BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1039c

Length=391
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15840468|ref|NP_335505.1|  PPE family protein [Mycobacterium t...   734    0.0   
gi|289753101|ref|ZP_06512479.1|  PPE family protein [Mycobacteriu...   733    0.0   
gi|339631101|ref|YP_004722743.1|  PPE family protein [Mycobacteri...   733    0.0   
gi|253799929|ref|YP_003032930.1|  PPE family protein [Mycobacteri...   733    0.0   
gi|121636969|ref|YP_977192.1|  PPE family protein [Mycobacterium ...   732    0.0   
gi|340626050|ref|YP_004744502.1|  PPE family protein [Mycobacteri...   732    0.0   
gi|344218866|gb|AEM99496.1|  PPE family protein [Mycobacterium tu...   729    0.0   
gi|254550024|ref|ZP_05140471.1|  PPE family protein [Mycobacteriu...   702    0.0   
gi|297730553|ref|ZP_06959671.1|  PPE family protein [Mycobacteriu...   702    0.0   
gi|118619703|ref|YP_908035.1|  PPE family protein [Mycobacterium ...   444    2e-122
gi|183984423|ref|YP_001852714.1|  PPE family protein, PPE15 [Myco...   437    2e-120
gi|15842306|ref|NP_337343.1|  PPE family protein [Mycobacterium t...   367    2e-99 
gi|254232866|ref|ZP_04926193.1|  PPE family protein [Mycobacteriu...   365    8e-99 
gi|340627770|ref|YP_004746222.1|  PPE family protein [Mycobacteri...   364    1e-98 
gi|57117022|ref|YP_177906.1|  PPE family protein [Mycobacterium t...   364    1e-98 
gi|344220596|gb|AEN01227.1|  PPE family protein [Mycobacterium tu...   363    2e-98 
gi|183981963|ref|YP_001850254.1|  PPE family protein, PPE15_1 [My...   363    2e-98 
gi|289553446|ref|ZP_06442656.1|  PPE family protein [Mycobacteriu...   362    6e-98 
gi|31793943|ref|NP_856436.1|  PPE family protein [Mycobacterium b...   361    1e-97 
gi|148823956|ref|YP_001288710.1|  PPE family protein [Mycobacteri...   360    2e-97 
gi|289569019|ref|ZP_06449246.1|  PPE family protein [Mycobacteriu...   337    2e-90 
gi|240173194|ref|ZP_04751852.1|  PPE family protein, PPE15_1 [Myc...   336    4e-90 
gi|167968597|ref|ZP_02550874.1|  PPE family protein [Mycobacteriu...   335    8e-90 
gi|254551827|ref|ZP_05142274.1|  PPE family protein [Mycobacteriu...   332    9e-89 
gi|31793945|ref|NP_856438.1|  PPE family protein [Mycobacterium b...   274    1e-71 
gi|340627772|ref|YP_004746224.1|  PPE family protein [Mycobacteri...   274    2e-71 
gi|13377911|gb|AAK20895.1|  Rv2770c-like protein [Mycobacterium m...   274    2e-71 
gi|289746573|ref|ZP_06505951.1|  PPE family protein [Mycobacteriu...   273    3e-71 
gi|57117024|ref|YP_177677.1|  PPE family protein [Mycobacterium t...   273    3e-71 
gi|15842308|ref|NP_337345.1|  PPE family protein [Mycobacterium t...   272    6e-71 
gi|289444315|ref|ZP_06434059.1|  PPE family protein [Mycobacteriu...   271    1e-70 
gi|308374682|ref|ZP_07436980.2|  LOW QUALITY PROTEIN: PPE family ...   263    3e-68 
gi|183981960|ref|YP_001850251.1|  PPE family protein, PPE44 [Myco...   258    9e-67 
gi|336461476|gb|EGO40346.1|  PPE-repeat containing protein [Mycob...   253    6e-65 
gi|254774062|ref|ZP_05215578.1|  hypothetical protein MaviaA2_052...   253    6e-65 
gi|41407101|ref|NP_959937.1|  hypothetical protein MAP1003c [Myco...   251    1e-64 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   245    8e-63 
gi|118617719|ref|YP_906051.1|  PPE family protein [Mycobacterium ...   245    1e-62 
gi|294994137|ref|ZP_06799828.1|  PPE family protein [Mycobacteriu...   245    1e-62 
gi|118464457|ref|YP_880591.1|  PPE family protein [Mycobacterium ...   244    2e-62 
gi|167968599|ref|ZP_02550876.1|  PPE family protein [Mycobacteriu...   243    3e-62 
gi|212595937|gb|ACJ35536.1|  PPE10 [Mycobacterium avium subsp. av...   243    6e-62 
gi|240170332|ref|ZP_04748991.1|  PPE family protein, PPE15 [Mycob...   242    9e-62 
gi|306777051|ref|ZP_07415388.1|  PPE family protein [Mycobacteriu...   242    1e-61 
gi|41408673|ref|NP_961509.1|  hypothetical protein MAP2575c [Myco...   241    1e-61 
gi|289574372|ref|ZP_06454599.1|  PPE family protein [Mycobacteriu...   232    1e-58 
gi|333989641|ref|YP_004522255.1|  PPE family protein PPE31_1 [Myc...   231    2e-58 
gi|183982689|ref|YP_001850980.1|  PPE family protein [Mycobacteri...   229    5e-58 
gi|240172861|ref|ZP_04751520.1|  PPE family protein, PPE31 [Mycob...   225    8e-57 
gi|31792891|ref|NP_855384.1|  PPE family protein [Mycobacterium b...   224    1e-56 


>gi|15840468|ref|NP_335505.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31792231|ref|NP_854724.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57116813|ref|YP_177778.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 50 more sequence titles
 Length=391

 Score =  734 bits (1895),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 391/391 (100%), Positives = 391/391 (100%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|289753101|ref|ZP_06512479.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289693688|gb|EFD61117.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=391

 Score =  733 bits (1892),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/391 (99%), Positives = 391/391 (100%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            +QSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  SQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|339631101|ref|YP_004722743.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339330457|emb|CCC26122.1| PPE family protein [Mycobacterium africanum GM041182]
Length=391

 Score =  733 bits (1891),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/391 (99%), Positives = 390/391 (99%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFG LPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGTLPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|253799929|ref|YP_003032930.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289555178|ref|ZP_06444388.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|297633568|ref|ZP_06951348.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|253321432|gb|ACT26035.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289439810|gb|EFD22303.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|328459673|gb|AEB05096.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=391

 Score =  733 bits (1891),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/391 (99%), Positives = 390/391 (99%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMV AAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVTAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|121636969|ref|YP_977192.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224989441|ref|YP_002644128.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|121492616|emb|CAL71084.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224772554|dbj|BAH25360.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341600985|emb|CCC63656.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=391

 Score =  732 bits (1890),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/391 (99%), Positives = 390/391 (99%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTT PGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTKPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|340626050|ref|YP_004744502.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004240|emb|CCC43381.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=391

 Score =  732 bits (1889),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/391 (99%), Positives = 390/391 (99%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAK TGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKSTGAYAGPRYGFKPTVMPKQVVV  391


>gi|344218866|gb|AEM99496.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=391

 Score =  729 bits (1883),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/391 (99%), Positives = 389/391 (99%), Gaps = 0/391 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMV AAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVTAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVANIINSA NTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
Sbjct  241  PFVANIINSADNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
            DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
Sbjct  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV
Sbjct  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|254550024|ref|ZP_05140471.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|289744777|ref|ZP_06504155.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|294995228|ref|ZP_06800919.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|298524536|ref|ZP_07011945.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|289685305|gb|EFD52793.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|298494330|gb|EFI29624.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
Length=377

