BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0992c
Length=197
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608132|ref|NP_215507.1| hypothetical protein Rv0992c [Mycob... 380 8e-104
gi|253799980|ref|YP_003032981.1| hypothetical protein TBMG_02997... 379 1e-103
gi|31792183|ref|NP_854676.1| hypothetical protein Mb1019c [Mycob... 378 2e-103
gi|121636919|ref|YP_977142.1| hypothetical protein BCG_1047c [My... 376 8e-103
gi|15840417|ref|NP_335454.1| hypothetical protein MT1021 [Mycoba... 375 1e-102
gi|15826993|ref|NP_301256.1| hypothetical protein ML0181 [Mycoba... 280 9e-74
gi|254823440|ref|ZP_05228441.1| 5,10-methenyltetrahydrofolate sy... 262 2e-68
gi|118619765|ref|YP_908097.1| hypothetical protein MUL_4694 [Myc... 251 3e-65
gi|289555226|ref|ZP_06444436.1| conserved hypothetical protein [... 250 1e-64
gi|118465305|ref|YP_880354.1| 5,10-methenyltetrahydrofolate synt... 245 3e-63
gi|336461403|gb|EGO40274.1| 5,10-methenyltetrahydrofolate synthe... 241 3e-62
gi|41407021|ref|NP_959857.1| hypothetical protein MAP0923c [Myco... 240 7e-62
gi|183984492|ref|YP_001852783.1| hypothetical protein MMAR_4522 ... 239 1e-61
gi|240169341|ref|ZP_04748000.1| hypothetical protein MkanA1_0851... 238 4e-61
gi|342860586|ref|ZP_08717237.1| 5-formyltetrahydrofolate cyclo-l... 233 1e-59
gi|296169799|ref|ZP_06851413.1| possible 5-formyltetrahydrofolat... 233 2e-59
gi|118470364|ref|YP_889710.1| 5,10-methenyltetrahydrofolate synt... 213 2e-53
gi|333989580|ref|YP_004522194.1| hypothetical protein JDM601_094... 201 7e-50
gi|120405784|ref|YP_955613.1| 5-formyltetrahydrofolate cyclo-lig... 197 5e-49
gi|108801255|ref|YP_641452.1| 5-formyltetrahydrofolate cyclo-lig... 190 1e-46
gi|126437234|ref|YP_001072925.1| 5-formyltetrahydrofolate cyclo-... 187 8e-46
gi|254773981|ref|ZP_05215497.1| 5,10-methenyltetrahydrofolate sy... 186 2e-45
gi|145222486|ref|YP_001133164.1| 5-formyltetrahydrofolate cyclo-... 182 3e-44
gi|315442933|ref|YP_004075812.1| 5,10-methenyltetrahydrofolate s... 182 3e-44
gi|312138620|ref|YP_004005956.1| 5-formyltetrahydrofolate cyclo-... 159 2e-37
gi|226307877|ref|YP_002767837.1| hypothetical protein RER_43900 ... 157 8e-37
gi|111022597|ref|YP_705569.1| hypothetical protein RHA1_ro05631 ... 156 1e-36
gi|229495035|ref|ZP_04388781.1| 5-formyltetrahydrofolate cyclo-l... 156 2e-36
gi|325676313|ref|ZP_08155992.1| 5-formyltetrahydrofolate cyclo-l... 155 4e-36
gi|226365105|ref|YP_002782888.1| 5-formyltetrahydrofolate cyclo-... 152 3e-35
gi|257057233|ref|YP_003135065.1| 5,10-methenyltetrahydrofolate s... 141 4e-32
gi|169628180|ref|YP_001701829.1| 5-formyltetrahydrofolate cyclo-... 140 1e-31
gi|300790120|ref|YP_003770411.1| 5-formyltetrahydrofolate cyclo-... 134 5e-30
gi|54026928|ref|YP_121170.1| hypothetical protein nfa49540 [Noca... 131 5e-29
gi|343925211|ref|ZP_08764738.1| hypothetical protein GOALK_038_0... 127 6e-28
gi|256374776|ref|YP_003098436.1| 5-formyltetrahydrofolate cyclo-... 122 2e-26
gi|134097379|ref|YP_001103040.1| 5-formyltetrahydrofolate cyclo-... 122 3e-26
gi|302530353|ref|ZP_07282695.1| 5-formyltetrahydrofolate cyclo-l... 121 4e-26
gi|291009063|ref|ZP_06567036.1| 5-formyltetrahydrofolate cyclo-l... 121 6e-26
gi|262201379|ref|YP_003272587.1| 5-formyltetrahydrofolate cyclo-... 119 2e-25
gi|319950607|ref|ZP_08024515.1| hypothetical protein ES5_13518 [... 117 7e-25
gi|333921215|ref|YP_004494796.1| 5-formyltetrahydrofolate cyclo-... 117 8e-25
gi|255325458|ref|ZP_05366562.1| 5-formyltetrahydrofolate cyclo-l... 113 1e-23
gi|311740867|ref|ZP_07714694.1| 5-formyltetrahydrofolate cyclo-l... 113 2e-23
gi|296140950|ref|YP_003648193.1| 5-formyltetrahydrofolate cyclo-... 113 2e-23
gi|317507880|ref|ZP_07965578.1| 5-formyltetrahydrofolate cyclo-l... 104 6e-21
gi|300781679|ref|ZP_07091533.1| 5-formyltetrahydrofolate cyclo-l... 103 1e-20
gi|297563016|ref|YP_003681990.1| 5-formyltetrahydrofolate cyclo-... 102 2e-20
gi|326383763|ref|ZP_08205448.1| 5-formyltetrahydrofolate cyclo-l... 102 3e-20
gi|312133845|ref|YP_004001184.1| 5-formyltetrahydrofolate cyclo-... 100 1e-19
>gi|15608132|ref|NP_215507.1| hypothetical protein Rv0992c [Mycobacterium tuberculosis H37Rv]
gi|148660773|ref|YP_001282296.1| hypothetical protein MRA_0999 [Mycobacterium tuberculosis H37Ra]
gi|148822201|ref|YP_001286955.1| hypothetical protein TBFG_11010 [Mycobacterium tuberculosis F11]
40 more sequence titles
Length=197
Score = 380 bits (975), Expect = 8e-104, Method: Compositional matrix adjust.
Identities = 197/197 (100%), Positives = 197/197 (100%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE
Sbjct 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ
Sbjct 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM
Sbjct 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
Query 181 THALTPERGLIALPCGE 197
THALTPERGLIALPCGE
Sbjct 181 THALTPERGLIALPCGE 197
>gi|253799980|ref|YP_003032981.1| hypothetical protein TBMG_02997 [Mycobacterium tuberculosis KZN
1435]
gi|254231289|ref|ZP_04924616.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
gi|254363910|ref|ZP_04979956.1| conserved hypothetical protein [Mycobacterium tuberculosis str.
Haarlem]
10 more sequence titles
Length=223
Score = 379 bits (974), Expect = 1e-103, Method: Compositional matrix adjust.
Identities = 197/197 (100%), Positives = 197/197 (100%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE
Sbjct 27 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 86
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ
Sbjct 87 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 146
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM
Sbjct 147 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 206
Query 181 THALTPERGLIALPCGE 197
THALTPERGLIALPCGE
Sbjct 207 THALTPERGLIALPCGE 223
>gi|31792183|ref|NP_854676.1| hypothetical protein Mb1019c [Mycobacterium bovis AF2122/97]
gi|289442412|ref|ZP_06432156.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium tuberculosis
T46]
gi|289446573|ref|ZP_06436317.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
15 more sequence titles
Length=197
Score = 378 bits (971), Expect = 2e-103, Method: Compositional matrix adjust.
Identities = 196/197 (99%), Positives = 197/197 (100%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA+ASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE
Sbjct 1 MAIASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ
Sbjct 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM
Sbjct 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
Query 181 THALTPERGLIALPCGE 197
THALTPERGLIALPCGE
Sbjct 181 THALTPERGLIALPCGE 197
>gi|121636919|ref|YP_977142.1| hypothetical protein BCG_1047c [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224989391|ref|YP_002644078.1| hypothetical protein JTY_1019 [Mycobacterium bovis BCG str. Tokyo
172]
gi|121492566|emb|CAL71034.1| Conserved hypothetical protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224772504|dbj|BAH25310.1| hypothetical protein JTY_1019 [Mycobacterium bovis BCG str. Tokyo
172]
gi|341600935|emb|CCC63606.1| conserved hypothetical protein [Mycobacterium bovis BCG str.
Moreau RDJ]
Length=197
Score = 376 bits (966), Expect = 8e-103, Method: Compositional matrix adjust.
