BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1011
Length=306
Score E
Sequences producing significant alignments: (Bits) Value
gi|254231306|ref|ZP_04924633.1| 4-diphosphocytidyl-2-C-methyl-D-... 600 9e-170
gi|308370095|ref|ZP_07420275.2| 4-diphosphocytidyl-2-C-methyl-D-... 598 4e-169
gi|15608151|ref|NP_215527.1| 4-diphosphocytidyl-2-C-methyl-D-ery... 598 4e-169
gi|326904762|gb|EGE51695.1| 4-diphosphocytidyl-2-C-methyl-D-eryt... 595 2e-168
gi|240169905|ref|ZP_04748564.1| 4-diphosphocytidyl-2-C-methyl-D-... 550 1e-154
gi|183984447|ref|YP_001852738.1| 4-diphosphocytidyl-2-C-methyl-D... 547 7e-154
gi|118619727|ref|YP_908059.1| 4-diphosphocytidyl-2-C-methyl-D-er... 546 2e-153
gi|296169880|ref|ZP_06851492.1| 4-diphosphocytidyl-2-C-methyl-D-... 543 1e-152
gi|342861612|ref|ZP_08718258.1| 4-diphosphocytidyl-2-C-methyl-D-... 541 5e-152
gi|15827038|ref|NP_301301.1| 4-diphosphocytidyl-2-C-methyl-D-ery... 523 2e-146
gi|41407074|ref|NP_959910.1| 4-diphosphocytidyl-2-C-methyl-D-ery... 518 4e-145
gi|118465699|ref|YP_880399.1| 4-diphosphocytidyl-2-C-methyl-D-er... 518 4e-145
gi|189045586|sp|A0QBW1.2|ISPE_MYCA1 RecName: Full=4-diphosphocyt... 517 7e-145
gi|336461346|gb|EGO40217.1| 4-diphosphocytidyl-2C-methyl-D-eryth... 515 3e-144
gi|145222524|ref|YP_001133202.1| 4-diphosphocytidyl-2-C-methyl-D... 490 1e-136
gi|120405749|ref|YP_955578.1| 4-diphosphocytidyl-2-C-methyl-D-er... 481 4e-134
gi|118469701|ref|YP_889675.1| 4-diphosphocytidyl-2-C-methyl-D-er... 468 7e-130
gi|169628232|ref|YP_001701881.1| 4-diphosphocytidyl-2-C-methyl-D... 465 4e-129
gi|333989609|ref|YP_004522223.1| 4-diphosphocytidyl-2-C-methyl-D... 461 5e-128
gi|108801226|ref|YP_641423.1| 4-diphosphocytidyl-2-C-methyl-D-er... 448 6e-124
gi|339294014|gb|AEJ46125.1| 4-diphosphocytidyl-2-C-methyl-D-eryt... 443 1e-122
gi|254820387|ref|ZP_05225388.1| 4-diphosphocytidyl-2-C-methyl-D-... 409 4e-112
gi|333921158|ref|YP_004494739.1| 4-diphosphocytidyl-2-C-methyl-D... 388 5e-106
gi|300790055|ref|YP_003770346.1| 4-diphosphocytidyl-2-C-methyl-D... 375 4e-102
gi|340531732|gb|AEK46937.1| 4-diphosphocytidyl-2-C-methyl-D-eryt... 372 4e-101
gi|226365154|ref|YP_002782937.1| 4-diphosphocytidyl-2-C-methyl-D... 365 5e-99
gi|111022649|ref|YP_705621.1| 4-diphosphocytidyl-2-C-methyl-D-er... 363 2e-98
gi|331694708|ref|YP_004330947.1| 4-diphosphocytidyl-2-C-methyl-D... 356 3e-96
gi|226307839|ref|YP_002767799.1| 4-diphosphocytidyl-2-C-methyl-D... 350 1e-94
gi|312138664|ref|YP_004006000.1| 4-(cytidine 5'-diphospho)-2-c-m... 347 2e-93
gi|302530289|ref|ZP_07282631.1| 4-(cytidine 5'-diphospho)-2-C-me... 347 2e-93
gi|54026875|ref|YP_121117.1| 4-diphosphocytidyl-2-C-methyl-D-ery... 345 4e-93
gi|256374798|ref|YP_003098458.1| 4-diphosphocytidyl-2-C-methyl-D... 342 3e-92
gi|134097412|ref|YP_001103073.1| 4-diphosphocytidyl-2-C-methyl-D... 342 5e-92
gi|257057210|ref|YP_003135042.1| 4-diphosphocytidyl-2-C-methyl-D... 340 1e-91
gi|229494957|ref|ZP_04388708.1| 4-(cytidine 5'-diphospho)-2-C-me... 338 6e-91
gi|296140912|ref|YP_003648155.1| 4-diphosphocytidyl-2C-methyl-D-... 338 9e-91
gi|317506337|ref|ZP_07964149.1| 4-(cytidine 5'-diphospho)-2-C-me... 325 6e-87
gi|296393246|ref|YP_003658130.1| 4-diphosphocytidyl-2C-methyl-D-... 318 8e-85
gi|262201478|ref|YP_003272686.1| 4-diphosphocytidyl-2C-methyl-D-... 313 3e-83
gi|343925261|ref|ZP_08764788.1| 4-diphosphocytidyl-2-C-methyl-D-... 301 1e-79
gi|324998155|ref|ZP_08119267.1| 4-diphosphocytidyl-2-C-methyl-D-... 297 1e-78
gi|330465669|ref|YP_004403412.1| 4-diphosphocytidyl-2-C-methyl-D... 287 1e-75
gi|117927391|ref|YP_871942.1| 4-diphosphocytidyl-2-C-methyl-D-er... 286 4e-75
gi|284033599|ref|YP_003383530.1| 4-diphosphocytidyl-2C-methyl-D-... 281 1e-73
gi|258654667|ref|YP_003203823.1| 4-diphosphocytidyl-2C-methyl-D-... 272 5e-71
gi|309812795|ref|ZP_07706533.1| 4-(cytidine 5'-diphospho)-2-C-me... 267 1e-69
gi|326383798|ref|ZP_08205483.1| 4-diphosphocytidyl-2-C-methyl-D-... 265 5e-69
gi|334337965|ref|YP_004543117.1| 4-diphosphocytidyl-2-C-methyl-D... 265 5e-69
gi|84497819|ref|ZP_00996616.1| 4-diphosphocytidyl-2-C-methyl-D-e... 260 2e-67
>gi|254231306|ref|ZP_04924633.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis C]
gi|308231698|ref|ZP_07413484.2| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Mycobacterium
tuberculosis SUMu001]
gi|308378793|ref|ZP_07483915.2| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis SUMu010]
9 more sequence titles
Length=318
Score = 600 bits (1547), Expect = 9e-170, Method: Compositional matrix adjust.
Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG
Sbjct 13 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 72
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 73 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 132
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL
Sbjct 133 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 192
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA
Sbjct 193 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 252
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV
Sbjct 253 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 312
Query 301 SAPTEV 306
SAPTEV
Sbjct 313 SAPTEV 318
>gi|308370095|ref|ZP_07420275.2| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis SUMu002]
gi|308370576|ref|ZP_07422029.2| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Mycobacterium
tuberculosis SUMu003]
gi|308371831|ref|ZP_07426384.2| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis SUMu004]
13 more sequence titles
Length=318
Score = 598 bits (1541), Expect = 4e-169, Method: Compositional matrix adjust.
Identities = 305/306 (99%), Positives = 305/306 (99%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDR EDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG
Sbjct 13 VPTGSVTVRVPGKVNLYLAVGDRHEDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 72
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 73 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 132
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL
Sbjct 133 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 192
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA
Sbjct 193 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 252
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV
Sbjct 253 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 312
Query 301 SAPTEV 306
SAPTEV
Sbjct 313 SAPTEV 318
>gi|15608151|ref|NP_215527.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
tuberculosis H37Rv]
gi|15840439|ref|NP_335476.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
tuberculosis CDC1551]
gi|31792202|ref|NP_854695.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
bovis AF2122/97]
54 more sequence titles
Length=306
Score = 598 bits (1541), Expect = 4e-169, Method: Compositional matrix adjust.
Identities = 305/306 (99%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG
Sbjct 1 MPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL
Sbjct 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA
Sbjct 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV
Sbjct 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
Query 301 SAPTEV 306
SAPTEV
Sbjct 301 SAPTEV 306
>gi|326904762|gb|EGE51695.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis W-148]
Length=306
Score = 595 bits (1535), Expect = 2e-168, Method: Compositional matrix adjust.
Identities = 304/304 (100%), Positives = 304/304 (100%), Gaps = 0/304 (0%)
Query 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62
TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD
Sbjct 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62
Query 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122
QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE
Sbjct 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122
Query 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182
LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS
Sbjct 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182
Query 183 AVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALR 242
AVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALR
Sbjct 183 AVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALR 242
Query 243 AGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA 302
AGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA
Sbjct 243 AGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA 302
Query 303 PTEV 306
PTEV
Sbjct 303 PTEV 306
>gi|240169905|ref|ZP_04748564.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
kansasii ATCC 12478]
Length=320
Score = 550 bits (1416), Expect = 1e-154, Method: Compositional matrix adjust.
Identities = 281/303 (93%), Positives = 289/303 (96%), Gaps = 0/303 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRR DGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG
Sbjct 14 VPTGSVTVRVPGKVNLYLAVGDRRGDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 73
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A +LP DERNLAWQAAELMAEHVGRAPDVSI+I+KSIPVAGGMAGGSADAAAVLVAMN+L
Sbjct 74 AHELPVDERNLAWQAAELMAEHVGRAPDVSILIEKSIPVAGGMAGGSADAAAVLVAMNAL 133
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WEL++PRRDLR+LA RLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVL FA SGL
Sbjct 134 WELSLPRRDLRLLAERLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLTFAHSGLS 193
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AV+ ELDRLREVGDPPRLGEPGPVLAALAAGDP QLAPLLGNEMQAAAVSLDPAL RA
Sbjct 194 TPAVFTELDRLREVGDPPRLGEPGPVLAALAAGDPQQLAPLLGNEMQAAAVSLDPALRRA 253
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLC SA SAIDVGAQLSGAGVCRTVRVATGPVPGARVV
Sbjct 254 LRAGVEAGALAGIVSGSGPTCAFLCASAESAIDVGAQLSGAGVCRTVRVATGPVPGARVV 313
Query 301 SAP 303
AP
Sbjct 314 PAP 316
>gi|183984447|ref|YP_001852738.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE [Mycobacterium
marinum M]
gi|238689228|sp|B2HDJ9.1|ISPE_MYCMM RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|183177773|gb|ACC42883.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE [Mycobacterium
marinum M]
Length=307
Score = 547 bits (1410), Expect = 7e-154, Method: Compositional matrix adjust.
