BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1032c Length=509 Score E Sequences producing significant alignments: (Bits) Value gi|15608172|ref|NP_215548.1| two component sensor histidine kina... 1021 0.0 gi|289573672|ref|ZP_06453899.1| two component system sensor hist... 1019 0.0 gi|289442455|ref|ZP_06432199.1| two component system sensor hist... 1019 0.0 gi|148822241|ref|YP_001286995.1| two component system sensor his... 1018 0.0 gi|340626044|ref|YP_004744496.1| two component sensor histidine ... 1013 0.0 gi|167968533|ref|ZP_02550810.1| two component sensor histidine k... 968 0.0 gi|254550018|ref|ZP_05140465.1| two component sensor histidine k... 967 0.0 gi|183984427|ref|YP_001852718.1| two-component sensor histidine ... 753 0.0 gi|118619707|ref|YP_908039.1| two component sensor histidine kin... 739 0.0 gi|240169875|ref|ZP_04748534.1| two-component sensor histidine k... 721 0.0 gi|41407099|ref|NP_959935.1| hypothetical protein MAP1001c [Myco... 679 0.0 gi|118463007|ref|YP_880423.1| two component sensor histidine kin... 678 0.0 gi|254774012|ref|ZP_05215528.1| two component sensor histidine k... 677 0.0 gi|296169905|ref|ZP_06851517.1| sensor histidine kinase TcrS [My... 677 0.0 gi|254820269|ref|ZP_05225270.1| two component sensor histidine k... 667 0.0 gi|342861636|ref|ZP_08718282.1| two component sensor histidine k... 657 0.0 gi|289753094|ref|ZP_06512472.1| LOW QUALITY PROTEIN: two compone... 612 4e-173 gi|253799936|ref|YP_003032937.1| two component system sensor his... 579 3e-163 gi|333992568|ref|YP_004525182.1| two-component sensor histidine ... 487 2e-135 gi|253799937|ref|YP_003032938.1| two component system sensor his... 442 7e-122 gi|118469988|ref|YP_887234.1| sensor histidine kinase [Mycobacte... 431 1e-118 gi|120403286|ref|YP_953115.1| integral membrane sensor signal tr... 423 3e-116 gi|324999381|ref|ZP_08120493.1| integral membrane sensor signal ... 320 4e-85 gi|86739036|ref|YP_479436.1| periplasmic sensor signal transduct... 303 5e-80 gi|145594663|ref|YP_001158960.1| ATPase domain-containing protei... 302 1e-79 gi|336460749|gb|EGO39637.1| signal transduction histidine kinase... 301 1e-79 gi|41406358|ref|NP_959194.1| hypothetical protein MAP0260 [Mycob... 301 2e-79 gi|118466581|ref|YP_879594.1| sensor histidine kinase [Mycobacte... 300 6e-79 gi|254773314|ref|ZP_05214830.1| sensor histidine kinase [Mycobac... 299 7e-79 gi|148273949|ref|YP_001223510.1| putative two-component system, ... 299 7e-79 gi|183985284|ref|YP_001853575.1| two-component sensor kinase Tcr... 296 4e-78 gi|111220169|ref|YP_710963.1| putative sensor histidine kinase [... 296 5e-78 gi|297158649|gb|ADI08361.1| putative two component system sensor... 295 1e-77 gi|50954149|ref|YP_061437.1| two-component system, sensor protei... 294 3e-77 gi|340628735|ref|YP_004747187.1| putative two component sensor k... 294 3e-77 gi|159037875|ref|YP_001537128.1| histidine kinase [Salinispora a... 293 4e-77 gi|342860016|ref|ZP_08716668.1| sensor histidine kinase [Mycobac... 293 6e-77 gi|312200459|ref|YP_004020520.1| integral membrane sensor signal... 291 3e-76 gi|31794934|ref|NP_857427.1| putative two component sensor kinas... 290 4e-76 gi|254366309|ref|ZP_04982353.1| hypothetical two component senso... 290 4e-76 gi|289556029|ref|ZP_06445239.1| two component system sensor kina... 290 4e-76 gi|254552878|ref|ZP_05143325.1| two component system sensor kina... 290 4e-76 gi|15843384|ref|NP_338421.1| sensor histidine kinase [Mycobacter... 290 5e-76 gi|170780990|ref|YP_001709322.1| putative two component sensor k... 290 5e-76 gi|289445363|ref|ZP_06435107.1| two component system sensor kina... 289 9e-76 gi|88856022|ref|ZP_01130684.1| two-component system, sensor prot... 289 9e-76 gi|333992681|ref|YP_004525295.1| two-component sensor kinase Tcr... 288 1e-75 gi|296166888|ref|ZP_06849305.1| sensor histidine kinase [Mycobac... 288 1e-75 gi|258654799|ref|YP_003203955.1| histidine kinase [Nakamurella m... 288 1e-75 gi|328883820|emb|CCA57059.1| Two-component system, sensor protei... 287 3e-75 >gi|15608172|ref|NP_215548.1| two component sensor histidine kinase TRCS [Mycobacterium tuberculosis H37Rv] gi|15840462|ref|NP_335499.1| sensor histidine kinase TcrS [Mycobacterium tuberculosis CDC1551] gi|31792224|ref|NP_854717.1| two component sensor histidine kinase TRCS [Mycobacterium bovis AF2122/97] 58 more sequence titles Length=509 Score = 1021 bits (2639), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/509 (100%), Positives = 509/509 (100%), Gaps = 0/509 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN Sbjct 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH Sbjct 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR Sbjct 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 Query 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 GSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 >gi|289573672|ref|ZP_06453899.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis K85] gi|339631094|ref|YP_004722736.1| two component sensor histidine kinase [Mycobacterium africanum GM041182] gi|289538103|gb|EFD42681.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis K85] gi|339330450|emb|CCC26115.1| two component sensor histidine kinase TRCS [Mycobacterium africanum GM041182] Length=509 Score = 1019 bits (2635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/509 (99%), Positives = 508/509 (99%), Gaps = 0/509 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN Sbjct 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGI CH Sbjct 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGIACH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR Sbjct 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 Query 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 GSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 >gi|289442455|ref|ZP_06432199.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T46] gi|289569013|ref|ZP_06449240.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T17] gi|289749565|ref|ZP_06508943.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T92] gi|289415374|gb|EFD12614.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T46] gi|289542767|gb|EFD46415.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T17] gi|289690152|gb|EFD57581.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis T92] Length=509 Score = 1019 bits (2634), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/509 (99%), Positives = 508/509 (99%), Gaps = 0/509 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 E LHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ECLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN Sbjct 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH Sbjct 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR Sbjct 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 Query 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 GSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 >gi|148822241|ref|YP_001286995.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis F11] gi|148720768|gb|ABR05393.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis F11] Length=509 Score = 1018 bits (2631), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/509 (99%), Positives = 508/509 (99%), Gaps = 0/509 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ES HALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ESRHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN Sbjct 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH Sbjct 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR Sbjct 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 Query 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 GSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 >gi|340626044|ref|YP_004744496.1| two component sensor histidine kinase TRCS [Mycobacterium canettii CIPT 140010059] gi|340004234|emb|CCC43374.1| two component sensor histidine kinase TRCS [Mycobacterium canettii CIPT 140010059] Length=509 Score = 1013 bits (2619), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/509 (99%), Positives = 507/509 (99%), Gaps = 0/509 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKA CWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKALCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESLHALNHSYTRYRDSA+TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ESLHALNHSYTRYRDSARTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN Sbjct 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH Sbjct 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASK RSNGSGHGLGLAIVSSIVKAHR Sbjct 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKYRSNGSGHGLGLAIVSSIVKAHR 480 Query 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 GSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 481 GSVTAESGNGQTVFRVRLPMIEQQIATTA 509 >gi|167968533|ref|ZP_02550810.1| two component sensor histidine kinase TrcS [Mycobacterium tuberculosis H37Ra] gi|294995221|ref|ZP_06800912.1| two component sensor histidine kinase TRCS [Mycobacterium tuberculosis 210] gi|297730546|ref|ZP_06959664.1| two component sensor histidine kinase TRCS [Mycobacterium tuberculosis KZN R506] gi|313657875|ref|ZP_07814755.1| two component sensor histidine kinase TRCS [Mycobacterium tuberculosis KZN V2475] Length=486 Score = 968 bits (2503), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/486 (99%), Positives = 486/486 (100%), Gaps = 0/486 (0%) Query 24 LLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT 83 +LLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT Sbjct 1 MLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT 60 Query 84 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGP 143 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGP Sbjct 61 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGP 120 Query 144 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV 203 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV Sbjct 121 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV 180 Query 204 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN 263 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN Sbjct 181 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN 240 Query 264 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES 323 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES Sbjct 241 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES 300 Query 324 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV 383 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV Sbjct 301 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV 360 Query 384 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE 443 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE Sbjct 361 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE 420 Query 444 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ 503 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ Sbjct 421 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ 480 Query 504 QIATTA 509 QIATTA Sbjct 481 QIATTA 486 >gi|254550018|ref|ZP_05140465.1| two component sensor histidine kinase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=486 Score = 967 bits (2499), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 485/486 (99%), Gaps = 0/486 (0%) Query 24 LLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT 83 +LLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT Sbjct 1 MLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPT 60 Query 84 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGP 143 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIE QVWDGGP Sbjct 61 GNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEGQVWDGGP 120 Query 144 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV 203 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV Sbjct 121 PRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTV 180 Query 204 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN 263 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN Sbjct 181 WVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDN 240 Query 264 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES 323 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES Sbjct 241 VDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIES 300 Query 324 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV 383 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV Sbjct 301 EARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV 360 Query 384 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE 443 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE Sbjct 361 WVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPE 420 Query 444 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ 503 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ Sbjct 421 ILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ 480 Query 504 QIATTA 509 QIATTA Sbjct 481 QIATTA 486 >gi|183984427|ref|YP_001852718.1| two-component sensor histidine kinase TrcS [Mycobacterium marinum M] gi|183177753|gb|ACC42863.1| two-component sensor histidine kinase TrcS [Mycobacterium marinum M] Length=514 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/503 (80%), Positives = 436/503 (87%), Gaps = 0/503 (0%) Query 7 TRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHAL 66 T R P W PRSLR QLLLGVLAVVT+VLVAVG VSVLSL GYVTAMNDAE+VES+HA Sbjct 2 TGHRNTPRWLPRSLRWQLLLGVLAVVTIVLVAVGGVSVLSLRGYVTAMNDAEVVESMHAF 61 Query 67 NHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPA 126 +H+Y RYR+ TS TG P+SQA+LEFTGQTPGNLIAV+ DGVVIGSAVFSED RPA Sbjct 62 SHAYARYRNGEHTSIHTGTPPVSQALLEFTGQTPGNLIAVVRDGVVIGSAVFSEDAPRPA 121 Query 127 PPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVT 186 PPDVI AIE Q W P RVE+LGSLG+YQVDS AAG+DRL VGVSLS+A++II RK++T Sbjct 122 PPDVIHAIETQHWTDEPSRVETLGSLGSYQVDSRAAGSDRLIVGVSLSIADRIITRKQIT 181 Query 187 TVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDP 246 T LV ALV+TAALTVWVVG LRPLRRVAATAA VA MPL DDHQISVRVRP DTDP Sbjct 182 TSVLVATALVITAALTVWVVGITLRPLRRVAATAATVAAMPLAGDDHQISVRVRPEDTDP 241 Query 247 DNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQD 306 DNEVGIVGHTLNRLLDNVD AL HRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQD Sbjct 242 DNEVGIVGHTLNRLLDNVDSALQHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQD 301 Query 307 SSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAA 366 SSDLPPTTEYALARIESEARRM LVDELLLLSRL EGEDLETE LDLTDLV+NAVNDAA Sbjct 302 SSDLPPTTEYALARIESEARRMASLVDELLLLSRLGEGEDLETEHLDLTDLVMNAVNDAA 361 Query 367 VAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNA 426 VAAPTHRW+K+LPDEPVW+NGDHARLHQLVSNLLTNAWVHT PGVTV GIT + P+ Sbjct 362 VAAPTHRWIKDLPDEPVWINGDHARLHQLVSNLLTNAWVHTPPGVTVKTGITSYPDDPSG 421 Query 427 PCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAE 486 P EL+V++DGPDIDPE+LPHLF+RFVR+SKSRS+ GHGLGLAIV+SIVKAH GSVTAE Sbjct 422 PYTELTVSNDGPDIDPEVLPHLFERFVRSSKSRSSAPGHGLGLAIVNSIVKAHDGSVTAE 481 Query 487 SGNGQTVFRVRLPMIEQQIATTA 509 S GQTVFR+RLP+I+ + +A Sbjct 482 SAAGQTVFRIRLPLIDAPLNASA 504 >gi|118619707|ref|YP_908039.1| two component sensor histidine kinase TrcS [Mycobacterium ulcerans Agy99] gi|118571817|gb|ABL06568.1| two component sensor histidine kinase TrcS [Mycobacterium ulcerans Agy99] Length=500 Score = 739 bits (1907), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/490 (80%), Positives = 428/490 (88%), Gaps = 0/490 (0%) Query 20 LRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQT 79 +R QLLLGVLAVVT+VLVAVG VSVLSL GYVTAMNDAE+VES+HA +H+Y RYR+ T Sbjct 1 MRWQLLLGVLAVVTIVLVAVGGVSVLSLRGYVTAMNDAEVVESMHAFSHAYARYRNGEHT 60 Query 80 STPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVW 139 S TG P+SQA+LEFTGQTPGNLIAV+ DGVVIGSAVFSED RPAPPDVI AIE Q W Sbjct 61 SIHTGTPPLSQALLEFTGQTPGNLIAVMRDGVVIGSAVFSEDAPRPAPPDVIHAIETQHW 120 Query 140 DGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTA 199 P RVE+LGSLG+YQVDS AAG+DRL VGVSLS+A++II RK++TT LV ALV+TA Sbjct 121 TDEPSRVETLGSLGSYQVDSRAAGSDRLIVGVSLSIADRIITRKQITTSVLVATALVITA 180 Query 200 ALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNR 259 ALTVWVVG LRPLRRVAATAA VA MPL DDHQISVRVRP DTDPDNEVGIVGHTLNR Sbjct 181 ALTVWVVGITLRPLRRVAATAATVAAMPLAGDDHQISVRVRPEDTDPDNEVGIVGHTLNR 240 Query 260 LLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALA 319 LLDNVD AL HRV SDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALA Sbjct 241 LLDNVDSALQHRVASDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALA 300 Query 320 RIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLP 379 RIESEARRM LVDELLLLSRL EGEDLETE LDLTDLV+NAVNDAAVAAPTHRW+K+LP Sbjct 301 RIESEARRMASLVDELLLLSRLGEGEDLETEHLDLTDLVMNAVNDAAVAAPTHRWIKDLP 360 Query 380 DEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPD 439 DEPVWVNGDHARLHQLVSNLLTNAWVHT PGVTV GIT + PN P EL+V++DGPD Sbjct 361 DEPVWVNGDHARLHQLVSNLLTNAWVHTPPGVTVKTGITNYPDDPNGPYTELTVSNDGPD 420 Query 440 IDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 IDPE+LPHLF+RFVR+SKSRS+ GHGLGLAIV+SIVKAH GSVTAES GQTVFR+RLP Sbjct 421 IDPEVLPHLFERFVRSSKSRSSAPGHGLGLAIVNSIVKAHDGSVTAESAAGQTVFRIRLP 480 Query 500 MIEQQIATTA 509 +I+ + +A Sbjct 481 LIDAPLNASA 490 >gi|240169875|ref|ZP_04748534.1| two-component sensor histidine kinase TrcS [Mycobacterium kansasii ATCC 12478] Length=504 Score = 721 bits (1862), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/503 (79%), Positives = 431/503 (86%), Gaps = 5/503 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M DRNT P W PRSLR QLLLGVLAVVTVVLVAVG VSVLSL GYVTAMNDAE+ Sbjct 1 MTGDRNT-----PRWFPRSLRGQLLLGVLAVVTVVLVAVGAVSVLSLRGYVTAMNDAEVA 55 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESLHAL+H+Y RYR+ TS TG P+SQA+LEFTGQTPGNLIAVL DGVVIGSAVFSE Sbjct 56 ESLHALSHAYARYRNGEHTSIHTGTPPVSQALLEFTGQTPGNLIAVLRDGVVIGSAVFSE 115 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 D +PAP DVIRAIE Q WD GP RVE+LGSLG+YQV S AAG+DRL VGVSL+LA+QII Sbjct 116 DEPQPAPADVIRAIEVQSWDDGPARVETLGSLGSYQVASRAAGSDRLIVGVSLNLADQII 175 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 +RK +TT LV ALV+TA LT WVVGYALRPLRR+AATAAEVA +PL +DH+I VRVR Sbjct 176 SRKNITTTVLVATALVITAVLTAWVVGYALRPLRRLAATAAEVAALPLAGEDHRIGVRVR 235 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DTDPDNEVGIVGHTLNRLLDNVD AL HRV+SDLRMRQFITDASHELRTPLAAIQGYA Sbjct 236 PEDTDPDNEVGIVGHTLNRLLDNVDSALQHRVESDLRMRQFITDASHELRTPLAAIQGYA 295 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS LPPTTEYALARIESEARRM LVDELLLLSRL EGEDL+TE+LDLTDLV+N Sbjct 296 ELTRQDSSALPPTTEYALARIESEARRMASLVDELLLLSRLGEGEDLQTEELDLTDLVMN 355 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDA VAAP+H WVK LPDEPVWVNGDHARLHQLVSNLLTNAWVHT PGVTVT ITCH Sbjct 356 AVNDATVAAPSHCWVKELPDEPVWVNGDHARLHQLVSNLLTNAWVHTPPGVTVTTAITCH 415 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 N EL+V+DDGP IDP+++P LF+RFVRA+ +RS +GHGLGLAIV+SIVKAH Sbjct 416 TDATNGSYAELTVSDDGPGIDPDVVPQLFERFVRANTTRSGEAGHGLGLAIVNSIVKAHD 475 Query 481 GSVTAESGNGQTVFRVRLPMIEQ 503 GSVTAES +G TVFRVRLPM+++ Sbjct 476 GSVTAESAHGHTVFRVRLPMMDR 498 >gi|41407099|ref|NP_959935.1| hypothetical protein MAP1001c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395450|gb|AAS03318.1| hypothetical protein MAP_1001c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461320|gb|EGO40191.1| signal transduction histidine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=512 Score = 679 bits (1752), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/501 (74%), Positives = 416/501 (84%), Gaps = 0/501 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M DR+T S P W P SLR+QLL GVLAVV+VVLV VG VSVLSL GYV AM+DA++ Sbjct 1 MTRDRDTASGGFPRWFPSSLRRQLLFGVLAVVSVVLVTVGFVSVLSLRGYVNAMSDADVA 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESL A +H YT+YR+ S G P+ QA+LEFTGQTPGNLIAVL +G VIGSAVFSE Sbjct 61 ESLDAFSHQYTKYRNGEHVSPHPGTPPIQQAILEFTGQTPGNLIAVLRNGAVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 D RPAPPDV+R + AQ W PPR E LG LG Y+V+S+ G+D L VGVS +LA++II Sbjct 121 DEPRPAPPDVVRDLAAQSWKDSPPRTEILGRLGPYRVNSTVNGSDVLVVGVSHNLADRII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARK++TTVAL +AL++TA LTVWVVGY LRPLRR+AA AA VA MPLTDDDH+I+VRV+ Sbjct 181 ARKQLTTVALTASALLLTAGLTVWVVGYTLRPLRRLAAIAAHVAAMPLTDDDHRITVRVQ 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DTDP NEVGIVGH LNRLLDNVD ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PQDTDPQNEVGIVGHALNRLLDNVDSALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS LPPTTEYALARIESEARRM LLVDELLLLSRL EG+DL++ED+DLT++V + Sbjct 301 ELTRQDSSTLPPTTEYALARIESEARRMALLVDELLLLSRLGEGQDLQSEDVDLTEVVSD 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDA VAAPTH WVK+LPDEPVWV GD ARLHQLVSNLL NA VHT PGVTVT I CH Sbjct 361 AVNDAMVAAPTHHWVKDLPDEPVWVRGDQARLHQLVSNLLGNARVHTPPGVTVTTAIRCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 R G AP EL+VTDDGP ID ++LP+LF+RFVRA KSRS+GSGHGLGLAIVSSIVKAH Sbjct 421 RGGREAPFAELTVTDDGPGIDADLLPNLFERFVRADKSRSDGSGHGLGLAIVSSIVKAHH 480 Query 481 GSVTAESGNGQTVFRVRLPMI 501 GSV ES G+TVFRVRLP+I Sbjct 481 GSVGVESTAGRTVFRVRLPLI 501 >gi|118463007|ref|YP_880423.1| two component sensor histidine kinase trcs [Mycobacterium avium 104] gi|118164294|gb|ABK65191.1| two component sensor histidine kinase trcs [Mycobacterium avium 104] Length=512 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/502 (74%), Positives = 416/502 (83%), Gaps = 0/502 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M DR+T S P W P SLR+QLL GVLAVV+VVLV VG VSVLSL GYV AM+DA++ Sbjct 1 MTRDRDTASGGFPRWFPSSLRRQLLFGVLAVVSVVLVTVGFVSVLSLRGYVNAMSDADVA 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESL A +H YT+YR+ S G P+ QA+LEFTGQTPGNLIAVL +G VIGSAVFSE Sbjct 61 ESLDAFSHQYTKYRNGEHVSPHPGTPPIQQAILEFTGQTPGNLIAVLRNGAVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 D RPAPPDV+R + AQ W PPR E LG LG Y+V+S+ G+D L VGVS +LA++II Sbjct 121 DEPRPAPPDVVRDLAAQSWKDSPPRTEILGRLGPYRVNSTVNGSDVLVVGVSHNLADRII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARK++TTVAL +AL++TA LTVWVVGY LRPLRR+AA AA VA MPLTDDDH+I+VRV+ Sbjct 181 ARKQLTTVALTASALLLTAGLTVWVVGYTLRPLRRLAAIAAHVAAMPLTDDDHRITVRVQ 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DTDP NEVGIVGH LNRLLDNVD ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PQDTDPQNEVGIVGHALNRLLDNVDSALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS LPPTTEYALARIESEARRM LLVDELLLLSRL EG+DL++ED+DLT++V + Sbjct 301 ELTRQDSSALPPTTEYALARIESEARRMALLVDELLLLSRLGEGQDLQSEDVDLTEVVSD 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDA VAAP H WVK+LPDEPVWV GD ARLHQLVSNLL NA VHT PGVTVT I CH Sbjct 361 AVNDAMVAAPAHHWVKDLPDEPVWVRGDQARLHQLVSNLLGNARVHTPPGVTVTTAIRCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 