Identities = 195/197 (99%), Positives = 196/197 (99%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA+ASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE
Sbjct 1 MAIASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ
Sbjct 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
ASLVLVPALAVDRQ VRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM
Sbjct 121 ASLVLVPALAVDRQSVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
Query 181 THALTPERGLIALPCGE 197
THALTPERGLIALPCGE
Sbjct 181 THALTPERGLIALPCGE 197
>gi|15840417|ref|NP_335454.1| hypothetical protein MT1021 [Mycobacterium tuberculosis CDC1551]
gi|13880587|gb|AAK45268.1| 5-formyltetrahydrofolate cyclo-ligase-related protein [Mycobacterium
tuberculosis CDC1551]
Length=195
Score = 375 bits (964), Expect = 1e-102, Method: Compositional matrix adjust.
Identities = 195/195 (100%), Positives = 195/195 (100%), Gaps = 0/195 (0%)
Query 3 MASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEML 62
MASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEML
Sbjct 1 MASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEML 60
Query 63 DVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQAS 122
DVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQAS
Sbjct 61 DVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQAS 120
Query 123 LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH 182
LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH
Sbjct 121 LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH 180
Query 183 ALTPERGLIALPCGE 197
ALTPERGLIALPCGE
Sbjct 181 ALTPERGLIALPCGE 195
>gi|15826993|ref|NP_301256.1| hypothetical protein ML0181 [Mycobacterium leprae TN]
gi|221229471|ref|YP_002502887.1| hypothetical protein MLBr_00181 [Mycobacterium leprae Br4923]
gi|4455709|emb|CAB36695.1| hypothetical protein MLCB373.33c [Mycobacterium leprae]
gi|13092540|emb|CAC29689.1| conserved hypothetical protein [Mycobacterium leprae]
gi|219932578|emb|CAR70274.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=197
Score = 280 bits (716), Expect = 9e-74, Method: Compositional matrix adjust.
Identities = 143/197 (73%), Positives = 161/197 (82%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M ASK+ LR QLLAARR VADD+RAAE +ML HLE +V S STVCAYVPVG EPG+IE
Sbjct 1 MVTASKATLRKQLLAARRSVADDIRAAETKMLSQHLELLVNSASTVCAYVPVGTEPGAIE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLLR+ GRVLLPVART ++PLPL+WGEYR GGL WGLLEPPE LPE+ALA+
Sbjct 61 MLDVLLRKTGRVLLPVARTGDDEIPLPLQWGEYRPGGLTSGPWGLLEPPELRLPESALAE 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A+LVLVPALAVD GVRLGRG GFYDRSL RDPH L+A+VR EL++ LPSEPHDV M
Sbjct 121 ANLVLVPALAVDHHGVRLGRGGGFYDRSLAGRDPHTLLIALVRDTELLNELPSEPHDVRM 180
Query 181 THALTPERGLIALPCGE 197
THA+TPERG+IALP E
Sbjct 181 THAVTPERGVIALPNSE 197
>gi|254823440|ref|ZP_05228441.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium intracellulare
ATCC 13950]
Length=199
Score = 262 bits (670), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 150/196 (77%), Positives = 165/196 (85%), Gaps = 3/196 (1%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLE---RMVTSDSTVCAYVPVGGEPG 57
MA K+ALR+QLLAARRRVADDVRAAEA +LR LE +V SDSTVCAYVPVG EPG
Sbjct 1 MATTGKAALREQLLAARRRVADDVRAAEADLLREKLEAPESIVASDSTVCAYVPVGTEPG 60
Query 58 SIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAA 117
SIE+LD+LLRRAGRVLLPVART + PLPL WGEYR G L RWGLLEPP+PWLP AA
Sbjct 61 SIELLDMLLRRAGRVLLPVARTTADNTPLPLSWGEYRPGTLTTGRWGLLEPPQPWLPAAA 120
Query 118 LAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHD 177
LA+A+LVLVPALAVDR GVRLGRGRGFYDRSL RDPHA LVA+VR EL+D +P+ PHD
Sbjct 121 LAEAALVLVPALAVDRAGVRLGRGRGFYDRSLGGRDPHAPLVALVRDAELLDEIPAGPHD 180
Query 178 VPMTHALTPERGLIAL 193
VPMTHALTP+RGLIAL
Sbjct 181 VPMTHALTPQRGLIAL 196
>gi|118619765|ref|YP_908097.1| hypothetical protein MUL_4694 [Mycobacterium ulcerans Agy99]
gi|118571875|gb|ABL06626.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
Length=197
Score = 251 bits (642), Expect = 3e-65, Method: Compositional matrix adjust.
Identities = 129/197 (66%), Positives = 153/197 (78%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K+A+R +L ARR V D+V AAEA +L HL +++ +TVC YVPVG EPGSI
Sbjct 1 MTSVNKAAMRARLRQARRVVPDEVHAAEALLLDAHLAQVIDGGATVCGYVPVGTEPGSIP 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLL+ RVLLPVART GD PLPL WGEYR G L R RWGLLEPP PWLPE+A+ Q
Sbjct 61 MLDVLLQHGARVLLPVARTTDGDGPLPLMWGEYRPGELVRGRWGLLEPPAPWLPESAVGQ 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
ASLVL+PALAVD +GVRLG+G GFYDRSL R+P ARL+A+VR E+VD LPSEPHDV M
Sbjct 121 ASLVLLPALAVDLEGVRLGKGLGFYDRSLTNRNPQARLLAIVRDEEVVDRLPSEPHDVRM 180
Query 181 THALTPERGLIALPCGE 197
THA+TP+RG+I+ P E
Sbjct 181 THAITPQRGIISFPHRE 197
>gi|289555226|ref|ZP_06444436.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
gi|289439858|gb|EFD22351.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
Length=135
Score = 250 bits (638), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 128/128 (100%), Positives = 128/128 (100%), Gaps = 0/128 (0%)
Query 70 GRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASLVLVPAL 129
GRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASLVLVPAL
Sbjct 8 GRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASLVLVPAL 67
Query 130 AVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHALTPERG 189
AVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHALTPERG
Sbjct 68 AVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHALTPERG 127
Query 190 LIALPCGE 197
LIALPCGE
Sbjct 128 LIALPCGE 135
>gi|118465305|ref|YP_880354.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium avium
104]
gi|118166592|gb|ABK67489.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium avium
104]
Length=196
Score = 245 bits (625), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 152/193 (79%), Positives = 166/193 (87%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA K+ALR++LLAARRRVADDVRAAEARMLR LE MVTS STVCAYVPVG EPGS+E
Sbjct 1 MATTGKAALRERLLAARRRVADDVRAAEARMLREQLEFMVTSGSTVCAYVPVGAEPGSVE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD+LLRRAGRVLLPVARTA D PLPL WGEYR G L RWGLLEP +PWLP +ALA
Sbjct 61 MLDMLLRRAGRVLLPVARTAADDTPLPLCWGEYRPGTLTTGRWGLLEPAQPWLPASALAD 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A+LVLVPALAVDR+GVRLGRGRGFYDRSL RDP ARLVA+VR EL+D LP+EPHDVPM
Sbjct 121 AALVLVPALAVDRRGVRLGRGRGFYDRSLGDRDPRARLVALVRDAELLDELPAEPHDVPM 180
Query 181 THALTPERGLIAL 193
THALTP+RGL+ L
Sbjct 181 THALTPQRGLVTL 193
>gi|336461403|gb|EGO40274.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium avium
subsp. paratuberculosis S397]
Length=196
Score = 241 bits (616), Expect = 3e-62, Method: Compositional matrix adjust.
Identities = 150/193 (78%), Positives = 165/193 (86%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA K+ALR++LLAARRRVADDVRAAEARMLR LE MVTS STVCAYVPVG EPGS+E
Sbjct 1 MATTGKAALRERLLAARRRVADDVRAAEARMLREQLEFMVTSGSTVCAYVPVGAEPGSVE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD+LLRRAGRVLLPVARTA + PLPL WGEYR G L RWGLLEP +PWLP +ALA
Sbjct 61 MLDMLLRRAGRVLLPVARTAADNTPLPLCWGEYRPGTLTTGRWGLLEPAQPWLPASALAD 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A+LVLVPALAVDR+GVRLGRGRGFYDRSL RDP ARLVA+VR EL+D LP+EPHDVPM
Sbjct 121 AALVLVPALAVDRRGVRLGRGRGFYDRSLGDRDPRARLVALVRDAELLDELPAEPHDVPM 180
Query 181 THALTPERGLIAL 193
THALTP+RG + L
Sbjct 181 THALTPQRGWVTL 193
>gi|41407021|ref|NP_959857.1| hypothetical protein MAP0923c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41395372|gb|AAS03240.1| hypothetical protein MAP_0923c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=232
Score = 240 bits (613), Expect = 7e-62, Method: Compositional matrix adjust.
