGLEELAHALNQAGVEIVSTGSTAATIAKQGIPVTPVEKLTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP++HAG+LAD RK +H A L++LG+ F+LVVVNLYPF+QTV SGA D Sbjct 63 ECLEGRVKTLHPKIHAGILADTRKEDHLAQLDELGVSLFQLVVVNLYPFTQTVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y V A+RAGGFT AER LA AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPERYAAVAEAIRAGGFTRAERTELAVDAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 A YD+AVA+WM + +A + + W G S+ R +LRYGENPHQ AALY DP A G Sbjct 183 TASYDVAVATWMGEQIADDSE--EYAPWIGASYSRANVLRYGENPHQSAALYVDPNAPAG 240 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQAEQLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A+AHR A Sbjct 241 LAQAEQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDASIAEAHRLA 300 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDP+SA+GGVIA+N EVSV+MA+ VS IFTEVI+AP Y GA+++L++KKNIR+LVA Sbjct 301 HACDPVSAFGGVIASNREVSVDMAQQVSEIFTEVIIAPAYEDGAVEILSQKKNIRILVAP 360 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 EP E R ISGGLL+Q+ D +DA GD P WTL G P L DL FAWR RAV Sbjct 361 EPPQEKVEQRQISGGLLVQRRDLVDAEGDAPEKWTLVAGEAVSPELLADLEFAWRTVRAV 420 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDAFFPFPDG 478 KSNAI++A DGATVGVGMGQVNRVDAA+LAVER +R +GAVAASDAFFPF DG Sbjct 421 KSNAILLAQDGATVGVGMGQVNRVDAAKLAVERANSLAGEQQRAQGAVAASDAFFPFADG 480 Query 479 LETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E LA AGV AVV PGGS+RD EV +AA KAGVT+Y+TGARHFAH Sbjct 481 FEVLARAGVKAVVQPGGSIRDAEVIQAAEKAGVTMYVTGARHFAH 525 >gi|169628159|ref|YP_001701808.1| bifunctional phospho ribosylaminoimidazole carboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium abscessus ATCC 19977] gi|169240126|emb|CAM61154.1| Probable bifunctional purine biosynthesis protein PurH [Mycobacterium abscessus] Length=526 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/517 (74%), Positives = 429/517 (83%), Gaps = 3/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 +RP+RRALISVYDKTGL +LA GL AAGVE++STGSTAKTIA IPVTPVE +TGFPEV Sbjct 13 QRPVRRALISVYDKTGLEELASGLHAAGVELVSTGSTAKTIAAASIPVTPVEDVTGFPEV 72 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHP VHAG+LAD R+ EH LE+LG++ FELVVVNLYPF+ TV SGAS D+C Sbjct 73 LDGRVKTLHPHVHAGVLADTRREEHLTQLEELGVQGFELVVVNLYPFAATVASGASEDEC 132 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVV DP Y VLAA+ AGGFTL RK LA+ AF+H A Sbjct 133 VEQIDIGGPSMVRAAAKNHPSVAVVVDPAAYGEVLAAVTAGGFTLEARKVLAAKAFRHTA 192 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 EYD+AVA W+ P A P W G +W R A+LRYGENPHQQAALY A GLA Sbjct 193 EYDVAVAGWLSGVAEPGD--AELPSWIGGTWNRSAVLRYGENPHQQAALY-IGAAGQGLA 249 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 QAEQLHGK+MSYNN+TDADAAWRAA+D ++ C AIIKHANPCGIA+S +S+ADAH KAHE Sbjct 250 QAEQLHGKEMSYNNYTDADAAWRAAWDQDKACAAIIKHANPCGIAVSDISIADAHLKAHE 309 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDPLSA+GGVIA N EVSVEMAE V+ IFTEVIVAPGYA GA++VL+RKKN+R+L AA+P Sbjct 310 CDPLSAFGGVIAVNREVSVEMAERVADIFTEVIVAPGYADGAVEVLSRKKNVRLLRAAQP 369 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 +G +E R ISGGLL+Q+ D LDA GD+PANWTL G+ AD TL DLVFAW+ RAVKS Sbjct 370 ESGSTEWRQISGGLLVQERDALDAEGDDPANWTLVAGAAADADTLADLVFAWKVGRAVKS 429 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAIVIA+ GAT+GVGMGQVNRVDAARLAV RGG+RV GAVAASDAFFPFPDGLE L+ AG Sbjct 430 NAIVIASGGATIGVGMGQVNRVDAARLAVSRGGDRVSGAVAASDAFFPFPDGLEVLSQAG 489 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V AVVHPGGS+RDE VT+AA AG+TLY TGARHFAH Sbjct 490 VRAVVHPGGSMRDELVTDAAKAAGITLYTTGARHFAH 526 >gi|337290312|ref|YP_004629333.