BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1033c Length=257 Score E Sequences producing significant alignments: (Bits) Value gi|15840463|ref|NP_335500.1| DNA-binding response regulator TrcR... 513 1e-143 gi|289555184|ref|ZP_06444394.1| two component system transcripti... 512 2e-143 gi|15608173|ref|NP_215549.1| two component transcriptional regul... 512 2e-143 gi|339631095|ref|YP_004722737.1| transcriptional regulator [Myco... 509 1e-142 gi|308375329|ref|ZP_07443555.2| two component system transcripti... 506 1e-141 gi|118619706|ref|YP_908038.1| two component transcriptional regu... 472 2e-131 gi|183984426|ref|YP_001852717.1| two-component transcriptional r... 470 9e-131 gi|240169874|ref|ZP_04748533.1| two component transcriptional re... 464 8e-129 gi|296169906|ref|ZP_06851518.1| DNA-binding response regulator [... 455 3e-126 gi|342861637|ref|ZP_08718283.1| hypothetical protein MCOL_22226 ... 448 4e-124 gi|41407100|ref|NP_959936.1| hypothetical protein MAP1002c [Myco... 444 8e-123 gi|118466262|ref|YP_880424.1| TrcR family transcriptional regula... 439 1e-121 gi|254820268|ref|ZP_05225269.1| hypothetical protein MintA_10086... 437 7e-121 gi|333992567|ref|YP_004525181.1| two-component transcriptional r... 402 3e-110 gi|120403287|ref|YP_953116.1| two component transcriptional regu... 382 3e-104 gi|118471523|ref|YP_887235.1| DNA-binding response regulator, Ph... 365 3e-99 gi|119717917|ref|YP_924882.1| response regulator receiver [Nocar... 308 5e-82 gi|269796544|ref|YP_003315999.1| CheY-like receiver domain/winge... 306 1e-81 gi|148273950|ref|YP_001223511.1| putative two-component system, ... 305 4e-81 gi|170780989|ref|YP_001709321.1| putative two component response... 305 4e-81 gi|336116252|ref|YP_004571018.1| two-component system response r... 300 1e-79 gi|84495357|ref|ZP_00994476.1| putative two component system res... 300 2e-79 gi|88856021|ref|ZP_01130683.1| two-component system, regulatory ... 299 3e-79 gi|326333582|ref|ZP_08199821.1| DNA-binding response regulator T... 299 3e-79 gi|330468634|ref|YP_004406377.1| two component transcriptional r... 299 3e-79 gi|324999382|ref|ZP_08120494.1| two component transcriptional re... 298 4e-79 gi|331698780|ref|YP_004335019.1| winged helix family two compone... 297 8e-79 gi|315094756|gb|EFT66732.1| response regulator receiver domain p... 297 1e-78 gi|159037874|ref|YP_001537127.1| two component transcriptional r... 296 2e-78 gi|329946290|ref|ZP_08293884.1| response regulator MprA [Actinom... 294 8e-78 gi|145594662|ref|YP_001158959.1| response regulator receiver [Sa... 294 8e-78 gi|111220170|ref|YP_710964.1| putative two-component system resp... 294 9e-78 gi|326772529|ref|ZP_08231813.1| DNA-binding response regulator T... 293 1e-77 gi|29830741|ref|NP_825375.1| two-component system response regul... 293 2e-77 gi|289770395|ref|ZP_06529773.1| two component system response re... 292 3e-77 gi|317126455|ref|YP_004100567.1| transcriptional regulator [Intr... 292 3e-77 gi|302559780|ref|ZP_07312122.1| DNA-binding response regulator T... 292 3e-77 gi|21222423|ref|NP_628202.1| two component system response regul... 292 3e-77 gi|302552564|ref|ZP_07304906.1| phosphate regulon transcriptiona... 292 3e-77 gi|302544103|ref|ZP_07296445.1| DNA-binding response regulator T... 292 3e-77 gi|302867311|ref|YP_003835948.1| response regulator receiver [Mi... 292 4e-77 gi|294630229|ref|ZP_06708789.1| DNA-binding response regulator T... 291 5e-77 gi|50843487|ref|YP_056714.1| putative two-component system respo... 291 6e-77 gi|152966980|ref|YP_001362764.1| winged helix family two compone... 291 7e-77 gi|323359410|ref|YP_004225806.1| response regulator consisting o... 291 8e-77 gi|297200795|ref|ZP_06918192.1| phosphate regulon transcriptiona... 291 8e-77 gi|325066524|ref|ZP_08125197.1| two component system response re... 291 9e-77 gi|343522475|ref|ZP_08759441.1| response regulator receiver doma... 290 1e-76 gi|297625540|ref|YP_003687303.1| two component system response r... 290 1e-76 gi|289428055|ref|ZP_06429759.1| response regulator receiver doma... 290 1e-76 >gi|15840463|ref|NP_335500.1| DNA-binding response regulator TrcR [Mycobacterium tuberculosis CDC1551] gi|254231325|ref|ZP_04924652.1| two component transcriptional regulator trcR [Mycobacterium tuberculosis C] gi|13880635|gb|AAK45314.1| DNA-binding response regulator TrcR [Mycobacterium tuberculosis CDC1551] gi|124600384|gb|EAY59394.1| two component transcriptional regulator trcR [Mycobacterium tuberculosis C] Length=276 Score = 513 bits (1321), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 257/257 (100%), Positives = 257/257 (100%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV Sbjct 20 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 79 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT Sbjct 80 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 139 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT Sbjct 140 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 199 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE Sbjct 200 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 259 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRGIGYMLRPPE Sbjct 260 PMIHTVRGIGYMLRPPE 276 >gi|289555184|ref|ZP_06444394.1| two component system transcriptional regulator trcR [Mycobacterium tuberculosis KZN 605] gi|289439816|gb|EFD22309.1| two component system transcriptional regulator trcR [Mycobacterium tuberculosis KZN 605] Length=263 Score = 512 bits (1318), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 257/257 (100%), Positives = 257/257 (100%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV Sbjct 7 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 66 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT Sbjct 67 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 126 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT Sbjct 127 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 186 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE Sbjct 187 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 246 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRGIGYMLRPPE Sbjct 247 PMIHTVRGIGYMLRPPE 263 >gi|15608173|ref|NP_215549.1| two component transcriptional regulator TRCR [Mycobacterium tuberculosis H37Rv] gi|31792225|ref|NP_854718.1| two component transcriptional regulator TRCR [Mycobacterium bovis AF2122/97] gi|121636963|ref|YP_977186.1| two component transcriptional regulator trcR [Mycobacterium bovis BCG str. Pasteur 1173P2] 71 more sequence titles Length=257 Score = 512 bits (1318), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 257/257 (100%), Positives = 257/257 (100%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV Sbjct 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT Sbjct 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT Sbjct 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE Sbjct 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRGIGYMLRPPE Sbjct 241 PMIHTVRGIGYMLRPPE 257 >gi|339631095|ref|YP_004722737.1| transcriptional regulator [Mycobacterium africanum GM041182] gi|339330451|emb|CCC26116.1| two component transcriptional regulator TRCR [Mycobacterium africanum GM041182] Length=257 Score = 509 bits (1312), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 256/257 (99%), Positives = 257/257 (100%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV Sbjct 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT Sbjct 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLTSGADDYMTKPFSLEELVARLRGLLRRSS+LERPADEALRVGDLTLDGASREVTRDGT