R G AP EL+VTDDGP ID ++LP+LF+RFVRA KSRS+GSGHGLGLAIVSSIVKAH Sbjct 421 RGGREAPFAELTVTDDGPGIDADLLPNLFERFVRADKSRSDGSGHGLGLAIVSSIVKAHH 480 Query 481 GSVTAESGNGQTVFRVRLPMIE 502 GSV ES G+TVFRVRLP+I+ Sbjct 481 GSVGVESTAGRTVFRVRLPLID 502 >gi|254774012|ref|ZP_05215528.1| two component sensor histidine kinase trcs [Mycobacterium avium subsp. avium ATCC 25291] Length=512 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/502 (74%), Positives = 415/502 (83%), Gaps = 0/502 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M DR+T S P W P SLR+QLL GVLAVV+VVLV VG VSVLSL GYV AM+DA+ Sbjct 1 MTRDRDTASGGFPRWFPSSLRRQLLFGVLAVVSVVLVTVGFVSVLSLRGYVNAMSDADAA 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESL A +H YT+YR+ S G P+ QA+LEFTGQTPGNLIAVL +G VIGSAVFSE Sbjct 61 ESLDAFSHQYTKYRNGEHVSPHPGTPPIQQAILEFTGQTPGNLIAVLRNGAVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 D RPAPPDV+R + AQ W PPR E LG LG Y+V+S+ G+D L VGVS +LA++II Sbjct 121 DEPRPAPPDVVRDLAAQSWKDSPPRTEILGRLGPYRVNSTVNGSDVLVVGVSHNLADRII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARK++TTVAL +AL++TA LTVWVVGY LRPLRR+AA AA VA MPLTDDDH+I+VRV+ Sbjct 181 ARKQLTTVALTASALLLTAGLTVWVVGYTLRPLRRLAAIAAHVAAMPLTDDDHRITVRVQ 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DTDP NEVGIVGH LNRLLDNVD ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA Sbjct 241 PQDTDPQNEVGIVGHALNRLLDNVDSALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS LPPTTEYALARIESEARRM LLVDELLLLSRL EG+DL++ED+DLT++V + Sbjct 301 ELTRQDSSALPPTTEYALARIESEARRMALLVDELLLLSRLGEGQDLQSEDVDLTEVVSD 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDA VAAP H WVK+LPDEPVWV GD ARLHQLVSNLL NA VHT PGVTVT I CH Sbjct 361 AVNDAMVAAPAHHWVKDLPDEPVWVRGDQARLHQLVSNLLGNARVHTPPGVTVTTAIRCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 R G AP EL+VTDDGP ID ++LP+LF+RFVRA KSRS+GSGHGLGLAIVSSIVKAH Sbjct 421 RGGREAPFAELTVTDDGPGIDADLLPNLFERFVRADKSRSDGSGHGLGLAIVSSIVKAHH 480 Query 481 GSVTAESGNGQTVFRVRLPMIE 502 GSV ES G+TVFRVRLP+I+ Sbjct 481 GSVGVESTAGRTVFRVRLPLID 502 >gi|296169905|ref|ZP_06851517.1| sensor histidine kinase TcrS [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895461|gb|EFG75163.1| sensor histidine kinase TcrS [Mycobacterium parascrofulaceum ATCC BAA-614] Length=515 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/502 (73%), Positives = 415/502 (83%), Gaps = 1/502 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M DR+ S P W PRSLR+QLLLGVLAVV+VVL+ VG VSVLSL GYVTAM+DA++ Sbjct 1 MTRDRDALSGDLPRWLPRSLRRQLLLGVLAVVSVVLMTVGFVSVLSLRGYVTAMSDADVA 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESL AL +SY ++R + + + P+ +A+L+FT QTPGNLI VL DG VIGSAVFSE Sbjct 61 ESLDALGNSYLKFR-TGEPNPDADAKPLGRAMLQFTDQTPGNLIVVLRDGAVIGSAVFSE 119 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 ARPAP DV+ IEAQ W G PR E+LGSLG Y+V S G+D L GVSL+LA++II Sbjct 120 AEARPAPADVVHTIEAQSWTDGRPRTENLGSLGFYRVKSHVNGSDVLIAGVSLNLADRII 179 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARK+VTT L+ AALV+TA LTVWVVGY LRPLRR+A AAEVA MPLTDDDH+ISVRVR Sbjct 180 ARKQVTTTLLIAAALVITAGLTVWVVGYTLRPLRRLAGIAAEVAAMPLTDDDHRISVRVR 239 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DT+ NEVGIVGHTLNRLLDNVD ALA R +SDLRMRQFITDASHELRTPLAAIQGYA Sbjct 240 PRDTNQQNEVGIVGHTLNRLLDNVDSALAQRAESDLRMRQFITDASHELRTPLAAIQGYA 299 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS+LPPTTEYALARIESEARRM LLVDELLLLSRL EG+DL++ED+DL +LV+N Sbjct 300 ELTRQDSSELPPTTEYALARIESEARRMALLVDELLLLSRLGEGQDLQSEDVDLAELVVN 359 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDAAVAAPTH WVK+LPDEPVWV GD RLHQLVSNLL NAWVH PGVTVT GITCH Sbjct 360 AVNDAAVAAPTHHWVKDLPDEPVWVRGDQDRLHQLVSNLLNNAWVHNPPGVTVTTGITCH 419 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 R GP+AP VEL+V DDGP IDP +LP LF+RF RA SR NG+G GLGLAIV+SIVKAH Sbjct 420 RDGPDAPWVELTVADDGPGIDPALLPRLFERFARADNSRLNGTGTGLGLAIVNSIVKAHH 479 Query 481 GSVTAESGNGQTVFRVRLPMIE 502 GSVTAES + +TVFRVR+PMI+ Sbjct 480 GSVTAESSDERTVFRVRMPMID 501 >gi|254820269|ref|ZP_05225270.1| two component sensor histidine kinase trcs [Mycobacterium intracellulare ATCC 13950] Length=511 Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/502 (74%), Positives = 417/502 (84%), Gaps = 0/502 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M D+ S P W P SLR+QLLLGVLAVV+VVLV VG+VSVLSL GYV AM+DA++ Sbjct 1 MTEDKAATSGIFPRWFPSSLRRQLLLGVLAVVSVVLVTVGIVSVLSLRGYVNAMSDADIA 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESL A +H YT+YR+ ST G P+ QA+LEFTGQTPGNLIAVL +GVVIGSAVFSE Sbjct 61 ESLDAFSHQYTKYRNGEHASTHPGTPPIGQAMLEFTGQTPGNLIAVLRNGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 +PAP DVI A+E Q W GGPPR E LG LG+Y++DS+ G+D L VG+S +LA++II Sbjct 121 GEPKPAPADVISALEGQTWSGGPPRTEILGRLGSYRLDSTVDGSDVLVVGMSQNLADRII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARK++TT+AL AL +TAALT WVVGY LRPLRR+ A AA VA MPL DDDH+IS+RV+ Sbjct 181 ARKQITTIALTAGALALTAALTGWVVGYTLRPLRRLGAIAANVAAMPLADDDHRISIRVQ 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYA 300 P DTDP NEVGIVGHTLNRLLDNVDGALAHRV+SDLRMRQFI+DASHELRTPLAAIQGYA Sbjct 241 PQDTDPQNEVGIVGHTLNRLLDNVDGALAHRVESDLRMRQFISDASHELRTPLAAIQGYA 300 Query 301 ELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 ELTRQDSS+LPPTTEYALARIESEARRM LLVDELLLLSRL EG+DL++ED+DL + N Sbjct 301 ELTRQDSSELPPTTEYALARIESEARRMALLVDELLLLSRLGEGQDLQSEDVDLAAVANN 360 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCH 420 AVNDA VAA TH WVK+LPD PVWV GDHARLHQLVSNLL NA VHT PGVTVT GITCH Sbjct 361 AVNDATVAALTHHWVKDLPDHPVWVRGDHARLHQLVSNLLGNARVHTPPGVTVTTGITCH 420 Query 421 RTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHR 480 R GP +P VEL+VTDDGP ID E+LP LF+RFVRA KSRS+GSGHGLGL IVSSIVKAH Sbjct 421 RDGPESPFVELTVTDDGPGIDEELLPRLFERFVRADKSRSDGSGHGLGLPIVSSIVKAHH 480 Query 481 GSVTAESGNGQTVFRVRLPMIE 502 GSVT ES +TVFRVRLP+I+ Sbjct 481 GSVTVESTEDETVFRVRLPLID 502 >gi|342861636|ref|ZP_08718282.1| two component sensor histidine kinase TRCS [Mycobacterium colombiense CECT 3035] gi|342130770|gb|EGT84066.1| two component sensor histidine kinase TRCS [Mycobacterium colombiense CECT 3035] Length=482 Score = 657 bits (1695), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/476 (76%), Positives = 408/476 (86%), Gaps = 0/476 (0%) Query 28 VLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPTGNLP 87 +LAVV+VVLV VG+VSVLSL GYV AM+DA++ ESL AL+H Y +YR+ S+ G+ P Sbjct 1 MLAVVSVVLVTVGIVSVLSLRGYVNAMSDADVAESLDALSHQYAKYRNGEHVSSRPGSPP 60 Query 88 MSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVE 147 ++QA+LEFTGQTPGNLIAVLH+G VIGSAVFSED +PAP DV+R ++AQ W GPPR E Sbjct 61 IAQAMLEFTGQTPGNLIAVLHNGTVIGSAVFSEDEPKPAPADVVRDLQAQTWSDGPPRTE 120 Query 148 SLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVG 207 +LG LG Y++DS+ AG+D L VG S +LA++IIARK+VTT+ L AAL +TAALTVWVVG Sbjct 121 TLGRLGPYRIDSTVAGSDVLVVGTSQNLADRIIARKQVTTIGLTAAALALTAALTVWVVG 180 Query 208 YALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGA 267 Y LRPLRR+AA AA+VA MPLT D+H+IS RV P DTDP NEVGIVGHTLNRLLDNVD A Sbjct 181 YTLRPLRRLAAVAADVAAMPLTGDEHRISARVPPQDTDPQNEVGIVGHTLNRLLDNVDSA 240 Query 268 LAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARR 327 LAHRV+SDLRMRQFITDASHELRTPLAAIQGYAELTRQDSS LPPTTEYALARIESEARR Sbjct 241 LAHRVESDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSALPPTTEYALARIESEARR 300 Query 328 MTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNG 387 M LLVDELLLLSRL EG+DLE+ED+DL ++V NAVNDA VAA TH+WVK+LPDEPVWV G Sbjct 301 MALLVDELLLLSRLGEGQDLESEDVDLAEVVGNAVNDATVAASTHQWVKDLPDEPVWVRG 360 Query 388 DHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPH 447 DHARLHQLVSNLL+NA VHT PGVTVT GITCHR P+ P EL+V DDGP IDPEILP+ Sbjct 361 DHARLHQLVSNLLSNARVHTPPGVTVTTGITCHRGAPDGPFAELTVIDDGPGIDPEILPN 420 Query 448 LFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQ 503 LF RFVRA KSRS+GSGHGLGLAIVSSIVKAHRGSVTAES TVFRVRLP+I + Sbjct 421 LFGRFVRADKSRSDGSGHGLGLAIVSSIVKAHRGSVTAESNENCTVFRVRLPLISR 476 >gi|289753094|ref|ZP_06512472.1| LOW QUALITY PROTEIN: two component sensor histidine kinase trcs [Mycobacterium tuberculosis EAS054] gi|289693681|gb|EFD61110.1| LOW QUALITY PROTEIN: two component sensor histidine kinase trcs [Mycobacterium tuberculosis EAS054] Length=351 Score = 612 bits (1578), Expect = 4e-173, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%), Gaps = 0/303 (0%) Query 207 GYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDG 266 GYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDG Sbjct 49 GYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDG 108 Query 267 ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEAR 326 ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEAR Sbjct 109 ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEAR 168 Query 327 RMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVN 386 RMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVN Sbjct 169 RMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVN 228 Query 387 GDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILP 446 GDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILP Sbjct 229 GDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILP 288 Query 447 HLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIA 506 HLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIA Sbjct 289 HLFDRFVRASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIA 348 Query 507 TTA 509 TTA Sbjct 349 TTA 351 >gi|253799936|ref|YP_003032937.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis KZN 1435] gi|253321439|gb|ACT26042.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis KZN 1435] Length=301 Score = 579 bits (1493), Expect = 3e-163, Method: Compositional matrix adjust. Identities = 292/292 (100%), Positives = 292/292 (100%), Gaps = 0/292 (0%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV Sbjct 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE Sbjct 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE 120 Query 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII Sbjct 121 DGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQII 180 Query 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR Sbjct 181 ARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVR 240 Query 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTP 292 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTP Sbjct 241 PGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTP 292 >gi|333992568|ref|YP_004525182.1| two-component sensor histidine kinase [Mycobacterium sp. JDM601] gi|333488536|gb|AEF37928.1| two-component sensor histidine kinase TrcS [Mycobacterium sp. JDM601] Length=497 Score = 487 bits (1253), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 287/460 (63%), Positives = 343/460 (75%), Gaps = 2/460 (0%) Query 45 LSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLI 104 LSL YVTA +DA+L ESL+A +HS+ +YR + + + A+L F+ QTPGN++ Sbjct 21 LSLRNYVTATSDADLSESLNAFSHSFAKYRRAQNVAGADEASTIGPAMLGFSDQTPGNVL 80 Query 105 AVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGA 164 AVL +G VIGSAVF+ PAP DV+ AI+A W GPP+ LGSLG Y+V++ Sbjct 81 AVLRNGKVIGSAVFTVADPYPAPADVVAAIDAHHWHNGPPQTMDLGSLGTYRVETRVVDQ 140 Query 165 DRL-FVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEV 223 D L F+G SL+LAN+ + R+ L AL++TA LT+ VV YALRPLRRVAATA V Sbjct 141 DDLLFIGGSLNLANRTVVRRMAAAATLYTLALLITAGLTITVVNYALRPLRRVAATAGAV 200 Query 224 ATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFIT 283 A MPLTD D +I+VRV D DPDNEVGIV LNRLLDNVD ALA+R ++D RMRQFIT Sbjct 201 AAMPLTDGDERITVRVSEDDVDPDNEVGIVAGALNRLLDNVDSALAYRSEADRRMRQFIT 260 Query 284 DASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSE 343 DASHELRTPLAAIQGYAELTRQDS+ LPPTTEYALARIESEA+RM LV+ELLLLSRL E Sbjct 261 DASHELRTPLAAIQGYAELTRQDSATLPPTTEYALARIESEAQRMASLVEELLLLSRLGE 320 Query 344 GEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNA 403 G+DL ED+DL DLV +AVNDAA AA +H WVK LP+ PVWV GD ARLHQ+V+NLL NA Sbjct 321 GQDLNIEDVDLADLVADAVNDAAAAAASHHWVKELPESPVWVRGDRARLHQVVTNLLKNA 380 Query 404 WVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGS 463 WVHT GVTVT I R P EL+V +DGP I+ +++PHLF+RFVRA K+RS S Sbjct 381 WVHTPAGVTVTTAIAADRARVGGPVAELTVANDGPAIEADMVPHLFERFVRADKARSGES 440 Query 464 GH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPMIE 502 G GLGLAIV+SIV AHRGSV AES +G TVFRVRLPM++ Sbjct 441 GSTGLGLAIVASIVGAHRGSVDAESSDGATVFRVRLPMVD 480 >gi|253799937|ref|YP_003032938.