Identities = 150/193 (78%), Positives = 165/193 (86%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA K+ALR++LLAARRRVADDVRAAEARMLR LE MVTS STVCAYVPVG EPGS+E
Sbjct 37 MATTGKAALRERLLAARRRVADDVRAAEARMLREQLEFMVTSGSTVCAYVPVGAEPGSVE 96
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD+LLRRAGRVLLPVARTA + PLPL WGEYR G L RWGLLEP +PWLP +ALA
Sbjct 97 MLDMLLRRAGRVLLPVARTAADNTPLPLCWGEYRPGTLTTGRWGLLEPAQPWLPASALAD 156
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A+LVLVPALAVDR+GVRLGRGRGFYDRSL RDP ARLVA+VR EL+D LP+EPHDVPM
Sbjct 157 AALVLVPALAVDRRGVRLGRGRGFYDRSLGDRDPRARLVALVRDAELLDELPAEPHDVPM 216
Query 181 THALTPERGLIAL 193
THALTP+RG + L
Sbjct 217 THALTPQRGWVTL 229
>gi|183984492|ref|YP_001852783.1| hypothetical protein MMAR_4522 [Mycobacterium marinum M]
gi|183177818|gb|ACC42928.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=197
Score = 239 bits (610), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 129/197 (66%), Positives = 152/197 (78%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K+A+R +L ARR V DDV AAEA +L HL +++ +TVC YVPVG EPGSI
Sbjct 1 MTSVNKAAMRARLRQARRLVPDDVHAAEALLLDAHLAQVIDGGATVCGYVPVGTEPGSIT 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLDVLL+ RVLLPVART GD PLPL WGEYR G L R RWGLLEPP PWLPE+A+ Q
Sbjct 61 MLDVLLQHGARVLLPVARTTDGDGPLPLMWGEYRPGELVRGRWGLLEPPAPWLPESAVGQ 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A LVL+PALAVD +GVRLG+G GFYDRSL R+P ARL+A+VR E+VD LPSEPHDV M
Sbjct 121 AGLVLLPALAVDLEGVRLGKGLGFYDRSLANRNPQARLLAIVRDEEVVDRLPSEPHDVRM 180
Query 181 THALTPERGLIALPCGE 197
THA+TP+RG+I+ P E
Sbjct 181 THAMTPQRGVISFPHRE 197
>gi|240169341|ref|ZP_04748000.1| hypothetical protein MkanA1_08511 [Mycobacterium kansasii ATCC
12478]
Length=198
Score = 238 bits (607), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 135/197 (69%), Positives = 154/197 (79%), Gaps = 0/197 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M A K+ALR ++LAARR VADDVRA EA + HLE +V+ +TVCAYVPVGGEPGSI+
Sbjct 1 MTSAGKAALRRRVLAARRLVADDVRATEAGLFTRHLEPLVSCHTTVCAYVPVGGEPGSID 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
ML L R A RVLLPVAR A +PLPL WGEYR G L R RWGLLEPPEPWL E+A+A+
Sbjct 61 MLMALRRCAARVLLPVARVAADKVPLPLLWGEYRPGELVRGRWGLLEPPEPWLQESAVAE 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A LVLVPALAVDR+GVRLG+G GFYDRSL +PH RL+A++R ELVD LP E HDV M
Sbjct 121 ADLVLVPALAVDRRGVRLGKGLGFYDRSLAGMNPHTRLIALIRDEELVDDLPQEAHDVRM 180
Query 181 THALTPERGLIALPCGE 197
TH +TP RGLIALPCG
Sbjct 181 THVITPARGLIALPCGN 197
>gi|342860586|ref|ZP_08717237.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium colombiense
CECT 3035]
gi|342132241|gb|EGT85482.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium colombiense
CECT 3035]
Length=199
Score = 233 bits (594), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 142/196 (73%), Positives = 159/196 (82%), Gaps = 3/196 (1%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERM---VTSDSTVCAYVPVGGEPG 57
MA SK+ALRDQLLAARR VADDVRAAEA L LE + VTSDST+CAYVPVG EPG
Sbjct 1 MATTSKAALRDQLLAARRHVADDVRAAEAHQLCERLEALEGVVTSDSTICAYVPVGTEPG 60
Query 58 SIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAA 117
SIEMLD+LLRR R+LLPVART + PLPL WGEYR G L RWGLLEPP PWLP +A
Sbjct 61 SIEMLDMLLRRTRRLLLPVARTTADNTPLPLSWGEYRPGTLTTGRWGLLEPPRPWLPSSA 120
Query 118 LAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHD 177
LAQA +VLVPALAVDR+GVRLGRGRGFYDRSL R PHARL+AVVR E++D +P++ HD
Sbjct 121 LAQAGVVLVPALAVDRRGVRLGRGRGFYDRSLGGRGPHARLIAVVRDAEVLDEVPADSHD 180
Query 178 VPMTHALTPERGLIAL 193
+PMTHALTP +GLI L
Sbjct 181 IPMTHALTPRQGLIDL 196
>gi|296169799|ref|ZP_06851413.1| possible 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295895476|gb|EFG75176.1| possible 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=205
Score = 233 bits (593), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 144/196 (74%), Positives = 160/196 (82%), Gaps = 3/196 (1%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLE---RMVTSDSTVCAYVPVGGEPG 57
MA SK+ALR+QL AARRRVAD+VRA EARMLR HLE +V+ D TVCAYVPVG EPG
Sbjct 1 MATTSKAALREQLQAARRRVADEVRAGEARMLRAHLEAAESIVSGDDTVCAYVPVGAEPG 60
Query 58 SIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAA 117
SIEM+D LLRRA RVLLPVART + PLRWGEYR G L ARWGLLEPP+PWLP +A
Sbjct 61 SIEMVDALLRRARRVLLPVARTGADNAAQPLRWGEYRPGTLTSARWGLLEPPQPWLPASA 120
Query 118 LAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHD 177
+A+A L+LVP+LAVDR+GVRLGRGRGFYDRSL RDP ARLVAVVR ELVD LP+E HD
Sbjct 121 IAEAGLILVPSLAVDRRGVRLGRGRGFYDRSLGHRDPGARLVAVVRDAELVDQLPAEAHD 180
Query 178 VPMTHALTPERGLIAL 193
+PMTHALTP GLI L
Sbjct 181 IPMTHALTPRGGLIPL 196
>gi|118470364|ref|YP_889710.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium smegmatis
str. MC2 155]
gi|118171651|gb|ABK72547.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium smegmatis
str. MC2 155]
Length=194
Score = 213 bits (541), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 112/193 (59%), Positives = 134/193 (70%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M+ SKS LR LL RR V + VR EA LRG L + S TVCAYVPVG EPGSI
Sbjct 1 MSPRSKSQLRTALLQNRRSVPEAVREGEAEALRGWLSGLKISGRTVCAYVPVGSEPGSIA 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
+LD LL RVLLPVAR +PLPL+WG+YR G L A +GL EPP PWLP + +
Sbjct 61 LLDTLLELGARVLLPVARNDAAGIPLPLQWGKYRPGTLVAAEFGLREPPPPWLPAETIGE 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A ++LVPALAVDR G RLGRG GFYDR+L A+++AVVR EL+D +P+EPHDV M
Sbjct 121 ADVILVPALAVDRSGARLGRGAGFYDRTLHHAAATAQVIAVVRDDELLDEIPAEPHDVAM 180
Query 181 THALTPERGLIAL 193
TH LTP+RG++AL
Sbjct 181 THVLTPKRGIVAL 193
>gi|333989580|ref|YP_004522194.1| hypothetical protein JDM601_0940 [Mycobacterium sp. JDM601]
gi|333485548|gb|AEF34940.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=198
Score = 201 bits (510), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 120/192 (63%), Positives = 136/192 (71%), Gaps = 0/192 (0%)
Query 2 AMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEM 61
A+ +KSALR +LLAARR V DV AEAR L GHLE++ TVCAYVPVG EPGS M
Sbjct 6 AVTAKSALRARLLAARRAVPPDVHDAEARALAGHLEQLAGGAHTVCAYVPVGSEPGSTAM 65
Query 62 LDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQA 121
LD L +R RVLLPV RT PL L WGEYR L +GLLEP PWLP LA+A
Sbjct 66 LDRLTQRGIRVLLPVVRTEDDGTPLALMWGEYRPENLVPGPFGLLEPTPPWLPAEVLAEA 125
Query 122 SLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMT 181
L++VPALA+DR+G RLGRG GFYDRSL R P LVAVVR EL+D LP+EPHDV MT
Sbjct 126 DLIVVPALAIDRRGARLGRGAGFYDRSLLLRRPQIPLVAVVRDTELLDELPAEPHDVSMT 185
Query 182 HALTPERGLIAL 193
HALTP G++AL
Sbjct 186 HALTPGLGVVAL 197
>gi|120405784|ref|YP_955613.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium vanbaalenii
PYR-1]
gi|119958602|gb|ABM15607.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium vanbaalenii
PYR-1]
Length=202
Score = 197 bits (502), Expect = 5e-49, Method: Compositional matrix adjust.