 Score =  702 bits (1813),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 377/377 (100%), Positives = 377/377 (100%), Gaps = 0/377 (0%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA
Sbjct  1    MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM
Sbjct  61   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA
Sbjct  121  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
            VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA
Sbjct  181  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  240

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  314
            AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE
Sbjct  241  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  300

Query  315  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA  374
            ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA
Sbjct  301  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA  360

Query  375  GPRYGFKPTVMPKQVVV  391
            GPRYGFKPTVMPKQVVV
Sbjct  361  GPRYGFKPTVMPKQVVV  377


>gi|297730553|ref|ZP_06959671.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313657882|ref|ZP_07814762.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=377

 Score =  702 bits (1812),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 376/377 (99%), Positives = 376/377 (99%), Gaps = 0/377 (0%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMV AAQPYLA
Sbjct  1    MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVTAAQPYLA  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM
Sbjct  61   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA
Sbjct  121  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
            VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA
Sbjct  181  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  240

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  314
            AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE
Sbjct  241  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  300

Query  315  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA  374
            ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA
Sbjct  301  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYA  360

Query  375  GPRYGFKPTVMPKQVVV  391
            GPRYGFKPTVMPKQVVV
Sbjct  361  GPRYGFKPTVMPKQVVV  377


>gi|118619703|ref|YP_908035.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118571813|gb|ABL06564.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=390

 Score =  444 bits (1141),  Expect = 2e-122, Method: Compositional matrix adjust.
 Identities = 302/393 (77%), Positives = 330/393 (84%), Gaps = 5/393 (1%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAA AAWNGLA ELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAASAAWNGLAVELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAM+AAAQPYLAWLTYT+EAA HAG+QA ASAAAYEAA+AMTVPP VVAANR+LLAAL
Sbjct  61   ASMAMIAAAQPYLAWLTYTSEAAMHAGAQAAASAAAYEAAFAMTVPPPVVAANRSLLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LGINTPAIMATEALYAEMWAQDA AMYGYAAAS  +G LQPLS P QTTNPGGLA
Sbjct  121  VATNFLGINTPAIMATEALYAEMWAQDAGAMYGYAAASSTSGSLQPLSTPQQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAV  AAA+AA        L+S+LPN + GLASP+TS +D+TGL GII DI+  L  
Sbjct  181  AQSAAVSQAAASAAATD-GTTSLLSNLPNTIMGLASPITSAIDATGLGGIIQDIEDFLGI  239

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PFVAN+IN AVNTAAWY  A IPTAIFLANALN+GAPV IA      A   A+AA AGLA
Sbjct  240  PFVANVINGAVNTAAWYTTATIPTAIFLANALNTGAPV-IAAEGAIEAAEGAAAATAGLA  298

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
            ++VTP G+GA+LGEATLVG+L+VP +WS A P T A   AL GSGWTV  EEA PV+G+ 
Sbjct  299  NTVTPTGVGAALGEATLVGKLAVPTSWSNALPKTAATTGALGGSGWTV-PEEAAPVSGVA  357

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
             +PGMA+AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  358  GVPGMAAAAKGAGAYAGPRYGFKPIVMPKQVVV  390


>gi|183984423|ref|YP_001852714.1| PPE family protein, PPE15 [Mycobacterium marinum M]
 gi|183177749|gb|ACC42859.1| PPE family protein, PPE15 [Mycobacterium marinum M]
Length=390

 Score =  437 bits (1124),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 298/393 (76%), Positives = 330/393 (84%), Gaps = 5/393 (1%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAA AAWNGLA ELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAASAAWNGLAVELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAM+AAAQPYLAWLTYT+EAA HAG+QA ASAAAYEAA+AMTVPP VVAANR+LLAAL
Sbjct  61   ASMAMIAAAQPYLAWLTYTSEAAMHAGAQAAASAAAYEAAFAMTVPPPVVAANRSLLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LGINTPAIMATEALYAEMWAQDA AMYGYAAAS  +G LQPLS P QTTNPGGLA
Sbjct  121  VATNFLGINTPAIMATEALYAEMWAQDAGAMYGYAAASSTSGSLQPLSTPQQTTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAV  AAA+AA     +  L+S+LPN + GLASP+TS +D+TGL GII DI+  L  
Sbjct  181  AQSAAVSQAAASAAATD-GITSLLSNLPNTIMGLASPITSAIDATGLGGIIQDIEDFLGI  239

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FVAN+IN  VNTAAWY  A IPTAIFLANAL++GAPV +A      A   A+AA AGLA
Sbjct  240  GFVANVINGGVNTAAWYTTATIPTAIFLANALDTGAPV-VAAEGAIEAAEGAAAATAGLA  298

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
            ++VTP G+GA+LGEATLVG+L+VP +WS+A P T A   AL GSGWTV  EEA PV+G+ 
Sbjct  299  NTVTPTGVGAALGEATLVGKLAVPTSWSSALPETAATTGALGGSGWTV-PEEAAPVSGVA  357

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
             +PGMA+AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  358  GVPGMAAAAKGAGAYAGPRYGFKPIVMPKQVVV  390


>gi|15842306|ref|NP_337343.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13882601|gb|AAK47157.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=462

 Score =  367 bits (942),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 274/398 (69%), Positives = 303/398 (77%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  69   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  128

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  129  ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  188

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  189  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  248

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  249  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  308

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  309  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  365

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  366  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  424

Query  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V  M  M G++ AAK  GAYAGPRYGFKP VMPKQVVV
Sbjct  425  VAAMPGMAGISGAAKXXGAYAGPRYGFKPIVMPKQVVV  462


>gi|254232866|ref|ZP_04926193.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|289754874|ref|ZP_06514252.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|124601925|gb|EAY60935.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|289695461|gb|EFD62890.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|323718615|gb|EGB27779.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=462

 Score =  365 bits (936),  Expect = 8e-99, Method: Compositional matrix adjust.
 Identities = 276/399 (70%), Positives = 304/399 (77%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  69   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  128

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  129  ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  188

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  189  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  248

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  249  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  308

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  309  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  365

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  366  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  424

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  425  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  462


>gi|340627770|ref|YP_004746222.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005960|emb|CCC45127.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=394

 Score =  364 bits (935),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 275/399 (69%), Positives = 303/399 (76%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AA A +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAARAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  297

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  357  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|57117022|ref|YP_177906.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148662610|ref|YP_001284133.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|254365419|ref|ZP_04981464.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 23 more sequence titles
 Length=394

 Score =  364 bits (935),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 276/399 (70%), Positives = 304/399 (77%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  297

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  357  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|344220596|gb|AEN01227.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=394

 Score =  363 bits (933),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 275/399 (69%), Positives = 302/399 (76%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAALEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  297

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGS W V  EEAGP
Sbjct  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAV-PEEAGP  356

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  357  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|183981963|ref|YP_001850254.1| PPE family protein, PPE15_1 [Mycobacterium marinum M]
 gi|183175289|gb|ACC40399.1| PPE family protein, PPE15_1 [Mycobacterium marinum M]
Length=393

