BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1027c

Length=226
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608167|ref|NP_215543.1|  transcriptional regulatory protein ...   454    5e-126
gi|167968526|ref|ZP_02550803.1|  transcriptional regulatory prote...   452    1e-125
gi|289757111|ref|ZP_06516489.1|  transcriptional regulatory prote...   452    2e-125
gi|296169900|ref|ZP_06851512.1|  KDP operon response regulator Kd...   428    3e-118
gi|41407093|ref|NP_959929.1|  KdpE [Mycobacterium avium subsp. pa...   424    6e-117
gi|254820274|ref|ZP_05225275.1|  KDP operon transcriptional regul...   419    2e-115
gi|240169880|ref|ZP_04748539.1|  KDP operon transcriptional regul...   397    7e-109
gi|342861631|ref|ZP_08718277.1|  KDP operon transcriptional regul...   397    7e-109
gi|336461326|gb|EGO40197.1|  response regulator with CheY-like re...   393    1e-107
gi|120405713|ref|YP_955542.1|  two component transcriptional regu...   385    3e-105
gi|333989633|ref|YP_004522247.1|  transcriptional regulator [Myco...   370    7e-101
gi|118472637|ref|YP_889637.1|  KDP operon transcriptional regulat...   366    1e-99 
gi|226307209|ref|YP_002767169.1|  turgor pressure transcriptional...   363    1e-98 
gi|108801194|ref|YP_641391.1|  two component transcriptional regu...   362    2e-98 
gi|229493212|ref|ZP_04387004.1|  KDP operon transcriptional regul...   362    2e-98 
gi|317506419|ref|ZP_07964224.1|  response regulator receiver doma...   358    3e-97 
gi|169630331|ref|YP_001703980.1|  transcriptional regulatory prot...   357    7e-97 
gi|312140452|ref|YP_004007788.1|  two component system response r...   348    5e-94 
gi|183980660|ref|YP_001848951.1|  transcriptional regulatory prot...   347    6e-94 
gi|296393295|ref|YP_003658179.1|  transcriptional regulator [Segn...   345    2e-93 
gi|111018238|ref|YP_701210.1|  response regulator, two-component ...   340    7e-92 
gi|226360365|ref|YP_002778143.1|  turgor pressure transcriptional...   338    2e-91 
gi|302525129|ref|ZP_07277471.1|  phosphate regulon transcriptiona...   333    1e-89 
gi|291007109|ref|ZP_06565082.1|  sensor histidine kinase [Sacchar...   331    5e-89 
gi|134102522|ref|YP_001108183.1|  two-component response regulato...   330    1e-88 
gi|256379954|ref|YP_003103614.1|  winged helix family two compone...   326    1e-87 
gi|326384127|ref|ZP_08205810.1|  response regulator receiver [Gor...   318    5e-85 
gi|289442448|ref|ZP_06432192.1|  transcriptional regulator kdpE [...   317    6e-85 
gi|54023538|ref|YP_117780.1|  putative two-component system respo...   317    9e-85 
gi|300783817|ref|YP_003764108.1|  two-component system response r...   314    6e-84 
gi|333921901|ref|YP_004495482.1|  phosphate regulon transcription...   314    7e-84 
gi|116671596|ref|YP_832529.1|  two component transcriptional regu...   308    3e-82 
gi|262203938|ref|YP_003275146.1|  response regulator receiver [Go...   307    8e-82 
gi|291454638|ref|ZP_06594028.1|  response regulator [Streptomyces...   305    3e-81 
gi|119960910|ref|YP_948727.1|  KDP operon transcriptional regulat...   297    7e-79 
gi|182435453|ref|YP_001823172.1|  putative two-component system r...   293    9e-78 
gi|311896069|dbj|BAJ28477.1|  putative two-component system respo...   291    4e-77 
gi|284034649|ref|YP_003384580.1|  winged helix family two compone...   288    4e-76 
gi|302554679|ref|ZP_07307021.1|  phosphate regulon transcriptiona...   287    7e-76 
gi|297559280|ref|YP_003678254.1|  two component transcriptional r...   287    1e-75 
gi|328885593|emb|CCA58832.1|  DNA-binding response regulator KdpE...   287    1e-75 
gi|297153701|gb|ADI03413.1|  putative two-component system respon...   286    2e-75 
gi|29828937|ref|NP_823571.1|  two-component system response regul...   285    3e-75 
gi|325001104|ref|ZP_08122216.1|  two component transcriptional re...   284    7e-75 
gi|163839669|ref|YP_001624074.1|  two-component response regulato...   284    8e-75 
gi|326443958|ref|ZP_08218692.1|  putative two-component system re...   283    1e-74 
gi|302541993|ref|ZP_07294335.1|  DNA-binding response regulator K...   283    1e-74 
gi|294815609|ref|ZP_06774252.1|  putative two-component system re...   283    2e-74 
gi|337768622|emb|CCB77335.1|  KDP operon transcriptional regulato...   282    2e-74 
gi|297156667|gb|ADI06379.1|  putative two-component system respon...   282    3e-74 


>gi|15608167|ref|NP_215543.1| transcriptional regulatory protein KdpE [Mycobacterium tuberculosis 
H37Rv]
 gi|15840457|ref|NP_335494.1| DNA-binding response regulator KdpE [Mycobacterium tuberculosis 
CDC1551]
 gi|31792218|ref|NP_854711.1| transcriptional regulatory protein KdpE [Mycobacterium bovis 
AF2122/97]
 70 more sequence titles
 Length=226

 Score =  454 bits (1168),  Expect = 5e-126, Method: Compositional matrix adjust.
 Identities = 226/226 (100%), Positives = 226/226 (100%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG
Sbjct  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE
Sbjct  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226


>gi|167968526|ref|ZP_02550803.1| transcriptional regulatory protein kdpE [Mycobacterium tuberculosis 
H37Ra]
Length=226

 Score =  452 bits (1164),  Expect = 1e-125, Method: Compositional matrix adjust.
 Identities = 225/226 (99%), Positives = 226/226 (100%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPD+VILDLGLPDMSG
Sbjct  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDLVILDLGLPDMSG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE
Sbjct  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226


>gi|289757111|ref|ZP_06516489.1| transcriptional regulatory protein [Mycobacterium tuberculosis 
T85]
 gi|294995216|ref|ZP_06800907.1| transcriptional regulator kdpE [Mycobacterium tuberculosis 210]
 gi|289712675|gb|EFD76687.1| transcriptional regulatory protein [Mycobacterium tuberculosis 
T85]
 gi|326904745|gb|EGE51678.1| transcriptional regulator kdpE [Mycobacterium tuberculosis W-148]
 gi|339294029|gb|AEJ46140.1| transcriptional regulatory protein kdpE [Mycobacterium tuberculosis 
CCDC5079]
 gi|339297669|gb|AEJ49779.1| transcriptional regulatory protein kdpE [Mycobacterium tuberculosis 
CCDC5180]
Length=226

 Score =  452 bits (1162),  Expect = 2e-125, Method: Compositional matrix adjust.
 Identities = 225/226 (99%), Positives = 225/226 (99%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMS 
Sbjct  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSS  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE
Sbjct  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226


>gi|296169900|ref|ZP_06851512.1| KDP operon response regulator KdpE [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295895456|gb|EFG75158.1| KDP operon response regulator KdpE [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=226

 Score =  428 bits (1100),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 210/225 (94%), Positives = 219/225 (98%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRINL+VRGY+VITAS+GAGALRAAAEH PDVV+LDLGLPD+SG
Sbjct  1    MTRVLVIDDEPQILRALRINLSVRGYEVITASSGAGALRAAAEHKPDVVVLDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+ELEQPVIETD+FTVDLA KKVIK+GAEVHLTPTEWGMLEML RNRGKLVGR ELLKE
Sbjct  121  AASELEQPVIETDTFTVDLAAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225


>gi|41407093|ref|NP_959929.1| KdpE [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118466690|ref|YP_880417.1| KDP operon transcriptional regulator KdpE [Mycobacterium avium 
104]
 gi|254774017|ref|ZP_05215533.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
avium subsp. avium ATCC 25291]
 gi|41395444|gb|AAS03312.1| KdpE [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118167977|gb|ABK68874.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
avium 104]
Length=226