Identities = 105/189 (56%), Positives = 132/189 (70%), Gaps = 0/189 (0%)
Query 5 SKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLDV 64
+K+ +R ++L ARR + EA L HL+ ++ + VCA++PVG EPGSI M+D
Sbjct 4 TKAQVRAEILTARRSLTQQQHDREAAQLAAHLKALIAPGTVVCAFIPVGSEPGSIAMVDD 63
Query 65 LLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASLV 124
L+ R VLLPVAR PLP+RWG + G +A+A +GL EP PWLP A+ +AS+V
Sbjct 64 LVHRGVEVLLPVAREDIDGTPLPIRWGPHTPGAVAKAPFGLREPHPPWLPPEAVGRASVV 123
Query 125 LVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHAL 184
LVPALAVDR G RLGRG GFYDR+L D A LVAVVR E+VD LPSEPHDV MTHAL
Sbjct 124 LVPALAVDRSGARLGRGAGFYDRTLPLADADAWLVAVVRDDEVVDHLPSEPHDVRMTHAL 183
Query 185 TPERGLIAL 193
TP++GL+AL
Sbjct 184 TPQKGLVAL 192
>gi|108801255|ref|YP_641452.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. MCS]
gi|119870406|ref|YP_940358.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. KMS]
gi|108771674|gb|ABG10396.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. MCS]
gi|119696495|gb|ABL93568.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. KMS]
Length=197
Score = 190 bits (483), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 115/193 (60%), Positives = 133/193 (69%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +KS +R Q+L ARR+V + + EA L HL + TVCAYVP+G EPGS+
Sbjct 1 MTSPTKSEMRAQVLQARRKVTPETQEREAAALAAHLAEIAAPGRTVCAYVPIGSEPGSLA 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD LL R RVLLPVAR +P PLRWGEYR G LA A++GL EP PWL A+A+
Sbjct 61 MLDELLARGARVLLPVARHDEAGVPAPLRWGEYRPGRLADAQFGLREPAPPWLTADAVAE 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A +VLVPALAVDR GVRLGRG GFYDRSL D A LVAVVR E+VD +P E HDV M
Sbjct 121 ADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAALLVAVVRDEEVVDRVPGEAHDVRM 180
Query 181 THALTPERGLIAL 193
THALTP GL+AL
Sbjct 181 THALTPGCGLVAL 193
>gi|126437234|ref|YP_001072925.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. JLS]
gi|126237034|gb|ABO00435.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium sp. JLS]
Length=197
Score = 187 bits (474), Expect = 8e-46, Method: Compositional matrix adjust.
Identities = 114/193 (60%), Positives = 132/193 (69%), Gaps = 0/193 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +KS +R Q+L ARR+V + + EA L HL + TVCAYVP+G EPGS+
Sbjct 1 MTSPTKSEMRAQVLQARRKVTPEAQEREAAALAAHLAGIAAPGRTVCAYVPIGSEPGSLA 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD LL R RVLLPVAR +P PLRWGEYR G L A++GL EP PWL A+A+
Sbjct 61 MLDELLARGARVLLPVARHDEARVPTPLRWGEYRPGRLVDAQFGLREPAPPWLTADAVAE 120
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM 180
A +VLVPALAVDR GVRLGRG GFYDRSL D A LVAVVR E+VD +P E HDV M
Sbjct 121 ADVVLVPALAVDRCGVRLGRGAGFYDRSLGRADSAAMLVAVVRDEEVVDRVPGEAHDVRM 180
Query 181 THALTPERGLIAL 193
THALTP GL+AL
Sbjct 181 THALTPGCGLVAL 193
>gi|254773981|ref|ZP_05215497.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium avium
subsp. avium ATCC 25291]
Length=206
Score = 186 bits (472), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 111/140 (80%), Positives = 120/140 (86%), Gaps = 0/140 (0%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
MA K+ALR++LLAARRRVADDVRAAEARMLR LE MVTS STVCAYVPVG EPGS+E
Sbjct 1 MATTGKAALRERLLAARRRVADDVRAAEARMLREQLEFMVTSGSTVCAYVPVGAEPGSVE 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ 120
MLD+LLRRAGRVLLPVARTA D PLPL WGEYR G L RWGLLEP +PWLP +ALA
Sbjct 61 MLDMLLRRAGRVLLPVARTAADDTPLPLCWGEYRPGTLTTGRWGLLEPAQPWLPASALAD 120
Query 121 ASLVLVPALAVDRQGVRLGR 140
A+LVLVPALAVDR+GVRLGR
Sbjct 121 AALVLVPALAVDRRGVRLGR 140
>gi|145222486|ref|YP_001133164.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium gilvum PYR-GCK]
gi|145214972|gb|ABP44376.1| 5-formyltetrahydrofolate cyclo-ligase [Mycobacterium gilvum PYR-GCK]
Length=201
Score = 182 bits (462), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 105/190 (56%), Positives = 133/190 (70%), Gaps = 0/190 (0%)
Query 4 ASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLD 63
++KS R +LA RR +++ + E+ +L HL ++ +TVCA++PVG EPGS+ ++D
Sbjct 3 STKSQARAAILAVRRSLSEQTQERESTLLARHLAALIRPGTTVCAHIPVGSEPGSLAIVD 62
Query 64 VLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASL 123
+ RAG VLLPVAR + PLPL+WG Y G L A +GL EP PWLP +A A +
Sbjct 63 DIAGRAGSVLLPVARESDDGTPLPLQWGRYVPGKLVAAPYGLREPEPPWLPPETVATADV 122
Query 124 VLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHA 183
VLVPALAVDR G RLGRG GFYDR+L +P A ++AVVR ELVD LPSEPHDVPMTHA
Sbjct 123 VLVPALAVDRAGSRLGRGAGFYDRTLALVNPAALVIAVVRDDELVDHLPSEPHDVPMTHA 182
Query 184 LTPERGLIAL 193
LTP RGL+ L
Sbjct 183 LTPGRGLVTL 192
>gi|315442933|ref|YP_004075812.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium sp. Spyr1]
gi|315261236|gb|ADT97977.1| 5,10-methenyltetrahydrofolate synthetase [Mycobacterium sp. Spyr1]
Length=196
Score = 182 bits (461), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 105/190 (56%), Positives = 133/190 (70%), Gaps = 0/190 (0%)
Query 4 ASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLD 63
++KS R +LA RR +++ + E+ +L HL ++ +TVCA++PVG EPGS+ ++D
Sbjct 3 STKSQARAAILAVRRSLSEQTQERESTLLARHLAALIRPGTTVCAHIPVGSEPGSLAIVD 62
Query 64 VLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQASL 123
+ RAG VLLPVAR + PLPL+WG Y G L A +GL EP PWLP +A A +
Sbjct 63 DIAGRAGSVLLPVARESDDGTPLPLQWGRYVPGKLVAAPYGLREPEPPWLPPETVATADV 122
Query 124 VLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHA 183
VLVPALAVDR G RLGRG GFYDR+L +P A ++AVVR ELVD LPSEPHDVPMTHA
Sbjct 123 VLVPALAVDRAGSRLGRGAGFYDRTLALVNPAALVIAVVRDDELVDHLPSEPHDVPMTHA 182
Query 184 LTPERGLIAL 193
LTP RGL+ L
Sbjct 183 LTPGRGLVTL 192
>gi|312138620|ref|YP_004005956.1| 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus equi 103S]
gi|311887959|emb|CBH47271.1| putative 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus equi
103S]
Length=199
Score = 159 bits (403), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 92/153 (61%), Positives = 104/153 (68%), Gaps = 6/153 (3%)
Query 42 SDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLAR 100
+ +TVCAYVPVG EPGSIEMLD L RVLLPV G PL W E+ A GLA
Sbjct 49 AGATVCAYVPVGSEPGSIEMLDALRAAGLRVLLPVTGEPG-----PLEWAEFTGAEGLAA 103
Query 101 ARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVA 160
A GL EP P LP +A AS++ VPALAVD +G RLGRG GFYDR+L C DP A LVA
Sbjct 104 AGHGLQEPTGPVLPAGEVASASVIFVPALAVDERGTRLGRGAGFYDRTLGCADPGAALVA 163
Query 161 VVRTVELVDVLPSEPHDVPMTHALTPERGLIAL 193
VVR ELV LP++PHDV M +ALTP RGL+ L
Sbjct 164 VVRDCELVPTLPADPHDVRMHYALTPGRGLVRL 196
>gi|226307877|ref|YP_002767837.1| hypothetical protein RER_43900 [Rhodococcus erythropolis PR4]
gi|226186994|dbj|BAH35098.1| conserved hypothetical protein [Rhodococcus erythropolis PR4]
Length=192
Score = 157 bits (397), Expect = 8e-37, Method: Compositional matrix adjust.