Sbjct 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSYLERPADEALRVGDLTLDGASREVTRDGT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE Sbjct 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRGIGYMLRPPE Sbjct 241 PMIHTVRGIGYMLRPPE 257 >gi|308375329|ref|ZP_07443555.2| two component system transcriptional regulator trcR [Mycobacterium tuberculosis SUMu007] gi|308346707|gb|EFP35558.1| two component system transcriptional regulator trcR [Mycobacterium tuberculosis SUMu007] Length=254 Score = 506 bits (1304), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%), Gaps = 0/254 (0%) Query 4 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 63 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD Sbjct 1 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 60 Query 64 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 123 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT Sbjct 61 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 120 Query 124 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 183 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS Sbjct 121 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 180 Query 184 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 243 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI Sbjct 181 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 240 Query 244 HTVRGIGYMLRPPE 257 HTVRGIGYMLRPPE Sbjct 241 HTVRGIGYMLRPPE 254 >gi|118619706|ref|YP_908038.1| two component transcriptional regulator TrcR [Mycobacterium ulcerans Agy99] gi|118571816|gb|ABL06567.1| two component transcriptional regulator TrcR [Mycobacterium ulcerans Agy99] Length=257 Score = 472 bits (1215), Expect = 2e-131, Method: Compositional matrix adjust. Identities = 232/257 (91%), Positives = 246/257 (96%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 M M+G TR+QRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVE+ Sbjct 1 MKAMTGSTRTQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEI 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AH+G+EAI+KFDK+ PDVLVLDIMLPDVDGL+IL+RVR+SD YTPTLFLTARDSVMDRVT Sbjct 61 AHNGREAISKFDKISPDVLVLDIMLPDVDGLQILQRVRDSDAYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLT+GADDYMTKPFSLEELVARLRGLLRRSSHL PADE+L+VGDL LD ASREVTR GT Sbjct 121 GLTAGADDYMTKPFSLEELVARLRGLLRRSSHLAPPADESLKVGDLKLDAASREVTRGGT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKID+DRE Sbjct 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDADRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRGIGYMLRP E Sbjct 241 PMIHTVRGIGYMLRPAE 257 >gi|183984426|ref|YP_001852717.1| two-component transcriptional regulator TrcR [Mycobacterium marinum M] gi|183177752|gb|ACC42862.1| two-component transcriptional regulator TrcR [Mycobacterium marinum M] Length=254 Score = 470 bits (1210), Expect = 9e-131, Method: Compositional matrix adjust. Identities = 231/254 (91%), Positives = 245/254 (97%), Gaps = 0/254 (0%) Query 4 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 63 M+G TR+QRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVE+AH+ Sbjct 1 MTGSTRTQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEIAHN 60 Query 64 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 123 G+EAI+KFDK+ PDVLVLDIMLPDVDGL+IL+RVR+SD YTPTLFLTARDSVMDRVTGLT Sbjct 61 GREAISKFDKISPDVLVLDIMLPDVDGLQILQRVRDSDAYTPTLFLTARDSVMDRVTGLT 120 Query 124 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 183 +GADDYMTKPFSLEELVARLRGLLRRSSHL PADE+L+VGDL LD ASREVTR GTPIS Sbjct 121 AGADDYMTKPFSLEELVARLRGLLRRSSHLAPPADESLKVGDLKLDAASREVTRGGTPIS 180 Query 184 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 243 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKID+DREPMI Sbjct 181 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDADREPMI 240 Query 244 HTVRGIGYMLRPPE 257 HTVRGIGYMLRP E Sbjct 241 HTVRGIGYMLRPAE 254 >gi|240169874|ref|ZP_04748533.1| two component transcriptional regulator TrcR [Mycobacterium kansasii ATCC 12478] Length=254 Score = 464 bits (1193), Expect = 8e-129, Method: Compositional matrix adjust. Identities = 229/254 (91%), Positives = 244/254 (97%), Gaps = 0/254 (0%) Query 4 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 63 M+G R+QRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVE+AH+ Sbjct 1 MTGQPRTQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEIAHN 60 Query 64 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 123 G+EAIAKF+++ PDVLVLDIMLPDVDGL+IL+RVRESD YTPTLFLTARDSVMDRVTGLT Sbjct 61 GREAIAKFERISPDVLVLDIMLPDVDGLQILQRVRESDDYTPTLFLTARDSVMDRVTGLT 120 Query 124 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 183 +GADDYMTKPFSLEELVARLRGLLRRSSHL PADE+L+VGDL LD ASREVTR GTPIS Sbjct 121 AGADDYMTKPFSLEELVARLRGLLRRSSHLAPPADESLKVGDLKLDAASREVTRGGTPIS 180 Query 184 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 243 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKID+DR+PMI Sbjct 181 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDADRDPMI 240 Query 244 HTVRGIGYMLRPPE 257 HTVRGIGYMLRP E Sbjct 241 HTVRGIGYMLRPAE 254 >gi|296169906|ref|ZP_06851518.1| DNA-binding response regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895462|gb|EFG75164.1| DNA-binding response regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=257 Score = 455 bits (1171), Expect = 3e-126, Method: Compositional matrix adjust. Identities = 227/257 (89%), Positives = 238/257 (93%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MT MSGY QRPRQAILGQLPRI+RADGSPIRVLLVDDEPALTNLVKMALHYEGW V++ Sbjct 1 MTAMSGYAGGQRPRQAILGQLPRIYRADGSPIRVLLVDDEPALTNLVKMALHYEGWVVDI 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AH+G+EA+A FDKV PDVLVLDIMLPDVDGL IL RVR+SD YTPTLFLTARDSVMDRVT Sbjct 61 AHNGREAMATFDKVSPDVLVLDIMLPDVDGLRILERVRQSDAYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLT+GADDYMTKPFSLEELVARLRGLLRRS PADE L+VGDL LD ASREVTRDGT Sbjct 121 GLTAGADDYMTKPFSLEELVARLRGLLRRSGQQTPPADETLKVGDLRLDTASREVTRDGT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSR+EILDRVWNYDFAGRTSIVDLYISYLRKKIDS RE Sbjct 181 PISLSSTEFELLRFLMRNPRRALSRSEILDRVWNYDFAGRTSIVDLYISYLRKKIDSGRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG+GYMLRPPE Sbjct 241 PMIHTVRGVGYMLRPPE 257 >gi|342861637|ref|ZP_08718283.1| hypothetical protein MCOL_22226 [Mycobacterium colombiense CECT 3035] gi|342130771|gb|EGT84067.1| hypothetical protein MCOL_22226 [Mycobacterium colombiense CECT 3035] Length=257 Score = 448 bits (1152), Expect = 4e-124, Method: Compositional matrix adjust. Identities = 222/257 (87%), Positives = 236/257 (92%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MT MSGY+ +QRPRQAILGQLPRI+RADGSPIRVLLVDDEPALTNLVKMALHYEGW V++ Sbjct 1 MTAMSGYSGAQRPRQAILGQLPRIYRADGSPIRVLLVDDEPALTNLVKMALHYEGWVVDI 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AH+G+EA+AKFD+V PDVLVLDIMLPDVDGL IL RVR+SD YTPTLFLTARDSVMDRVT Sbjct 61 AHNGREAMAKFDRVSPDVLVLDIMLPDVDGLRILERVRQSDAYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLT+GADDYMTKPFSLEELVARLRGLLRRS P E L+VGDL +D ASREVTRDG Sbjct 121 GLTAGADDYMTKPFSLEELVARLRGLLRRSGQQPTPTAETLKVGDLKVDSASREVTRDGE 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDS RE Sbjct 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSGRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG+GYMLR E Sbjct 241 PMIHTVRGVGYMLRSAE 257 >gi|41407100|ref|NP_959936.1| hypothetical protein MAP1002c [Mycobacterium avium subsp. paratuberculosis K-10] gi|254774011|ref|ZP_05215527.1| hypothetical protein MaviaA2_04954 [Mycobacterium avium subsp. avium ATCC 