Identities = 276/303 (92%), Positives = 289/303 (96%), Gaps = 0/303 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGS TVRVPGKVNLYLAVGDRR+DGYHELTTVFHAVSLVDEVTVRNAD+LSLE+VGEG
Sbjct 1 MPTGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTD+RNLAWQAAELMAEHVGRAPDVSI IDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ADRLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELN+PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFA SGL
Sbjct 121 WELNLPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLS 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AV+ ELDRLR+VG PPRL EPGPVLAALAAGDP+QLAPLLGNEMQAAAVSLDPAL RA
Sbjct 181 TPAVFTELDRLRDVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRA 240
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLC +A SA+DV AQLSGAGVCRTVR+ATGPVPGARVV
Sbjct 241 LRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVV 300
Query 301 SAP 303
P
Sbjct 301 PTP 303
>gi|118619727|ref|YP_908059.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
ulcerans Agy99]
gi|166216778|sp|A0PW69.1|ISPE_MYCUA RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|118571837|gb|ABL06588.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE [Mycobacterium
ulcerans Agy99]
Length=307
Score = 546 bits (1406), Expect = 2e-153, Method: Compositional matrix adjust.
Identities = 275/303 (91%), Positives = 289/303 (96%), Gaps = 0/303 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGS TVRVPGKVNLYLAVGDRR+DGYHELTTVFHAVSLVDEVTVRNAD+LSLE+VGEG
Sbjct 1 MPTGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTD+RNLAWQAAELMAEHVGRAPDVSI IDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ADKLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELN+PRRDLRMLAA+LGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFA SGL
Sbjct 121 WELNLPRRDLRMLAAQLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLS 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AV+ ELDRLR+VG PPRL EPGPVLAALAAGDP+QLAPLLGNEMQAAAVSLDPAL RA
Sbjct 181 TPAVFTELDRLRDVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRA 240
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLC +A SA+DV AQLSGAGVCRTVR+ATGPVPGARVV
Sbjct 241 LRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVV 300
Query 301 SAP 303
P
Sbjct 301 PTP 303
>gi|296169880|ref|ZP_06851492.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295895436|gb|EFG75138.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=316
Score = 543 bits (1400), Expect = 1e-152, Method: Compositional matrix adjust.
Identities = 278/306 (91%), Positives = 288/306 (95%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVF AVSL+DEVTVRNADVLSLELVGEG
Sbjct 11 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFQAVSLLDEVTVRNADVLSLELVGEG 70
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD LPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 71 ADTLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 130
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFAD LL
Sbjct 131 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELL 190
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T +V+ ELDRLRE GDPPRLG PGPVLAALAAGD +QLA LLGNEMQAAAVSL+P L R
Sbjct 191 TPSVFGELDRLREAGDPPRLGGPGPVLAALAAGDAEQLASLLGNEMQAAAVSLNPKLRRT 250
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG ++SGAGVCRTVRVA+GPV GARVV
Sbjct 251 LRAGVEAGALAGIVSGSGPTCAFLCGSAGAAVDVGTEVSGAGVCRTVRVASGPVAGARVV 310
Query 301 SAPTEV 306
APTEV
Sbjct 311 PAPTEV 316
>gi|342861612|ref|ZP_08718258.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
colombiense CECT 3035]
gi|342130746|gb|EGT84042.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
colombiense CECT 3035]
Length=318
Score = 541 bits (1394), Expect = 5e-152, Method: Compositional matrix adjust.
Identities = 274/306 (90%), Positives = 290/306 (95%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHEL T+F AVSL+DEVTVRNADVLSLE+VGEG
Sbjct 13 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELNTIFQAVSLLDEVTVRNADVLSLEMVGEG 72
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A++LPTDERNLAWQAAELMAEHVGRAPDVSI+IDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 73 AEKLPTDERNLAWQAAELMAEHVGRAPDVSIIIDKSIPVAGGMAGGSADAAAVLVAMNSL 132
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLR LAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADS LL
Sbjct 133 WELNVPRRDLRALAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSELL 192
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AV+ ELDRLRE GDPPRL PGPVLAALAAGD +QLAPLLGNEMQAAAVSL PAL R
Sbjct 193 TPAVFAELDRLREAGDPPRLPAPGPVLAALAAGDAEQLAPLLGNEMQAAAVSLHPALRRT 252
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGALAGIVSGSGPTCAFLC+SA++A+DVG ++SGAGVCRTVRVA+GPV GARVV
Sbjct 253 LRAGVEAGALAGIVSGSGPTCAFLCSSAAAAVDVGTEVSGAGVCRTVRVASGPVAGARVV 312
Query 301 SAPTEV 306
+PTEV
Sbjct 313 PSPTEV 318
>gi|15827038|ref|NP_301301.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
leprae TN]
gi|221229516|ref|YP_002502932.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
leprae Br4923]
gi|20138714|sp|Q9CD51.1|ISPE_MYCLE RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|254806126|sp|B8ZU60.1|ISPE_MYCLB RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|13092585|emb|CAC29750.1| putative isopentenyl monophosphate kinase [Mycobacterium leprae]
gi|219932623|emb|CAR70335.1| putative isopentenyl monophosphate kinase [Mycobacterium leprae
Br4923]
Length=311
Score = 523 bits (1346), Expect = 2e-146, Method: Compositional matrix adjust.
Identities = 264/303 (88%), Positives = 284/303 (94%), Gaps = 0/303 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGSVTV+VPGK+NLYLAVGD ++GYHEL TVFHAVSLVD+VTVRNADVLSL LVGEG
Sbjct 1 MPTGSVTVQVPGKINLYLAVGDCCDNGYHELVTVFHAVSLVDQVTVRNADVLSLGLVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A+ +PTDE N+AW+AAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ANHVPTDEHNIAWRAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WEL++PRRDL MLAA+LGSDVPFALHGGTALGTGRGEELATVLSR TFHWVLAFADS LL
Sbjct 121 WELSLPRRDLCMLAAKLGSDVPFALHGGTALGTGRGEELATVLSRATFHWVLAFADSSLL 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AVY E DRLR+VG+PPRL EPGPVLAAL A DP+QLAPLLGNE+QAAAVSLDPAL A
Sbjct 181 TPAVYTEFDRLRDVGNPPRLAEPGPVLAALVAADPEQLAPLLGNELQAAAVSLDPALRCA 240
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAG+EAGALAGIVSGSGPTCAFLC SA+SAIDVGAQL+GAGVCRTVRVATGPVPGARVV
Sbjct 241 LRAGMEAGALAGIVSGSGPTCAFLCASATSAIDVGAQLAGAGVCRTVRVATGPVPGARVV 300
Query 301 SAP 303
AP
Sbjct 301 HAP 303
>gi|41407074|ref|NP_959910.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
avium subsp. paratuberculosis K-10]
gi|51316296|sp|Q741W1.1|ISPE_MYCPA RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|41395425|gb|AAS03293.1| hypothetical protein MAP_0976 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=316
Score = 518 bits (1335), Expect = 4e-145, Method: Compositional matrix adjust.
Identities = 272/306 (89%), Positives = 287/306 (94%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTT+F AVSL+DEVTVRNADVLSL++VGEG
Sbjct 11 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLDIVGEG 70
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTDERNLAWQAAELMA+HVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 71 ADKLPTDERNLAWQAAELMADHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 130
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFAD LL
Sbjct 131 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELL 190
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T V+ ELDRLR GDPPRL PGPVLAALAAGD DQLAPLLGNEMQAAAVSL+P L R
Sbjct 191 TRKVFAELDRLRRAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAAAVSLNPGLRRT 250
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGV+AGALAGIVSGSGPTCAFLC SA++A+DVG ++SG GVCRTVRVA+GPV GARVV
Sbjct 251 LRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRVASGPVAGARVV 310
Query 301 SAPTEV 306
APTEV
Sbjct 311 PAPTEV 316
>gi|118465699|ref|YP_880399.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
avium 104]
gi|118166986|gb|ABK67883.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Mycobacterium
avium 104]
Length=316
Score = 518 bits (1334), Expect = 4e-145, Method: Compositional matrix adjust.
Identities = 272/306 (89%), Positives = 287/306 (94%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTT+F AVSL+DEVTVRNADVLSL++VGEG
Sbjct 11 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLDIVGEG 70
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 71 ADKLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 130
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAA+LGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFAD LL
Sbjct 131 WELNVPRRDLRMLAAQLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELL 190
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T V+ ELDRLR GDPPRL PGPVLAALAAGD DQLAPLLGNEMQAAAVSL+P L R
Sbjct 191 TRKVFAELDRLRRAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAAAVSLNPGLRRT 250
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGV+AGALAGIVSGSGPTCAFLC SA++A+DVG ++SG GVCRTVRVA+GPV GARVV
Sbjct 251 LRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRVASGPVAGARVV 310
Query 301 SAPTEV 306
APTEV
Sbjct 311 PAPTEV 316
>gi|189045586|sp|A0QBW1.2|ISPE_MYCA1 RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
Length=306
Score = 517 bits (1332), Expect = 7e-145, Method: Compositional matrix adjust.
Identities = 271/306 (89%), Positives = 287/306 (94%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGSVTVRVPGKVNLYLAVGDRREDGYHELTT+F AVSL+DEVTVRNADVLSL++VGEG
Sbjct 1 MPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLDIVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ADKLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAA+LGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFAD LL
Sbjct 121 WELNVPRRDLRMLAAQLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELL 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T V+ ELDRLR GDPPRL PGPVLAALAAGD DQLAPLLGNEMQAAAVSL+P L R
Sbjct 181 TRKVFAELDRLRRAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAAAVSLNPGLRRT 240
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGV+AGALAGIVSGSGPTCAFLC SA++A+DVG ++SG GVCRTVRVA+GPV GARVV
Sbjct 241 LRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRVASGPVAGARVV 300
Query 301 SAPTEV 306
APTEV
Sbjct 301 PAPTEV 306
>gi|336461346|gb|EGO40217.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Mycobacterium
avium subsp. paratuberculosis S397]
Length=316
Score = 515 bits (1327), Expect = 3e-144, Method: Compositional matrix adjust.
Identities = 271/306 (89%), Positives = 286/306 (94%), Gaps = 0/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTT+F AVSL+DEVTVRNADVLSL++VGEG
Sbjct 11 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLDIVGEG 70
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTDERNLAWQAAELMA+HVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 71 ADKLPTDERNLAWQAAELMADHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 130
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVP ALHGGTALGTGRGEELATVLSRNTFHWVLAFAD LL
Sbjct 131 WELNVPRRDLRMLAARLGSDVPLALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELL 190
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T V+ ELDRLR GDPPRL PGPVLAALAAGD DQLAPLLGNEMQAAAVSL+P L R
Sbjct 191 TRKVFAELDRLRRAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAAAVSLNPGLRRT 250
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGV+AGALAGIVSGSGPTCAFLC SA++A+DVG ++SG GVCRTVRVA+GPV GARVV
Sbjct 251 LRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRVASGPVAGARVV 310
Query 301 SAPTEV 306
APTEV
Sbjct 311 PAPTEV 316
>gi|145222524|ref|YP_001133202.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
gilvum PYR-GCK]
gi|315442972|ref|YP_004075851.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. Spyr1]
gi|189045524|sp|A4T6N7.1|ISPE_MYCGI RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|145215010|gb|ABP44414.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Mycobacterium
gilvum PYR-GCK]
gi|315261275|gb|ADT98016.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. Spyr1]
Length=322
Score = 490 bits (1261), Expect = 1e-136, Method: Compositional matrix adjust.