 Score =  363 bits (933),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 260/398 (66%), Positives = 305/398 (77%), Gaps = 12/398 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA PMMAA AAWN LA ELGTTAAS+ESV+T+LTTE WMGP
Sbjct  1    MDFGALPPEINSTRMYAGAGATPMMAAAAAWNRLAVELGTTAASFESVVTQLTTEQWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS +M  A QPYLAWLTYTAE+AAHAG+QA ASAAA+EAA+A TVPP  VAANRA LA L
Sbjct  61   ASTSMAVAVQPYLAWLTYTAESAAHAGAQATASAAAFEAAFAATVPPAAVAANRAQLAML  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            V+TN+LG NTPAI ATEA Y EMWAQDALAMYGYAA+S AAG L PL+ P+Q  NP GLA
Sbjct  121  VSTNILGQNTPAIAATEAQYGEMWAQDALAMYGYAASSAAAGTLNPLTTPAQIANPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            +Q+AAV  AAA   V QV + +LI+++P AV GLASP  S++D+TGLS ++ DI ++L T
Sbjct  181  SQAAAVSQAAAATTVEQVGLGNLITNVPGAVMGLASPAASLVDATGLSTLVQDISSVLGT  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            PF+ N IN AVNTAAW+V AAIP ++FL + LN+   +  A   + A    A A AAGL 
Sbjct  241  PFLQNAINGAVNTAAWFVMAAIPNSVFLGHTLNA---IETAGAPVAADLAPALAPAAGLR  297

Query  301  DSVTP-----AGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +V P     AG+ A LG+A  VG+LSVP  WS+AAPA T+G TAL+GSGW V  EE+GP
Sbjct  298  HAVAPLSFGGAGVEAGLGQAAGVGKLSVPVGWSSAAPALTSGTTALDGSGWAV-PEESGP  356

Query  356  VTGMM--PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            +  M   PGMA A KG G +AGPRYGFKPTVMPKQVVV
Sbjct  357  IAAMPGGPGMAVAGKG-GGFAGPRYGFKPTVMPKQVVV  393


>gi|289553446|ref|ZP_06442656.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289438078|gb|EFD20571.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=411

 Score =  362 bits (929),  Expect = 6e-98, Method: Compositional matrix adjust.
 Identities = 275/399 (69%), Positives = 303/399 (76%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  18   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  77

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  78   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  137

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  138  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  197

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  198  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  257

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  258  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  314

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGS W V  EEAGP
Sbjct  315  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAV-PEEAGP  373

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  374  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  411


>gi|31793943|ref|NP_856436.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121638647|ref|YP_978871.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224991139|ref|YP_002645828.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 8 more sequence titles
 Length=394

 Score =  361 bits (927),  Expect = 1e-97, Method: Compositional matrix adjust.
 Identities = 275/399 (69%), Positives = 303/399 (76%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A I  A+FL +A  +  P  +   A      AA+A     A
Sbjct  241  TFVQNAINGAVNTTAWFVMATIRNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  297

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  357  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|148823956|ref|YP_001288710.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253798149|ref|YP_003031150.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289762940|ref|ZP_06522318.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|148722483|gb|ABR07108.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253319652|gb|ACT24255.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289710446|gb|EFD74462.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|328457922|gb|AEB03345.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=394

 Score =  360 bits (925),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 275/399 (69%), Positives = 303/399 (76%), Gaps = 13/399 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV N IN AVNT AW+V A IP A+FL +A  +  P  +   A      AA+A     A
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---A  297

Query  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGS W V  EEAGP
Sbjct  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAV-PEEAGP  356

Query  356  VTGMMPGM---ASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            V   MPGM   + AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  357  VAA-MPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|289569019|ref|ZP_06449246.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289542773|gb|EFD46421.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=198

 Score =  337 bits (865),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 177/177 (100%), Positives = 177/177 (100%), Gaps = 0/177 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPG  177
            VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPG
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPG  177


>gi|240173194|ref|ZP_04751852.1| PPE family protein, PPE15_1 [Mycobacterium kansasii ATCC 12478]
Length=384

 Score =  336 bits (862),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 270/394 (69%), Positives = 304/394 (78%), Gaps = 13/394 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMYAGAGA PMMAA AAW+ LA EL TTAAS ESVIT+LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAAPMMAAAAAWHRLAVELSTTAASVESVITQLTTEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ASM+M AAAQPYLAWLTYTAE+AAHAGSQA ASAAA+EAA+A TVPP  VAANRALLAAL
Sbjct  61   ASMSMAAAAQPYLAWLTYTAESAAHAGSQATASAAAFEAAFAATVPPAEVAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN+LG NTPAI ATEA Y EMWAQDALAMYGYAA+S AAG L PL+ PS+  NP GLA
Sbjct  121  VATNILGQNTPAIAATEAHYGEMWAQDALAMYGYAASSAAAGTLNPLTTPSRIANPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQ+AAVG AAAT    QV +A+LI+++PN V GLASP  SV D+T L GI   ID LL  
Sbjct  181  AQAAAVGQAAATGTAQQVGLANLITNVPNTVMGLASPAASVFDATALGGI---IDDLLGN  237

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALN-SGAPVAIAEGAIEAAEGAASAAAAGL  299
             FV N IN AVNTAAW+V A IP A+FL +AL+  G   A     I  A    +AAA   
Sbjct  238  TFVQNAINGAVNTAAWFVMATIPNAVFLGHALDVEGLSAAQLVPTIAGAAATTNAAAPAG  297

Query  300  ADSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM  359
            A SV      A +G+A+ VG+L+VPA+WS+AAPA  +G TALEGSGW V  EEAGPVT M
Sbjct  298  AGSVL-----AGMGQASAVGKLAVPASWSSAAPALPSGTTALEGSGWAV-PEEAGPVTAM  351

Query  360  M--PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
               PGMA+A+KG G YAGPRYGF+PTVMPKQVVV
Sbjct  352  PGGPGMAAASKG-GGYAGPRYGFRPTVMPKQVVV  384


>gi|167968597|ref|ZP_02550874.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|294994139|ref|ZP_06799830.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|306777049|ref|ZP_07415386.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 19 more sequence titles
 Length=380

 Score =  335 bits (859),  Expect = 8e-90, Method: Compositional matrix adjust.
 Identities = 263/385 (69%), Positives = 291/385 (76%), Gaps = 13/385 (3%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GPASM+MV AAQPYLA
Sbjct  1    MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAALVATNVLG NTPAIM
Sbjct  61   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA Q+AAV  AAA + 
Sbjct  121  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
            V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL   FV N IN AVNT 
Sbjct  181  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  240

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLG-----  309
            AW+V A IP A+FL +A  +  P  +   A      AA+A     A +VTP G+G     
Sbjct  241  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---AHTVTPVGVGGASLT  297

Query  310  ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGM---ASA  366
            ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGPV   MPGM   + A
Sbjct  298  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGPVAA-MPGMAGISGA  355

Query  367  AKGTGAYAGPRYGFKPTVMPKQVVV  391
            AKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  AKGAGAYAGPRYGFKPIVMPKQVVV  380


>gi|254551827|ref|ZP_05142274.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297635377|ref|ZP_06953157.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|297732375|ref|ZP_06961493.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313659707|ref|ZP_07816587.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=380

 Score =  332 bits (850),  Expect = 9e-89, Method: Compositional matrix adjust.
 Identities = 262/385 (69%), Positives = 290/385 (76%), Gaps = 13/385 (3%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GPASM+MV AAQPYLA
Sbjct  1    MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAALVATNVLG NTPAIM
Sbjct  61   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA Q+AAV  AAA + 
Sbjct  121  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
            V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL   FV N IN AVNT 
Sbjct  181  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  240

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLG-----  309
            AW+V A IP A+FL +A  +  P  +   A      AA+A     A +VTP G+G     
Sbjct  241  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGL---AHTVTPVGVGGASLT  297

Query  310  ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGM---ASA  366
            ASLGEA+ VG LSVPA WSTAAPA T+G TALEGS W V  EEAGPV   MPGM   + A
Sbjct  298  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAV-PEEAGPVAA-MPGMAGISGA  355