 Score =  424 bits (1089),  Expect = 6e-117, Method: Compositional matrix adjust.
 Identities = 206/226 (92%), Positives = 219/226 (97%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRINL+VRGY+V+TASTGAGALRAAAEH PDVVILDLGLPD+SG
Sbjct  1    MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALRAAAEHKPDVVILDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+E+EQPV+ET+SFTVDLA KKV K+G+EVHLTPTEWGMLE+L RNRGKLVGR ELLKE
Sbjct  121  AASEMEQPVVETESFTVDLAAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLE+DPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA  226


>gi|254820274|ref|ZP_05225275.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
intracellulare ATCC 13950]
Length=226

 Score =  419 bits (1076),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 205/225 (92%), Positives = 217/225 (97%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRINL+VRGY+V+TAS+GAGALRAAAEH PDVVILDLGLPD+SG
Sbjct  1    MTRVLVIDDEPQILRALRINLSVRGYEVVTASSGAGALRAAAEHKPDVVILDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+E+EQPVIET+SFTVDLA KKV K+G EVHLTPTEWGMLE+L RNRGKLVGR ELLKE
Sbjct  121  AASEVEQPVIETESFTVDLAAKKVSKNGGEVHLTPTEWGMLEVLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYATETHYLRVYLAQLRRKLEDDPS+PKHLLTESGMGYRFE
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSNPKHLLTESGMGYRFE  225


>gi|240169880|ref|ZP_04748539.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
kansasii ATCC 12478]
Length=226

 Score =  397 bits (1020),  Expect = 7e-109, Method: Compositional matrix adjust.
 Identities = 208/226 (93%), Positives = 218/226 (97%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEP ILRALRINLTVRGY+VITASTGAGALRAAAEHPPDVVILDLGLPD+SG
Sbjct  1    MTRVLVIDDEPHILRALRINLTVRGYEVITASTGAGALRAAAEHPPDVVILDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRN 
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+E++QPV+ETD+FTVDLA KKV K+GAEVHLTPTEWGMLE+L RNRGKLVGR ELLKE
Sbjct  121  AASEVDQPVVETDAFTVDLAAKKVTKNGAEVHLTPTEWGMLEVLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226


>gi|342861631|ref|ZP_08718277.1| KDP operon transcriptional regulator KdpE [Mycobacterium colombiense 
CECT 3035]
 gi|342130765|gb|EGT84061.1| KDP operon transcriptional regulator KdpE [Mycobacterium colombiense 
CECT 3035]
Length=226

 Score =  397 bits (1019),  Expect = 7e-109, Method: Compositional matrix adjust.
 Identities = 208/226 (93%), Positives = 218/226 (97%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRINLTVRGY+VITAS+GAGALRAAAEH PDVVILDLGLPD+SG
Sbjct  1    MTRVLVIDDEPQILRALRINLTVRGYEVITASSGAGALRAAAEHKPDVVILDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRN 
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+ELEQPVIET+SFTVDLA KKV K+G+EVHLTPTEWGMLE+L RNRGKLVGR ELLKE
Sbjct  121  AASELEQPVIETESFTVDLAAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYATETHYLRVYLAQLRRKLE+DPSHPKHLLTESGMGYRFEA
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLENDPSHPKHLLTESGMGYRFEA  226


>gi|336461326|gb|EGO40197.1| response regulator with CheY-like receiver domain-containing 
protein [Mycobacterium avium subsp. paratuberculosis S397]
Length=214

 Score =  393 bits (1009),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 191/212 (91%), Positives = 204/212 (97%), Gaps = 0/212 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRINL+VRGY+V+TASTGAGALRAAAEH PDVVILDLGLPD+SG
Sbjct  1    MTRVLVIDDEPQILRALRINLSVRGYEVVTASTGAGALRAAAEHKPDVVILDLGLPDISG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            IDVL GLRGWLTAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRRNT
Sbjct  61   IDVLAGLRGWLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AA+E+EQPV+ET+SFTVDLA KKV K+G+EVHLTPTEWGMLE+L RNRGKLVGR ELLKE
Sbjct  121  AASEMEQPVVETESFTVDLAAKKVTKNGSEVHLTPTEWGMLEVLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPK  212
            VWGPAYATETHYLRVYLAQLRRKLE+DPSHP 
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLENDPSHPN  212


>gi|120405713|ref|YP_955542.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958531|gb|ABM15536.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=230

 Score =  385 bits (988),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 188/224 (84%), Positives = 205/224 (92%), Gaps = 0/224 (0%)

Query  2    TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGI  61
            T VLVIDDEPQILRALRINL+VRGY+V TA++GA ALR AA+H PDVV+LDLGLPDM+GI
Sbjct  6    TRVLVIDDEPQILRALRINLSVRGYEVHTAASGAEALRMAADHKPDVVVLDLGLPDMTGI  65

Query  62   DVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTA  121
            +VL GLRGWL+APVIVLSAR+DS+DKV+ALDAGADDYVTKPFGMDEFLARLRAAVRR   
Sbjct  66   EVLAGLRGWLSAPVIVLSARSDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGAT  125

Query  122  AAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEV  181
            AAE ++PVIET SFTVDLA KKV K G EVHLTPTEWGMLEML R+RGKLVGR ELLKEV
Sbjct  126  AAETDEPVIETSSFTVDLAAKKVTKGGVEVHLTPTEWGMLEMLVRHRGKLVGREELLKEV  185

Query  182  WGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            WGPAYA ETHYLRVYLAQLRRKLEDDPSHP HLLTE+GMGYRF+
Sbjct  186  WGPAYAKETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFQ  229


>gi|333989633|ref|YP_004522247.1| transcriptional regulator [Mycobacterium sp. JDM601]
 gi|333485601|gb|AEF34993.1| transcriptional regulatory protein KdpE [Mycobacterium sp. JDM601]
Length=227

 Score =  370 bits (951),  Expect = 7e-101, Method: Compositional matrix adjust.
 Identities = 190/224 (85%), Positives = 208/224 (93%), Gaps = 0/224 (0%)

Query  2    TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGI  61
            T VLV+DDEPQILRAL+INL+VRGY+V+TA+TGAGALRAAAEH PDVVILDLGLPD+SGI
Sbjct  3    TRVLVVDDEPQILRALKINLSVRGYEVVTAATGAGALRAAAEHRPDVVILDLGLPDISGI  62

Query  62   DVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTA  121
            +VL GLRGWLT PVIVLSARTDS+DKV+ALDAGADDYVTKPFGMDEFLARLRAA RRN  
Sbjct  63   EVLAGLRGWLTVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAARRNAT  122

Query  122  AAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEV  181
            AAE++QP++ET SFTVDLA KKV K+G EVHLTPTEWGMLEML RNRGKLVGR ELL +V
Sbjct  123  AAEIDQPIVETSSFTVDLAAKKVTKNGGEVHLTPTEWGMLEMLVRNRGKLVGRDELLTQV  182

Query  182  WGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            WGPAYA ET YLRVYLAQLRRKLEDDPS+PKHLLTE+GMGYRFE
Sbjct  183  WGPAYAKETQYLRVYLAQLRRKLEDDPSNPKHLLTEAGMGYRFE  226


>gi|118472637|ref|YP_889637.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
smegmatis str. MC2 155]
 gi|118173924|gb|ABK74820.1| KDP operon transcriptional regulatory protein KdpE [Mycobacterium 
smegmatis str. MC2 155]
Length=230

 Score =  366 bits (940),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 192/225 (86%), Positives = 207/225 (92%), Gaps = 1/225 (0%)

Query  2    TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGI  61
            T VLVIDDEPQILRALRINL+VRGY+V TA++GA AL +AA+H PDV++LDLGLPDMSGI
Sbjct  7    TRVLVIDDEPQILRALRINLSVRGYEVRTAASGAEALHSAADHRPDVIVLDLGLPDMSGI  66

Query  62   DVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTA  121
            +VL GLRGWL+APVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAA R   A
Sbjct  67   EVLHGLRGWLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAAR-RAA  125

Query  122  AAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEV  181
              E +QPVIET SFTVDLA KKVIK+GAEVHLTPTEWGMLEML RNRGKLVGR ELL+EV
Sbjct  126  VPETDQPVIETTSFTVDLAAKKVIKNGAEVHLTPTEWGMLEMLVRNRGKLVGREELLREV  185

Query  182  WGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            WGPAYATETHYLRVYLAQLRRKLEDDPSHP HLLTE+GMGYRFEA
Sbjct  186  WGPAYATETHYLRVYLAQLRRKLEDDPSHPVHLLTEAGMGYRFEA  230


