BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1077 Length=464 Score E Sequences producing significant alignments: (Bits) Value gi|15840513|ref|NP_335550.1| cysteine synthase/cystathionine bet... 925 0.0 gi|289749609|ref|ZP_06508987.1| cystathionine beta-synthase cbs ... 924 0.0 gi|289744817|ref|ZP_06504195.1| cysteine synthase/cystathionine ... 885 0.0 gi|240170290|ref|ZP_04748949.1| putative cystathionine beta-synt... 847 0.0 gi|183984361|ref|YP_001852652.1| cystathionine beta-synthase CBS... 838 0.0 gi|254820655|ref|ZP_05225656.1| cystathionine beta-synthase [Myc... 834 0.0 gi|342861668|ref|ZP_08718314.1| cystathionine beta-synthase [Myc... 831 0.0 gi|118616093|ref|YP_904425.1| cystathionine beta-synthase CBS [M... 831 0.0 gi|289761215|ref|ZP_06520593.1| cystathionine beta-synthase cbs ... 830 0.0 gi|41407122|ref|NP_959958.1| CysM2 [Mycobacterium avium subsp. p... 827 0.0 gi|296169941|ref|ZP_06851550.1| cystathionine beta-synthase [Myc... 826 0.0 gi|15828289|ref|NP_302552.1| cystathionine [beta]-synthase [Myco... 807 0.0 gi|120405626|ref|YP_955455.1| cystathionine beta-synthase [Mycob... 798 0.0 gi|126436951|ref|YP_001072642.1| cystathionine beta-synthase [My... 796 0.0 gi|108801113|ref|YP_641310.1| cystathionine beta-synthase [Mycob... 795 0.0 gi|145222631|ref|YP_001133309.1| cystathionine beta-synthase [My... 788 0.0 gi|118472959|ref|YP_889516.1| cystathionine beta-synthase [Mycob... 785 0.0 gi|169628288|ref|YP_001701937.1| cystathionine beta-synthase [My... 769 0.0 gi|333989663|ref|YP_004522277.1| cystathionine beta-synthase CBS... 762 0.0 gi|226307753|ref|YP_002767713.1| cystathionine beta-synthase [Rh... 746 0.0 gi|343925073|ref|ZP_08764605.1| cystathionine beta-synthase [Gor... 742 0.0 gi|111022806|ref|YP_705778.1| cystathionine beta-synthase [Rhodo... 739 0.0 gi|54026806|ref|YP_121048.1| putative cystathionine beta-synthas... 739 0.0 gi|226365313|ref|YP_002783096.1| cystathionine beta-synthase [Rh... 739 0.0 gi|262201573|ref|YP_003272781.1| cystathionine beta-synthase [Go... 734 0.0 gi|325676583|ref|ZP_08156261.1| cystathionine beta-synthase [Rho... 734 0.0 gi|312138725|ref|YP_004006061.1| cystathionine beta synthase cys... 732 0.0 gi|296140835|ref|YP_003648078.1| cystathionine beta-synthase [Ts... 726 0.0 gi|326381815|ref|ZP_08203508.1| cystathionine beta-synthase [Gor... 724 0.0 gi|333921104|ref|YP_004494685.1| putative cystathionine beta-syn... 712 0.0 gi|311742687|ref|ZP_07716496.1| cystathionine beta-synthase [Aer... 688 0.0 gi|296394384|ref|YP_003659268.1| cystathionine beta-synthase [Se... 686 0.0 gi|258654542|ref|YP_003203698.1| cystathionine beta-synthase [Na... 672 0.0 gi|332671462|ref|YP_004454470.1| cystathionine beta-synthase [Ce... 662 0.0 gi|317124081|ref|YP_004098193.1| cystathionine beta-synthase [In... 660 0.0 gi|296128782|ref|YP_003636032.1| cystathionine beta-synthase [Ce... 659 0.0 gi|84497854|ref|ZP_00996651.1| putative cystathionine beta-synth... 657 0.0 gi|152965050|ref|YP_001360834.1| cystathionine beta-synthase [Ki... 657 0.0 gi|134097497|ref|YP_001103158.1| cystathionine beta-synthase [Sa... 655 0.0 gi|269957454|ref|YP_003327243.1| cystathionine beta-synthase [Xy... 654 0.0 gi|302530131|ref|ZP_07282473.1| cystathionine beta-synthase [Str... 642 0.0 gi|257057157|ref|YP_003134989.1| cystathionine beta-synthase [Sa... 637 1e-180 gi|300789921|ref|YP_003770212.1| cystathionine beta-synthase [Am... 637 1e-180 gi|148272051|ref|YP_001221612.1| putative cystathionine beta-syn... 633 2e-179 gi|256374849|ref|YP_003098509.1| cystathionine beta-synthase [Ac... 632 4e-179 gi|334337936|ref|YP_004543088.1| cystathionine beta-synthase [Is... 629 3e-178 gi|170780583|ref|YP_001708915.1| putative cystathionine beta-syn... 628 5e-178 gi|330465834|ref|YP_004403577.1| cystathionine beta-synthase [Ve... 623 2e-176 gi|325003215|ref|ZP_08124327.1| cystathionine beta-synthase [Pse... 620 1e-175 gi|271969755|ref|YP_003343951.1| cystathionine beta-synthase [St... 619 4e-175 >gi|15840513|ref|NP_335550.1| cysteine synthase/cystathionine beta-synthase family protein [Mycobacterium tuberculosis CDC1551] gi|31792268|ref|NP_854761.1| cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (hemoprotein H-450) [Mycobacterium bovis AF2122/97] gi|57116820|ref|YP_177782.1| cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (hemoprotein H-450) [Mycobacterium tuberculosis H37Rv] 73 more sequence titles Length=464 Score = 925 bits (2391), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/464 (100%), Positives = 464/464 (100%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ Sbjct 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI Sbjct 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP Sbjct 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR Sbjct 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 >gi|289749609|ref|ZP_06508987.1| cystathionine beta-synthase cbs [Mycobacterium tuberculosis T92] gi|289690196|gb|EFD57625.1| cystathionine beta-synthase cbs [Mycobacterium tuberculosis T92] Length=464 Score = 924 bits (2387), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/464 (99%), Positives = 464/464 (100%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVK+IEAAEASGQ Sbjct 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKVIEAAEASGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI Sbjct 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP Sbjct 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR Sbjct 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 >gi|289744817|ref|ZP_06504195.1| cysteine synthase/cystathionine beta-synthase [Mycobacterium tuberculosis 02_1987] gi|289685345|gb|EFD52833.1| cysteine synthase/cystathionine beta-synthase [Mycobacterium tuberculosis 02_1987] Length=462 Score = 885 bits (2287), Expect = 0.0, Method: Compositional matrix adjust. Identities = 444/450 (99%), Positives = 445/450 (99%), Gaps = 0/450 (0%) Query 15 PLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGN 74 P+ R VPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGN Sbjct 13 PVARAGPAVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQLKPGGTIVEPTSGN 72 Query 75 TGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDR 134 TGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDR Sbjct 73 TGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAVPPHDPASYYSVSDR 132 Query 135 LVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLK 194 LVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLK Sbjct 133 LVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGIGTGGTITGAGRYLK 192 Query 195 EVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDM 254 EVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDM Sbjct 193 EVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVPDEIIAVSDSDSFDM 252 Query 255 TRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSY 314 TRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSY Sbjct 253 TRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRGYMSKIFNDAWMSSY 312 Query 315 GFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAE 374 GFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAE Sbjct 313 GFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGILREYGVSQMPVVGAE 372 Query 375 PPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWD 434 PPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWD Sbjct 373 PPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAGELVSAAGKALRDWD 432 Query 435 ALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ALMVVEEGKPVGVITRYDLLGFLSEGAGRR Sbjct 433 ALMVVEEGKPVGVITRYDLLGFLSEGAGRR 462 >gi|240170290|ref|ZP_04748949.1| putative cystathionine beta-synthase [Mycobacterium kansasii ATCC 12478] Length=464 Score = 847 bits (2188), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/464 (94%), Positives = 452/464 (98%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLNSVVPDGA TVAAK+EYL+PGGSSKDRIAVKMI+AAE SGQ Sbjct 1 MRIAQHISDLIGGTPLVRLNSVVPDGAATVAAKIEYLSPGGSSKDRIAVKMIDAAEVSGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQRRGY+CVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQRRGYRCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP SYYSVSDRLVR+IDGAWKPDQYANPEGPASHY TTGPEIWADT+GKVTHFVAGI Sbjct 121 PPADPDSYYSVSDRLVREIDGAWKPDQYANPEGPASHYATTGPEIWADTDGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRVRI+GADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPS+P Sbjct 181 GTGGTITGAGRYLKEVSGGRVRIIGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREEA+LVGGSCGMAVVAALKVAE AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEALLVGGSCGMAVVAALKVAETAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLR+RLDGSTE++TVGDVLRRKSGALP LVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRTRLDGSTEEATVGDVLRRKSGALPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVS HMSPPL+MIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSQHMSPPLKMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS A KALRD DALMVVEEGKPVGVITRYDLLGFLSEGAGRR Sbjct 421 ELVSVAEKALRDSDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 >gi|183984361|ref|YP_001852652.1| cystathionine beta-synthase CBS [Mycobacterium marinum M] gi|183177687|gb|ACC42797.1| cystathionine beta-synthase Cbs [Mycobacterium marinum M] Length=464 Score = 838 bits (2166), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/464 (93%), Positives = 448/464 (97%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLN+VVP G GTVAAKVEYLNPGGSSKDRIA+KMI+AAEASG Sbjct 1 MRIAQHISDLIGGTPLVRLNAVVPAGIGTVAAKVEYLNPGGSSKDRIAIKMIDAAEASGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQ RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP SYYSVSDRLVR+IDGAWKPDQYANPEGPASHY TTGPEIWADT+GK+THFVAGI Sbjct 121 PPEDPDSYYSVSDRLVREIDGAWKPDQYANPEGPASHYATTGPEIWADTDGKITHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGG+VR++GADPEGSVYSGG GRPYLVEGVGEDFWPAAYDP+VP Sbjct 181 GTGGTITGAGRYLKEVSGGKVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPAVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAAL+VAE+AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALRVAEQAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDG T+ STVGDVLRRKSGALPALVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGRTDASTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVF G+AKLADAVS HMSPPL++IGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFSGKAKLADAVSQHMSPPLKLIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELV AGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA RR Sbjct 421 ELVGVAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGALRR 464 >gi|254820655|ref|ZP_05225656.1| cystathionine beta-synthase [Mycobacterium intracellulare ATCC 13950] Length=468 Score = 834 bits (2154), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/468 (93%), Positives = 447/468 (96%), Gaps = 4/468 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLNSVVPDGAG VAAKVEYLNPGGSSKDRIAVKMI+AAEASGQ Sbjct 1 MRIAQHISDLIGGTPLVRLNSVVPDGAGIVAAKVEYLNPGGSSKDRIAVKMIDAAEASGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQ RGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLV +I+GAWKPDQYANPEGPASHY TTGPEIWADT+GKVTHFVAGI Sbjct 121 PPDHPDSYYSVSDRLVTEIEGAWKPDQYANPEGPASHYATTGPEIWADTDGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKE+S G VRI+GADPEGSVYSGG GRPYLVEGVGEDFWP AYD +VP Sbjct 181 GTGGTITGAGRYLKEISNGAVRIIGADPEGSVYSGGTGRPYLVEGVGEDFWPQAYDRTVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAAL+VAE+AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALRVAEQAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGSTEQS VGDVLRRKSGALP LVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSRVGDVLRRKSGALPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HMSPPL MIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVAQHMSPPLPMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG----AGRR 464 EL+SAAG ALRDWDALMVVEEGKPVGVITRYDLLGFLSEG +GRR Sbjct 421 ELISAAGTALRDWDALMVVEEGKPVGVITRYDLLGFLSEGPRGLSGRR 468 >gi|342861668|ref|ZP_08718314.1| cystathionine beta-synthase [Mycobacterium colombiense CECT 3035] gi|342130802|gb|EGT84098.1| cystathionine beta-synthase [Mycobacterium colombiense CECT 3035] Length=468 Score = 831 bits (2147), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/468 (93%), Positives = 447/468 (96%), Gaps = 4/468 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLNSVVPDGAG VAAKVEYLNPGGSSKDRIAVKMI+AAEASGQ Sbjct 1 MRIAQHISDLIGGTPLVRLNSVVPDGAGIVAAKVEYLNPGGSSKDRIAVKMIDAAEASGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQ RGYKCVFVCPDKVSEDKRNVL+AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLMAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLV +IDGAWKPDQYANPEGPASHY TTGPEIWADT+GKVTHFVAGI Sbjct 121 PPEHPDSYYSVSDRLVTEIDGAWKPDQYANPEGPASHYATTGPEIWADTDGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGG VRI+GADPEGSVYSGG GRPYLVEGVGEDFWP AYD +VP Sbjct 181 GTGGTITGAGRYLKEVSGGAVRIIGADPEGSVYSGGTGRPYLVEGVGEDFWPQAYDRTVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAE+AGPD+++VVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEQAGPDSIVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGST+QS VGDVLRRKSG LP LVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTDQSRVGDVLRRKSGELPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HMSPPL MIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVALHMSPPLPMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG----AGRR 464 E VSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS+G +GRR Sbjct 421 ESVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSDGPRGLSGRR 468 >gi|118616093|ref|YP_904425.1| cystathionine beta-synthase CBS [Mycobacterium ulcerans Agy99] gi|118568203|gb|ABL02954.1| cystathionine beta-synthase Cbs [Mycobacterium ulcerans Agy99] Length=464 Score = 831 bits (2146), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/464 (92%), Positives = 445/464 (96%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLN+VVP G GTVAAKVEYLNPGGSSKDRIA+KMI+AAEASG Sbjct 1 MRIAQHISDLIGGTPLVRLNAVVPAGIGTVAAKVEYLNPGGSSKDRIAIKMIDAAEASGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQ RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP SYYSVSDRLVR+IDGAWKPDQYANPEGPASHY TTGPEIWADT+GK+THFVAGI Sbjct 121 PPEDPDSYYSVSDRLVREIDGAWKPDQYANPEGPASHYATTGPEIWADTDGKITHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAG YLKEVSGG+VR++GADPEGSVYSGG GRPYLVEGVGEDFWPA YD +VP Sbjct 181 GTGGTITGAGCYLKEVSGGKVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPATYDHAVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAAL+VAE+AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALRVAEQAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDG T+ STVGDVLRRKSGALPALVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGRTDTSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVF G+AKLADAVS HMSPPL++IGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFSGKAKLADAVSQHMSPPLKLIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELV AGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA RR Sbjct 421 ELVGVAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGALRR 464 >gi|289761215|ref|ZP_06520593.1| cystathionine beta-synthase cbs [Mycobacterium tuberculosis GM 1503] gi|289708721|gb|EFD72737.1| cystathionine beta-synthase cbs [Mycobacterium tuberculosis GM 1503] Length=416 Score = 830 bits (2143), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/416 (99%), Positives = 416/416 (100%), Gaps = 0/416 (0%) Query 49 VKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIA 108 +KMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIA Sbjct 1 MKMIEAAEASGQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIA 60 Query 109 YGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWAD 168 YGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWAD Sbjct 61 YGAEVVVCPTAVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWAD 120 Query 169 TEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGE 228 TEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGE Sbjct 121 TEGKVTHFVAGIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGE 180 Query 229 DFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDA 288 DFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDA Sbjct 181 DFWPAAYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDA 240 Query 289 LIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTH 348 LIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTH Sbjct 241 LIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTH 300 Query 349 PSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSA 408 PSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSA Sbjct 301 PSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSA 360 Query 409 HMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 HMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR Sbjct 361 HMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 416 >gi|41407122|ref|NP_959958.1| CysM2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118464016|ref|YP_880447.1| cystathionine beta-synthase [Mycobacterium avium 104] gi|254774084|ref|ZP_05215600.1| cystathionine beta-synthase [Mycobacterium avium subsp. avium ATCC 25291] gi|41395473|gb|AAS03341.1| CysM2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118165303|gb|ABK66200.1| cystathionine beta-synthase [Mycobacterium avium 104] gi|336461455|gb|EGO40325.1| cystathionine beta-synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=468 Score = 827 bits (2135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/468 (92%), Positives = 446/468 (96%), Gaps = 4/468 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLNSVVPDGAG VAAKVEYLNPGGSSKDRIAV+MI+AAEASG Sbjct 1 MRIAQHISDLIGGTPLVRLNSVVPDGAGIVAAKVEYLNPGGSSKDRIAVRMIDAAEASGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKV EDKRNVL+AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVGEDKRNVLMAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLV +I+GAWKPDQYANPEGPASHY TTGPEIWADT+GKVTHFVAGI Sbjct 121 PPEHPDSYYSVSDRLVTEIEGAWKPDQYANPEGPASHYATTGPEIWADTDGKVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRVR++GADPEGSVYSGG GRPYLVEGVGEDFWP AYD +VP Sbjct 181 GTGGTITGAGRYLKEVSGGRVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPQAYDRTVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSDSDSF+MTRRLAREEAMLVGGSCGMAVVAAL+VAE+AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDSDSFNMTRRLAREEAMLVGGSCGMAVVAALRVAEQAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YM+KIFNDAWMSSYGFLR+RLDGST+QS VGDVLRRKSG LP LVHTHPSETVRDAIGIL Sbjct 301 YMAKIFNDAWMSSYGFLRTRLDGSTDQSRVGDVLRRKSGELPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVS HMSPPL MIGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSLHMSPPLPMIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG----AGRR 464 E VSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG GRR Sbjct 421 ESVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGPRGSGGRR 468 >gi|296169941|ref|ZP_06851550.1| cystathionine beta-synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895405|gb|EFG75110.1| cystathionine beta-synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=472 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/472 (92%), Positives = 446/472 (95%), Gaps = 8/472 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHISELIGGTPLVRL SVVPDGAG VAAKVEYLNPGGSSKDRIA +MI+AAEA+G Sbjct 1 MRIAQHISELIGGTPLVRLKSVVPDGAGIVAAKVEYLNPGGSSKDRIAARMIDAAEATGL 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKV EDKRNVL+AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVGEDKRNVLLAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRL R+I+GAWKPDQYANPEGPASHY TTGPEIWADT+GK+THFVAGI Sbjct 121 PPEHPDSYYSVSDRLTREIEGAWKPDQYANPEGPASHYATTGPEIWADTDGKITHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGR----VRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYD 236 GTGGTITGAGRYLKEVS GR VRI+GADPEGSVYSGG GRPYLVEGVGEDFWPAAYD Sbjct 181 GTGGTITGAGRYLKEVSAGRPEGPVRIIGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYD 240 Query 237 PSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPD 296 P VPDE+IAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPD Sbjct 241 PGVPDEVIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPD 300 Query 297 GGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDA 356 GGRGYM+KIFNDAWMSSYGFLRSRLDGSTEQ+ VGDVLRRKSG LP LVHTHPSETVRDA Sbjct 301 GGRGYMAKIFNDAWMSSYGFLRSRLDGSTEQARVGDVLRRKSGELPDLVHTHPSETVRDA 360 Query 357 IGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRM 416 IGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVS HMSPPL M Sbjct 361 IGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSQHMSPPLPM 420 Query 417 IGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG----AGRR 464 IGAGELVSAAGKALR+WDALMVVEEGKPVGVITRYDLLGFLS+G AGRR Sbjct 421 IGAGELVSAAGKALREWDALMVVEEGKPVGVITRYDLLGFLSDGPRGPAGRR 472 >gi|15828289|ref|NP_302552.1| cystathionine [beta]-synthase [Mycobacterium leprae TN] gi|221230766|ref|YP_002504182.1| cystathionine beta-synthase [Mycobacterium leprae Br4923] gi|13093982|emb|CAC31912.1| cystathionine [beta]-synthase [Mycobacterium leprae] gi|219933873|emb|CAR72494.1| cystathionine [beta]-synthase [Mycobacterium leprae Br4923] Length=464 Score = 807 bits (2084), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/464 (91%), Positives = 432/464 (94%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQHIS+LIGGTPLVRLNSVVP G G VAAKVEY N GGSSKDRIA KMI+AAEASGQ Sbjct 1 MRIAQHISDLIGGTPLVRLNSVVPAGTGVVAAKVEYFNSGGSSKDRIAAKMIDAAEASGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ RGYKCVFVCPDKVSEDKRNVL+AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQHRGYKCVFVCPDKVSEDKRNVLLAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP SYYSVSDRLV IDGAWKPDQYANP GPASHY TTGPEIWADT+G+VTHFVAGI Sbjct 121 PPDDPDSYYSVSDRLVAKIDGAWKPDQYANPAGPASHYETTGPEIWADTDGRVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG VRI+GADPEGSVYSGG GRPYLVEGVGEDFWPAAYDP VP Sbjct 181 GTGGTITGVGRYLKEVSGGLVRIIGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPMVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 D+IIAVSDSDSF+MTRRLAREEAMLVGGSCGMAVVAAL+VAEEAGP AL+VVLLPDGGRG Sbjct 241 