Identities = 250/307 (82%), Positives = 275/307 (90%), Gaps = 3/307 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYL VGDRR+DGYHELTTVFHAVSL+DEVTVR AD LSLE VGEG
Sbjct 13 VPTGSVTVRVPGKVNLYLDVGDRRQDGYHELTTVFHAVSLLDEVTVRTADTLSLEHVGEG 72
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD LPTDERNLAW+AAELMAEHVGRAPDV+I I+K+IPVAGGMAGGSADAAAVLVAMNSL
Sbjct 73 ADSLPTDERNLAWRAAELMAEHVGRAPDVAISIEKTIPVAGGMAGGSADAAAVLVAMNSL 132
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WEL VPRRDL LAA+LGSDVPFALHGGTALGTGRGEELATVL+RNTFHWVLAF+ GL
Sbjct 133 WELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHWVLAFSPGGLS 192
Query 181 TSAVYNELDRLREVGD---PPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPAL 237
T+ V+ E+DRLR D PPRL P PVLAALA+GDP QLAPLLGN++Q AA+SLDPAL
Sbjct 193 TAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQPAALSLDPAL 252
Query 238 ARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGA 297
R LRAG++AGALAG+VSGSGPTCAFLCTSA +A+D+G L+GAGVCRTVRVA+GPV GA
Sbjct 253 RRTLRAGLDAGALAGLVSGSGPTCAFLCTSAGAAVDIGTDLAGAGVCRTVRVASGPVQGA 312
Query 298 RVVSAPT 304
RVV AP+
Sbjct 313 RVVPAPS 319
>gi|120405749|ref|YP_955578.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
vanbaalenii PYR-1]
gi|189045526|sp|A1TEH2.1|ISPE_MYCVP RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|119958567|gb|ABM15572.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
vanbaalenii PYR-1]
Length=322
Score = 481 bits (1239), Expect = 4e-134, Method: Compositional matrix adjust.
Identities = 244/308 (80%), Positives = 274/308 (89%), Gaps = 3/308 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNLYL VGDRR+DGYHELTTVFHAVSL+DEVTVR AD+LSLE+ GEG
Sbjct 13 VPTGSVTVRVPGKVNLYLDVGDRRDDGYHELTTVFHAVSLLDEVTVRTADILSLEMTGEG 72
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A+ LPTDERNLAW+AAELMA+HVGR+PDV+I I+K+IPVAGGMAGGSADAAAVLVAMNSL
Sbjct 73 AESLPTDERNLAWRAAELMADHVGRSPDVAISIEKTIPVAGGMAGGSADAAAVLVAMNSL 132
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WEL VPRRDL LAA+LGSDVPFALHGGTALGTGRGEELATVL+RNTFHWVLAF+ GL
Sbjct 133 WELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHWVLAFSPGGLS 192
Query 181 TSAVYNELDRLREVGD---PPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPAL 237
T+ V+ E+DRLR D PPRL P PVLAALA+GDP QLAPLLGN++Q AA+SLD L
Sbjct 193 TAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQPAALSLDSTL 252
Query 238 ARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGA 297
R LRAGV+AGALAG+VSGSGPTCAFLC SA +A+DVG +L+GAGVCRTVRVA+GPV GA
Sbjct 253 RRTLRAGVDAGALAGVVSGSGPTCAFLCGSAGAAVDVGTELAGAGVCRTVRVASGPVQGA 312
Query 298 RVVSAPTE 305
RVV +P+
Sbjct 313 RVVPSPSN 320
>gi|118469701|ref|YP_889675.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
smegmatis str. MC2 155]
gi|189045525|sp|A0R3D7.1|ISPE_MYCS2 RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|118170988|gb|ABK71884.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Mycobacterium
smegmatis str. MC2 155]
Length=322
Score = 468 bits (1203), Expect = 7e-130, Method: Compositional matrix adjust.
Identities = 242/306 (80%), Positives = 266/306 (87%), Gaps = 2/306 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
V TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEG
Sbjct 15 VTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEG 74
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A+ LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPVAGGMAGGSADAA VLVAMN+L
Sbjct 75 AESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVAGGMAGGSADAAGVLVAMNTL 134
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WEL VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL
Sbjct 135 WELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLS 194
Query 181 TSAVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALA 238
T V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L
Sbjct 195 TPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLR 254
Query 239 RALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGAR 298
R LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA
Sbjct 255 RTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAH 314
Query 299 VVSAPT 304
VV AP+
Sbjct 315 VVPAPS 320
>gi|169628232|ref|YP_001701881.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
abscessus ATCC 19977]
gi|169240199|emb|CAM61227.1| Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
abscessus]
Length=314
Score = 465 bits (1197), Expect = 4e-129, Method: Compositional matrix adjust.
Identities = 234/305 (77%), Positives = 262/305 (86%), Gaps = 0/305 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTG+VTVR PGKVNLYLAVGD R+DGYHELTTVFHAVSL D+VTVR+ADVLS+++VG+G
Sbjct 9 VPTGAVTVRAPGKVNLYLAVGDLRDDGYHELTTVFHAVSLADDVTVRDADVLSIDVVGQG 68
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
+PTDERNLAWQAAEL A+HVGRAPDVSI I+K IPVAGGMAGGSADAAAVLVAMN L
Sbjct 69 EGTVPTDERNLAWQAAELFADHVGRAPDVSIFINKDIPVAGGMAGGSADAAAVLVAMNEL 128
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
W VPRRDL LAA+LGSDVPFALHGGTALGTGRGE+LATVL+RN FHWV AFAD GL
Sbjct 129 WHAGVPRRDLHHLAAQLGSDVPFALHGGTALGTGRGEQLATVLARNVFHWVFAFADGGLA 188
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T V+ E+DRLRE GDPPRL E +L ALAAGD +LAPLLGNE+QAAAVSL+P L R
Sbjct 189 TPQVFKEIDRLRENGDPPRLAEADELLGALAAGDARRLAPLLGNELQAAAVSLNPELRRT 248
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAG AGALAGIVSGSGPTCAFLCTSA A+ V A+L+GAGVCRTVRVA+GPV GA+V+
Sbjct 249 LRAGESAGALAGIVSGSGPTCAFLCTSADDAVQVSAELAGAGVCRTVRVASGPVHGAQVI 308
Query 301 SAPTE 305
++
Sbjct 309 QGRSD 313
>gi|333989609|ref|YP_004522223.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE [Mycobacterium
sp. JDM601]
gi|333485577|gb|AEF34969.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE [Mycobacterium
sp. JDM601]
Length=320
Score = 461 bits (1187), Expect = 5e-128, Method: Compositional matrix adjust.
Identities = 239/300 (80%), Positives = 261/300 (87%), Gaps = 1/300 (0%)
Query 2 PTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGA 61
PTGSVTVR PGK+NL+LAVGDRR+DGYHELTTVFHAVSLVDEVTVR+AD+LSL + GEGA
Sbjct 14 PTGSVTVRAPGKLNLHLAVGDRRDDGYHELTTVFHAVSLVDEVTVRDADLLSLRIAGEGA 73
Query 62 DQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLW 121
D LPTDERNLAWQAAELMAEHVGRAPDV+I IDKSIPVAGGMAGGSADAAAVLV MN LW
Sbjct 74 DVLPTDERNLAWQAAELMAEHVGRAPDVAITIDKSIPVAGGMAGGSADAAAVLVGMNVLW 133
Query 122 ELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLT 181
EL VPRRDL +AARLGSDVPFALHGGTALGTGRGEELATVL+R TFHWVL FAD GL T
Sbjct 134 ELGVPRRDLHAMAARLGSDVPFALHGGTALGTGRGEELATVLTRETFHWVLVFADRGLST 193
Query 182 SAVYNELDRLREVGDP-PRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
AV+ ELDRLR+ G P +GE PVLAALAAGDP +LA LLGN++Q AAV+L+PAL R
Sbjct 194 PAVFAELDRLRDSGRALPEVGESEPVLAALAAGDPQRLAVLLGNDLQTAAVNLNPALRRT 253
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
LRAGVEAGAL+GIV+GSGPTCAFLC SA SA DV +L+ G R VRVA+GPV GARVV
Sbjct 254 LRAGVEAGALSGIVTGSGPTCAFLCASAPSAADVAVELAAVGAGRAVRVASGPVYGARVV 313
>gi|108801226|ref|YP_641423.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. MCS]
gi|119870377|ref|YP_940329.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. KMS]
gi|126437206|ref|YP_001072897.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. JLS]
gi|108771645|gb|ABG10367.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. MCS]
gi|119696466|gb|ABL93539.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
sp. KMS]
gi|126237006|gb|ABO00407.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Mycobacterium
sp. JLS]
Length=322
Score = 448 bits (1152), Expect = 6e-124, Method: Compositional matrix adjust.
Identities = 237/309 (77%), Positives = 266/309 (87%), Gaps = 5/309 (1%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPTGSVTVRVPGKVNL+L VGD R+DGYH+LTTVFHAVSL+DEVTV AD LSL+L GEG
Sbjct 11 VPTGSVTVRVPGKVNLFLGVGDLRDDGYHDLTTVFHAVSLLDEVTVSTADTLSLDLAGEG 70
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A+ LPTD RNLAW+AAELMAEHVGR+PDV+I I+KSIPVAGGMAGGSADAA VLVAMN L
Sbjct 71 AESLPTDRRNLAWKAAELMAEHVGRSPDVAISIEKSIPVAGGMAGGSADAAGVLVAMNHL 130
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WE+ VPRRDL +AA LGSDVPFALHGGTALGTGRGEELATVL+R+TFHWVLAFA GL
Sbjct 131 WEIGVPRRDLHAMAAELGSDVPFALHGGTALGTGRGEELATVLARSTFHWVLAFAYKGLS 190
Query 181 TSAVYNELDRLREV-----GDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDP 235
T V+ ELDRLR +P RLG+P P+LAALA+GD QLAPLLGN++QAAA+SL P
Sbjct 191 TPKVFRELDRLRATAGAARAEPARLGDPEPMLAALASGDARQLAPLLGNDLQAAALSLSP 250
Query 236 ALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVP 295
L R LRAG++AGALA IVSGSGPTCAFLC S+ AIDVGA+L+GAGVCRTVRVA+GPV
Sbjct 251 DLRRTLRAGLDAGALAAIVSGSGPTCAFLCASSPQAIDVGARLAGAGVCRTVRVASGPVQ 310
Query 296 GARVVSAPT 304
GARVV AP+
Sbjct 311 GARVVPAPS 319
>gi|339294014|gb|AEJ46125.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE [Mycobacterium
tuberculosis CCDC5079]
Length=228
Score = 443 bits (1140), Expect = 1e-122, Method: Compositional matrix adjust.