>gi|226307209|ref|YP_002767169.1| turgor pressure transcriptional regulator [Rhodococcus erythropolis 
PR4]
 gi|226186326|dbj|BAH34430.1| turgor pressure transcriptional regulator [Rhodococcus erythropolis 
PR4]
Length=226

 Score =  363 bits (932),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 183/224 (82%), Positives = 203/224 (91%), Gaps = 0/224 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            M+ +LV+DDEPQILRALRINLTVRGY V+TASTGAGALRAAAE PPDVVILDLGLPDM G
Sbjct  1    MSRILVVDDEPQILRALRINLTVRGYDVVTASTGAGALRAAAERPPDVVILDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW TAPVIVLSARTDS+DKV+ALDAGADDYVTKPFGMDEFLAR+RAA RR T
Sbjct  61   TEVLAGLRGWCTAPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARVRAAARRGT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            +AA+  +P +ET SFTVDLA K V + G +VHLTPTEWGMLEML RNRGKLVG+ ELL+E
Sbjct  121  SAADTSEPSVETASFTVDLAAKTVSRRGEQVHLTPTEWGMLEMLVRNRGKLVGQKELLRE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRF  224
            VWGPAY TETHYLRVYLAQLRRKLEDDP++PKHL+TE+GMGYRF
Sbjct  181  VWGPAYDTETHYLRVYLAQLRRKLEDDPANPKHLITEAGMGYRF  224


>gi|108801194|ref|YP_641391.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119870326|ref|YP_940278.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|126437173|ref|YP_001072864.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|108771613|gb|ABG10335.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119696415|gb|ABL93488.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
 gi|126236973|gb|ABO00374.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=226

 Score =  362 bits (930),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 185/225 (83%), Positives = 209/225 (93%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRAL+INL+VRGY+V TA+TGA ALR+AA+H PDV++LDLGLPDMSG
Sbjct  1    MTRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            I+VL GLRGWL+APVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRR T
Sbjct  61   IEVLAGLRGWLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRAT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
              ++ ++PV+ T SFTVDLA K+V+K+GAEVHLTPTEWGMLEML R+RGKLVGR ELLKE
Sbjct  121  KESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGMLEMLVRHRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYA ETHYLRVYLAQLRRKLEDDPS P+HLLTE+GMGYRF+
Sbjct  181  VWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQ  225


>gi|229493212|ref|ZP_04387004.1| KDP operon transcriptional regulatory protein KdpE [Rhodococcus 
erythropolis SK121]
 gi|229319943|gb|EEN85772.1| KDP operon transcriptional regulatory protein KdpE [Rhodococcus 
erythropolis SK121]
Length=226

 Score =  362 bits (930),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 181/224 (81%), Positives = 204/224 (92%), Gaps = 0/224 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            M+ +LV+DDEPQILRALRINL+VRGY+V+TASTGAGALRAAAE PPDVV+LDLGLPDM G
Sbjct  1    MSRILVVDDEPQILRALRINLSVRGYEVVTASTGAGALRAAAERPPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW TAPVIVLSARTDS+DKV+ALDAGADDYVTKPFGMDEFLAR+RAA RR T
Sbjct  61   TEVLAGLRGWCTAPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARVRAAARRGT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            +AA+  +P +ET SFTVDLA K V + G +VHLTPTEWGMLEML RNRGKLVG+ ELL+E
Sbjct  121  SAADTSEPSVETASFTVDLAAKTVSRRGEQVHLTPTEWGMLEMLVRNRGKLVGQKELLRE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRF  224
            VWGPAY TETHYLRVYLAQLRRKLEDDP++PKHL+TE+GMGYRF
Sbjct  181  VWGPAYDTETHYLRVYLAQLRRKLEDDPANPKHLITEAGMGYRF  224


>gi|317506419|ref|ZP_07964224.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
 gi|316255299|gb|EFV14564.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
Length=226

 Score =  358 bits (919),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 175/225 (78%), Positives = 192/225 (86%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRALRINLT RG+ V TASTGAGALRAAAE  P+VV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQILRALRINLTARGFDVTTASTGAGALRAAAERQPEVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW   PVIVLSARTDSS+KV ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   FEVLAGLRGWTNVPVIVLSARTDSSEKVDALDAGADDYVTKPFGMDELLARLRAAVRRGA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                  +PV+ TDSF VDL  KKV KDGAEVHLTPTEWGMLE+L RN+GKLV + +LL E
Sbjct  121  RTQGEGEPVVVTDSFAVDLVAKKVTKDGAEVHLTPTEWGMLELLVRNQGKLVSQKDLLSE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGP+Y TETHYLRVYLAQLRRKLE DP+HP+HL+TE+GMGYRFE
Sbjct  181  VWGPSYKTETHYLRVYLAQLRRKLEADPAHPRHLITEAGMGYRFE  225


>gi|169630331|ref|YP_001703980.1| transcriptional regulatory protein KdpE [Mycobacterium abscessus 
ATCC 19977]
 gi|169242298|emb|CAM63326.1| Probable transcriptional regulatory protein KdpE [Mycobacterium 
abscessus]
Length=224

 Score =  357 bits (916),  Expect = 7e-97, Method: Compositional matrix adjust.
 Identities = 174/225 (78%), Positives = 198/225 (88%), Gaps = 2/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRA+RINL+ RGY+V+TAS+GAGALRAAAE  P+VVILDLGLPDM G
Sbjct  1    MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW   PVIVLSARTDS+DKV+ALDAGADDYVTKPFGMDEFLARLRAAVRR T
Sbjct  61   TEVLAGLRGWTDVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
              +   +PV+ T++F VDL+  KVI+DG EVHLTPTEW ML +L RNRGKLVG+ ELL E
Sbjct  121  PDS--AEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHE  178

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAY++ETHYLRVYLAQLRRKLE DP+HPKHLLTE+GMGYRF+
Sbjct  179  VWGPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQ  223


>gi|312140452|ref|YP_004007788.1| two component system response regulator kdpe [Rhodococcus equi 
103S]
 gi|325675932|ref|ZP_08155615.1| KDP operon response regulator KdpE [Rhodococcus equi ATCC 33707]
 gi|311889791|emb|CBH49108.1| two component system response regulator KdpE [Rhodococcus equi 
103S]
 gi|325553170|gb|EGD22849.1| KDP operon response regulator KdpE [Rhodococcus equi ATCC 33707]
Length=226

 Score =  348 bits (892),  Expect = 5e-94, Method: Compositional matrix adjust.
 Identities = 189/225 (84%), Positives = 206/225 (92%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRALRINL+VRGY+V TASTGA ALRAAAE  P+V++LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQILRALRINLSVRGYEVTTASTGAAALRAAAERHPEVIVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            I+VL GLRGW TAPVIVLSARTDSSDKV+ALDAGADDYVTKPFGMDEFLARLRAAVRR  
Sbjct  61   IEVLAGLRGWCTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            AAAE  +PV+ TDSFTVDLA KKV +DGAEVHLTPTEWGMLEML RN+GKLVG+ ELL+E
Sbjct  121  AAAETGEPVVVTDSFTVDLAAKKVTRDGAEVHLTPTEWGMLEMLVRNKGKLVGQKELLRE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYATETHYLRVYLAQLRRKLE DPS P+HLLTE+GMGYRF+
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEVDPSKPRHLLTETGMGYRFQ  225


>gi|183980660|ref|YP_001848951.1| transcriptional regulatory protein KdpE [Mycobacterium marinum 
M]
 gi|183173986|gb|ACC39096.1| transcriptional regulatory protein KdpE [Mycobacterium marinum 
M]
Length=226

 Score =  347 bits (891),  Expect = 6e-94, Method: Compositional matrix adjust.
 Identities = 192/226 (85%), Positives = 206/226 (92%), Gaps = 0/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLVIDDEPQILRALRIN +VRGY V+TA+TGA ALRAAAE  PDVVILDLGLPDMSG
Sbjct  1    MTRVLVIDDEPQILRALRINFSVRGYDVVTAATGAAALRAAAEQRPDVVILDLGLPDMSG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            I+VL GLRGW +APVIVLSAR+DSSDKVQALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   IEVLAGLRGWFSAPVIVLSARSDSSDKVQALDAGADDYVTKPFGMDELLARLRAAVRRAA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
             A + +QPVIET SFTVDLA KKVIK+G+EVHLTPTEWGMLEML RNRGKLVGR ELLKE
Sbjct  121  TATDTDQPVIETSSFTVDLATKKVIKNGSEVHLTPTEWGMLEMLVRNRGKLVGREELLKE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            VWGPAYA ETHYLRVYLAQLRRKLEDDP+HP+HLLTE+GMGYRF+ 
Sbjct  181  VWGPAYAKETHYLRVYLAQLRRKLEDDPAHPRHLLTEAGMGYRFDG  226