25291] gi|41395451|gb|AAS03319.1| hypothetical protein MAP_1002c [Mycobacterium avium subsp. paratuberculosis K-10] Length=257 Score = 444 bits (1141), Expect = 8e-123, Method: Compositional matrix adjust. Identities = 219/257 (86%), Positives = 235/257 (92%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MT MSG + +QRPRQAILGQLPRI+RADGSPIRVLLVDDEPALTNLVKMALHYEGW V++ Sbjct 1 MTVMSGQSAAQRPRQAILGQLPRIYRADGSPIRVLLVDDEPALTNLVKMALHYEGWVVDI 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AH+G+EA+AKFD+ PDVLVLDIMLPDVDGL IL RVR+SD YTPTLFLTARDSVMDRVT Sbjct 61 AHNGREAMAKFDRAAPDVLVLDIMLPDVDGLRILERVRQSDAYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLT+GADDYMTKPFSLEELVARLRGLLRR+S P E L+VGDL +D ASREVTR T Sbjct 121 GLTAGADDYMTKPFSLEELVARLRGLLRRASQQPAPTAETLKVGDLVVDTASREVTRGDT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 P+SLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDS RE Sbjct 181 PVSLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSGRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG+GYMLRP E Sbjct 241 PMIHTVRGVGYMLRPAE 257 >gi|118466262|ref|YP_880424.1| TrcR family transcriptional regulator [Mycobacterium avium 104] gi|118167549|gb|ABK68446.1| two component transcriptional regulator trcr [Mycobacterium avium 104] gi|336461319|gb|EGO40190.1| response regulator with CheY-like receiver domain-containing protein [Mycobacterium avium subsp. paratuberculosis S397] Length=254 Score = 439 bits (1130), Expect = 1e-121, Method: Compositional matrix adjust. Identities = 217/254 (86%), Positives = 233/254 (92%), Gaps = 0/254 (0%) Query 4 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 63 MSG + +QRPRQAILGQLPRI+RADGSPIRVLLVDDEPALTNLVKMALHYEGW V++AH+ Sbjct 1 MSGQSAAQRPRQAILGQLPRIYRADGSPIRVLLVDDEPALTNLVKMALHYEGWVVDIAHN 60 Query 64 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 123 G+EA+AKFD+ PDVLVLDIMLPDVDGL IL RVR+SD YTPTLFLTARDSVMDRVTGLT Sbjct 61 GREAMAKFDRAAPDVLVLDIMLPDVDGLRILERVRQSDAYTPTLFLTARDSVMDRVTGLT 120 Query 124 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 183 +GADDYMTKPFSLEELVARLRGLLRR+S P E L+VGDL +D ASREVTR TP+S Sbjct 121 AGADDYMTKPFSLEELVARLRGLLRRASQQPAPTAETLKVGDLVVDTASREVTRGDTPVS 180 Query 184 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 243 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDS REPMI Sbjct 181 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSGREPMI 240 Query 244 HTVRGIGYMLRPPE 257 HTVRG+GYMLRP E Sbjct 241 HTVRGVGYMLRPAE 254 >gi|254820268|ref|ZP_05225269.1| hypothetical protein MintA_10086 [Mycobacterium intracellulare ATCC 13950] Length=257 Score = 437 bits (1124), Expect = 7e-121, Method: Compositional matrix adjust. Identities = 219/257 (86%), Positives = 234/257 (92%), Gaps = 0/257 (0%) Query 1 MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV 60 MT +GY+ SQRPRQAILGQLPRI+RADGSPIRVLLVDDEPALTNLVKMALHYEGW V++ Sbjct 1 MTATAGYSGSQRPRQAILGQLPRINRADGSPIRVLLVDDEPALTNLVKMALHYEGWVVDI 60 Query 61 AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT 120 AH+G+EA+AKF++V PDVLVLDIMLPDVDGL IL RVR+SDVYTPTLFLTARDSVMDRVT Sbjct 61 AHNGREAMAKFERVNPDVLVLDIMLPDVDGLRILERVRQSDVYTPTLFLTARDSVMDRVT 120 Query 121 GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT 180 GLT+GADDYMTKPFSLEELVARLRGLLRRS P E L VGDL +D ASREVTR T Sbjct 121 GLTAGADDYMTKPFSLEELVARLRGLLRRSGQPPTPTAETLIVGDLRVDTASREVTRGDT 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 +SLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDS RE Sbjct 181 AVSLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSGRE 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG+GYMLRP E Sbjct 241 PMIHTVRGVGYMLRPAE 257 >gi|333992567|ref|YP_004525181.1| two-component transcriptional regulator TrcR [Mycobacterium sp. JDM601] gi|333488535|gb|AEF37927.1| two-component transcriptional regulator TrcR [Mycobacterium sp. JDM601] Length=253 Score = 402 bits (1033), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 204/252 (81%), Positives = 224/252 (89%), Gaps = 1/252 (0%) Query 4 MSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHD 63 MS T + PR+AILGQLPRI+R DGSPIRVLLVDDEPALT+LV MALHYEGW V+VAH+ Sbjct 1 MSDNTDHRSPRKAILGQLPRINRPDGSPIRVLLVDDEPALTSLVTMALHYEGWVVDVAHN 60 Query 64 GQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLT 123 G++A+AKF PD+LVLDIMLPDVDGL+IL+RVRESD Y PTLFLTARDSV DRVTGLT Sbjct 61 GRDAVAKFHSGEPDLLVLDIMLPDVDGLQILQRVRESDAYIPTLFLTARDSVTDRVTGLT 120 Query 124 SGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPIS 183 SGADDYMTKPFSLEELVARLRGLLRRS+ L P DE L VGDLTLDGASR+VT TP+S Sbjct 121 SGADDYMTKPFSLEELVARLRGLLRRSAQLTPPVDEVLTVGDLTLDGASRQVTFGRTPVS 180 Query 184 LSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMI 243 LS+TEFELLRFLMRNP RAL+R EILDRVWNYDFAGRTSIVDLYISYLRKKID+D PMI Sbjct 181 LSTTEFELLRFLMRNPGRALARAEILDRVWNYDFAGRTSIVDLYISYLRKKIDAD-PPMI 239 Query 244 HTVRGIGYMLRP 255 HTVRG+GYML+P Sbjct 240 HTVRGVGYMLKP 251 >gi|120403287|ref|YP_953116.1| two component transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119956105|gb|ABM13110.1| two component transcriptional regulator, winged helix family [Mycobacterium vanbaalenii PYR-1] Length=255 Score = 382 bits (981), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 189/245 (78%), Positives = 216/245 (89%), Gaps = 0/245 (0%) Query 11 QRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAK 70 Q PR+AILG+LPR++RADGSPIRVLLVDDE ALTNLVKMAL YEGW+++VAHD EA+ K Sbjct 9 QGPRRAILGRLPRMYRADGSPIRVLLVDDERALTNLVKMALQYEGWEIDVAHDAAEAVDK 68 Query 71 FDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYM 130 + PD+LVLDIMLPD+DGL +L R+RES YTPTLFLTARDSV DRVTGLT+G DDYM Sbjct 69 YRANTPDLLVLDIMLPDMDGLGVLARLRESGAYTPTLFLTARDSVADRVTGLTAGGDDYM 128 Query 131 TKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFE 190 TKPFSLEELVARLRGLLRRS++L DE+L VGDLTLD ASREVTR G P+SL+STEFE Sbjct 129 TKPFSLEELVARLRGLLRRSAYLAPADDESLSVGDLTLDAASREVTRAGEPVSLTSTEFE 188 Query 191 LLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIG 250 LLR LMRN R+ALSRT+IL +VW+YDF GRTSIVDLY+SYLRKKID+ R+PMIHTVRG+G Sbjct 189 LLRLLMRNQRKALSRTDILRKVWDYDFGGRTSIVDLYVSYLRKKIDAGRDPMIHTVRGVG 248 Query 251 YMLRP 255 YMLRP Sbjct 249 YMLRP 253 >gi|118471523|ref|YP_887235.1| DNA-binding response regulator, PhoP family protein [Mycobacterium smegmatis str. MC2 155] gi|118172810|gb|ABK73706.1| DNA-binding response regulator, PhoP family protein [Mycobacterium smegmatis str. MC2 155] Length=255 Score = 365 bits (938), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 181/253 (72%), Positives = 212/253 (84%), Gaps = 0/253 (0%) Query 5 SGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDG 64 S ++ RPR+AILGQLPR++R DGSPIRVLLVDDE ALTNLV+MAL YEGW ++VAHD Sbjct 3 SAQLKNPRPRRAILGQLPRMYRPDGSPIRVLLVDDERALTNLVQMALQYEGWVIDVAHDA 62 Query 65 QEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTS 124 +A+ K+ PD+LVLDIMLPD DGL +L ++R YTPTLFLTARDSV DRV GLT+ Sbjct 63 AQAVEKYRANLPDLLVLDIMLPDTDGLGVLEQIRSFGTYTPTLFLTARDSVADRVEGLTA 122 Query 125 GADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISL 184 G DDYMTKPFSLEELVARLRGLLRR+++L ADE LRVGDLTLD +S VTR TPI+L Sbjct 123 GGDDYMTKPFSLEELVARLRGLLRRTAYLTPAADETLRVGDLTLDASSHTVTRGDTPIAL 182 Query 185 SSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIH 244 +STEF+LLR LMR+PR+ALSR +IL +VW YDF GRTSIVDLY+SYLRKKID+ REPMIH Sbjct 183 TSTEFQLLRVLMRHPRKALSRDDILRQVWEYDFGGRTSIVDLYVSYLRKKIDTGREPMIH 242 Query 245 TVRGIGYMLRPPE 257 TVRG+GYMLRP + Sbjct 243 TVRGVGYMLRPAD 255 >gi|119717917|ref|YP_924882.1| response regulator receiver [Nocardioides sp. JS614] gi|119538578|gb|ABL83195.1| response regulator receiver [Nocardioides