Identities = 228/228 (100%), Positives = 228/228 (100%), Gaps = 0/228 (0%)
Query 79 MAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLG 138
MAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLG
Sbjct 1 MAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLG 60
Query 139 SDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPP 198
SDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPP
Sbjct 61 SDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPP 120
Query 199 RLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSG 258
RLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSG
Sbjct 121 RLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSG 180
Query 259 PTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV 306
PTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV
Sbjct 181 PTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV 228
>gi|254820387|ref|ZP_05225388.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Mycobacterium
intracellulare ATCC 13950]
Length=220
Score = 409 bits (1050), Expect = 4e-112, Method: Compositional matrix adjust.
Identities = 204/220 (93%), Positives = 212/220 (97%), Gaps = 0/220 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+PTGSVTVRVPGKVNLYLAVGDRREDGYHELTT+F AVSL+DEVTVRNADVLSL++VGEG
Sbjct 1 MPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLQIVGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
AD+LPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
Sbjct 61 ADKLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADS LL
Sbjct 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSELL 180
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAP 220
T AV+ ELDRLRE GDPPRL PGPVLAALAAGD +QLAP
Sbjct 181 TPAVFTELDRLREAGDPPRLPAPGPVLAALAAGDAEQLAP 220
>gi|333921158|ref|YP_004494739.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Amycolicicoccus
subflavus DQS3-9A1]
gi|333483379|gb|AEF41939.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Amycolicicoccus
subflavus DQS3-9A1]
Length=322
Score = 388 bits (997), Expect = 5e-106, Method: Compositional matrix adjust.
Identities = 196/295 (67%), Positives = 229/295 (78%), Gaps = 0/295 (0%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
V VR P KVNL+LAVGD R+DGYHELTTVF A+SL DEV V D L++ + GEGA ++P
Sbjct 9 VKVRAPAKVNLHLAVGDLRDDGYHELTTVFQALSLYDEVAVTRGDALTVSVKGEGAREVP 68
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
DE NL W+AA+LMAE GR+P + I I K IPVAGG+AGGSADAAA LVA+N+LW L +
Sbjct 69 LDENNLVWRAAQLMAEKAGRSPRIHIAIRKGIPVAGGLAGGSADAAATLVALNTLWHLEL 128
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R +L LAA LGSDVPF+L GGTA+G GRGE+L VLSR+T+HWVLAFA+ GL T AVY
Sbjct 129 SRGELSDLAAELGSDVPFSLRGGTAMGIGRGEQLLPVLSRSTYHWVLAFANGGLSTPAVY 188
Query 186 NELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGV 245
ELDRLRE G PRLG ++ AL GDPD LAPLLGN++QAAA+SL P L R LRAG
Sbjct 189 KELDRLRESGTRPRLGSADDLMHALTVGDPDALAPLLGNDLQAAAISLKPQLRRTLRAGK 248
Query 246 EAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
+AGALA IVSGSGPTCAFLC A A+ VG ++S GVCRTVR ATGPVPGARV+
Sbjct 249 DAGALAAIVSGSGPTCAFLCRDAEDAVSVGVEVSATGVCRTVRTATGPVPGARVI 303
>gi|300790055|ref|YP_003770346.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Amycolatopsis
mediterranei U32]
gi|299799569|gb|ADJ49944.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Amycolatopsis
mediterranei U32]
Length=320
Score = 375 bits (963), Expect = 4e-102, Method: Compositional matrix adjust.
Identities = 199/290 (69%), Positives = 228/290 (79%), Gaps = 2/290 (0%)
Query 13 KVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLA 72
KVNL+LAV D REDGYHEL TVF A+SL DEVTV + +E+ GEG +PT +NLA
Sbjct 16 KVNLHLAVDDLREDGYHELVTVFQALSLTDEVTVAVTEEPGIEVYGEGEGSVPTGPKNLA 75
Query 73 WQAAELMAEHVGRA--PDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDL 130
W+A E +A HVGRA P V +++ K IPVAGGMAGGSADAAA LV + SLW L+V R +L
Sbjct 76 WRAVEALAGHVGRAGEPKVRVVLRKGIPVAGGMAGGSADAAATLVGLASLWNLDVTRDEL 135
Query 131 RMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDR 190
+AA LGSDVPFAL+GGTALGTGRGE+L VLSR+TFHWVLAFA GL T V+ ELDR
Sbjct 136 AEIAAGLGSDVPFALYGGTALGTGRGEQLVPVLSRHTFHWVLAFAAEGLSTPKVFGELDR 195
Query 191 LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGAL 250
LR G+PPR+G PV+ ALA+GDP QLA LLGN++QAAAVSL P L R LRAGV AGAL
Sbjct 196 LRAAGNPPRIGSHTPVVEALASGDPRQLALLLGNDLQAAAVSLRPDLRRTLRAGVNAGAL 255
Query 251 AGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
AG VSGSGPTCAFLC A SA++V A+LSGAGVCRTVRVA GPVPGARVV
Sbjct 256 AGTVSGSGPTCAFLCEDAQSAVEVAAELSGAGVCRTVRVAHGPVPGARVV 305
>gi|340531732|gb|AEK46937.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Amycolatopsis
mediterranei S699]
Length=304
Score = 372 bits (955), Expect = 4e-101, Method: Compositional matrix adjust.
Identities = 197/289 (69%), Positives = 227/289 (79%), Gaps = 2/289 (0%)
Query 14 VNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLAW 73
+NL+LAV D REDGYHEL TVF A+SL DEVTV + +E+ GEG +PT +NLAW
Sbjct 1 MNLHLAVDDLREDGYHELVTVFQALSLTDEVTVAVTEEPGIEVYGEGEGSVPTGPKNLAW 60
Query 74 QAAELMAEHVGRA--PDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLR 131
+A E +A HVGRA P V +++ K IPVAGGMAGGSADAAA LV + SLW L+V R +L
Sbjct 61 RAVEALAGHVGRAGEPKVRVVLRKGIPVAGGMAGGSADAAATLVGLASLWNLDVTRDELA 120
Query 132 MLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRL 191
+AA LGSDVPFAL+GGTALGTGRGE+L VLSR+TFHWVLAFA GL T V+ ELDRL
Sbjct 121 EIAAGLGSDVPFALYGGTALGTGRGEQLVPVLSRHTFHWVLAFAAEGLSTPKVFGELDRL 180
Query 192 REVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALA 251
R G+PPR+G PV+ ALA+GDP QLA LLGN++QAAAVSL P L R LRAGV AGALA
Sbjct 181 RAAGNPPRIGSHTPVVEALASGDPRQLALLLGNDLQAAAVSLRPDLRRTLRAGVNAGALA 240
Query 252 GIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
G VSGSGPTCAFLC A SA++V A+LSGAGVCRTVRVA GPVPGARVV
Sbjct 241 GTVSGSGPTCAFLCEDAQSAVEVAAELSGAGVCRTVRVAHGPVPGARVV 289
>gi|226365154|ref|YP_002782937.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
opacus B4]
gi|226243644|dbj|BAH53992.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
opacus B4]
Length=311
Score = 365 bits (937), Expect = 5e-99, Method: Compositional matrix adjust.
Identities = 195/295 (67%), Positives = 233/295 (79%), Gaps = 0/295 (0%)
Query 11 PGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERN 70
P KVNL+LAVGD R+DGYHEL TVF A+SL D V+V A+ LS+++ GE A +PTD RN
Sbjct 14 PSKVNLHLAVGDLRDDGYHELKTVFQALSLGDTVSVVPAETLSVKVRGEDARVVPTDSRN 73
Query 71 LAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDL 130
L WQAAE++A GR PDV I IDK IPVAGGMAGGSADAAA LV +N+LW+L++ R +L
Sbjct 74 LVWQAAEMLAAESGRRPDVEIAIDKGIPVAGGMAGGSADAAATLVGLNALWQLDLSREEL 133
Query 131 RMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDR 190
AA+LGSDVPF+LHGGTA+GTGRGE L VLSR+TFHWVLA A GL T V+ ELDR
Sbjct 134 DGFAAKLGSDVPFSLHGGTAVGTGRGERLLPVLSRSTFHWVLALAKGGLSTPTVFRELDR 193
Query 191 LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGAL 250
LR G+PPRLG P ++ AL GD LAPLLGN++Q+AA+SL+P L R LRAGV AGAL
Sbjct 194 LRADGNPPRLGGPEDLMHALTTGDAATLAPLLGNDLQSAALSLNPGLRRTLRAGVAAGAL 253
Query 251 AGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTE 305
AGIVSGSGPTCAFLC A +A+ V A+L+GAGVCRTVRVA+GPVPGAR+++ E
Sbjct 254 AGIVSGSGPTCAFLCADADAAVRVSAELAGAGVCRTVRVASGPVPGARIINDAAE 308
>gi|111022649|ref|YP_705621.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
jostii RHA1]
gi|122955281|sp|Q0S4S3.1|ISPE_RHOSR RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|110822179|gb|ABG97463.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Rhodococcus
jostii RHA1]
Length=311
Score = 363 bits (932), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 194/295 (66%), Positives = 231/295 (79%), Gaps = 0/295 (0%)
Query 11 PGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERN 70
P KVNL+LAVGD R+DGYHEL TVF A+SL D V+V A+ LS+ + GE A +PTD N
Sbjct 14 PSKVNLHLAVGDLRDDGYHELNTVFQALSLSDTVSVAPAETLSVTVRGEDARVVPTDSSN 73
Query 71 LAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDL 130
L WQAAE++A GR PDV I IDK IPVAGGMAGGSADAAA LV +N+LW+L++ R +L
Sbjct 74 LVWQAAEMLAAESGRRPDVEIAIDKGIPVAGGMAGGSADAAATLVGLNALWQLDLSREEL 133
Query 131 RMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDR 190
AA+LGSDVPF+LHGGTA+GTGRGE L VLSR+TFHWVLA A GL T V+ ELDR
Sbjct 134 DGFAAKLGSDVPFSLHGGTAVGTGRGERLLPVLSRSTFHWVLALAKVGLSTPTVFRELDR 193
Query 191 LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGAL 250
LR G+PPRLG P ++ AL GD LAPLLGN++Q+AA+SL+P L R LRAGV AGAL
Sbjct 194 LRADGNPPRLGGPEDLMHALTTGDAATLAPLLGNDLQSAALSLNPGLRRTLRAGVAAGAL 253
Query 251 AGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTE 305
AGIVSGSGPTCAFLC A +A+ V A+L+GAGVCRTVRVA+GPVPGAR+++ E
Sbjct 254 AGIVSGSGPTCAFLCAEADAAVRVSAELAGAGVCRTVRVASGPVPGARIINDAAE 308
>gi|331694708|ref|YP_004330947.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Pseudonocardia
dioxanivorans CB1190]
gi|326949397|gb|AEA23094.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Pseudonocardia
dioxanivorans CB1190]
Length=323
Score = 356 bits (913), Expect = 3e-96, Method: Compositional matrix adjust.