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis KZN 1435] gi|253321440|gb|ACT26043.1| two component system sensor histidine kinase trcS [Mycobacterium tuberculosis KZN 1435] Length=217 Score = 442 bits (1137), Expect = 7e-122, Method: Compositional matrix adjust. Identities = 216/217 (99%), Positives = 217/217 (100%), Gaps = 0/217 (0%) Query 293 LAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDL 352 +AAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDL Sbjct 1 MAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDL 60 Query 353 DLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVT 412 DLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVT Sbjct 61 DLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVT 120 Query 413 VTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIV 472 VTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIV Sbjct 121 VTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGHGLGLAIV 180 Query 473 SSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIATTA 509 SSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIATTA Sbjct 181 SSIVKAHRGSVTAESGNGQTVFRVRLPMIEQQIATTA 217 >gi|118469988|ref|YP_887234.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155] gi|118171275|gb|ABK72171.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155] Length=502 Score = 431 bits (1109), Expect = 1e-118, Method: Compositional matrix adjust. Identities = 251/498 (51%), Positives = 338/498 (68%), Gaps = 13/498 (2%) Query 10 RKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHS 69 R W SLR+QL++GV AVV + L +G +SV +L + + DA+L + + + Sbjct 2 RTPKSW---SLRRQLVVGVSAVVMIALATIGTLSVFTLRSSMVGLIDAQLAGAADGFSKT 58 Query 70 YTRYRDS----AQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARP 125 T+YR + P G++ + ++ GQ GN+IA++ DG V+ SA FS+ A+ Sbjct 59 VTKYRTTPLPGEDEVPPPGSM---KPLIHVLGQAEGNVIALIQDGEVVDSAFFSDGDAQA 115 Query 126 APPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAA-GADRLFVGVSLSLANQIIARKK 184 APP + + G PR + LG Y+V S G + L VS + A + + R Sbjct 116 APPAAVDTLRDLATTGPTPRNVDIPGLGWYRVVSHPGDGDESLVTAVSYTPAWEAMMRVT 175 Query 185 VTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDT 244 A+ AL++TA T+ +VG+ALRPLRRVAATAAEVAT+PL ++H I+ RV DT Sbjct 176 GIVSAMTVVALILTAISTIAIVGFALRPLRRVAATAAEVATLPLDRENHAITPRVPACDT 235 Query 245 DPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTR 304 DP EVG VG TLN+LLD+V+ ALA SD RMRQFITDASHELRTPLAAI GYAELTR Sbjct 236 DPRTEVGRVGDTLNQLLDHVERALADVAASDRRMRQFITDASHELRTPLAAIHGYAELTR 295 Query 305 QDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVND 364 QDSS LP TTEY+LARIE+EA+RM LV +LLLL+RL EG++L+T ++DLT+LV +AVND Sbjct 296 QDSSVLPETTEYSLARIEAEAQRMNSLVSDLLLLARLDEGQELDTTEVDLTELVADAVND 355 Query 365 AAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGP 424 AAV+APTH W +PD+PVWV DHARLHQ ++NLL+NA VHT G +V + H G Sbjct 356 AAVSAPTHHWSVRVPDDPVWVRADHARLHQTLANLLSNARVHTPEGTSVQTTLVVHGNG- 414 Query 425 NAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSG-HGLGLAIVSSIVKAHRGSV 483 + E++V+D+GP I+P++LPHLF+RFVRA KSRS +G GLGL+I +SIV+AH G++ Sbjct 415 DTSHAEVTVSDNGPGINPDLLPHLFERFVRADKSRSRAAGSFGLGLSIAASIVEAHGGTI 474 Query 484 TAESGNGQTVFRVRLPMI 501 +A+SG+G+T F +RLP I Sbjct 475 SAQSGSGKTSFVIRLPSI 492 >gi|120403286|ref|YP_953115.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium vanbaalenii PYR-1] gi|119956104|gb|ABM13109.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium vanbaalenii PYR-1] Length=502 Score = 423 bits (1088), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 260/491 (53%), Positives = 335/491 (69%), Gaps = 8/491 (1%) Query 14 CWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRY 73 W+ +L +QL++GV VV V LV+VG ++V++L V + D +L + A S +Y Sbjct 3 AWKSWTLLRQLVVGVSVVVMVALVSVGAMTVMTLRSSVLGIIDTQLSVAADATISSVAKY 62 Query 74 RDSAQTSTPTGNLPMSQAVLEFT---GQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDV 130 R T P G +P A+ T GQ PGN++ ++ +G V+ SA F + A+ AP Sbjct 63 R---STPGPGGQMPAPGAMKPLTHLIGQAPGNIVVLIQNGEVVDSAFFGDGDAQVAPAAA 119 Query 131 IRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFV-GVSLSLANQIIARKKVTTVA 189 + I Q W PR L LG Y+++S A D + V GVS + A ++ R+ Sbjct 120 VETIADQSWTDPQPRTVELPGLGWYRMESRAGDGDEVLVTGVSRTPAWNVMVRETAIVSG 179 Query 190 LVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNE 249 + ALVVTA TV +V +ALRPLRRVAATAAEVA +PL D+H I+ RV GDTDP E Sbjct 180 ITAIALVVTALSTVAIVRFALRPLRRVAATAAEVAGLPLDRDNHAITPRVPAGDTDPSTE 239 Query 250 VGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSD 309 VG+VG TLNRLLD+V+ ALA SD RMRQFITDASHELRTPLAAI GYAELTRQDSS Sbjct 240 VGLVGDTLNRLLDHVEHALADVAASDRRMRQFITDASHELRTPLAAIHGYAELTRQDSSV 299 Query 310 LPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAA 369 LP TTEY+LARIE+EA+RM LV +LLLL+RL EG+D +T ++DL DLV++AVNDA V A Sbjct 300 LPQTTEYSLARIEAEAQRMHALVADLLLLARLDEGQDRQTTEVDLADLVVDAVNDATVCA 359 Query 370 PTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCV 429 P HRW+ ++PDE V V GD A+LHQ+++NLL+NA VHT G TVT ++ V Sbjct 360 PEHRWLTSVPDELVNVLGDRAQLHQMLANLLSNARVHTPAGTTVTTTVSKGTAADGTGYV 419 Query 430 ELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSG-HGLGLAIVSSIVKAHRGSVTAESG 488 EL+VTDDGP IDP++LPHLF+RFVRA +SRS +G GLGLAIV+SIV++H G++ A SG Sbjct 420 ELTVTDDGPGIDPQLLPHLFERFVRADRSRSRQNGSFGLGLAIVASIVESHGGTIDATSG 479 Query 489 NGQTVFRVRLP 499 +G T FRVRLP Sbjct 480 SGTTAFRVRLP 490 >gi|324999381|ref|ZP_08120493.1| integral membrane sensor signal transduction histidine kinase [Pseudonocardia sp. P1] Length=508 Score = 320 bits (820), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 217/509 (43%), Positives = 291/509 (58%), Gaps = 32/509 (6%) Query 14 CWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYT-- 71 R RSLR +L++ VL V TV VA+GV + LSL Y+++ D ELV +L T Sbjct 7 SGRVRSLRARLVITVLLVFTVACVAIGVTTTLSLDRYLSSRQDRELVLALDGFVSRQTGQ 66 Query 72 -----------RYRDSAQTSTP-TGNLPM----SQAVLEFTGQTPGNLIAVLHDGVVIGS 115 R A + P G P+ L GQ PG++ AV G V + Sbjct 67 PPGSVADPGGDRTAPDAGSGAPGPGRSPLPAVPGDGFLIGPGQGPGSMAAVFDAGRVERA 126 Query 116 AVFSEDGARPAPPDV-IRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLS 174 G + D + A++ DG P ++ S G Y+ + AG R +V Sbjct 127 ERAERGGTGTSVADTDVAALQTVPADGAP--HDTALSPGNYRAVAHVAGT-RTYVVAQPD 183 Query 175 LANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQ 234 A + + R VT V ++GAA+++ +V LRPL RVA AA V +PL + Sbjct 184 SAGETVDRLLVTEVIVLGAAVLLAGLGAAVLVRRELRPLERVAGVAAGVGALPLDRGEVH 243 Query 235 ISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLA 294 ++ RV D DP EVG VG LN +LDNV+GALA R +S+ R+R+F+ DASHELRTPLA Sbjct 244 LAARVP--DPDPRTEVGQVGTALNHMLDNVEGALAARQESETRLRRFVADASHELRTPLA 301 Query 295 AIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDL 354 AI+GYAEL+R++ +P T +AL RI S+A RM+ LV++LLLL+RL G LE ++DL Sbjct 302 AIRGYAELSRREPDPVPAGTTHALTRITSQAERMSTLVEDLLLLARLDSGRPLERTEVDL 361 Query 355 TDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVT 414 T LV++ V DA VA P HRW LPD+PV V GD RL Q+V+NLL NA HT PG +VT Sbjct 362 TRLVLDGVGDAHVAGPEHRWYPRLPDDPVTVTGDTHRLAQVVTNLLANARTHTPPGTSVT 421 Query 415 IGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH----GLGLA 470 +G+ R P V L V DDGP I PE+LP +F+RF R ++ RS GLGLA Sbjct 422 VGL--DRPAPGR--VRLRVGDDGPGIPPEVLPRVFERFARGAEGRSRAGNDTPSTGLGLA 477 Query 471 IVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 IVS++V AH G+V+ +S G+TVF V LP Sbjct 478 IVSAVVAAHDGTVSVDSEPGRTVFTVELP 506 >gi|86739036|ref|YP_479436.1| periplasmic sensor signal transduction histidine kinase [Frankia sp. CcI3] gi|86565898|gb|ABD09707.1| periplasmic sensor signal transduction histidine kinase [Frankia sp. CcI3] Length=552 Score = 303 bits (776), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 172/358 (49%), Positives = 225/358 (63%), Gaps = 7/358 (1%) Query 144 PRVESLGSLGAYQVDSSAAGADRLFV-GVSLSLANQIIARKKVTTVALVGAALVVTAALT 202 P + G G Y++ + D + V G+ + N + R + + + A Sbjct 169 PYTRAFGDQGDYRLLARTTHDDMIVVTGLPMKQVNATLTRMTMIAGVVALVGVAAAAIAG 228 Query 203 VWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLD 262 +V LRPLRRVAATA+ VA +PL + +SVRV DTDP EVG VG LNR+L Sbjct 229 TAIVRVTLRPLRRVAATASRVAELPLDRGEVALSVRVPQVDTDPRTEVGQVGAALNRMLG 288 Query 263 NVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIE 322 ++ ALA R S++RMRQF+ D SHELRTPLAAI GYAELTR+ +P YA++R+E Sbjct 289 HIGAALAARHASEMRMRQFLADVSHELRTPLAAISGYAELTRRTREHVPADVTYAMSRVE 348 Query 323 SEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEP 382 SE+ RMT LV +LLLL+RL G DL E +D++ L++NAVNDA VAAP HR+ +LP+EP Sbjct 349 SESARMTALVSDLLLLARLDSGRDLVREPVDVSRLIVNAVNDAHVAAPGHRFALDLPEEP 408 Query 383 VWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDP 442 V V GD ARLHQ+++NLL NA HT PG VT +T + P L+V DDGP I P Sbjct 409 VTVTGDPARLHQVLANLLANARTHTPPGTQVTASLTV-----SGPTAILAVVDDGPGIPP 463 Query 443 EILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 ++LP +F RF R SRS +G GLGLAIV+++V+AH G V A S G+T F V LP Sbjct 464 DLLPEVFQRFARGDSSRSRAAGSTGLGLAIVAAVVEAHHGHVRATSEPGRTAFMVELP 521 >gi|145594663|ref|YP_001158960.1| ATPase domain-containing protein [Salinispora tropica CNB-440] gi|145304000|gb|ABP54582.1| ATP-binding region, ATPase domain protein domain protein [Salinispora tropica CNB-440] Length=483 Score = 302 bits (773), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 199/485 (42%), Positives = 282/485 (59%), Gaps = 22/485 (4%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 SL +L++ ++ ++ VV + +G ++ ++L ++T D +L R + Sbjct 11 SLWTRLVVILVTLLAVVSLGIGGITTVALRDFLTDRIDRQL------------RLDAGPR 58 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSE--DGARPAPPDVIRAIEA 136 + P P + G G+++A L DG V+ + V +E +G P+ + A+ + Sbjct 59 SFVPPPPRPTQDDLQVSRGMEVGSVVAQLRDGQVVKARVQNEAREGGERIAPEKVAALGS 118 Query 137 QVWDGGPPRVESLGSLGAYQ-VDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAAL 195 V + GP V+ LG LG Y+ + + + L+ + + R V + GA L Sbjct 119 LVPNTGPHTVD-LGDLGEYRAIARQWRDGEVTAFALPLTEVQETVMRLVVAQAGVAGAGL 177 Query 196 VVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGH 255 VV A +V LRPLRRVAATA V+ +PL + + VRV DTD EVG VG Sbjct 178 VVAGATGALLVRRTLRPLRRVAATATRVSELPLDRGEVTLPVRVPGADTDTRTEVGQVGS 237 Query 256 TLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTE 315 LNR+L +V ALA R S+ R+RQF+ DASHELRTPLAAI+GYAE+ R+ + +PP Sbjct 238 ALNRMLGHVAAALAARQASETRVRQFVADASHELRTPLAAIRGYAEVARRGRNQVPPDVA 297 Query 316 YALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWV 375 +AL R+ESE+ RMT LV++LLLL+RL G L +DL+ LV++AV+DA VA P HRW Sbjct 298 HALRRVESESTRMTGLVEDLLLLARLDSGRPLAVAPVDLSALVVDAVSDAHVAGPEHRWQ 357 Query 376 KNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTD 435 +LP++ + V GD ARLHQ+V+NLLTNA VHT G TVT + + L V D Sbjct 358 LDLPEQQIAVPGDAARLHQVVANLLTNARVHTPAGTTVTTNLAV-----ESDAAVLRVAD 412 Query 436 DGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVF 494 DGP I E+ P +F+RF RA SRS G GLGLAIV+++V AH G+V+ S G+TVF Sbjct 413 DGPGIPVELQPEVFERFARADSSRSRSQGSTGLGLAIVAAVVDAHHGTVSVRSRPGRTVF 472 Query 495 RVRLP 499 VRLP Sbjct 473 TVRLP 477 >gi|336460749|gb|EGO39637.1| signal transduction histidine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=519 Score = 301 bits (772), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 194/484 (41%), Positives = 274/484 (57%), Gaps = 9/484 (1%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 SLR +LL+G + V+ +V + + V+ L+L+ ++ D +L + Y Sbjct 32 SLRLRLLVGQIVVLALVCLGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPNHPRH 91 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQV 138 +P L+ GQ G + AV+ G + + + GAR A + Q+ Sbjct 92 EHSPYPRPGPGPRFLDAPGQPAGMVAAVVSHGKTVDAGYLTSSGARDALTSTAQTQLEQI 151 Query 139 WDGGPPRVESLGSLGAYQVDS--SAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALV 196 P +L LG Y+V + S G+D + G+S++ + + R V + AL Sbjct 152 AGSRAPVTVNLDGLGRYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALA 211 Query 197 VTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHT 256 V ++ AL PLRRVA TA EVA +PL + ++ VRVR D +P EVG +G Sbjct 212 AATIAGVVIIRRALAPLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAA 271 Query 257 LNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEY 316 LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D + Sbjct 272 LNRMLDHIADALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQ- 330 Query 317 ALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVK 376 A++R+ SE RMT LV++LLLL+RL G LE E +DL+ L ++AVNDA VA P H+W Sbjct 331 AMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWEL 390 Query 377 NLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDD 436 +LP+EPV V GD ARLHQ+++NLL NA VHT G VT ++ T P L V D+ Sbjct 391 DLPEEPVVVTGDAARLHQVLTNLLANARVHTGAGTVVTTRLS---TEPAHTV--LQVIDN 445 Query 437 GPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFR 495 GP I E+ +F+RF R SRS G GLGLAIVS++VKAH G+++ S G T F Sbjct 446 GPGIPAELQSEVFERFARGDSSRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFT 505 Query 496 VRLP 499 VRLP Sbjct 506 VRLP 509 >gi|41406358|ref|NP_959194.1| hypothetical protein MAP0260 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394706|gb|AAS02577.1| hypothetical protein MAP_0260 [Mycobacterium avium subsp. paratuberculosis K-10] Length=496 Score = 301 bits (771), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 194/484 (41%), Positives = 274/484 (57%), Gaps = 9/484 (1%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 SLR +LL+G + V+ +V + + V+ L+L+ ++ D +L + Y Sbjct 9 SLRLRLLVGQIVVLALVCLGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPNHPRH 68 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQV 138 +P L+ GQ G + AV+ G + + + GAR A + Q+ Sbjct 69 EHSPYPRPGPGPRFLDAPGQPAGMVAAVVSHGKTVDAGYLTSSGARDALTSTAQTQLEQI 128 Query 139 WDGGPPRVESLGSLGAYQVDS--SAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALV 196 P +L LG Y+V + S G+D + G+S++ + + R V + AL Sbjct 129 AGSRAPVTVNLDGLGRYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALA 188 Query 197 VTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHT 256 V ++ AL PLRRVA TA EVA +PL + ++ VRVR D +P EVG +G Sbjct 189 AATIAGVVIIRRALAPLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAA 248 Query 257 LNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEY 316 LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D + Sbjct 249 LNRMLDHIADALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQ- 307 Query 317 ALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVK 376 A++R+ SE RMT LV++LLLL+RL G LE E +DL+ L ++AVNDA VA P H+W Sbjct 308 AMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWEL 367 Query 377 NLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDD 436 +LP+EPV V GD ARLHQ+++NLL NA VHT G VT ++ T P L V D+ Sbjct 368 DLPEEPVVVTGDAARLHQVLTNLLANARVHTGAGTVVTTRLS---TEPAHTV--LQVIDN 422 Query 437 GPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFR 495 GP I E+ +F+RF R SRS G GLGLAIVS++VKAH G+++ S G T F Sbjct 423 GPGIPAELQSEVFERFARGDSSRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFT 482 Query 496 VRLP 499 VRLP Sbjct 483 VRLP 486 >gi|118466581|ref|YP_879594.1| sensor histidine kinase [Mycobacterium avium 104] gi|118167868|gb|ABK68765.1| sensor histidine kinase [Mycobacterium avium 104] Length=496 Score = 300 bits (767), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 191/484 (40%), Positives = 270/484 (56%), Gaps = 9/484 (1%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 SLR +LL+G + V+ +V + + V+ L+L+ ++ D +L + Y Sbjct 9 SLRLRLLVGQIVVLALVCLGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPNHPRH 68 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQV 138 +P L+ GQ G + AV+ G + + + G R A + Q+ Sbjct 69 EHSPYPRPGPGPRFLDAPGQPAGMVAAVVSHGKTVDAGYLTSSGTRDALTSTAQTQLEQI 128 Query 139 WDGGPPRVESLGSLGAYQVDS--SAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALV 196 P +L LG Y+V + S G+D + G+S++ + + R V + AL Sbjct 129 AGSRAPVTVNLDGLGRYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALA 188 Query 197 VTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHT 256 V ++ AL PLRRVA TA EVA +PL + ++ VRVR D +P EVG +G Sbjct 189 AATIAGVVIIRRALAPLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAA 248 Query 257 LNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEY 316 LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D + Sbjct 249 LNRMLDHIADALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQ- 307 Query 317 ALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVK 376 A++R+ SE RMT LV++LLLL+RL G LE E +DL+ L ++AVNDA VA P H+W Sbjct 308 AMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWEL 367 Query 377 NLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDD 436 +LP+EPV + GD ARLHQ+++NLL NA VHT G VT R L V D+ Sbjct 368 DLPEEPVVITGDAARLHQVLTNLLANARVHTGAGTVVTT-----RLSTEPAHTVLQVIDN 422 Query 437 GPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFR 495 GP I E+ +F+RF R SRS G GLGLAIVS++VKAH G+++ S G T F Sbjct 423 GPGIPAELQSEVFERFARGDSSRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFT 482 Query 496 VRLP 499 VRLP Sbjct 483 VRLP 486 >gi|254773314|ref|ZP_05214830.1| sensor histidine kinase [Mycobacterium avium subsp. avium ATCC 25291] Length=496 Score = 299 bits (766), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 193/484 (40%), Positives = 273/484 (57%), Gaps = 9/484 (1%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 SLR +LL+G + V+ +V + + V+ L+L+ ++ D +L + Y Sbjct 9 SLRLRLLVGQIVVLALVCLGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPNHPRH 68 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQV 138 +P L+ GQ G + AV+ G + + + G R A + Q+ Sbjct 69 EHSPYPRPGPGPRFLDAPGQPAGMVAAVVGHGKTVDAGYLTSSGTRDALTSTAQTQLEQI 128 Query 139 WDGGPPRVESLGSLGAYQVDS--SAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALV 196 P +L LG Y+V + S G+D + G+S++ + + R V + AL Sbjct 129 AGSRAPVTVNLDGLGRYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALA 188 Query 197 VTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHT 256 V ++ AL PLRRVA TA EVA +PL + ++ VRVR D +P EVG +G Sbjct 189 AATIAGVVIIRRALAPLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAA 248 Query 257 LNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEY 316 LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D + Sbjct 249 LNRMLDHIADALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQ- 307 Query 317 ALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVK 376 A++R+ SE RMT LV++LLLL+RL G LE E +DL+ L ++AVNDA VA P H+W Sbjct 308 AMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWEL 367 Query 377 NLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDD 436 +LP+EPV V GD ARLHQ+++NLL NA VHT G VT ++ T P L V D+ Sbjct 368 DLPEEPVVVTGDAARLHQVLTNLLANARVHTGAGTVVTTRLS---TEPAHTV--LQVIDN 422 Query 437 GPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFR 495 GP I E+ +F+RF R SRS G GLGLAIVS++VKAH G+++ S G T F Sbjct 423 GPGIPAELQSEVFERFARGDSSRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFT 482 Query 496 VRLP 499 VRLP Sbjct 483 VRLP 486 >gi|148273949|ref|YP_001223510.1| putative two-component system, sensor kinase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147831879|emb|CAN02849.1| putative two-component system, sensor kinase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=558 Score = 299 bits (766), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 208/512 (41%), Positives = 291/512 (57%), Gaps = 23/512 (4%) Query 8 RSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALN 67 R+R R +LR++L+L V+ ++ + + +G VS+L+L + D +L + A Sbjct 21 RARLTAAARGMTLRRRLVLSVVGLLALASILIGTVSILALRASLVQEVDQQLQAT--AAR 78 Query 68 HSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAP 127 S RD+ Q + G P L GQ G + A + DGVV G + D A Sbjct 79 SSNLIDRDADQYGSFPGAPPGG---LGAFGQQVGTISATIVDGVVSGGYIADRDAAE-GE 134 Query 128 PDVIRAIEAQVW----------DGGPPRVESLGSLGAYQV--DSSAAGADRLFVGVSLSL 175 P A+E DG P V+ G+LG Y++ D++A GA L G+ + Sbjct 135 PGGAGAVELTQVQSQQLQSVPTDGIPRTVDLGGALGRYRLVGDTAATGAT-LVTGLPMKP 193 Query 176 ANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQI 235 A+ ++ + V + L + A L +V ALRPL RV TA VA + L D + Sbjct 194 ADDVVEQLIVVISVVAALTLALAAVLGAVIVRRALRPLDRVVDTATHVAALELDRGDVAL 253 Query 236 SVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAA 295 RV DTD EVG VG LN LL +V AL+ R S+ ++R+F++DASHELRTPLA+ Sbjct 254 EARVPASDTDERTEVGRVGAALNGLLGHVAAALSSRQASEAKVRRFVSDASHELRTPLAS 313 Query 296 IQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLT 355 I+GYAELTR+ LP ++L+RIESE+ RMT +V++LLLL+RL EG +LE++ +DLT Sbjct 314 IRGYAELTRRGPHQLPEDVTHSLSRIESESVRMTTIVEDLLLLARLDEGRELESDPVDLT 373 Query 356 DLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTI 415 ++++ V DA+ A P H W +LPD+ V V GD ARL Q+V NLL NA HT G V Sbjct 374 RILLDTVGDASAAGPDHDWDLDLPDDSVSVPGDDARLRQVVVNLLANARTHTPAGTRVVA 433 Query 416 GITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVR--ASKSRSNGSGHGLGLAIVS 473 + G +A V + VTDDGP I PE+ LF+RFVR S++RS G G GLGLAI Sbjct 434 SLAVEGAGSDAHAV-IRVTDDGPGIPPELQASLFERFVRGDGSRARSTG-GTGLGLAIAQ 491 Query 474 SIVKAHRGSVTAESGNGQTVFRVRLPMIEQQI 505 +IV AH G+V ES G+TVF VRLP+ + + Sbjct 492 AIVSAHHGAVWVESEPGRTVFGVRLPVARRAV 523 >gi|183985284|ref|YP_001853575.1| two-component sensor kinase TcrY [Mycobacterium marinum M] gi|183178610|gb|ACC43720.1| two-component sensor kinase TcrY [Mycobacterium marinum M] Length=504 Score = 296 bits (759), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 201/505 (40%), Positives = 282/505 (56%), Gaps = 25/505 (4%) Query 6 NTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLH- 64 N R+ W SLR +LL+G + V+ VV V + + L+L ++ A D +L + H Sbjct 4 NRLVRRPGAW---SLRLRLLVGQILVLAVVCVGITAATELALHHHLVAQLDGQLGGTSHR 60 Query 65 -AL-----NHSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVF 118 AL +H + R++ P L+ GQ G + AV+ DG I + Sbjct 61 SALMYPESSHRFWRHQHRYWRPGPGPRF------LDAPGQPAGMVGAVVRDGKAIVAGYL 