>gi|296393295|ref|YP_003658179.1| transcriptional regulator [Segniliparus rotundus DSM 44985]
 gi|296180442|gb|ADG97348.1| two component transcriptional regulator, winged helix family 
[Segniliparus rotundus DSM 44985]
Length=250

 Score =  345 bits (886),  Expect = 2e-93, Method: Compositional matrix adjust.
 Identities = 169/225 (76%), Positives = 189/225 (84%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT +LV+DDEPQILRALRINLT RG+ V TASTGAGALRAAA+  P+VV+LDLGLPDM G
Sbjct  1    MTKILVVDDEPQILRALRINLTARGFDVTTASTGAGALRAAAQCHPEVVLLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW   PVIVLSARTDSS+KV ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   FEVLAGLRGWTKIPVIVLSARTDSSEKVDALDAGADDYVTKPFGMDELLARLRAAVRRGA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                  +PV+  DSF VDL  KKV KD  EVHLTPTEWG+LE+L RN+GKLV + E+L E
Sbjct  121  NNQPGGEPVVAADSFVVDLVAKKVTKDDKEVHLTPTEWGVLELLVRNQGKLVSQKEILSE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGP+Y TETHYLRVYLAQLRRKLE DP++P+HLLTE+GMGYRFE
Sbjct  181  VWGPSYKTETHYLRVYLAQLRRKLEADPANPRHLLTEAGMGYRFE  225


>gi|111018238|ref|YP_701210.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|110817768|gb|ABG93052.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
Length=226

 Score =  340 bits (873),  Expect = 7e-92, Method: Compositional matrix adjust.
 Identities = 182/225 (81%), Positives = 204/225 (91%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRALRINL+VRGY V+TA++GA ALRAAAE PPDV++LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQILRALRINLSVRGYDVVTAASGAAALRAAAERPPDVIVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW  APVIVLSARTDS+DKV+ALDAGADDYVTKPFGMDEFLAR+RAA RR T
Sbjct  61   TEVLAGLRGWCPAPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARVRAAARRAT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
             A +  +PV+ETDSFTVDLA K V + GAEVHLTPTEWGMLEML RN+GKLVG+ ELL+E
Sbjct  121  TAVDTSEPVVETDSFTVDLAAKTVRRAGAEVHLTPTEWGMLEMLVRNKGKLVGQKELLRE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHP+HL+TE+GMGYRF+
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPRHLITEAGMGYRFQ  225


>gi|226360365|ref|YP_002778143.1| turgor pressure transcriptional regulator KdpE [Rhodococcus opacus 
B4]
 gi|226238850|dbj|BAH49198.1| turgor pressure transcriptional regulator KdpE [Rhodococcus opacus 
B4]
Length=226

 Score =  338 bits (868),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 181/225 (81%), Positives = 203/225 (91%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT +LV+DDEPQILRALRINL+VRGY V+TA++GA ALRAAAE PPDV++LDLGLPDM G
Sbjct  1    MTRILVVDDEPQILRALRINLSVRGYDVVTAASGAAALRAAAERPPDVIVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +VL GLRGW  APVIVLSARTDS+DKV ALDAGADDYVTKPFGMDEFLAR+RAA RR T
Sbjct  61   TEVLAGLRGWCPAPVIVLSARTDSADKVDALDAGADDYVTKPFGMDEFLARVRAAARRAT  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
             A +  +PV+ETDSFTVDLA K V + GAEVHLTPTEWGMLEML RN+GKLVG+ ELL+E
Sbjct  121  TAVDTSEPVVETDSFTVDLAAKTVRRAGAEVHLTPTEWGMLEMLVRNKGKLVGQKELLRE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYATETHYLRVYLAQLRRKLEDDPSHP+HL+TE+GMGYRF+
Sbjct  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPRHLITEAGMGYRFQ  225


>gi|302525129|ref|ZP_07277471.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
 gi|302434024|gb|EFL05840.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
Length=232

 Score =  333 bits (853),  Expect = 1e-89, Method: Compositional matrix adjust.
 Identities = 161/224 (72%), Positives = 190/224 (85%), Gaps = 1/224 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DDEPQI+RALRINL  RGY+VITA  G  AL+A AE  PDVV+LDLGLPD+ G +V
Sbjct  9    VLVVDDEPQIVRALRINLNARGYKVITAHDGTAALKAVAETKPDVVVLDLGLPDLDGTEV  68

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT-AA  122
            + GLRGW T P+IVLSAR DS+DKVQALDAGADDYVTKPFGMDE LARLRAAVRR++ A 
Sbjct  69   IAGLRGWTTVPIIVLSARGDSADKVQALDAGADDYVTKPFGMDELLARLRAAVRRSSVAG  128

Query  123  AELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVW  182
             +  + V++T SFT+DLA KKV+++G EVHLT TEWG+LE+L RNRG+LV + +LL EVW
Sbjct  129  TDGAEAVVDTGSFTIDLAAKKVLREGREVHLTKTEWGVLELLVRNRGRLVAQKQLLHEVW  188

Query  183  GPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            GP+Y TE+HYLRVYLAQLRRKLE +PS P+HLLTE GMGYRFEA
Sbjct  189  GPSYETESHYLRVYLAQLRRKLEPEPSRPRHLLTEPGMGYRFEA  232


>gi|291007109|ref|ZP_06565082.1| sensor histidine kinase [Saccharopolyspora erythraea NRRL 2338]
Length=1105

 Score =  331 bits (849),  Expect = 5e-89, Method: Compositional matrix adjust.
 Identities = 169/225 (76%), Positives = 194/225 (87%), Gaps = 0/225 (0%)

Query  1     MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
             MT VLV+DDEPQ+LRALRINLT RGY+V+TA  G  ALRAA +  PD V+LDLGLPDM G
Sbjct  880   MTRVLVVDDEPQLLRALRINLTARGYEVLTAVDGKAALRAAGDGKPDAVVLDLGLPDMDG  939

Query  61    IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
              +V+ GLRGW T P+IVLSARTDS+DKV ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  940   SEVIAGLRGWTTVPIIVLSARTDSTDKVHALDAGADDYVTKPFGMDELLARLRAAVRRAN  999

Query  121   AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
              A   +QPV+ET +F+VDLA KKV ++GAEVHLTPTEWGMLE+L RN+G+LVG+ +LLK+
Sbjct  1000  TADREDQPVVETATFSVDLAAKKVRREGAEVHLTPTEWGMLEVLVRNKGRLVGQKQLLKD  1059

Query  181   VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
             VWGPAYA ETHYLRVYLAQLRRKLE DPS P+HL+TE+GMGYRFE
Sbjct  1060  VWGPAYANETHYLRVYLAQLRRKLEADPSRPRHLITEAGMGYRFE  1104


>gi|134102522|ref|YP_001108183.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133915145|emb|CAM05258.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
Length=226

 Score =  330 bits (845),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 169/225 (76%), Positives = 194/225 (87%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQ+LRALRINLT RGY+V+TA  G  ALRAA +  PD V+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQLLRALRINLTARGYEVLTAVDGKAALRAAGDGKPDAVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +V+ GLRGW T P+IVLSARTDS+DKV ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   SEVIAGLRGWTTVPIIVLSARTDSTDKVHALDAGADDYVTKPFGMDELLARLRAAVRRAN  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
             A   +QPV+ET +F+VDLA KKV ++GAEVHLTPTEWGMLE+L RN+G+LVG+ +LLK+
Sbjct  121  TADREDQPVVETATFSVDLAAKKVRREGAEVHLTPTEWGMLEVLVRNKGRLVGQKQLLKD  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYA ETHYLRVYLAQLRRKLE DPS P+HL+TE+GMGYRFE
Sbjct  181  VWGPAYANETHYLRVYLAQLRRKLEADPSRPRHLITEAGMGYRFE  225


>gi|256379954|ref|YP_003103614.1| winged helix family two component transcriptional regulator [Actinosynnema 
mirum DSM 43827]
 gi|255924257|gb|ACU39768.1| two component transcriptional regulator, winged helix family 
[Actinosynnema mirum DSM 43827]
Length=226