Identities = 190/296 (65%), Positives = 228/296 (78%), Gaps = 1/296 (0%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
VTVRVPGK+NL+LAVGD R+DG+HEL TVFHAVSL DEVTV ++ +E++G+ A ++P
Sbjct 9 VTVRVPGKINLHLAVGDVRDDGFHELVTVFHAVSLFDEVTVTASESPGIEVLGDSAAEVP 68
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
D NLAW+A EL+ HV DV +++ K IPVAGGMAGGSADAA LVA+ +LW+L++
Sbjct 69 ADGTNLAWRAVELLGRHVEHDTDVRVVLRKGIPVAGGMAGGSADAAGTLVALAALWKLDL 128
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R +L +LAA LGSDV FALHGGTALGTGRGE + VL+R+ HWV+A GL T V+
Sbjct 129 TRDELAVLAADLGSDVTFALHGGTALGTGRGERIVPVLARHPQHWVIALHRQGLSTPTVF 188
Query 186 NELDRLREV-GDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAG 244
ELDRLR DP + PVL ALA GDP QLA LGN++QAAAVSL P L R LRAG
Sbjct 189 GELDRLRAASSDPTPVRAVEPVLEALAGGDPRQLALSLGNDLQAAAVSLAPDLRRTLRAG 248
Query 245 VEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
V AGALAG+VSGSGP+CAFLC SA SA++V A+L+GAGVCRTVRVA GPVPGARVV
Sbjct 249 VSAGALAGLVSGSGPSCAFLCDSADSAVEVAAELAGAGVCRTVRVAHGPVPGARVV 304
>gi|226307839|ref|YP_002767799.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
erythropolis PR4]
gi|226186956|dbj|BAH35060.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
erythropolis PR4]
Length=331
Score = 350 bits (899), Expect = 1e-94, Method: Compositional matrix adjust.
Identities = 196/290 (68%), Positives = 232/290 (80%), Gaps = 0/290 (0%)
Query 11 PGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERN 70
P KVNL+LAVGD R+DGYHELTTVF A+SL D VTV AD L++ ++G+ A +PTD N
Sbjct 34 PSKVNLHLAVGDLRDDGYHELTTVFQALSLADTVTVAPADTLTVRVIGDDAAAVPTDRAN 93
Query 71 LAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDL 130
L W+AAE++A G AP+V I+I+K IPVAGGMAGGSADAAA LVA+NSLW+L+ R DL
Sbjct 94 LVWRAAEMLAAEGGVAPNVEIVIEKGIPVAGGMAGGSADAAAALVALNSLWKLDFSRPDL 153
Query 131 RMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDR 190
AARLGSDVPF+LHGGTALGTGRGE+L VL+R TFHWVLA A GL T V+ ELD+
Sbjct 154 DAFAARLGSDVPFSLHGGTALGTGRGEQLVPVLTRRTFHWVLALAKGGLSTPVVFRELDK 213
Query 191 LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGAL 250
LR G P RLG ++ AL GDP LAPLLGN++QAAA+SL+P L R LRAGVEAGAL
Sbjct 214 LRAEGTPNRLGTADELIHALTTGDPHVLAPLLGNDLQAAALSLNPDLRRTLRAGVEAGAL 273
Query 251 AGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
AGIVSGSGPTCAFLC A SA++V A+L+GAGVCRTVRVA+GPVPGAR++
Sbjct 274 AGIVSGSGPTCAFLCADAQSAVEVSAELAGAGVCRTVRVASGPVPGARIL 323
>gi|312138664|ref|YP_004006000.1| 4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinase [Rhodococcus
equi 103S]
gi|325676267|ref|ZP_08155946.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
equi ATCC 33707]
gi|311888003|emb|CBH47315.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Rhodococcus
equi 103S]
gi|325552828|gb|EGD22511.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Rhodococcus
equi ATCC 33707]
Length=311
Score = 347 bits (889), Expect = 2e-93, Method: Compositional matrix adjust.
Identities = 202/300 (68%), Positives = 239/300 (80%), Gaps = 0/300 (0%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
VTVR P KVNL+L+VGD REDGYHEL TVF A+SL D+V+V +D LS+ + GEGA+ +P
Sbjct 9 VTVRAPSKVNLHLSVGDLREDGYHELRTVFQALSLADDVSVIASDALSVRVRGEGAESVP 68
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
TD NL W+AAE++A G APDV I I K IPVAGGMAGGSADAAA LVA+N LW L +
Sbjct 69 TDHTNLVWKAAEMLAAEAGIAPDVEISIVKGIPVAGGMAGGSADAAAALVALNELWRLGL 128
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R L + AARLGSDVPF+LHGGTA+GTGRGE+L VLSR++FHWVLA A GL T V+
Sbjct 129 DRDALSVFAARLGSDVPFSLHGGTAVGTGRGEKLLPVLSRDSFHWVLALAKGGLSTPTVF 188
Query 186 NELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGV 245
ELDRLR GDPPR+G+ ++ ALA+GD + LAPLLGN++QAAA+SL P L R LRAGV
Sbjct 189 RELDRLRVEGDPPRVGDVDDLMHALASGDAEALAPLLGNDLQAAALSLAPDLRRTLRAGV 248
Query 246 EAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTE 305
AGALAGIVSGSGPTCAFLC A +A+ VGA+LSGAGVCRTVRVA+GPVPGARV+ + E
Sbjct 249 TAGALAGIVSGSGPTCAFLCADADAAVAVGAELSGAGVCRTVRVASGPVPGARVIDSEPE 308
>gi|302530289|ref|ZP_07282631.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Streptomyces
sp. AA4]
gi|302439184|gb|EFL11000.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Streptomyces
sp. AA4]
Length=322
Score = 347 bits (889), Expect = 2e-93, Method: Compositional matrix adjust.
Identities = 198/292 (68%), Positives = 229/292 (79%), Gaps = 4/292 (1%)
Query 13 KVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLA 72
KVNL+LAVGD R DG+HEL TVF A+SL DEVTV AD LE+ GEG +PTD NLA
Sbjct 16 KVNLHLAVGDLRADGFHELVTVFQALSLTDEVTVAAADEPGLEVYGEGERTVPTDGANLA 75
Query 73 WQAAELMAEHVGR----APDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRR 128
W+AA +A + GR AP V I++ K IPVAGGMAGGSADAAA LV ++SLW+L+V R
Sbjct 76 WRAARELAAYAGRPDADAPKVRIVLRKGIPVAGGMAGGSADAAAALVGLSSLWKLDVTRD 135
Query 129 DLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNEL 188
+L +A RLGSDVPFAL+GGTALGTGRGE+L VL R+TFHWVLAF + GL T V+ EL
Sbjct 136 ELATIAGRLGSDVPFALYGGTALGTGRGEQLVPVLGRHTFHWVLAFDEEGLSTPKVFGEL 195
Query 189 DRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAG 248
DRLR G PPR+G PV+ ALA+GDP QLA LLGN++QAAAVSL P L R LRAGV AG
Sbjct 196 DRLRADGKPPRIGSHTPVVEALASGDPRQLALLLGNDLQAAAVSLRPGLRRTLRAGVNAG 255
Query 249 ALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
ALAG VSGSGPTCAFLC+ A +A++V A+LSGAGVCRTVRVA GPVPGARVV
Sbjct 256 ALAGCVSGSGPTCAFLCSDAETAVEVAAELSGAGVCRTVRVAHGPVPGARVV 307
>gi|54026875|ref|YP_121117.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Nocardia farcinica
IFM 10152]
gi|81679805|sp|Q5YPY8.1|ISPE_NOCFA RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|54018383|dbj|BAD59753.1| putative 4-diphosphocytidyl-2-C-methyl-D- erythritol kinase [Nocardia
farcinica IFM 10152]
Length=307
Score = 345 bits (886), Expect = 4e-93, Method: Compositional matrix adjust.
Identities = 202/295 (69%), Positives = 237/295 (81%), Gaps = 0/295 (0%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
V VR P KVNL+L VGD R DGYH+LTTVF A+SL D++ + A L++++ GEGA ++P
Sbjct 9 VLVRAPSKVNLHLGVGDLRPDGYHDLTTVFQALSLGDDLRISPASALTVKVNGEGAAEVP 68
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
TD NL W+AA +A VGRAP V I+IDK IPVAGGMAGGSADAAA LV +N LW++ +
Sbjct 69 TDRTNLVWKAAVRLAHLVGRAPLVEIVIDKGIPVAGGMAGGSADAAAALVGLNELWDMGL 128
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R +L LAA LGSDVPFALHGGTALGTGRGE L VLSRNTFHWVLAFA GL T AV+
Sbjct 129 GRDELSALAAELGSDVPFALHGGTALGTGRGERLLPVLSRNTFHWVLAFAKGGLSTPAVF 188
Query 186 NELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGV 245
ELDRLRE GDPPRLG+P ++ ALA+GDP QLAPLLGN++QAAAVSL P L R LRAGV
Sbjct 189 AELDRLREHGDPPRLGDPQALMQALASGDPAQLAPLLGNDLQAAAVSLKPELRRTLRAGV 248
Query 246 EAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
AGALAG+VSGSGPTCAFLC SA +A+ V A+L+GAGV R+VR A+GPVPGARV+
Sbjct 249 TAGALAGLVSGSGPTCAFLCESADAAVAVAAELAGAGVARSVRTASGPVPGARVI 303
>gi|256374798|ref|YP_003098458.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Actinosynnema
mirum DSM 43827]
gi|255919101|gb|ACU34612.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Actinosynnema
mirum DSM 43827]
Length=321
Score = 342 bits (878), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 188/293 (65%), Positives = 227/293 (78%), Gaps = 3/293 (1%)
Query 13 KVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLA 72
KVNL+LAVGD R+DGYH+L T+F A+SL DEVTV +D +E+ GEGA+ +PTD NLA
Sbjct 16 KVNLHLAVGDLRDDGYHDLVTIFQALSLTDEVTVGASDDPGVEVRGEGAESVPTDPSNLA 75
Query 73 WQAAELMAEHVGRAPD---VSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRD 129
W+A ++AEH GR P+ V + I K+IPVAGGMAGGSADAAA LVA+ +LW+L+ R +
Sbjct 76 WKAVRVLAEHTGRDPEDVKVRVGIRKAIPVAGGMAGGSADAAATLVALAALWKLDTTRDE 135
Query 130 LRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELD 189
L LA R+G+DVPFAL+GGTALGT RG+ L VL ++ FHWVLAF GL T V+ ELD
Sbjct 136 LAELAGRIGADVPFALYGGTALGTDRGDRLVPVLGKHPFHWVLAFDKQGLSTPEVFRELD 195
Query 190 RLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGA 249
RLR G+PPR+GE VL L++GDP QLA LLGN++QAAAVSL P L R LRAGV AGA
Sbjct 196 RLRAEGNPPRVGEAEAVLEGLSSGDPRQLALLLGNDLQAAAVSLRPNLRRTLRAGVNAGA 255
Query 250 LAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA 302
LAG+VSGSGPTCAFLC +A+ V A+L+GAGVCRTVRVA GPVPGARVV A
Sbjct 256 LAGMVSGSGPTCAFLCEDGDTAVRVAAELAGAGVCRTVRVAQGPVPGARVVGA 308
>gi|134097412|ref|YP_001103073.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Saccharopolyspora
erythraea NRRL 2338]
gi|291004598|ref|ZP_06562571.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Saccharopolyspora
erythraea NRRL 2338]
gi|189045540|sp|A4F7X3.1|ISPE_SACEN RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
Short=CMK; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase
gi|133910035|emb|CAM00147.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Saccharopolyspora
erythraea NRRL 2338]
Length=318
Score = 342 bits (876), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 204/304 (68%), Positives = 238/304 (79%), Gaps = 4/304 (1%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
VPT +TVRVP KVNL+L+VGD REDGYHEL TVF A+S+ DEVTV AD +E+ GEG
Sbjct 2 VPT-PITVRVPAKVNLHLSVGDTREDGYHELVTVFQALSMTDEVTVHIADEPGIEVRGEG 60
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPD---VSIMIDKSIPVAGGMAGGSADAAAVLVAM 117
AD +PT NLAW+A +AE GR PD V + I+K IPVAGGMAGGSADAAA L+A+
Sbjct 61 ADSVPTGPSNLAWKAVRALAERCGRDPDEPGVRVSINKGIPVAGGMAGGSADAAAALLAL 120
Query 118 NSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADS 177
N LW L + R +L +AA +GSDVPFAL GGTALGTGRGE+L VL+R+TFHWV+A
Sbjct 121 NHLWRLEMGRDELAGIAADIGSDVPFALQGGTALGTGRGEQLIPVLARHTFHWVIALDRR 180
Query 178 GLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPAL 237
GL T V++ELDRLRE P R+GE PVL ALA+GDP QLA LLGN++QAAAVSL P L
Sbjct 181 GLETPGVFSELDRLREESRPNRVGEVEPVLEALASGDPRQLALLLGNDLQAAAVSLRPGL 240
Query 238 ARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGA 297
R LRAGV+AGALAGIVSGSGPTCAFLCT A +A+ V A+LSGAGVCRTVRVA GPVPGA
Sbjct 241 RRTLRAGVQAGALAGIVSGSGPTCAFLCTDADAAVRVAAELSGAGVCRTVRVAQGPVPGA 300
Query 298 RVVS 301
R+V+
Sbjct 301 RLVT 304
>gi|257057210|ref|YP_003135042.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Saccharomonospora
viridis DSM 43017]
gi|256587082|gb|ACU98215.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Saccharomonospora
viridis DSM 43017]
Length=308
Score = 340 bits (873), Expect = 1e-91, Method: Compositional matrix adjust.