114 Query 119 SEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDS--SAAGADRLFVGVSLSLA 176 + G R +A A V P +L LG Y+V S S G + + G+S+S Sbjct 115 TNSGDRAEISPTAQAQLAAVAGSQDPVTLNLDGLGRYRVVSALSRRGDELIVTGLSMSDV 174 Query 177 NQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQIS 236 + + R + + ALV ++ AL PLRRVA TA EV +PL + ++ Sbjct 175 DATMIRMLIIFGIVTIVALVAATTAGAIIIRRALAPLRRVAQTATEVVDLPLDRGEVELP 234 Query 237 VRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAI 296 VRV D +PD EVG +G LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI Sbjct 235 VRVSETDANPDTEVGQLGSALNRMLDHIAAALSTRQASETRVRQFVADASHELRTPLAAI 294 Query 297 QGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTD 356 +GY EL Q D +A++R+ SE R+T LV++LLLL+RL G LE E +D++ Sbjct 295 RGYTELA-QRMGDDRAAVAHAMSRVGSETERITSLVEDLLLLARLDSGRPLEREPVDMSR 353 Query 357 LVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIG 416 L ++AV+DA VA P +W +LP EPV V GD ARLHQ+V+NLL NA +HT PG VT Sbjct 354 LAVDAVSDAHVAGPDQQWELDLPAEPVVVTGDAARLHQVVANLLANARIHTGPGAVVTTR 413 Query 417 ITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSI 475 ++ +GP V L V D+GP I + +F+RF R SRS G GLGLAIV+++ Sbjct 414 LS---SGPT--HVVLEVIDNGPGIPEAMQSEIFERFARGDTSRSRKGGSTGLGLAIVAAV 468 Query 476 VKAHRGSVTAESGNGQTVFRVRLPM 500 VKAH G++T S G+T F VRLP+ Sbjct 469 VKAHNGTITVNSSPGRTEFVVRLPL 493 >gi|111220169|ref|YP_710963.1| putative sensor histidine kinase [Frankia alni ACN14a] gi|111147701|emb|CAJ59358.1| Putative Sensor histidine kinase [Frankia alni ACN14a] Length=648 Score = 296 bits (758), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 188/445 (43%), Positives = 255/445 (58%), Gaps = 20/445 (4%) Query 69 SYTRYRDSAQTSTPTGNLPMSQAVLE-----------FTGQT-PGNLIAVLHDGVVIGSA 116 S TRY + T G++P++ L FTG PG L A++ G+ Sbjct 133 SGTRYGTTTSWRTTAGSVPLTAQTLYGVSAASLLDNFFTGPVEPGTLAAIIDGSGFYGAY 192 Query 117 VFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSA-AGADRLFVGVSLSL 175 + + + + A DGG LG G Y++ SS + G+ + Sbjct 193 IDTTYSLQALSAGQTATVAAVPRDGGT-HTRGLGEAGDYRLLSSTRPDGTTVVTGLPMKQ 251 Query 176 ANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQI 235 N + + A+ A + A +V LRPLRRVAATA+ VA +PL + + Sbjct 252 VNATLTKMAAIAGAVALAGVAAAALAGTVIVRVTLRPLRRVAATASRVAEIPLDRGEVAL 311 Query 236 SVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAA 295 SVRV DTDP EVG VG LNR+L ++ ALA R S+ RMRQF+ D SHELRTPLAA Sbjct 312 SVRVPDVDTDPRTEVGQVGSALNRMLGHIGAALAARHASETRMRQFLADVSHELRTPLAA 371 Query 296 IQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLT 355 I GYAELTR+ +PP YA++R+ESE+ RMT LV +LLLL+RL G LE E +D++ Sbjct 372 ISGYAELTRRTREPVPPDVTYAMSRVESESARMTALVSDLLLLARLDSGRPLEHEPVDIS 431 Query 356 DLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTI 415 +V++AV+DA VAAP HR+ +LP+EPV V GD ARLHQ+++NLL NA HT PG VT Sbjct 432 RMVVDAVSDAHVAAPDHRFALDLPEEPVTVTGDAARLHQVLANLLANARAHTPPGTRVTA 491 Query 416 GITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSS 474 + V +++ DDGP I ++LP +F+RF R SRS +G GLGLAIV++ Sbjct 492 SLAV-----TDDEVTVAIVDDGPGIPADLLPEVFERFARGDSSRSRAAGSTGLGLAIVAA 546 Query 475 IVKAHRGSVTAESGNGQTVFRVRLP 499 +V+AH+G V A S G+T F V LP Sbjct 547 VVEAHQGRVEATSQPGRTAFVVTLP 571 >gi|297158649|gb|ADI08361.1| putative two component system sensor kinase [Streptomyces bingchenggensis BCW-1] Length=575 Score = 295 bits (755), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 200/522 (39%), Positives = 282/522 (55%), Gaps = 49/522 (9%) Query 20 LRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYR----D 75 LR +L++ + ++ VV +G V+ ++L Y+ D +L + TR D Sbjct 25 LRTRLVVSAVGLIAVVCAVIGTVTTIALHTYLYDQVDKQL-------SGVATRIAGPPFD 77 Query 76 SAQTSTPTGNLPMS-QAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDV---- 130 + P G + V+ GQ G + A GV+ A+ + + P + Sbjct 78 EVKGPRPGGQWREDIRDVVAGPGQPMGTVAAEAEGGVLSEGAISRQHESSTGEPKISGSY 137 Query 131 -----IRAIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLFVGVSLSLANQIIARKKV 185 ++A+ DG V+ G G Y+V G VG+S + A + + Sbjct 138 LTAAQLKALSEVPQDGSEHTVDIPGK-GEYRVKYVVGGHGDFVVGISTAEAQNTVDTLIL 196 Query 186 TTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTD 245 +++ A LV +VG +LRPLRRVAATA V+ +PL + + RV + D Sbjct 197 AEISVTAAGLVAAGIAGAVMVGISLRPLRRVAATATRVSELPLHSGEVALHERVPMSEAD 256 Query 246 PDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQ 305 P EVG VG LNR+L +V+ ALA R +S+ R+RQF+ DASHELRTPLA+I+GYAELTR+ Sbjct 257 PRTEVGQVGAALNRMLGHVESALAARQESETRVRQFVADASHELRTPLASIRGYAELTRR 316 Query 306 DSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDA 365 ++ P T +AL R+ESEA RMT LV++LLLL+RL G +E ++DL+ +V++AV+DA Sbjct 317 GREEIGPDTRHALGRVESEAARMTGLVEDLLLLARLDAGRPVERAEVDLSPVVVDAVSDA 376 Query 366 AVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGI-------- 417 A P H+W LPD+P V GD ARL Q++ NLL NA HT PG TVT + Sbjct 377 RAAGPDHKWRLELPDDPAVVYGDDARLRQVLVNLLANARTHTPPGTTVTARVLWRGPYRA 436 Query 418 ------------------TCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSR 459 +G +APCV L V DDGP I P +LPH+F+RF R SR Sbjct 437 GHGAPYPAAPYPAPYPAPYSGFSGYSAPCVSLEVEDDGPGIPPHLLPHVFERFARGDASR 496 Query 460 SNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 S +G GLGLAIV ++V AH G VT +S G+TVF V LP+ Sbjct 497 SRAAGSTGLGLAIVHAVVTAHGGQVTVDSVPGRTVFGVHLPV 538 >gi|50954149|ref|YP_061437.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07] gi|50950631|gb|AAT88332.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07] Length=532 Score = 294 bits (752), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 196/475 (42%), Positives = 267/475 (57%), Gaps = 21/475 (4%) Query 38 AVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFTG 97 A+G VSVL+L Y+ D +L +L H+ DS ++PTG P ++ G Sbjct 34 AIGTVSVLALRTYLMQRLDGQLTSALSRGAHAA----DSLFGASPTG--PEGIRIVAAPG 87 Query 98 QTPGNLIAVLHDGVVIGSAVFSEDGA-----RPAPPDVIRAIEAQVWDGGP----PRVES 148 Q G + + + ++ A PA P V+ I P PR Sbjct 88 QPTGTFGTIRSGNQFLFPVILTDRPAGSADNHPAEPRVVGLIPGDQLRSLPADANPRTID 147 Query 149 LGS-LGAYQVDSSA-AGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVV 206 GS G Y+V + D + +G+ LS + R V + A +V L +V+ Sbjct 148 FGSAYGDYRVAAYPLENGDSVIIGLPLSDVQATVGRLTFVIVLVTLAGIVSAFFLASFVI 207 Query 207 GYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDG 266 A+RPL RVA TA +VA MPL D +SVRV DTD EVG VG LNR+L +V Sbjct 208 RLAMRPLERVAGTAEQVAHMPLDRGDVALSVRVPEEDTDAHTEVGKVGAALNRMLGHVAS 267 Query 267 ALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEAR 326 AL R S+L++RQF+ DASHELRTPLA+I+GYAELTR+ +LP ++L RIESEA Sbjct 268 ALTARQASELKVRQFVADASHELRTPLASIRGYAELTRRSPHELPRDVTHSLGRIESEAT 327 Query 327 RMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVN 386 RMT LV++LLLL+RL EG +L+ + +DL+ L+++A++DA A P H W LP+EPV V Sbjct 328 RMTSLVEDLLLLARLDEGRELDRDPVDLSLLLVDALSDAHAAGPGHAWSILLPEEPVDVL 387 Query 387 GDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILP 446 GD RLHQ+V+NLL NA +HT VT +T A ++V DDGP I + Sbjct 388 GDAQRLHQVVANLLANARLHTPEATKVTASLTVDAEAGQA---VVTVADDGPGIPEGLQS 444 Query 447 HLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 LF+RF R SR+ +G GLGLAIV ++V AH G+V+ +S G TVF VRLP+ Sbjct 445 TLFERFARGDSSRARTTGSTGLGLAIVQAVVVAHDGTVSVQSRPGDTVFTVRLPL 499 >gi|340628735|ref|YP_004747187.1| putative two component sensor kinase [Mycobacterium canettii CIPT 140010059] gi|340006925|emb|CCC46115.1| putative two component sensor kinase [Mycobacterium canettii CIPT 140010059] Length=475 Score = 294 bits (752), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 181/416 (44%), Positives = 253/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTARSQLERIAGSRTPLTLDLDGL 119 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 174 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 175 IKRALAPLRRVAQTASEVVDLPLDRGEVELPVRVPEPDANPSTEVGQLGSALNRMLDHIA 234 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 235 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 293 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE E +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 294 ERITRLVEDLLLLARLDSGRPLEREPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 353 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 354 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 408 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 409 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGHTEFAVRLPL 464 >gi|159037875|ref|YP_001537128.1| histidine kinase [Salinispora arenicola CNS-205] gi|157916710|gb|ABV98137.1| histidine kinase [Salinispora arenicola CNS-205] Length=477 Score = 293 bits (751), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 187/409 (46%), Positives = 253/409 (62%), Gaps = 14/409 (3%) Query 97 GQTPGNLIAVLHDGVVIGSAVFS---EDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLG 153 G G+++A+L DG V + + + E G R AP + + A+ V + GP R LG LG Sbjct 71 GMEVGSVVALLRDGRVAKARIQTAAREGGERIAP-ERVAALGPLVPNAGP-RTVDLGDLG 128 Query 154 AYQ-VDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRP 212 Y+ + + + L+ + + R V + G LVV +V LRP Sbjct 129 EYRAIARQWRDGEVTAFALPLAEVQETVMRMVVAQAGVAGTGLVVAGTTGALMVRRTLRP 188 Query 213 LRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRV 272 LRRVAATA V+ +PL + + VRV DTDP EVG VG LNR+L +V ALA R Sbjct 189 LRRVAATARRVSELPLDRGEVTLPVRVPEADTDPRTEVGQVGAALNRMLGHVAAALAARQ 248 Query 273 DSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLV 332 S+ R+RQF+ DASHELRTPLAAI+GYAE+ R+ +PP +AL R+ESE+ RMT LV Sbjct 249 ASETRVRQFVADASHELRTPLAAIRGYAEVARRGRDRVPPDVAHALRRVESESTRMTGLV 308 Query 333 DELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARL 392 ++LLLL+RL G L + +DL+ LV++AV+DA VA P HRW +LP++ + V GD ARL Sbjct 309 EDLLLLARLDSGRPLAVQPVDLSALVVDAVSDAHVAGPEHRWQLDLPEQQIGVPGDPARL 368 Query 393 HQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRF 452 HQ+V+NLL NA VHT G TVT + P+A L V DDGP I ++ P +F+RF Sbjct 369 HQVVANLLANARVHTPAGTTVTTSLAVE---PDAAV--LRVADDGPGIPEDLQPEVFERF 423 Query 453 VR--ASKSRSNGSGHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 R +S+SRS+GS GLGLAIV+++V AH G V+ +S G+TVF VRLP Sbjct 424 ARGDSSRSRSHGS-TGLGLAIVAAVVDAHHGVVSVQSRPGRTVFTVRLP 471 >gi|342860016|ref|ZP_08716668.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035] gi|342132394|gb|EGT85623.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035] Length=509 Score = 293 bits (749), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 197/504 (40%), Positives = 282/504 (56%), Gaps = 28/504 (5%) Query 9 SRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNH 68 SR A R SLR +LL+G + V+ +V V + + L+L ++ A D +L Sbjct 4 SRPADTRRVWSLRLRLLVGQIVVLAIVCVGITAATELALLHHLVAQLDGQL--------- 54 Query 69 SYTRYRDSAQTSTPTGNLPMSQAV----------LEFTGQTPGNLIAVLHDGVVIGSAVF 118 + T YR + P + Q V L+ GQ G + AV+ G + + Sbjct 55 AGTSYRSALMYPEPPHSGWRHQHVYPRPGPGPRFLDAPGQPAGMVAAVVSHGNTVDAGYT 114 Query 119 SEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAA--GADRLFVGVSLSLA 176 + G R + + + P L LG Y+V ++ + G D + G+S++ Sbjct 115 TSSGDRAELTPTAQRQLSGIAGSRKPVTLDLDGLGRYRVVAAPSRNGGDVIVTGLSMANI 174 Query 177 NQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQIS 236 + + R V + ALV V ++ AL PLRRVA TA+EVA +PL + ++ Sbjct 175 DTTLMRMLVIFGIVTVIALVAATTAGVIIIRRALAPLRRVAQTASEVAGLPLARGEVELP 234 Query 237 VRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAI 296 VRVR D +P EVG +G LN++LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI Sbjct 235 VRVREADANPSTEVGQLGAALNQMLDHIAAALSARQASETRVRQFVADASHELRTPLAAI 294 Query 297 QGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTD 356 +GY ELT++ D + A++R+ SE RMT LV++LLLL+RL G LE E +DL+ Sbjct 295 RGYTELTQRMGDDREAVAQ-AMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSR 353 Query 357 LVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIG 416 L ++AV+DA VA P H+W +LP+EPV V GD ARLHQ+++NLL NA VHT G VT Sbjct 354 LAVDAVSDAHVAGPDHQWELDLPEEPVVVTGDAARLHQVLANLLANARVHTGAGTVVTTR 413 Query 417 ITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSI 475 ++ T P+ L V D+GP I + +F+RF R SRS G GLGLAIVS++ Sbjct 414 LS---TEPSHTV--LQVIDNGPGIPAALQSEVFERFARGDSSRSRKGGSTGLGLAIVSAV 468 Query 476 VKAHRGSVTAESGNGQTVFRVRLP 499 VKAH G++ +S G+T F VRLP Sbjct 469 VKAHNGTIAVDSAPGRTEFTVRLP 492 >gi|312200459|ref|YP_004020520.