Identities = 93/194 (48%), Positives = 116/194 (60%), Gaps = 6/194 (3%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K+ R LAAR V++ R E L H+ ++ STVCAYVP EPGS +
Sbjct 1 MTPQTKAQWRQIALAARDAVSEHTRNTETAALITHIRSVIVDGSTVCAYVPTRTEPGSTD 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLARARWGLLEPPEPWLPEAALA 119
+LD + A RVLLP+ G PL W EY A GL A++G+ EP P LP AL+
Sbjct 61 LLDAVAEIAQRVLLPITGEPG-----PLSWVEYSGADGLRPAKYGIREPVGPVLPPEALS 115
Query 120 QASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVP 179
+LVPALAVD +G RLGRG GFYDR+L P RLVA+VR ELV+ LP++ HD+P
Sbjct 116 DVECMLVPALAVDLRGTRLGRGAGFYDRTLGSVGPQTRLVAIVRDSELVEALPADDHDIP 175
Query 180 MTHALTPERGLIAL 193
M ALTP GL L
Sbjct 176 MGWALTPRGGLTQL 189
>gi|111022597|ref|YP_705569.1| hypothetical protein RHA1_ro05631 [Rhodococcus jostii RHA1]
gi|110822127|gb|ABG97411.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=192
Score = 156 bits (395), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 97/195 (50%), Positives = 119/195 (62%), Gaps = 8/195 (4%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K R +L+ RR + ++R AE R L + + + STVCAYVP EPGS++
Sbjct 1 MHARTKDEWRQLVLSGRRALTPELRTAEDRALVALVTQGIADGSTVCAYVPTALEPGSLD 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLARARWGLLEPPEP-WLPEAAL 118
LD L + AGRVL+PV R G PL W E+ A GLA A +GL EP P W P+ +
Sbjct 61 FLDALRQVAGRVLVPVTRDPG-----PLHWSEFTGADGLADASYGLREPTGPVWEPDE-I 114
Query 119 AQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDV 178
A + VPALAVDR+GVRLGRG GFYDRSL ARL+ VVR ELV LP +PHDV
Sbjct 115 RSAGTIFVPALAVDRRGVRLGRGAGFYDRSLGLASSDARLITVVRDEELVSELPEDPHDV 174
Query 179 PMTHALTPERGLIAL 193
M ALTP GL+ L
Sbjct 175 RMGWALTPRSGLVPL 189
>gi|229495035|ref|ZP_04388781.1| 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus erythropolis
SK121]
gi|229317966|gb|EEN83841.1| 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus erythropolis
SK121]
Length=196
Score = 156 bits (395), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 92/194 (48%), Positives = 115/194 (60%), Gaps = 6/194 (3%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K+ R LAAR V++ R E L H+ ++ STVCAYVP EPGS +
Sbjct 1 MTPQTKAQWRQIALAARDAVSEHTRNTETAALITHIRSVIVDGSTVCAYVPTRTEPGSTD 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLARARWGLLEPPEPWLPEAALA 119
+LD + A RVLLP+ G PL W EY A GL A++G+ EP P LP L+
Sbjct 61 LLDAVAEIAQRVLLPITGEPG-----PLSWVEYSGADGLRPAKYGIREPVGPVLPPETLS 115
Query 120 QASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVP 179
+LVPALAVD +G RLGRG GFYDR+L P RLVA+VR ELV+ LP++ HD+P
Sbjct 116 DVECMLVPALAVDLRGTRLGRGAGFYDRTLGSVGPQTRLVAIVRDSELVETLPADDHDIP 175
Query 180 MTHALTPERGLIAL 193
M ALTP GL L
Sbjct 176 MGWALTPRGGLTQL 189
>gi|325676313|ref|ZP_08155992.1| 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus equi ATCC
33707]
gi|325552874|gb|EGD22557.1| 5-formyltetrahydrofolate cyclo-ligase [Rhodococcus equi ATCC
33707]
Length=199
Score = 155 bits (391), Expect = 4e-36, Method: Compositional matrix adjust.
Identities = 91/153 (60%), Positives = 103/153 (68%), Gaps = 6/153 (3%)
Query 42 SDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLAR 100
+ +TVCAYVPVG EPGSIEMLD L RVLLPV G PL W E+ A GLA
Sbjct 49 AGATVCAYVPVGSEPGSIEMLDALRAAGLRVLLPVTGEPG-----PLEWAEFTGAEGLAA 103
Query 101 ARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVA 160
A GL EP P LP +A AS++ VPALAVD +G RLGRG GFYDR+L DP A LVA
Sbjct 104 AGHGLQEPFGPVLPAGEVASASVIFVPALAVDERGTRLGRGAGFYDRTLGYADPGAALVA 163
Query 161 VVRTVELVDVLPSEPHDVPMTHALTPERGLIAL 193
VVR ELV LP++PHDV M +ALTP RGL+ L
Sbjct 164 VVRDCELVPTLPADPHDVRMHYALTPGRGLVRL 196
>gi|226365105|ref|YP_002782888.1| 5-formyltetrahydrofolate cyclo-ligase family protein [Rhodococcus
opacus B4]
gi|226243595|dbj|BAH53943.1| putative 5-formyltetrahydrofolate cyclo-ligase family protein
[Rhodococcus opacus B4]
Length=192
Score = 152 bits (384), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 94/194 (49%), Positives = 115/194 (60%), Gaps = 6/194 (3%)
Query 1 MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE 60
M +K R +L RR ++R AE + + + + VT+ STVCAYVP EPGS++
Sbjct 1 MRARTKDEWRQLVLTGRRTRTPELRTAEDQAIVALVTQEVTAGSTVCAYVPTALEPGSVD 60
Query 61 MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-AGGLARARWGLLEPPEPWLPEAALA 119
LD L R AGRVL+PV R G PL W E+ A LA A +GL EP P +
Sbjct 61 FLDALRRVAGRVLVPVTRGPG-----PLYWSEFTGADSLAAASYGLREPTGPVQEPGEIR 115
Query 120 QASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVP 179
A + VPALAVDR+GVRLGRG GFYDR+L ARL+ VVR ELV LP +PHDV
Sbjct 116 SADTIFVPALAVDRRGVRLGRGAGFYDRTLGLAATGARLITVVRDEELVSELPEDPHDVR 175
Query 180 MTHALTPERGLIAL 193
M ALTP GL+ L
Sbjct 176 MGWALTPGSGLVRL 189
>gi|257057233|ref|YP_003135065.1| 5,10-methenyltetrahydrofolate synthetase [Saccharomonospora viridis
DSM 43017]
gi|256587105|gb|ACU98238.1| 5,10-methenyltetrahydrofolate synthetase [Saccharomonospora viridis
DSM 43017]
Length=223
Score = 141 bits (356), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 90/158 (57%), Positives = 100/158 (64%), Gaps = 12/158 (7%)
Query 45 TVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYR-----AGGLA 99
TVC YVP G EPGS EMLDVL R VLLPV T G PL W EY AGG+
Sbjct 37 TVCGYVPFGVEPGSPEMLDVLRDRGRTVLLPVIPTERG----PLDWAEYTGPSSLAGGVF 92
Query 100 RARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLV 159
+LEP P L A+A+A +VLVPALAVDR+G RLG+G G+YDRSL P AR V
Sbjct 93 PQ---VLEPTGPRLGPNAIAEAEVVLVPALAVDRRGARLGKGAGYYDRSLPLASPGARFV 149
Query 160 AVVRTVELVDVLPSEPHDVPMTHALTPERGLIALPCGE 197
AVVR E VD LP+EPHDV M LTP RG+I LP E
Sbjct 150 AVVRDPEFVDRLPAEPHDVRMHAVLTPGRGVIDLPDSE 187
>gi|169628180|ref|YP_001701829.1| 5-formyltetrahydrofolate cyclo-ligase-like protein [Mycobacterium
abscessus ATCC 19977]
gi|169240147|emb|CAM61175.1| Hypothetical 5-formyltetrahydrofolate cyclo-ligase-related protein
[Mycobacterium abscessus]
Length=187
Score = 140 bits (353), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 90/184 (49%), Positives = 113/184 (62%), Gaps = 2/184 (1%)
Query 14 LAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVL 73
+ ARR ++ R + L H+ V+ S + AY+PVG EPGS+ MLD LL R R+L
