BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1093 Length=426 Score E Sequences producing significant alignments: (Bits) Value gi|345461997|ref|YP_177787.2| serine hydroxymethyltransferase [M... 856 0.0 gi|148660879|ref|YP_001282402.1| serine hydroxymethyltransferase... 855 0.0 gi|15840532|ref|NP_335569.1| serine hydroxymethyltransferase [My... 855 0.0 gi|339294088|gb|AEJ46199.1| serine hydroxymethyltransferase [Myc... 854 0.0 gi|229598008|pdb|3H7F|A Chain A, Crystal Structure Of Serine Hyd... 853 0.0 gi|340626107|ref|YP_004744559.1| putative serine hydroxymethyltr... 852 0.0 gi|289744837|ref|ZP_06504215.1| serine hydroxymethyltransferase ... 851 0.0 gi|298524589|ref|ZP_07011998.1| serine hydroxymethyltransferase ... 824 0.0 gi|183984346|ref|YP_001852637.1| serine hydroxymethyltransferase... 798 0.0 gi|342861682|ref|ZP_08718328.1| serine hydroxymethyltransferase ... 797 0.0 gi|118616078|ref|YP_904410.1| serine hydroxymethyltransferase [M... 795 0.0 gi|240171111|ref|ZP_04749770.1| serine hydroxymethyltransferase ... 792 0.0 gi|254819719|ref|ZP_05224720.1| serine hydroxymethyltransferase ... 787 0.0 gi|15828055|ref|NP_302318.1| serine hydroxymethyltransferase [My... 781 0.0 gi|118465701|ref|YP_880461.1| serine hydroxymethyltransferase [M... 770 0.0 gi|226730011|sp|A0QC23.2|GLYA_MYCA1 RecName: Full=Serine hydroxy... 769 0.0 gi|296169960|ref|ZP_06851567.1| glycine hydroxymethyltransferase... 768 0.0 gi|254774098|ref|ZP_05215614.1| serine hydroxymethyltransferase ... 768 0.0 gi|336458710|gb|EGO37670.1| glycine/serine hydroxymethyltransfer... 767 0.0 gi|41408797|ref|NP_961633.1| serine hydroxymethyltransferase [My... 764 0.0 gi|333989679|ref|YP_004522293.1| serine hydroxymethyltransferase... 741 0.0 gi|333921067|ref|YP_004494648.1| serine hydroxymethyltransferase... 706 0.0 gi|326381839|ref|ZP_08203532.1| serine hydroxymethyltransferase ... 703 0.0 gi|343925103|ref|ZP_08764635.1| serine hydroxymethyltransferase ... 701 0.0 gi|262201618|ref|YP_003272826.1| glycine hydroxymethyltransferas... 694 0.0 gi|312138744|ref|YP_004006080.1| glycine hydroxymethyltransferas... 669 0.0 gi|111022822|ref|YP_705794.1| serine hydroxymethyltransferase [R... 669 0.0 gi|226365330|ref|YP_002783113.1| serine hydroxymethyltransferase... 665 0.0 gi|161485985|ref|NP_737668.2| serine hydroxymethyltransferase [C... 664 0.0 gi|296140813|ref|YP_003648056.1| glycine hydroxymethyltransferas... 662 0.0 gi|213965536|ref|ZP_03393731.1| serine hydroxymethyltransferase ... 661 0.0 gi|23492896|dbj|BAC17868.1| serine hydroxymethyltransferase [Cor... 661 0.0 gi|226307739|ref|YP_002767699.1| serine hydroxymethyltransferase... 660 0.0 gi|54026787|ref|YP_121029.1| serine hydroxymethyltransferase [No... 660 0.0 gi|300781596|ref|ZP_07091450.1| glycine hydroxymethyltransferase... 657 0.0 gi|225022970|ref|ZP_03712162.1| hypothetical protein CORMATOL_03... 653 0.0 gi|19552219|ref|NP_600221.1| serine hydroxymethyltransferase [Co... 652 0.0 gi|306835721|ref|ZP_07468727.1| glycine hydroxymethyltransferase... 652 0.0 gi|319950195|ref|ZP_08024122.1| serine hydroxymethyltransferase ... 652 0.0 gi|305682105|ref|ZP_07404909.1| glycine hydroxymethyltransferase... 651 0.0 gi|227501563|ref|ZP_03931612.1| serine hydroxymethyltransferase ... 650 0.0 gi|332669649|ref|YP_004452657.1| glycine hydroxymethyltransferas... 647 0.0 gi|269796075|ref|YP_003315530.1| serine hydroxymethyltransferase... 646 0.0 gi|300858146|ref|YP_003783129.1| serine hydroxymethyltransferase... 646 0.0 gi|340794900|ref|YP_004760363.1| serine hydroxymethyltransferase... 646 0.0 gi|269955562|ref|YP_003325351.1| glycine hydroxymethyltransferas... 645 0.0 gi|227504086|ref|ZP_03934135.1| serine hydroxymethyltransferase ... 644 0.0 gi|260907101|ref|ZP_05915423.1| serine hydroxymethyltransferase ... 644 0.0 gi|334696511|gb|AEG81308.1| serine hydroxymethyltransferase [Cor... 644 0.0 gi|337290398|ref|YP_004629419.1| serine hydroxymethyltransferase... 644 0.0 >gi|345461997|ref|YP_177787.2| serine hydroxymethyltransferase [Mycobacterium tuberculosis H37Rv] Length=438 Score = 856 bits (2212), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 13 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 72 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 73 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 132 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 133 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 192 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 193 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 252 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 253 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 312 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 313 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 372 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 373 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 432 Query 421 WSLVGR 426 WSLVGR Sbjct 433 WSLVGR 438 >gi|148660879|ref|YP_001282402.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis H37Ra] gi|167969226|ref|ZP_02551503.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis H37Ra] gi|307083642|ref|ZP_07492755.1| serine hydroxymethyltransferase 1 glyA1 [Mycobacterium tuberculosis SUMu012] gi|6685483|sp|O53441.1|GLYA1_MYCTU RecName: Full=Serine hydroxymethyltransferase 1; Short=SHMT 1; Short=Serine methylase 1 gi|41353649|emb|CAE55360.1| Probable Serine hydroxymethyltransferase 1 glyA1 [Mycobacterium tuberculosis H37Rv] gi|148505031|gb|ABQ72840.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis H37Ra] gi|308366639|gb|EFP55490.1| serine hydroxymethyltransferase 1 glyA1 [Mycobacterium tuberculosis SUMu012] Length=426 Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 Query 421 WSLVGR 426 WSLVGR Sbjct 421 WSLVGR 426 >gi|15840532|ref|NP_335569.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis CDC1551] gi|31792286|ref|NP_854779.1| serine hydroxymethyltransferase [Mycobacterium bovis AF2122/97] gi|121637024|ref|YP_977247.1| serine hydroxymethyltransferase [Mycobacterium bovis BCG str. Pasteur 1173P2] 62 more sequence titles Length=426 Score = 855 bits (2208), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/426 (99%), Positives = 425/426 (99%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENF PRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 Query 421 WSLVGR 426 WSLVGR Sbjct 421 WSLVGR 426 >gi|339294088|gb|AEJ46199.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis CCDC5079] gi|339297728|gb|AEJ49838.1| serine hydroxymethyltransferase [Mycobacterium tuberculosis CCDC5180] Length=438 Score = 854 bits (2207), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/426 (99%), Positives = 425/426 (99%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENF PRAVLQAQGSVLTNKYAEGLPGRR Sbjct 13 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRR 72 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 73 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 132 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 133 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 192 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 193 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 252 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 253 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 312 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 313 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 372 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 373 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 432 Query 421 WSLVGR 426 WSLVGR Sbjct 433 WSLVGR 438 >gi|229598008|pdb|3H7F|A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Mycobacterium Tuberculosis gi|229598009|pdb|3H7F|B Chain B, Crystal Structure Of Serine Hydroxymethyltransferase From Mycobacterium Tuberculosis Length=447 Score = 853 bits (2204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/426 (99%), Positives = 425/426 (99%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 22 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 81 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 82 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 141 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 142 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 201 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVH TLGGGRSGLIVGK Sbjct 202 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHXTLGGGRSGLIVGK 261 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 262 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 321 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 322 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 381 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 382 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 441 Query 421 WSLVGR 426 WSLVGR Sbjct 442 WSLVGR 447 >gi|340626107|ref|YP_004744559.1| putative serine hydroxymethyltransferase 1 glyA1 [Mycobacterium canettii CIPT 140010059] gi|340004297|emb|CCC43438.1| putative serine hydroxymethyltransferase 1 glyA1 [Mycobacterium canettii CIPT 140010059] Length=426 Score = 852 bits (2202), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/426 (99%), Positives = 424/426 (99%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENF PRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVS LKDRATRLARAFPLYDGLEE Sbjct 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSVLKDRATRLARAFPLYDGLEE 420 Query 421 WSLVGR 426 WSLVGR Sbjct 421 WSLVGR 426 >gi|289744837|ref|ZP_06504215.1| serine hydroxymethyltransferase 1 [Mycobacterium tuberculosis 02_1987] gi|289685365|gb|EFD52853.1| serine hydroxymethyltransferase 1 [Mycobacterium tuberculosis 02_1987] Length=426 Score = 851 bits (2199), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/426 (99%), Positives = 424/426 (99%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENF PRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK Sbjct 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 QQYAKAINSAVFPGQQG PLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP Sbjct 241 QQYAKAINSAVFPGQQGDPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE Sbjct 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 Query 421 WSLVGR 426 WSLVGR Sbjct 421 WSLVGR 426 >gi|298524589|ref|ZP_07011998.1| serine hydroxymethyltransferase 1 [Mycobacterium tuberculosis 94_M4241A] gi|298494383|gb|EFI29677.1| serine hydroxymethyltransferase 1 [Mycobacterium tuberculosis 94_M4241A] Length=411 Score = 824 bits (2128), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/411 (99%), Positives = 410/411 (99%), Gaps = 0/411 (0%) Query 16 LAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGGCEHVDVVENLA 75 +AKELGRQRDTLEMIASENF PRAVLQAQGSVLTNKYAEGLPGRRYYGGCEHVDVVENLA Sbjct 1 MAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRRYYGGCEHVDVVENLA 60 Query 76 RDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGK 135 RDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGK Sbjct 61 RDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGK 120 Query 136 LYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVGAKL 195 LYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVGAKL Sbjct 121 LYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVGAKL 180 Query 196 LVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVFPGQ 255 LVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVFPGQ Sbjct 181 LVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVFPGQ 240 Query 256 QGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTD 315 QGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTD Sbjct 241 QGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTD 300 Query 316 VHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFG 375 VHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFG Sbjct 301 VHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFG 360 Query 376 DTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLVGR 426 DTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLVGR Sbjct 361 DTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLVGR 411 >gi|183984346|ref|YP_001852637.1| serine hydroxymethyltransferase 1 GlyA1 [Mycobacterium marinum M] gi|183177672|gb|ACC42782.1| serine hydroxymethyltransferase 1 GlyA1 [Mycobacterium marinum M] Length=426 Score = 798 bits (2060), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/426 (92%), Positives = 407/426 (96%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 M APLAEVDPDIA LL KELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MEAPLAEVDPDIAALLGKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGA+L VDMAHFAGLVAAGLHPSPVPHADVVSTT+HKTLGGGRSG+I+GK Sbjct 181 FAAFRSIADEVGAQLFVDMAHFAGLVAAGLHPSPVPHADVVSTTIHKTLGGGRSGMILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q++AKAINSAVFPGQQGGPLMHVIAGKAVALKIA TPEFADRQRRTL+GARI+ADRLMA Sbjct 241 QEFAKAINSAVFPGQQGGPLMHVIAGKAVALKIAGTPEFADRQRRTLAGARIVADRLMAS 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHE GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEAGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EF+EVAD+IA LA G S DV+AL+ R TRLAR FPLY+GLEE Sbjct 361 GLRIGTPALATRGFGDAEFSEVADVIAGVLAAGRSADVAALRARVTRLARDFPLYEGLEE 420 Query 421 WSLVGR 426 W+LV R Sbjct 421 WNLVDR 426 >gi|342861682|ref|ZP_08718328.1| serine hydroxymethyltransferase [Mycobacterium colombiense CECT 3035] gi|342130816|gb|EGT84112.1| serine hydroxymethyltransferase [Mycobacterium colombiense CECT 3035] Length=426 Score = 797 bits (2059), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/426 (91%), Positives = 412/426 (97%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA+VDPDIAELL KELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLADVDPDIAELLGKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEFVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLYENGFYGVDP THL+DMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMKLNFSGKLYENGFYGVDPTTHLVDMDAVRAQALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKL VDMAHFAGLVAAGLHPSPVPHAD+VSTT+HKTLGGGRSG+I+GK Sbjct 181 FAAFRSIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADIVSTTIHKTLGGGRSGMILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAKA+NSAVFPGQQGGPLMHVIAGKAVALKIA+TPEF +RQ+RTLSGARI+ADRL+A Sbjct 241 QEYAKAVNSAVFPGQQGGPLMHVIAGKAVALKIASTPEFVERQQRTLSGARILADRLLAA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLR+SPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRNSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EF+EVAD+IATALA GSS DV+ L+ R TRLA+ FPLY+GLE+ Sbjct 361 GLRIGTPALATRGFGDAEFSEVADVIATALAAGSSADVAGLRQRVTRLAQEFPLYEGLED 420 Query 421 WSLVGR 426 W+LVGR Sbjct 421 WALVGR 426 >gi|118616078|ref|YP_904410.1| serine hydroxymethyltransferase [Mycobacterium ulcerans Agy99] gi|118568188|gb|ABL02939.1| serine hydroxymethyltransferase 1 GlyA1 [Mycobacterium ulcerans Agy99] Length=426 Score = 795 bits (2054), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/426 (92%), Positives = 407/426 (96%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 M APLAEVDPDIA LL KELGRQRDTLEMIASENFVPRAVLQ QGSVLTNKYAEGLPGRR Sbjct 1 MEAPLAEVDPDIAALLGKELGRQRDTLEMIASENFVPRAVLQVQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVEN+ARDRAKALFGA+FA+VQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENIARDRAKALFGADFADVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGA+L VDMAHFAGLVAAGLHPSPVPHADVVSTT+HKTLGGGRSG+I+GK Sbjct 181 FAAFRSIADEVGAQLFVDMAHFAGLVAAGLHPSPVPHADVVSTTIHKTLGGGRSGMILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q++AKAINSAVFPGQQGGPLMHVIAGKAVALKIA TPEFADRQRRTL+GARI+ADRLMA Sbjct 241 QEFAKAINSAVFPGQQGGPLMHVIAGKAVALKIAGTPEFADRQRRTLAGARIVADRLMAS 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHE GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEAGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EF+EVAD+IA ALA G S DV+AL+ R TRLAR FPLY+GLEE Sbjct 361 GLRIGTPALATRGFGDAEFSEVADVIAGALAAGRSADVAALRARVTRLARDFPLYEGLEE 420 Query 421 WSLVGR 426 W+LV R Sbjct 421 WNLVDR 426 >gi|240171111|ref|ZP_04749770.1| serine hydroxymethyltransferase [Mycobacterium kansasii ATCC 12478] Length=426 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/426 (92%), Positives = 408/426 (96%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLAEVDP+IAELL KELGRQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLAEVDPEIAELLGKELGRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYENGFYGVDP THLIDMD VRA ALEFRPKVIIAGWSAYPR+LD Sbjct 121 GGHLTHGMRLNFSGKLYENGFYGVDPTTHLIDMDVVRAKALEFRPKVIIAGWSAYPRILD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFR+IADEV AKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSG+++GK Sbjct 181 FAAFRAIADEVDAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGMVLGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARI+A+RL+ Sbjct 241 QEYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARILAERLLGD 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLR+SPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRNSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EF+EVAD+IATALA GS+ DV AL R TRLAR FPLY GLE+ Sbjct 361 GLRIGTPALATRGFGDAEFSEVADVIATALADGSAADVPALHARVTRLAREFPLYAGLED 420 Query 421 WSLVGR 426 WSL GR Sbjct 421 WSLAGR 426 >gi|254819719|ref|ZP_05224720.1| serine hydroxymethyltransferase [Mycobacterium intracellulare ATCC 13950] Length=426 Score = 787 bits (2033), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/426 (90%), Positives = 408/426 (96%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MS PLAEVDPDIA LL +ELGRQRD LEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSVPLAEVDPDIAGLLGQELGRQRDMLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLYENGFYGVDP THL+DMDAVRA ALEFRPKVIIAGWSAYPR+LD Sbjct 121 GGHLTHGMKLNFSGKLYENGFYGVDPTTHLVDMDAVRAKALEFRPKVIIAGWSAYPRILD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEV AKL VDMAHFAGLVAAGLHPSPVPHAD+VSTT+HKTLGGGRSG+I+GK Sbjct 181 FAAFASIADEVDAKLWVDMAHFAGLVAAGLHPSPVPHADIVSTTIHKTLGGGRSGMILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAKAINSAVFPGQQGGPLMHVIAGKAVALKIA+TPEF +RQ+RTLSGARI+ADRL+A Sbjct 241 QEYAKAINSAVFPGQQGGPLMHVIAGKAVALKIASTPEFVERQQRTLSGARILADRLLAA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLR+SPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRNSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EF+EVAD+IATALA GSS DV+ L+ R TRLA+ FPLYDGLE+ Sbjct 361 GLRIGTPALATRGFGDAEFSEVADVIATALAAGSSADVAGLRQRVTRLAQEFPLYDGLED 420 Query 421 WSLVGR 426 W+LVGR Sbjct 421 WALVGR 426 >gi|15828055|ref|NP_302318.1| serine hydroxymethyltransferase [Mycobacterium leprae TN] gi|221230532|ref|YP_002503948.1| serine hydroxymethyltransferase [Mycobacterium leprae Br4923] gi|6919898|sp|Q9X794.1|GLYA_MYCLE RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase gi|254798966|sp|B8ZSH2.1|GLYA_MYCLB RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase gi|4539107|emb|CAB39828.1| putative serine hydroxymethyltransferase [Mycobacterium leprae] gi|13093608|emb|CAC30908.1| serine hydroxymethyltransferase [Mycobacterium leprae] gi|219933639|emb|CAR72050.1| serine hydroxymethyltransferase [Mycobacterium leprae Br4923] Length=426 Score = 781 bits (2018), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/426 (90%), Positives = 400/426 (94%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 M APLAEVDPDIAELL KELGRQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEGLPGRR Sbjct 1 MVAPLAEVDPDIAELLGKELGRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YY GCEHVDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALMSPGERLLGLDLAN Sbjct 61 YYDGCEHVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYE GFYGVD THLIDMDAVRA ALEFRPKV+IAGWSAYPR+LD Sbjct 121 GGHLTHGMRLNFSGKLYETGFYGVDATTHLIDMDAVRAKALEFRPKVLIAGWSAYPRILD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKL VDMAHFAGLVA GLHPSPVPHADVVSTTVHKTLGGGRSGLI+GK Sbjct 181 FAAFRSIADEVGAKLWVDMAHFAGLVAVGLHPSPVPHADVVSTTVHKTLGGGRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q++A AINSAVFPGQQGGPLMHVIAGKAVALKIA TPEF DRQ+RTL+GARI+ADRL A Sbjct 241 QEFATAINSAVFPGQQGGPLMHVIAGKAVALKIATTPEFTDRQQRTLAGARILADRLTAA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DV KAGVSVVSGGTDVHLVLVDLR+SP DGQAAEDLLHEVGITVNRN VPNDPRPPMVTS Sbjct 301 DVTKAGVSVVSGGTDVHLVLVDLRNSPFDGQAAEDLLHEVGITVNRNVVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFG+ EFTEVADIIAT L TG SVDV+AL+ + TRLAR FPLY GLE+ Sbjct 361 GLRIGTPALATRGFGEAEFTEVADIIATVLTTGGSVDVAALRQQVTRLARDFPLYGGLED 420 Query 421 WSLVGR 426 WSL GR Sbjct 421 WSLAGR 426 >gi|118465701|ref|YP_880461.1| serine hydroxymethyltransferase [Mycobacterium avium 104] gi|118166988|gb|ABK67885.1| serine hydroxymethyltransferase [Mycobacterium avium 104] Length=443 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/426 (89%), Positives = 403/426 (95%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA++DPDIA LL +ELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 18 MSAPLADIDPDIAGLLGQELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 77 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 78 YYGGCEYVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 137 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLY+ GFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 138 GGHLTHGMKLNFSGKLYDVGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 197 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 198 FAAFASIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 257 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIA KAVALKIA T EFADRQRRTLSGARI+A+RL Sbjct 258 QEYAKSINSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFADRQRRTLSGARILAERLSGA 317 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+S LDGQAAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 318 DVAAAGVSVVSGGTDVHLVLVDLRNSELDGQAAEDLLHEIGITVNRNAVPNDPRPPMVTS 377 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFGD EF+EVAD+IATALA G D++AL+DR TRLAR FPLY+GLE+ Sbjct 378 GLRVGTPALATRGFGDAEFSEVADVIATALAGGRGADLAALRDRVTRLARDFPLYEGLED 437 Query 421 WSLVGR 426 W+LVGR Sbjct 438 WALVGR 443 >gi|226730011|sp|A0QC23.2|GLYA_MYCA1 RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase Length=426 Score = 769 bits (1987), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/426 (89%), Positives = 403/426 (95%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA++DPDIA LL +ELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLADIDPDIAGLLGQELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLY+ GFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMKLNFSGKLYDVGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 181 FAAFASIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIA KAVALKIA T EFADRQRRTLSGARI+A+RL Sbjct 241 QEYAKSINSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFADRQRRTLSGARILAERLSGA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+S LDGQAAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAAAGVSVVSGGTDVHLVLVDLRNSELDGQAAEDLLHEIGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFGD EF+EVAD+IATALA G D++AL+DR TRLAR FPLY+GLE+ Sbjct 361 GLRVGTPALATRGFGDAEFSEVADVIATALAGGRGADLAALRDRVTRLARDFPLYEGLED 420 Query 421 WSLVGR 426 W+LVGR Sbjct 421 WALVGR 426 >gi|296169960|ref|ZP_06851567.1| glycine hydroxymethyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895364|gb|EFG75070.1| glycine hydroxymethyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=426 Score = 768 bits (1983), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/426 (90%), Positives = 407/426 (96%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSA LA+VDPDIAELL KELGRQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSASLADVDPDIAELLGKELGRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLYE GFYGVDP THL+DMDAVRA ALEFRP+VIIAGWSAYPR+LD Sbjct 121 GGHLTHGMKLNFSGKLYETGFYGVDPTTHLVDMDAVRARALEFRPQVIIAGWSAYPRILD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEV AKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 181 FAAFASIADEVDAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIAGKAVALKIA TPEFADRQ+RTLSGARIIADRL AP Sbjct 241 QEYAKSINSAVFPGQQGGPLMHVIAGKAVALKIAGTPEFADRQQRTLSGARIIADRLTAP 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+SPLDG+AAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAHAGVSVVSGGTDVHLVLVDLRNSPLDGKAAEDLLHEIGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFGD EFTEVAD+IATALA G++ D+S+L+ R TRLAR FPLY+GLEE Sbjct 361 GLRVGTPALATRGFGDAEFTEVADVIATALAAGTAADLSSLRQRVTRLARDFPLYEGLEE 420 Query 421 WSLVGR 426 W+LV R Sbjct 421 WTLVDR 426 >gi|254774098|ref|ZP_05215614.1| serine hydroxymethyltransferase [Mycobacterium avium subsp. avium ATCC 25291] Length=426 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/426 (89%), Positives = 402/426 (95%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA++DPDIA LL +ELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLADIDPDIAGLLGQELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALFGA+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLY+ GFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMKLNFSGKLYDVGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEVGAKL VDMAHFAG VAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 181 FAAFASIADEVGAKLWVDMAHFAGPVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIA KAVALKIA T EFADRQRRTLSGARI+A+RL Sbjct 241 QEYAKSINSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFADRQRRTLSGARILAERLSGA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+S LDGQAAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAAAGVSVVSGGTDVHLVLVDLRNSELDGQAAEDLLHEIGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFGD EF+EVAD+IATALA G D++AL+DR TRLAR FPLY+GLE+ Sbjct 361 GLRVGTPALATRGFGDAEFSEVADVIATALAGGRGADLAALRDRVTRLARDFPLYEGLED 420 Query 421 WSLVGR 426 WSLVGR Sbjct 421 WSLVGR 426 >gi|336458710|gb|EGO37670.1| glycine/serine hydroxymethyltransferase [Mycobacterium avium subsp. paratuberculosis S397] Length=426 Score = 767 bits (1980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/426 (89%), Positives = 402/426 (95%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA++DPDIA LL +ELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLADIDPDIAGLLGQELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALF A+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFDADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLY+ GFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMKLNFSGKLYDVGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 181 FAAFASIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIA KAVALKIA T EFADRQRRTLSGARI+A+RL Sbjct 241 QEYAKSINSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFADRQRRTLSGARILAERLSGA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+S LDGQAAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAAAGVSVVSGGTDVHLVLVDLRNSELDGQAAEDLLHEIGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFGD EF+EVAD+IATALA G D++AL+DR TRLAR FPLY+GLE+ Sbjct 361 GLRVGTPALATRGFGDAEFSEVADVIATALAGGRGADLAALRDRVTRLARDFPLYEGLED 420 Query 421 WSLVGR 426 W+LVGR Sbjct 421 WALVGR 426 >gi|41408797|ref|NP_961633.1| serine hydroxymethyltransferase [Mycobacterium avium subsp. paratuberculosis K-10] gi|61213512|sp|Q73WG1.1|GLYA_MYCPA RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase gi|41397156|gb|AAS05016.1| GlyA [Mycobacterium avium subsp. paratuberculosis K-10] Length=426 Score = 764 bits (1972), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/426 (89%), Positives = 401/426 (95%), Gaps = 0/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MSAPLA++DPDIA LL +ELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR Sbjct 1 MSAPLADIDPDIAGLLGQELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDVVEN+ARDRAKALF A+FANVQPHSGAQANAAVLHALM+PGERLLGLDLAN Sbjct 61 YYGGCEYVDVVENIARDRAKALFDADFANVQPHSGAQANAAVLHALMTPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSGKLY+ GFYGVDP THLIDMDAVRA ALEFRPKVIIAGWSAYPRVLD Sbjct 121 GGHLTHGMKLNFSGKLYDVGFYGVDPTTHLIDMDAVRAKALEFRPKVIIAGWSAYPRVLD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAF SIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 181 FAAFASIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q+YAK+INSAVFPGQQGGPLMHVIA KAVALKIA T EFADRQRRTLSGARI+A+RL Sbjct 241 QEYAKSINSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFADRQRRTLSGARILAERLSGA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AGVSVVSGGTDVHLVLVDLR+S LDGQAAEDLLHE+GITVNRNAVPNDPRPPMVTS Sbjct 301 DVAAAGVSVVSGGTDVHLVLVDLRNSELDGQAAEDLLHEIGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALATRGFG EF+EVAD+IATALA G D++AL+DR TRLAR FPLY+GLE+ Sbjct 361 GLRVGTPALATRGFGGAEFSEVADVIATALAGGRGADLAALRDRVTRLARDFPLYEGLED 420 Query 421 WSLVGR 426 W+LVGR Sbjct 421 WALVGR 426 >gi|333989679|ref|YP_004522293.1| serine hydroxymethyltransferase 1 GlyA1 [Mycobacterium sp. JDM601] gi|333485647|gb|AEF35039.1| serine hydroxymethyltransferase 1 GlyA1 [Mycobacterium sp. JDM601] Length=424 Score = 741 bits (1912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/423 (88%), Positives = 389/423 (92%), Gaps = 0/423 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 MS PLAE+DPDIAELL KELGRQRDTLEMIASENFVPRAVLQA GSVLTNKYAEGLPGRR Sbjct 1 MSTPLAELDPDIAELLGKELGRQRDTLEMIASENFVPRAVLQAHGSVLTNKYAEGLPGRR 60 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVEN+ARDRAK LF AEFANVQPHSGAQANAAVL ALM PGERLLGLDLAN Sbjct 61 YYGGCEHVDVVENIARDRAKELFDAEFANVQPHSGAQANAAVLQALMEPGERLLGLDLAN 120 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYEN FYGVDP TH +DMD VRA ALEF+PKVIIAGWSAYPR+LD Sbjct 121 GGHLTHGMRLNFSGKLYENAFYGVDPVTHRVDMDVVRAQALEFKPKVIIAGWSAYPRILD 180 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 F AF +IA EV A L VDMAHFAGLVAAGLHPSPVPHA VVSTTVHKTLGG RSGLIVGK Sbjct 181 FEAFAAIAAEVDATLWVDMAHFAGLVAAGLHPSPVPHAQVVSTTVHKTLGGPRSGLIVGK 240 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 +++AK INSAVFPGQQGGPLMHVIA KAVALKIA TPEFA+RQ+R LSGARIIA+RL+A Sbjct 241 KEFAKQINSAVFPGQQGGPLMHVIAAKAVALKIAGTPEFAERQQRVLSGARIIAERLLAA 300 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQ AEDLLHEVGITVNRNAVPNDPRPPMVTS Sbjct 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQMAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLR+GTPALA RGFGDTEFTEVADIIATALA GS D+SAL+ R T+LA+ FPLYDGLE+ Sbjct 361 GLRVGTPALAARGFGDTEFTEVADIIATALAAGSGADISALRSRVTKLAQDFPLYDGLED 420 Query 421 WSL 423 W L Sbjct 421 WKL 423 >gi|333921067|ref|YP_004494648.1| serine hydroxymethyltransferase [Amycolicicoccus subflavus DQS3-9A1] gi|333483288|gb|AEF41848.1| Serine hydroxymethyltransferase [Amycolicicoccus subflavus DQS3-9A1] Length=433 