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EuI1c] gi|311231795|gb|ADP84650.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EuI1c] Length=616 Score = 291 bits (744), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 193/444 (44%), Positives = 259/444 (59%), Gaps = 33/444 (7%) Query 82 PTGNLPMSQAVLEFT---GQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIR---AIE 135 P+G P +F GQ+ G + A + G V E PAP +V + A E Sbjct 89 PSGVQPWQGTPTDFVNLQGQSTGTVAAHIVGGKV-------ETAVIPAPGEVAKQLPASE 141 Query 136 AQVWDGGP----PRVESLGSLGAYQVDSS-AAGADRLFVGVSLSLANQIIARKKVTTVAL 190 A P PR +LGS G Y+V + + G+SLS N + + + + Sbjct 142 AAKLAAIPVDDTPRTVTLGSFGEYRVTARLVPDGTAVVSGLSLSEVNATVDQLIIIAGCV 201 Query 191 VGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEV 250 G +++ + V LRPLRRVAATAA+VA +PL + VRV DTDP EV Sbjct 202 AGCGVLLLGVVGAVTVRRTLRPLRRVAATAAQVAELPLDRGAVTLRVRVPDVDTDPRTEV 261 Query 251 GIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTR----QD 306 G VG LN +L +V ALA R S+ R+RQF+ DASHELRTPLAAI GYA+LTR Q+ Sbjct 262 GQVGAALNHMLGHVGAALAARHASETRVRQFVADASHELRTPLAAISGYAQLTRRIGAQN 321 Query 307 SSD------LPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVIN 360 D +PP YAL+R+ESE +RMT LV++LLLL+RL G LE D+DL+ LV++ Sbjct 322 GFDDPLRPLVPPDVAYALSRVESETKRMTTLVEDLLLLARLDSGRPLEHGDVDLSLLVVD 381 Query 361 AVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITC- 419 V+DA +AAP HR+ +LP +PV V GD ARLHQ+++NLL NA HT G +VT+ + Sbjct 382 VVSDAHIAAPGHRFSLSLPADPVTVRGDQARLHQVLANLLANARTHTPAGTSVTVALELP 441 Query 420 --HRTGPNAPC-VELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSI 475 TG + V LSV DDGP I ++LP++F+RF R SRS +G GLGLAIV+++ Sbjct 442 PGSGTGDSLTGEVRLSVIDDGPGIPADLLPNVFERFARGDSSRSRAAGSTGLGLAIVAAV 501 Query 476 VKAHRGSVTAESGNGQTVFRVRLP 499 V+AH G ++ S G+T F V LP Sbjct 502 VEAHGGRISVTSSPGRTAFTVTLP 525 >gi|31794934|ref|NP_857427.1| putative two component sensor kinase [Mycobacterium bovis AF2122/97] gi|121639678|ref|YP_979902.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224992174|ref|YP_002646863.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Tokyo 172] 16 more sequence titles Length=475 Score = 290 bits (742), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 180/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 119 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 174 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 175 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 234 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 235 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 293 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 294 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 353 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 354 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 408 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 409 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 >gi|254366309|ref|ZP_04982353.1| hypothetical two component sensor kinase [Mycobacterium tuberculosis str. Haarlem] gi|298527237|ref|ZP_07014646.1| sensor histidine kinase [Mycobacterium tuberculosis 94_M4241A] gi|134151821|gb|EBA43866.1| hypothetical two component sensor kinase [Mycobacterium tuberculosis str. Haarlem] gi|298497031|gb|EFI32325.1| sensor histidine kinase [Mycobacterium tuberculosis 94_M4241A] gi|323717629|gb|EGB26831.1| two component system sensor kinase [Mycobacterium tuberculosis CDC1551A] gi|339296571|gb|AEJ48682.1| two component sensor kinase [Mycobacterium tuberculosis CCDC5079] gi|339300170|gb|AEJ52280.1| two component sensor kinase [Mycobacterium tuberculosis CCDC5180] Length=478 Score = 290 bits (742), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 180/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 63 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 122 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 123 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 177 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 178 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 237 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 238 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 296 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 297 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 356 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 357 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 411 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 412 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 467 >gi|289556029|ref|ZP_06445239.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 605] gi|289440661|gb|EFD23154.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 605] Length=490 Score = 290 bits (742), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 180/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 75 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 134 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 135 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 189 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 190 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 249 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 250 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 308 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 309 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 368 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 369 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 423 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 424 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 479 >gi|254552878|ref|ZP_05143325.1| two component system sensor kinase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|289759926|ref|ZP_06519304.1| two component sensor kinase [Mycobacterium tuberculosis T85] gi|289763946|ref|ZP_06523324.1| two component sensor kinase [Mycobacterium tuberculosis GM 1503] 7 more sequence titles Length=475 Score = 290 bits (742), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 180/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 119 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 174 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 175 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 234 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 235 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 293 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 294 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 353 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 354 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 408 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 409 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 >gi|15843384|ref|NP_338421.1| sensor histidine kinase [Mycobacterium tuberculosis CDC1551] gi|148824969|ref|YP_001289723.1| two component sensor kinase [Mycobacterium tuberculosis F11] gi|253800811|ref|YP_003033812.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 1435] 25 more sequence titles Length=506 Score = 290 bits (741), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 180/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 91 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 150 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +ALV A TA + + Sbjct 151 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA---TTAGIVI-- 205 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 206 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 265 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 266 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 324 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 325 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 384 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 385 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 439 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 440 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 495 >gi|170780990|ref|YP_001709322.1| putative two component sensor kinase [Clavibacter michiganensis subsp. sepedonicus] gi|169155558|emb|CAQ00674.1| putative two component sensor kinase [Clavibacter michiganensis subsp. sepedonicus] Length=527 Score = 290 bits (741), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 194/497 (40%), Positives = 283/497 (57%), Gaps = 20/497 (4%) Query 19 SLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYTRYRDSAQ 78 +LR++L+L V+ ++ + + +G VS+L+L + D +L E+ A + + Sbjct 2 TLRRRLVLSVVGLLALASIFIGTVSILALRTSLMQQVDQQL-EATAARSQDFVDREPGGY 60 Query 79 TSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDV-------- 130 G+ P + L GQ G + A + DGVV G + A+ P Sbjct 61 -----GSFPGAPGGLGAFGQQVGTISATIIDGVVSGGYIADRSAAQGEPGGAGAVELTQR 115 Query 131 -IRAIEAQVWDGGPPRVESLGSLGAYQV--DSSAAGADRLFVGVSLSLANQIIARKKVTT 187 +++ DG P V+ G+LG+Y++ +S++GA + G+ A+ ++ + + Sbjct 116 QSEQLQSVPTDGVPRTVDLGGALGSYRLVGQTSSSGAT-IVTGLPTKPADDVVEQLILVI 174 Query 188 VALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPD 247 + L + A L +V ALRPL RV TA VA + L D + RV DTD Sbjct 175 TVVAAITLALAALLGTLIVRRALRPLDRVVDTATHVAALELDRGDVALEARVPASDTDER 234 Query 248 NEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDS 307 EVG VG LN LL +V AL+ R S+ ++R+F++DASHELRTPLA+I+GYAELTR+ Sbjct 235 TEVGRVGAALNGLLGHVAAALSSRQASEAKVRRFVSDASHELRTPLASIRGYAELTRRGP 294 Query 308 SDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAV 367 LP ++L+RIESE+ RMT +V++LLLL+RL EG +LE++ +DLT ++++ V DA+ Sbjct 295 HQLPEDVTHSLSRIESESVRMTTIVEDLLLLARLDEGRELESDPIDLTRILLDTVGDASA 354 Query 368 AAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAP 427 A P H W +LPD V V GD ARL Q+V NLL NA HT G V + GP+A Sbjct 355 AGPDHDWDLDLPDGSVTVPGDDARLRQVVVNLLANARTHTPAGTRVVTSLAVEGAGPDAH 414 Query 428 CVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAE 486 V + VTDDGP I P + LF+RFVR SR+ +G GLGLAI +IV AH G+V E Sbjct 415 TV-IRVTDDGPGIPPALQETLFERFVRGDGSRARTTGGTGLGLAIAQAIVSAHHGAVWVE 473 Query 487 SGNGQTVFRVRLPMIEQ 503 S G+TVF VRLP++ + Sbjct 474 SEPGRTVFGVRLPVVRR 490 >gi|289445363|ref|ZP_06435107.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] gi|289418321|gb|EFD15522.