sp. JS614] Length=236 Score = 308 bits (789), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 147/232 (64%), Positives = 181/232 (79%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG+P+RVL+VDDE + L+ MAL YEGW V AH G +A+A + PD +VLDI Sbjct 3 LARPDGTPLRVLVVDDEANIAELISMALRYEGWQVRAAHTGSKAVAAAKEFRPDAVVLDI 62 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE+LRR+R +D P +FLTARD+V DRV GLT+G DDY+TKPFSLEELVARL Sbjct 63 MLPDFDGLEVLRRIRSTDPSVPVVFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVARL 122 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 RGL+RR+ + A L VGDL LD SREV R G ++L++TEFELLRFLMRNPRR L Sbjct 123 RGLMRRAGAQQATASSTLVVGDLELDEDSREVFRAGREVTLTATEFELLRFLMRNPRRVL 182 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ EPMIHT+RG GY+L+P Sbjct 183 SKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGHEPMIHTMRGAGYVLKP 234 >gi|269796544|ref|YP_003315999.1| CheY-like receiver domain/winged-helix DNA-binding domain-containing response regulator [Sanguibacter keddieii DSM 10542] gi|269098729|gb|ACZ23165.1| response regulator with CheY-like receiver domain and winged-helix DNA-binding domain [Sanguibacter keddieii DSM 10542] Length=271 Score = 306 bits (785), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 152/235 (65%), Positives = 184/235 (79%), Gaps = 0/235 (0%) Query 21 LPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLV 80 LPR+ RADGSP+RVL+VDDEP L L+ AL YEGWDV A DGQ A+ + PDV+V Sbjct 12 LPRLTRADGSPLRVLVVDDEPNLAELLTSALRYEGWDVSTALDGQTAVRLARETVPDVIV 71 Query 81 LDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELV 140 LDIML D+DGLE+LRR+R+ P LFLTARDSV DRV GLT+G DDY+TKPFSLEE+V Sbjct 72 LDIMLGDIDGLEVLRRIRQQQEGVPVLFLTARDSVEDRVAGLTAGGDDYVTKPFSLEEVV 131 Query 141 ARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPR 200 ARLRGLLRR+ + L VGDLTLD S EV R G I L++TEFELLR+LMRN R Sbjct 132 ARLRGLLRRAGASAARDEARLVVGDLTLDEDSHEVDRAGQEIHLTATEFELLRYLMRNAR 191 Query 201 RALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 R +S+++ILDRVW YDF G+ +IV+LYISYLR+KID+ REPMIHT+RG+GY+L+P Sbjct 192 RVMSKSQILDRVWQYDFGGQANIVELYISYLRRKIDAGREPMIHTLRGVGYVLKP 246 >gi|148273950|ref|YP_001223511.1| putative two-component system, response regulator [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147831880|emb|CAN02850.1| putative two-component system, response regulator [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=257 Score = 305 bits (781), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 153/257 (60%), Positives = 196/257 (77%), Gaps = 8/257 (3%) Query 2 TTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVA 61 T SG+ + P+ PR+ RADGSPIRVL+VDDE +LT+L++MAL YEGW + A Sbjct 8 TPPSGFQPAAAPQ-------PRLTRADGSPIRVLVVDDEASLTDLLQMALRYEGWQIRTA 60 Query 62 HDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTG 121 +G +A+A + PD +VLDIMLPD+DGL++L R+R P LFLTA+DS+ DR+ G Sbjct 61 ENGHQALAAAREFKPDAVVLDIMLPDLDGLQVLSRLRADAEDIPVLFLTAKDSLDDRLAG 120 Query 122 LTSGADDYMTKPFSLEELVARLRGLLRRSSH-LERPADEALRVGDLTLDGASREVTRDGT 180 LT+G DDY+TKPFSLEE+VARLRGL+RRS+ + D +RVGDLTLD S EV R G Sbjct 121 LTAGGDDYVTKPFSLEEVVARLRGLIRRSTLVVSDSVDPVIRVGDLTLDEDSHEVARAGD 180 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PI L++TEFELLR+LMRNPRR LS+ +ILDRVW+YDF G++S+V++YISYLR+KID+ R Sbjct 181 PIELTATEFELLRYLMRNPRRVLSKLQILDRVWSYDFGGKSSVVEIYISYLRRKIDAGRN 240 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG GYML+ E Sbjct 241 PMIHTVRGSGYMLKAAE 257 >gi|170780989|ref|YP_001709321.1| putative two component response regulator [Clavibacter michiganensis subsp. sepedonicus] gi|169155557|emb|CAQ00673.1| putative two component response regulator [Clavibacter michiganensis subsp. sepedonicus] Length=269 Score = 305 bits (781), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 153/257 (60%), Positives = 196/257 (77%), Gaps = 8/257 (3%) Query 2 TTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVA 61 T SG+ + P+ PR+ RADGSPIRVL+VDDE +LT+L++MAL YEGW + A Sbjct 20 ATPSGFQPAAAPQ-------PRLTRADGSPIRVLVVDDEASLTDLLQMALRYEGWQIRTA 72 Query 62 HDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTG 121 +G +A+A + PD +VLDIMLPD+DGL++L R+R P LFLTA+DS+ DR+ G Sbjct 73 ENGHQALAAAREFKPDAVVLDIMLPDLDGLQVLSRLRADAEDIPVLFLTAKDSLDDRLAG 132 Query 122 LTSGADDYMTKPFSLEELVARLRGLLRRSSH-LERPADEALRVGDLTLDGASREVTRDGT 180 LT+G DDY+TKPFSLEE+VARLRGL+RRS+ + D +RVGDLTLD S EV R G Sbjct 133 LTAGGDDYVTKPFSLEEVVARLRGLIRRSTLVVSDTVDPVIRVGDLTLDEDSHEVARAGD 192 Query 181 PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE 240 PI L++TEFELLR+LMRNPRR LS+ +ILDRVW+YDF G++S+V++YISYLR+KID+ R Sbjct 193 PIELTATEFELLRYLMRNPRRVLSKLQILDRVWSYDFGGKSSVVEIYISYLRRKIDAGRN 252 Query 241 PMIHTVRGIGYMLRPPE 257 PMIHTVRG GYML+ E Sbjct 253 PMIHTVRGSGYMLKAAE 269 >gi|336116252|ref|YP_004571018.1| two-component system response regulator [Microlunatus phosphovorus NM-1] gi|334684030|dbj|BAK33615.1| two-component system response regulator [Microlunatus phosphovorus NM-1] Length=248 Score = 300 bits (769), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 144/232 (63%), Positives = 179/232 (78%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 I R DG+ IR+L VDDE +LT L+ MA+ YEGW V A G EA+ +V PD +VLD+ Sbjct 15 ITRPDGTAIRILAVDDESSLTELLSMAMRYEGWQVSTAASGSEAVKAAREVRPDAIVLDM 74 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR D P +FLTA+D+V DR++GLT+G DDY+TKPFSLEE++ARL Sbjct 75 MLPDFDGLEVMRRVRAEDPDVPVIFLTAKDAVADRISGLTAGGDDYVTKPFSLEEVIARL 134 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS ++ L VGDLTLD S EV R G I L++TEFELLR+LMRNPRR L Sbjct 135 RALLRRSGAATGRSESLLVVGDLTLDEDSHEVARAGDAIQLTATEFELLRYLMRNPRRVL 194 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ ++V+LYISYLRKKID++R PMIHT+RG GY+LRP Sbjct 195 SKAQILDRVWNYDFGGQANVVELYISYLRKKIDANRAPMIHTMRGAGYVLRP 246 >gi|84495357|ref|ZP_00994476.1| putative two component system response regulator [Janibacter sp. HTCC2649] gi|84384850|gb|EAQ00730.1| putative two component system response regulator [Janibacter sp. HTCC2649] Length=244 Score = 300 bits (768), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 141/235 (60%), Positives = 183/235 (78%), Gaps = 0/235 (0%) Query 23 RIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLD 82 ++ R DGSP+RVL+VDDE LT L+ MAL YEGW+V A G +A+ + PD +VLD Sbjct 10 KLQRPDGSPVRVLVVDDESNLTELLSMALRYEGWEVRAAATGLKAVKAAREFQPDAVVLD 69 Query 83 IMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVAR 142 +MLPD DG+E+LRR+R + P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VAR Sbjct 70 MMLPDFDGMEVLRRMRADNDAVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVAR 129 Query 143 LRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 LR L+RR++ + + + VGDLT+D S EVTR G I L++TEFELLR+LMRNP+R Sbjct 130 LRALMRRTTVVADESSSIIAVGDLTMDEDSHEVTRGGVEIHLTATEFELLRYLMRNPKRV 189 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ R PMIHT+RG+GY+L+P E Sbjct 190 LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRTPMIHTMRGVGYVLKPAE 244 >gi|88856021|ref|ZP_01130683.1| two-component system, regulatory protein [marine actinobacterium PHSC20C1] gi|88814888|gb|EAR24748.1| two-component system, regulatory protein [marine actinobacterium PHSC20C1] Length=250 Score = 299 bits (765), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 149/237 (63%), Positives = 186/237 (79%), Gaps = 1/237 (0%) Query 22 PRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVL 81 PR+ RADG+ IR ++VDDE +LT+L+ MAL YEGWDV +A DG +A+A + PDV+VL Sbjct 14 PRLSRADGTAIRAVVVDDEDSLTDLLSMALRYEGWDVRLASDGPQALATIREFRPDVVVL 73 Query 82 DIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVA 141 DIM+P +DGL +L R+R + TP