Query  367  AKGTGAYAGPRYGFKPTVMPKQVVV  391
            AKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  AKGAGAYAGPRYGFKPIVMPKQVVV  380


>gi|31793945|ref|NP_856438.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121638649|ref|YP_978873.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224991141|ref|YP_002645830.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 15 more sequence titles
 Length=382

 Score =  274 bits (701),  Expect = 1e-71, Method: Compositional matrix adjust.
 Identities = 214/390 (55%), Positives = 254/390 (66%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A+  QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  237

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  238  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  295

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  296  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  349

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  350  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|340627772|ref|YP_004746224.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005962|emb|CCC45129.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=382

 Score =  274 bits (700),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 214/390 (55%), Positives = 254/390 (66%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A+  QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVMSFASPVMSAAD-TGLEAVRQFLN--LDV  237

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  238  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVDGAAPGGGAPAAVAHAVAPAGVG--  295

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  296  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  349

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  350  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|13377911|gb|AAK20895.1| Rv2770c-like protein [Mycobacterium microti]
 gi|13936234|gb|AAK40252.1| 2770c [Mycobacterium microti]
Length=397

 Score =  274 bits (700),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 213/390 (55%), Positives = 254/390 (66%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  16   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  75

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  76   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  135

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  136  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  195

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A+  QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  196  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  252

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  253  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  310

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  311  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  364

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  365  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  394


>gi|289746573|ref|ZP_06505951.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289687101|gb|EFD54589.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=402

 Score =  273 bits (699),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 213/390 (55%), Positives = 254/390 (66%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  21   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  80

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  81   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  140

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  141  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  200

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A+  QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  201  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  257

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  258  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  315

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  316  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  369

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  370  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  399


>gi|57117024|ref|YP_177677.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148662612|ref|YP_001284135.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148823958|ref|YP_001288712.1| PPE family protein [Mycobacterium tuberculosis F11]
 8 more sequence titles
 Length=382

 Score =  273 bits (698),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 214/390 (55%), Positives = 253/390 (65%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A   QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  181  HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  237

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  238  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  295

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  296  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  349

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  350  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|15842308|ref|NP_337345.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|253798147|ref|YP_003031148.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254232868|ref|ZP_04926195.1| PPE family protein [Mycobacterium tuberculosis C]
 10 more sequence titles
 Length=402

 Score =  272 bits (696),  Expect = 6e-71, Method: Compositional matrix adjust.
 Identities = 213/390 (55%), Positives = 253/390 (65%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGP
Sbjct  21   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  80

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  81   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  140

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  141  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  200

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A   QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  201  HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  257

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  258  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  315

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  316  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  369

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  370  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  399


>gi|289444315|ref|ZP_06434059.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289570949|ref|ZP_06451176.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289751427|ref|ZP_06510805.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289754876|ref|ZP_06514254.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289417234|gb|EFD14474.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289544703|gb|EFD48351.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289692014|gb|EFD59443.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289695463|gb|EFD62892.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=382

 Score =  271 bits (694),  Expect = 1e-70, Method: Compositional matrix adjust.
 Identities = 213/390 (55%), Positives = 253/390 (65%), Gaps = 13/390 (3%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WM P
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMVP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
             ATN+LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAVG A A+A+  QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDV  237

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
            P         +   A +  AAI     LA+A+ +    A   GA  A   A + A  G  
Sbjct  238  PLFVESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG--  295

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM-  359
                   L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M 
Sbjct  296  ----GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMP  349

Query  360  -MPGMASAAKGTGAYAGPRYGFKPTVMPKQ  388
              PGM  AA   GA +GPRYG KP VMPK 
Sbjct  350  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|308374682|ref|ZP_07436980.2| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
SUMu006]
 gi|308341059|gb|EFP29910.1| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
SUMu006]
Length=378

 Score =  263 bits (673),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 210/386 (55%), Positives = 249/386 (65%), Gaps = 13/386 (3%)

Query  5    ALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMA  64
            ALPPE+NSARMY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGPAS++
Sbjct  1    ALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLS  60

Query  65   MVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATN  124
            M AA QPYL WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L ATN
Sbjct  61   MAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATN  120

Query  125  VLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSA  184
            +LG N  AI ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA Q+A
Sbjct  121  ILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAA  180

Query  185  AVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVA  244
            AVG A A+A   QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  P   
Sbjct  181  AVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDVPLFV  237

Query  245  NIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVT  304
                  +   A +  AAI     LA+A+ +    A   GA  A   A + A  G      
Sbjct  238  ESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG------  291

Query  305  PAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPG  362
               L A LG A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M   PG
Sbjct  292  GTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMPPAPG  349

Query  363  MASAAKGTGAYAGPRYGFKPTVMPKQ  388
            M  AA   GA +GPRYG KP VMPK 
Sbjct  350  MVVAANSVGADSGPRYGVKPIVMPKH  375


>gi|183981960|ref|YP_001850251.1| PPE family protein, PPE44 [Mycobacterium marinum M]
 gi|183175286|gb|ACC40396.1| PPE family protein, PPE44 [Mycobacterium marinum M]
Length=377

 Score =  258 bits (660),  Expect = 9e-67, Method: Compositional matrix adjust.
 Identities = 205/391 (53%), Positives = 258/391 (66%), Gaps = 18/391 (4%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DFGALPPEINSARMY GAGA P++ A AAWN +A EL T A++ ESVITRL+++ W+G 
Sbjct  5    VDFGALPPEINSARMYFGAGAAPLLGAAAAWNDIAVELSTAASAIESVITRLSSDQWLGT  64

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AAAQP LAWL+YTAE++A A +QA AS AA+E A+AMTVPP  VAANRA LA L
Sbjct  65   ASLSMAAAAQPLLAWLSYTAESSALAAAQAAASVAAFETAFAMTVPPAEVAANRARLAEL  124

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +ATN+ G N PAI ATEA Y EMWAQDA AMYGYAA+   A  L PL+ PS+TTNPGG+A
Sbjct  125  MATNIFGQNVPAIAATEARYGEMWAQDASAMYGYAASCAGAVRLNPLTRPSETTNPGGIA  184

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
             Q+AAV  AAA+ +V Q    +LIS++ +AV  L++PVTS    T L   I DI  L   
Sbjct  185  RQAAAVSHAAASVSVQQAGFENLISTVSDAVMSLSAPVTSSPHVTSLGAFIEDIIFLDIP  244

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV +  +    TA +   A +  A  L   L + A  A +          A+AA + LA
Sbjct  245  RFVESAFHGLGATADY---ATMIAANLL--TLQTSANTATS----AGGVAPAAAAGSALA  295

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
             +VT AG    +G+A+ VG LSVP  W+TAAPA T GA + +G+GW V  E+     GM+
Sbjct  296  QTVTSAG----VGDASSVGALSVPVGWTTAAPAATGGAAS-DGTGWAVPDEDVPSPAGMV  350

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
             G      G GA  GPRYG KP VMPK+V+V
Sbjct  351  AG----TNGAGARPGPRYGVKPRVMPKKVLV  377


>gi|336461476|gb|EGO40346.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=690

 Score =  253 bits (645),  Expect = 6e-65, Method: Compositional matrix adjust.
 Identities = 205/398 (52%), Positives = 257/398 (65%), Gaps = 25/398 (6%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DF A+PPEI SA MYAGAG+GP+MAA  A+  L+AE+ +TA+ +ES+I+ LTTE W G 
Sbjct  311  LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  370

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
             S A  AAAQP +++LT TA A   A +QA ASAAAYEAA+A TVPP V+AANR+LLA L
Sbjct  371  GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  430