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/425 (83%), Positives = 382/425 (90%), Gaps = 2/425 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 +APLAE+DPD+A +A EL RQR+TLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRR Sbjct 11 FTAPLAELDPDVAAAMAGELARQRETLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRR 70 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVENLARDRAK+LFGA+FANVQPH+GAQANAAVLHA+M PGERLLGLDLA+ Sbjct 71 YYGGCEHVDVVENLARDRAKSLFGADFANVQPHAGAQANAAVLHAMMKPGERLLGLDLAH 130 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYE GFYGVDP T IDMDAVRA ALEFRPKVI+AGWSAYPR D Sbjct 131 GGHLTHGMRLNFSGKLYEVGFYGVDPQTFRIDMDAVRAKALEFRPKVIVAGWSAYPRQQD 190 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFR+IADEVGA L VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+GK Sbjct 191 FAAFRAIADEVGAHLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLIIGK 250 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q++AK INSAVFPGQQGGPLMH IA KAVALKIA T EF DRQ+RTLSGA+IIADRL + Sbjct 251 QEWAKPINSAVFPGQQGGPLMHAIAAKAVALKIAGTDEFRDRQQRTLSGAKIIADRLTST 310 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA GV+V++GGTDVHLVLVDLRDS LDG+ AEDLLHE GITVNRNAVP DPRPPMVTS Sbjct 311 DVAGKGVTVLTGGTDVHLVLVDLRDSELDGKQAEDLLHEAGITVNRNAVPFDPRPPMVTS 370 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGT ALATRGFGD+EF +VADIIA AL TG+ ++S L+D + LAR FPLY+GLE+ Sbjct 371 GLRIGTAALATRGFGDSEFEKVADIIAAAL-TGAR-EISTLRDEVSALARDFPLYEGLED 428 Query 421 WSLVG 425 W L+G Sbjct 429 WRLLG 433 >gi|326381839|ref|ZP_08203532.1| serine hydroxymethyltransferase [Gordonia neofelifaecis NRRL B-59395] gi|326199265|gb|EGD56446.1| serine hydroxymethyltransferase [Gordonia neofelifaecis NRRL B-59395] Length=429 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/424 (82%), Positives = 377/424 (89%), Gaps = 0/424 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 S LA++DPD+A ++ EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRR Sbjct 4 FSQSLADLDPDVAAAMSGELSRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRR 63 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDVVE++ARDRAKALFGA+FANVQPH+GAQANAAVL ALM PGE LLGLDLA+ Sbjct 64 YYGGCEHVDVVEDIARDRAKALFGADFANVQPHAGAQANAAVLQALMEPGETLLGLDLAH 123 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGMRLNFSGKLYEN FYGV +DMD VR AL+ +PKVI+AGWSAYPR LD Sbjct 124 GGHLTHGMRLNFSGKLYENAFYGVSKEDFRVDMDEVRKIALDTKPKVIVAGWSAYPRTLD 183 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFR IADEVGA L VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+ K Sbjct 184 FAAFREIADEVGAHLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILAK 243 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 Q++AK +NSAVFPGQQGGPLMHVIA KAVALKIAA+ EFA+RQRRTLSGA+I+A+RLMA Sbjct 244 QEWAKKLNSAVFPGQQGGPLMHVIAAKAVALKIAASEEFAERQRRTLSGAKILAERLMAD 303 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVAKAGVSV++GGTDVHLVLVDLR+S LDGQ AEDLLHEVGITVNRNAVP DPRPPMVTS Sbjct 304 DVAKAGVSVLTGGTDVHLVLVDLRNSDLDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTS 363 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EFTEVADII TALA G DVSAL+ R ++LA PLY+GLE+ Sbjct 364 GLRIGTPALATRGFGDAEFTEVADIIGTALAAGKGADVSALRARVSKLALDLPLYEGLED 423 Query 421 WSLV 424 W L+ Sbjct 424 WGLM 427 >gi|343925103|ref|ZP_08764635.1| serine hydroxymethyltransferase [Gordonia alkanivorans NBRC 16433] gi|343765034|dbj|GAA11561.1| serine hydroxymethyltransferase [Gordonia alkanivorans NBRC 16433] Length=425 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/422 (82%), Positives = 375/422 (89%), Gaps = 0/422 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 LAE+DPD+A + EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 3 LAELDPDVAAAMNGELSRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 62 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+VDVVE++AR+RAK LFGA+FANVQPHSGAQANAAVL ALM PGE +LGLDLA+GGHL Sbjct 63 CEYVDVVEDIARNRAKELFGADFANVQPHSGAQANAAVLQALMEPGETMLGLDLAHGGHL 122 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGMRLNFSGKLYEN FYGV IDMD VR AL+ +PKVI+AGWSAYPR LDF AF Sbjct 123 THGMRLNFSGKLYENAFYGVSKEDFRIDMDEVRKIALDVKPKVIVAGWSAYPRTLDFEAF 182 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGA L VDMAHFAGLVAAGLHPSPVPHADVVS+TVHKTLGG RSG+I+ KQ++A Sbjct 183 RSIADEVGAHLWVDMAHFAGLVAAGLHPSPVPHADVVSSTVHKTLGGPRSGIILAKQEWA 242 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMH IAGKAVALKIA T EFA+RQRRTLSGA I+A+RL DVAK Sbjct 243 KKLNSAVFPGQQGGPLMHAIAGKAVALKIAGTEEFAERQRRTLSGASILAERLNGEDVAK 302 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGVSV++GGTDVHLVLVDLR+S LDGQ AEDLLH+VGITVNRNAVP DPRPPMVTSGLRI Sbjct 303 AGVSVLTGGTDVHLVLVDLRNSDLDGQQAEDLLHQVGITVNRNAVPFDPRPPMVTSGLRI 362 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRGFGD EFTEVADIIATALA GSS DVSAL+ R ++LA FPLY+GLEEW L+ Sbjct 363 GTPALATRGFGDEEFTEVADIIATALAAGSSADVSALRGRVSKLALDFPLYEGLEEWGLM 422 Query 425 GR 426 R Sbjct 423 SR 424 >gi|262201618|ref|YP_003272826.1| glycine hydroxymethyltransferase [Gordonia bronchialis DSM 43247] gi|262084965|gb|ACY20933.1| Glycine hydroxymethyltransferase [Gordonia bronchialis DSM 43247] Length=435 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/425 (80%), Positives = 374/425 (88%), Gaps = 0/425 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 S LA++DPD+A + EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRY Sbjct 10 SQTLADLDPDVAAAMNGELSRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRY 69 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCE+VDVVE++AR+RAK LFGA+FANVQPHSGAQANAAVL ALM PGE LLGLDLA+G Sbjct 70 YGGCEYVDVVEDIARNRAKELFGADFANVQPHSGAQANAAVLQALMEPGETLLGLDLAHG 129 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGMRLNFSGKLYEN FYGV IDMD VR AL+ RPKVI+AGWSAYPR LDF Sbjct 130 GHLTHGMRLNFSGKLYENAFYGVSKEDFRIDMDEVRKIALDTRPKVIVAGWSAYPRTLDF 189 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFRSIADEVGA L DMAHFAGLVAAGLHPSPVPH+DVVS+TVHKTLGG RSG+I+ KQ Sbjct 190 AAFRSIADEVGAHLWTDMAHFAGLVAAGLHPSPVPHSDVVSSTVHKTLGGPRSGIILAKQ 249 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 +AK +NSAVFPGQQGGPLMHVIA KAVALKIA T EF +RQ+RTLSGA+I+A+RL D Sbjct 250 DWAKKLNSAVFPGQQGGPLMHVIAAKAVALKIAGTEEFKERQQRTLSGAKILAERLTGDD 309 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 V+KAGVSV++GGTDVHLVLVDLR+S LDGQ AEDLLH+VGITVNRNAVP DPRPPMVTSG Sbjct 310 VSKAGVSVLTGGTDVHLVLVDLRNSSLDGQQAEDLLHQVGITVNRNAVPFDPRPPMVTSG 369 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGTPALATRGFGD +FTEVADII TALA G+S DV+AL+ R ++LA FPLYDGLEEW Sbjct 370 LRIGTPALATRGFGDEQFTEVADIIGTALAAGTSADVAALRGRVSKLALDFPLYDGLEEW 429 Query 422 SLVGR 426 L+ R Sbjct 430 GLMSR 434 >gi|312138744|ref|YP_004006080.1| glycine hydroxymethyltransferase [Rhodococcus equi 103S] gi|325676563|ref|ZP_08156241.1| glycine hydroxymethyltransferase [Rhodococcus equi ATCC 33707] gi|311888083|emb|CBH47395.1| glycine hydroxymethyltransferase [Rhodococcus equi 103S] gi|325552741|gb|EGD22425.1| glycine hydroxymethyltransferase [Rhodococcus equi ATCC 33707] Length=436 Score = 669 bits (1727), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/423 (78%), Positives = 370/423 (88%), Gaps = 0/423 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 +A LAE+DP++A +A EL RQRDTLEMIASENFVPRAVL+AQGSVLTNKYAEG PGRRY Sbjct 11 TASLAELDPEVATAMAGELSRQRDTLEMIASENFVPRAVLEAQGSVLTNKYAEGYPGRRY 70 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCE VDVVE+LAR RAK +FGAEFANVQPH+GAQANAAVL ALM+PGE+L+G+DLA+G Sbjct 71 YGGCEFVDVVEDLARGRAKEVFGAEFANVQPHAGAQANAAVLMALMNPGEKLMGMDLAHG 130 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGM+LNFSGKLYE YGV TH++DMD VR TAL +P+V+IAGWSAYPR LDF Sbjct 131 GHLTHGMKLNFSGKLYEVASYGVREDTHVVDMDQVRETALREKPQVLIAGWSAYPRHLDF 190 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFRSIADE+GAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSG+I+ K+ Sbjct 191 AAFRSIADEIGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGMILAKK 250 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 ++AK +NS+VFPGQQGGPLMH IA KAVA+KIA TPEF RQ RTL+G++I+A+RL D Sbjct 251 EWAKKLNSSVFPGQQGGPLMHAIAAKAVAMKIAGTPEFKARQERTLAGSKILAERLGGAD 310 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 VA G+SV++GGTDVHLVLVDLR S LDGQ EDLLHE+GITVNRNAVP DPRPPM SG Sbjct 311 VAGNGISVLTGGTDVHLVLVDLRHSQLDGQQGEDLLHEIGITVNRNAVPFDPRPPMNPSG 370 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGTPALATRGFGD EFTEVADIIATALA G+ DV AL+ R ++LA+ FPLYDGLE W Sbjct 371 LRIGTPALATRGFGDAEFTEVADIIATALAKGADADVPALRARVSKLAQDFPLYDGLENW 430 Query 422 SLV 424 L+ Sbjct 431 GLL 433 >gi|111022822|ref|YP_705794.1| serine hydroxymethyltransferase [Rhodococcus jostii RHA1] gi|110822352|gb|ABG97636.1| glycine hydroxymethyltransferase [Rhodococcus jostii RHA1] Length=431 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/423 (79%), Positives = 371/423 (88%), Gaps = 2/423 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 +APLAE+DP++A+ +A EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRY Sbjct 11 TAPLAELDPEVAQAMAGELARQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRY 70 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCEHVDVVE+LAR+RAK LFGA+FANVQPHSGAQANAAVL ALM+PGE+LLGLDLA+G Sbjct 71 YGGCEHVDVVEDLARNRAKELFGADFANVQPHSGAQANAAVLMALMNPGEKLLGLDLAHG 130 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGM+LNFSGKLY+ YGV H IDMD VR A+ +PKVI+AGWSAYPR DF Sbjct 131 GHLTHGMKLNFSGKLYDVESYGVSKEDHRIDMDEVRKIAVAAQPKVIVAGWSAYPRHEDF 190 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFRSIADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSGLI+ KQ Sbjct 191 AAFRSIADEVGAYLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGLILAKQ 250 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 ++AK +NSAVFPGQQGGPLMH IA KAV+LKIA T EF DRQ+RTL+GA+I+A+RL D Sbjct 251 EWAKKLNSAVFPGQQGGPLMHAIAAKAVSLKIAGTEEFKDRQQRTLTGAKILAERLTGAD 310 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 VA GVSV++GGTDVHLVLVDLR+S LDGQ EDLLHEVGITVNRNAVP DPRPPMVTSG Sbjct 311 VADKGVSVLTGGTDVHLVLVDLRNSQLDGQQGEDLLHEVGITVNRNAVPFDPRPPMVTSG 370 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGT ALA+RGFGD +FTEVADII TALA GSS DV LK R ++LA FPLY+GLE+W Sbjct 371 LRIGTAALASRGFGDEQFTEVADIIGTALA-GSS-DVETLKSRVSKLAADFPLYEGLEDW 428 Query 422 SLV 424 L+ Sbjct 429 RLI 431 >gi|226365330|ref|YP_002783113.1| serine hydroxymethyltransferase [Rhodococcus opacus B4] gi|226243820|dbj|BAH54168.1| serine hydroxymethyltransferase [Rhodococcus opacus B4] Length=431 Score = 665 bits (1716), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/423 (78%), Positives = 367/423 (87%), Gaps = 2/423 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 +APLAE+DP++A+ +A EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRY Sbjct 11 TAPLAELDPEVAQAMAGELARQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRY 70 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCEHVDVVE+LAR RAK LFGA+FANVQPHSGAQANAAVL ALM+PGE+LLGLDLA+G Sbjct 71 YGGCEHVDVVEDLARTRAKELFGADFANVQPHSGAQANAAVLMALMNPGEKLLGLDLAHG 130 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGM+LNFSGKLY+ YGV H IDMD VR A+ +PKVI+AGWSAYPR DF Sbjct 131 GHLTHGMKLNFSGKLYDVESYGVSKEDHRIDMDEVRKIAVAAQPKVIVAGWSAYPRHEDF 190 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFRSIADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSGLI+ KQ Sbjct 191 AAFRSIADEVGAYLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGLILAKQ 250 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 ++AK +NSAVFPGQQGGPLMH IA KAV+LKIA T EF DRQ+RTL+GA+I+A+RL D Sbjct 251 EWAKKLNSAVFPGQQGGPLMHAIAAKAVSLKIAGTDEFKDRQQRTLTGAKILAERLTGSD 310 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 V GVSV++GGTDVHLVLVDLR+S LDGQ EDLLHEVGITVNRNAVP DPRPPMVTSG Sbjct 311 VVDKGVSVLTGGTDVHLVLVDLRNSQLDGQQGEDLLHEVGITVNRNAVPFDPRPPMVTSG 370 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGT ALA+RGFGD +FTEVADII TALA S DV LK R ++LA FPLY+GLE+W Sbjct 371 LRIGTAALASRGFGDEQFTEVADIIGTALAGAS--DVETLKSRVSKLAADFPLYEGLEDW 428 Query 422 SLV 424 L+ Sbjct 429 RLI 431 >gi|161485985|ref|NP_737668.2| serine hydroxymethyltransferase [Corynebacterium efficiens YS-314] gi|259506984|ref|ZP_05749884.1| glycine hydroxymethyltransferase [Corynebacterium efficiens YS-314] gi|29336728|sp|Q8FQR1.2|GLYA_COREF RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase gi|259165436|gb|EEW49990.1| glycine hydroxymethyltransferase [Corynebacterium efficiens YS-314] Length=434 Score = 664 bits (1714), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/421 (76%), Positives = 364/421 (87%), Gaps = 0/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PL+E+DP++A+ +A EL RQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEG PGRRYYG Sbjct 14 PLSEIDPEVAQAIAGELSRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRRYYG 73 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE VD++E+LARDRAKALF AEFANVQPHSGAQANAAVL L PG++++GL LA+GGH Sbjct 74 GCEQVDIIEDLARDRAKALFDAEFANVQPHSGAQANAAVLMTLADPGDKIMGLSLAHGGH 133 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGM+LNFSGKLYE YGVDP T L+DMD VR A++ +PKVIIAGWSAYPR LDFAA Sbjct 134 LTHGMKLNFSGKLYEVAAYGVDPDTMLVDMDQVREQAIKEQPKVIIAGWSAYPRHLDFAA 193 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 FR IADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSG+I+ KQ Y Sbjct 194 FREIADEVGATLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGIILAKQDY 253 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AK +NS+VFPGQQGGPLMH IA KA ALKIA T +FA+RQ RT+ GARI+A+RL A D Sbjct 254 AKKLNSSVFPGQQGGPLMHAIAAKATALKIAGTDQFAERQARTIEGARILAERLTASDAK 313 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AG+ V++GGTDVHLVL DLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 314 AAGIDVLTGGTDVHLVLADLRNSEMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 373 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALATRGF T FTEVADII TALA G S D+ +L+ R T+LA +PLY+GLE+W++ Sbjct 374 IGTPALATRGFDATAFTEVADIIGTALAQGKSADLESLQARVTKLAEQYPLYEGLEDWTI 433 Query 424 V 424 V Sbjct 434 V 434 >gi|296140813|ref|YP_003648056.1| glycine hydroxymethyltransferase [Tsukamurella paurometabola DSM 20162] gi|296028947|gb|ADG79717.1| Glycine hydroxymethyltransferase [Tsukamurella paurometabola DSM 20162] Length=432 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/425 (79%), Positives = 372/425 (88%), Gaps = 0/425 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 +A LAE+DP++A + EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRY Sbjct 8 TASLAELDPEVAAAMNGELARQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRY 67 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCE+VDVVE+LAR+RAK LFGAEFANVQPH+GAQANAAVL ALM PGE L+GLDLA+G Sbjct 68 YGGCEYVDVVEDLARNRAKELFGAEFANVQPHAGAQANAAVLQALMEPGETLMGLDLAHG 127 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGMRLNFSGKLYEN FYGV H +DMD VR AL+ +PKVI+AGWSAYPR LDF Sbjct 128 GHLTHGMRLNFSGKLYENVFYGVSKEDHRVDMDEVRKIALDSKPKVIVAGWSAYPRHLDF 187 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFRSIADEVGA L VDMAHFAGLVAAGLHPSPVPHADVVS+TVHKTLGG RSG+I+ KQ Sbjct 188 AAFRSIADEVGAHLWVDMAHFAGLVAAGLHPSPVPHADVVSSTVHKTLGGPRSGIILAKQ 247 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 ++AK +NSAVFPGQQGGPLMHVIA KAVALK+A T EF ++Q+RTL GA+I+A+RL A D Sbjct 248 EWAKKLNSAVFPGQQGGPLMHVIAAKAVALKVAGTEEFREKQQRTLEGAKILAERLTAQD 307 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 VA AGV+V++GGTDVHLVLVDLR+S LDGQ AEDLLHEVGITVNRNAVP DPRPPMVTSG Sbjct 308 VADAGVTVLTGGTDVHLVLVDLRNSDLDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSG 367 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGT ALA+RGFG EFTEVADII TALA G + D+SAL+ R + LA PLYDGLE+W Sbjct 368 LRIGTAALASRGFGAAEFTEVADIIGTALALGKAADLSALRARVSALALEVPLYDGLEDW 427 Query 422 SLVGR 426 L+ R Sbjct 428 GLLSR 432 >gi|213965536|ref|ZP_03393731.1| serine hydroxymethyltransferase [Corynebacterium amycolatum SK46] gi|213951920|gb|EEB63307.1| serine hydroxymethyltransferase [Corynebacterium amycolatum SK46] Length=433 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/420 (76%), Positives = 365/420 (87%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L E+DPD+AE +A EL RQRD LEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 14 LRELDPDLAEAMAGELSRQRDMLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 73 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+VDVVE++AR+RAK LFGAEFANVQPH+GAQANAAVLHAL++ G++++GLDLA+GGHL Sbjct 74 CEYVDVVEDMARNRAKELFGAEFANVQPHAGAQANAAVLHALINAGDKIMGLDLAHGGHL 133 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM+LNFSGKLY YGVD T IDMD VR AL +P V+IAGWSAYPR LDF AF Sbjct 134 THGMKLNFSGKLYHVAAYGVDKDTMRIDMDKVREQALAEKPDVLIAGWSAYPRHLDFEAF 193 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGAKL DMAHFAGLVAAGLHPSPVPH+DVVSTTVHKTLGG RSG+I+ KQ+YA Sbjct 194 RSIADEVGAKLWTDMAHFAGLVAAGLHPSPVPHSDVVSTTVHKTLGGPRSGMILAKQEYA 253 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMH IAGKAVALKIA T EF +RQ RTL+GARI+A+RL A D A+ Sbjct 254 KKLNSAVFPGQQGGPLMHAIAGKAVALKIAGTEEFKERQERTLAGARILAERLTASDCAE 313 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV V++GGTDVHLVL DLR+S ++GQ AEDLLH VGITVNRNAVP DPRPPMVTSGLRI Sbjct 314 AGVDVLTGGTDVHLVLADLRNSEMNGQEAEDLLHAVGITVNRNAVPFDPRPPMVTSGLRI 373 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRG + FTEVAD+I TALA G + DV +L+ R +++A+ FPLYDG+E+W+L+ Sbjct 374 GTPALATRGLDEKAFTEVADVIGTALAAGKNADVDSLRARVSKIAQEFPLYDGIEDWNLI 433 >gi|23492896|dbj|BAC17868.1| serine hydroxymethyltransferase [Corynebacterium efficiens YS-314] Length=515 Score = 661 bits (1705), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/421 (76%), Positives = 364/421 (87%), Gaps = 0/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PL+E+DP++A+ +A EL RQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEG PGRRYYG Sbjct 95 PLSEIDPEVAQAIAGELSRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRRYYG 154 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE VD++E+LARDRAKALF AEFANVQPHSGAQANAAVL L PG++++GL LA+GGH Sbjct 155 GCEQVDIIEDLARDRAKALFDAEFANVQPHSGAQANAAVLMTLADPGDKIMGLSLAHGGH 214 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGM+LNFSGKLYE YGVDP T L+DMD VR A++ +PKVIIAGWSAYPR LDFAA Sbjct 215 LTHGMKLNFSGKLYEVAAYGVDPDTMLVDMDQVREQAIKEQPKVIIAGWSAYPRHLDFAA 274 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 FR IADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSG+I+ KQ Y Sbjct 275 FREIADEVGATLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGIILAKQDY 334 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AK +NS+VFPGQQGGPLMH IA KA ALKIA T +FA+RQ RT+ GARI+A+RL A D Sbjct 335 AKKLNSSVFPGQQGGPLMHAIAAKATALKIAGTDQFAERQARTIEGARILAERLTASDAK 394 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AG+ V++GGTDVHLVL DLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 395 AAGIDVLTGGTDVHLVLADLRNSEMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 454 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALATRGF T FTEVADII TALA G S D+ +L+ R T+LA +PLY+GLE+W++ Sbjct 455 IGTPALATRGFDATAFTEVADIIGTALAQGKSADLESLQARVTKLAEQYPLYEGLEDWTI 514 Query 424 V 424 V Sbjct 515 V 515 >gi|226307739|ref|YP_002767699.1| serine hydroxymethyltransferase [Rhodococcus erythropolis PR4] gi|229493868|ref|ZP_04387640.1| serine hydroxymethyltransferase [Rhodococcus erythropolis SK121] gi|226186856|dbj|BAH34960.1| serine hydroxymethyltransferase [Rhodococcus erythropolis PR4] gi|229319145|gb|EEN84994.1| serine hydroxymethyltransferase [Rhodococcus erythropolis SK121] Length=435 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/425 (77%), Positives = 364/425 (86%), Gaps = 2/425 (0%) Query 2 SAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRY 61 SA LAE+DP++AE +A EL RQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEG PGRRY Sbjct 11 SASLAELDPEVAEAMAGELARQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRRY 70 Query 62 YGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANG 121 YGGCEHVDV+E+LAR+RAK LFGAEFANVQPHSGAQANAAVL ALM+PGE+LLGLDLA+G Sbjct 71 YGGCEHVDVIEDLARNRAKELFGAEFANVQPHSGAQANAAVLMALMNPGEKLLGLDLAHG 130 Query 122 GHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDF 181 GHLTHGM+LNFSGKLY+ YGV H IDMD VR+ AL +PKVI+AGWSAYPR DF Sbjct 131 GHLTHGMKLNFSGKLYDVASYGVSKEDHRIDMDEVRSIALAEKPKVIVAGWSAYPRQQDF 190 Query 182 AAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQ 241 AAFR+IADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSGLI+ K+ Sbjct 191 AAFRAIADEVGAYLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGLILAKK 250 Query 242 QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPD 301 ++AK +NSAVFPGQQGGPLMH IA KAV KIAA EF DRQ RTLSGARI+A+RL D Sbjct 251 EWAKKLNSAVFPGQQGGPLMHAIAAKAVTFKIAAGEEFKDRQARTLSGARILAERLGNKD 310 Query 302 VAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSG 361 VA G+SV++GGTDVHLVLVDLR+S LDGQ EDLLHE+GITVNRNAVP DPRPPM TSG Sbjct 311 VADQGISVLTGGTDVHLVLVDLRNSQLDGQQGEDLLHEIGITVNRNAVPFDPRPPMTTSG 370 Query 362 LRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 LRIGT ALATRGFGD EFTEVADII TALA + D+ AL+ R +LA PLYDGLE W Sbjct 371 LRIGTAALATRGFGDAEFTEVADIIGTALA--GNADLPALRARVAKLALDLPLYDGLENW 428 Query 422 SLVGR 426 L+ + Sbjct 429 GLLSK 433 >gi|54026787|ref|YP_121029.1| serine hydroxymethyltransferase [Nocardia farcinica IFM 10152] gi|61213311|sp|Q5YQ76.1|GLYA_NOCFA RecName: Full=Serine hydroxymethyltransferase; Short=SHMT; Short=Serine methylase gi|54018295|dbj|BAD59665.1| putative serine hydroxymethyltransferase [Nocardia farcinica IFM 10152] Length=431 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/421 (79%), Positives = 361/421 (86%), Gaps = 2/421 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L E+DP++A +A EL R+RDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 13 LGELDPELAAAMAGELARERDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 72 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+VDVVENLAR+RAK LFGAEFANVQPHSGAQANAAVL +LM PG+RLLGLDLA+GGHL Sbjct 73 CENVDVVENLARERAKELFGAEFANVQPHSGAQANAAVLMSLMDPGDRLLGLDLAHGGHL 132 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGMRLNFSGKLYE YGV H +DMD VR AL +PKVI+AGWSAYPR DFAAF Sbjct 133 THGMRLNFSGKLYEVHSYGVSKEDHRVDMDEVRTIALGAKPKVIVAGWSAYPRHQDFAAF 192 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 R+IADEVGA L VDMAHFAGLVAAGLHPSPVP+ADVVS+TVHKTLGG RSGLI+ KQ++A Sbjct 193 RAIADEVGAYLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGLILAKQEFA 252 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K INSAVFPGQQGGPLMH IA KAVA KIA T EF DRQ+RTLSGA+I+A+RL DVA Sbjct 253 KKINSAVFPGQQGGPLMHAIAAKAVAFKIAGTEEFRDRQQRTLSGAKILAERLTGADVAD 312 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 G+SV++GGTDVHLVLVDLR+S LDGQ EDLLHE+GITVNRNAVP DPRPPMVTSGLRI Sbjct 313 KGISVLTGGTDVHLVLVDLRNSQLDGQQGEDLLHEIGITVNRNAVPFDPRPPMVTSGLRI 372 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GT ALATRGFGD EFTEVADIIATALA GS D L+ R LA+ PLY GLE+W L+ Sbjct 373 GTAALATRGFGDAEFTEVADIIATALAGGS--DAETLRGRVRALAQRVPLYQGLEDWHLL 430 Query 425 G 425 G Sbjct 431 G 431 >gi|300781596|ref|ZP_07091450.1| glycine hydroxymethyltransferase [Corynebacterium genitalium ATCC 33030] gi|300533303|gb|EFK54364.1| glycine hydroxymethyltransferase [Corynebacterium genitalium ATCC 33030] Length=430 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/420 (75%), Positives = 359/420 (86%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 LA++DPD+ E + E+ RQR+TLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 11 LAQLDPDVYEQILGEVSRQRNTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 70 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+VDV+E++ARDRAK LFGAE+ANVQPHSGAQANAAVLHAL+ PG+ ++GL LA+GGHL Sbjct 71 CENVDVIEDIARDRAKELFGAEYANVQPHSGAQANAAVLHALIKPGDTIMGLSLAHGGHL 130 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM++NFSG+LY Y VDP T LIDMD VR ALE +P+VIIAGWSAYPR +DF AF Sbjct 131 THGMKINFSGRLYNVVAYEVDPDTMLIDMDKVRELALEHKPQVIIAGWSAYPRTVDFEAF 190 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 R+IADEVGA L DMAHFAGLVAAGLHPSPVPH+DVVSTT+HKTLGG RSG+I+ KQ YA Sbjct 191 RAIADEVGAYLWTDMAHFAGLVAAGLHPSPVPHSDVVSTTIHKTLGGPRSGMILAKQDYA 250 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMHV+A KA ALKIA TPEF DRQ RTL GARI+A+RL A D + Sbjct 251 KQLNSAVFPGQQGGPLMHVVAAKATALKIAGTPEFKDRQERTLEGARILAERLTASDCKE 310 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 GV V++GGTDVHLVL DLR+S LDGQ AEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI Sbjct 311 VGVDVLTGGTDVHLVLADLRNSELDGQQAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 370 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GT ALATRGF FTE ADII TALA G++ DV +L+ R T+LA +PLY GLE+W ++ Sbjct 371 GTSALATRGFDQQAFTETADIIGTALAQGTNADVESLRARVTKLAENYPLYPGLEDWKML 430 >gi|225022970|ref|ZP_03712162.1| hypothetical protein CORMATOL_03016 [Corynebacterium matruchotii ATCC 33806] gi|224944193|gb|EEG25402.1| hypothetical protein CORMATOL_03016 [Corynebacterium matruchotii ATCC 33806] Length=434 Score = 653 bits (1685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/421 (78%), Positives = 360/421 (86%), Gaps = 2/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PLAE DPD+A +A ELGRQR TLEMIASENFVPR+VLQAQGSV TNKYAEG PGRRYYG Sbjct 16 PLAEFDPDVAAAIAGELGRQRATLEMIASENFVPRSVLQAQGSVFTNKYAEGYPGRRYYG 75 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE+ D+VENLARDRAKALFGAEFANVQPH+GAQANAAVL AL +PG++++GL LA+GGH Sbjct 76 GCENSDIVENLARDRAKALFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLALAHGGH 135 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGMRLNFSGKLY+ Y VDP T IDMD VR AL RP+VIIAGWSAYPR DFAA Sbjct 136 LTHGMRLNFSGKLYQVVAYEVDPTTFRIDMDRVREQALAERPQVIIAGWSAYPRHQDFAA 195 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 FR+IADEVGAKL VDMAHFAGLVAAGLHPSP+PHADVVSTTVHKTLGG RSG+I+ KQ+Y Sbjct 196 FRAIADEVGAKLWVDMAHFAGLVAAGLHPSPIPHADVVSTTVHKTLGGPRSGMILAKQEY 255 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AKAINSAVFPGQQGGPLMH IA KAVA+KIAAT +F RQ+RTL GARI+A+RL A D Sbjct 256 AKAINSAVFPGQQGGPLMHAIAAKAVAMKIAATDQFRQRQQRTLDGARILAERLTAADCQ 315 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AG+ V++GGTDVHL LVDLR+S LDG+ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 316 AAGIGVLTGGTDVHLALVDLRNSQLDGKQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 375 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALATRGF FTEVADIIA AL ++ V L+ R +LA AFPLYDGLE+W L Sbjct 376 IGTPALATRGFDAAAFTEVADIIAEALTNATA--VPDLQARVAKLADAFPLYDGLEDWCL 433 Query 424 V 424 + Sbjct 434 L 434 >gi|19552219|ref|NP_600221.1| serine hydroxymethyltransferase [Corynebacterium glutamicum ATCC 13032] gi|62389884|ref|YP_225286.1| serine hydroxymethyltransferase [Corynebacterium glutamicum ATCC 13032] gi|145295144|ref|YP_001137965.1| serine hydroxymethyltransferase [Corynebacterium glutamicum R] 7 more sequence titles Length=434 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/421 (76%), Positives = 360/421 (86%), Gaps = 0/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PL E+DP++A +A EL RQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEG PGRRYYG Sbjct 14 PLNELDPEVAAAIAGELARQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRRYYG 73 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE VD++E+LARDRAKALFGAEFANVQPHSGAQANAAVL L PG++++GL LA+GGH Sbjct 74 GCEQVDIIEDLARDRAKALFGAEFANVQPHSGAQANAAVLMTLAEPGDKIMGLSLAHGGH 133 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGM+LNFSGKLYE YGVDP T +DMD VR AL+ +PKVIIAGWSAYPR LDF A Sbjct 134 LTHGMKLNFSGKLYEVVAYGVDPETMRVDMDQVREIALKEQPKVIIAGWSAYPRHLDFEA 193 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 F+SIA EVGAKL VDMAHFAGLVAAGLHPSPVP++DVVS+TVHKTLGG RSG+I+ KQ+Y Sbjct 194 FQSIAAEVGAKLWVDMAHFAGLVAAGLHPSPVPYSDVVSSTVHKTLGGPRSGIILAKQEY 253 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AK +NS+VFPGQQGGPLMH +A KA +LKIA T +F DRQ RTL GARI+A+RL A D Sbjct 254 AKKLNSSVFPGQQGGPLMHAVAAKATSLKIAGTEQFRDRQARTLEGARILAERLTASDAK 313 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AGV V++GGTDVHLVL DLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 314 AAGVDVLTGGTDVHLVLADLRNSQMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 373 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALATRGF FTEVADII TALA G S D+ +L+ R +LA +PLY+GLE+W++ Sbjct 374 IGTPALATRGFDIPAFTEVADIIGTALANGKSADIESLRGRVAKLAADYPLYEGLEDWTI 433 Query 424 V 424 V Sbjct 434 V 434 >gi|306835721|ref|ZP_07468727.1| glycine hydroxymethyltransferase [Corynebacterium accolens ATCC 49726] gi|304568439|gb|EFM43998.1| glycine hydroxymethyltransferase [Corynebacterium accolens ATCC 49726] Length=427 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/420 (75%), Positives = 358/420 (86%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L ++DPD+ + E+ RQR+TLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 8 LRDLDPDVFGAIQGEISRQRETLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 67 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CEHVDVVE+LARDRAKALF AEFANVQPHSGAQANAAVL ++ PG+++LGL LA+GGHL Sbjct 68 CEHVDVVEDLARDRAKALFNAEFANVQPHSGAQANAAVLSSIAEPGDKILGLSLAHGGHL 127 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM+LNFSGKLY+ YGVDP T +DMD +R AL+ +PKVII GWSAYPR LDFAAF Sbjct 128 THGMKLNFSGKLYDVAAYGVDPETMRVDMDKLREQALKEKPKVIIGGWSAYPRTLDFAAF 187 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 R IADEVGA L VDMAHFAGLVAAGLHP+PV HAD+VSTTVHKTLGG RSG+I+ KQ+YA Sbjct 188 REIADEVGAYLWVDMAHFAGLVAAGLHPNPVEHADIVSTTVHKTLGGPRSGMILAKQEYA 247 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NS VFPGQQGGPLMH +A KA+++KIAA+ EF +RQ RTL GARI+ADRL+A D Sbjct 248 KKLNSNVFPGQQGGPLMHAVAAKAISMKIAASEEFKERQERTLEGARILADRLLAEDTQA 307 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV VVSGGTDVHLVLVDLR+S LDGQ AEDLLH+VGITVNRNAVPNDPRPPMVTSGLRI Sbjct 308 AGVDVVSGGTDVHLVLVDLRNSQLDGQQAEDLLHQVGITVNRNAVPNDPRPPMVTSGLRI 367 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GT ALATRG FTEVAD+I TALA G++ DV AL+ R ++A +PLY+GLE+W LV Sbjct 368 GTSALATRGLDAEAFTEVADVIGTALAQGNNADVEALRRRVDKIAEDYPLYEGLEDWKLV 427 >gi|319950195|ref|ZP_08024122.1| serine hydroxymethyltransferase [Dietzia cinnamea P4] gi|319436099|gb|EFV91292.1| serine hydroxymethyltransferase [Dietzia cinnamea P4] Length=434 Score = 652 bits (1682), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/426 (75%), Positives = 364/426 (86%), Gaps = 1/426 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 SA L+E+DP++AE +A EL RQRDTLEMIASENFVPR+VLQAQGSVLTNKYAEG PGRR Sbjct 9 FSASLSELDPEVAEAMAGELARQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRR 68 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCEHVDV+ENLARDRAK +FGA++ANVQPH+GAQANAAVL AL +PG +++GL LA+ Sbjct 69 YYGGCEHVDVIENLARDRAKEVFGAKYANVQPHAGAQANAAVLMALAAPGSKIMGLSLAH 128 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM+LNFSG+LYE Y VD T L+DMDAVR AL +P VIIAGWSAYPR LD Sbjct 129 