LFLTA+DSV DR+ GLT G DDY+TKPFSLEELVA Sbjct 74 DIMMPGLDGLAVLTRLRADGIQTPILFLTAKDSVDDRIAGLTVGGDDYVTKPFSLEELVA 133 Query 142 RLRGLLRRSS-HLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPR 200 RLR LLRRSS + ++ + VGDLTLD ++ EV R GT + L++TEFELLR+LMRNPR Sbjct 134 RLRALLRRSSITIAGDSNPVIEVGDLTLDESTYEVARGGTRVELTATEFELLRYLMRNPR 193 Query 201 RALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 R LSR +ILDRVW+YDF GR S+V++YISYLRKKID PMIHTVRG+GYML+ E Sbjct 194 RVLSRAQILDRVWSYDFGGRASVVEIYISYLRKKIDVLGPPMIHTVRGVGYMLKVAE 250 >gi|326333582|ref|ZP_08199821.1| DNA-binding response regulator TrcR [Nocardioidaceae bacterium Broad-1] gi|325948598|gb|EGD40699.1| DNA-binding response regulator TrcR [Nocardioidaceae bacterium Broad-1] Length=244 Score = 299 bits (765), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 145/234 (62%), Positives = 179/234 (77%), Gaps = 0/234 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DGSP+RVL+VDDE + L+ MAL YEGW+V AH G +A++ PD +VLD Sbjct 11 LTRLDGSPLRVLVVDDEVNIAELIMMALRYEGWEVAAAHTGTKAVSAARDFTPDAIVLDW 70 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE+LRRVR ++ P LFLTA+D+V DRV GLT+G DDY+TKPFSLEELVARL Sbjct 71 MLPDFDGLEVLRRVRSTNPAVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEELVARL 130 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R L+RR+ + VGDLT+D SREV R G ISL++TEFELLRFLMRNPRR L Sbjct 131 RALMRRAGATRIEEHSVIHVGDLTMDEDSREVRRAGEEISLTATEFELLRFLMRNPRRVL 190 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 S+ +ILDRVW+YDF G+ ++V+LYISYLRKKID+ REPMIHT+RG GY+L+ E Sbjct 191 SKAQILDRVWSYDFGGQANVVELYISYLRKKIDAGREPMIHTMRGAGYVLKAAE 244 >gi|330468634|ref|YP_004406377.1| two component transcriptional regulator [Verrucosispora maris AB-18-032] gi|328811605|gb|AEB45777.1| two component transcriptional regulator [Verrucosispora maris AB-18-032] Length=247 Score = 299 bits (765), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 146/235 (63%), Positives = 180/235 (77%), Gaps = 1/235 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG +RVL+VDDEP LT+L+ MAL YEGW V A DG AI + PD +VLD+ Sbjct 13 LRRPDGEAVRVLVVDDEPTLTDLLSMALRYEGWQVRTAGDGMGAIRAARQFQPDAVVLDV 72 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD+DG E+LR++RE D P LFLTARD+V +RV GLT G DDY+TKPFSLEE++ARL Sbjct 73 MLPDLDGFEVLRKLREDDATVPVLFLTARDAVEERVAGLTVGGDDYVTKPFSLEEVIARL 132 Query 144 RGLLRRSSH-LERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 R LLRRS + D L VGDLTL+ S EV R G I+L++TEFELLR+LMRNPRR Sbjct 133 RALLRRSGFAVTARQDAVLTVGDLTLNEESHEVRRSGQLITLTATEFELLRYLMRNPRRV 192 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ R+PMIHT+RG GY+L+P E Sbjct 193 LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRQPMIHTLRGAGYLLKPAE 247 >gi|324999382|ref|ZP_08120494.1| two component transcriptional regulator, winged helix family protein [Pseudonocardia sp. P1] Length=246 Score = 298 bits (764), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 148/233 (64%), Positives = 178/233 (77%), Gaps = 0/233 (0%) Query 23 RIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLD 82 ++ RADGSPIRVL+VDDE L++L+ MAL YEGW+V A DG A+ + PD +VLD Sbjct 11 QLRRADGSPIRVLVVDDESTLSDLLSMALRYEGWEVRTAGDGATAVRHAREFRPDAIVLD 70 Query 83 IMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVAR 142 +MLPDVDG E+LRRVR P LFLTARD+V DRV GLT+G DDY+TKPFSLEELVAR Sbjct 71 VMLPDVDGFEVLRRVRAGTPEVPVLFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVAR 130 Query 143 LRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 LRGLLRR+ L VGDL LD + EV R PI L++TEFELLR+LMRNPRR Sbjct 131 LRGLLRRAGMAAAQRSSELVVGDLVLDEDAHEVRRADRPIELTATEFELLRYLMRNPRRV 190 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 LS+ +ILDRVWNYDF G++++V+LY+SYLRKKID+ PMIHTVRG GY+LRP Sbjct 191 LSKAQILDRVWNYDFGGQSNVVELYVSYLRKKIDAGYAPMIHTVRGAGYVLRP 243 >gi|331698780|ref|YP_004335019.1| winged helix family two component transcriptional regulator [Pseudonocardia dioxanivorans CB1190] gi|326953469|gb|AEA27166.1| two component transcriptional regulator, winged helix family [Pseudonocardia dioxanivorans CB1190] Length=247 Score = 297 bits (761), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 147/233 (64%), Positives = 178/233 (77%), Gaps = 0/233 (0%) Query 23 RIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLD 82 R+ RADGS +RVL+VDDE L++L+ MAL YEGWDV DG A+ + PD +VLD Sbjct 11 RLQRADGSAVRVLVVDDEATLSDLLGMALRYEGWDVRTEADGASAVRAAREFRPDAVVLD 70 Query 83 IMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVAR 142 +MLPD+DGLE+LRR+R P LFLTA+D+V DRV GLT+G DDY+TKPFSLEELVAR Sbjct 71 VMLPDLDGLEVLRRMRADTPDVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEELVAR 130 Query 143 LRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 LRGLLRRS L VGDLTLD S EV R + L++TEFELLRFLMRNPRR Sbjct 131 LRGLLRRSGMTAAQQGSELAVGDLTLDEDSHEVRRGDVEVDLTATEFELLRFLMRNPRRV 190 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 LS+ +ILDRVW+YDF G++++V+LYISYLRKKID+ R PMIHTVRG GY+L+P Sbjct 191 LSKAQILDRVWHYDFGGQSNVVELYISYLRKKIDNGRAPMIHTVRGAGYVLKP 243 >gi|315094756|gb|EFT66732.1| response regulator receiver domain protein [Propionibacterium acnes HL060PA1] Length=243 Score = 297 bits (761), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 143/242 (60%), Positives = 183/242 (76%), Gaps = 0/242 (0%) Query 16 AILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVG 75 A+ Q PR ADGSPIRVL+V+DEP+LT L+ MA+ YEGWDV A+ G A+ + Sbjct 2 ALPTQPPRFTGADGSPIRVLVVEDEPSLTGLLSMAMRYEGWDVTTANSGAHAVHEAQATR 61 Query 76 PDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFS 135 PDV+VLD+ LPD DGLE++R++R + P +FLTA+D++ R+ GLT+G DDY+TKPFS Sbjct 62 PDVIVLDMRLPDFDGLEVMRQIRMNQPTVPAVFLTAKDAISGRIAGLTAGGDDYITKPFS 121 Query 136 LEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFL 195 LEE++ARLR LLRR+ E +D L VGDLTLD SREV R G I L++TEFELLR+ Sbjct 122 LEEVIARLRTLLRRAGATEPKSDSMLTVGDLTLDEDSREVRRAGEEIHLTTTEFELLRYF 181 Query 196 MRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 MRNP+R LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID PMIHT+RG GY+L+P Sbjct 182 MRNPKRVLSKAQILDRVWNYDFRGQANVVELYISYLRKKIDRGHTPMIHTMRGAGYVLKP 241 Query 256 PE 257 E Sbjct 242 AE 243 >gi|159037874|ref|YP_001537127.1| two component transcriptional regulator [Salinispora arenicola CNS-205] gi|157916709|gb|ABV98136.1| two component transcriptional regulator, winged helix family [Salinispora arenicola CNS-205] Length=248 Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 146/233 (63%), Positives = 180/233 (78%), Gaps = 1/233 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG P+RVL+VDDEP LT+L+ MAL YEGW V A +G A++ + PD +VLD+ Sbjct 14 LRRPDGQPVRVLVVDDEPTLTDLLSMALRYEGWQVRTAGNGMAALSTARQFQPDAVVLDV 73 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD+DG +LRR+RE P LFLTARD+V DRV GLT G DDY+TKPFSLEE++ARL Sbjct 74 MLPDLDGFAVLRRLREVAPTVPVLFLTARDAVEDRVAGLTVGGDDYVTKPFSLEEVIARL 133 Query 144 RGLLRRSSHLERPADEA-LRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 R LLRRS EA L VGDL+LD S EV+RDG I+L++TEFELLR+LMRNPRR Sbjct 134 RALLRRSGFAIAARHEAVLTVGDLSLDEDSHEVSRDGQLINLTATEFELLRYLMRNPRRV 193 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ R PMIHT+RG GY+L+P Sbjct 194 LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRAPMIHTLRGAGYVLKP 246 >gi|329946290|ref|ZP_08293884.1| response regulator MprA [Actinomyces sp. oral taxon 170 str. F0386] gi|328527582|gb|EGF54577.1| response regulator MprA [Actinomyces sp. oral taxon 170 str. F0386] Length=248 Score = 294 bits (753), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 146/232 (63%), Positives = 177/232 (77%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + RADGSP+RVL+VDDE L +L+ AL YEGW+V A G A+ ++ PDV+VLDI Sbjct 9 LTRADGSPLRVLVVDDEQMLADLLASALRYEGWEVTTAGSGIAAVRSAQEIDPDVIVLDI 68 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARL Sbjct 69 MLPDFDGLEVMRRVRGHSPNVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVARL 128 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS E D L VGDL +D S EV R I L++TEFELLR+LMRNPRR L Sbjct 129 RALLRRSGASEEKPDSLLEVGDLRMDEDSHEVWRGEDEIQLTATEFELLRYLMRNPRRVL 188 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ +IV+LYISYLR+KID REPMIHT+RG+GY+L+P Sbjct 189 SKPQILDRVWNYDFGGQANIVELYISYLRRKIDKGREPMIHTMRGVGYVLKP 240 >gi|145594662|ref|YP_001158959.1| response regulator receiver [Salinispora tropica CNB-440] gi|145303999|gb|ABP54581.1| response regulator receiver [Salinispora tropica CNB-440] Length=252 Score = 294 bits (753), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 145/235 (62%), Positives = 178/235 (76%), Gaps = 1/235 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG P+RVL+VDDE L +L+ MAL YEGW V A +G A++ + PD +VLD+ Sbjct 18 LRRPDGQPVRVLVVDDESTLADLLSMALRYEGWQVRTAGNGMAALSAARQFQPDAVVLDV 77 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD+DG +LRR+RE P LFLTARD+V DRV GLT G DDY+TKPFSLEE++ARL Sbjct 78 MLPDLDGFAVLRRLREVAPTVPVLFLTARDAVEDRVAGLTVGGDDYVTKPFSLEEVIARL 137 Query 144 RGLLRRSSHLERPADEA-LRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 R LLRRS EA L VGDL+LD S EV+RDG I+L++TEFELLR+LMRNPRR Sbjct 138 RALLRRSGFAVTARQEAVLTVGDLSLDEDSHEVSRDGQLINLTATEFELLRYLMRNPRRV 197 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID R PMIHT+RG GY+L+P E Sbjct 198 LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDVGRAPMIHTLRGAGYVLKPAE 252 >gi|111220170|ref|YP_710964.1| putative two-component system response regulator [Frankia alni ACN14a] gi|111147702|emb|CAJ59359.1| Putative two-component system response regulator (partial match) [Frankia alni ACN14a] Length=358 Score = 294 bits (752), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 151/249 (61%), Positives = 184/249 (74%), Gaps = 6/249 (2%) Query 10 SQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIA 69 S R R I +L R+ P+RVL+VDDE L L+ MAL YEGW+V A DG+ A+ Sbjct 2 SLRLRPGIREKLSRMQ-----PVRVLVVDDETTLAELLSMALRYEGWEVRSAGDGRGALR 56 Query 70 KFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDY 129 + PD +VLDIMLPD+DGLE+LRR+R P LFLTARD+V DRV GLT+G DDY Sbjct 57 LAREFRPDAVVLDIMLPDMDGLEVLRRLRAESPDVPVLFLTARDAVEDRVAGLTAGGDDY 116 Query 130 MTKPFSLEELVARLRGLLRRSSHLERPADEA-LRVGDLTLDGASREVTRDGTPISLSSTE 188 +TKPFSLEELVARLRGL+RR++ A L VGDLT+D SREV R G P+ L++TE Sbjct 117 VTKPFSLEELVARLRGLMRRAARTTEALQGARLVVGDLTMDEESREVARGGVPVHLTATE 176 Query 189 FELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRG 248 FELLRF MRNPRR LS+ +ILDRVWNYDF G+ ++V+LY+SYLRKKID+ R PMIHT+RG Sbjct 177 FELLRFFMRNPRRVLSKAQILDRVWNYDFGGQANVVELYVSYLRKKIDAGRPPMIHTMRG 236 Query 249 IGYMLRPPE 257 GY+LRP E Sbjct 237 AGYVLRPAE 245 >gi|326772529|ref|ZP_08231813.1| DNA-binding response regulator TrcR [Actinomyces viscosus C505] gi|326637161|gb|EGE38063.1| DNA-binding response regulator TrcR [Actinomyces viscosus C505] Length=248 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 146/232 (63%), Positives = 177/232 (77%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + RADGSP+RVL+VDDE L +L+ AL YEGW+V A G A+ ++ PDV+VLDI Sbjct 9 LTRADGSPLRVLVVDDEQMLADLLASALRYEGWEVTTAGTGIAAVRSAQEIDPDVIVLDI 68 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARL Sbjct 69 MLPDFDGLEVMRRVRGHRPNVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVARL 128 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS E L VGDL +D S EV R G I L++TEFELLR+LMRNPRR L Sbjct 129 RALLRRSGASEEKPASILEVGDLRMDEDSHEVWRGGDEIQLTATEFELLRYLMRNPRRVL 188 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ +IV+LYISYLR+KID REPMIHT+RG+GY+L+P Sbjct 189 SKPQILDRVWNYDFGGQANIVELYISYLRRKIDKGREPMIHTMRGVGYVLKP 240 >gi|29830741|ref|NP_825375.1| two-component system response regulator [Streptomyces avermitilis MA-4680] gi|29607854|dbj|BAC71910.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680] Length=269 Score = 293 bits (749), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 143/230 (63%), Positives = 180/230 (79%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DGQ A+ + PD +VLD+ML Sbjct 37 RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAVQTAREFRPDAVVLDMML 96 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 97 PDMDGLTVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 156 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R +D L VGDLTLD S EV+R G I L++TEFELLRFLMRNPRR LS+ Sbjct 157 LIRRSGAADRRSDSMLVVGDLTLDEDSHEVSRSGENIHLTATEFELLRFLMRNPRRVLSK 216 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 217 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 266 >gi|289770395|ref|ZP_06529773.1| two component system response regulator [Streptomyces lividans TK24] gi|289700594|gb|EFD68023.1| two component system response regulator [Streptomyces lividans TK24] Length=285 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 143/230 (63%), Positives = 178/230 (78%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DG A+ PD +VLD+ML Sbjct 53 RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGHGAVQTARDFRPDAVVLDMML 112 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 113 PDMDGLSVLGRLRRDLPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 172 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R +D L VGDLTLD S EVTR G I L++TEFELLRFLMRNPRR LS+ Sbjct 173 LIRRSGAADRRSDSVLVVGDLTLDEDSHEVTRSGDGIHLTATEFELLRFLMRNPRRVLSK 232 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 233 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 282 >gi|317126455|ref|YP_004100567.1| transcriptional regulator [Intrasporangium calvum DSM 43043] gi|315590543|gb|ADU49840.1| two component transcriptional regulator, winged helix family [Intrasporangium calvum DSM 43043] Length=248 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 144/233 (62%), Positives = 182/233 (79%), Gaps = 0/233 (0%) Query 23 RIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLD 82 R+ R DGS +RVL+VDDEP LT L+ MAL YEGW+V A G +A+ + PD +VLD Sbjct 14 RLQRLDGSAVRVLVVDDEPNLTELLGMALRYEGWEVRAAATGMQAVRAAREFDPDAVVLD 73 Query 83 IMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVAR 142 +MLPD DGLE+LRR+R + P LFLTA+D+V DRV+GLT+G DDY+TKPFSLEE+VAR Sbjct 74 MMLPDFDGLEVLRRMRTDNPNVPVLFLTAKDAVEDRVSGLTAGGDDYVTKPFSLEEVVAR 133 Query 143 LRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 +R L+RR++ +D L VGDLTLD S EV R G I L++TEFELLR+LMRNPRR Sbjct 134 VRALMRRTTMSVSSSDSVLVVGDLTLDEDSHEVYRAGEEIHLTATEFELLRYLMRNPRRV 193 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKK+D+ R+PMIHT+RG GY+LRP Sbjct 194 LSKAQILDRVWNYDFGGQANVVELYISYLRKKVDAGRDPMIHTMRGAGYVLRP 246 >gi|302559780|ref|ZP_07312122.1| DNA-binding response regulator TrcR [Streptomyces griseoflavus Tu4000] gi|302477398|gb|EFL40491.1| DNA-binding response regulator TrcR [Streptomyces griseoflavus Tu4000] Length=249 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 144/230 (63%), Positives = 180/230 (79%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DGQ A+ + PD +VLD+ML Sbjct 17 RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGQGALRTAREFRPDAVVLDMML 76 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL IL R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 77 PDMDGLAILGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 136 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R ++ L VGDLTLD S EVTR G I L++TEFELLRFLMRNPRR LS+ Sbjct 137 LIRRSGAADRRSESMLVVGDLTLDEDSHEVTRGGDGIHLTATEFELLRFLMRNPRRVLSK 196 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 197 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 246 >gi|21222423|ref|NP_628202.1| two component system response regulator [Streptomyces coelicolor A3(2)] gi|13122184|emb|CAC32360.1| putative two component system response regulator [Streptomyces coelicolor A3(2)] Length=271 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 143/230 (63%), Positives = 178/230 (78%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DG A+ PD +VLD+ML Sbjct 39 RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGHGAVQTARDFRPDAVVLDMML 98 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 99 PDMDGLSVLGRLRRDLPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 158 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R +D L VGDLTLD S EVTR G I L++TEFELLRFLMRNPRR LS+ Sbjct 159 LIRRSGAADRRSDSVLVVGDLTLDEDSHEVTRSGDGIHLTATEFELLRFLMRNPRRVLSK 218 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 219 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 268 >gi|302552564|ref|ZP_07304906.