 Score =  326 bits (836),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 166/225 (74%), Positives = 192/225 (86%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RALRINL+ RGYQV+TA  GA ALRAAAE  PDVV+LDLGLPD+ G
Sbjct  1    MTKVLVVDDEPQIVRALRINLSARGYQVLTAHDGAAALRAAAEGKPDVVVLDLGLPDVDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             +V+ GLRGW T P+IVLSAR DS+DKV+ALDAGADDYVTKPFGMDE LARLRAAVRR+ 
Sbjct  61   TEVIAGLRGWTTVPIIVLSARADSTDKVEALDAGADDYVTKPFGMDELLARLRAAVRRSA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            A A+  + V+ T +FTVDL  KKV ++ AEVHLTPTEWG+LE+L RN GKLV + +LL+E
Sbjct  121  APADAGEAVVRTGAFTVDLVAKKVHREDAEVHLTPTEWGLLEVLVRNPGKLVAQRQLLQE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAYA ETHYLRVYLAQLRRKLE +PS P+HL+TE GMGYRFE
Sbjct  181  VWGPAYAKETHYLRVYLAQLRRKLEPEPSRPRHLVTEPGMGYRFE  225


>gi|326384127|ref|ZP_08205810.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
 gi|326197287|gb|EGD54478.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
Length=230

 Score =  318 bits (814),  Expect = 5e-85, Method: Compositional matrix adjust.
 Identities = 154/222 (70%), Positives = 182/222 (82%), Gaps = 1/222 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DDEPQ+LRALRINL  RG++V TA+TGA AL AA++ PPDVV+LDLGLPDM G  V
Sbjct  7    VLVVDDEPQLLRALRINLRARGFEVTTAATGAQALEAASKRPPDVVVLDLGLPDMDGFTV  66

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAA  123
            L GLRGW + PVIVLSARTD++DKVQALDAGADDYVTKPFGM+EFLARLRAA+RR TA+ 
Sbjct  67   LAGLRGWTSVPVIVLSARTDAADKVQALDAGADDYVTKPFGMEEFLARLRAAIRRGTASG  126

Query  124  -ELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVW  182
               E PV+   +  VDLA K+V +DG  V LTPTEWG+LE+L R+   LVG+ E+L  VW
Sbjct  127  IPAEAPVVRAGALEVDLAAKRVTRDGEPVRLTPTEWGVLELLVRSEPNLVGQREILTAVW  186

Query  183  GPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRF  224
            GP Y  +T+YLRVYLA LRRKLE DPSHP+HL+TE+GMGYRF
Sbjct  187  GPTYVNQTNYLRVYLAALRRKLEADPSHPRHLITEAGMGYRF  228


>gi|289442448|ref|ZP_06432192.1| transcriptional regulator kdpE [Mycobacterium tuberculosis T46]
 gi|289415367|gb|EFD12607.1| transcriptional regulator kdpE [Mycobacterium tuberculosis T46]
Length=159

 Score =  317 bits (813),  Expect = 6e-85, Method: Compositional matrix adjust.
 Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%)

Query  71   LTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVI  130
            LTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVI
Sbjct  4    LTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVI  63

Query  131  ETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATET  190
            ETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATET
Sbjct  64   ETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWGPAYATET  123

Query  191  HYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            HYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
Sbjct  124  HYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  159


>gi|54023538|ref|YP_117780.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
 gi|54015046|dbj|BAD56416.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
Length=226

 Score =  317 bits (812),  Expect = 9e-85, Method: Compositional matrix adjust.
 Identities = 160/225 (72%), Positives = 190/225 (85%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT +LV+DDEPQILRALRINLT RGY+V+TA+ G  ALRAAA+  PDV++LDLGLPD+ G
Sbjct  1    MTRILVVDDEPQILRALRINLTARGYEVVTAADGRSALRAAAQQRPDVIVLDLGLPDLDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            I+VL GL GW +APVIVLSAR+D++DKV ALD GADDYVTKPFGM+EFLAR+RAAVRR  
Sbjct  61   IEVLAGLHGWCSAPVIVLSARSDAADKVAALDTGADDYVTKPFGMEEFLARIRAAVRRAA  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
            A  +L +P + TD+F VDLA KKV +DGA+VHLTPTEW MLEML R+RGKLVG+ ELL E
Sbjct  121  ATPDLPEPTVVTDAFVVDLAAKKVTRDGADVHLTPTEWSMLEMLVRHRGKLVGQRELLTE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            +WGP+Y  +THYLRVYL QLR KLE DPS P++L+TE G GYRFE
Sbjct  181  IWGPSYVGQTHYLRVYLTQLRHKLEPDPSRPRYLITEPGRGYRFE  225


>gi|300783817|ref|YP_003764108.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|299793331|gb|ADJ43706.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|340525210|gb|AEK40415.1| two-component system response regulator [Amycolatopsis mediterranei 
S699]
Length=232

 Score =  314 bits (805),  Expect = 6e-84, Method: Compositional matrix adjust.
 Identities = 161/224 (72%), Positives = 188/224 (84%), Gaps = 2/224 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DDEPQI+RALRINLT RGY+VITA  G  AL+A AE  PDVV+LDLGLPD+ G +V
Sbjct  8    VLVVDDEPQIVRALRINLTARGYKVITAHDGTAALKAVAETKPDVVVLDLGLPDLDGTEV  67

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRN-TAA  122
            + GLRGW T P+IVLSAR DS+DKV+ALDAGADDYVTKPFGMDE LARLRAAVRR+  A 
Sbjct  68   IAGLRGWTTVPIIVLSARGDSADKVEALDAGADDYVTKPFGMDELLARLRAAVRRSAVAG  127

Query  123  AELEQPVIETDSFTVDLAGKKVIK-DGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEV  181
            A+    V++T SF+VDLA KKV + DG EVHLT TEWG+LE+L RNRG+LV + +LL EV
Sbjct  128  ADDADAVVDTASFSVDLAAKKVRRHDGVEVHLTKTEWGVLELLVRNRGRLVAQKQLLHEV  187

Query  182  WGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            WGP+Y TE+HYLRVYLAQLRRKLE +PS P+HLLTE G+GYRFE
Sbjct  188  WGPSYETESHYLRVYLAQLRRKLEREPSRPRHLLTEPGIGYRFE  231


>gi|333921901|ref|YP_004495482.1| phosphate regulon transcriptional regulator PhoB [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333484122|gb|AEF42682.1| Phosphate regulon transcriptional regulatory protein PhoB [Amycolicicoccus 
subflavus DQS3-9A1]
Length=226

 Score =  314 bits (804),  Expect = 7e-84, Method: Compositional matrix adjust.
 Identities = 150/224 (67%), Positives = 178/224 (80%), Gaps = 0/224 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDE QILRALRI L   GY V TA+ G+ ALRA A   PD+V+LDLGLPD+ G
Sbjct  1    MTTVLVVDDENQILRALRITLAAHGYTVKTAADGSAALRAVATEKPDIVVLDLGLPDIEG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
             DV+ G+RGW T P++VLSARTDS DKV ALDAGADDYVTKPFGMDEFLARLR+A+RR  
Sbjct  61   TDVIHGIRGWSTVPIVVLSARTDSGDKVAALDAGADDYVTKPFGMDEFLARLRSALRRAQ  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                    V+E D  T+DLA + V +DG++VHLTPTEW +LE+L RNRG+LV + ++L+ 
Sbjct  121  TVESTPDTVVEADGLTIDLAARCVRRDGSDVHLTPTEWSILELLVRNRGRLVTQKQVLQA  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRF  224
            VWGP+Y TETHYLRVYLAQLRRKLE DPS P++LLTE GMGYRF
Sbjct  181  VWGPSYGTETHYLRVYLAQLRRKLEGDPSRPRYLLTEPGMGYRF  224


>gi|116671596|ref|YP_832529.1| two component transcriptional regulator [Arthrobacter sp. FB24]
 gi|116611705|gb|ABK04429.1| two component transcriptional regulator, winged helix family 
[Arthrobacter sp. FB24]
Length=224