GGHLTHGMKLNFSGQLYEVAAYEVDAETMLVDMDAVREMALAEKPDVIIAGWSAYPRTLD 188 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FA FR IADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSG+I+ Sbjct 189 FAKFREIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGMILTN 248 Query 241 Q-QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMA 299 + K +NS+VFPGQQGGPLMH IA KA A+KIA T +F +RQ+RTL GA+I+A+RL A Sbjct 249 DLELFKKLNSSVFPGQQGGPLMHAIAAKATAMKIAGTEQFRERQQRTLEGAKILAERLTA 308 Query 300 PDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVT 359 D AGVSV++GGTDVHLVLVDLRDS LDGQ AEDLLHEVGITVNRNAVP DPRPPMVT Sbjct 309 EDCRNAGVSVLTGGTDVHLVLVDLRDSELDGQQAEDLLHEVGITVNRNAVPFDPRPPMVT 368 Query 360 SGLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLE 419 SGLRIGTPALATRGF +F EVADII ALA G + DV+AL++R T LAR+ PLY+GLE Sbjct 369 SGLRIGTPALATRGFTADDFREVADIIGAALAAGKNADVAALRERVTALARSKPLYEGLE 428 Query 420 EWSLVG 425 +W+++G Sbjct 429 DWTILG 434 >gi|305682105|ref|ZP_07404909.1| glycine hydroxymethyltransferase [Corynebacterium matruchotii ATCC 14266] gi|305658578|gb|EFM48081.1| glycine hydroxymethyltransferase [Corynebacterium matruchotii ATCC 14266] Length=427 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/421 (77%), Positives = 359/421 (86%), Gaps = 2/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PLAE DPD+A +A ELGRQR TLEMIASENFVPR+VLQAQGSV TNKYAEG PGRRYYG Sbjct 9 PLAEFDPDVAAAIAGELGRQRATLEMIASENFVPRSVLQAQGSVFTNKYAEGYPGRRYYG 68 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE+ D+VENLARDRAKALFGAEFANVQPH+GAQANAAVL AL +PG++++GL LA+GGH Sbjct 69 GCENSDIVENLARDRAKALFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLSLAHGGH 128 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGMRLNFSGKLY+ Y VDP T IDMD VR AL RP+VIIAGWSAYPR DFAA Sbjct 129 LTHGMRLNFSGKLYQVVAYEVDPTTFRIDMDRVREQALAERPQVIIAGWSAYPRHQDFAA 188 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 FR+IADEVGAKL VDMAHFAGLVAAGLHPSP+PHADVVSTTVHKTLGG RSG+I+ KQ+Y Sbjct 189 FRAIADEVGAKLWVDMAHFAGLVAAGLHPSPIPHADVVSTTVHKTLGGPRSGMILAKQEY 248 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AKAINSAVFPGQQGGPLMH IA KAVA+KIAAT +F RQ+RTL GA I+A+RL A D Sbjct 249 AKAINSAVFPGQQGGPLMHAIAAKAVAMKIAATDQFRQRQQRTLDGAHILAERLTAADCQ 308 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AG+ V++GGTDVHL LVDLR+S LDG+ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 309 AAGIGVLTGGTDVHLALVDLRNSQLDGKQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 368 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALATRGF FTEVADIIA AL ++ V L+ R +LA AFPLYDGLE+W L Sbjct 369 IGTPALATRGFDAAAFTEVADIIAEALTNATA--VPDLQARVAKLADAFPLYDGLEDWRL 426 Query 424 V 424 + Sbjct 427 I 427 >gi|227501563|ref|ZP_03931612.1| serine hydroxymethyltransferase [Corynebacterium accolens ATCC 49725] gi|227077588|gb|EEI15551.1| serine hydroxymethyltransferase [Corynebacterium accolens ATCC 49725] Length=427 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/420 (75%), Positives = 357/420 (85%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L ++DPD+ + E+ RQR+TLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 8 LRDLDPDVFGAIQGEISRQRETLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 67 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CEHVDVVE+LARDRAKALF AEFANVQPHSGAQANAAVL ++ PG+++LGL LA+GGHL Sbjct 68 CEHVDVVEDLARDRAKALFNAEFANVQPHSGAQANAAVLASIAEPGDKILGLSLAHGGHL 127 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM+LNFSGKLY+ YGVDP T +DMD +R A+E +PKVII GWSAYPR LDFAAF Sbjct 128 THGMKLNFSGKLYDVAAYGVDPETMRVDMDKLREQAIEEKPKVIIGGWSAYPRTLDFAAF 187 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 R IADEVGA L VDMAHFAGLVAAGLHP+PV HAD+VSTTVHKTLGG RSG+I+ KQ+YA Sbjct 188 REIADEVGAYLWVDMAHFAGLVAAGLHPNPVEHADIVSTTVHKTLGGPRSGMILAKQEYA 247 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NS VFPGQQGGPLMH +A KA+++KIAA+ EF +RQ RTL GARI+ADRL+A D Sbjct 248 KKLNSNVFPGQQGGPLMHAVAAKAISMKIAASEEFKERQERTLEGARILADRLLAEDTRA 307 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV VVSGGTDVHLVL DLR+S LDGQ AEDLLH+VGITVNRNAVPNDPRPPMVTSGLRI Sbjct 308 AGVDVVSGGTDVHLVLADLRNSQLDGQQAEDLLHQVGITVNRNAVPNDPRPPMVTSGLRI 367 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GT ALATRG FTEVAD+I TALA G++ DV AL+ R ++A +PLY+GLE+W LV Sbjct 368 GTSALATRGLDAEAFTEVADVIGTALAQGNNADVEALRRRVDKIAEDYPLYEGLEDWKLV 427 >gi|332669649|ref|YP_004452657.1| glycine hydroxymethyltransferase [Cellulomonas fimi ATCC 484] gi|332338687|gb|AEE45270.1| Glycine hydroxymethyltransferase [Cellulomonas fimi ATCC 484] Length=429 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/417 (77%), Positives = 359/417 (87%), Gaps = 0/417 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 ++E+DP+IA +L EL RQ+ TLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 13 ISELDPEIAAVLDGELARQQGTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 72 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE VD+ EN+A DRAKALFGAE ANVQPHSGA ANAAVLHAL++ G+++LGL+LA+GGHL Sbjct 73 CEQVDIAENIAIDRAKALFGAEHANVQPHSGATANAAVLHALINAGDKILGLELAHGGHL 132 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM++NFSGKLY+ YGVDP T I+ +A+RA AL RP VII GWSAYPR LDFAA Sbjct 133 THGMKINFSGKLYDVAAYGVDPQTFRIEPEAIRAAALAHRPDVIIGGWSAYPRHLDFAAM 192 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 R IADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVS+TVHKT+GG RSG I+ +++YA Sbjct 193 REIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSSTVHKTIGGPRSGFILSREEYA 252 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K I+SAVFPGQQGGPLMHVIA KAV+ K+A T EF DRQ+RT+ GARIIADRL A DVA Sbjct 253 KKIDSAVFPGQQGGPLMHVIAAKAVSFKVAGTEEFKDRQQRTIDGARIIADRLTAADVAN 312 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGVSV++GGTDVHLVLVDLR S LDGQ AEDLLH GITVNRNAVP DPRPP VTSGLRI Sbjct 313 AGVSVLTGGTDVHLVLVDLRHSDLDGQQAEDLLHAAGITVNRNAVPFDPRPPRVTSGLRI 372 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEW 421 GTPALATRGFGD EFTEVADIIATAL G++ DV AL+ R +LA AFPLY GL+++ Sbjct 373 GTPALATRGFGDAEFTEVADIIATALVGGAATDVEALRARVAKLAEAFPLYSGLQQY 429 >gi|269796075|ref|YP_003315530.1| serine hydroxymethyltransferase [Sanguibacter keddieii DSM 10542] gi|269098260|gb|ACZ22696.1| serine hydroxymethyltransferase [Sanguibacter keddieii DSM 10542] Length=430 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/421 (76%), Positives = 359/421 (86%), Gaps = 0/421 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 M+ +A+VDP+IA +L EL RQRDTLEMIASENFVPRAVL+AQGSVLTNKYAEG PG+R Sbjct 10 MNQGIAQVDPEIAAVLDGELARQRDTLEMIASENFVPRAVLEAQGSVLTNKYAEGYPGKR 69 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE VD+ E LA R KAL+GAE ANVQPHSGA ANAAVLHAL+S G+++LGL+LA+ Sbjct 70 YYGGCEQVDIAETLAIQRVKALYGAEHANVQPHSGATANAAVLHALISKGDKILGLELAH 129 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM++NFSG+LYE YGVDP THL+DMD VR TAL RP VII GWSAYPR LD Sbjct 130 GGHLTHGMKINFSGRLYEVAAYGVDPETHLVDMDKVRETALAERPDVIIGGWSAYPRHLD 189 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 FAAFRSIADEVGAKL VDMAHFAGLVAA LHP+PV HADVVS+TVHKT+GG RSG I+ + Sbjct 190 FAAFRSIADEVGAKLWVDMAHFAGLVAADLHPNPVQHADVVSSTVHKTIGGPRSGFILSR 249 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 ++YAK I+SAVFPGQQGGPLMHV+A KAVA KIAA+ EFA+RQ R L GA+IIADRL A Sbjct 250 EEYAKKIDSAVFPGQQGGPLMHVVAAKAVAFKIAASEEFAERQHRVLRGAKIIADRLTAA 309 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DV +AGVSV++GGTDVHLVLVDLR S LDGQ AEDLLH VGITVNRNAVP DPRPP VTS Sbjct 310 DVTEAGVSVLTGGTDVHLVLVDLRHSELDGQQAEDLLHAVGITVNRNAVPFDPRPPRVTS 369 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALA RGFGD EFTEVADIIATAL G++ DV +LK R +L FPLY GL++ Sbjct 370 GLRIGTPALAARGFGDEEFTEVADIIATALKGGAATDVESLKARVDKLTGDFPLYPGLQQ 429 Query 421 W 421 + Sbjct 430 Y 430 >gi|300858146|ref|YP_003783129.1| serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis FRC41] gi|300685600|gb|ADK28522.1| serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis FRC41] gi|302205867|gb|ADL10209.1| Serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis C231] gi|302330425|gb|ADL20619.1| Serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis 1002] gi|308276102|gb|ADO26001.1| Serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis I19] gi|341824539|gb|AEK92060.1| Serine hydroxymethyltransferase [Corynebacterium pseudotuberculosis PAT10] Length=429 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/420 (75%), Positives = 359/420 (86%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L+E+DP++A +A EL RQR TLEMIASENFVPRAVLQAQGSV TNKYAEG PGRRYYGG Sbjct 10 LSELDPEVAGAIAGELDRQRSTLEMIASENFVPRAVLQAQGSVFTNKYAEGYPGRRYYGG 69 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+ D+VE+LAR+RAK +FGAEFANVQPH+GAQANAAVL AL +PG++++GL LA+GGHL Sbjct 70 CENADIVEDLARNRAKEVFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLSLAHGGHL 129 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM LNFSGKLY+ Y VDP T +DMD VR AL +P+V+IAGWSAYPR DF AF Sbjct 130 THGMHLNFSGKLYQVAAYEVDPETFRVDMDKVREQALAEKPQVLIAGWSAYPRQQDFEAF 189 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSG+I+ KQ+YA Sbjct 190 RSIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGMILAKQEYA 249 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMH IA KAVA+KIAAT EF +RQ RTL GA++IA+RL++ D Sbjct 250 KKLNSAVFPGQQGGPLMHAIAAKAVAMKIAATEEFKNRQERTLEGAKLIAERLVSADCKA 309 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV V++GGTDVHLVLVDLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLRI Sbjct 310 AGVDVLTGGTDVHLVLVDLRNSQMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLRI 369 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRGF F+EVADII TALA G++ +V L R T+LA +PLY+GLE+W L+ Sbjct 370 GTPALATRGFDTAGFSEVADIIGTALAQGTNANVPELWARVTKLAEQYPLYEGLEDWKLL 429 >gi|340794900|ref|YP_004760363.1| serine hydroxymethyltransferase [Corynebacterium variabile DSM 44702] gi|340534810|gb|AEK37290.1| serine hydroxymethyltransferase [Corynebacterium variabile DSM 44702] Length=430 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/421 (75%), Positives = 357/421 (85%), Gaps = 0/421 (0%) Query 4 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 63 PL E+DP++A +A EL RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYG Sbjct 10 PLGELDPEVASAIAGELSRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYG 69 