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium ulcerans BR-AD22] gi|334698618|gb|AEG83414.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium ulcerans BR-AD22] Length=525 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/525 (68%), Positives = 413/525 (79%), Gaps = 8/525 (1%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL +LA L+ AGVEI+STGSTA IA GIPVTPVE+LTGFP Sbjct 3 DDRKQIKRALISVYDKTGLEELAHALNQAGVEIVSTGSTAAAIAKQGIPVTPVEKLTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP++HAG+LAD RK +H A L++LG+ F+LVVVNLYPF+QTV SGA D Sbjct 63 ECLEGRVKTLHPKIHAGILADTRKEDHLAQLDELGVSLFQLVVVNLYPFTQTVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y V A+RAGGFT AER LA AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPERYAAVAEAIRAGGFTRAERTELAVEAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 A YD+AVA+WM + +A + + W G S+ R +LRYGENPHQ AALY DP A G Sbjct 183 TASYDVAVATWMGEQIADDSE--EYAPWIGASYSRANVLRYGENPHQSAALYVDPNAPAG 240 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQAEQLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A+AHR A Sbjct 241 LAQAEQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDASIAEAHRLA 300 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDP+SA+GGVIA+N EVSV+MA+ VS IFTEVI+AP Y GA+++L++KKNIR+LVA Sbjct 301 HACDPVSAFGGVIASNREVSVDMAQQVSEIFTEVIIAPAYEDGAVEILSQKKNIRILVAP 360 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 EP E R ISGGLL+Q+ D +DA GD P WTL G A P L DL FAWR RAV Sbjct 361 EPPQEKIEQRQISGGLLVQRRDLVDAEGDAPEKWTLVAGEAASPELLADLEFAWRTVRAV 420 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDAFFPFPDG 478 KSNAI++A DGATVGVGMGQVNRVDAA+LAVER +R +GAVAASDAFFPF DG Sbjct 421 KSNAILLAQDGATVGVGMGQVNRVDAAKLAVERANSLAGEQQRAQGAVAASDAFFPFADG 480 Query 479 LETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E LA AGV AVV PGGS+RD EV +AA KAGVT+Y+TGARHFAH Sbjct 481 FEVLARAGVKAVVQPGGSIRDAEVIQAAEKAGVTMYVTGARHFAH 525 >gi|29829987|ref|NP_824621.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces avermitilis MA-4680] gi|29607097|dbj|BAC71156.1| putative bifunctional purine biosynthesis protein [Streptomyces avermitilis MA-4680] Length=527 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/518 (71%), Positives = 414/518 (80%), Gaps = 4/518 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 +RPIRRALISVYDKTGL DLA+GL AGVE++STGSTA IA G+PVT VE+LTGFPE Sbjct 13 QRPIRRALISVYDKTGLEDLARGLHEAGVELVSTGSTAAKIAAAGVPVTKVEELTGFPEC 72 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHP+VHAG+LADLR EH LE+LG+E F+LVVVNLYPF +TV SGAS D+C Sbjct 73 LDGRVKTLHPKVHAGILADLRLDEHRRQLEELGVEPFQLVVVNLYPFRETVASGASPDEC 132 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVVT P Y VL+A+R GGF L RKRLA+ AF+H A Sbjct 133 VEQIDIGGPSMVRAAAKNHPSVAVVTSPERYADVLSAVRGGGFDLTARKRLAAEAFRHTA 192 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASW + AP + FP + G ++ R + LRYGENPHQ AALY D GLA Sbjct 193 AYDVAVASWFASSYAPVDE-SVFPDFLGATFERKSTLRYGENPHQPAALYVD-GGGTGLA 250 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 +AEQLHGK+MSYNN+TD DAA RAA+DH + CVAIIKHANPCGIAI + VA+AHRKAH Sbjct 251 EAEQLHGKEMSYNNYTDTDAARRAAYDHAEPCVAIIKHANPCGIAIGA-DVAEAHRKAHA 309 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDPLSA+GGVIA N VS E+AE V+ IFTEVIVAPGY GAL+ LA+KKNIRVL A + Sbjct 310 CDPLSAFGGVIAVNRPVSKELAEQVAEIFTEVIVAPGYEDGALEALAKKKNIRVLRAQDA 369 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 A +EL+ I GG L+Q +D+L A