DQIIAVSDSDSFNMTRRLAREEAMLVGGSCGMAVVAALQVAEEAGPAALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGSTEQ VGDVLRRKSGALP LVHTHPSETVRDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQPIVGDVLRRKSGALPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REY VSQ+PVVGAEPPVMAGEV GSVSERELLSAVFEGRA LADAVS HM PPLR+IG G Sbjct 361 REYAVSQIPVVGAEPPVMAGEVVGSVSERELLSAVFEGRASLADAVSEHMGPPLRLIGDG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS AG+ALRD DALMVVE+GK VGVITRYDLLGFLSEGA R Sbjct 421 ELVSVAGEALRDSDALMVVEKGKLVGVITRYDLLGFLSEGAPLR 464 >gi|120405626|ref|YP_955455.1| cystathionine beta-synthase [Mycobacterium vanbaalenii PYR-1] gi|119958444|gb|ABM15449.1| cystathionine beta-synthase [Mycobacterium vanbaalenii PYR-1] Length=464 Score = 798 bits (2061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/464 (88%), Positives = 438/464 (95%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+HISELIG TPLV+LNSVVP GAGTVAAK+EYLNPGGSSKDRIA+KMI+AAEASG+ Sbjct 1 MRIARHISELIGNTPLVQLNSVVPPGAGTVAAKIEYLNPGGSSKDRIAIKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLA+VAQ+RGYKC+FVCPDKVSEDK+NVL AYGA+VVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLAIVAQQRGYKCIFVCPDKVSEDKQNVLRAYGADVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DPASYYSVS+RLV +IDGAWKPDQY+NP GP SHY TTGPEIWADT+GKVTHFVAG+ Sbjct 121 APEDPASYYSVSNRLVEEIDGAWKPDQYSNPMGPESHYETTGPEIWADTDGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRV+++G DPEGSVYSGG GRPYLVEGVGEDFWPAAYDPSVP Sbjct 181 GTGGTITGAGRYLKEVSGGRVKVIGVDPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREEA+LVGGSCGMA VAA+KVAE GPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEALLVGGSCGMAAVAAIKVAEREGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFNDAWMSSYGFLRSRLDGS E+STVGDVLR KSGALP LVHTHPSETVRDAIGIL Sbjct 301 YLSKIFNDAWMSSYGFLRSRLDGSVEESTVGDVLRGKSGALPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HM PPL +IG G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVADHMGPPLPLIGVG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS A KALR+ DA+MVVEEGKPVGV+TR+DLLG+LSEG RR Sbjct 421 ELVSTAAKALRESDAVMVVEEGKPVGVLTRHDLLGYLSEGNARR 464 >gi|126436951|ref|YP_001072642.1| cystathionine beta-synthase [Mycobacterium sp. JLS] gi|126236751|gb|ABO00152.1| cystathionine beta-synthase [Mycobacterium sp. JLS] Length=464 Score = 796 bits (2055), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/464 (87%), Positives = 440/464 (95%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQH+SELIG TPLV+LNSVVP+GAGTVAAK+EYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIAQHVSELIGNTPLVQLNSVVPEGAGTVAAKIEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKC+FVCPDKVSEDKRNVL AYGA+VVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCIFVCPDKVSEDKRNVLRAYGADVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DP SYYSVS+RLV +I+GAWKPDQY+NP GP SHY TTGPEIW DT+GKVTHFVAG+ Sbjct 121 APDDPDSYYSVSNRLVTEIEGAWKPDQYSNPMGPESHYETTGPEIWRDTDGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGG+VR++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDP+VP Sbjct 181 GTGGTITGAGRYLKEVSGGKVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPAVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREE +LVGGSCGMAVVAA++VA++AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAVVAAIEVAQKAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND+WMSSYGFLR+RLDGS EQ TVGDVLR KSG LP LVHTHPSETVRDAIGIL Sbjct 301 YLSKIFNDSWMSSYGFLRNRLDGSIEQPTVGDVLRGKSGELPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HMSPP+ +IGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVAEHMSPPMPLIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS A K LR+ DALMVVEEGKPVGV+TR+DLLGFLS+G+ RR Sbjct 421 ELVSTAAKTLRECDALMVVEEGKPVGVVTRHDLLGFLSDGSTRR 464 >gi|108801113|ref|YP_641310.1| cystathionine beta-synthase [Mycobacterium sp. MCS] gi|119870254|ref|YP_940206.1| cystathionine beta-synthase [Mycobacterium sp. KMS] gi|108771532|gb|ABG10254.1| cystathionine beta-synthase [Mycobacterium sp. MCS] gi|119696343|gb|ABL93416.1| cystathionine beta-synthase [Mycobacterium sp. KMS] Length=464 Score = 795 bits (2052), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/464 (87%), Positives = 440/464 (95%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQH+SELIG TPLV+LNSVVP+GAGTVAAK+EYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIAQHVSELIGNTPLVQLNSVVPEGAGTVAAKIEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGT+VEPTSGNTGVGLALVAQ+RGYKC+FVCPDKVSEDKRNVL AYGA+VVVCPTAV Sbjct 61 LKPGGTLVEPTSGNTGVGLALVAQQRGYKCIFVCPDKVSEDKRNVLRAYGADVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DP SYYSVS+RLV +I+GAWKPDQY+NP GP SHY TTGPEIW DT+GKVTHFVAG+ Sbjct 121 APDDPDSYYSVSNRLVTEIEGAWKPDQYSNPMGPESHYETTGPEIWRDTDGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGG+VR++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDP+VP Sbjct 181 GTGGTITGAGRYLKEVSGGKVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPAVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREE +LVGGSCGMAVVAA++VA++AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAVVAAIEVAQKAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND+WMSSYGFLR+RLDGS EQ TVGDVLR KSG LP LVHTHPSETVRDAIGIL Sbjct 301 YLSKIFNDSWMSSYGFLRNRLDGSIEQPTVGDVLRGKSGELPDLVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HMSPP+ +IGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVAEHMSPPMPLIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS A K LR+ DALMVVEEGKPVGV+TR+DLLGFLS+G+ RR Sbjct 421 ELVSTAAKTLRECDALMVVEEGKPVGVVTRHDLLGFLSDGSTRR 464 >gi|145222631|ref|YP_001133309.1| cystathionine beta-synthase [Mycobacterium gilvum PYR-GCK] gi|315443096|ref|YP_004075975.1| cystathionine beta-synthase [Mycobacterium sp. Spyr1] gi|145215117|gb|ABP44521.1| cystathionine beta-synthase [Mycobacterium gilvum PYR-GCK] gi|315261399|gb|ADT98140.1| cystathionine beta-synthase [Mycobacterium sp. Spyr1] Length=464 Score = 788 bits (2035), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/461 (87%), Positives = 437/461 (95%), Gaps = 0/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+HISELIG TPLV+LNSVVP GAGTV AKVEYLNPGGSSKDRIA+KMI+AAEASG+ Sbjct 1 MRIARHISELIGNTPLVQLNSVVPPGAGTVVAKVEYLNPGGSSKDRIAIKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLA+VAQ+RGYKC+FVCPDKVSEDK+NVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLAIVAQQRGYKCIFVCPDKVSEDKQNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DPASYYSVS+RLV +IDGAWKPDQY+NP GP SHY TTGPEIWADT+GK+THFVAG+ Sbjct 121 APDDPASYYSVSNRLVSEIDGAWKPDQYSNPMGPESHYETTGPEIWADTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGGRV+++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDPSVP Sbjct 181 GTGGTITGAGRYLKEVSGGRVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREEA+LVGGSCGMA VAA++VAE GPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEALLVGGSCGMAAVAAIRVAEREGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WMSSYGFLR+RLDGS ++STVGDVLR KSGALPALVHTHPSETVRDAIGIL Sbjct 301 YLSKIFNDGWMSSYGFLRTRLDGSVQESTVGDVLRGKSGALPALVHTHPSETVRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSER+L+SAVFEGRAKLADAV+ HMSPPL +IGAG Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERDLVSAVFEGRAKLADAVAQHMSPPLPLIGAG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 ELVSAA K LR+ DA+MVVEEGKP GV+TR+DLLG+LS+ + Sbjct 421 ELVSAAAKTLRECDAVMVVEEGKPAGVLTRHDLLGYLSDSS 461 >gi|118472959|ref|YP_889516.1| cystathionine beta-synthase [Mycobacterium smegmatis str. MC2 155] gi|118174246|gb|ABK75142.1| cystathionine beta-synthase [Mycobacterium smegmatis str. MC2 155] Length=463 Score = 785 bits (2028), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/464 (87%), Positives = 435/464 (94%), Gaps = 1/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+HISELIG TPLV+LNSVVP+GAG VAAK+EYLNPGGSSKDRIA+KMIEAAE SG+ Sbjct 1 MRIARHISELIGNTPLVQLNSVVPEGAGLVAAKIEYLNPGGSSKDRIALKMIEAAEVSGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVS+RLV +I+GAWKPDQY+N GP SHY TTGPEIWADTEGK+THFVAG+ Sbjct 121 PPDHPDSYYSVSNRLVTEIEGAWKPDQYSNQMGPESHYETTGPEIWADTEGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG+V+++GADPEGSVYSGG GRPYLVEGVGEDFWP AYDPSVP Sbjct 181 GTGGTITGTGRYLKEVSGGKVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPTAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREEA+LVGGSCGMAVVAA++VA +AGPDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEALLVGGSCGMAVVAAIEVARKAGPDAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFNDAWMSSYGFLR+RLDGS E+ TVGDVLR KSGALP LVHTHPSETVRDAIGIL Sbjct 301 YLSKIFNDAWMSSYGFLRTRLDGSVEK-TVGDVLRGKSGALPDLVHTHPSETVRDAIGIL 359 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV+ HMSPPL +IGAG Sbjct 360 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVAEHMSPPLPLIGAG 419 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 ELVS A K LR+ DA+MVVE+GKPVGV+TR+DLLGFLSEG R Sbjct 420 ELVSTAAKTLRESDAVMVVEDGKPVGVLTRHDLLGFLSEGGYRH 463 >gi|169628288|ref|YP_001701937.1| cystathionine beta-synthase [Mycobacterium abscessus ATCC 19977] gi|169240255|emb|CAM61283.1| Probable cystathionine beta-synthase [Mycobacterium abscessus] Length=469 Score = 769 bits (1986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/468 (85%), Positives = 431/468 (93%), Gaps = 4/468 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIAQH+S+LIG TPLVRLNSVVP+G TVAAK+EYLNPGGSSKDRIAVKMIEAAE +G Sbjct 1 MRIAQHVSDLIGNTPLVRLNSVVPEGCATVAAKIEYLNPGGSSKDRIAVKMIEAAEEAGL 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQR+GY CVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQRKGYHCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYY+VSDRLVR+I+GAWKPDQY+NP GPASHY TTGPEIWADT+GK+THFVAG+ Sbjct 121 PPEHPDSYYNVSDRLVREIEGAWKPDQYSNPNGPASHYETTGPEIWADTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGR----VRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYD 236 GTGGTITGAGRYLKEVSGGR V+IVGADPEGSVYSGG GRPYLVEGVGEDFWP+AYD Sbjct 181 GTGGTITGAGRYLKEVSGGRAIGEVKIVGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYD 240 Query 237 PSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPD 296 PSV DE+IAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAA+++AE+ GPD L+VVLLPD Sbjct 241 PSVVDEVIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAAIRLAEKVGPDGLVVVLLPD 300 Query 297 GGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDA 356 GGRGY+SK+FNDAWMSSYGFLRSRLDGS + TVGDVLR KSGALP LVHTHPSETVRDA Sbjct 301 GGRGYLSKVFNDAWMSSYGFLRSRLDGSVSEPTVGDVLRGKSGALPDLVHTHPSETVRDA 360 Query 357 IGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRM 416 I ILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRA+LADAV+ HMSPPL + Sbjct 361 IEILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAQLADAVAQHMSPPLPL 420 Query 417 IGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 +G+GE +S AG LRD DA+MVV+EGKPVGVITR+DLLGF+S G G R Sbjct 421 VGSGEPLSTAGSMLRDTDAVMVVDEGKPVGVITRHDLLGFVSSGRGVR 468 >gi|333989663|ref|YP_004522277.1| cystathionine beta-synthase CBS [Mycobacterium sp. JDM601] gi|333485631|gb|AEF35023.1| cystathionine beta-synthase CBS [Mycobacterium sp. JDM601] Length=464 Score = 762 bits (1968), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/464 (86%), Positives = 428/464 (93%), Gaps = 0/464 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+HIS+LIG TPLV LNS+VPDGAG V AK+EYLNPG SSKDRIAVKMI+AAEASG Sbjct 1 MRIARHISDLIGNTPLVELNSIVPDGAGRVVAKIEYLNPGASSKDRIAVKMIDAAEASGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDK+NV+ AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKQNVMRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DPASYYSVS+RLV +IDGAWKPDQY+N GP SHY TTGPEIW+DT+G+VTHFVAGI Sbjct 121 PPDDPASYYSVSNRLVEEIDGAWKPDQYSNQAGPESHYETTGPEIWSDTDGQVTHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGGRVR++GADPEGSVYSGG GRPYLVEGVGEDFWPAAYDP VP Sbjct 181 GTGGTITGTGRYLKEVSGGRVRVIGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPKVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREEA+LVGGSCGMAVVAA++ A +AGPDAL+VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEALLVGGSCGMAVVAAVEAAVKAGPDALVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLRSRLDGST + TV DVLR KSG LP LVHTHP+ET+RDAIGIL Sbjct 301 YMSKIFNDAWMSSYGFLRSRLDGSTVEPTVADVLRVKSGVLPDLVHTHPAETLRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSER+LLSAVFEGRAKLADAVS HM PPL +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERDLLSAVFEGRAKLADAVSQHMGPPLPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGAGRR 464 E+V A L D DA+MVVE+GKPVGVITR+DLLGFLS+G RR Sbjct 421 EVVGVAATTLADVDAVMVVEDGKPVGVITRHDLLGFLSDGPRRR 464 >gi|226307753|ref|YP_002767713.1| cystathionine beta-synthase [Rhodococcus erythropolis PR4] gi|229491948|ref|ZP_04385768.1| cystathionine beta-synthase [Rhodococcus erythropolis SK121] gi|21280312|dbj|BAB96806.1| probable cystathionine beta-synthase [Rhodococcus erythropolis] gi|226186870|dbj|BAH34974.1| cystathionine beta-synthase [Rhodococcus erythropolis PR4] gi|229321161|gb|EEN86962.1| cystathionine beta-synthase [Rhodococcus erythropolis SK121] Length=461 Score = 746 bits (1925), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/458 (83%), Positives = 417/458 (92%), Gaps = 0/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+H+ +LIG TPLV+L SV + GTVAAKVEYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIAEHVVDLIGNTPLVKLTSVTGENFGTVAAKVEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTG+GLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGIGLALVAQKRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P +P SYYSVSDRL R+I GAWKP+QY+NP GP SHY TTGPEIWADT+GK+THFVAG+ Sbjct 121 APDNPNSYYSVSDRLTREIPGAWKPNQYSNPGGPESHYETTGPEIWADTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG+V+++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDPS+P Sbjct 181 GTGGTITGTGRYLKEVSGGKVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VA+ GPDALIVVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALEVAKREGPDALIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+SYGFLR+ LDG T TVGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 301 YLSKIFNDQWMASYGFLRTPLDGKTNVPTVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSER+LLSAVFEGRA LAD+V HMS P +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERDLLSAVFEGRAHLADSVEKHMSKPFPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E VSAA KAL D DALMVV++GKPVGVITR+DLLGFLS Sbjct 421 EPVSAATKALGDTDALMVVDDGKPVGVITRHDLLGFLS 458 >gi|343925073|ref|ZP_08764605.1| cystathionine beta-synthase [Gordonia alkanivorans NBRC 16433] gi|343765004|dbj|GAA11531.1| cystathionine beta-synthase [Gordonia alkanivorans NBRC 16433] Length=464 Score = 742 bits (1916), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/458 (83%), Positives = 415/458 (91%), Gaps = 0/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +L+G TPLV+LNSV G+G VAAKVEYLNPGGSSKDRIAV+MI+AAEASG+ Sbjct 1 MRIANHVVDLVGNTPLVKLNSVTTPGSGLVAAKVEYLNPGGSSKDRIAVRMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTI+EPTSGNTGVGLALVAQ+RGYKCVFVCPDKV EDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIIEPTSGNTGVGLALVAQQRGYKCVFVCPDKVGEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLVR+I+G WKP+QYANP GP SHY TTGPEIWADT+GKVTHFVAG+ Sbjct 121 PPEHPDSYYSVSDRLVREIEGGWKPNQYANPAGPQSHYETTGPEIWADTDGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVS G V++VG DPEGSVYSGG GRPYLVEGVGEDFWPAAYDPS+P Sbjct 181 GTGGTITGTGRYLKEVSNGAVKVVGVDPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREE +LVGGSCGMAVVAAL+VAE GPDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAVVAALQVAEREGPDAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YM+KIFND WMSSYGFLR+ LD +T++S VGDVLR K+GALP LVHTHP ET+RDAI IL Sbjct 301 YMAKIFNDEWMSSYGFLRTPLDANTKESLVGDVLRGKTGALPDLVHTHPQETLRDAIEIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAG+V+ER+LLSAVFEGRA LAD VSAHM P +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGAVTERDLLSAVFEGRASLADPVSAHMGDPFPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E VSAA KAL D DALMVVE+GKP+GVITR+DLL F+S Sbjct 421 EPVSAATKALGDSDALMVVEDGKPIGVITRHDLLAFVS 458 >gi|111022806|ref|YP_705778.1| cystathionine beta-synthase [Rhodococcus jostii RHA1] gi|110822336|gb|ABG97620.1| probable cystathionine beta-synthase [Rhodococcus jostii RHA1] Length=461 Score = 739 bits (1909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/461 (81%), Positives = 418/461 (91%), Gaps = 0/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+H+ +LIG TPLV+L+SV+ + GTVAAK+EYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIAEHVVDLIGNTPLVKLSSVIGENHGTVAAKIEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTG+GLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGIGLALVAQKRGYKCVFVCPDKVSEDKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYYSVSDRL R++ G WKP+QY+NP GP SHY TTGPEIWADT+GK+THFVAG+ Sbjct 121 APEHPDSYYSVSDRLARELPGGWKPNQYSNPGGPQSHYETTGPEIWADTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG+V+++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDPS+P Sbjct 181 GTGGTITGTGRYLKEVSGGKVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VA+ GPDA+IVVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALEVAKREGPDAVIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+SYGFLR+ LDG ++ TVGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 301 YLSKIFNDKWMASYGFLRTPLDGKPDEKTVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSV+ER+LLSAVFEGRA LAD V HMS P +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVTERDLLSAVFEGRAHLADPVEKHMSKPFPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 E VSAA KAL D DALMVV++GKP GVITR+DLLGFLS G+ Sbjct 421 EPVSAATKALGDTDALMVVDDGKPAGVITRHDLLGFLSAGS 461 >gi|54026806|ref|YP_121048.1| putative cystathionine beta-synthase [Nocardia farcinica IFM 10152] gi|54018314|dbj|BAD59684.1| putative cystathionine beta-synthase [Nocardia farcinica IFM 10152] Length=462 Score = 739 bits (1908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/461 (83%), Positives = 419/461 (91%), Gaps = 2/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +LIG TPLVRLN+VV AG VAAK+EYLNPGGSSKDRIAVKMI+AAE SGQ Sbjct 1 MRIADHVVDLIGNTPLVRLNNVVGPNAGLVAAKIEYLNPGGSSKDRIAVKMIDAAEKSGQ 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLVR+IDGAWKPDQY+NP GP SHY TTGPEIW DT+G+VTHFVAG+ Sbjct 121 PPDHPDSYYSVSDRLVREIDGAWKPDQYSNPGGPESHYETTGPEIWRDTDGRVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITGAGRYLKEVSGG+VR++GADPEGSVYSGG+GRPYLVEGVGEDFWP+AYDP+VP Sbjct 181 GTGGTITGAGRYLKEVSGGKVRVIGADPEGSVYSGGSGRPYLVEGVGEDFWPSAYDPAVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAA++VA PDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAAIEVARR-DPDAVVVVLLPDGGRG 299 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WMSSYGFLR+RLDGS E VGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 300 YLSKIFNDQWMSSYGFLRTRLDGSPE-PLVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 358 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEV GSV+ER+LLSAVFEGRA L D+V+ HMSP +IG+G Sbjct 359 REYGVSQMPVVGAEPPVMAGEVQGSVTERDLLSAVFEGRAHLTDSVAQHMSPSFPLIGSG 418 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 E +SAA KAL D DALMVVE+GKPVGVITR+DLLGFLS G+ Sbjct 419 EPISAATKALSDTDALMVVEDGKPVGVITRHDLLGFLSTGS 459 >gi|226365313|ref|YP_002783096.1| cystathionine beta-synthase [Rhodococcus opacus B4] gi|226243803|dbj|BAH54151.1| cystathionine beta-synthase [Rhodococcus opacus B4] Length=461 Score = 739 bits (1908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/461 (81%), Positives = 417/461 (91%), Gaps = 0/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+H+ +LIG TPLV+L+SV+ + GTVAAK+EYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIAEHVVDLIGNTPLVKLSSVIGENHGTVAAKIEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTG+GLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGIGLALVAQKRGYKCVFVCPDKVSEDKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYYSVSDRL R++ G WKP+QY+NP GP SHY TTGPEIWADT+GK+THFVAG+ Sbjct 121 APEHPDSYYSVSDRLARELPGGWKPNQYSNPGGPQSHYETTGPEIWADTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG+V+++GADPEGSVYSGG GRPYLVEGVGEDFWP AYDPS+P Sbjct 181 GTGGTITGTGRYLKEVSGGKVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPTAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VA+ GPDA+IVVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALEVAKREGPDAVIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+SYGFLR+ LDG ++ TVGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 301 YLSKIFNDKWMASYGFLRTPLDGKPDEKTVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSV+ER+LLSAVFEGRA LAD V HMS P +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGSVTERDLLSAVFEGRAHLADPVEKHMSKPFPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 E VSAA KAL D DALMVV++GKP GVITR+DLLGFLS G+ Sbjct 421 EPVSAATKALGDTDALMVVDDGKPAGVITRHDLLGFLSAGS 461 >gi|262201573|ref|YP_003272781.1| cystathionine beta-synthase [Gordonia bronchialis DSM 43247] gi|262084920|gb|ACY20888.1| cystathionine beta-synthase [Gordonia bronchialis DSM 43247] Length=464 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/458 (82%), Positives = 412/458 (90%), Gaps = 0/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +L+G TPLV+LNSV G+G VAAKVEYLNPGGSSKDRIAV+M++AAE SG+ Sbjct 1 MRIANHVVDLVGNTPLVKLNSVTTPGSGLVAAKVEYLNPGGSSKDRIAVRMVDAAEKSGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKV EDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVGEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRL R+I+GAWKP+QYANP GP SHY TTGPEIW DT+GKVTHFVAG+ Sbjct 121 EPSHPDSYYNVSDRLTREIEGAWKPNQYANPAGPQSHYETTGPEIWNDTDGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVSGG V++VG DPEGSVYSGG GRPYLVEGVGEDFWP AYDPS+P Sbjct 181 GTGGTITGTGRYLKEVSGGAVKVVGVDPEGSVYSGGTGRPYLVEGVGEDFWPEAYDPSIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREE +LVGGSCGMA VAAL+VAE GPDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAAVAALQVAEREGPDAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YM+KIFND WMSSYGFLR+ LDG T++S VGDVLR K+GALP LVHTHPSET+RDAI IL Sbjct 301 YMAKIFNDEWMSSYGFLRTPLDGKTKESLVGDVLRGKTGALPDLVHTHPSETLRDAIEIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAG+V+ER+LLSAVFEGRA LAD VSAHM P +IG+G Sbjct 361 REYGVSQMPVVGAEPPVMAGEVAGAVTERDLLSAVFEGRASLADPVSAHMGDPFPLIGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E VSAA KAL + DALMVVE+GKP+GVITR+DLL F+S Sbjct 421 EPVSAATKALGESDALMVVEDGKPIGVITRHDLLAFVS 458 >gi|325676583|ref|ZP_08156261.1| cystathionine beta-synthase [Rhodococcus equi ATCC 33707] gi|325552761|gb|EGD22445.1| cystathionine beta-synthase [Rhodococcus equi ATCC 33707] Length=460 Score = 734 bits (1894), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/461 (83%), Positives = 416/461 (91%), Gaps = 1/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +LIG TPLV+L+SVV +G VAAKVEYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIADHVVDLIGNTPLVKLSSVVGANSGLVAAKVEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQKRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRLV++I GAWKP+QYANP GP SHY TTGPEIW DTEGKVTHFVAG+ Sbjct 121 APEHPDSYYNVSDRLVKEIPGAWKPNQYANPGGPDSHYETTGPEIWRDTEGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKE+SGG+V+I+GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDPSVP Sbjct 181 GTGGTITGTGRYLKEISGGKVKIIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VAE PDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALEVAER-DPDAVVVVLLPDGGRG 299 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+SYGFLR+ LDG T + TVGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 300 YLSKIFNDEWMASYGFLRTPLDGDTTEPTVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 359 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSER+LLSAVFEGRA LAD V HMS P +IGA Sbjct 360 REYGVSQMPVVGAEPPVMAGEVAGSVSERDLLSAVFEGRAALADPVEKHMSKPFPLIGAQ 419 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 E VS+A KAL + DALMVV++GKPVGVITR+DLLGFLS GA Sbjct 420 EPVSSATKALGETDALMVVDDGKPVGVITRHDLLGFLSAGA 460 >gi|312138725|ref|YP_004006061.1| cystathionine beta synthase cysb [Rhodococcus equi 103S] gi|311888064|emb|CBH47376.1| cystathionine beta synthase CysB [Rhodococcus equi 103S] Length=460 Score = 732 bits (1890), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/461 (83%), Positives = 416/461 (91%), Gaps = 1/461 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +LIG TPLV+L+SVV +G VAAKVEYLNPGGSSKDRIAVKMI+AAEASG+ Sbjct 1 MRIADHVVDLIGNTPLVKLSSVVGANSGLVAAKVEYLNPGGSSKDRIAVKMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQKRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRLV++I GAWKP+QYANP GP SHY TTGPEIW DTEGKVTHFVAG+ Sbjct 121 APEHPDSYYNVSDRLVKEIPGAWKPNQYANPGGPDSHYETTGPEIWRDTEGKVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKE+SGG+V+I+GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDPSVP Sbjct 181 GTGGTITGTGRYLKEISGGKVKIIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPSVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VA+ PDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALEVAKR-DPDAVVVVLLPDGGRG 299 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+SYGFLR+ LDG T + TVGDVLR KSG LP LVHTHPSET+RDAI IL Sbjct 300 YLSKIFNDEWMASYGFLRTPLDGDTTEPTVGDVLRGKSGELPDLVHTHPSETLRDAIEIL 359 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVVGAEPPVMAGEVAGSVSER+LLSAVFEGRA LAD V HMS P +IGA Sbjct 360 REYGVSQMPVVGAEPPVMAGEVAGSVSERDLLSAVFEGRAALADPVEKHMSKPFPLIGAQ 419 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEGA 461 E VS+A KAL + DALMVV++GKPVGVITR+DLLGFLS GA Sbjct 420 EPVSSATKALGETDALMVVDDGKPVGVITRHDLLGFLSAGA 460 >gi|296140835|ref|YP_003648078.1| cystathionine beta-synthase [Tsukamurella paurometabola DSM 20162] gi|296028969|gb|ADG79739.1| cystathionine beta-synthase [Tsukamurella paurometabola DSM 20162] Length=460 Score = 726 bits (1873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/460 (80%), Positives = 410/460 (90%), Gaps = 1/460 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+SELIG TPLVRLNSVV G+G VAAK+EYLNPGGSSKDRIAVKMI+AA+ SG+ Sbjct 1 MRIAGHVSELIGDTPLVRLNSVVTPGSGLVAAKIEYLNPGGSSKDRIAVKMIDAADQSGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLA+VAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLAIVAQQRGYKCVFVCPDKVSEDKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRL R+I GAWKP+QY+NP GPASHY TTGPEIW DTEG++THFVAG+ Sbjct 121 APEHPDSYYNVSDRLTREIPGAWKPNQYSNPNGPASHYETTGPEIWRDTEGRITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKE+SGG V+++GADPEGSVYSGG GRPYLVEGVGEDFWP AYDP +P Sbjct 181 GTGGTITGTGRYLKEISGGAVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPTAYDPDIP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+VAE PDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALRVAER-DPDAVVVVLLPDGGRG 299 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WMSSYGFLR+ LD + +++ VGD+LR K G LP LVHTHPSET+RDAI IL Sbjct 300 YLSKIFNDKWMSSYGFLRTPLDPNEQEALVGDILRGKKGELPDLVHTHPSETIRDAIEIL 359 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EY VSQMPVVGAEPP+MAGEVAG+V+ERELLSAVFEGRA LAD VS HM P +IGAG Sbjct 360 AEYNVSQMPVVGAEPPIMAGEVAGAVTERELLSAVFEGRANLADPVSKHMGPAFPLIGAG 419 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG 460 E +SAA KAL D DALMV+++GKPVGVITR+D+L FLS G Sbjct 420 EPISAANKALSDSDALMVIDDGKPVGVITRHDVLNFLSHG 459 >gi|326381815|ref|ZP_08203508.1| cystathionine beta-synthase [Gordonia neofelifaecis NRRL B-59395] gi|326199241|gb|EGD56422.1| cystathionine beta-synthase [Gordonia neofelifaecis NRRL B-59395] Length=471 Score = 724 bits (1868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/459 (81%), Positives = 409/459 (90%), Gaps = 1/459 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +L+G TPLV+LN VV G+G VAAKVEYLNPGGSSKDRIA +MI+AAEASG+ Sbjct 1 MRIANHVVDLVGNTPLVKLNKVVQPGSGLVAAKVEYLNPGGSSKDRIATRMIDAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKV+EDKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVAEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYY+VSDRL RDI GAWKP+QYANP GP SHY TTGPEIW DT+G VTHFVAG+ Sbjct 121 PPEHPDSYYNVSDRLTRDIPGAWKPNQYANPNGPLSHYETTGPEIWRDTDGTVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKE+S GRV++VG DPEGSVYSGG+GRPYLVEGVGEDFWP AYDP+VP Sbjct 181 GTGGTITGTGRYLKEISDGRVKVVGVDPEGSVYSGGSGRPYLVEGVGEDFWPDAYDPTVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEI+AVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL++AE G DA++VVLLPDGGRG Sbjct 241 DEIVAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALRIAEREGSDAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDG-STEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGI 359 Y+SKIFND WMSSYGFLR+ LDG + +STVGDVLR KSG LP LVHTHP ET+RDAI I Sbjct 301 YLSKIFNDDWMSSYGFLRTPLDGVARTESTVGDVLRGKSGTLPDLVHTHPQETLRDAIEI 360 Query 360 LREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGA 419 LRE+GVSQMPVVGAEPP+ AGEVAG+VSER+LLSAVFEGRA LAD VSAHM P R+IGA Sbjct 361 LREFGVSQMPVVGAEPPITAGEVAGAVSERDLLSAVFEGRANLADPVSAHMGEPFRLIGA 420 Query 420 GELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 GE VS+A +AL DALMVVE+GKPVGVITR+DLL F S Sbjct 421 GEPVSSAMEALSTADALMVVEDGKPVGVITRHDLLAFAS 459 >gi|333921104|ref|YP_004494685.1| putative cystathionine beta-synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333483325|gb|AEF41885.1| Putative cystathionine beta-synthase [Amycolicicoccus subflavus DQS3-9A1] Length=472 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/460 (80%), Positives = 401/460 (88%), Gaps = 0/460 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA+H+ +LIG TPLV+LNSV G VAAK+EYLNPGGSSKDRIA+KM+EAAE G+ Sbjct 11 MRIAEHVVDLIGNTPLVKLNSVADGIPGIVAAKIEYLNPGGSSKDRIALKMVEAAEKEGK 70 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 71 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAV 130 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRL +I G WKPDQY+N GP SHY TTGPEIW DTEGKVTHFVAG+ Sbjct 131 PPDHPDSYYSVSDRLTDEIPGGWKPDQYSNLNGPDSHYETTGPEIWRDTEGKVTHFVAGV 190 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVS G V+I+G DPEGSVYSGG+GRPYLVEGVGEDFWP+AYDP++P Sbjct 191 GTGGTITGTGRYLKEVSNGAVKIIGVDPEGSVYSGGSGRPYLVEGVGEDFWPSAYDPAIP 250 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLARE+ +LVGGSCGMAVV AL+VA GPDA++VVLLPDGGRG Sbjct 251 DEIIAVSDADSFEMTRRLAREDGLLVGGSCGMAVVGALEVARRDGPDAVVVVLLPDGGRG 310 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YMSKIFNDAWMSSYGFLR+RLDGST STVGDVLR KSG LP LVHTHP ET+RDAI I+ Sbjct 311 YMSKIFNDAWMSSYGFLRTRLDGSTAASTVGDVLRGKSGKLPDLVHTHPQETLRDAIEIM 370 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REY VSQMPVVGAEPP+MAGEV GS++ER+LL AVFEGRA LAD VS MS L +IG G Sbjct 371 REYDVSQMPVVGAEPPIMAGEVRGSINERDLLGAVFEGRAHLADPVSKVMSDALPLIGTG 430 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG 460 E V A KAL D DALMVVE+GKP+GVITR+DLL F S G Sbjct 431 ETVEDAQKALADTDALMVVEDGKPIGVITRHDLLVFYSSG 470 >gi|311742687|ref|ZP_07716496.1| cystathionine beta-synthase [Aeromicrobium marinum DSM 15272] gi|311314315|gb|EFQ84223.1| cystathionine beta-synthase [Aeromicrobium marinum DSM 15272] Length=458 Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/455 (79%), Positives = 400/455 (88%), Gaps = 0/455 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H+ +LIGGTPLVRLN V G+G VAAK+EYLNPGGS+KDRIAVKM++ AE SG Sbjct 1 MRIANHVVDLIGGTPLVRLNHVPSPGSGLVAAKIEYLNPGGSAKDRIAVKMVDDAEKSGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTI+EPTSGNTGVGLALVAQ+RGY C+FVCPDKVS DKRN ++AYGAEVVVCPTAV Sbjct 61 LRPGGTIIEPTSGNTGVGLALVAQQRGYHCIFVCPDKVSLDKRNTMMAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYY+VSDRLVR+ DG WKPDQY+NP GP SHY TTGPEIWADT+G VTHFVAG+ Sbjct 121 PPEHPDSYYNVSDRLVRETDGGWKPDQYSNPAGPQSHYETTGPEIWADTDGTVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKEVS GRV +VG DPEGSVYSGG+GRPYLVEGVGEDFWP+AYDP VP Sbjct 181 GTGGTITGVGRYLKEVSDGRVTVVGVDPEGSVYSGGSGRPYLVEGVGEDFWPSAYDPDVP 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSFDMTRRLAREE +LVGGSCGMA VAAL+VAE GPDA++VVLLPDGGRG Sbjct 241 DEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAAVAALQVAEREGPDAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WMSSYGFLR LDGST++ +VG++LRRKSG +PALVHTHP ET+RDAIGIL Sbjct 301 YLSKIFNDEWMSSYGFLREPLDGSTDRPSVGEILRRKSGDIPALVHTHPQETIRDAIGIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EYGVSQMPVVG EPPV+ GEVAGSVSER LL AVFEGRA L D VSAHM P L ++G+G Sbjct 361 HEYGVSQMPVVGPEPPVVIGEVAGSVSERVLLGAVFEGRASLTDPVSAHMEPALPLLGSG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLG 455 E + A LRD DA+MVVE+GKP+GV+TR+DLLG Sbjct 421 EDLDTAITMLRDSDAVMVVEDGKPLGVLTRHDLLG 455 >gi|296394384|ref|YP_003659268.1| cystathionine beta-synthase [Segniliparus rotundus DSM 44985] gi|296181531|gb|ADG98437.1| cystathionine beta-synthase [Segniliparus rotundus DSM 44985] Length=461 Score = 686 bits (1771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/457 (77%), Positives = 396/457 (87%), Gaps = 0/457 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MRIA H++ELIG TPLVRLNSV P GA TVA K+EYLNPG SSKDRIA KM++ AE +G Sbjct 1 MRIAGHVTELIGNTPLVRLNSVAPAGAATVAVKLEYLNPGASSKDRIAAKMVDEAEKAGL 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVF+CPDKVSEDK+NVL AYGA+VVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFICPDKVSEDKQNVLRAYGAQVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRL ++ +GAWKP+QY NP GPASHY +TGPEIW DT+GK+THFVAGI Sbjct 121 PPEHPNSYYSVSDRLAKETEGAWKPNQYVNPAGPASHYESTGPEIWRDTDGKITHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+GAGRYLK+VS G VR+VGADPEGSVYSGG GRPYLVEGVGEDFWP AYD +V Sbjct 181 GTGGTISGAGRYLKDVSDGAVRVVGADPEGSVYSGGTGRPYLVEGVGEDFWPDAYDRTVT 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEI+AVSD+DSF+MTRRLAREE +L+GGS G+AVVAA++VA+ GPD L+V LLPDGGRG Sbjct 241 DEILAVSDADSFNMTRRLAREEGLLLGGSSGLAVVAAIRVAQRIGPDGLVVALLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND+WM SYGFLR+RLDG+ ++ TVG++LR KSG LP+ VHTHP ET+RDAI IL Sbjct 301 YLSKIFNDSWMRSYGFLRTRLDGTADEHTVGEILRGKSGELPSFVHTHPQETIRDAIDIL 360 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EY VSQMPVVGAEPP+M GEVAGSV ERELLSAVF GRA LAD V+ HMSPP IG G Sbjct 361 AEYEVSQMPVVGAEPPIMLGEVAGSVDERELLSAVFSGRASLADPVNKHMSPPFPFIGIG 420 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFL 457 E S A KAL + +ALMVVE+GKPVGVITR DLL FL Sbjct 421 EPFSQAIKALGESNALMVVEDGKPVGVITRQDLLNFL 457 >gi|258654542|ref|YP_003203698.1| cystathionine beta-synthase [Nakamurella multipartita DSM 44233] gi|258557767|gb|ACV80709.1| cystathionine beta-synthase [Nakamurella multipartita DSM 44233] Length=455 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/458 (73%), Positives = 387/458 (85%), Gaps = 5/458 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR AQ + ELIG TPLV+L + D A V AKVEY+NPGGS KDRIAVKMI+AAE SG Sbjct 1 MRYAQSVVELIGNTPLVKLGPLAADVAPLVLAKVEYVNPGGSVKDRIAVKMIDAAEQSGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQ+RGY+C+F+CPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQQRGYRCIFICPDKVSEDKRNVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DP SYYSVSDRLVR+ GAWKPDQY+NP PASHYV+TGPEIW DT+GK+THFV G+ Sbjct 121 APDDPTSYYSVSDRLVRETPGAWKPDQYSNPNNPASHYVSTGPEIWRDTDGKITHFVTGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLK+VSGGRV+++GADPEGSVYSGG GRPYLVEGVGEDFWP+AYDP+V Sbjct 181 GTGGTISGVGRYLKDVSGGRVQVIGADPEGSVYSGGTGRPYLVEGVGEDFWPSAYDPTVT 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 D IIA+SD++SF +TRRLAREE +LVGGSCGMAV AAL++A D ++VVLLPDGGRG Sbjct 241 DGIIAISDAESFAVTRRLAREEGLLVGGSCGMAVAAALRLAGRLTADDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIF+D WM+SYGFL SR DG ++TVG VLR K G LPALVHTHP ETVRDA+ I+ Sbjct 301 YLSKIFSDPWMASYGFL-SR-DG---EATVGQVLRGKGGVLPALVHTHPQETVRDAVEIM 355 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EYGVSQMPVV AEPPVM+GEVAGSVSER+LL A+F G A LADAV HM PP ++G+G Sbjct 356 HEYGVSQMPVVKAEPPVMSGEVAGSVSERDLLDALFAGTASLADAVGKHMGPPFPLVGSG 415 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E V AL+ DA+MV+++GKPVGV+TR DLL F++ Sbjct 416 EDVPTLRAALQARDAVMVIDDGKPVGVLTRADLLAFVA 453 >gi|332671462|ref|YP_004454470.1| cystathionine beta-synthase [Cellulomonas fimi ATCC 484] gi|332340500|gb|AEE47083.1| cystathionine beta-synthase [Cellulomonas fimi ATCC 484] Length=468 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/472 (75%), Positives = 397/472 (85%), Gaps = 19/472 (4%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ A+HISEL+GGTPLVRL+SV TV AKVEYLNPGGS KDRIA+KMIEAAEASG+ Sbjct 1 MKYAEHISELVGGTPLVRLSSVTEGLTATVLAKVEYLNPGGSVKDRIALKMIEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQR+GY+CVFVCPDKVS+DKR+VL AYGAEVVV PTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLALVAQRKGYRCVFVCPDKVSQDKRDVLRAYGAEVVVTPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRL R+I+GAWKP+QYAN GPASHY +TGPEIWADT+G+VTH VAG+ Sbjct 121 PPDHPDSYYSVSDRLAREIEGAWKPNQYANANGPASHYESTGPEIWADTDGRVTHVVAGV 180 Query 181 GTGGTITGAGRYLKEVS-------GGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPA 233 GTGGTITG GR+L +VS GGRV +VGADP GSVYSGG GRPYLVEGVGEDFWP+ Sbjct 181 GTGGTITGTGRFLHDVSADRPEADGGRVVVVGADPLGSVYSGGDGRPYLVEGVGEDFWPS 240 Query 234 AYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEE---AGPD--- 287 AYDPSVPD IIAVSD+DSF MTRRLAREE +LVGGSCGMAV AAL+ A E + PD Sbjct 241 AYDPSVPDRIIAVSDADSFAMTRRLAREEGLLVGGSCGMAVEAALRFARELQDSDPDAAA 300 Query 288 -ALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVH 346 A+IVV+LPDGGRGY+SKIFND+WM SYGFL G+ E +TVGDVLR K+G+LPALVH Sbjct 301 RAVIVVILPDGGRGYLSKIFNDSWMRSYGFL-----GADEGATVGDVLRTKTGSLPALVH 355 Query 347 THPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV 406 THP+E+VRDAI IL EYGVSQMPVVGAEPPV GEVAG+VSER+LL AVF GRA L+D V Sbjct 356 THPTESVRDAIEILHEYGVSQMPVVGAEPPVKVGEVAGAVSERDLLDAVFSGRAALSDRV 415 Query 407 SAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 HM P +IGAGE V A +AL DALMVV++G+PVGV+TR+DLLGFL+ Sbjct 416 DKHMGSPFPLIGAGESVDDARRALESADALMVVDDGQPVGVLTRHDLLGFLA 467 >gi|317124081|ref|YP_004098193.1| cystathionine beta-synthase [Intrasporangium calvum DSM 43043] gi|315588169|gb|ADU47466.1| cystathionine beta-synthase [Intrasporangium calvum DSM 43043] Length=456 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/461 (74%), Positives = 390/461 (85%), Gaps = 7/461 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGA--GTVAAKVEYLNPGGSSKDRIAVKMIEAAEAS 58 M+ A+HIS+L+G TPLV+L VV D TV AKVEY NPGGS KDRIA++MI+AAE Sbjct 1 MKYAEHISDLVGNTPLVKLGKVVEDAGVRCTVLAKVEYFNPGGSVKDRIALRMIDAAERD 60 Query 59 GQLKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPT 118 G L+PGGTIVEPTSGNTGVGLAL+AQRRGYKCVFVCPDKVS+DKR+VL AYGAEVVV PT Sbjct 61 GLLRPGGTIVEPTSGNTGVGLALIAQRRGYKCVFVCPDKVSQDKRDVLKAYGAEVVVTPT 120 Query 119 AVPPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVA 178 +V P P SYYSVSDRLV +I+GAWKP+QY NPEGP SHY TTGPEIWADT+ +VTHFVA Sbjct 121 SVAPDHPDSYYSVSDRLVAEIEGAWKPNQYYNPEGPNSHYATTGPEIWADTDHRVTHFVA 180 Query 179 GIGTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPS 238 G GTGGTI+G GRYLKEVS G VRI+ ADPEGSVYSGG+GRPYLVEGVGEDFWP AYDPS Sbjct 181 GAGTGGTISGTGRYLKEVSEGAVRIIAADPEGSVYSGGSGRPYLVEGVGEDFWPGAYDPS 240 Query 239 VPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGG 298 V DE+IAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+ AE+ DA++VVLLPD G Sbjct 241 VVDEVIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALRAAEDLPEDAVVVVLLPDSG 300 Query 299 RGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIG 358 RGYMSKIFND WM+SYGFL DGS + T+G VLR KSG +PALVHTHP+ET+RDA+ Sbjct 301 RGYMSKIFNDEWMASYGFLH---DGSDQ--TIGQVLRTKSGEMPALVHTHPNETIRDAVQ 355 Query 359 ILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIG 418 ILRE+GVSQMPVV AEPPVM+GEVAGSVSER L+ A+F GRA L D+V HM P L ++G Sbjct 356 ILREFGVSQMPVVKAEPPVMSGEVAGSVSERALMEALFTGRAHLFDSVEKHMEPGLPLVG 415 Query 419 AGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 AGE V+AA L DA++VVE+GKPVGV+TR DLLGFL++ Sbjct 416 AGEPVAAARDELEKSDAVLVVEDGKPVGVLTRADLLGFLAD 456 >gi|296128782|ref|YP_003636032.1| cystathionine beta-synthase [Cellulomonas flavigena DSM 20109] gi|296020597|gb|ADG73833.1| cystathionine beta-synthase [Cellulomonas flavigena DSM 20109] Length=468 Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/473 (74%), Positives = 393/473 (84%), Gaps = 19/473 (4%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ AQH+SEL+GGTPLVRL+SV T+ AKVEYLNPGGS KDRIA++MIEAAEASG+ Sbjct 1 MKYAQHVSELVGGTPLVRLSSVTTGLTATILAKVEYLNPGGSVKDRIALRMIEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQR+GY+CVFVCPDKVS+DKR+VL AYGAEVVV PTAV Sbjct 61 LQPGGTIVEPTSGNTGVGLALVAQRKGYRCVFVCPDKVSQDKRDVLRAYGAEVVVTPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDR+ R+ GAWKP+QYAN GPASHY +TGPEIWADT+G+VTH VAG+ Sbjct 121 PPDHPDSYYSVSDRITRETPGAWKPNQYANVNGPASHYASTGPEIWADTDGRVTHLVAGV 180 Query 181 GTGGTITGAGRYLKEVS-------GGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPA 233 GTGGTITG GR+LK+VS GGRV +VGADP GSVYSGG GRPYLVEGVGEDFWP Sbjct 181 GTGGTITGTGRFLKDVSADRPAADGGRVVVVGADPAGSVYSGGDGRPYLVEGVGEDFWPT 240 Query 234 AYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAE-------EAGP 286 AYDP+VPDEIIAVSD+DSFDMTRRLAREE +LVGGSCGMAV A L+ A EA Sbjct 241 AYDPAVPDEIIAVSDADSFDMTRRLAREEGLLVGGSCGMAVEATLRHARDLQERDPEAAA 300 Query 287 DALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVH 346 A+ VV+LPDGGRGY+SKIFND WM SYGFL S DG ++V DVLR K GALP LVH Sbjct 301 RAVYVVILPDGGRGYLSKIFNDGWMRSYGFL-SAGDG----ASVADVLRSKDGALPDLVH 355 Query 347 THPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV 406 THP+E+VRDAI ILREYGVSQMPVVGAEPPVM GEVAGSVSERELL AVF G A LAD V Sbjct 356 THPTESVRDAIEILREYGVSQMPVVGAEPPVMIGEVAGSVSERELLDAVFSGAASLADRV 415 Query 407 SAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 HM+PPL +IG+GE V AA AL DALMVV++G+PVGV+TR+DLLGFL+ Sbjct 416 DKHMAPPLPLIGSGEPVEAARAALEKADALMVVDDGRPVGVLTRHDLLGFLTH 468 >gi|84497854|ref|ZP_00996651.1| putative cystathionine beta-synthase [Janibacter sp. HTCC2649] gi|84381354|gb|EAP97237.1| putative cystathionine beta-synthase [Janibacter sp. HTCC2649] Length=458 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/461 (74%), Positives = 387/461 (84%), Gaps = 9/461 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ A+HI++L+G TPLV+LNSV A TV AKVEY+NPGGS KDRIA+KMIEAAEASG Sbjct 1 MKYAEHIADLVGNTPLVKLNSVTDGIAATVLAKVEYMNPGGSVKDRIALKMIEAAEASGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQR+GYKC+FVCPDKVSEDKRNVL AYGA+VVVCPTAV Sbjct 61 LQPGGTIVEPTSGNTGVGLALVAQRKGYKCIFVCPDKVSEDKRNVLKAYGAQVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY SDRLVR+ GAWKPDQY+NP GPASHY TTGPEIW DT+G +THFV GI Sbjct 121 SPDHPDSYYETSDRLVRETPGAWKPDQYSNPMGPASHYETTGPEIWNDTDGTLTHFVTGI 180 Query 181 GTGGTITGAGRYLKEVS----GGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYD 236 GTGGTITG GRYL+E S GGRV+I+GADPEGSVYSGG GRPYLVEGVGEDFWP AYD Sbjct 181 GTGGTITGTGRYLREQSDSREGGRVQIIGADPEGSVYSGGTGRPYLVEGVGEDFWPTAYD 240 Query 237 PSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPD 296 P V D+I+AVSD+DSFDMTRRLAREE +LVGGSCGMAVVAAL+VA++ DA++VVLLPD Sbjct 241 PKVVDQIVAVSDADSFDMTRRLAREEGLLVGGSCGMAVVAALEVAKDLPADAIVVVLLPD 300 Query 297 GGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDA 356 GRGYMSKIF+D WMSSYGF+ S D +T TVG +LR KSG +PALVHTHP+ET+RDA Sbjct 301 SGRGYMSKIFSDDWMSSYGFMHS--DAAT---TVGSILRAKSGEMPALVHTHPNETIRDA 355 Query 357 IGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRM 416 I ILREYGVSQMPVV AEPPVM GEVAGSVSERELL +F G+A L+D+V HM L + Sbjct 356 IEILREYGVSQMPVVKAEPPVMTGEVAGSVSERELLELLFVGKAHLSDSVEKHMGKGLPL 415 Query 417 IGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFL 457 +G+GE VS A L DA++V+E GKPVGV+TR DLLG L Sbjct 416 VGSGEPVSTARHELEQADAVLVIEGGKPVGVLTRADLLGHL 456 >gi|152965050|ref|YP_001360834.1| cystathionine beta-synthase [Kineococcus radiotolerans SRS30216] gi|151359567|gb|ABS02570.1| cystathionine beta-synthase [Kineococcus radiotolerans SRS30216] Length=454 Score = 657 bits (1695), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/458 (75%), Positives = 386/458 (85%), Gaps = 7/458 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR A+ + +L+GGTPLV+LN V A TV AKVEYLNPGGS KDRIA +MIEAAEA G Sbjct 1 MRYAETVVDLVGGTPLVKLNRVTEGLACTVLAKVEYLNPGGSVKDRIATRMIEAAEAEGL 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGYKCVFVCPDKV DKRNVL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYKCVFVCPDKVGADKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP SYYSVSDRLVR+I+GAWKP+QY+N GP SHY TTGPEIWADTEG++THFV G+ Sbjct 121 PPEDPQSYYSVSDRLVREIEGAWKPNQYSNVHGPRSHYETTGPEIWADTEGRITHFVTGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTITG GRYLKE G V+++GADPEGSVYSGG GRPYLVEGVGEDFWP AYDPS+P Sbjct 181 GTGGTITGTGRYLKE--QGPVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPTAYDPSIP 238 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD+DSF+MTRRLAREE +LVGGSCGMAVVAAL+ A++ GPD ++VVLLPDGGRG Sbjct 239 DEIIAVSDADSFEMTRRLAREEGLLVGGSCGMAVVAALRAAKDLGPDDVVVVLLPDGGRG 