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] Length=475 Score = 289 bits (739), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 179/416 (44%), Positives = 252/416 (61%), Gaps = 19/416 (4%) Query 93 LEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSL 152 L+ GQ G + AV+ DG + + + G+R A R+ ++ P L L Sbjct 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 119 Query 153 GAYQVDSSAA--GADRLFVGVSL-----SLANQIIARKKVTTVALVGAALVVTAALTVWV 205 G Y+V ++ + G D + G+S+ ++ +I VT +A+V A TA + + Sbjct 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIAVVAA---TTAGIVI-- 174 Query 206 VGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVD 265 + AL PLRRVA TA+EV +PL + ++ VRV D +P EVG +G LNR+LD++ Sbjct 175 IKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIA 234 Query 266 GALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEA 325 AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT++ D P +A++R+ SE Sbjct 235 AALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASET 293 Query 326 RRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWV 385 R+T LV++LLLL+RL G LE +D++ L ++AV+DA VA P H+W +LP EPV + Sbjct 294 ERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVI 353 Query 386 NGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEIL 445 GD ARLHQ+V+NLL NA VHT PG VT ++ TGP V L V D+GP I + Sbjct 354 PGDAARLHQVVTNLLANARVHTGPGTIVTTRLS---TGPT--HVVLQVIDNGPGIPAALQ 408 Query 446 PHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 +F+RF R SRS +G GLGLAIVS++VKAH G++T S G T F VRLP+ Sbjct 409 SEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 >gi|88856022|ref|ZP_01130684.1| two-component system, sensor protein [marine actinobacterium PHSC20C1] gi|88814889|gb|EAR24749.1| two-component system, sensor protein [marine actinobacterium PHSC20C1] Length=496 Score = 289 bits (739), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 202/502 (41%), Positives = 279/502 (56%), Gaps = 25/502 (4%) Query 8 RSRKAP-CWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV----ES 62 R +AP R SLR +L++G A++ + V +GVVSVL+L G++T DA+L S Sbjct 5 REVRAPGTGRRHSLRTRLVIGSAALIALAAVLIGVVSVLALQGFLTERLDAQLTAASSRS 64 Query 63 LHALN-HSYTRYRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSED 121 AL+ HS R Q PTG+ L GQ G + ++ I + V Sbjct 65 QGALDGHS----RGFGQQPPPTGDF------LALPGQREGTIAGLVSSTGTITAGVLGNR 114 Query 122 GAR-PAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQV--DSSAAGADRLFVGVSLSLANQ 178 GA P I + P V+ GSLG Y+V S+ + L V + L+ Sbjct 115 GASAPLTEQQIAVLATLDKLDSPVTVDLGGSLGEYRVIVSSTPVAGESLIVALPLADVRD 174 Query 179 IIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVR 238 + + + V + A+ + A V ALRPL RVAATA V + L ++ R Sbjct 175 TVLQLTLLVVGIGLLAVTIAALAGAVAVRIALRPLERVAATATRVTELQLDRGAVALAER 234 Query 239 VRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQG 298 V D DP EVG VG LNR+L++V AL+ R S+ ++R F+ DASHELRTPLA+I+G Sbjct 235 VSLDDADPRTEVGQVGAALNRMLEHVASALSARQTSENKVRAFVADASHELRTPLASIRG 294 Query 299 YAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLV 358 YAE+TR+ D+P +A+ RIE+E+ RMT LV+ LLLL+RL E +E E +DLT L+ Sbjct 295 YAEVTRRGGHDIPADVAHAVGRIEAESVRMTALVESLLLLARLDETAQVELESVDLTRLI 354 Query 359 INAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGIT 418 I+AV DA A+P H W L D + V+GD AR+HQ+++NLL NA +HT G VT T Sbjct 355 IDAVGDAHAASPDHVWELELADHAIAVSGDRARIHQVIANLLANARLHTPVGTVVT---T 411 Query 419 CHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-GLGLAIVSSIVK 477 C ++ +E + D GP I + P +F+RFVR SRS SG GLGLAIV+++V Sbjct 412 CLMREGDSAIIE--IRDTGPGIPAALQPTVFERFVRGDSSRSRASGSTGLGLAIVAAVVG 469 Query 478 AHRGSVTAESGNGQTVFRVRLP 499 AH G+ + S G TVFRV LP Sbjct 470 AHGGTASVSSEPGNTVFRVELP 491 >gi|333992681|ref|YP_004525295.1| two-component sensor kinase TcrY [Mycobacterium sp. JDM601] gi|333488649|gb|AEF38041.1| two-component sensor kinase TcrY [Mycobacterium sp. JDM601] Length=506 Score = 288 bits (738), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 203/517 (40%), Positives = 284/517 (55%), Gaps = 28/517 (5%) Query 1 MIPDRNTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELV 60 M R + S +A R SLR +LL G +A++TV + +G V+ L+L Y+ + D +L Sbjct 1 MSSSRPSESLRAGTRRSWSLRARLLAGQVALLTVACLGIGAVTELALYQYLVSQLDHQLS 60 Query 61 ESLHALNHSYTRYRDSAQTSTPTGNLPMSQAVLEFT---GQTPGNLIAVLH--DGV--VI 113 ++ A + + A + P +F GQ G + AV+ DG + Sbjct 61 DA--ARRSARLHGQPPAPPGHRPRHRPRPGPGPDFLDAPGQPVGMVGAVVDSVDGEDRIA 118 Query 114 GSAVFSEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAA--GADRLFVGV 171 + S G R A + P L +G Y++ ++ A G + + +G+ Sbjct 119 DAGCLSTSGLREELSASATTQLAGIVAEPAPVTRRLDGVGRYRLVATNARHGGETIIIGL 178 Query 172 SLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDD 231 L+ N + R + + A+ A V AL PLRRVA TA EVA +PL Sbjct 179 PLAAVNATMVRVLLIFGLVTLVAVAAAATAGSVVTRRALAPLRRVAQTAGEVADLPLDRG 238 Query 232 DHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRT 291 + + VRV DT+P EVG +G +NR+LD++ ALA+R S+ R+RQF+ DASHELRT Sbjct 239 EATLPVRVAESDTNPRTEVGQLGAAVNRMLDHIAAALANRQASETRVRQFVADASHELRT 298 Query 292 PLAAIQGYAELTRQ-------DSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEG 344 PL AI+GY EL ++ DS L +AL+R++SE +RMT LV++LLLL+RL G Sbjct 299 PLTAIRGYTELAQRIPVADGVDSESL----AHALSRVQSETQRMTQLVEDLLLLARLDSG 354 Query 345 EDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAW 404 LE E +DL+ L ++AV+DA V P H+W +LPDEPV V GD ARLHQ+++NLLTNA Sbjct 355 RPLEHEPVDLSRLAVDAVSDAHVGGPDHQWELDLPDEPVTVPGDAARLHQVLTNLLTNAR 414 Query 405 VHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGS 463 VHT G VT R G + L VTDDGP I E P +F+RF R SRS G Sbjct 415 VHTGAGTVVTT-----RLGVDGAEAVLCVTDDGPGIPAEFQPEIFERFARGDTSRSRKGG 469 Query 464 GHGLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLPM 500 GLGLAI S++V+AHRG++ S G T F VRLP+ Sbjct 470 STGLGLAIASAVVRAHRGTIAVTSRPGHTEFTVRLPL 506 >gi|296166888|ref|ZP_06849305.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897765|gb|EFG77354.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=500 Score = 288 bits (738), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 192/497 (39%), Positives = 276/497 (56%), Gaps = 17/497 (3%) Query 12 APCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHALNHSYT 71 A R SLR +LL+G + V+ +V V + V+ L+L+ ++ D +L + Y Sbjct 2 ADARRAWSLRLRLLVGQIVVLAIVCVGITAVTELALNHHLVKQLDGQLAGTSFRSALMYP 61 Query 72 R-----YRDSAQTSTPTGNLPMSQAVLEFTGQTPGNLIAVLHDGVVIGSAVFSEDGARPA 126 +R G P L+ GQ G + AV++ G I + + G R A Sbjct 62 EPKRPGWRHEHSYFPRPGPGPR---FLDAPGQPAGMVAAVVNHGKAIDAGYLTGSGTRAA 118 Query 127 PPDVIRAIEAQVWDGGPPRVESLGSLGAYQVDSSAA--GADRLFVGVSLSLANQIIARKK 184 +A ++ P L LG Y+V ++ + G D + G+S+S + + R Sbjct 119 LTPAAQAQLERIAASHAPVTLDLDGLGRYRVMAAPSRNGGDIIVTGLSMSNIDATLIRML 178 Query 185 VTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPLTDDDHQISVRVRPGDT 244 + + AL V +V AL PLRRVA TA+ VA +PL + ++ +RVR D Sbjct 179 IIFGIVTAIALAAATIAGVIIVRRALAPLRRVAQTASRVADLPLDRGEVELPLRVRESDA 238 Query 245 DPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHELRTPLAAIQGYAELTR 304 +P EVG +G LNR+LD++ AL+ R S+ R+RQF+ DASHELRTPLAAI+GY ELT+ Sbjct 239 NPATEVGQLGSALNRMLDHIAAALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQ 298 Query 305 QDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLETEDLDLTDLVINAVND 364 + D +A++R+ SE RMT LV++LLLL+RL G LE E +DL+ + ++AVND Sbjct 299 RMGDDR-EAVAHAMSRVASETERMTRLVEDLLLLARLDSGRPLEREPVDLSRVALDAVND 357 Query 365 AAVAAPTHRWVKNLPDEPVWVNGDHARLHQLVSNLLTNAWVHTQPGVTVTIGITCHRTGP 424 A VA P H+W +LP+EPV V GD ARLHQ+++NLL NA +HT G VT ++ T Sbjct 358 AHVAGPDHQWELDLPEEPVIVTGDAARLHQVLANLLANARLHTGAGTVVTTRLSAEPT-- 415 Query 425 NAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRS-NGSGHGLGLAIVSSIVKAHRGSV 483 L V D+GP I + +F+RF R SRS G GLGLAIVS++V+AH G++ Sbjct 416 ---HTVLQVIDNGPGIPAVLQSEVFERFARGDTSRSRKGGSTGLGLAIVSAVVRAHNGTI 472 Query 484 TAESGNGQTVFRVRLPM 500 S G T F VRLP+ Sbjct 473 AVNSSPGHTEFTVRLPL 489 >gi|258654799|ref|YP_003203955.1| histidine kinase [Nakamurella multipartita DSM 44233] gi|258558024|gb|ACV80966.1| histidine kinase [Nakamurella multipartita DSM 44233] Length=473 Score = 288 bits (738), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 183/407 (45%), Positives = 250/407 (62%), Gaps = 6/407 (1%) Query 97 GQTPGNLIAVLHDGVVIGSAVF---SEDGARPAPPDVIRAIEAQVWDGGPPRVESLGSLG 153 GQ+ +L V+ DG V+ + S G P D + + P V G Sbjct 65 GQSAYSLTGVIVDGQVVNAWTVTPKSSTGCTPLSADADAVLLSIAPAAAPQTVTIPGLDS 124 Query 154 AYQVDSSAAGADRLFVGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPL 213 +Y+V++S + G+S + + + + + + G AL+ VW+V +LRPL Sbjct 125 SYRVEASTRNGVTVVSGLSTAQVQGSLFQLAMILLIVTGVALIAGGFAVVWIVRRSLRPL 184 Query 214 RRVAATAAEVATMPLTDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVD 273 RVAATA +V T+PL + + VRV DTD EVG VG LN++L +V GAL R + Sbjct 185 DRVAATARQVTTLPLDRGEVDLGVRVPEQDTDTRTEVGQVGAALNQMLGHVSGALKSRQE 244 Query 274 SDLRMRQFITDASHELRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVD 333 S+ R+RQF+ DASHELRTPLA+I+GYAEL R+D D T +AL R+ESE+ RM+ LVD Sbjct 245 SETRVRQFVADASHELRTPLASIRGYAELARRDEHD-AQTVGHALRRVESESARMSTLVD 303 Query 334 ELLLLSRLSEGEDLETEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPVWVNGDHARLH 393 +LLLL+RL G L + +D++ L+I+AV+DA VA THRW +LP+EPV V GD ARLH Sbjct 304 DLLLLARLDSGRPLSADQVDMSMLIIDAVSDARVAGATHRWQLDLPEEPVTVIGDGARLH 363 Query 394 QLVSNLLTNAWVHTQPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFV 453 Q+++NLL NA HT G TV G+ GP ++VTDDGP I + P +F+RFV Sbjct 364 QVLTNLLANARTHTPAGSTVRCGLRTE-AGPGGTWAVITVTDDGPGIPAALQPEIFNRFV 422 Query 454 RASKSRSNGSGH-GLGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 R SRS G+G GLGLAIV+++V AHRG+VT +S G+TVF VRLP Sbjct 423 RGDSSRSRGAGSTGLGLAIVAAVVGAHRGTVTVQSRPGRTVFTVRLP 469 >gi|328883820|emb|CCA57059.1| Two-component system, sensor protein [Streptomyces venezuelae ATCC 10712] Length=519 Score = 287 bits (735), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 207/513 (41%), Positives = 279/513 (55%), Gaps = 37/513 (7%) Query 6 NTRSRKAPCWRPRSLRQQLLLGVLAVVTVVLVAVGVVSVLSLSGYVTAMNDAELVESLHA 65 RSR + RP SLR +L++ +A++ VV +G V+ ++ Y+ D E + A Sbjct 6 GQRSRPSRAGRPWSLRTRLVVSAVALIAVVAAVIGTVTTIAFRSYLYDRAD----EEVRA 61 Query 66 LNHSYTRYRDSAQTSTPTGNLPMSQAV----LEFT---GQTPGNLIAVLHDGVVI--GSA 116 ++H + P LP L F G G L AVL G V G + Sbjct 62 VSH---------WAAGPPAALPEPGRAGTDQLRFVVGPGAKTGTLGAVLTGGEVTAAGYS 112 Query 117 VFSEDGARPAPPDVIR--------AIEAQVWDGGPPRVESLGSLGAYQVDSSAAGADRLF 168 +ED PP+ I+ A+ A DG P V+ G LG+Y+V + G Sbjct 113 AEAEDSGVYGPPERIKPLDDAQRAALAAVPRDGRPHTVDLPGGLGSYRVAYAEGGKGTFL 172 Query 169 VGVSLSLANQIIARKKVTTVALVGAALVVTAALTVWVVGYALRPLRRVAATAAEVATMPL 228 G+ L+ ++ + +++ GA L + +V ALRPLRRVA TA +VA +PL Sbjct 173 TGIPLAEVEDALSTLILVELSVTGAGLFAASLAGTVLVRVALRPLRRVAVTARQVAQLPL 232 Query 229 TDDDHQISVRVRPGDTDPDNEVGIVGHTLNRLLDNVDGALAHRVDSDLRMRQFITDASHE 288 + + RV + DP EVG VG +NR+LD+V AL R S+ R+RQF+ DASHE Sbjct 233 HSGEVALHQRVPEPEADPRTEVGQVGAAINRMLDHVHSALDARQQSETRVRQFVADASHE 292 Query 289 LRTPLAAIQGYAELTRQDSSDLPPTTEYALARIESEARRMTLLVDELLLLSRLSEGEDLE 348 LRTPLA+I+GYAELTR+ + P T +AL RIESEA RMT LV++LLLL+RL G L Sbjct 293 LRTPLASIRGYAELTRRGGEECGPDTRHALGRIESEATRMTGLVEDLLLLARLDAGRPLS 352 Query 349 TEDLDLTDLVINAVNDAAVAAPTHRWVKNLPDEPV-WVNGDHARLHQLVSNLLTNAWVHT 407 E DL LV++AV+DA A P H W LP++ V D AR+ Q++ NLL NA HT Sbjct 353 YEPTDLLPLVVDAVSDARAAGPGHHWSLELPEDGAPPVRADGARIQQVLVNLLANARTHT 412 Query 408 QPGVTVTIGITCHRTGPNAPCVELSVTDDGPDIDPEILPHLFDRFVRASKSRSNGSGH-G 466 PG VT + G V + + DDGP I PE+LP +F+RF R SRS +G G Sbjct 413 PPGTKVTARVRTDGAG-----VIVQIEDDGPGIPPELLPAVFERFARGDASRSRNAGSTG 467 Query 467 LGLAIVSSIVKAHRGSVTAESGNGQTVFRVRLP 499 LGLAIV ++V AH G V ES G+TVF VRLP Sbjct 468 LGLAIVRAVVGAHGGDVDVESAPGRTVFTVRLP 500 Lambda K H 0.317 0.133 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1104784772540 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40