Query 64 GCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGH 123 GCE+VD++E+LARDRAKA+FGAEFANVQPHSGAQANAAVL +L +PG++++GL LA+GGH Sbjct 70 GCENVDIIEDLARDRAKAVFGAEFANVQPHSGAQANAAVLMSLANPGDKIMGLSLAHGGH 129 Query 124 LTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAA 183 LTHGM+LNFSGKLYE Y VDP T +DMD VR A+ +P+VII GWSAYPR DF A Sbjct 130 LTHGMKLNFSGKLYEVAAYEVDPETMRLDMDKVREQAIAEKPQVIIGGWSAYPRHQDFEA 189 Query 184 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQY 243 FRSIADEV AKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSG+I+ KQ+Y Sbjct 190 FRSIADEVDAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGMILAKQEY 249 Query 244 AKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVA 303 AK INS+VFPGQQGGPLMH +A KAV++KIA T +F DRQ RTL GA+I+A+RL D Sbjct 250 AKKINSSVFPGQQGGPLMHAVAAKAVSMKIAQTDDFRDRQARTLEGAKILAERLTGQDTV 309 Query 304 KAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLR 363 AGV V++GGTDVHLVLVDLR+S L+GQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLR Sbjct 310 DAGVQVLTGGTDVHLVLVDLRNSELNGQEAEDLLHEVGITVNRNAVPFDPRPPMVTSGLR 369 Query 364 IGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSL 423 IGTPALA+RG FTEVADII TALA G + D +AL+ R ++A FPLY GLE+W L Sbjct 370 IGTPALASRGLDAAAFTEVADIIGTALAQGKNADTAALRARVDKVAADFPLYPGLEDWKL 429 Query 424 V 424 V Sbjct 430 V 430 >gi|269955562|ref|YP_003325351.1| glycine hydroxymethyltransferase [Xylanimonas cellulosilytica DSM 15894] gi|269304243|gb|ACZ29793.1| Glycine hydroxymethyltransferase [Xylanimonas cellulosilytica DSM 15894] Length=428 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/428 (76%), Positives = 361/428 (85%), Gaps = 7/428 (1%) Query 1 MSAP-------LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYA 53 MSAP +A+VDP+IA +L EL RQRDTLEMIASENFVP AVLQAQGSVLTNKYA Sbjct 1 MSAPDPLLTGNIADVDPEIAAVLDGELARQRDTLEMIASENFVPNAVLQAQGSVLTNKYA 60 Query 54 EGLPGRRYYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERL 113 EG PGRRYYGGCE VD+ ENLA RAKALFGAE ANVQPH+GAQANAAVLHAL + G+R+ Sbjct 61 EGYPGRRYYGGCEQVDIAENLAIARAKALFGAEHANVQPHAGAQANAAVLHALATAGDRI 120 Query 114 LGLDLANGGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWS 173 LGL+LA+GGHLTHGM++NFSG+LY+ G YGVDP T+ ++MD VR A+E +P+VIIAGWS Sbjct 121 LGLELAHGGHLTHGMKINFSGRLYDVGSYGVDPQTYRVEMDEVRKKAIEHQPEVIIAGWS 180 Query 174 AYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGR 233 AYPR LDFAAFR IADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVS+TVHKT+GG R Sbjct 181 AYPRHLDFAAFREIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSSTVHKTIGGPR 240 Query 234 SGLIVGKQQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARII 293 SG I+ ++Q+AK I+SAVFPGQQGGPLMHV+A KAVA KIAA+ F DRQ RTL GA+II Sbjct 241 SGFILSQEQWAKKIDSAVFPGQQGGPLMHVVAAKAVAFKIAASESFKDRQERTLRGAQII 300 Query 294 ADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDP 353 A RL PDVA AG SV++GGTDVHLVLVDLR S LDGQ AEDLLH+ GITVNRNAVP DP Sbjct 301 ASRLSEPDVAAAGASVLTGGTDVHLVLVDLRKSALDGQQAEDLLHDAGITVNRNAVPFDP 360 Query 354 RPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFP 413 RPP VTSGLRIGTPALATRGFGD EFTEVADIIA AL G++ DV AL+ R L FP Sbjct 361 RPPRVTSGLRIGTPALATRGFGDAEFTEVADIIAIALRDGAAADVEALRARVDALTAEFP 420 Query 414 LYDGLEEW 421 LYDGL ++ Sbjct 421 LYDGLVQY 428 >gi|227504086|ref|ZP_03934135.1| serine hydroxymethyltransferase [Corynebacterium striatum ATCC 6940] gi|227199320|gb|EEI79368.1| serine hydroxymethyltransferase [Corynebacterium striatum ATCC 6940] Length=433 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/420 (78%), Positives = 356/420 (85%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 + E+DPD+ + E+ RQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEG PGRRYYGG Sbjct 14 MRELDPDVFNAINGEIARQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGG 73 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CEHVDV+E+LARDRAK LFGAEFANVQPHSGAQANAAVL L PG+++LGL LA+GGHL Sbjct 74 CEHVDVIEDLARDRAKELFGAEFANVQPHSGAQANAAVLSTLAEPGDKILGLSLAHGGHL 133 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM+LNFSGKLY+ Y VDP T IDMD +R A++ +PKVIIAGWSAYPR LDFAAF Sbjct 134 THGMKLNFSGKLYDVAAYEVDPETMRIDMDKLREQAIKEQPKVIIAGWSAYPRTLDFAAF 193 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGAKL VDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG RSGLI+ KQ YA Sbjct 194 RSIADEVGAKLWVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGPRSGLILAKQDYA 253 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K INS VFPGQQGGPLMHVIA KA+ALKIAA+ EF RQ RTL GARI+A+RL A D Sbjct 254 KKINSNVFPGQQGGPLMHVIAAKAIALKIAASEEFKKRQERTLEGARILAERLTAADAKA 313 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV V++GGTDVHLVL DLR+S LDGQ AEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI Sbjct 314 AGVDVLTGGTDVHLVLADLRNSELDGQQAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 373 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRG FTEVADII TALA G + DV L+ R ++A +PLYDGLE+W LV Sbjct 374 GTPALATRGLDAAAFTEVADIIGTALAQGKNADVETLRGRVAKIAEQYPLYDGLEDWKLV 433 >gi|260907101|ref|ZP_05915423.1| serine hydroxymethyltransferase [Brevibacterium linens BL2] Length=424 Score = 644 bits (1661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/421 (75%), Positives = 362/421 (86%), Gaps = 2/421 (0%) Query 1 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 60 M A LA++DP IAE+L +ELGRQR TLEMIASENFVPRAVLQAQGSVLTNKYAEG PG+R Sbjct 6 MQASLADIDPQIAEVLDQELGRQRSTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGKR 65 Query 61 YYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLAN 120 YYGGCE+VDV E LA DRAK+LFGAE+ANVQ HSGA ANAAV+HAL G+++LGL LA+ Sbjct 66 YYGGCEYVDVAETLAIDRAKSLFGAEYANVQSHSGASANAAVMHALARQGDKMLGLSLAH 125 Query 121 GGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLD 180 GGHLTHGM++NFSG+LY+ Y VDP T+ IDMD VR ALE RP+VI+AGWSAYPR LD Sbjct 126 GGHLTHGMKINFSGRLYDVASYEVDPDTYRIDMDKVRERALEHRPEVIVAGWSAYPRQLD 185 Query 181 FAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGK 240 F AFR IADEVGAKL VDMAHFAGLVAAGLHP+PVP ADVVS+TVHKT+GG RSG I+GK Sbjct 186 FQAFRDIADEVGAKLWVDMAHFAGLVAAGLHPNPVPFADVVSSTVHKTIGGPRSGFILGK 245 Query 241 QQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAP 300 ++YAK +NSAVFPGQQGGPLMHVIA KAVA K+AA+ EF RQ RT+ GA+I+A+RL+A Sbjct 246 EEYAKKLNSAVFPGQQGGPLMHVIAAKAVAFKLAASEEFKARQERTVRGAQILAERLLAD 305 Query 301 DVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTS 360 DVA AG +V++GGTDVHLVLVDLR+S LDGQ AEDLLHEVGITVNRNAVP DPRPPMVTS Sbjct 306 DVANAGATVLTGGTDVHLVLVDLRNSALDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTS 365 Query 361 GLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEE 420 GLRIGTPALATRGFGD EFTEVAD+IA AL G++V+ AL R +L+ FPLY+ LE+ Sbjct 366 GLRIGTPALATRGFGDAEFTEVADVIAEALKPGANVE--ALSARVKKLSDNFPLYEDLEQ 423 Query 421 W 421 + Sbjct 424 Y 424 >gi|334696511|gb|AEG81308.1| serine hydroxymethyltransferase [Corynebacterium ulcerans 809] Length=429 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/420 (75%), Positives = 359/420 (86%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L+E+DP++A +A EL RQR TLEMIASENFVPRAVLQAQGSV TNKYAEG PGRRYYGG Sbjct 10 LSELDPEVAGAIAGELDRQRSTLEMIASENFVPRAVLQAQGSVFTNKYAEGYPGRRYYGG 69 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+ D+VE+LAR+RAK +FGAEFANVQPH+GAQANAAVL AL +PG++++GL LA+GGHL Sbjct 70 CENADIVEDLARNRAKEVFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLSLAHGGHL 129 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM LNFSGKLYE Y VDP T +DMD VR AL +P+V+IAGWSAYPR DF AF Sbjct 130 THGMHLNFSGKLYEVAAYEVDPETFRVDMDKVREQALAEKPQVLIAGWSAYPRQQDFEAF 189 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGAKL VDMAHFAGLVAA LHPSPVP+ADVVSTTVHKTLGG RSG+I+ KQ+YA Sbjct 190 RSIADEVGAKLWVDMAHFAGLVAADLHPSPVPYADVVSTTVHKTLGGPRSGMILAKQEYA 249 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMH IA KAVA+KIAAT EF +RQ RTL GA++IA+RL++ D Sbjct 250 KKLNSAVFPGQQGGPLMHAIAAKAVAMKIAATEEFKNRQERTLEGAQLIAERLVSADCKA 309 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV V++GGTDVHLVLVDLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLRI Sbjct 310 AGVDVLTGGTDVHLVLVDLRNSQMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLRI 369 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRGF F EVADII TALA G++ +V+ L+ R T+LA +PLY+GLE+W L+ Sbjct 370 GTPALATRGFDTAGFAEVADIIGTALAQGTNANVAELRARVTKLAEQYPLYEGLEDWKLL 429 >gi|337290398|ref|YP_004629419.1| serine hydroxymethyltransferase [Corynebacterium ulcerans BR-AD22] gi|334698704|gb|AEG83500.1| serine hydroxymethyltransferase [Corynebacterium ulcerans BR-AD22] Length=429 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/420 (75%), Positives = 359/420 (86%), Gaps = 0/420 (0%) Query 5 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 64 L+E+DP++A +A EL RQR TLEMIASENFVPRAVLQAQGSV TNKYAEG PGRRYYGG Sbjct 10 LSELDPEVAGAIAGELDRQRSTLEMIASENFVPRAVLQAQGSVFTNKYAEGYPGRRYYGG 69 Query 65 CEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHL 124 CE+ D+VE+LAR+RAK +FGAEFANVQPH+GAQANAAVL AL +PG++++GL LA+GGHL Sbjct 70 CENADIVEDLARNRAKEVFGAEFANVQPHAGAQANAAVLMALANPGDKIMGLSLAHGGHL 129 Query 125 THGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAF 184 THGM LNFSGKLYE Y VDP T +DMD VR AL +P+V+IAGWSAYPR DF AF Sbjct 130 THGMHLNFSGKLYEVAAYEVDPETFRVDMDKVREQALAEKPQVLIAGWSAYPRQQDFEAF 189 Query 185 RSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYA 244 RSIADEVGAKL VDMAHFAGLVAA LHPSPVP+ADVVSTTVHKTLGG RSG+I+ KQ+YA Sbjct 190 RSIADEVGAKLWVDMAHFAGLVAADLHPSPVPYADVVSTTVHKTLGGPRSGMILAKQEYA 249 Query 245 KAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAK 304 K +NSAVFPGQQGGPLMH IA KAVA+KIAAT EF +RQ RTL GA++IA+RL++ D Sbjct 250 KKLNSAVFPGQQGGPLMHAIAAKAVAMKIAATEEFKNRQERTLEGAQLIAERLVSADCKA 309 Query 305 AGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRI 364 AGV V++GGTDVHLVLVDLR+S +DGQ AEDLLHEVGITVNRNAVP DPRPPMVTSGLRI Sbjct 310 AGVDVLTGGTDVHLVLVDLRNSQMDGQQAEDLLHEVGITVNRNAVPFDPRPPMVTSGLRI 369 Query 365 GTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLV 424 GTPALATRGF F EVADII TALA G++ +V+ L+ R T+LA +PLY+GLE+W L+ Sbjct 370 GTPALATRGFDTAGFAEVADIIGTALAQGANANVAELRARVTKLAEQYPLYEGLEDWKLL 429 Lambda K H 0.319 0.136 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 868263609888 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40