298 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+ KIFND WM+SYGFL S G TVG+VLR K+ LPALVHTHP+ETV D I I+ Sbjct 299 YLGKIFNDDWMASYGFLDSGARG-----TVGEVLRAKTTGLPALVHTHPTETVHDVIEIM 353 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQ+PVVGAEPPVMAGE+AG+V+ER LL A+F GRAK++DAVSAHM P L ++GAG Sbjct 354 REYGVSQLPVVGAEPPVMAGEIAGAVNERALLDALFTGRAKMSDAVSAHMGPALPLVGAG 413 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 + V DA +VVE+GKP GVITR+DLL +L+ Sbjct 414 QSVEDVRSVFSGADAAVVVEDGKPTGVITRHDLLAYLA 451 >gi|134097497|ref|YP_001103158.1| cystathionine beta-synthase [Saccharopolyspora erythraea NRRL 2338] gi|291004510|ref|ZP_06562483.1| cystathionine beta-synthase [Saccharopolyspora erythraea NRRL 2338] gi|133910120|emb|CAM00233.1| cystathionine beta-synthase [Saccharopolyspora erythraea NRRL 2338] Length=455 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/458 (73%), Positives = 386/458 (85%), Gaps = 5/458 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M +HI++L+G TPLVRLNS+ GA V AKVEY+NPGGS KDRIA++M+EAAEASG+ Sbjct 1 MDYVEHIADLVGNTPLVRLNSLA-KGATPVLAKVEYMNPGGSVKDRIALRMVEAAEASGE 59 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQR+GY+CVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 60 LRPGGTIVEPTSGNTGVGLAMVAQRKGYRCVFVCPDKVSEDKRNVLAAYGAEVVVCPTAV 119 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRLV +IDGAWKP+QYANP P SHY +TGPEIW TEG+VTHFVAGI Sbjct 120 PPEHPDSYYSVSDRLVTEIDGAWKPNQYANPANPESHYHSTGPEIWRQTEGRVTHFVAGI 179 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVS GRV+I+GADPEGSVYSGG GRPYLVEGVGEDFWP YD + Sbjct 180 GTGGTISGTGRYLKEVSDGRVQIIGADPEGSVYSGGVGRPYLVEGVGEDFWPDTYDRDIC 239 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 D+I+AVSD+DSF +TR LAREEA+LVGGSCGMAV AALK+AE GPD +IVVLLPDGGRG Sbjct 240 DQIVAVSDADSFHVTRDLAREEALLVGGSCGMAVAAALKIAETTGPDDVIVVLLPDGGRG 299 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y++K+FND+WM+SYGFL G +VGDVLRRK G +P LVH HP+ETV +A+ IL Sbjct 300 YLTKVFNDSWMASYGFLSPDHAG----GSVGDVLRRKDGTIPELVHVHPNETVAEAVAIL 355 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 RE+GVSQMPVV AEPPVMA EVAG+V+ER+LL A+F GRA LAD V HMSPPL IGAG Sbjct 356 REFGVSQMPVVNAEPPVMAAEVAGAVNERDLLDALFAGRANLADRVELHMSPPLPTIGAG 415 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E +S+A AL + D MV+ +GKP GV+TR D+LGF++ Sbjct 416 EEISSAMGALTNADGAMVLIDGKPAGVVTRQDVLGFIA 453 >gi|269957454|ref|YP_003327243.1| cystathionine beta-synthase [Xylanimonas cellulosilytica DSM 15894] gi|269306135|gb|ACZ31685.1| cystathionine beta-synthase [Xylanimonas cellulosilytica DSM 15894] Length=468 Score = 654 bits (1687), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/472 (73%), Positives = 393/472 (84%), Gaps = 19/472 (4%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR A+HISEL+GGTPLVRL SV + TV AKVEYLNPGGS KDRIA+KMIEAAEASG+ Sbjct 1 MRYAEHISELVGGTPLVRLTSVTAGLSATVLAKVEYLNPGGSVKDRIALKMIEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLALVAQR+GY+CVFVCPDKVS+DKR+VL AYGA V V PTAV Sbjct 61 LEPGGTIVEPTSGNTGVGLALVAQRKGYQCVFVCPDKVSKDKRDVLAAYGARVEVTPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP DP+SYYSVSDRL+R+I GAWKP+QYANP GPASHY +TGPEIW DT+G+VTHFVAG+ Sbjct 121 PPEDPSSYYSVSDRLMREIPGAWKPNQYANPNGPASHYESTGPEIWDDTDGRVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVS-------GGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPA 233 GTGGTITG GRYL +VS GGRVR+VG DP GSVYSGG GRPYLVEGVGEDFWPA Sbjct 181 GTGGTITGTGRYLHDVSGSRSEDDGGRVRVVGVDPAGSVYSGGDGRPYLVEGVGEDFWPA 240 Query 234 AYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAE-------EAGP 286 AYDP+VPDEIIAV+D++SF MTRRLAREEA+LVGGSCGMAV AAL++A+ +A Sbjct 241 AYDPAVPDEIIAVTDAESFAMTRRLAREEALLVGGSCGMAVTAALRLAQRLEDEDPQAAA 300 Query 287 DALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVH 346 A+IVVLLPD GRGYMSKIF+DAWM SYGFL +++ +T GDVLR K+G LP LVH Sbjct 301 KAVIVVLLPDSGRGYMSKIFDDAWMRSYGFL-----DASQGATAGDVLRAKAGDLPQLVH 355 Query 347 THPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV 406 HP++TV DAIG+LREYGVSQMPVV AEPPV GEVAGS++ER LL VF G+A LAD V Sbjct 356 AHPTDTVHDAIGMLREYGVSQMPVVVAEPPVKIGEVAGSLTERALLDLVFSGKAGLADPV 415 Query 407 SAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 SAHM P ++G GE + A AL D DAL+VVE+G PVGV+TR+D+LGFL+ Sbjct 416 SAHMEPRFPLVGTGEDIDAVRAALHDADALLVVEDGNPVGVLTRHDVLGFLA 467 >gi|302530131|ref|ZP_07282473.1| cystathionine beta-synthase [Streptomyces sp. AA4] gi|302439026|gb|EFL10842.1| cystathionine beta-synthase [Streptomyces sp. AA4] Length=456 Score = 642 bits (1657), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/458 (71%), Positives = 385/458 (85%), Gaps = 4/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M A+HI +L+G TPLV+LNS+ V AKVEY+NPGGS KDRIA++MIEAAEASG+ Sbjct 1 MEYAEHIVDLVGNTPLVKLNSLTRGLKPLVLAKVEYVNPGGSVKDRIALRMIEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQR+GY+CVFVCPDKVSEDKRNVL AYGA VVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLAMVAQRKGYQCVFVCPDKVSEDKRNVLRAYGARVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRLVR+I+GAWKP+QYANPE PASHY +TGPE+W T+GK+THFVAG+ Sbjct 121 APEHPDSYYNVSDRLVREIEGAWKPNQYANPENPASHYHSTGPELWRQTDGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G G++LKEVS GRV++VGADPEGSVYSGG GRPYLVEGVGEDFWP YD +V Sbjct 181 GTGGTISGTGKFLKEVSDGRVQVVGADPEGSVYSGGTGRPYLVEGVGEDFWPETYDRNVA 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 D+II +SD+ SF++TRRLA EE +LVGGSCGMAV AALK+AE D ++VVLLPDGGRG Sbjct 241 DQIIPISDAHSFEITRRLATEEGLLVGGSCGMAVAAALKLAEGLTEDDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y++K+FNDAWMSSYGFL G +TVGDVL RKSGALP+LVH+HP+ETV +A+ IL Sbjct 301 YLTKVFNDAWMSSYGFLPPDSSG----ATVGDVLTRKSGALPSLVHSHPNETVAEAVAIL 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 E+GVSQMPVV AEPPVMA EV G+V+ER+LL A+F G+A+LAD + HMSPPL IGAG Sbjct 357 SEFGVSQMPVVSAEPPVMAAEVVGAVNERDLLDALFTGKAQLADRLETHMSPPLPTIGAG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E VSAA KAL D +V+ +GKP GV+TR+DLL FL+ Sbjct 417 EQVSAAMKALEGADGALVLIDGKPAGVVTRHDLLAFLA 454 >gi|257057157|ref|YP_003134989.1| cystathionine beta-synthase [Saccharomonospora viridis DSM 43017] gi|256587029|gb|ACU98162.1| cystathionine beta-synthase [Saccharomonospora viridis DSM 43017] Length=457 Score = 637 bits (1643), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 323/458 (71%), Positives = 384/458 (84%), Gaps = 4/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M A+H+ +L+G TPLV+LN++ + AKVEY+NPGGS KDRIA++M+EAAEASG+ Sbjct 1 MDYAEHVIDLVGNTPLVKLNALAEGVEPLILAKVEYMNPGGSVKDRIALRMVEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQR+GY+CVFVCPDKVSEDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLAMVAQRKGYRCVFVCPDKVSEDKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDRL R+I+GAWKP+QYANP P SHY +TGPEIW TEGK+THFVAG+ Sbjct 121 PPEHPESYYSVSDRLAREIEGAWKPNQYANPNNPESHYHSTGPEIWRQTEGKLTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKE S GRV+++GADPEGSVYSGG GRPYLVEGVGEDFWP YD ++ Sbjct 181 GTGGTISGTGRYLKEASEGRVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPDTYDRTIA 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEII V+D++SF++TRRLAREE +LVGGSCGMAV AALK+A+ GPD +IVVLLPDGGRG Sbjct 241 DEIIPVTDAESFEITRRLAREEGLLVGGSCGMAVAAALKLAKRCGPDDVIVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+ KIFND WMSSYGFL ++ +TVGDVLRRK G++P LVHTHP+ETV +A+ IL Sbjct 301 YLGKIFNDKWMSSYGFLSP----DSQDATVGDVLRRKDGSMPDLVHTHPTETVAEAVSIL 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 RE+GVSQMPVV AEPPVMAGEV G+V+ER+LL A+F G+A L D + HMSPPL IGAG Sbjct 357 REFGVSQMPVVNAEPPVMAGEVVGAVNERDLLEALFTGKASLTDQLDKHMSPPLPTIGAG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E + AA KAL + +V+ +GKP GV+TR+DLL FLS Sbjct 417 EHIGAAMKALSEASGALVLLDGKPAGVVTRHDLLAFLS 454 >gi|300789921|ref|YP_003770212.1| cystathionine beta-synthase [Amycolatopsis mediterranei U32] gi|299799435|gb|ADJ49810.1| cystathionine beta-synthase [Amycolatopsis mediterranei U32] gi|340531592|gb|AEK46797.1| cystathionine beta-synthase [Amycolatopsis mediterranei S699] Length=456 Score = 637 bits (1643), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 322/458 (71%), Positives = 379/458 (83%), Gaps = 4/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M A+HI++L+G TPLV+LNS+ V AKVEYLNPGGS KDRIA++M+EAAEASG+ Sbjct 1 MEYAEHIADLVGNTPLVKLNSLTKGLKPLVLAKVEYLNPGGSVKDRIALRMVEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQR+GY+CVFVCPDKVSEDKRNVL AYGA VVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLAMVAQRKGYRCVFVCPDKVSEDKRNVLKAYGARVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRLVR+I+GAWKP+QYANP+ P SHY +TGPE+W TEGK+THFVAG+ Sbjct 121 APEHPDSYYNVSDRLVREIEGAWKPNQYANPQNPESHYRSTGPELWTQTEGKITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G G+YLKEVS G V++VGADPEGSVYSGG+GRPYLVEGVGEDFWP YD + Sbjct 181 GTGGTISGTGKYLKEVSDGAVQVVGADPEGSVYSGGSGRPYLVEGVGEDFWPDTYDRDIA 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEII VSD+DSF +TRRLA EE +LVGGSCGMAV AALK+AE D ++VVLLPDGGRG Sbjct 241 DEIIPVSDADSFQITRRLALEEGLLVGGSCGMAVAAALKLAERLTEDDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 YM+K+FND WMSSYGFL G +TV DVL +KSG LPALVH+HP+ETV +A+ IL Sbjct 301 YMTKVFNDTWMSSYGFLPPDSSG----ATVADVLTKKSGHLPALVHSHPNETVAEAVAIL 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 E+GVSQMPVV AEPPVMA EV G+V+ER+LL A+F G+A+LAD + HMSPPL IG G Sbjct 357 SEFGVSQMPVVSAEPPVMAAEVVGAVNERDLLDALFTGKAQLADRLEQHMSPPLPTIGGG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E V AA AL D +V+ +GKP GV+TR+DLLGFL+ Sbjct 417 EQVGAAMTALVGADGALVLVDGKPAGVLTRHDLLGFLA 454 >gi|148272051|ref|YP_001221612.1| putative cystathionine beta-synthase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147829981|emb|CAN00909.1| putative cystathionine beta-synthase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=454 Score = 633 bits (1632), Expect = 2e-179, Method: Compositional matrix adjust. Identities = 317/459 (70%), Positives = 369/459 (81%), Gaps = 5/459 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ A I +LIG TPLV+LN VV + TV KVEYLNPGGS+KDRIA ++I+AAE G+ Sbjct 1 MKYADTILDLIGNTPLVKLNKVVEGISATVLVKVEYLNPGGSAKDRIATRIIDAAERDGK 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGY+CVFV PDKV EDKRNVL AYGAE+VV PT+V Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYRCVFVLPDKVGEDKRNVLTAYGAEIVVTPTSV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYYSVSDRL R+I GA+KPDQY+NP GP SHY TTGPEIW DTEG++THFVAG+ Sbjct 121 APDHPDSYYSVSDRLAREIPGAFKPDQYSNPNGPLSHYETTGPEIWRDTEGEITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVS GRVRIVGADPEGSVYSGG GRPYLVEGVGEDFWPAAYDP V Sbjct 181 GTGGTISGVGRYLKEVSEGRVRIVGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPDVV 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DE+IA SD +SFDMT RLAREE +LVGGS GMAVV+ALK A GPD ++V+LLPDGGRG Sbjct 241 DEVIASSDQESFDMTLRLAREEGLLVGGSSGMAVVSALKAARHLGPDDVMVILLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+ KIFN+ WM SYGF +R++G Q TV DV+ K+G+LP LVH HP++T+RDAI I+ Sbjct 301 YLGKIFNEKWMQSYGF--ARVNG---QRTVADVMSAKTGSLPDLVHAHPNDTIRDAIRIM 355 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EY VSQ+PV+ AEPPV+ GEVAG+V ER LL VF GRA+L+D V P +IG Sbjct 356 TEYDVSQLPVLTAEPPVVMGEVAGAVDERSLLELVFSGRAQLSDQVGPFAGAPFGLIGVN 