Identities = 193/290 (67%), Positives = 227/290 (79%), Gaps = 3/290 (1%)
Query 13 KVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLA 72
K+NL+L+VGD R+DGYHELTTVF A+SL DEVT +E+ GEGA +P +E NLA
Sbjct 16 KINLHLSVGDVRDDGYHELTTVFQALSLTDEVTALAGGDSGVEVSGEGARSVPKNEDNLA 75
Query 73 WQAAELMAEHVGR---APDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRD 129
+A +AEHVGR A V ++I K IPVAGGMAGGSADAA L+A + LW L++ R +
Sbjct 76 VRAVRALAEHVGRPERAERVRLVIRKGIPVAGGMAGGSADAAGALLACSILWGLDLHRDE 135
Query 130 LRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELD 189
L +AA LGSDVPFAL+GGTALGTGRGE+L VLSR+TFHWVLAF GL T VY ELD
Sbjct 136 LAEVAATLGSDVPFALYGGTALGTGRGEQLVPVLSRHTFHWVLAFDQRGLSTPKVYGELD 195
Query 190 RLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGA 249
RLRE GDPPR+G P +L ALA+GDP +LAPLLGN++QAAA+SL P L R LRAGV AGA
Sbjct 196 RLREAGDPPRVGAPEALLEALASGDPHRLAPLLGNDLQAAAISLRPGLRRTLRAGVTAGA 255
Query 250 LAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARV 299
LAG+VSGSGPTCAFLC+ A SA+ V A+L+GAGVCRTVRVA GPVPGARV
Sbjct 256 LAGVVSGSGPTCAFLCSDADSALKVAAELAGAGVCRTVRVAHGPVPGARV 305
>gi|229494957|ref|ZP_04388708.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Rhodococcus
erythropolis SK121]
gi|229318181|gb|EEN84051.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Rhodococcus
erythropolis SK121]
Length=315
Score = 338 bits (867), Expect = 6e-91, Method: Compositional matrix adjust.
Identities = 191/290 (66%), Positives = 231/290 (80%), Gaps = 0/290 (0%)
Query 11 PGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERN 70
P KVNL+LAVGD R+DGYHELTTVF A+SL D +TV AD L++ ++G+ A +PTD N
Sbjct 18 PSKVNLHLAVGDLRDDGYHELTTVFQALSLADTLTVTPADTLTVRVIGDDAAAVPTDRTN 77
Query 71 LAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDL 130
L W+AAE++A G AP+V I+I+K IPVAGGMAGGSADAAA LVA+N+LW+L+ R DL
Sbjct 78 LVWRAAEMLAVEGGVAPNVEIVIEKGIPVAGGMAGGSADAAAALVALNALWKLDFSRPDL 137
Query 131 RMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDR 190
AARLGSDVPF+LHGGTALGTGRGE+L VL+R+TFHWVLA A GL T V+ ELD+
Sbjct 138 DAFAARLGSDVPFSLHGGTALGTGRGEQLVPVLTRHTFHWVLALAKGGLSTPVVFRELDK 197
Query 191 LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGAL 250
LR G P R+G ++ AL GD LA LLGN++QAAA+SL+P L R LRAGVEAGAL
Sbjct 198 LRAEGSPKRVGSADALIQALTTGDAHLLASLLGNDLQAAALSLNPDLRRTLRAGVEAGAL 257
Query 251 AGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
AGIVSGSGPTCAFLC A SA++V A+L+GAGVCRTVRVA+GPVPGAR++
Sbjct 258 AGIVSGSGPTCAFLCADAQSAVEVSAELAGAGVCRTVRVASGPVPGARIL 307
>gi|296140912|ref|YP_003648155.1| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Tsukamurella
paurometabola DSM 20162]
gi|296029046|gb|ADG79816.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Tsukamurella
paurometabola DSM 20162]
Length=301
Score = 338 bits (866), Expect = 9e-91, Method: Compositional matrix adjust.
Identities = 195/296 (66%), Positives = 230/296 (78%), Gaps = 0/296 (0%)
Query 5 SVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQL 64
S+TVR P KVNL+L VGD R DG+HEL TVF A+SL DEV++ AD LSL + GEGA +
Sbjct 5 SLTVRAPAKVNLHLGVGDVRPDGFHELQTVFQALSLHDEVSLARADELSLHVSGEGARDV 64
Query 65 PTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELN 124
PTD NLA +A +AE G P V I I K IPVAGGMAGGSADAAA L+ +LW L+
Sbjct 65 PTDSTNLAARAVAALAERYGLDPAVRIEIAKGIPVAGGMAGGSADAAAALLGAATLWHLD 124
Query 125 VPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAV 184
+ R +L +AA LGSDVPF+LHGGTALGTGRGE+L LSR FHW LA A GL T AV
Sbjct 125 LSRSELDEIAATLGSDVPFSLHGGTALGTGRGEQLIPALSRGEFHWTLALAREGLSTPAV 184
Query 185 YNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAG 244
Y ELDRLRE GDPPR G P +LAA+A+GDP++LAPLL N++QAAA+SL P L R LRAG
Sbjct 185 YRELDRLREAGDPPRAGSPDDLLAAVASGDPNRLAPLLANDLQAAALSLQPGLRRTLRAG 244
Query 245 VEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
+EAGALAGIVSGSGPTCAFLC + SA++VG++L+GAGVCRTVRVA+GPVPGA V+
Sbjct 245 MEAGALAGIVSGSGPTCAFLCINGESAVEVGSELAGAGVCRTVRVASGPVPGAEVL 300
>gi|317506337|ref|ZP_07964149.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Segniliparus
rugosus ATCC BAA-974]
gi|316255347|gb|EFV14605.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Segniliparus
rugosus ATCC BAA-974]
Length=311
Score = 325 bits (833), Expect = 6e-87, Method: Compositional matrix adjust.
Identities = 187/300 (63%), Positives = 220/300 (74%), Gaps = 0/300 (0%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
+P SV VR PGK+NLYL VGD REDGYHEL+TVF +VSL DEVT+ L + L G G
Sbjct 12 IPNRSVVVRAPGKLNLYLKVGDLREDGYHELSTVFQSVSLADEVTIAEHHELHVRLRGGG 71
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A +PTD RNLAWQAAEL+AEHVGR P+V I I KSIPVAGGMAGGS DAAAVLV + +L
Sbjct 72 AVGVPTDRRNLAWQAAELLAEHVGRDPNVDIAILKSIPVAGGMAGGSTDAAAVLVGLAAL 131
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
W + R +L LAA LGSDVPF + GGTA+GTGRGE L + L+R T HWVLAF+ GL
Sbjct 132 WGEELEREELLELAAELGSDVPFCVFGGTAIGTGRGELLTSALARATLHWVLAFSGEGLS 191
Query 181 TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
T AVY ELDRLR G P+ + +L AL +GD Q+A LL N++Q AA+SL P L R
Sbjct 192 TPAVYRELDRLRAAGTQPKATDCDELLRALVSGDVSQVAGLLHNDLQPAALSLRPDLRRT 251
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
L AG EAGALAGI++GSGPTC FL A A+D+ AQL+GAGVC++VR A GP GARVV
Sbjct 252 LLAGREAGALAGIIAGSGPTCMFLAEDAHHAVDIAAQLAGAGVCQSVRAAHGPARGARVV 311
>gi|296393246|ref|YP_003658130.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Segniliparus
rotundus DSM 44985]
gi|296180393|gb|ADG97299.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Segniliparus
rotundus DSM 44985]
Length=316
Score = 318 bits (814), Expect = 8e-85, Method: Compositional matrix adjust.
