BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1106c Length=370 Score E Sequences producing significant alignments: (Bits) Value gi|15608246|ref|NP_215622.1| cholesterol dehydrogenase [Mycobact... 766 0.0 gi|308371866|ref|ZP_07426502.2| cholesterol dehydrogenase [Mycob... 758 0.0 gi|254819706|ref|ZP_05224707.1| 3-beta hydroxysteroid dehydrogen... 660 0.0 gi|336458721|gb|EGO37681.1| nucleoside-diphosphate-sugar epimera... 657 0.0 gi|118466413|ref|YP_880472.1| 3-beta hydroxysteroid dehydrogenas... 656 0.0 gi|41408786|ref|NP_961622.1| hypothetical protein MAP2688 [Mycob... 652 0.0 gi|342861695|ref|ZP_08718341.1| 3-beta hydroxysteroid dehydrogen... 650 0.0 gi|296169972|ref|ZP_06851579.1| possible sterol-4-alpha-carboxyl... 649 0.0 gi|240171095|ref|ZP_04749754.1| putative cholesterol dehydrogena... 643 0.0 gi|183984330|ref|YP_001852621.1| cholesterol dehydrogenase [Myco... 643 0.0 gi|118616065|ref|YP_904397.1| cholesterol dehydrogenase [Mycobac... 640 0.0 gi|15828047|ref|NP_302310.1| cholesterol dehydrogenase [Mycobact... 589 3e-166 gi|120405587|ref|YP_955416.1| 3-beta hydroxysteroid dehydrogenas... 580 1e-163 gi|145222663|ref|YP_001133341.1| 3-beta hydroxysteroid dehydroge... 580 1e-163 gi|108801073|ref|YP_641270.1| 3-beta hydroxysteroid dehydrogenas... 579 3e-163 gi|118469383|ref|YP_889474.1| 3-beta hydroxysteroid dehydrogenas... 578 6e-163 gi|126436911|ref|YP_001072602.1| 3-beta hydroxysteroid dehydroge... 578 7e-163 gi|333989696|ref|YP_004522310.1| cholesterol dehydrogenase [Myco... 570 2e-160 gi|315443126|ref|YP_004076005.1| nucleoside-diphosphate-sugar ep... 568 7e-160 gi|216809|dbj|BAA14290.1| NAD(P)-dependent cholesterol dehydroge... 557 8e-157 gi|289569098|ref|ZP_06449325.1| cholesterol dehydrogenase [Mycob... 496 2e-138 gi|309789742|ref|ZP_07684322.1| hypothetical protein OSCT_0273 [... 202 7e-50 gi|31415898|gb|AAP50919.1| putative 3-beta hydroxysteroid dehydr... 196 6e-48 gi|115453453|ref|NP_001050327.1| Os03g0405000 [Oryza sativa Japo... 196 6e-48 gi|226495071|ref|NP_001150065.1| sterol-4-alpha-carboxylate 3-de... 193 4e-47 gi|148654401|ref|YP_001274606.1| 3-beta hydroxysteroid dehydroge... 190 3e-46 gi|281206047|gb|EFA80236.1| 3beta-hydroxysteroid dehydrogenase [... 189 6e-46 gi|62955325|ref|NP_001017674.1| sterol-4-alpha-carboxylate 3-deh... 188 1e-45 gi|225429728|ref|XP_002282161.1| PREDICTED: hypothetical protein... 187 3e-45 gi|159901211|ref|YP_001547458.1| 3-beta hydroxysteroid dehydroge... 186 4e-45 gi|222056234|ref|YP_002538596.1| 3-beta hydroxysteroid dehydroge... 185 9e-45 gi|297839517|ref|XP_002887640.1| hypothetical protein ARALYDRAFT... 183 4e-44 gi|330801146|ref|XP_003288591.1| 3beta-hydroxysteroid dehydrogen... 183 4e-44 gi|328874398|gb|EGG22763.1| 3beta-hydroxysteroid dehydrogenase [... 182 6e-44 gi|149178706|ref|ZP_01857290.1| hypothetical protein PM8797T_017... 182 6e-44 gi|50753891|ref|XP_414167.1| PREDICTED: hypothetical protein [Ga... 182 6e-44 gi|62859757|ref|NP_001017290.1| NAD(P) dependent steroid dehydro... 182 8e-44 gi|148229598|ref|NP_001090495.1| short-chain dehydrogenase/reduc... 181 1e-43 gi|326927427|ref|XP_003209894.1| PREDICTED: short-chain dehydrog... 181 2e-43 gi|301764697|ref|XP_002917765.1| PREDICTED: short-chain dehydrog... 181 2e-43 gi|255539320|ref|XP_002510725.1| hydroxysteroid dehydrogenase, p... 180 3e-43 gi|224063753|ref|XP_002196863.1| PREDICTED: short chain dehydrog... 