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces viridochromogenes DSM 40736] gi|302470182|gb|EFL33275.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces viridochromogenes DSM 40736] Length=268 Score = 292 bits (747), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 144/230 (63%), Positives = 179/230 (78%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DGQ AI PD +VLD+ML Sbjct 36 RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAIQSARDFRPDAVVLDMML 95 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 96 PDMDGLAVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 155 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R ++ L VGDLTLD S EVTR G I L++TEFELLRFLMRNPRR LS+ Sbjct 156 LIRRSGAADRRSESMLVVGDLTLDEDSHEVTRAGDNIHLTATEFELLRFLMRNPRRVLSK 215 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 216 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 265 >gi|302544103|ref|ZP_07296445.1| DNA-binding response regulator TrcR [Streptomyces hygroscopicus ATCC 53653] gi|302461721|gb|EFL24814.1| DNA-binding response regulator TrcR [Streptomyces himastatinicus ATCC 53653] Length=290 Score = 292 bits (747), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 144/232 (63%), Positives = 179/232 (78%), Gaps = 0/232 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE AL +L+ MAL YEGW+V A DG EAI ++ PD +VLD+ML Sbjct 59 RPDGSPVRVLVVDDESALADLLSMALRYEGWEVRTAGDGAEAIRTTRELRPDAVVLDVML 118 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTARD+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 119 PDMDGLTVLGRLRRELPEVPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 178 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 LLRRS ++ L VGDL LD S EV+R G I L++TEFELLR+LMRNPRR LS+ Sbjct 179 LLRRSGAAAARSESVLAVGDLVLDEDSHEVSRAGQEIHLTATEFELLRYLMRNPRRVLSK 238 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ R PMIHT RG GY+++P E Sbjct 239 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGRSPMIHTRRGAGYLIKPGE 290 >gi|302867311|ref|YP_003835948.1| response regulator receiver [Micromonospora aurantiaca ATCC 27029] gi|315506283|ref|YP_004085170.1| winged helix family two component transcriptional regulator [Micromonospora sp. L5] gi|302570170|gb|ADL46372.1| response regulator receiver [Micromonospora aurantiaca ATCC 27029] gi|315412902|gb|ADU11019.1| two component transcriptional regulator, winged helix family [Micromonospora sp. L5] Length=246 Score = 292 bits (747), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 145/235 (62%), Positives = 177/235 (76%), Gaps = 1/235 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG P+RVL+VDDEP LT+L+ MAL YEGW V A G A+ + PD +VLD+ Sbjct 12 LRRPDGEPVRVLVVDDEPTLTDLLSMALRYEGWQVATAGSGMAAVTTARQFRPDAVVLDV 71 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD+DG ++LRR+RE P LFLTARD+V +RV GLT G DDY+TKPFSLEE++ARL Sbjct 72 MLPDLDGFQVLRRLREQFPSVPVLFLTARDAVEERVAGLTVGGDDYVTKPFSLEEVIARL 131 Query 144 RGLLRRSSHLERPADEA-LRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRA 202 R LLRRS EA L VGDLTLD S EV R I+L++TEFELLR+LMRNPRR Sbjct 132 RALLRRSGFAVAARQEAVLTVGDLTLDEDSHEVRRGDDLITLTATEFELLRYLMRNPRRV 191 Query 203 LSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ R PMIHT+RG GY+L+P E Sbjct 192 LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRAPMIHTLRGAGYVLKPAE 246 >gi|294630229|ref|ZP_06708789.1| DNA-binding response regulator TrcR [Streptomyces sp. e14] gi|292833562|gb|EFF91911.1| DNA-binding response regulator TrcR [Streptomyces sp. e14] Length=269 Score = 291 bits (746), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 141/230 (62%), Positives = 180/230 (79%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DGQ A+ + PD +VLD+ML Sbjct 37 RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAVQTAREFRPDAVVLDMML 96 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 97 PDMDGLTVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 156 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RR+ +R ++ L VGDLTLD S EV+R G I L++TEFELLRFLMRNPRR LS+ Sbjct 157 LIRRAGAADRRSESVLVVGDLTLDEDSHEVSRGGQDIHLTATEFELLRFLMRNPRRVLSK 216 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 217 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 266 >gi|50843487|ref|YP_056714.1| putative two-component system response regulator [Propionibacterium acnes KPA171202] gi|335053397|ref|ZP_08546238.1| response regulator MprA [Propionibacterium sp. 434-HC2] gi|50841089|gb|AAT83756.1| putative two-component system response regulator [Propionibacterium acnes KPA171202] gi|315107835|gb|EFT79811.1| response regulator receiver domain protein [Propionibacterium acnes HL030PA1] gi|333767085|gb|EGL44346.1| response regulator MprA [Propionibacterium sp. 434-HC2] gi|335278443|gb|AEH30348.1| putative two-component system response regulator [Propionibacterium acnes 6609] Length=243 Score = 291 bits (745), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 141/238 (60%), Positives = 178/238 (75%), Gaps = 0/238 (0%) Query 20 QLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVL 79 Q R RADGSPIRVL+V+DEP+LT L+ MA+ YEGWDV A+ G A+ + PDV+ Sbjct 6 QPSRFTRADGSPIRVLVVEDEPSLTGLLSMAMRYEGWDVTTANSGAHAVHEAQATRPDVI 65 Query 80 VLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEEL 139 VLD+ L D DGLE++R++R + +FLTA+D+ R+ GLT+G DDY+TKPFSLEE+ Sbjct 66 VLDMRLSDFDGLEVMRQIRINQPTVRAVFLTAKDAASGRIAGLTAGGDDYVTKPFSLEEV 125 Query 140 VARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNP 199 +ARLR LLRRS E D L VGDLTLD SREV R G I L++TEFELLR+ MRNP Sbjct 126 IARLRALLRRSGATEPKPDSMLTVGDLTLDENSREVRRAGEEIHLTTTEFELLRYFMRNP 185 Query 200 RRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 +R LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID +PMIHT+RG GY+L+P E Sbjct 186 KRVLSKAQILDRVWNYDFRGQANVVELYISYLRKKIDRGHKPMIHTMRGAGYVLKPAE 243 >gi|152966980|ref|YP_001362764.1| winged helix family two component transcriptional regulator [Kineococcus radiotolerans SRS30216] gi|151361497|gb|ABS04500.1| two component transcriptional regulator, winged helix family [Kineococcus radiotolerans SRS30216] Length=273 Score = 291 bits (745), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 141/234 (61%), Positives = 178/234 (77%), Gaps = 0/234 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG+ +RVL+VDDE L+ L+ M L YEGW+V+ A +G +A+ PD ++LDI Sbjct 33 LTRPDGTALRVLVVDDESTLSELLSMTLRYEGWEVQTAGNGLDAVRAARSFRPDAVILDI 92 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD+DGLE+LRR+R