GD+PANWTLATG PA L +L FAWRACRAVKS Sbjct 370 PANPAELKQIDGGALLQVTDRLQADGDDPANWTLATGEALSPAELDELAFAWRACRAVKS 429 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGG-ERVRGAVAASDAFFPFPDGLETLAAA 485 NAI++A DGA+VGVGMGQVNRVD+A+LAVER G ER RGA AASDAFFPFPDGLE L AA Sbjct 430 NAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGAFAASDAFFPFPDGLEILTAA 489 Query 486 GVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 GV AVV PGGSVRDE V EAA KAGVT+Y TG RHF H Sbjct 490 GVRAVVQPGGSVRDELVVEAAKKAGVTMYFTGTRHFFH 527 >gi|38233436|ref|NP_939203.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium diphtheriae NCTC 13129] gi|81401661|sp|Q6NID8.1|PUR9_CORDI RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|38199696|emb|CAE49355.1| bifunctional purine biosynthesis protein [Corynebacterium diphtheriae] Length=525 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/526 (68%), Positives = 416/526 (80%), Gaps = 10/526 (1%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL DLA+ L+ AGVEI+STGSTA IAD G+PVTPVEQLTGFP Sbjct 3 DDRKQIKRALISVYDKTGLEDLARALNDAGVEIVSTGSTAAKIADLGVPVTPVEQLTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP VHAG+LAD RK +H L++L + F+LVVVNLYPF+QTV SGA D Sbjct 63 ECLEGRVKTLHPMVHAGILADTRKEDHLKQLDELNVAPFQLVVVNLYPFTQTVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y ++AA+ GGFT AER LA AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPSRYSEIIAAVGNGGFTRAERTALAVDAFRH 182 Query 185 IAEYDIAVASWMQQTLAP-EHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWP 243 A YD+AVA+WM + +A + P F +W G S+ R +LRYGENPHQ AALY DP A Sbjct 183 TASYDVAVATWMGEQIADADKP---FAEWIGASYERANILRYGENPHQAAALYTDPAAPA 239 Query 244 GLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRK 303 GLAQA QLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S VS+A+AHR Sbjct 240 GLAQATQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDVSIAEAHRT 299 Query 304 AHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVA 363 AH CDP+SA+GGVIA+N EVSV+MA+ VS IFTEVI+AP Y GA+D+L++KKNIR+LVA Sbjct 300 AHACDPVSAFGGVIASNREVSVDMAKQVSEIFTEVIIAPSYEDGAVDILSQKKNIRILVA 359 Query 364 AEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRA 423 +P E R ISGG+L+Q+ D +DA GD PANWTLA G A L +L FAWRA RA Sbjct 360 PQPQRDELEQRQISGGVLVQRRDLVDAEGDTPANWTLAAGEGASEELLAELEFAWRAVRA 419 Query 424 VKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDAFFPFPD 477 VKSNAI++A GATVGVGMGQVNRVDAA+LAVER +R +G+VAASDAFFPF D Sbjct 420 VKSNAILLAQGGATVGVGMGQVNRVDAAKLAVERANSLAGDEQRAKGSVAASDAFFPFAD 479 Query 478 GLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 G E LA AGV AVV PGGS+RD EV EAA KAGVT+YLTGARHFAH Sbjct 480 GFEVLAQAGVRAVVQPGGSIRDAEVIEAANKAGVTMYLTGARHFAH 525 >gi|134103094|ref|YP_001108755.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Saccharopolyspora erythraea NRRL 2338] gi|291003963|ref|ZP_06561936.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Saccharopolyspora erythraea NRRL 2338] gi|133915717|emb|CAM05830.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Saccharopolyspora erythraea NRRL 2338] Length=521 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/517 (70%), Positives = 411/517 (80%), Gaps = 3/517 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 RRP+RRALI V DK+GL++LA GL AAGVEI+STG TAKTIA G+PVTPVE+LTGFPE Sbjct 8 RRPVRRALIGVSDKSGLLELATGLHAAGVEIVSTGGTAKTIAAAGVPVTPVEELTGFPEA 67 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHPRVHAGLLADLRK EHA L LGI F+L+VVNLYPF QTV SGA D+ Sbjct 68 