180 3e-43 gi|260824135|ref|XP_002607023.1| hypothetical protein BRAFLDRAFT... 179 5e-43 gi|225457644|ref|XP_002275214.1| PREDICTED: hypothetical protein... 179 7e-43 gi|297745599|emb|CBI40764.3| unnamed protein product [Vitis vini... 179 7e-43 gi|147900632|ref|NP_001088890.1| NAD(P) dependent steroid dehydr... 179 9e-43 gi|149918028|ref|ZP_01906521.1| NAD(P)H steroid dehydrogenase [P... 177 2e-42 gi|322419646|ref|YP_004198869.1| 3-beta hydroxysteroid dehydroge... 177 2e-42 gi|197118481|ref|YP_002138908.1| 3-beta-hydroxysteroid dehydroge... 177 2e-42 gi|15226138|ref|NP_180921.1| Rossmann-fold NAD(P)-binding domain... 177 3e-42 >gi|15608246|ref|NP_215622.1| cholesterol dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15840543|ref|NP_335580.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium tuberculosis CDC1551] gi|31792299|ref|NP_854792.1| cholesterol dehydrogenase [Mycobacterium bovis AF2122/97] 71 more sequence titles Length=370 Score = 766 bits (1979), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/370 (100%), Positives = 370/370 (100%), Gaps = 0/370 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL Sbjct 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR Sbjct 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT Sbjct 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV Sbjct 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG Sbjct 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR Sbjct 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 Query 361 AEKTAATVKP 370 AEKTAATVKP Sbjct 361 AEKTAATVKP 370 >gi|308371866|ref|ZP_07426502.2| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu004] gi|308373037|ref|ZP_07430811.2| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu005] gi|308374213|ref|ZP_07435216.2| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu006] gi|308335194|gb|EFP24045.1| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu004] gi|308339000|gb|EFP27851.1| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu005] gi|308342670|gb|EFP31521.1| cholesterol dehydrogenase [Mycobacterium tuberculosis SUMu006] gi|339294101|gb|AEJ46212.1| cholesterol dehydrogenase [Mycobacterium tuberculosis CCDC5079] gi|339297741|gb|AEJ49851.1| cholesterol dehydrogenase [Mycobacterium tuberculosis CCDC5180] Length=366 Score = 758 bits (1958), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/366 (100%), Positives = 366/366 (100%), Gaps = 0/366 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI Sbjct 1 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ Sbjct 61 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR Sbjct 121 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT Sbjct 181 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP Sbjct 241 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 364 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT Sbjct 301 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 360 Query 365 AATVKP 370 AATVKP Sbjct 361 AATVKP 366 >gi|254819706|ref|ZP_05224707.