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LG+N+ AI ATEA YAEMW QDA  M  Y AAS AAG+LQP++P + TTNPG  A
Sbjct  431  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTNPGAAA  490

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            A      +  AT +  Q +  DL               +S++ S    G++  ID LL T
Sbjct  491  AVDNGAVAFDATNSTAQTAGLDL---------------SSLITSPPTDGLLQSIDDLLGT  535

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNS--GAPVAIAEGAIEAAEGAASAAAAG  298
            P   N  N A+NTAAW+V A IP A+ L   L +    P ++ +    AA  A +     
Sbjct  536  PSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTVPAIPFSLTDSVAPAAGAAITPGM--  593

Query  299  LADSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATA--LEGSGWTVAAEEAGPV  356
            +  SVT AG  A++GEA+ VG LSVPA+WS AAPAT+  ++A  LEGSGWTVA+ EA PV
Sbjct  594  MVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSGWTVAS-EAEPV  652

Query  357  TGMMPGMASAAKGTGAY---AGPRYGFKPTVMPKQVVV  391
            T M     +AA   GA    +GPRYGFKP VMPKQVVV
Sbjct  653  TAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  690


>gi|254774062|ref|ZP_05215578.1| hypothetical protein MaviaA2_05233 [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|212595906|gb|ACJ35532.1| PPE6 [Mycobacterium avium subsp. avium]
 gi|212595970|gb|ACJ35540.1| PPE15 [Mycobacterium avium subsp. avium]
Length=382

 Score =  253 bits (645),  Expect = 6e-65, Method: Compositional matrix adjust.
 Identities = 205/398 (52%), Positives = 257/398 (65%), Gaps = 25/398 (6%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DF A+PPEI SA MYAGAG+GP+MAA  A+  L+AE+ +TA+ +ES+I+ LTTE W G 
Sbjct  3    LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  62

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
             S A  AAAQP +++LT TA A   A +QA ASAAAYEAA+A TVPP V+AANR+LLA L
Sbjct  63   GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  122

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LG+N+ AI ATEA YAEMW QDA  M  Y AAS AAG+LQP++P + TTNPG  A
Sbjct  123  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTNPGAAA  182

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            A      +  AT +  Q +  DL               +S++ S    G++  ID LL T
Sbjct  183  AVDNGAVAFDATNSTAQTAGLDL---------------SSLITSPPTDGLLQSIDDLLGT  227

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNS--GAPVAIAEGAIEAAEGAASAAAAG  298
            P   N  N A+NTAAW+V A IP A+ L   L +    P ++ +    AA  A +     
Sbjct  228  PSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTVPAIPFSLTDSVAPAAGAAITPGM--  285

Query  299  LADSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATA--LEGSGWTVAAEEAGPV  356
            +  SVT AG  A++GEA+ VG LSVPA+WS AAPAT+  ++A  LEGSGWTVA+ EA PV
Sbjct  286  MVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSGWTVAS-EAEPV  344

Query  357  TGMMPGMASAAKGTGAY---AGPRYGFKPTVMPKQVVV  391
            T M     +AA   GA    +GPRYGFKP VMPKQVVV
Sbjct  345  TAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  382


>gi|41407101|ref|NP_959937.1| hypothetical protein MAP1003c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395452|gb|AAS03320.1| PE [Mycobacterium avium subsp. paratuberculosis K-10]
Length=696

 Score =  251 bits (642),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 205/398 (52%), Positives = 257/398 (65%), Gaps = 25/398 (6%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DF A+PPEI SA MYAGAG+GP+MAA  A+  L+AE+ +TA+ +ES+I+ LTTE W G 
Sbjct  317  LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  376

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
             S A  AAAQP +++LT TA A   A +QA ASAAAYEAA+A TVPP V+AANR+LLA L
Sbjct  377  GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  436

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LG+N+ AI ATEA YAEMW QDA  M  Y AAS AAG+LQP++P + TTNPG  A
Sbjct  437  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTNPGAAA  496

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            A      +  AT +  Q +  DL               +S++ S    G++  ID LL T
Sbjct  497  AVDNGAVAFDATNSTAQTAGLDL---------------SSLITSPPTDGLLQSIDDLLGT  541

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNS--GAPVAIAEGAIEAAEGAASAAAAG  298
            P   N  N A+NTAAW+V A IP A+ L   L +    P ++ +    AA  A +     
Sbjct  542  PSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTVPAIPFSLTDSVAPAAGAAITPGM--  599

Query  299  LADSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATA--LEGSGWTVAAEEAGPV  356
            +  SVT AG  A++GEA+ VG LSVPA+WS AAPAT+  ++A  LEGSGWTVA+ EA PV
Sbjct  600  MVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSGWTVAS-EAEPV  658

Query  357  TGMMPGMASAAKGTGAY---AGPRYGFKPTVMPKQVVV  391
            T M     +AA   GA    +GPRYGFKP VMPKQVVV
Sbjct  659  TAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  696


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  245 bits (626),  Expect = 8e-63, Method: Compositional matrix adjust.
 Identities = 191/417 (46%), Positives = 246/417 (59%), Gaps = 30/417 (7%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDF ALPPEINS RMY+G G+ PM+AA  AW+GLAAEL +TAA+YE+VI  LT + W+GP
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS +M AA  PYLAW+  T   A     QA A+A A+EAA+AMTVPP  VAANR  L  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN+LG NTPAI ATEA Y EMWAQDA AMYGYA  S AA  L   + P+QTT+P GLA
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  181  AQSAAVGSAAATAAVN--QVSVADLISSLPNAVSGLASP-VTSVLDSTGLSGIIA----D  233
            +QSAAV  A  +   N  Q  +  L+S++P ++ GLASP   S +D+   SG++A     
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  234  IDALLATPFVANIINSAVN--TAAWYVN-AAIPTAIFLA----NALNSGA-------PVA  279
            +D     P+   + +S VN   +A YV+ A +  AI+ A    NA+  GA       P+ 
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADINAVALGAQESAAVPPMG  300

Query  280  IAEGA---IEAAEGAASAAAAGLAD----SVTPAGLGASLGEATLVGRLSVPAAWSTAAP  332
              EG    I AA  A+  +   L +    ++   G+ A + +A LVGR+SVP +W  A  
Sbjct  301  SGEGNPSWIPAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRMSVPQSWGVATA  360

Query  333  ATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPK  387
                   A  G GWT  A       GM  +PGM +   G      PRYGF+PT+M +
Sbjct  361  VANHAGAAAPGGGWTSTAVVPEAAVGMPGIPGMPAGIYGHNLGNAPRYGFRPTIMGR  417


>gi|118617719|ref|YP_906051.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118569829|gb|ABL04580.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=373

 Score =  245 bits (625),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 206/391 (53%), Positives = 259/391 (67%), Gaps = 18/391 (4%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPEINSARMY GAGA P++ A AAWN +A EL T A++ ESVITRL+++ W+G 
Sbjct  1    MDFGALPPEINSARMYFGAGAAPLLGAAAAWNDIAVELSTAASAIESVITRLSSDQWLGT  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AAAQP LAWL+YTAE++A A +QA AS AA+E A+AMTVPP  VAANRA LAAL
Sbjct  61   ASLSMAAAAQPLLAWLSYTAESSALAAAQAAASVAAFETAFAMTVPPAEVAANRARLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +ATN+ G N PAI ATEA Y EMWAQDA AMYGYAA+   A  L PL+ PS+TTNPGG+A
Sbjct  121  MATNIFGQNVPAIAATEARYGEMWAQDASAMYGYAASCAGAVRLNPLTRPSETTNPGGIA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            +Q+ AV  AAA+ +V Q    +LIS++ +AV+ L+ PVTS    T L   I DI  L   
Sbjct  181  SQAVAVSHAAASVSVQQAGFENLISTVSDAVTSLSGPVTSSPHVTSLGAFIEDIIFLDIP  240