LDGRVKTLHPRVHAGLLADLRKQEHADQLADLGIAPFDLLVVNLYPFVQTVASGADQDEV 127 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 +EQIDIGGPAMVRA+AKNH + AVV DP Y VL +R GGF+LA+R LA+ AF+H A Sbjct 128 IEQIDIGGPAMVRASAKNHANVAVVVDPNRYEWVLEQVREGGFSLADRVELAAAAFRHTA 187 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD+AVASWM +T A + V FP W G +W R + LRYGENPHQ AALY GLA Sbjct 188 SYDVAVASWMSRTPAGDDSV--FPGWIGETWERRSALRYGENPHQPAALYVSGGEATGLA 245 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHE 306 A QLHGK+MSYNN+ DADAAWRAA DH CVAIIKHANPCGIA++ +ADAHRKAHE Sbjct 246 AAAQLHGKEMSYNNYVDADAAWRAAHDHADPCVAIIKHANPCGIAVAG-DIADAHRKAHE 304 Query 307 CDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEP 366 CDP+SAYGGVIA N EVSV++AE +S IFTEV+VAPGYA GA+DVL+RKKN+R+L A P Sbjct 305 CDPVSAYGGVIATNREVSVKLAEQISEIFTEVVVAPGYAEGAVDVLSRKKNVRILTAQPP 364 Query 367 LAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKS 426 +G E+R ISGG+L+Q SD +DA GD+PA W L GS D ATL+DL FAWRACRAVKS Sbjct 365 KSGRVEMRAISGGMLVQGSDAVDAEGDDPAAWRLVAGSAVDEATLSDLKFAWRACRAVKS 424 Query 427 NAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAG 486 NAI++AADGATVGVGMGQVNRVD+ARL+V R G+R +G+VAASDAFFPFPDG E L AG Sbjct 425 NAILLAADGATVGVGMGQVNRVDSARLSVARAGDRAKGSVAASDAFFPFPDGAEVLMEAG 484 Query 487 VTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 V A+V PGGSVRDE V AA AGV +Y TG RHFAH Sbjct 485 VRAIVQPGGSVRDESVIAAAEAAGVAMYFTGTRHFAH 521 >gi|336326232|ref|YP_004606198.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium resistens DSM 45100] gi|336102214|gb|AEI10034.1| phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [Corynebacterium resistens DSM 45100] Length=529 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/532 (69%), Positives = 418/532 (79%), Gaps = 15/532 (2%) Query 3 TDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTG 62 T+D ++ IRRALISVYDKTGL +LA+GL AGV I+STGSTAK IAD G+PVT VEQLTG Sbjct 2 TED-KKAIRRALISVYDKTGLEELAKGLHDAGVSIVSTGSTAKKIADAGVPVTEVEQLTG 60 Query 63 FPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGAS 122 FPEVL+GRVKTLHPRVHAG+LAD RKS+H LE L +EAFELVVVNLYPFS TV SGA Sbjct 61 FPEVLEGRVKTLHPRVHAGILADTRKSDHLQQLEDLDVEAFELVVVNLYPFSDTVASGAD 120 Query 123 VDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAF 182 D CVEQIDIGGP+MVRAAAKNHPS AVV DP Y V+ A R GGF+ AER +LA AF Sbjct 121 FDACVEQIDIGGPSMVRAAAKNHPSVAVVVDPARYGDVIVAAREGGFSRAERTKLALAAF 180 Query 183 QHIAEYDIAVASWMQQTLAPE--HPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 +H A YD+AVASW+ + + E + FP+W G ++ R +LRYGENPHQ AALY + Sbjct 181 RHTAAYDVAVASWLGEHVDSEGAEGDSQFPEWIGETYERANVLRYGENPHQAAALYSNGG 240 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 GLA A+Q HGK+MSYNN+TD+DAAWRAA+DHE+ VAIIKHANPCGIA+S S+A A Sbjct 241 ---GLAGAKQFHGKEMSYNNYTDSDAAWRAAWDHERPAVAIIKHANPCGIAVSDESIATA 297 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HR+AH CDP+SA+GGVIAAN EV+VEMA+ V+ IFTEVI+AP Y GA++VL++KKNIR+ Sbjct 298 HRQAHACDPMSAFGGVIAANREVTVEMAKQVAEIFTEVIIAPSYEDGAVEVLSQKKNIRI 357 Query 361 LVAAEPL---AGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFA 417 L A P E R ISGG+L+QQ D +DA GD+PANWTLA G AD TL +LVFA Sbjct 358 LQAEAPKPDERAAVEHRQISGGVLVQQRDIIDAKGDDPANWTLAAGEAADEKTLAELVFA 417 Query 418 WRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG------ERVRGAVAASDA 471 WR+ RAVKSNAI++A DGATVGVGMGQVNRVDAA+LAVER ER RGAVAASDA Sbjct 418 WRSVRAVKSNAILLAKDGATVGVGMGQVNRVDAAKLAVERANSLAGDEERARGAVAASDA 477 Query 472 FFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 FFPF DG E LA AGV AVV PGGSVRD EV EAA KAGVT+YLTG RHFAH Sbjct 478 FFPFADGFEVLANAGVRAVVQPGGSVRDAEVIEAANKAGVTMYLTGERHFAH 529 >gi|25027493|ref|NP_737547.