 Score =  308 bits (790),  Expect = 3e-82, Method: Compositional matrix adjust.
 Identities = 148/225 (66%), Positives = 181/225 (81%), Gaps = 2/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MTLVL+I+DE Q+ RA++INL   GYQ ITA  GA  L+ AA+HP D+V+LDLGLPDM G
Sbjct  1    MTLVLIIEDEAQLARAMQINLRAHGYQAITAGLGADGLKLAAQHPVDIVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            ++V+ G+RGW + PVIVLSAR  S DKV+ALDAGADDYVTKPFG+DE LARLRAA RR+ 
Sbjct  61   VEVIRGIRGWSSVPVIVLSARHASEDKVEALDAGADDYVTKPFGLDELLARLRAASRRSP  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
              A+ E P +ET  F VDLA +KV++DG E+ LTPTEW +LE+L RN+GKLV + +LL +
Sbjct  121  --AQREAPTVETADFVVDLAARKVVRDGHEIRLTPTEWNILELLVRNQGKLVSQQQLLTQ  178

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWG AYA ET YLRVYLAQLRRKLE DP+ P+HL TE+GMGYRF+
Sbjct  179  VWGQAYAKETQYLRVYLAQLRRKLEQDPARPRHLHTEAGMGYRFD  223


>gi|262203938|ref|YP_003275146.1| response regulator receiver [Gordonia bronchialis DSM 43247]
 gi|262087285|gb|ACY23253.1| response regulator receiver [Gordonia bronchialis DSM 43247]
Length=231

 Score =  307 bits (786),  Expect = 8e-82, Method: Compositional matrix adjust.
 Identities = 150/224 (67%), Positives = 179/224 (80%), Gaps = 1/224 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DDEPQ+LRALRINL  RG+ V TA+ G  AL AA+   P VV+LDLGLPDM G+ V
Sbjct  7    VLVVDDEPQLLRALRINLNARGFAVTTAADGREALTAASRMDPHVVVLDLGLPDMDGLTV  66

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAA  123
            L GLRGW T PVIVLSAR+D++DKV ALDAGADDYVTKPFGM+EFLARLRAAVRR   ++
Sbjct  67   LEGLRGWTTVPVIVLSARSDAADKVSALDAGADDYVTKPFGMEEFLARLRAAVRRGAVSS  126

Query  124  EL-EQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVW  182
             L E P+++  SF VDLA K+V + G  +HLTPTEW +LE+L RN GKLV + E+L  VW
Sbjct  127  GLPEVPMVDAGSFQVDLAAKQVTRHGERIHLTPTEWEILEILVRNEGKLVSQKEILNSVW  186

Query  183  GPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA  226
            GP Y  +++YLRVYLA LRRKLEDDP HP+HL+TE+GMGYRF A
Sbjct  187  GPTYLGQSNYLRVYLASLRRKLEDDPVHPRHLITEAGMGYRFVA  230


>gi|291454638|ref|ZP_06594028.1| response regulator [Streptomyces albus J1074]
 gi|291357587|gb|EFE84489.1| response regulator [Streptomyces albus J1074]
Length=231

 Score =  305 bits (781),  Expect = 3e-81, Method: Compositional matrix adjust.
 Identities = 150/226 (67%), Positives = 179/226 (80%), Gaps = 1/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL +NL  R Y+V +A  G  ALR AAE  PDV++LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALELNLRARQYEVDSAGDGTTALRLAAERHPDVIVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            +DVL GLR W   PV+VLSAR  S +KVQALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VDVLRGLRSWSRVPVLVLSARQSSDEKVQALDAGADDYVTKPFGMDELLARLRAAVRRTE  120

Query  121  -AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
             AA + E  V++   FTVDLA K+V + G +V LTPTEW +LE+L RN G+LV + +LL+
Sbjct  121  PAAPDEEAEVVDAADFTVDLAAKRVHRQGRDVRLTPTEWHLLEVLVRNTGRLVSQKQLLQ  180

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWGP+Y TE++YLRVY+AQLRRKLE DP+HP+H +TE GMGYRFE
Sbjct  181  EVWGPSYGTESNYLRVYMAQLRRKLETDPAHPRHFITEPGMGYRFE  226


>gi|119960910|ref|YP_948727.1| KDP operon transcriptional regulatory [Arthrobacter aurescens 
TC1]
 gi|119947769|gb|ABM06680.1| KDP operon transcriptional regulatory [Arthrobacter aurescens 
TC1]
Length=224

 Score =  297 bits (761),  Expect = 7e-79, Method: Compositional matrix adjust.
 Identities = 139/225 (62%), Positives = 178/225 (80%), Gaps = 2/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MTLVL+++DE +I RA+++ L   GYQ +T  TGA AL+A A+ P ++V+LDLGLPDM G
Sbjct  1    MTLVLIVEDEARIARAMQVTLQANGYQALTVGTGADALQATAKQPVEIVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            ++++  +RGW + P+IVLSAR  S DKV+ALDAGADDYVTKPFG+DE LARLR A RR  
Sbjct  61   VEIIRRIRGWSSMPIIVLSARHASEDKVEALDAGADDYVTKPFGLDELLARLRVASRR--  118

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
               E E+P + T  F VDLAGKK++KDG+EV LTPTEW +LE+L RN+GKLV + ++L +
Sbjct  119  VVTEHEEPTLATTDFMVDLAGKKIVKDGSEVRLTPTEWNILELLVRNKGKLVSQQQILTQ  178

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWG AYA ET YLRVY+AQLRRKLE DP+ P+HL TE+GMGYRF+
Sbjct  179  VWGQAYAKETQYLRVYIAQLRRKLERDPAEPRHLHTEAGMGYRFD  223


>gi|182435453|ref|YP_001823172.1| putative two-component system response regulator [Streptomyces 
griseus subsp. griseus NBRC 13350]
 gi|326776090|ref|ZP_08235355.1| two component transcriptional regulator, winged helix family 
[Streptomyces cf. griseus XylebKG-1]
 gi|178463969|dbj|BAG18489.1| putative two-component system response regulator [Streptomyces 
griseus subsp. griseus NBRC 13350]
 gi|326656423|gb|EGE41269.1| two component transcriptional regulator, winged helix family 
[Streptomyces griseus XylebKG-1]
Length=231

 Score =  293 bits (751),  Expect = 9e-78, Method: Compositional matrix adjust.
 Identities = 150/230 (66%), Positives = 179/230 (78%), Gaps = 6/230 (2%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALVINLKARQYEVDAAPDGATALQLAAARHPDVVLLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRR--  118
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRA+VRR  
Sbjct  61   VEVIRGLRGWTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRASVRRAE  120

Query  119  ---NTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRG  175
                   AE +  ++ET  FTVDLA KKV + G +V LTPTEW +LE+L RN G+LV + 
Sbjct  121  PVGQEGGAE-DIALVETAGFTVDLAAKKVHRAGRDVRLTPTEWHLLEVLVRNGGRLVSQK  179

Query  176  ELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            +LL+EVWGP+Y TET+YLRVY+AQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  180  QLLQEVWGPSYGTETNYLRVYMAQLRRKLEADPSHPRHFVTEPGMGYRFE  229


>gi|311896069|dbj|BAJ28477.1| putative two-component system response regulator [Kitasatospora 
setae KM-6054]
Length=226

 Score =  291 bits (745),  Expect = 4e-77, Method: Compositional matrix adjust.
 Identities = 153/225 (68%), Positives = 178/225 (80%), Gaps = 0/225 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V +A  GA AL  AA   PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALVINLKARKYEVDSAHDGASALELAAARHPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            ++V+ GLRGW   P+IVLSAR  S +KV+ALDAGADDYVTKPFGMDE LAR+RAAVRR  
Sbjct  61   VEVIRGLRGWTRVPIIVLSARHASDEKVEALDAGADDYVTKPFGMDELLARMRAAVRRAE  120

Query  121  AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                  + V+ TDSFTVDLA KKV + GA+V LTPTEW +LE+L RN G+LV + +LL+E
Sbjct  121  PVTAEGESVVATDSFTVDLAAKKVNRQGADVRLTPTEWHLLEVLVRNSGRLVSQTQLLQE  180

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGPAY  ET+YLRVYLAQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  181  VWGPAYRKETNYLRVYLAQLRRKLEADPSHPRHFITEPGMGYRFE  225


>gi|284034649|ref|YP_003384580.1| winged helix family two component transcriptional regulator [Kribbella 
flavida DSM 17836]
 gi|283813942|gb|ADB35781.1| two component transcriptional regulator, winged helix family 
[Kribbella flavida DSM 17836]
Length=225