Query  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300
             FV +  +    TA +   A +  A  L   L + A  A +          A+AA + LA
Sbjct  241  RFVESAFHGLGATADY---ATMIAANLL--TLQTSANTATS----AGGVAPAAAAGSALA  291

Query  301  DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM  360
             +VT AG    +G+A+ VG LSVP  W+TAAPA T GA + +G+GW V  E+     GM+
Sbjct  292  QTVTSAG----VGDASSVGALSVPVGWTTAAPAATGGAAS-DGTGWAVPDEDVPSPAGMV  346

Query  361  PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
             G      G GA  GPRYG KP VMPK+V+V
Sbjct  347  AG----TNGAGARPGPRYGVKPRVMPKKVLV  373


>gi|294994137|ref|ZP_06799828.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|339295620|gb|AEJ47731.1| Rv2770c-like protein [Mycobacterium tuberculosis CCDC5079]
 gi|339299237|gb|AEJ51347.1| Rv2770c-like protein [Mycobacterium tuberculosis CCDC5180]
Length=368

 Score =  245 bits (625),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 201/376 (54%), Positives = 240/376 (64%), Gaps = 13/376 (3%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGPAS++M AA QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLV  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L ATN+LG N  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA Q+AAVG A A+A+
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAS  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
              QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  P         +   
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDVPLFVESAFHGLGGV  237

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  314
            A +  AAI     LA+A+ +    A   GA  A   A + A  G         L A LG 
Sbjct  238  ADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG------GTALTADLGN  291

Query  315  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAAKGTGA  372
            A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M   PGM  AA   GA
Sbjct  292  ASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMPPAPGMVVAANSVGA  349

Query  373  YAGPRYGFKPTVMPKQ  388
             +GPRYG KP VMPK 
Sbjct  350  DSGPRYGVKPIVMPKH  365


>gi|118464457|ref|YP_880591.1| PPE family protein [Mycobacterium avium 104]
 gi|118165744|gb|ABK66641.1| ppe family protein [Mycobacterium avium 104]
Length=383

 Score =  244 bits (623),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 205/403 (51%), Positives = 245/403 (61%), Gaps = 34/403 (8%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
             DFGALPPE+NS RMY GAGA PMMAA AA++ LA EL TTAA+ +S I  LT E WMGP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ++ AMV A QPY+ W+  TA     A +QAMASAAAYE A+AMTVPP +VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +A+NVLG N  AI ATEA Y EMWAQDA AMYGYAA+S  AG L PL+ P+ T  PGGL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  AQSAAVGSAAATAAVNQVS-VADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLA  239
            AQ+AAV  A AT+A  Q S +   ++++PN V  LA+P     D  GLS     +D LL 
Sbjct  183  AQAAAVSGATATSA--QTSGLQGTVANVPNVVRTLAAPA----DPPGLSA----LDNLLG  232

Query  240  TPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGL  299
             P V N+ N+  N  +W V   I + I   + L++    A A G      GA    A   
Sbjct  233  NPVVNNVGNAGFNVVSWNVFNTIVSNILYNHTLDT----AAAAGVAGEVGGAVGGGALVG  288

Query  300  ADSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAP---ATTAGATALEGSGWTVAAE  351
            A +   AG+G     AS+G A  VG LS PA WS   P   ATT GAT      W   AE
Sbjct  289  AAAPATAGVGAAPVLASMGSAATVGELSTPATWSAPTPEPAATTVGATE-----WASPAE  343

Query  352  EAGPVTGM---MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            E  P T     MP +ASA +G G   GPRYG KP VMP ++ V
Sbjct  344  E--PHTAWATGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|167968599|ref|ZP_02550876.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|254551829|ref|ZP_05142276.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297635379|ref|ZP_06953159.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 14 more sequence titles
 Length=368

 Score =  243 bits (621),  Expect = 3e-62, Method: Compositional matrix adjust.
 Identities = 201/376 (54%), Positives = 239/376 (64%), Gaps = 13/376 (3%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGPAS++M AA QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLV  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L ATN+LG N  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA Q+AAVG A A+A 
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAF  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
              QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  P         +   
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDVPLFVESAFHGLGGV  237

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  314
            A +  AAI     LA+A+ +    A   GA  A   A + A  G         L A LG 
Sbjct  238  ADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG------GTALTADLGN  291

Query  315  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAAKGTGA  372
            A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M   PGM  AA   GA
Sbjct  292  ASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMPPAPGMVVAANSVGA  349

Query  373  YAGPRYGFKPTVMPKQ  388
             +GPRYG KP VMPK 
Sbjct  350  DSGPRYGVKPIVMPKH  365


>gi|212595937|gb|ACJ35536.1| PPE10 [Mycobacterium avium subsp. avium]
Length=383

 Score =  243 bits (619),  Expect = 6e-62, Method: Compositional matrix adjust.
 Identities = 204/403 (51%), Positives = 245/403 (61%), Gaps = 34/403 (8%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
             DFGALPPE+NS RMY GAGA PMMAA AA++ LA EL TTAA+ +S I  LT E WMGP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ++ AMV A QPY+ W+  TA     A +QAMASAAAYE A+AMTVPP +VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +A+NVLG N  AI ATEA Y EMWAQDA AMYGYAA+S  AG L PL+ P+ T  PGGL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  AQSAAVGSAAATAAVNQVS-VADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLA  239
            AQ+AAV  A AT+A  Q S +   ++++PN V  LA+P     D  GLS     +D LL 
Sbjct  183  AQAAAVSGATATSA--QTSGLQGTVANVPNVVRTLAAPA----DPPGLSA----LDNLLG  232

Query  240  TPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGL  299
             P V N+ N+  +  +W V   I + I   + L++    A A G      GA    A   
Sbjct  233  NPVVNNVGNAGFDVVSWNVFNTIVSNILYNHTLDT----AAAAGVAGEVGGAVGGGALVG  288

Query  300  ADSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAP---ATTAGATALEGSGWTVAAE  351
            A +   AG+G     AS+G A  VG LS PA WS   P   ATT GAT      W   AE
Sbjct  289  AAAPATAGVGAAPVLASMGSAATVGELSTPATWSAPTPEPAATTVGATE-----WASPAE  343

Query  352  EAGPVTGM---MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            E  P T     MP +ASA +G G   GPRYG KP VMP ++ V
Sbjct  344  E--PHTAWATGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|240170332|ref|ZP_04748991.1| PPE family protein, PPE15 [Mycobacterium kansasii ATCC 12478]
Length=261

 Score =  242 bits (617),  Expect = 9e-62, Method: Compositional matrix adjust.
 Identities = 192/261 (74%), Positives = 220/261 (85%), Gaps = 0/261 (0%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDF ALPPEINS RMYAGAGAGP++AA AAWNGLA EL TTAAS ES++T LT E W+GP
Sbjct  1    MDFAALPPEINSGRMYAGAGAGPLLAAAAAWNGLALELNTTAASIESIVTLLTGEQWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AAAQPY+AWLTYT  +A HAG+QAMASAAAYEAA+A TVPP ++AANRALLAAL
Sbjct  61   ASLSMAAAAQPYIAWLTYTGASAEHAGAQAMASAAAYEAAFAATVPPPIIAANRALLAAL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LGINTPAIMATEA Y EMWAQDA+AMY YAA+S  +G L PL+ PSQ+TNPGGLA
Sbjct  121  VATNFLGINTPAIMATEAHYMEMWAQDAMAMYAYAASSANSGTLNPLTTPSQSTNPGGLA  180