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium efficiens YS-314] gi|259507100|ref|ZP_05750000.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium efficiens YS-314] gi|29336730|sp|Q8FR29.1|PUR9_COREF RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|23492775|dbj|BAC17747.1| phosphoribosylaminoimidazolecarboxamideformyltra nsferase/IMP cyclohydrolase [Corynebacterium efficiens YS-314] gi|259165378|gb|EEW49932.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium efficiens YS-314] Length=521 Score = 711 bits (1836), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/524 (68%), Positives = 413/524 (79%), Gaps = 4/524 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 MS D R+ I+RALISVYDKTGL DLAQ L AGVEI+STGSTA IAD GIPVTPVE+L Sbjct 1 MSED--RKAIKRALISVYDKTGLEDLAQALHRAGVEIVSTGSTAAKIADLGIPVTPVEEL 58 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPE L+GRVKTLHP+VHAG+LAD RK +H L++LG+ F+LVVVNLYPF++TV SG Sbjct 59 TGFPECLEGRVKTLHPKVHAGILADTRKDDHLRQLDELGVTPFQLVVVNLYPFAETVASG 118 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 A DDCVEQIDIGGP+MVRAAAKNHPS AVVT P Y V++ L GGF+ AER +LA+ Sbjct 119 ADFDDCVEQIDIGGPSMVRAAAKNHPSVAVVTSPGQYEDVVSVLNTGGFSRAERTKLAAE 178 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AF+H A YD+ VA+W+ + L+ FP W G + LRYGENPHQ AALY Sbjct 179 AFRHTATYDVTVATWISEQLSAADTELEFPGWIGSTSTLARSLRYGENPHQSAALYVSHG 238 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 A GLAQA QLHGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A A Sbjct 239 A-SGLAQATQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDESIAAA 297 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HR+AH CD +SA+GGVIA+N EVSVEMAE V+ IFTEVI+AP Y GA++VL++KKNIR+ Sbjct 298 HRQAHACDSVSAFGGVIASNREVSVEMAEQVAEIFTEVIIAPSYEEGAVEVLSQKKNIRI 357 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 L A P+ G E R ISGGLL+Q+ D + A GDNPANWTLA G L DL FAW A Sbjct 358 LQAEAPVREGFETREISGGLLVQERDLIHAEGDNPANWTLAAGEAVSAEVLKDLEFAWTA 417 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG-ERVRGAVAASDAFFPFPDGL 479 R+VKSNAI++A DGATVGVGMGQVNRVD+ARLAV+R G ER G+VAASDAFFPF DG Sbjct 418 VRSVKSNAILLAKDGATVGVGMGQVNRVDSARLAVDRAGEERATGSVAASDAFFPFADGF 477 Query 480 ETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E LA AG+TAVV PGGS+RD+EV EAA KAGVT+YLTGARHF+H Sbjct 478 EVLAQAGITAVVQPGGSIRDDEVIEAANKAGVTMYLTGARHFSH 521 >gi|296140985|ref|YP_003648228.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Tsukamurella paurometabola DSM 20162] gi|296029119|gb|ADG79889.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Tsukamurella paurometabola DSM 20162] Length=514 Score = 710 bits (1832), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/516 (69%), Positives = 418/516 (82%), Gaps = 7/516 (1%) Query 9 PIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLD 68 PI+RALISVYDK+GLV+LA GL+ AGVEI+STGSTA+ IAD G+PVT VE++TGFPE LD Sbjct 5 PIKRALISVYDKSGLVELATGLAQAGVEIVSTGSTARVIADAGVPVTRVEEVTGFPECLD 64 Query 69 GRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVE 128 GRVKTLHP++HAG+LAD R EH L +L ++ FELVVVNLYPFS TV SGA+ D+C+E Sbjct 65 GRVKTLHPKIHAGILADTRLPEHLEQLRELNVKKFELVVVNLYPFSDTVASGATEDECIE 124 Query 129 QIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEY 188 QIDIGGP+MVR AAKNHPS VV P Y V R G F+L ERK+ A+ AF+H A+Y Sbjct 125 QIDIGGPSMVRGAAKNHPSVTVVVSPDDYTAVTDRARTG-FSLEERKQFAAKAFRHTADY 