Identities = 189/305 (62%), Positives = 223/305 (74%), Gaps = 5/305 (1%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVG-- 58
+P SV VR PGKVNLYL VGD REDGYHEL T+F +VSLVDEVT+ L + L G
Sbjct 12 IPARSVVVRAPGKVNLYLEVGDVREDGYHELNTIFQSVSLVDEVTLAEHHELQVRLRGGN 71
Query 59 ---EGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLV 115
GAD +PT +RNLAWQAAEL+AE +GR P+V I I KSIPVAGGMAGGS DAAAVLV
Sbjct 72 GHSAGADSVPTGQRNLAWQAAELLAERLGREPNVDIGILKSIPVAGGMAGGSTDAAAVLV 131
Query 116 AMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFA 175
+ +LW + R +L LAA LGSDVPF ++GGTA+G GRGE L + L+R T HWVLAF+
Sbjct 132 GLAALWGEEIERDELLELAAELGSDVPFCVYGGTAVGGGRGELLTSALARATLHWVLAFS 191
Query 176 DSGLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDP 235
GL T AVY ELDRLR G P+ + +L ALA GD Q+A LL N++Q AA++L P
Sbjct 192 TQGLSTPAVYRELDRLRAAGTQPKSTDCDELLRALAFGDVAQIAGLLHNDLQPAALALRP 251
Query 236 ALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVP 295
L R L AG EAGALAGI++GSGPTC FL SA A+DV AQL+GAGVC++VRVA GPV
Sbjct 252 DLRRTLSAGQEAGALAGIIAGSGPTCMFLAESAHHAVDVAAQLAGAGVCQSVRVAHGPVK 311
Query 296 GARVV 300
GARVV
Sbjct 312 GARVV 316
>gi|262201478|ref|YP_003272686.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Gordonia bronchialis
DSM 43247]
gi|262084825|gb|ACY20793.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Gordonia bronchialis
DSM 43247]
Length=315
Score = 313 bits (801), Expect = 3e-83, Method: Compositional matrix adjust.
Identities = 190/307 (62%), Positives = 226/307 (74%), Gaps = 7/307 (2%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
V + SVT R P KVNL+L VG RR DGYH+L TVF A+SL D+V V L++ + GEG
Sbjct 8 VVSDSVTARAPSKVNLHLGVGPRRPDGYHDLVTVFQALSLHDDVRVSPGTDLTVSVRGEG 67
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A +P D NLA +A + +AE GR+P +I IDKSIPVAGGMAGGSADAAA LVA ++
Sbjct 68 ASAVPDDSSNLAARAVQALAEWCGRSPVAAIDIDKSIPVAGGMAGGSADAAAALVAAAAM 127
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
W+L+V R DL +AA LGSDVPFALHG TALGTGRGE+L +VLSR FHWVLA A GL
Sbjct 128 WKLDVDRDDLSDIAAGLGSDVPFALHGATALGTGRGEQLISVLSRGEFHWVLALAREGLS 187
Query 181 TSAVYNELDRLRE------VGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLD 234
T VY ELDRLR+ + D P L P ++ ALAAGDP +APLL N++Q AA+SL
Sbjct 188 TPQVYAELDRLRDNRSDDAMTDDP-LRRPDDLMQALAAGDPRAVAPLLHNDLQPAALSLQ 246
Query 235 PALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPV 294
PAL R LRAGV+AGAL GIVSGSGPTCAFLC SA++V A+LSGAGV R+VR A+GPV
Sbjct 247 PALRRTLRAGVDAGALNGIVSGSGPTCAFLCLDEGSAVNVAAELSGAGVARSVRTASGPV 306
Query 295 PGARVVS 301
PG RV+S
Sbjct 307 PGTRVIS 313
>gi|343925261|ref|ZP_08764788.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Gordonia alkanivorans
NBRC 16433]
gi|343764858|dbj|GAA11714.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Gordonia alkanivorans
NBRC 16433]
Length=316
Score = 301 bits (770), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 185/306 (61%), Positives = 223/306 (73%), Gaps = 6/306 (1%)
Query 1 VPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG 60
V T SVT R P KVNL+L VG RR+DGYH+L TVF A+SL D++ V A+ LS+ + GEG
Sbjct 8 VVTDSVTARAPSKVNLHLGVGPRRDDGYHDLVTVFQALSLHDDIRVARANELSVTVRGEG 67
Query 61 ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL 120
A +P D NLA +AA+ +A RA V+I I+K+IPVAGGMAGGSADAA LVA+ L
Sbjct 68 AGSVPADASNLAARAAQALAGWADRAGYVAIGIEKTIPVAGGMAGGSADAAGALVALAHL 127
Query 121 WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL 180
W+L++ R +L +AA LGSDVPFALHG TALGTGRGE+L VLSR FHWVLA A GL
Sbjct 128 WKLDISRDELAEIAAGLGSDVPFALHGNTALGTGRGEQLMQVLSRGEFHWVLALAREGLS 187
Query 181 TSAVYNELDRLREV--GDPPRLGE----PGPVLAALAAGDPDQLAPLLGNEMQAAAVSLD 234
T AVY ELDRLR+ GD G+ P ++ ALA+GDP +APLL N++Q AA+SL
Sbjct 188 TPAVYKELDRLRDTRSGDVDEEGDFLRSPDDLMQALASGDPRAVAPLLHNDLQPAALSLQ 247
Query 235 PALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPV 294
P L R LRAGV+AGAL GIVSGSGPTCAFLC SA++V A+LSGAGV R VR A+GP
Sbjct 248 PTLRRTLRAGVDAGALNGIVSGSGPTCAFLCADEQSAVNVAAELSGAGVARAVRTASGPA 307
Query 295 PGARVV 300
PG RV+
Sbjct 308 PGTRVL 313
>gi|324998155|ref|ZP_08119267.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Pseudonocardia
sp. P1]
Length=325
Score = 297 bits (761), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 184/296 (63%), Positives = 223/296 (76%), Gaps = 3/296 (1%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
VTVRVP K+NL+LAVG R DG+H+L TVFHAVSL DEV+V+ AD +LE+ G+G ++P
Sbjct 9 VTVRVPAKINLHLAVGGVRPDGFHDLVTVFHAVSLFDEVSVQPADEPALEVHGDGVAEVP 68
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
D NLAW+A EL+A+ R PDV + + K IPVAGGMAGGSADAA LVA+ +LW + +
Sbjct 69 LDATNLAWRAVELLAQKADRDPDVRVTLRKGIPVAGGMAGGSADAAGALVALAALWRMEL 128
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R +L LAA LGSDV F LHGGTALGTGRGE + VL+R+ HWV+A A GL T AV+
Sbjct 129 GRDELSTLAAELGSDVTFGLHGGTALGTGRGERIIPVLARHRLHWVIALARGGLSTPAVF 188
Query 186 NELDRLREVGDPPRLGEP-GPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAG 244
ELDRLR GD P PVL AL++GDP++LA LGN++QAAAVS+ P L R LRAG
Sbjct 189 GELDRLR--GDGEITERPVEPVLEALSSGDPNRLALNLGNDLQAAAVSMAPDLRRTLRAG 246
Query 245 VEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
V AGALAG+VSGSGPTCAFLC A +A++V +L+G GVCRTVRVA GPV GARVV
Sbjct 247 VNAGALAGLVSGSGPTCAFLCADADAAVEVATELAGMGVCRTVRVAHGPVGGARVV 302
>gi|330465669|ref|YP_004403412.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Verrucosispora
maris AB-18-032]
gi|328808640|gb|AEB42812.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Verrucosispora
maris AB-18-032]
Length=323
Score = 287 bits (735), Expect = 1e-75, Method: Compositional matrix adjust.
Identities = 169/300 (57%), Positives = 206/300 (69%), Gaps = 2/300 (0%)
Query 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62
TG V VRVP KVNL+L VG R DGYHEL TV+HA+S+ DE+T R D L+L + GEG
Sbjct 24 TGPVRVRVPAKVNLHLGVGPLRRDGYHELNTVYHAISIYDELTARRGDTLTLTMEGEGTG 83
Query 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122
+L D+ NL +AA +A + G P + + K IP+AGG+AGGSADAAA LVA ++LW
Sbjct 84 ELALDDSNLVIRAAHALAGYAGVMPHARLHLRKQIPLAGGLAGGSADAAATLVACDALWG 143
Query 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNT-FHWVLAFADSGLLT 181
+ R +L +AA LGSDVPF +HGGTALGTGRGE ++ VL+R T +HWV+A AD GL T
Sbjct 144 TGLSRDELADIAADLGSDVPFLIHGGTALGTGRGEAISPVLARPTSWHWVVAIADGGLST 203
Query 182 SAVYNELDRLREVGDP-PRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240
Y ELDRLRE G P LG +L AL DP LA LGN++Q AA+SL P+LA
Sbjct 204 PQAYRELDRLREAGAAGPALGSTDALLGALRQRDPRVLARTLGNDLQDAALSLRPSLAAT 263
Query 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
L+AG AGALAGIVSGSGPTC FL A+ A V A+L+ A VCR VR A GPV GAR+
Sbjct 264 LKAGEAAGALAGIVSGSGPTCVFLAADAADAERVAAELTAAEVCRHVRTAHGPVHGARIT 323
>gi|117927391|ref|YP_871942.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Acidothermus
cellulolyticus 11B]
gi|117647854|gb|ABK51956.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Acidothermus
cellulolyticus 11B]
Length=332
Score = 286 bits (731), Expect = 4e-75, Method: Compositional matrix adjust.
Identities = 171/305 (57%), Positives = 213/305 (70%), Gaps = 8/305 (2%)
Query 5 SVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQL 64
SVTV+ K+NLYL VG R DGYH+L TVFHAVSL DE+TV ++ LSLE+ GE A+++
Sbjct 24 SVTVQASAKINLYLRVGPLRSDGYHDLATVFHAVSLHDEITVEESEHLSLEICGEQAEKV 83
Query 65 PTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELN 124
P D NLA +AA L+A +GR P V I++ K IPVAGGMAGGSADAAA L+A +LW
Sbjct 84 PLDGDNLAVRAAMLLARRLGREPGVRIVLRKGIPVAGGMAGGSADAAATLIACAALWHAE 143
Query 125 VPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAV 184
+P +L LAA+LGSDVPF + GGTALG GRGE LA VL+ ++WVLA AD GL T V
Sbjct 144 LPHDELMTLAAQLGSDVPFCVVGGTALGHGRGERLAPVLAAGPWYWVLALADGGLSTPQV 203
Query 185 YNELDR--------LREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPA 236
Y E DR LRE GD L P +L+AL GDP +L LL N++Q AAV+L PA
Sbjct 204 YAEFDRRRASGDGELREPGDGEPLDVPAALLSALRDGDPKRLGSLLHNDLQDAAVALRPA 263
Query 237 LARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPG 296
L R L AG++ GAL GIV GSGPTCAFL + +A+D+ A+L+G+G R VR ATGP G
Sbjct 264 LGRVLEAGLDGGALGGIVCGSGPTCAFLVSDQDAAVDLAARLAGSGWVRAVRCATGPAAG 323
Query 297 ARVVS 301
AR+++
Sbjct 324 ARILA 328
>gi|284033599|ref|YP_003383530.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Kribbella flavida
DSM 17836]
gi|283812892|gb|ADB34731.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Kribbella flavida
DSM 17836]
Length=311
Score = 281 bits (718), Expect = 1e-73, Method: Compositional matrix adjust.