Sbjct 1 MQARRAISPAEREKQNDALAAHVLTAVSGLSVIAAYLPVGSEPGSVRMLDALLDRGVRIL 60
Query 74 LPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEP-WLPEAALAQASLVLVPALAVD 132
LP+AR +P+ LRWG Y L A +GL EP P AALA+A LVLVPALAVD
Sbjct 61 LPIARNDEAGIPMALRWGYYAREELVDAPFGLREPANPVAGSAAALAEAQLVLVPALAVD 120
Query 133 RQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTHALTPERGLIA 192
+QG RLGRG GFYDRSL LV + E+ D LP+ PHDVP+THA+T + GL+
Sbjct 121 KQGNRLGRGAGFYDRSLGFAARATPLVTPLFVGEIRDELPAGPHDVPITHAITAD-GLVT 179
Query 193 LPCG 196
L G
Sbjct 180 LGAG 183
>gi|300790120|ref|YP_003770411.1| 5-formyltetrahydrofolate cyclo-ligase [Amycolatopsis mediterranei
U32]
gi|299799634|gb|ADJ50009.1| 5-formyltetrahydrofolate cyclo-ligase [Amycolatopsis mediterranei
U32]
gi|340531800|gb|AEK47005.1| 5-formyltetrahydrofolate cyclo-ligase [Amycolatopsis mediterranei
S699]
Length=196
Score = 134 bits (338), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 92/193 (48%), Positives = 114/193 (60%), Gaps = 8/193 (4%)
Query 5 SKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLDV 64
SK+ RD++ AR A + A EA L + ++ + +TVCAY+P G EPG+ +D
Sbjct 10 SKAEWRDRVTRARAGQAAESHAREASALVSAVAKV--TANTVCAYLPFGTEPGTTAFVDA 67
Query 65 LLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGG-LARARW-GLLEPPEPWLPEAALAQAS 122
L RVLLPV R+ PL W EY L +R+ G+ EP L A+ A
Sbjct 68 LAAGGARVLLPVIRSRTD----PLDWAEYTGEAELVPSRFRGIREPGGKRLGTEAVGAAE 123
Query 123 LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH 182
LVLVPALAVD +GVRLGRG G YDRSL A L+AVVR ELV+ LP EPHDV MT
Sbjct 124 LVLVPALAVDSRGVRLGRGAGHYDRSLVFAAAGATLLAVVRDEELVERLPGEPHDVRMTG 183
Query 183 ALTPERGLIALPC 195
ALTP RG++ LP
Sbjct 184 ALTPGRGVVELPV 196
>gi|54026928|ref|YP_121170.1| hypothetical protein nfa49540 [Nocardia farcinica IFM 10152]
gi|54018436|dbj|BAD59806.1| hypothetical protein [Nocardia farcinica IFM 10152]
Length=200
Score = 131 bits (330), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 84/161 (53%), Positives = 98/161 (61%), Gaps = 6/161 (3%)
Query 38 RMVTSDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-G 96
R + VCAYVPV GEPGS +L+ L R+LLPV P L W EY
Sbjct 44 RALAVGEWVCAYVPVRGEPGSTALLEELRAAGARILLPVT-----GAPGALDWAEYTGVA 98
Query 97 GLARARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHA 156
GL AR+GLLEP P L +A+A ++LVPALAVDR+GVRLGRG G+YDR+L P A
Sbjct 99 GLRAARFGLLEPAGPVLGAEVVARAEVILVPALAVDRRGVRLGRGAGYYDRTLGSARPGA 158
Query 157 RLVAVVRTVELVDVLPSEPHDVPMTHALTPERGLIALPCGE 197
RLVAVVR E VD LP E HD+ + LTP GL AL E
Sbjct 159 RLVAVVRDEEFVDRLPEEAHDLRVGWVLTPGGGLRALDGSE 199
>gi|343925211|ref|ZP_08764738.1| hypothetical protein GOALK_038_00150 [Gordonia alkanivorans NBRC
16433]
gi|343764808|dbj|GAA11664.1| hypothetical protein GOALK_038_00150 [Gordonia alkanivorans NBRC
16433]
Length=198
Score = 127 bits (320), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 81/152 (54%), Positives = 92/152 (61%), Gaps = 6/152 (3%)
Query 43 DSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARA 101
D TV AYVPVG EPGS MLD LL R VLLPV P PL W Y G L+
Sbjct 51 DVTVAAYVPVGDEPGSTAMLDALLDRGVTVLLPVVPAGE---PAPLDWARYTGPGSLSPG 107
Query 102 RWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAV 161
RWGLLEP L AA+ AS++L+PAL+VD+ GVRLGRG G+YDR+L A LVAV
Sbjct 108 RWGLLEPTTDRLGVAAIRAASVILIPALSVDKTGVRLGRGAGYYDRTLVGL--SAELVAV 165
Query 162 VRTVELVDVLPSEPHDVPMTHALTPERGLIAL 193
V E VD LP+ HDV + ALTP G L
Sbjct 166 VYDEEFVDSLPAGDHDVAVGWALTPGGGFQEL 197
>gi|256374776|ref|YP_003098436.1| 5-formyltetrahydrofolate cyclo-ligase [Actinosynnema mirum DSM
43827]
gi|255919079|gb|ACU34590.1| 5-formyltetrahydrofolate cyclo-ligase [Actinosynnema mirum DSM
43827]
Length=188
Score = 122 bits (307), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 82/157 (53%), Positives = 98/157 (63%), Gaps = 12/157 (7%)
Query 40 VTSDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLA 99
V + TVCAY+ V GEPGS ML+ L RVLLPV G PL W E+ G L
Sbjct 41 VPAGGTVCAYLAVRGEPGSAGMLESLRGAGFRVLLPVVAGVG-----PLEWAEH-TGALR 94
Query 100 RARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHAR-- 157
+GL EP P L A+A A+LVLVPALAVDR GVRLG+G G+YDR+L P AR
Sbjct 95 AGPFGLREPDGPLLGVGAVAGAALVLVPALAVDRAGVRLGQGGGYYDRTL----PLARGP 150
Query 158 LVAVVRTVELVDVLPSEPHDVPMTHALTPERGLIALP 194
+VAVVR E V+ LP+E HD M+ LTP RG++ LP
Sbjct 151 VVAVVRDEEFVESLPAEAHDARMSAVLTPGRGVVRLP 187
>gi|134097379|ref|YP_001103040.1| 5-formyltetrahydrofolate cyclo-ligase [Saccharopolyspora erythraea
NRRL 2338]
gi|133910002|emb|CAM00114.1| 5-formyltetrahydrofolate cyclo-ligase [Saccharopolyspora erythraea
NRRL 2338]
Length=301
Score = 122 bits (306), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 94/191 (50%), Positives = 111/191 (59%), Gaps = 8/191 (4%)
Query 6 KSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTS--DSTVCAYVPVGGEPGSIEMLD 63
K+ R +LL R R+AEA L + R + +TVCAYVPVGGEPGS E+LD
Sbjct 114 KAQWRRKLLDRRGATNGTTRSAEAAALGEAVLRWLDDRPGATVCAYVPVGGEPGSPELLD 173
Query 64 VLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARWGLLEPPEPWLPEAALAQAS 122
L + RVLLPV + PL W Y L A +GLLEP L A+ +A
Sbjct 174 ELRAKGHRVLLPVVVRSS-----PLDWAAYTGPDSLEPAGYGLLEPSGARLGPEAIGEAD 228
Query 123 LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH 182
VLVPALAVDR+GVRLGRG G+YDRSL P A LVAVVR E V+ LP E HDV +
Sbjct 229 AVLVPALAVDRRGVRLGRGAGYYDRSLPMAAPAAALVAVVRDEEFVEELPGEDHDVRVGA 288
Query 183 ALTPERGLIAL 193
LTP G+ AL
Sbjct 289 VLTPGHGVRAL 299
>gi|302530353|ref|ZP_07282695.1| 5-formyltetrahydrofolate cyclo-ligase [Streptomyces sp. AA4]
gi|302439248|gb|EFL11064.1| 5-formyltetrahydrofolate cyclo-ligase [Streptomyces sp. AA4]
Length=199
Score = 121 bits (304), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 84/153 (55%), Positives = 97/153 (64%), Gaps = 8/153 (5%)
Query 45 TVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARW 103
TVCAY+P G EPG I +++ L RVLLPV D P PL W EY G L R
Sbjct 48 TVCAYLPFGTEPGQISLVNALAATGARVLLPVIP----DTPGPLDWSEYTGPGALLPGRL 103
Query 104 -GLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVV 162
G+LEP P L AA+A A ++L+PALAVDR G RLGRG G+YDR+L P VAVV