183 Query 189 DIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALY-GDPTAWPGLAQ 247 D+AVAS++ +APE FP W G +W R A+LRYGENPHQ AALY G TA GLAQ Sbjct 184 DVAVASYLTNVVAPEADTG-FPAWMGGTWNRDAVLRYGENPHQGAALYVGGSTA--GLAQ 240 Query 248 AEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHEC 307 A+QLHGK+MSYNN+TD DAAWRAA+D + VAIIKHANPCGIAI VA AHRKAH C Sbjct 241 AQQLHGKEMSYNNYTDGDAAWRAAYDFREPAVAIIKHANPCGIAIGK-DVAQAHRKAHAC 299 Query 308 DPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPL 367 DP+SAYGGVIAAN EVS+EMAE VS IFTEVI+AP YA GA+ VL RKKNIRVL+A EP Sbjct 300 DPVSAYGGVIAANREVSLEMAEQVSEIFTEVIIAPAYADGAVAVLQRKKNIRVLLA-EPP 358 Query 368 AGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKSN 427 G+E++ I+GGLL+Q+SD +DA GD+PANWTLATG PAD ATL DL FAWRACRAVKSN Sbjct 359 VLGTEIKQITGGLLVQRSDAIDAEGDDPANWTLATGEPADEATLADLEFAWRACRAVKSN 418 Query 428 AIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGV 487 AI++A+ GA+VGVGMGQVNRVD+A+LAV+R G+RV G+VAASDAFFPFPDG + L AGV Sbjct 419 AILLASRGASVGVGMGQVNRVDSAQLAVKRAGDRVLGSVAASDAFFPFPDGPQILIDAGV 478 Query 488 TAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 A+V PGGS+RD+EV EAAA+AGVT+Y TG RHF H Sbjct 479 KAIVQPGGSIRDKEVVEAAAEAGVTMYFTGTRHFFH 514 >gi|324998096|ref|ZP_08119208.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Pseudonocardia sp. P1] Length=520 Score = 710 bits (1832), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/519 (70%), Positives = 412/519 (80%), Gaps = 4/519 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 RRP+RRALISVYDK GL+DLA GL AAGVEI+STGSTA+ IAD G+PVTPVE++TGFPE Sbjct 4 RRPVRRALISVYDKAGLLDLATGLHAAGVEIVSTGSTAQRIADAGVPVTPVEEVTGFPEC 63 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 DGRVKTLHPRVHAGLLAD RK EH LEQL I F+L+V NLYPF +TV SGAS D+ Sbjct 64 FDGRVKTLHPRVHAGLLADTRKDEHVVQLEQLNIAPFDLLVSNLYPFRETVASGASRDEA 123 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGPAMVRA+AKNH S AVV +P Y VL + AGGF +A+R+RLA+ AF+H A Sbjct 124 VEQIDIGGPAMVRASAKNHESVAVVVEPSRYEWVLEQVAAGGFVVADRRRLAADAFRHTA 183 Query 187 EYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLA 246 YD++VA+WM + A P+WFG +W R LRYGENPHQ AALY D A GLA Sbjct 184 AYDVSVATWMGEQFPAGDGTEATPEWFGATWTRERALRYGENPHQAAALYADGGA-TGLA 242 Query 247 QAEQLHGKDMSYNNFTDADAAWRAAFDH-EQTCVAIIKHANPCGIAISSVSVADAHRKAH 305 AEQLHGK+MSYNN+ DADAAWRAA DH ++ VA+IKHANPCGIA+ + VA+AHRKAH Sbjct 243 GAEQLHGKEMSYNNYVDADAAWRAAHDHGDRPTVAVIKHANPCGIAVGA-DVAEAHRKAH 301 Query 306 ECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVL-VAA 364 DP+SA+GGV+A N EVSV MAE V+ IFTEV+VAP YA GAL+VL RKKN+R+L + Sbjct 302 ATDPVSAFGGVVAVNGEVSVAMAEQVAEIFTEVVVAPSYADGALEVLQRKKNVRLLRIPG 361 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 E GG+ELRPISGG+L+QQ D +DA GD+PA W L TG PA P L DL FAWRACRAV Sbjct 362 EVARGGTELRPISGGVLVQQRDLVDAAGDDPAAWKLVTGDPASPELLADLAFAWRACRAV 421 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAA 484 KSNAI++A DGA VGVGMGQVNRVDAA+LAVER G+RVRGAV ASDAFFPFPDGLE L Sbjct 422 KSNAILLAHDGAAVGVGMGQVNRVDAAKLAVERAGDRVRGAVVASDAFFPFPDGLEVLLD 481 Query 485 AGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AGV AVV PGGSVRDE+V A AKAGV +YLTG RHFAH Sbjct 482 AGVAAVVQPGGSVRDEQVVAACAKAGVPMYLTGTRHFAH 520 >gi|294814566|ref|ZP_06773209.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces clavuligerus ATCC 27064] gi|326442956|ref|ZP_08217690.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces clavuligerus ATCC 27064] gi|294327165|gb|EFG08808.