Identities = 160/307 (53%), Positives = 205/307 (67%), Gaps = 10/307 (3%)
Query 2 PTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVT--VRNADVLSLELVGE 59
P+ VTVR P K+NL L+VG R DG+H L TV+ AV+L D+VT VR+ +++E+VG+
Sbjct 5 PSAQVTVRSPAKINLGLSVGPPRPDGFHPLATVYQAVALYDDVTATVRDDAEVTVEVVGD 64
Query 60 GADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNS 119
A +PTD+ NLA +AA L+ V + I K+IPVAGGMAGGS DAAA LVA N
Sbjct 65 FAVNVPTDDSNLAVRAARLLQAEYDVEEGVDLSIRKTIPVAGGMAGGSTDAAATLVACNR 124
Query 120 LWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGL 179
LW L + + +L+ LAA LGSDVPF L G TALG GRGE + V+SR TFHWV A AD GL
Sbjct 125 LWGLQLTQSELQHLAAELGSDVPFCLVGHTALGQGRGEHVTEVMSRGTFHWVFAIADGGL 184
Query 180 LTSAVYNELDRLREVGDPPRLGEPGPV----LAALAAGDPDQLAPLLGNEMQAAAVSLDP 235
T VY ELDR+R P R EP V LAAL +G LA + N++QAAA+SL P
Sbjct 185 STPEVYAELDRIR----PLRRVEPPEVRPELLAALLSGRSAALAVAISNDLQAAALSLRP 240
Query 236 ALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVP 295
L L+ G++ GALA ++SGSGPTC FL + A+D+ +L+ +G+CR VR A GPVP
Sbjct 241 ELGDTLQFGLDQGALAAMISGSGPTCLFLAADSRRAVDLAVELAESGLCRMVRQAEGPVP 300
Query 296 GARVVSA 302
GAR++ A
Sbjct 301 GARILPA 307
>gi|258654667|ref|YP_003203823.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Nakamurella
multipartita DSM 44233]
gi|258557892|gb|ACV80834.1| 4-diphosphocytidyl-2C-methyl-D-erythritolkinase [Nakamurella
multipartita DSM 44233]
Length=317
Score = 272 bits (695), Expect = 5e-71, Method: Compositional matrix adjust.
Identities = 171/297 (58%), Positives = 208/297 (71%), Gaps = 3/297 (1%)
Query 5 SVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQL 64
SV VR P K+NLYLAVGD REDGYH+L TVF AV L DE+TVR A ++ D +
Sbjct 17 SVRVRAPAKINLYLAVGDVREDGYHDLVTVFQAVDLADELTVRPARRSAVRTTPP--DGV 74
Query 65 PTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELN 124
P +NLA AA L+A V+I I K IPVAGGMAGGSADAAA LV +LWEL
Sbjct 75 PVGAKNLAGVAARLLATRTKSGGPVAIDIAKQIPVAGGMAGGSADAAAALVGCAALWELR 134
Query 125 VPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAV 184
V R++L + +G+DVPFAL GGTALGTGRG+ L+ V++R HWVLA AD GL T AV
Sbjct 135 VQRQELIEIGREIGADVPFALAGGTALGTGRGDLLSPVMTRARLHWVLAIADHGLSTPAV 194
Query 185 YNELDRLR-EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRA 243
+ ELDRLR + G PP + +LAAL +G+P ++A LGN++QAAA+SL P L R LRA
Sbjct 195 FAELDRLRAQGGGPPPVRPVDTMLAALTSGEPAKIAAALGNDLQAAAISLAPGLRRTLRA 254
Query 244 GVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300
G +AGAL G+VSGSGPT A LC A SA V A+L+G+G CR+VRVA GP PGARV+
Sbjct 255 GEQAGALGGLVSGSGPTVALLCADAESAGAVAAELAGSGTCRSVRVAAGPAPGARVL 311
>gi|309812795|ref|ZP_07706533.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Dermacoccus
sp. Ellin185]
gi|308433212|gb|EFP57106.1| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Dermacoccus
sp. Ellin185]
Length=308
Score = 267 bits (683), Expect = 1e-69, Method: Compositional matrix adjust.
Identities = 156/300 (52%), Positives = 196/300 (66%), Gaps = 6/300 (2%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
V+VRVP KVNL L VG RR DG+H+L T FHAV L DEV V +AD SL + G GAD +P
Sbjct 11 VSVRVPAKVNLELCVGPRRADGFHDLATTFHAVDLFDEVDVTSADEFSLTVTGLGADVVP 70
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
DE NLAW+AA+LMA G +I I K+IPVAGGMAGGSADAAA LVA ++LW L +
Sbjct 71 CDESNLAWRAAQLMATSYGVDGRCAIAIRKAIPVAGGMAGGSADAAATLVACDALWGLGL 130
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
R L LAA+LGSDVPFAL GGTALGTGRGE++ VL+ T+HW+ A GL T AVY
Sbjct 131 SRATLEELAAQLGSDVPFALTGGTALGTGRGEKIVPVLATGTYHWLFALTHEGLSTPAVY 190
Query 186 NELDRLREVGDPPRLGEPGP---VLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALR 242
E DRLRE R+ EP P +LA++ +GD +A + N+++ AA+SL P L +
Sbjct 191 AECDRLRE---GHRVPEPSPSDGLLASVRSGDVHGVAVAMHNDLEPAALSLMPRLRALME 247
Query 243 AGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA 302
G+E GAL +VSGSGPT AFL S A+ + L+ + +A GA++ SA
Sbjct 248 FGLEVGALNAMVSGSGPTVAFLMASRKDAVALRNVLAAGDLADDYVLAASTPHGAQITSA 307
>gi|326383798|ref|ZP_08205483.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Gordonia neofelifaecis
NRRL B-59395]
gi|326197562|gb|EGD54751.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Gordonia neofelifaecis
NRRL B-59395]
Length=306
Score = 265 bits (678), Expect = 5e-69, Method: Compositional matrix adjust.
Identities = 175/304 (58%), Positives = 216/304 (72%), Gaps = 5/304 (1%)
Query 4 GSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQ 63
G T RVP K+NL+L VG R+DG+HEL+T++ A+SL D+VTVR D LS+ + GE Q
Sbjct 2 GGATARVPAKINLHLGVGPLRDDGFHELSTLYCALSLFDDVTVRADDALSVTVRGESRRQ 61
Query 64 LPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWEL 123
+P D NLA +A +A VG P +I IDK+IPVAGGMAGGSADAA LVA LW L
Sbjct 62 VPADATNLAARAVVALARRVGADPHAAITIDKAIPVAGGMAGGSADAAGALVAAARLWRL 121
Query 124 NVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSA 183
++ R DL +AA LGSDVPF++ GG ALGTGRGE+L VL R HWVLA A +GL T
Sbjct 122 DIARDDLLEIAAELGSDVPFSVVGGAALGTGRGEKLLPVLHRGDMHWVLAVAGTGLSTPE 181
Query 184 VYNELDRLREVGD---PPRLG--EPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALA 238
VY E+DRLR GD P G P ++ ALA+GD +APLL N++Q AA+SL P L
Sbjct 182 VYREIDRLRARGDDDQPAAAGTTRPDALMQALASGDVHAVAPLLHNDLQPAALSLQPLLR 241
Query 239 RALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGAR 298
R LRAG EAGALAGIVSGSGPTCAFLC A +A++V A+LSG+GV + VR A+GPV GAR
Sbjct 242 RTLRAGREAGALAGIVSGSGPTCAFLCADADAAVEVAAELSGSGVAKAVRTASGPVAGAR 301
Query 299 VVSA 302
+++A
Sbjct 302 LIAA 305
>gi|334337965|ref|YP_004543117.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Isoptericola
variabilis 225]
gi|334108333|gb|AEG45223.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Isoptericola
variabilis 225]
Length=312
Score = 265 bits (678), Expect = 5e-69, Method: Compositional matrix adjust.
Identities = 152/308 (50%), Positives = 194/308 (63%), Gaps = 12/308 (3%)
Query 2 PTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADV---LSLELVG 58
P SV VR PGKVNL L VG +EDG+H L T+F AV+L +EVT V +S+ + G
Sbjct 9 PQPSVRVRAPGKVNLSLRVGPVQEDGFHPLVTIFQAVALYEEVTATQVPVGAGISIAVDG 68
Query 59 EGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMN 118
AD++P DE NLAW+AAE +A H G PDV++ + K +PVAGGMAGGSADAAA LVA +
Sbjct 69 PQADRVPLDETNLAWRAAEALARHTGVEPDVALHVTKGVPVAGGMAGGSADAAATLVACD 128
Query 119 SLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSG 178
+LWE +PR +L ++AA LGSDVPFAL G TA+GTGRG+ L ++R FHWV A +D G
Sbjct 129 ALWETGLPRAELAVVAAGLGSDVPFALLGHTAVGTGRGDLLTPAMTRGEFHWVFAVSDDG 188
Query 179 LLTSAVYNELDRL-----REVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSL 233
L T VY D L R+V L + P++ AL AGDP L L N+++ AA+SL
Sbjct 189 LSTPEVYRRFDELTAGQARDV----ELADEAPLMHALRAGDPHALGAALHNDLEPAALSL 244
Query 234 DPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGP 293
P L R L E GAL +VSGSGPT A L S A+ + A + G TV T P
Sbjct 245 RPELERTLTLAREGGALGAVVSGSGPTVAALARSRQHALAIAATWTAEGAADTVWCTTAP 304
Query 294 VPGARVVS 301
GAR+++
Sbjct 305 AHGARLLT 312
>gi|84497819|ref|ZP_00996616.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Janibacter
sp. HTCC2649]
gi|84381319|gb|EAP97202.1| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Janibacter
sp. HTCC2649]
Length=312
Score = 260 bits (664), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 164/300 (55%), Positives = 196/300 (66%), Gaps = 4/300 (1%)
Query 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLP 65
VTVRVP KVNL L VG R+DG+H L+TV+ AV+L D+VTV D S + G AD +P
Sbjct 11 VTVRVPAKVNLELLVGPLRDDGFHTLSTVYQAVNLHDDVTVALDDEWSCSVSGPYADIVP 70
Query 66 TDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNV 125
TD NLA +AA L+AE G V I I KSIPVAGGMAGGSADAAA LVA + LW L +
Sbjct 71 TDASNLALRAARLLAEETGVETPVHISIAKSIPVAGGMAGGSADAAATLVACDRLWSLGL 130
Query 126 PRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVY 185
+L AA LGSDVPF + GGTA+G+GRGE LA VL+R ++HWV A +D GL T VY
Sbjct 131 STEELEEYAAELGSDVPFLIRGGTAVGSGRGERLAPVLARGSYHWVFAISDIGLSTPDVY 190
Query 186 NELDRLREVGDPPRLGEPGP---VLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALR 242
E DRLR P P P ++ AL +GDP LAP L N++Q AA+SL P L L
Sbjct 191 AECDRLRGKSKPAD-ASPEPNSQLMIALRSGDPHILAPQLTNDLQDAAISLRPELGELLA 249
Query 243 AGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSA 302
+G+E GAL G+VSGSGPT AFL SAID+ L+ G R VR A GPV GA V+ A
Sbjct 250 SGMEFGALGGVVSGSGPTVAFLVEDVESAIDLTVALTATGAAREVRKAIGPVHGAHVIPA 309
Lambda K H
0.317 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 518193349062
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40