415 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 E V A AL DALMV + GKPVGV+TR+DLL +L++ Sbjct 416 ETVPDAWSALGSADALMVSDGGKPVGVLTRHDLLTYLTD 454 >gi|256374849|ref|YP_003098509.1| cystathionine beta-synthase [Actinosynnema mirum DSM 43827] gi|255919152|gb|ACU34663.1| cystathionine beta-synthase [Actinosynnema mirum DSM 43827] Length=456 Score = 632 bits (1630), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 323/458 (71%), Positives = 378/458 (83%), Gaps = 4/458 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M + + +L+G TPLVRLN+V V AKVEYLNPGGS KDRIA++M+EAAE SG Sbjct 1 MEYVESVVDLVGNTPLVRLNAVAEGLKPLVLAKVEYLNPGGSVKDRIALRMVEAAERSGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L PGGTIVEPTSGNTGVGLALVAQ++GYKCVFVCPDKVS DKRNVL AYGAEVVVCPTAV Sbjct 61 LGPGGTIVEPTSGNTGVGLALVAQQKGYKCVFVCPDKVSVDKRNVLKAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY+VSDRLV +I GAWKP+QYANPE PASHY TGPE+W TEG++THFVAG+ Sbjct 121 APEHPDSYYNVSDRLVAEIPGAWKPNQYANPENPASHYHGTGPELWRQTEGRITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVS GRV++VGADPEGSVYSGG+GRPYLVEGVGEDFWP AYD +V Sbjct 181 GTGGTISGTGRYLKEVSEGRVKVVGADPEGSVYSGGSGRPYLVEGVGEDFWPDAYDRTVC 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEI+AVSD+DSF++TRRLAREE +LVGGSCGMAV AAL+VAE+ GPD ++VVLLPDGGRG Sbjct 241 DEIVAVSDADSFELTRRLAREEGLLVGGSCGMAVAAALRVAEKCGPDDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+S +FND WM+ YGF+ G +TVGDVLRRK G +P LVH HP+ETV +A+ I+ Sbjct 301 YLSSVFNDQWMAQYGFMAPDSTG----ATVGDVLRRKDGTMPDLVHAHPNETVAEAVAIM 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQMPVV AEPPVMA EVAG+V+ER+LL A+F G+A LAD + +HMS L IGAG Sbjct 357 REYGVSQMPVVNAEPPVMAAEVAGAVNERDLLDALFTGKAHLADRLESHMSVKLPTIGAG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLS 458 E V AA AL D +V+++GKP GV+TR D+LGFL+ Sbjct 417 EPVGAAMTALSSADGALVLDDGKPAGVVTRQDILGFLA 454 >gi|334337936|ref|YP_004543088.1| cystathionine beta-synthase [Isoptericola variabilis 225] gi|334108304|gb|AEG45194.1| cystathionine beta-synthase [Isoptericola variabilis 225] Length=468 Score = 629 bits (1622), Expect = 3e-178, Method: Compositional matrix adjust. Identities = 336/473 (72%), Positives = 382/473 (81%), Gaps = 19/473 (4%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR A+HISEL+G TPLVRL+ V + T+ AKVEY NPGGS KDRIA+KM+EAAE SG Sbjct 1 MRYAEHISELVGRTPLVRLSRVTEGLSATILAKVEYFNPGGSVKDRIALKMVEAAEESGL 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQR+GY+CVFVCPDKVS+DKR+VL AYGA VVV PTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQRKGYECVFVCPDKVSKDKRDVLAAYGARVVVTPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 PP P SYYSVSDR+V + GAWKPDQY+NP GPASHY +TGPE+W DT+G+VTHFVAG+ Sbjct 121 PPDHPDSYYSVSDRIVAETPGAWKPDQYSNPNGPASHYESTGPEVWDDTDGRVTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVS-------GGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPA 233 GTGGTITG GRYLKEVS GG VRIVGADP GSVYSGG GRPYLVEGVGEDFWP Sbjct 181 GTGGTITGTGRYLKEVSADRAPEDGGPVRIVGADPAGSVYSGGDGRPYLVEGVGEDFWPR 240 Query 234 AYDPSVPDEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEE-------AGP 286 AYDPSVPDE+I V+D+DSF MTRRLAREE +LVGGSCGMAV AAL++A A Sbjct 241 AYDPSVPDEVIPVTDADSFAMTRRLAREEGLLVGGSCGMAVEAALRLARRLEDEDPVAAS 300 Query 287 DALIVVLLPDGGRGYMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVH 346 A+IVVLLPD GRGYMSKIF+DAWM SYGFL + + T GDVLR K+GALP LVH Sbjct 301 KAVIVVLLPDSGRGYMSKIFSDAWMRSYGFL-----DADAEITAGDVLRGKTGALPDLVH 355 Query 347 THPSETVRDAIGILREYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAV 406 THP+ETVRDAI IL EYGVSQMPVV AEPPV GEVAG+V+ERELL AVF G+A+LAD V Sbjct 356 THPNETVRDAIEILHEYGVSQMPVVVAEPPVKIGEVAGAVTERELLDAVFSGKAQLADRV 415 Query 407 SAHMSPPLRMIGAGELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 S HM+ ++G GE + A AL+ DAL+VV+ G PVGV+TR+DLLG+L+ Sbjct 416 SDHMAERFPLVGIGEGLDAVRAALQTSDALLVVDGGDPVGVLTRHDLLGYLAH 468 >gi|170780583|ref|YP_001708915.1| putative cystathionine beta-synthase [Clavibacter michiganensis subsp. sepedonicus] gi|169155151|emb|CAQ00251.1| putative cystathionine beta-synthase [Clavibacter michiganensis subsp. sepedonicus] Length=454 Score = 628 bits (1620), Expect = 5e-178, Method: Compositional matrix adjust. Identities = 315/459 (69%), Positives = 368/459 (81%), Gaps = 5/459 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ A I +LIG TPLV+LN VV + TV KVEYLNPGGS+KDRIA ++I+AAE G+ Sbjct 1 MKYADTILDLIGNTPLVKLNKVVEGISATVLVKVEYLNPGGSAKDRIATRIIDAAEREGK 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ+RGY+CVFV PDKV EDKRNVL AYGAE+VV PT+V Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQQRGYRCVFVLPDKVGEDKRNVLTAYGAEIVVTPTSV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P SYYSVSDRL R+I GA+KPDQY+NP GP SHY TTGPEIW DTEG++THFVAG+ Sbjct 121 APDHSDSYYSVSDRLAREIPGAFKPDQYSNPNGPLSHYETTGPEIWRDTEGEITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVS GRVRIVGADPEGSVYSGG GRPYLVEGVGEDFWPAAYDP V Sbjct 181 GTGGTISGVGRYLKEVSEGRVRIVGADPEGSVYSGGTGRPYLVEGVGEDFWPAAYDPDVV 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DE+IA SD +SFDMT RLAREE +LVGGS GMAVV+ALK A+ GPD ++V+LLPDGGRG Sbjct 241 DEVIASSDQESFDMTLRLAREEGLLVGGSSGMAVVSALKAAKHLGPDDVMVILLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+ KIFN+ WM SYGF +R++G Q TV DV+ K+G+LP LVH HP++T+RDAI I+ Sbjct 301 YLGKIFNERWMQSYGF--ARVNG---QRTVADVMSAKTGSLPDLVHAHPNDTIRDAIRIM 355 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 EY VSQ+PV+ AEPPV+ GEVAG+V ER LL VF GRA+L+D V +IG Sbjct 356 TEYDVSQLPVLSAEPPVVMGEVAGAVDERSLLELVFSGRAQLSDQVGPFTGDAFGLIGVN 415 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 E V A AL DALMV + GKPVGV+TR+DLL +L++ Sbjct 416 ETVPDAWSALGSADALMVSDGGKPVGVLTRHDLLTYLTD 454 >gi|330465834|ref|YP_004403577.1| cystathionine beta-synthase [Verrucosispora maris AB-18-032] gi|328808805|gb|AEB42977.1| cystathionine beta-synthase [Verrucosispora maris AB-18-032] Length=456 Score = 623 bits (1606), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 315/457 (69%), Positives = 367/457 (81%), Gaps = 4/457 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 M+ ++ ELIG TPLVRL +V TV AKVEYLNPGGS KDRIA++M+E AEA+G Sbjct 1 MQYYDNVVELIGNTPLVRLRNVAEGIQATVLAKVEYLNPGGSVKDRIALRMVEDAEAAGI 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 LKPGGTIVEPTSGNTGVGLALVAQ +GYKCVFVCPDKVS+DK++VL AYGAEVVVCPTAV Sbjct 61 LKPGGTIVEPTSGNTGVGLALVAQLKGYKCVFVCPDKVSQDKQDVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P DP SYY+VSDRL R+I GAWKP+QYANP P SHY TGPE+W TEG++THFVAG+ Sbjct 121 APEDPRSYYNVSDRLAREIPGAWKPNQYANPANPRSHYEVTGPELWKQTEGRITHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKE SGG V+++GADPEGSVYSGG GRPYLVEGVGEDFWP YD SV Sbjct 181 GTGGTISGIGRYLKEASGGTVKVIGADPEGSVYSGGTGRPYLVEGVGEDFWPETYDRSVA 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEII VSD SF+MTRRLAREE +LVGGSCGMA VAAL+VA AGPD ++VVLLPDGGRG Sbjct 241 DEIIEVSDKQSFEMTRRLAREEGLLVGGSCGMAAVAALEVARSAGPDDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+ YGF LD S + TV + L K G LP LVH HP+ETVRDA+ + Sbjct 301 YLSKIFNDTWMARYGF----LDNSGSEPTVAEALAGKPGGLPELVHVHPTETVRDAVDYM 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQ+PV+ AEPPV+ GEVAGS++ER+LL A+F G+A+L D + HM+PPL M+G G Sbjct 357 REYGVSQLPVLKAEPPVVTGEVAGSIAERDLLDALFTGQAQLHDTIERHMAPPLPMVGGG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFL 457 + VS A L DA +V+ +GKP GV+TR DLL L Sbjct 417 QPVSEAVNLLEKSDAALVLIDGKPKGVLTRQDLLAHL 453 >gi|325003215|ref|ZP_08124327.1| cystathionine beta-synthase [Pseudonocardia sp. P1] Length=455 Score = 620 bits (1600), Expect = 1e-175, Method: Compositional matrix adjust. Identities = 326/460 (71%), Positives = 375/460 (82%), Gaps = 5/460 (1%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR +H+ +L+G TPLVRL + A V AKVEYLNPGGS KDRIA++M+EAAEASG+ Sbjct 1 MRYVEHVVDLVGNTPLVRLGATAEGIAPPVLAKVEYLNPGGSVKDRIALRMVEAAEASGE 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQR+GY CVFVCPDKV EDKRNVL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLAMVAQRKGYHCVFVCPDKVGEDKRNVLQAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P SYY SDRLV +IDGAWKP+QYANP P SHY +TGPEIW T+GK+THFVAGI Sbjct 121 DPDHPDSYYRTSDRLVEEIDGAWKPNQYANPANPESHYHSTGPEIWEQTDGKITHFVAGI 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVSGG V+I+GADPEGSVYSGG GRPYLVEGVGEDFWP YD V Sbjct 181 GTGGTISGIGRYLKEVSGGAVKIIGADPEGSVYSGGTGRPYLVEGVGEDFWPTTYDRDVC 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEI+AVSD+DSF MTRRLAREEA+LVGGSCGMA VAAL+VA DA++VVLLPDGGRG Sbjct 241 DEIVAVSDTDSFHMTRRLAREEALLVGGSCGMAAVAALRVAATLPADAVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+ K+FND WM+SYGFL +E +T+GDVLRRK G++PALVH HP+ETV DA L Sbjct 301 YLGKVFNDRWMASYGFLP-----PSEGATIGDVLRRKDGSMPALVHAHPNETVADAALYL 355 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 RE+GVSQMPVV AEPPVMA EVAG+V ER+LL A+F GRA+LAD + HMSPPL +GAG Sbjct 356 REFGVSQMPVVKAEPPVMAAEVAGAVVERDLLDALFTGRAQLADRLEDHMSPPLPTLGAG 415 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSEG 460 E V A +A DA +V+ +GKP GV+TR D++GFL G Sbjct 416 ESVQDAMEAFAKADAALVLMDGKPAGVVTRSDVIGFLGNG 455 >gi|271969755|ref|YP_003343951.1| cystathionine beta-synthase [Streptosporangium roseum DSM 43021] gi|270512930|gb|ACZ91208.1| cystathionine beta-synthase [Streptosporangium roseum DSM 43021] Length=456 Score = 619 bits (1596), Expect = 4e-175, Method: Compositional matrix adjust. Identities = 314/459 (69%), Positives = 370/459 (81%), Gaps = 4/459 (0%) Query 1 MRIAQHISELIGGTPLVRLNSVVPDGAGTVAAKVEYLNPGGSSKDRIAVKMIEAAEASGQ 60 MR+ + ELIG TPLVRL+ V V AKVEY NPGGS KDRIAV+MI+AAE SG Sbjct 1 MRVHDSLVELIGNTPLVRLHKVTAGLPAQVLAKVEYFNPGGSVKDRIAVRMIDAAEKSGA 60 Query 61 LKPGGTIVEPTSGNTGVGLALVAQRRGYKCVFVCPDKVSEDKRNVLIAYGAEVVVCPTAV 120 L+PGGTIVEPTSGNTGVGLA+VAQ+RGYKC+FV PDKV++DK VL AYGAEVVVCPTAV Sbjct 61 LRPGGTIVEPTSGNTGVGLAIVAQQRGYKCLFVVPDKVAQDKIAVLRAYGAEVVVCPTAV 120 Query 121 PPHDPASYYSVSDRLVRDIDGAWKPDQYANPEGPASHYVTTGPEIWADTEGKVTHFVAGI 180 P P+SYYSVSDRL R+ AWKPDQY+NP P SHY +TGPEIW TEG++THFVAG+ Sbjct 121 SPDHPSSYYSVSDRLARETPNAWKPDQYSNPNNPDSHYHSTGPEIWEQTEGRLTHFVAGV 180 Query 181 GTGGTITGAGRYLKEVSGGRVRIVGADPEGSVYSGGAGRPYLVEGVGEDFWPAAYDPSVP 240 GTGGTI+G GRYLKEVS GRV+I+GADPEGSVYSGG+GRPYLVEGVGED WPA YD ++ Sbjct 181 GTGGTISGIGRYLKEVSDGRVKIIGADPEGSVYSGGSGRPYLVEGVGEDIWPATYDTTIC 240 Query 241 DEIIAVSDSDSFDMTRRLAREEAMLVGGSCGMAVVAALKVAEEAGPDALIVVLLPDGGRG 300 DEIIAVSD DSF MTRRLAREEA+LVGGSCGMA VAAL+VA++AGPD ++VVLLPDGGRG Sbjct 241 DEIIAVSDKDSFGMTRRLAREEALLVGGSCGMAAVAALRVAKQAGPDDVVVVLLPDGGRG 300 Query 301 YMSKIFNDAWMSSYGFLRSRLDGSTEQSTVGDVLRRKSGALPALVHTHPSETVRDAIGIL 360 Y+SKIFND WM+ YGFL + S+++ V DVL RK +P VHTHP E+V AI I+ Sbjct 301 YLSKIFNDDWMADYGFLTT----SSDEGLVKDVLTRKGSGMPEFVHTHPHESVDTAISIM 356 Query 361 REYGVSQMPVVGAEPPVMAGEVAGSVSERELLSAVFEGRAKLADAVSAHMSPPLRMIGAG 420 REYGVSQ+PV+ EPPVMA EV GS+ ER+LL A++ GR + D ++ HMS PL MIGAG Sbjct 357 REYGVSQLPVMKEEPPVMAAEVVGSILERDLLDALYRGRVRPNDPLADHMSQPLPMIGAG 416 Query 421 ELVSAAGKALRDWDALMVVEEGKPVGVITRYDLLGFLSE 459 E VS A +AL DA +V+++GKPVG++TR DLL FL+ Sbjct 417 EPVSIAVEALEKADAAVVLDDGKPVGLVTRQDLLAFLAN 455 Lambda K H 0.316 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 976493849394 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40