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces clavuligerus ATCC 27064] Length=535 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/520 (70%), Positives = 409/520 (79%), Gaps = 4/520 (0%) Query 7 RRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEV 66 RRP+RRAL+SVYDKTGL DLA+GL AGVE++STGSTA IA G+PVT VE+LTGFPE Sbjct 17 RRPVRRALVSVYDKTGLEDLARGLHEAGVELVSTGSTAGRIAAAGVPVTKVEELTGFPEC 76 Query 67 LDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDC 126 LDGRVKTLHPRVHAG+LADLR H L +LG+E F+LVVVNLYPF TVESGAS D+C Sbjct 77 LDGRVKTLHPRVHAGILADLRLESHREQLAELGVEPFDLVVVNLYPFRATVESGASPDEC 136 Query 127 VEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIA 186 VEQIDIGGP+MVRAAAKNHPS AVVT P Y VL+A+ AGGF LA RKRLA+ AFQH A Sbjct 137 VEQIDIGGPSMVRAAAKNHPSVAVVTSPARYGDVLSAVAAGGFDLAARKRLAAEAFQHTA 196 Query 187 EYDIAVASWMQQTLAPEHPVA--AFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 YD+AVASW + AP+ A FP + G ++ R +LRYGENPHQ AAL+ G Sbjct 197 AYDLAVASWFARAYAPDESAAEGGFPDFIGVAYERAQVLRYGENPHQGAALFTYVDGAGG 256 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LA AEQLHGK+MSYNN+TD DAA RAA+DH VAIIKHANPCGIA + VA+AHRKA Sbjct 257 LAGAEQLHGKEMSYNNYTDTDAARRAAYDHAGPAVAIIKHANPCGIA-TGADVAEAHRKA 315 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CDPLSA+GGVIA N VSV MAE V+ +FTEVI+APGY GA++VLARKKNIRVL A Sbjct 316 HACDPLSAFGGVIAVNRPVSVAMAEQVAEVFTEVIIAPGYEDGAVEVLARKKNIRVLRCA 375 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 A E RPI GG L+Q +D+L A GD+PANWTLATG P D A L DL FAWRACRAV Sbjct 376 GAPAAPVEARPIDGGTLVQVADRLQAAGDDPANWTLATGEPLDEAGLADLAFAWRACRAV 435 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVERGG-ERVRGAVAASDAFFPFPDGLETLA 483 KSNAI++A DGA+VGVGMGQVNRVD+A+LAVER G ER RG+ AASDAFFPFPDGLE L Sbjct 436 KSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGSYAASDAFFPFPDGLEILT 495 Query 484 AAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AAGV AVV PGGSVRDE+V EAA AGVT+Y TG RHF H Sbjct 496 AAGVRAVVQPGGSVRDEQVVEAAKAAGVTMYFTGTRHFFH 535 >gi|19552088|ref|NP_600090.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium glutamicum ATCC 13032] gi|62389751|ref|YP_225153.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Corynebacterium glutamicum ATCC 13032] gi|29336779|sp|Q8NS21.1|PUR9_CORGL RecName: Full=Bifunctional purine biosynthesis protein purH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase gi|21323627|dbj|BAB98254.1| AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Corynebacterium glutamicum ATCC 13032] gi|41325086|emb|CAF19567.1| 5'-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE-4-CARBOXYLASE [Corynebacterium glutamicum ATCC 13032] Length=520 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/520 (67%), Positives = 406/520 (79%), Gaps = 3/520 (0%) Query 5 DGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFP 64 D R+ I+RALISVYDKTGL DLAQ L VEI+STGSTA IA+ GIPVTPVE+LTGFP Sbjct 3 DDRKAIKRALISVYDKTGLEDLAQALHRENVEIVSTGSTAAKIAELGIPVTPVEELTGFP 62 Query 65 EVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVD 124 E L+GRVKTLHP+VHAG+LAD RK +H L++L + F+LVVVNLYPF++TV SGA D Sbjct 63 ECLEGRVKTLHPKVHAGILADTRKEDHLRQLKELEVAPFQLVVVNLYPFAETVASGADFD 122 Query 125 DCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQH 184 CVEQIDIGGP+MVRAAAKNHPS AVV P Y V AL+ GGF+ AER +LA+ AF+H Sbjct 123 ACVEQIDIGGPSMVRAAAKNHPSVAVVVSPNRYEDVQEALKTGGFSRAERTKLAAEAFRH 182 Query 185 IAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPG 244 A YD+ VA+WM + LA E FP W G + LRYGENPHQ AALY T G Sbjct 183 TATYDVTVATWMSEQLAAEDSETEFPGWIGTTNTLSRSLRYGENPHQSAALYVGNT--RG 240 Query 245 LAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKA 304 LAQA+Q HGK+MSYNN+TD+DAAWRAA+DHE+ CVAIIKHANPCGIA+S S+A AHR+A Sbjct 241 LAQAKQFHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDESIAAAHREA 300 Query 305 HECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAA 364 H CD +SA+GGVIA+N EVSVEMA V+ IFTEVI+AP Y GA+++L++KKNIR+L A Sbjct 301 HACDSVSAFGGVIASNREVSVEMANQVAEIFTEVIIAPSYEEGAVEILSQKKNIRILQAE 360 Query 365 EPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAV 424 P+ G E R ISGGLL+Q+ D + A GDN ANWTLA GS P L DL FAW A R+V Sbjct 361 APVRKGFESREISGGLLVQERDLIHAEGDNSANWTLAAGSAVSPEVLKDLEFAWTAVRSV 420 Query 425 KSNAIVIAADGATVGVGMGQVNRVDAARLAVER-GGERVRGAVAASDAFFPFPDGLETLA 483 KSNAI++A +GATVGVGMGQVNRVD+ARLAV+R G ER G+VAASDAFFPF DG E LA Sbjct 421 KSNAILLAKNGATVGVGMGQVNRVDSARLAVDRAGAERATGSVAASDAFFPFADGFEVLA 480 Query 484 AAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 AG+TAVV PGGS+RD EV EAA KAGVT+YLTGARHFAH Sbjct 481 EAGITAVVQPGGSIRDNEVIEAANKAGVTMYLTGARHFAH 520 >gi|302553660|ref|ZP_07306002.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces viridochromogenes DSM 40736] gi|302471278|gb|EFL34371.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Streptomyces viridochromogenes DSM 40736] Length=520 Score = 701 bits (1809), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/524 (68%), Positives = 409/524 (79%), Gaps = 5/524 (0%) Query 1 MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL 60 M+ + +RP+RRAL+SVYDKTGL +LA+GL AGVE++STGSTA IA G+PVT VE+L Sbjct 1 MTAESNKRPLRRALVSVYDKTGLEELARGLDEAGVELVSTGSTAAKIAAAGVPVTKVEEL 60 Query 61 TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG 120 TGFPE LDGRVKTLHPRVHAG+LADLR +H L +LG+E F+LVVVNLYPF +TV SG Sbjct 61 TGFPECLDGRVKTLHPRVHAGILADLRLEDHQRQLAELGVEPFDLVVVNLYPFRETVASG 120 Query 121 ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL 180 AS D+CVEQIDIGGP+MVRAAAKNHPS A+VT P Y VL A R+GGF L+ RKRLA+ Sbjct 121 ASPDECVEQIDIGGPSMVRAAAKNHPSVAIVTSPARYADVLEAARSGGFDLSTRKRLAAE 180 Query 181 AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT 240 AFQH A YD+AVASW + AP + FP + G +W R LRYGENPHQ AALY T Sbjct 181 AFQHTAAYDVAVASWFASSYAPVDE-SEFPDFLGATWEREHTLRYGENPHQPAALYVSGT 239 Query 241 AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA 300 GLA+AEQLHGK+MSYNN+TD DAA RAA+DH + VAIIKHANPCGIA+ S VA+A Sbjct 240 G--GLAEAEQLHGKEMSYNNYTDTDAARRAAYDHTEPAVAIIKHANPCGIAVGS-DVAEA 296 Query 301 HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV 360 HRKAH CDPLSA+GGVIA N VS EMAE V+ IFTEVIVAP Y GAL+ L +KKNIRV Sbjct 297 HRKAHACDPLSAFGGVIAVNRPVSKEMAEQVAEIFTEVIVAPDYEDGALEALTKKKNIRV 356 Query 361 LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA 420 L E + E++PI GG L+Q +D+L A GD+PANWTLATG L++L FAW+A Sbjct 357 LRCPEGPSAPVEVKPIDGGALLQVTDRLQADGDDPANWTLATGEALSAEELSELAFAWKA 416 Query 421 CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVER-GGERVRGAVAASDAFFPFPDGL 479 CRAVKSNAI++A DGA+VGVGMGQVNRVD+A+LAVER G ER RG+ AASDAFFPFPDGL Sbjct 417 CRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGAERARGSYAASDAFFPFPDGL 476 Query 480 ETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH 523 E L AGV AVV PGGSVRDE V EAA KAGVT+Y TG RHF H Sbjct 477 EILTEAGVKAVVQPGGSVRDELVVEAARKAGVTMYFTGTRHFFH 520 Lambda K H 0.318 0.132 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1147160078884 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40