Sbjct 104 RGVLEPSGPRLGTAAVASAQVLLIPALAVDRHGTRLGRGAGYYDRTLAAA-PDTARVAVV 162
Query 163 RTVELVDVLPSEPHDVPMTHALTPERGLIALPC 195
R E+VD LP+EPHDVPMT LTP GLI LP
Sbjct 163 RAEEVVDRLPAEPHDVPMTAVLTPS-GLIQLPT 194
>gi|291009063|ref|ZP_06567036.1| 5-formyltetrahydrofolate cyclo-ligase [Saccharopolyspora erythraea
NRRL 2338]
Length=198
Score = 121 bits (303), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 94/192 (49%), Positives = 111/192 (58%), Gaps = 8/192 (4%)
Query 5 SKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTS--DSTVCAYVPVGGEPGSIEML 62
K+ R +LL R R+AEA L + R + +TVCAYVPVGGEPGS E+L
Sbjct 10 QKAQWRRKLLDRRGATNGTTRSAEAAALGEAVLRWLDDRPGATVCAYVPVGGEPGSPELL 69
Query 63 DVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARWGLLEPPEPWLPEAALAQA 121
D L + RVLLPV + PL W Y L A +GLLEP L A+ +A
Sbjct 70 DELRAKGHRVLLPVVVRSS-----PLDWAAYTGPDSLEPAGYGLLEPSGARLGPEAIGEA 124
Query 122 SLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMT 181
VLVPALAVDR+GVRLGRG G+YDRSL P A LVAVVR E V+ LP E HDV +
Sbjct 125 DAVLVPALAVDRRGVRLGRGAGYYDRSLPMAAPAAALVAVVRDEEFVEELPGEDHDVRVG 184
Query 182 HALTPERGLIAL 193
LTP G+ AL
Sbjct 185 AVLTPGHGVRAL 196
>gi|262201379|ref|YP_003272587.1| 5-formyltetrahydrofolate cyclo-ligase [Gordonia bronchialis DSM
43247]
gi|262084726|gb|ACY20694.1| 5-formyltetrahydrofolate cyclo-ligase [Gordonia bronchialis DSM
43247]
Length=174
Score = 119 bits (298), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 81/149 (55%), Positives = 92/149 (62%), Gaps = 6/149 (4%)
Query 43 DSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAG-GLARA 101
D TV AYVPVG EPGS+ +LD LL R VL+PV P PL W Y LAR
Sbjct 27 DVTVAAYVPVGSEPGSLAVLDALLDRGVTVLIPVVPPG---EPGPLDWARYHGQESLARG 83
Query 102 RWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAV 161
RWGL EP L A+ ASL+LVPALAVD+ GVRLGRG G+YDR+L A +VAV
Sbjct 84 RWGLWEPTGARLGVEAIRAASLILVPALAVDKSGVRLGRGGGYYDRTLTGL--TADVVAV 141
Query 162 VRTVELVDVLPSEPHDVPMTHALTPERGL 190
V E+VD LPS P DVP+ LTPE G
Sbjct 142 VYDDEIVDSLPSGPLDVPVGWVLTPEGGF 170
>gi|319950607|ref|ZP_08024515.1| hypothetical protein ES5_13518 [Dietzia cinnamea P4]
gi|319435746|gb|EFV90958.1| hypothetical protein ES5_13518 [Dietzia cinnamea P4]
Length=208
Score = 117 bits (294), Expect = 7e-25, Method: Compositional matrix adjust.
Identities = 78/185 (43%), Positives = 103/185 (56%), Gaps = 6/185 (3%)
Query 4 ASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEMLD 63
A K+ LR ++LA R V VR R + HL +VT+ VCAYVP E G + +
Sbjct 17 AVKTRLRREVLARRAAVPAPVRVRRDRAILDHLAGIVTAGMVVCAYVPDDDEAGGRGLPE 76
Query 64 VLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARWGLLEPPEPWLPEAALAQAS 122
L R RVLLPV+ G P+ W Y L R R+G+L P P +A A
Sbjct 77 ELASRGARVLLPVSPARG-----PVEWATYAGPADLVRGRFGILVPSAPPEGPERIADAD 131
Query 123 LVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMTH 182
LVLVPA+AVDR G RLGRG G+YDRSL P RL+A+ T +++ +P+E HD P+
Sbjct 132 LVLVPAVAVDRSGTRLGRGGGYYDRSLALVGPRTRLLALADTENVLEHIPAEAHDRPVHG 191
Query 183 ALTPE 187
+TP+
Sbjct 192 VVTPD 196
>gi|333921215|ref|YP_004494796.1| 5-formyltetrahydrofolate cyclo-ligase [Amycolicicoccus subflavus
DQS3-9A1]
gi|333483436|gb|AEF41996.1| 5-formyltetrahydrofolate cyclo-ligase [Amycolicicoccus subflavus
DQS3-9A1]
Length=225
Score = 117 bits (294), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 85/197 (44%), Positives = 105/197 (54%), Gaps = 13/197 (6%)
Query 5 SKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVT-------SDSTVCAYVPVGGEPG 57
SK R +L R V+ + E+ L H+ R S + AYVP EPG
Sbjct 33 SKDKWRSAVLGERATVSSATASDESGALTEHVVRAFARIAAHSPGGSLIAAYVPARSEPG 92
Query 58 SIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGG-LARARWGLLEPPEPWLPEA 116
SI MLD L RVLLPV TA G+ L W Y L AR+GL EP L
Sbjct 93 SIAMLDGLAACRARVLLPV--TAPGNT---LDWALYDPDQPLVAARYGLQEPGGTRLGMD 147
Query 117 ALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPH 176
AL++A L++VPALAVDRQGVRLGRG G+YDR+L ++A+VR E V LP PH
Sbjct 148 ALSEAELIIVPALAVDRQGVRLGRGAGYYDRALAVSPLQCPVIAIVRDSEFVAELPESPH 207
Query 177 DVPMTHALTPERGLIAL 193
D + +TP+ GLI L
Sbjct 208 DRRVDGVITPDLGLIRL 224
>gi|255325458|ref|ZP_05366562.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium tuberculostearicum
SK141]
gi|255297544|gb|EET76857.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium tuberculostearicum
SK141]
Length=191
Score = 113 bits (283), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 72/189 (39%), Positives = 105/189 (56%), Gaps = 9/189 (4%)
Query 2 AMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEM 61
++ +K+ LR +L+ ARR ++ + A +R HLE +T TV AY P+G EPG +
Sbjct 4 SITAKNELRARLVQARRELSSEDHDAFTAAVRKHLESELTESMTVAAYWPLGSEPGGADF 63
Query 62 LDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAG-GLARARWGLLEPPEPWLPEAALAQ 120
+ L RVLLP++ G L + EYR + + GL EP P + LA+
Sbjct 64 VPWLKAHVSRVLLPISGENG-----TLTFAEYRGKEAMHTSPLGLNEPQGPSFDSSVLAE 118
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHAR--LVAVVRTVELVDVLPSEPHDV 178
LVL PA+AVD +G R+G+G G+YDR+L PH + + A+V E VD LP+E HD
Sbjct 119 CDLVLAPAMAVDAKGNRMGKGGGYYDRALEPL-PHGKPPVFAMVYPSEFVDELPTEDHDR 177
Query 179 PMTHALTPE 187
+ A+T E
Sbjct 178 KVDAAVTAE 186
>gi|311740867|ref|ZP_07714694.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium pseudogenitalium
ATCC 33035]
gi|311304387|gb|EFQ80463.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium pseudogenitalium
ATCC 33035]
Length=214
Score = 113 bits (282), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 71/189 (38%), Positives = 105/189 (56%), Gaps = 9/189 (4%)
Query 2 AMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIEM 61
++ +K+ LR +L+ ARR ++ + A +R HLE +T TV AY P+G EPG +
Sbjct 27 SITAKNELRARLVQARRELSSEDHDAFTAAVRKHLESELTESMTVAAYWPLGSEPGGADF 86
Query 62 LDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAG-GLARARWGLLEPPEPWLPEAALAQ 120
+ L RVLLP++ G L + EYR + + GL EP P + LA+
Sbjct 87 VPWLKSHVSRVLLPISGENGT-----LTFAEYRGKEAMHTSPLGLNEPQGPSFDSSVLAE 141
Query 121 ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHAR--LVAVVRTVELVDVLPSEPHDV 178
LVL PA+AVD +G R+G+G G+YDR+L PH + + A+V E +D LP+E HD