Query  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240
            AQSAAVG AAA A VNQV ++ LI+ LPNAV  LASP+TSV D+TGL+GI+  ID LLA 
Sbjct  181  AQSAAVGQAAAAATVNQVGLSSLITDLPNAVMSLASPITSVADATGLTGIMQSIDDLLAI  240

Query  241  PFVANIINSAVNTAAWYVNAA  261
            P VANI+N  +NTAAW+V AA
Sbjct  241  PMVANILNGGINTAAWFVMAA  261


>gi|306777051|ref|ZP_07415388.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|306973166|ref|ZP_07485827.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|307080875|ref|ZP_07490045.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308214561|gb|EFO73960.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308357429|gb|EFP46280.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308361380|gb|EFP50231.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=368

 Score =  242 bits (617),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 200/376 (54%), Positives = 238/376 (64%), Gaps = 13/376 (3%)

Query  15   MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  74
            MY GAGA  ++AA AAWNG+A E+ T A+S  SVITRL+TE WMGPAS++M A  QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAATVQPYLV  60

Query  75   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  134
            WLT TAE++A A +QAMASAAA+E A+A+TVPP  V ANRALLA L ATN+LG N  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  194
            ATEA Y EMWAQDA AMYGYAAAS  A  L PL+ PS  TNP GLA Q+AAVG A A+A 
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAF  180

Query  195  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  254
              QV ++ LIS + +AV   ASPV S  D TGL  +   ++  L  P         +   
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAAD-TGLEAVRQFLN--LDVPLFVESAFHGLGGV  237

Query  255  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGE  314
            A +  AAI     LA+A+ +    A   GA  A   A + A  G         L A LG 
Sbjct  238  ADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVG------GTALTADLGN  291

Query  315  ATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAAKGTGA  372
            A++VGRLSVPA+WSTAA   TA   AL+G+GW V  EE GP+  M   PGM  AA   GA
Sbjct  292  ASVVGRLSVPASWSTAA-PATAAGAALDGTGWAV-PEEDGPIAVMPPAPGMVVAANSVGA  349

Query  373  YAGPRYGFKPTVMPKQ  388
             +GPRYG KP VMPK 
Sbjct  350  DSGPRYGVKPIVMPKH  365


>gi|41408673|ref|NP_961509.1| hypothetical protein MAP2575c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397031|gb|AAS04892.1| hypothetical protein MAP_2575c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458621|gb|EGO37586.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=383

 Score =  241 bits (616),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 203/403 (51%), Positives = 245/403 (61%), Gaps = 34/403 (8%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
             DFGALPPE+NS RMY GAGA PMMAA AA++ LA EL TTAA+ +S I  LT E WMGP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            ++ AMV A QPY+ W+  TA     A +QAMASAAAYE A+AMTVPP +VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +A+NVLG N  AI ATEA Y EMWAQDA AMYGYAA+S  AG L PL+ P+ T  PGGL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  AQSAAVGSAAATAAVNQVS-VADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLA  239
            AQ+AAV  A AT+A  Q S +   ++++PN V  LA+P     D  GL+     +D LL 
Sbjct  183  AQAAAVSGATATSA--QTSGLQGTVANVPNVVRTLAAPA----DPPGLTA----LDNLLG  232

Query  240  TPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGL  299
             P V N+ N+  +  +W V   I + I   + L++    A A G      GA    A   
Sbjct  233  NPVVNNVGNAGFDVVSWNVFNTIVSNILYNHTLDT----AAAAGVAGEVGGAVGGGALVG  288

Query  300  ADSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAP---ATTAGATALEGSGWTVAAE  351
            A +   AG+G     AS+G A  VG LS PA WS   P   ATT GAT      W   AE
Sbjct  289  AAAPATAGVGAAPVLASMGSAATVGELSTPATWSAPTPEPAATTVGATE-----WASPAE  343

Query  352  EAGPVTGM---MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391
            E  P T     MP +ASA +G G   GPRYG KP VMP ++ V
Sbjct  344  E--PHTAWATGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|289574372|ref|ZP_06454599.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538803|gb|EFD43381.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=384

 Score =  232 bits (591),  Expect = 1e-58, Method: Compositional matrix adjust.
 Identities = 177/405 (44%), Positives = 226/405 (56%), Gaps = 44/405 (10%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NS RMY G G+ PM+AA +AWNGLAAEL   A  YE VIT L TE W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS  MV A  PY+AW+  TA  A  A SQA A+AAAYE A+A  VPP ++AANRA L +L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            V  NV G NT +I ATEA YAEMWAQDA+AMYGYA +S  A  + P +PP  TT+P   A
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  AQSAAVGSAAATAA-VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLA  239
             Q +AV  AA T+A   Q ++A+LI+ LPN + GL SP++S L +    G +        
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWL--------  232

Query  240  TPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAP---VAIAEGAIEA--------A  288
                            W++N  +P +    N +  G P   + I    I +        +
Sbjct  233  ---------------EWFINWYLPISQLFYNTV--GLPYFAIGIGNSLITSWRALGWIGS  275

Query  289  EGAASAAAAGLADSVTPAGLG---ASLGEATLVGRLSVPAAWSTAAP--ATTAGATALEG  343
             G  S  AA    S    G G   A LG A  +G+LSVP  W+ A+P  A T G+ +   
Sbjct  276  RGRRSCRAA-RRPSARVCGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL  334

Query  344  SGWTVAAEEAGPVTGMMPGMA-SAAKGTGAYAGPRYGFKPTVMPK  387
                V   EAG    ++ GM  + +      AGPRYGF+ TVM +
Sbjct  335  VSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSR  379


>gi|333989641|ref|YP_004522255.1| PPE family protein PPE31_1 [Mycobacterium sp. JDM601]
 gi|333485609|gb|AEF35001.1| PPE family protein PPE31_1 [Mycobacterium sp. JDM601]
Length=424

 Score =  231 bits (588),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 190/423 (45%), Positives = 242/423 (58%), Gaps = 35/423 (8%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +D+  LPPE+NSAR+YAG G+ PMMA  +AW GLAAE+ +   SYE+ +T+L  E+WMGP
Sbjct  2    IDYATLPPEVNSARLYAGPGSTPMMAVASAWRGLAAEISSALTSYETTLTQLVDEAWMGP  61

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS++M AA +PYLAWLT T   A    S+A A+AAA+EAA+  T PP V+AANRA    L
Sbjct  62   ASVSMTAATKPYLAWLTDTLAKAEDTASRATAAAAAFEAAHGATPPPAVIAANRAQQKQL  121

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATNV+G N+ AIMA++A Y EMWAQ A  MY YAA+S  A  + P S P+QTTNP G A
Sbjct  122  VATNVVGQNSAAIMASDAQYLEMWAQAANVMYSYAASSATATQVTPFSEPNQTTNPDGTA  181

Query  181  AQSAAVGS---AAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGII------  231
             Q+AAVG     AA         A LISSLPNA+  L SP  + L    L+G++      
Sbjct  182  NQAAAVGQANATAAGNTAQNAQTAQLISSLPNALQTLTSPAPTDLPPPTLAGLVEAFFRN  241

Query  232  ADID---ALLATPFVANIINSAVNTAAWYVNAA-IP--TAIFLANALNS-----------  274
            A I+   +LL  P    +  S V T+A +  A+ IP  T  F  +  N+           
Sbjct  242  ASINGVVSLLTYPLNGGM--SFVGTSAAFTPASLIPTMTTFFSGSGFNALGGGSAGAGIG  299