 Score =  288 bits (737),  Expect = 4e-76, Method: Compositional matrix adjust.
 Identities = 144/226 (64%), Positives = 177/226 (79%), Gaps = 3/226 (1%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL+INL  R Y+V  A TG  AL+ AA+HPPD+VILDLGLPD+ G
Sbjct  1    MTRVLVVDDEPQIVRALQINLKARRYEVHVAGTGTAALQVAAQHPPDLVILDLGLPDLDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            I+V+ GLRGW  AP++VLS RTDS+DKV+ALDAGADDYVTKPFG+DE LAR+RAA+RR++
Sbjct  61   IEVIRGLRGWTEAPILVLSGRTDSTDKVEALDAGADDYVTKPFGIDELLARMRAALRRSS  120

Query  121  AAAELEQPVIETDSFTVDLAGKKV-IKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
                 EQPV+      VDLA K+V + +G +V LTPTEW +LE+L R+ GKL+ + +LL 
Sbjct  121  GGT--EQPVVTVGEAKVDLAAKRVTLGNGEDVRLTPTEWHLLEVLVRHPGKLMSQRQLLL  178

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWGP Y T    LR Y+AQLRRKLE DP+ P+HL TE GMGYRFE
Sbjct  179  EVWGPGYETAGGNLRFYMAQLRRKLEPDPARPQHLRTEPGMGYRFE  224


>gi|302554679|ref|ZP_07307021.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
 gi|302472297|gb|EFL35390.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
Length=227

 Score =  287 bits (735),  Expect = 7e-76, Method: Compositional matrix adjust.
 Identities = 155/226 (69%), Positives = 180/226 (80%), Gaps = 1/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALVINLKARKYEVDAAHDGATALKLAAARQPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            +DV+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VDVIRGLRGWTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  120

Query  121  AAAELEQP-VIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
             A   E   V+ETD FTVDLA KKV++ G +V LTPTEW +LE+L R  G+LVG+ +LL+
Sbjct  121  PAGGGEDDVVVETDEFTVDLAAKKVVRAGKDVRLTPTEWHLLEVLVRGGGRLVGQKQLLQ  180

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWGP+Y TET+YLRVY+AQLRRKLE DPSHPKH +TE GMGYRFE
Sbjct  181  EVWGPSYGTETNYLRVYMAQLRRKLEADPSHPKHFITEPGMGYRFE  226


>gi|297559280|ref|YP_003678254.1| two component transcriptional regulator [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
 gi|296843728|gb|ADH65748.1| two component transcriptional regulator, winged helix family 
[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111]
Length=231

 Score =  287 bits (734),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 140/222 (64%), Positives = 179/222 (81%), Gaps = 2/222 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DD+ QI+RA+RINL  RG+ V TA+ GA ALR AA++ PDVV+LDLGLPDM G++V
Sbjct  3    VLVVDDDMQIIRAMRINLRARGHDVDTAADGASALRLAADNHPDVVLLDLGLPDMEGMEV  62

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAA  123
            +  LRGW   P+IVLSAR  + +KV+ LD+GADDYVTKPFGMDE LAR+RAA RR+    
Sbjct  63   IQRLRGWSQVPIIVLSARHSAGEKVRCLDSGADDYVTKPFGMDELLARMRAAERRSVRVD  122

Query  124  ELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVWG  183
              E PV+ T SFTVDL  K+V+++G EV LTPTEW +LE+LAR+ G+LV + +LL +VWG
Sbjct  123  --EAPVVRTPSFTVDLGAKRVLREGEEVRLTPTEWHILEILARHAGQLVSQRQLLHDVWG  180

Query  184  PAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            PAY +ET+YLRVY+AQLRRKLE DP+ P++L+TE+G GYRFE
Sbjct  181  PAYQSETNYLRVYMAQLRRKLEPDPACPRYLITEAGRGYRFE  222


>gi|328885593|emb|CCA58832.1| DNA-binding response regulator KdpE [Streptomyces venezuelae 
ATCC 10712]
Length=228

 Score =  287 bits (734),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 155/227 (69%), Positives = 181/227 (80%), Gaps = 2/227 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V  A  GA ALR AAE  PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALVINLKARKYEVDAAPDGATALRLAAERHPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRN-  119
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VEVIKGLRGWTRVPILVLSARQTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  120

Query  120  -TAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELL  178
                AE    V+ET+ FTVDLA KKV +DG +V LTPTEW +LE+L RN G+LV + +LL
Sbjct  121  PVGGAEDGVVVVETEGFTVDLAAKKVHRDGRDVRLTPTEWHLLEVLVRNGGRLVSQKQLL  180

Query  179  KEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            +EVWGP+Y TET+YLRVY+AQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  181  QEVWGPSYGTETNYLRVYMAQLRRKLESDPSHPRHFVTEPGMGYRFE  227


>gi|297153701|gb|ADI03413.1| putative two-component system response regulator [Streptomyces 
bingchenggensis BCW-1]
Length=227

 Score =  286 bits (732),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 142/226 (63%), Positives = 172/226 (77%), Gaps = 1/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV++D+PQ++RAL INL  R Y V  A  G  ALR AA H PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVEDDPQLVRALVINLQARHYDVDAAPDGTTALRLAASHQPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            +DV+  LRGW   PV+VLSAR  S +KV ALDAGADDY+TKPF MDE LARLRA+VRR  
Sbjct  61   VDVIKALRGWTPVPVLVLSARRASEEKVAALDAGADDYMTKPFSMDELLARLRASVRRTE  120

Query  121  AAAEL-EQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
            A     E  +++TD FTVDL  KK  +DG +VHLTPTEW +LE+L  N G+LV +  LL+
Sbjct  121  AGPTAPETTLVKTDDFTVDLTAKKAHRDGRDVHLTPTEWHLLEILVTNPGRLVTQRHLLQ  180

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWG + + +T+YLRVY+AQLRRKLE DPSHP++L+TE GMGYRFE
Sbjct  181  EVWGASQSNKTNYLRVYMAQLRRKLEADPSHPRYLITEPGMGYRFE  226


>gi|29828937|ref|NP_823571.1| two-component system response regulator for high-affinity potassium 
transport system [Streptomyces avermitilis MA-4680]
 gi|29606042|dbj|BAC70106.1| putative two-component system response regulator for high-affinity 
potassium transport system [Streptomyces avermitilis MA-4680]
Length=238

 Score =  285 bits (730),  Expect = 3e-75, Method: Compositional matrix adjust.
 Identities = 154/225 (69%), Positives = 179/225 (80%), Gaps = 1/225 (0%)

Query  2    TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGI  61
            T VLV+DDEPQI+RAL INL  R Y+V +A  GA AL  AA   PDVV+LDLGLPDM G+
Sbjct  13   TRVLVVDDEPQIVRALVINLKARKYEVDSAHDGATALHVAAARHPDVVVLDLGLPDMDGV  72

Query  62   DVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTA  121
            +V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR   
Sbjct  73   EVIRGLRGWTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAEP  132

Query  122  AAELEQPVI-ETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                E  VI ET+ FTVDLA KKV +DG +V LTPTEW +LE+L RN G+LVG+ +LL+E
Sbjct  133  TGGGEDDVIVETEDFTVDLAAKKVNRDGRDVRLTPTEWHLLEVLVRNTGRLVGQKQLLQE  192

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGP+Y TET+YLRVY+AQLRRKLE DPSHPKH +TE GMGYRFE
Sbjct  193  VWGPSYGTETNYLRVYMAQLRRKLESDPSHPKHFITEPGMGYRFE  237


>gi|325001104|ref|ZP_08122216.1| two component transcriptional regulator, winged helix family 
protein [Pseudonocardia sp. P1]
Length=231

 Score =  284 bits (727),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 156/225 (70%), Positives = 178/225 (80%), Gaps = 1/225 (0%)

Query  2    TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGI  61
            T VLV+DD+PQILRALRINL   GY V+ A  GA ALR AA+  PDVV+LDLGLPD+ G 
Sbjct  6    TTVLVVDDDPQILRALRINLAAHGYAVLLAEDGAAALRRAADGHPDVVVLDLGLPDLHGS  65

Query  62   DVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTA  121
            +V+ G+RGW   P+IVLSAR DS DKV+ALDAGADDYVTKPFGM E LARLRAAVRR   
Sbjct  66   EVIEGIRGWSAVPIIVLSARGDSGDKVRALDAGADDYVTKPFGMAELLARLRAAVRRAAV  125

Query  122  AAELEQPVIETDSFTVDLAGKKVIKD-GAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE  180
                 + VI TD+FTVDLA K V+   G +VHLTPTEWG+LE+L RNRGKLV R  LL E
Sbjct  126  TTVDGEAVIRTDAFTVDLAAKTVVDSGGGDVHLTPTEWGILEVLVRNRGKLVDRRRLLHE  185