Sbjct 142 CDLVLAPAMAVDAKGNRMGKGGGYYDRALEPL-PHGKPPVFAMVYPSEFLDALPTEDHDR 200
Query 179 PMTHALTPE 187
+ A+T E
Sbjct 201 KVDAAVTAE 209
>gi|296140950|ref|YP_003648193.1| 5-formyltetrahydrofolate cyclo-ligase [Tsukamurella paurometabola
DSM 20162]
gi|296029084|gb|ADG79854.1| 5-formyltetrahydrofolate cyclo-ligase [Tsukamurella paurometabola
DSM 20162]
Length=186
Score = 113 bits (282), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 79/148 (54%), Positives = 89/148 (61%), Gaps = 12/148 (8%)
Query 46 VCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGL 105
V AYVPVG EPGS +L + G +LLPV D P L W YR G LA +GL
Sbjct 50 VAAYVPVGSEPGSTSLLAAI---RGDILLPVTP----DTPGGLDWAVYR-GELAPGPFGL 101
Query 106 LEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTV 165
LEP L AL VL+PAL V R GVRLGRG G+YDRSLR ARL+AVV
Sbjct 102 LEPTGDRLGVDALTSVDTVLLPALGVSRGGVRLGRGAGYYDRSLRG---DARLIAVVYDH 158
Query 166 ELVDVLPSEPHDVPMTHALTPERGLIAL 193
ELVD LP+EP DVP+ ALTP GL+A
Sbjct 159 ELVDELPAEPTDVPVHAALTPS-GLVAF 185
>gi|317507880|ref|ZP_07965578.1| 5-formyltetrahydrofolate cyclo-ligase [Segniliparus rugosus ATCC
BAA-974]
gi|316253809|gb|EFV13181.1| 5-formyltetrahydrofolate cyclo-ligase [Segniliparus rugosus ATCC
BAA-974]
Length=135
Score = 104 bits (260), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 72/141 (52%), Positives = 83/141 (59%), Gaps = 17/141 (12%)
Query 46 VCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGL 105
V +YVP EPG+ ML R RVL+PV G D L W ++R G
Sbjct 2 VSSYVPTRLEPGTERMLAAFAERGSRVLVPV--VVGPDAAL--AWRQWRQDG-------- 49
Query 106 LEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTV 165
P LP ALA+A+LVLVPALAVDR G RLG+G G YDRSLR DP ARLVAVV
Sbjct 50 -----PDLPPEALAEAALVLVPALAVDRFGTRLGQGGGHYDRSLRHADPEARLVAVVDDP 104
Query 166 ELVDVLPSEPHDVPMTHALTP 186
E+V+ LP EPHD + ALTP
Sbjct 105 EVVEGLPREPHDRRVGWALTP 125
>gi|300781679|ref|ZP_07091533.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium genitalium
ATCC 33030]
gi|300533386|gb|EFK54447.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium genitalium
ATCC 33030]
Length=194
Score = 103 bits (257), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 68/157 (44%), Positives = 91/157 (58%), Gaps = 7/157 (4%)
Query 32 LRGHLERMVTSDSTVCAYVPVGGEPGSIEMLDVLLRRAGRVLLPVARTAGGDLPLPLRWG 91
+R HL + S + V AY P+ EPG E+ DVL V LPV AG L W
Sbjct 28 VRDHLLTHLRSCARVAAYSPMPTEPGGEELPDVLAATGLEVFLPVTLGAG-----VLEWA 82
Query 92 EYRAGGLAR-ARWGLLEPPEPWLPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLR 150
+ G LAR A +G+ EP P + L+ +V+VPAL VDR+G+RLG+G G+YDR+L
Sbjct 83 LHVPGQLARGAHFGITEPTGERFPSSMLSSCDVVIVPALGVDRRGMRLGQGAGYYDRALV 142
Query 151 CRDPHARLVAVVRTVELVDVLPSEPHDVPMTHALTPE 187
R +A+V E+ DVLPSEPHD P+ A+TP+
Sbjct 143 HAGAVPR-IALVYDDEVHDVLPSEPHDKPVDGAVTPQ 178
>gi|297563016|ref|YP_003681990.1| 5-formyltetrahydrofolate cyclo-ligase [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296847464|gb|ADH69484.1| 5-formyltetrahydrofolate cyclo-ligase [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=214
Score = 102 bits (255), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 76/195 (39%), Positives = 101/195 (52%), Gaps = 8/195 (4%)
Query 5 SKSALRDQLLAARRRVADDVRAAEARMLRGHLERM--VTSDSTVCAYVPVGGEPGSIEML 62
+K+ LR L RR + RA +R L + + TV Y VGGEP + +++
Sbjct 9 AKAGLRRGFLERRRARGPEERARAGSAVRDALLDVPWLAMGGTVACYYSVGGEPDTRKLV 68
Query 63 DVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARWGLLEPPEPWLPEAALAQA 121
L +R VLLPV G L W + LA A GLLEP ALA+A
Sbjct 69 AALWKRGAYVLLPVFLPGG-----ELDWAAFDGPDSLAPAGHGLLEPVGRRYGPDALARA 123
Query 122 SLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPMT 181
V+ PA+AVDR+G RLGRG G YDR+L + PH +A+V E V+ LP+EPHD P+
Sbjct 124 DAVVCPAVAVDRRGTRLGRGAGCYDRALARKGPHTPAIALVHDEEFVESLPAEPHDRPVD 183
Query 182 HALTPERGLIALPCG 196
+TP G+ L G
Sbjct 184 AVVTPSGGVRVLGAG 198
>gi|326383763|ref|ZP_08205448.1| 5-formyltetrahydrofolate cyclo-ligase [Gordonia neofelifaecis
NRRL B-59395]
gi|326197527|gb|EGD54716.1| 5-formyltetrahydrofolate cyclo-ligase [Gordonia neofelifaecis
NRRL B-59395]
Length=186
Score = 102 bits (254), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 85/188 (46%), Positives = 102/188 (55%), Gaps = 10/188 (5%)
Query 9 LRDQLLAARRRVADDVRAAEARMLRGHLERM---VTSDSTVCAYVPVGGEPGSIEMLDVL 65
+R ++L AR R++ V A L + R+ + TV AYV EPG MLD L
Sbjct 1 MRRRVLEARSRMSPFVLAQCNAELAEWMYRLPLEIDPGGTVAAYVATRAEPGGTAMLDAL 60
Query 66 LRRAGRVLLPVARTAGGDLPLPLRWGEYRA-GGLARARWGLLEPPEPWLPEAALAQASLV 124
L R RVLLP+ P L WGEYR LA RWGLLEP L L A L+
Sbjct 61 LDRDLRVLLPIVPEGE---PARLLWGEYRGEASLAEGRWGLLEPQGYRLDPDVLHDADLI 117
Query 125 LVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDV-LPSEPHDVPMTHA 183
LVPA+A DR G RLGRG G+YDR+L D A +VAVV EL D +P E +DVPM
Sbjct 118 LVPAVAADRTGARLGRGAGYYDRTLASVD--APVVAVVHDDELFDDGVPHEVNDVPMDWV 175
Query 184 LTPERGLI 191
LTP G +
Sbjct 176 LTPGSGFV 183
>gi|312133845|ref|YP_004001184.1| 5-formyltetrahydrofolate cyclo-ligase [Bifidobacterium longum
subsp. longum BBMN68]
gi|311773136|gb|ADQ02624.1| 5-formyltetrahydrofolate cyclo-ligase [Bifidobacterium longum
subsp. longum BBMN68]
Length=246
Score = 100 bits (248), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 83/220 (38%), Positives = 109/220 (50%), Gaps = 33/220 (15%)
Query 6 KSALRDQLLAARRRVADDVRAAEARML-RGHLERMVTSDSTVCAYVPVGGEPGSIEMLDV 64
K+ LR +L+ R+R+ + R A +L R M+ STV AYV +G E + +L
Sbjct 25 KATLRHHILSRRKRIPAEERGAAGELLVRRFPAHMIQDGSTVAAYVSMGSEIETRPLLRW 84
Query 65 LLRRAGRVLLPVARTAGGDLPLPLRW----------------GEYRAGGLARARWGLLEP 108
LL VL+P R G L + W G AG + P
Sbjct 85 LLAHGCHVLVP--RLGSG---LEIGWSVLDSLESLRSMDAVGGANNAGSCSSPSTVHHRP 139
Query 109 PEPW---LPEAALAQASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTV 165
EP LP AL +A LV+ PALAVD QG RLGRG G+YDR+L R P L+AV
Sbjct 140 DEPTGAVLPPEALEKADLVIAPALAVDPQGNRLGRGAGWYDRALARRKPACPLIAVCWPW 199
Query 166 ELVDV-LPSEPHDVPMTHALTPE-------RGLIALPCGE 197
E++D+ LP+EPHDVP LTPE GL++ P G+
Sbjct 200 EVLDIDLPAEPHDVPADGVLTPEGYRRLSSSGLLSWPAGQ 239
Lambda K H
0.323 0.139 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 208621361780
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40