P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARL Sbjct 93 MLPDIDGLEVLRRLRADATDVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVARL 152 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS + + L VGDL LD S EVTR G I L++TEFELLR+LMRNPRR L Sbjct 153 RSLLRRSGLVAAKQEPVLAVGDLVLDEDSHEVTRAGQEIRLTATEFELLRYLMRNPRRVL 212 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 S+ +ILDRVWNYDF G+ +IV+LY+SYLR+KID+ R PMIHTVRG GY+L+P + Sbjct 213 SKAQILDRVWNYDFGGQANIVELYVSYLRRKIDAGRNPMIHTVRGAGYVLKPAD 266 >gi|323359410|ref|YP_004225806.1| response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Microbacterium testaceum StLB037] gi|323275781|dbj|BAJ75926.1| response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Microbacterium testaceum StLB037] Length=244 Score = 291 bits (744), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 142/233 (61%), Positives = 182/233 (79%), Gaps = 1/233 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGS +RVL+VDDE LT+L+ MAL EGWDV A G +A+ PD +VLDIM+ Sbjct 12 RPDGSALRVLVVDDEQMLTDLLSMALRMEGWDVRTAGSGFDALQAARDFAPDAMVLDIMM 71 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DG+ +L+R+R S P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARLRG Sbjct 72 PDLDGMAVLQRLRHSGNDVPVLFLTAKDAVADRVAGLTAGGDDYVTKPFSLEEVVARLRG 131 Query 146 LLRRS-SHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALS 204 L+RR+ + L R ++ LRVGDL+L+ S EV R G I L++TEFELLRFLMRN RR +S Sbjct 132 LMRRAGTALTRDSEPILRVGDLSLNEDSHEVVRGGHEIELTATEFELLRFLMRNQRRVVS 191 Query 205 RTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 + +ILDRVWNYDF GR+S+V+LYISYLRKKID+ +P+IHTVRG+GYM++ P+ Sbjct 192 KAQILDRVWNYDFGGRSSVVELYISYLRKKIDAGHDPLIHTVRGVGYMIKAPQ 244 >gi|297200795|ref|ZP_06918192.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces sviceus ATCC 29083] gi|197712366|gb|EDY56400.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces sviceus ATCC 29083] Length=269 Score = 291 bits (744), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 142/230 (62%), Positives = 179/230 (78%), Gaps = 0/230 (0%) Query 26 RADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDIML 85 R DGSP+RVL+VDDE ++T L+ MAL YEGW + A DG A+ + PD +VLD+ML Sbjct 37 RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGTGAVQTAREFRPDAVVLDMML 96 Query 86 PDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRG 145 PD+DGL +L R+R P LFLTA+D+V DR+ GLT+G DDY+TKPFSLEE+VARLRG Sbjct 97 PDMDGLAVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG 156 Query 146 LLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSR 205 L+RRS +R +D L VGDLTLD S EV+R G I L++TEFELLRFLMRNPRR LS+ Sbjct 157 LIRRSGAADRRSDSVLVVGDLTLDEDSHEVSRAGENIHLTATEFELLRFLMRNPRRVLSK 216 Query 206 TEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 +ILDRVW+YDF G+ ++V+LYISYLR+KID+ REPMIHT RG GY+++P Sbjct 217 AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKP 266 >gi|325066524|ref|ZP_08125197.1| two component system response regulator [Actinomyces oris K20] Length=248 Score = 291 bits (744), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 145/232 (63%), Positives = 176/232 (76%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + RADGSP+RVL+VDDE L +L+ AL YEGW+V A G A+ ++ PDV+VLDI Sbjct 9 LTRADGSPLRVLVVDDEQMLADLLASALRYEGWEVTTAGTGIAAVRSAQEIDPDVIVLDI 68 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARL Sbjct 69 MLPDFDGLEVMRRVRGHRPNVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVARL 128 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS E L VGDL +D S EV R I L++TEFELLR+LMRNPRR L Sbjct 129 RALLRRSGASEEKQASLLEVGDLRMDEDSHEVWRGEDEIQLTATEFELLRYLMRNPRRVL 188 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ +IV+LYISYLR+KID REPMIHT+RG+GY+L+P Sbjct 189 SKPQILDRVWNYDFGGQANIVELYISYLRRKIDKGREPMIHTMRGVGYVLKP 240 >gi|343522475|ref|ZP_08759441.1| response regulator receiver domain protein [Actinomyces sp. oral taxon 175 str. F0384] gi|343401884|gb|EGV14390.1| response regulator receiver domain protein [Actinomyces sp. oral taxon 175 str. F0384] Length=248 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 145/232 (63%), Positives = 176/232 (76%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + RADGSP+RVL+VDDE L +L+ AL YEGW+V A G A+ ++ PDV+VLDI Sbjct 9 LTRADGSPLRVLVVDDEQMLADLLASALRYEGWEVTTAGTGIAAVRSAQEIDPDVIVLDI 68 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR P LFLTA+D+V DRV GLT+G DDY+TKPFSLEE+VARL Sbjct 69 MLPDFDGLEVMRRVRGHRPNVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEEVVARL 128 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS E L VGDL +D S EV R I L++TEFELLR+LMRNPRR L Sbjct 129 RALLRRSGASEEKPASILEVGDLRMDEDSHEVWRGEDEIQLTATEFELLRYLMRNPRRVL 188 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ +IV+LYISYLR+KID REPMIHT+RG+GY+L+P Sbjct 189 SKPQILDRVWNYDFGGQANIVELYISYLRRKIDKGREPMIHTMRGVGYVLKP 240 >gi|297625540|ref|YP_003687303.1| two component system response regulator [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] gi|32452353|emb|CAD59399.1| putative two-component system regulatory protein [Propionibacterium freudenreichii subsp. shermanii] gi|296921305|emb|CBL55858.1| two component system response regulator [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] Length=242 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 140/232 (61%), Positives = 177/232 (77%), Gaps = 0/232 (0%) Query 24 IHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVLDI 83 + R DG+PIRVL VDDE +LT L+ MA+ YEGW+ A G +A+ PD +VLD+ Sbjct 10 LTRPDGTPIRVLAVDDENSLTELLSMAMRYEGWEPTTAATGSDAVRAARDTNPDAIVLDM 69 Query 84 MLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARL 143 MLPD DGLE++RRVR P +FLTA+D+V DR+ GLT+G DDY+TKPFS+EEL+ARL Sbjct 70 MLPDFDGLEVMRRVRAEQPDVPVIFLTAKDAVNDRIVGLTAGGDDYVTKPFSVEELMARL 129 Query 144 RGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRAL 203 R LLRRS + ++ L VGDL LD S EVTR G I L++TEFELLR+LMRNP+R L Sbjct 130 RSLLRRSGATSKRSESELIVGDLVLDEDSHEVTRGGDEIHLTATEFELLRYLMRNPKRVL 189 Query 204 SRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRP 255 S+ +ILDRVWNYDF G+ ++V+LYISYLRKKID+ REPMIHT+RG GY+L+P Sbjct 190 SKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGREPMIHTMRGAGYVLKP 241 >gi|289428055|ref|ZP_06429759.1| response regulator receiver domain protein [Propionibacterium acnes J165] gi|295131570|ref|YP_003582233.1| transcriptional regulatory protein, C-terminal domain protein [Propionibacterium acnes SK137] gi|335051609|ref|ZP_08544523.1| response regulator MprA [Propionibacterium sp. 409-HC1] 57 more sequence titles Length=243 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 141/238 (60%), Positives = 178/238 (75%), Gaps = 0/238 (0%) Query 20 QLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVL 79 Q R RADGSPIRVL+V+DEP+LT L+ MA+ YEGWDV A+ G A+ + PDV+ Sbjct 6 QPSRFTRADGSPIRVLVVEDEPSLTGLLSMAMRYEGWDVTTANSGAHAVHEAQATRPDVI 65 Query 80 VLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEEL 139 VLD+ L D DGLE++R++R + +FLTA+D+ R+ GLT+G DDY+TKPFSLEE+ Sbjct 66 VLDMRLSDFDGLEVMRQIRINQPTVRAVFLTAKDAASGRIAGLTAGGDDYVTKPFSLEEV 125 Query 140 VARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNP 199 +ARLR LLRRS E D L VGDLTLD SREV R G I L++TEFELLR+ MRNP Sbjct 126 IARLRALLRRSGATEPKPDSMLTVGDLTLDEDSREVRRAGEEIHLTTTEFELLRYFMRNP 185 Query 200 RRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREPMIHTVRGIGYMLRPPE 257 +R LS+ +ILDRVWNYDF G+ ++V+LYISYLRKKID +PMIHT+RG GY+L+P E Sbjct 186 KRVLSKAQILDRVWNYDFRGQANVVELYISYLRKKIDRGHKPMIHTMRGAGYVLKPAE 243 Lambda K H 0.321 0.139 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 380985698940 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40