Query  181  VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            VWGP+Y TETHYLRVYLAQLRRKLE  PS P++L+TE+GMGYRFE
Sbjct  186  VWGPSYDTETHYLRVYLAQLRRKLEPVPSAPRYLITEAGMGYRFE  230


>gi|163839669|ref|YP_001624074.1| two-component response regulator [Renibacterium salmoninarum 
ATCC 33209]
 gi|162953145|gb|ABY22660.1| two-component response regulator [Renibacterium salmoninarum 
ATCC 33209]
Length=227

 Score =  284 bits (726),  Expect = 8e-75, Method: Compositional matrix adjust.
 Identities = 139/228 (61%), Positives = 171/228 (75%), Gaps = 5/228 (2%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQILRAL+INL   GY V T++ G  AL +AA HPPDVV+LD GLPD+ G
Sbjct  1    MTTVLVVDDEPQILRALQINLHAHGYTVHTSANGTDALASAAAHPPDVVVLDFGLPDIDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEF---LARLRAAVR  117
            ++V+ GLRGW   P+IVLSAR  S +KV ALDAGADDYVTKPFG+DEF   L   +    
Sbjct  61   LEVIAGLRGWTAVPIIVLSARHASEEKVAALDAGADDYVTKPFGLDEFLARLRAAQRRAE  120

Query  118  RNTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGEL  177
            ++T A     P + T+ F VDL  KKV++ G  V LTPTEW +LE+LARN G+LV + +L
Sbjct  121  QDTDAG--ASPTVATEDFVVDLQAKKVLRAGQRVRLTPTEWSILELLARNSGRLVSQQQL  178

Query  178  LKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            L +VWGPAYA ET YLRVY+ QLRRKLE DP++P+HL+ E+GMGYRFE
Sbjct  179  LTQVWGPAYAKETQYLRVYMGQLRRKLEPDPANPRHLIAEAGMGYRFE  226


>gi|326443958|ref|ZP_08218692.1| putative two-component system response regulator [Streptomyces 
clavuligerus ATCC 27064]
Length=229

 Score =  283 bits (724),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 151/227 (67%), Positives = 181/227 (80%), Gaps = 2/227 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G
Sbjct  1    MTRVLVVDDEPQIVRALVINLKARKYEVDAAPDGATALQLAAARHPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRN-  119
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VEVIKGLRGWTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  120

Query  120  -TAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELL  178
                 + +  ++ET+SFTVDLA KKV +DG +V LTPTEW +LE+L RN G+LV + +LL
Sbjct  121  PVGGGDDDVVIVETESFTVDLAAKKVNRDGRDVRLTPTEWHLLEVLVRNTGRLVSQKQLL  180

Query  179  KEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            +EVWGP+Y TET+YLRVY+AQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  181  QEVWGPSYGTETNYLRVYMAQLRRKLEADPSHPRHFITEPGMGYRFE  227


>gi|302541993|ref|ZP_07294335.1| DNA-binding response regulator KdpE [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302459611|gb|EFL22704.1| DNA-binding response regulator KdpE [Streptomyces himastatinicus 
ATCC 53653]
Length=227

 Score =  283 bits (724),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 149/226 (66%), Positives = 179/226 (80%), Gaps = 1/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            M  VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G
Sbjct  1    MNRVLVVDDEPQIVRALVINLKARKYEVDAAGDGATALKLAATRHPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VEVIKGLRGWTRVPILVLSARQTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  120

Query  121  AAAELEQP-VIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
             +   +   V+ETD F+VDLA KK  +DG +V LTPTEW +LE+L RN G+LV + +LL+
Sbjct  121  PSGPSDAAVVVETDGFSVDLAAKKAHRDGRDVRLTPTEWHLLEVLVRNEGRLVSQKQLLQ  180

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWGP+Y TET+YLRVY+AQLRRKLE+DPSHP+H +TE GMGYRFE
Sbjct  181  EVWGPSYGTETNYLRVYMAQLRRKLENDPSHPRHFITEPGMGYRFE  226


>gi|294815609|ref|ZP_06774252.1| putative two-component system response regulator [Streptomyces 
clavuligerus ATCC 27064]
 gi|294328208|gb|EFG09851.1| putative two-component system response regulator [Streptomyces 
clavuligerus ATCC 27064]
Length=247

 Score =  283 bits (724),  Expect = 2e-74, Method: Compositional matrix adjust.
 Identities = 142/227 (63%), Positives = 172/227 (76%), Gaps = 2/227 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            MT VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G
Sbjct  19   MTRVLVVDDEPQIVRALVINLKARKYEVDAAPDGATALQLAAARHPDVVVLDLGLPDMDG  78

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDE--FLARLRAAVRR  118
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE     R       
Sbjct  79   VEVIKGLRGWTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  138

Query  119  NTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELL  178
                 + +  ++ET+SFTVDLA KKV +DG +V LTPTEW +LE+L RN G+LV + +LL
Sbjct  139  PVGGGDDDVVIVETESFTVDLAAKKVNRDGRDVRLTPTEWHLLEVLVRNTGRLVSQKQLL  198

Query  179  KEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            +EVWGP+Y TET+YLRVY+AQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  199  QEVWGPSYGTETNYLRVYMAQLRRKLEADPSHPRHFITEPGMGYRFE  245


>gi|337768622|emb|CCB77335.1| KDP operon transcriptional regulatory protein kdpE [Streptomyces 
cattleya NRRL 8057]
Length=254

 Score =  282 bits (722),  Expect = 2e-74, Method: Compositional matrix adjust.
 Identities = 152/223 (69%), Positives = 178/223 (80%), Gaps = 1/223 (0%)

Query  4    VLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDV  63
            VLV+DDEPQI+RAL INL  R Y+V  A  GA AL+ AA   PDVV+LDLGLPDM G +V
Sbjct  31   VLVVDDEPQIVRALVINLRARKYEVDAAPDGATALQLAAARHPDVVVLDLGLPDMDGTEV  90

Query  64   LGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAA  123
            + GLRGW   P+IVLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR     
Sbjct  91   IKGLRGWTRVPIIVLSARQASDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAAPGG  150

Query  124  ELEQPV-IETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKEVW  182
            + E+ V +ETDSFTVDLA KKV +DG +V LTPTEW +LE+L R  G+LV + +LL+EVW
Sbjct  151  DGEEAVTVETDSFTVDLAAKKVNRDGTDVRLTPTEWHLLEVLVRTPGRLVSQKQLLQEVW  210

Query  183  GPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            GPAY TET+YLRVY+AQLRRKLE DP+HP+H +TE GMGYRFE
Sbjct  211  GPAYGTETNYLRVYMAQLRRKLEADPAHPRHFITEPGMGYRFE  253


>gi|297156667|gb|ADI06379.1| putative two-component system response regulator for high-affinity 
potassium transport system [Streptomyces bingchenggensis 
BCW-1]
Length=227

 Score =  282 bits (721),  Expect = 3e-74, Method: Compositional matrix adjust.
 Identities = 151/226 (67%), Positives = 178/226 (79%), Gaps = 1/226 (0%)

Query  1    MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG  60
            M  VLV+DDEPQI+RAL INL  R Y+V  AS GA ALR AA   PDVV+LDLGLPDM G
Sbjct  1    MNRVLVVDDEPQIVRALVINLKARKYEVDAASDGATALRLAATRHPDVVVLDLGLPDMDG  60

Query  61   IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT  120
            ++V+ GLRGW   P++VLSAR  S +KV+ALDAGADDYVTKPFGMDE LARLRAAVRR  
Sbjct  61   VEVIKGLRGWTRVPILVLSARQTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRAE  120

Query  121  AAAELE-QPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLK  179
                 +   V+ET+ FTVDLA KKV + G +V LTPTEW +LE+L RN G+LV + +LL+
Sbjct  121  PVGAADGGAVVETEGFTVDLAAKKVNRGGVDVRLTPTEWHLLEVLVRNTGRLVSQKQLLQ  180

Query  180  EVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFE  225
            EVWGP+Y TET+YLRVY+AQLRRKLE DPSHP+H +TE GMGYRFE
Sbjct  181  EVWGPSYGTETNYLRVYMAQLRRKLEADPSHPRHFVTEPGMGYRFE  226



Lambda     K      H
   0.319    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 287912302678


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40