Query  275  -----GAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLGASLGEATLVGRLS-VPAAWS  328
                 G P++          GAASAAA     S T   + A +G+ATLVG LS  PA  +
Sbjct  300  ALLAPGGPLSSLGALGGGTAGAASAAAGAFTASATTPAISAGVGQATLVGELSAPPAWAA  359

Query  329  TAAPATTAGATALEGSGWTVAAEEAGPVTGMMPGMASAAKGTGAYAG-PRYGFKPTVMPK  387
             A   T A   AL+ S W+ A EE   +  M  GM   A  +G   G PRYGFKPTVM +
Sbjct  360  AAPAGTAATGDALQASSWSAAPEEIESMAAMPGGMPLGADRSGFGLGTPRYGFKPTVMAR  419

Query  388  QVV  390
             VV
Sbjct  420  PVV  422


>gi|183982689|ref|YP_001850980.1| PPE family protein [Mycobacterium marinum M]
 gi|183176015|gb|ACC41125.1| PPE family protein [Mycobacterium marinum M]
Length=409

 Score =  229 bits (584),  Expect = 5e-58, Method: Compositional matrix adjust.
 Identities = 199/411 (49%), Positives = 254/411 (62%), Gaps = 32/411 (7%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NS RMY+G G+ PM+AA AAW+ ++AE+  TAA+YESV++ L ++ W+GP
Sbjct  6    MDFGALPPEVNSLRMYSGPGSAPMLAAMAAWDDVSAEMLLTAAAYESVLSALLSDGWLGP  65

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS AM AAA PY+ WL+ T   AA    QA A+AAA+EAA+AMTVPP VVAANR  L  L
Sbjct  66   ASAAMAAAAAPYVTWLSATGLQAAQTAGQAAAAAAAFEAAFAMTVPPSVVAANRVQLLTL  125

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            VATN LGINTPAI ATEA YAEMWAQDA AMYGYAA S  A  L+P S P+ T +  GLA
Sbjct  126  VATNFLGINTPAIAATEAEYAEMWAQDATAMYGYAAGSAVASTLEPFSEPAHTASRSGLA  185

Query  181  AQSAAVGSAAATA--AVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALL  238
             Q+AAV  AA+TA   + Q  +  L+S++P ++ GLA+P  + LD+   SG++ADI   L
Sbjct  186  GQTAAVAQAASTAMGGLTQTELPQLMSAVPASLQGLAAPAAAPLDTIAGSGLLADILNFL  245

Query  239  A-----------TPFVANIINSAVNTAAWYVNAAIPTAIFLANALN-SGAPVAIAEGAIE  286
                           +AN + SA  TA   V  A+ +A+   NAL   G P     G   
Sbjct  246  DGNDGNAFGIFLNSSLANGVISAGYTAPGIVVPAVTSAMADVNALALDGLP-----GIAL  300

Query  287  AAEGAASAAAAGLADSVTPAGLG---ASLGEATLVGRLSVPAAWSTAAPATTAGATALEG  343
               G+ S  A     +V  +GLG   A   +AT+VGRLSVP +W+     T   ATAL G
Sbjct  301  PITGSDSGDAVWTRMTVPQSGLGGVAAGTNQATMVGRLSVPPSWAGTTEVTDHVATALPG  360

Query  344  SGWTVAAEEAGPVTGMMPGMASAAKGTGAYA-----GPRYGFKPTVMPKQV  389
            +G T  A EA   +  MPG+       GAYA     GPRYGF+ T+MP+ +
Sbjct  361  AG-TATAPEA---SAAMPGV-PGVPAPGAYARSYGTGPRYGFRLTIMPRPL  406


>gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478]
Length=401

 Score =  225 bits (574),  Expect = 8e-57, Method: Compositional matrix adjust.
 Identities = 194/402 (49%), Positives = 242/402 (61%), Gaps = 25/402 (6%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            +DF  LPPEINSARMY+G G+GPM+AA +AW  LAAEL  TA SY SV+  LT E W GP
Sbjct  5    LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP  64

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS +M AAA PY+AWL  TA  A     QA A+A AYEAA+  TVPP V+AANRA L AL
Sbjct  65   ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL  124

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            +ATN+LG NTPAI ATEA Y EMWAQDA+AMYGYA +S AA  L P   P Q TNP GLA
Sbjct  125  IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA  184

Query  181  AQSAAVGSAAATAAVNQVS-VADLISSLPNAVSGLASPVTSVLDSTGLSGIIADI-----  234
            AQ+AAV  A+A +A NQ S ++ LIS +P+A+ GL+ P     +ST    +I D+     
Sbjct  185  AQAAAVTEASANSAGNQSSTLSGLISMVPSALQGLSGP-----NSTSWLQVIWDLLTGSG  239

Query  235  DALLATPF-----VANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAE  289
             A   T +      AN+ N+  +T  +   +    A F+A+ L        A+ A  AA 
Sbjct  240  PAWWQTLWNVWGPNANVWNTITSTGLFVPGSTF--APFMASVLAGAVAADAAQDASAAAA  297

Query  290  GAASAAAAGLADSVTPAG--LGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWT  347
            G  S  AAG   S    G  + A LG A +VG+LSVP AW+ AAP  +   +AL G+   
Sbjct  298  GVGSGLAAGPLASTGSVGSAVSAGLGNAGIVGKLSVPPAWTAAAPLHSPLGSALGGTP-M  356

Query  348  VAAEEAGPVTGMMPGM--ASAAKGTGAYAGPRYGFKPTVMPK  387
            VA   A  V   MPGM   + A      A P+YGF+PT + +
Sbjct  357  VAPPPA--VAAGMPGMPFGNMAGQPFGRAVPQYGFRPTFVAR  396


>gi|31792891|ref|NP_855384.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|224990087|ref|YP_002644774.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|289443162|ref|ZP_06432906.1| PPE family protein [Mycobacterium tuberculosis T46]
 18 more sequence titles
 Length=385

 Score =  224 bits (572),  Expect = 1e-56, Method: Compositional matrix adjust.
 Identities = 176/405 (44%), Positives = 226/405 (56%), Gaps = 43/405 (10%)

Query  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60
            MDFGALPPE+NS RMY G G+ PM+AA +AWNGLAAEL   A  YE VIT L TE W+GP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120
            AS  MV A  PY+AW+  TA  A  A SQA A+AAAYE A+A  VPP ++AANRA L +L
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180
            V  NV G NT +I ATEA YAEMWAQDA+AMYGYA +S  A  + P +PP  TT+P   A
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  181  AQSAAVGSAAATAA-VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLA  239
             Q +AV  AA T+A   Q ++A+LI+ LPN + GL SP++S L +    G +        
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAAATPGWL--------  232

Query  240  TPFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAP---VAIAEGAIEAAEG------  290
                            W++N  +P +    N +  G P   + I    I +         
Sbjct  233  ---------------EWFINWYLPISQLFYNTV--GLPYFAIGIGNSLITSWRALGWIGP  275

Query  291  -----AASAAAAGLADSVTPAGLGASLGEATLVGRLSVPAAWSTAAP--ATTAGATALEG  343
                 AA+A AA  A       + A LG A  +G+LSVP  W+ A+P  A T G+ +   
Sbjct  276  EAAEAAAAAPAAVGAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTVGSASAPL  335

Query  344  SGWTVAAEEAGPVTGMMPGMA-SAAKGTGAYAGPRYGFKPTVMPK  387
                V   EAG    ++ GM  + +      AGPRYGF+ TVM +
Sbjct  336  VSDIVEQPEAGAAGNLLGGMPLAGSGTGTGGAGPRYGFRVTVMSR  380



Lambda     K      H
   0.312    0.122    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 768123887500


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40