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium intracellulare ATCC 13950] Length=366 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/365 (86%), Positives = 335/365 (92%), Gaps = 0/365 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 M+ RMGDASLT ELGRVLVTGG+GFVG NLVTTLLDRGH VRSFDRAPS LP HPQLEVL Sbjct 1 MISRMGDASLTAELGRVLVTGGSGFVGTNLVTTLLDRGHQVRSFDRAPSPLPEHPQLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITD VCA AVDGIDT+FHTAAII+LMGGASVT+EYRQRSF VNVGGTENL+ AGQ Sbjct 61 QGDITDTAVCARAVDGIDTVFHTAAIIDLMGGASVTEEYRQRSFGVNVGGTENLVRAGQA 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKV+AERFVL QN VDG+LT Sbjct 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVIAERFVLGQNNVDGLLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILAA HLV Sbjct 181 CAIRPSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAQHLV 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P GTAPGQAYFINDAEPINMFEFARPV+EACG+ WP++R++GP VR MTGWQRLHFRFG Sbjct 241 PGGTAPGQAYFINDAEPINMFEFARPVIEACGENWPRVRVNGPVVRAAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDN+FSIAKA RDLGY+PLFTT+QAL+ECLPYYV +FEQMK +A Sbjct 301 IPAPLLEPLAVERLYLDNFFSIAKASRDLGYQPLFTTEQALSECLPYYVGMFEQMKRDAL 360 Query 361 AEKTA 365 K + Sbjct 361 TAKAS 365 >gi|336458721|gb|EGO37681.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium avium subsp. paratuberculosis S397] Length=366 Score = 657 bits (1694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/366 (86%), Positives = 337/366 (93%), Gaps = 0/366 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 M+ MGD SLT ELGRVLVTGG+GFVGANLVTTLL+RG+ VRSFDRAPS LPAHP LEVL Sbjct 1 MIGPMGDPSLTAELGRVLVTGGSGFVGANLVTTLLERGYQVRSFDRAPSPLPAHPHLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA VCAA V+GIDTIFHTAAII+LMGGASVT+EYRQRSFAVNVGGTENL+ AGQ Sbjct 61 QGDITDAGVCAAVVEGIDTIFHTAAIIDLMGGASVTEEYRQRSFAVNVGGTENLVRAGQA 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGVQRFVYTSSNSVVMGGQNI GGDETLPYTDRFNDLYTETKV+AERFVL QNGVDGMLT Sbjct 121 AGVQRFVYTSSNSVVMGGQNIVGGDETLPYTDRFNDLYTETKVLAERFVLGQNGVDGMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILAA HL Sbjct 181 CAIRPSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAQHLT 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 PDGTAPGQAYFINDAEPINMFEFARPV+EACG WP++R++GP VR MTGWQRLHFRFG Sbjct 241 PDGTAPGQAYFINDAEPINMFEFARPVVEACGVNWPRVRVNGPIVRAAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDN+FSIAKA RDLGY+PLFTT+QA++ECLPYYV +FEQMK +A Sbjct 301 IPAPLLEPLAVERLYLDNFFSIAKASRDLGYQPLFTTEQAMSECLPYYVGMFEQMKRQAL 360 Query 361 AEKTAA 366 A K +A Sbjct 361 AGKASA 366 >gi|118466413|ref|YP_880472.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium avium 104] gi|254774110|ref|ZP_05215626.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118167700|gb|ABK68597.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium avium 104] Length=366 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/366 (86%), Positives = 337/366 (93%), Gaps = 0/366 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 M+ MGD SLT ELGRVLVTGG+GFVGANLVTTLL+RG+ VRSFDRAPS LPAHP LEVL Sbjct 1 MIGPMGDPSLTAELGRVLVTGGSGFVGANLVTTLLERGYQVRSFDRAPSPLPAHPHLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA VCAAAV+GIDTIFHTAAII+LMGGASVT+EYRQRSFAVNVGGTENL+ AGQ Sbjct 61 QGDITDAGVCAAAVEGIDTIFHTAAIIDLMGGASVTEEYRQRSFAVNVGGTENLVRAGQA 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGVQRFVYTSSNSVVMGGQNI GGDETLPYTDRFNDLYTETKV+AERFVL QNGVDGMLT Sbjct 121 AGVQRFVYTSSNSVVMGGQNIVGGDETLPYTDRFNDLYTETKVLAERFVLGQNGVDGMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILAA HL Sbjct 181 CAIRPSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAQHLT 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P GTAPGQAYFINDAEPINMFEFARPV+EACG WP++R++GP VR MTGWQRLHFRFG Sbjct 241 PGGTAPGQAYFINDAEPINMFEFARPVVEACGVNWPRVRVNGPIVRAAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDN+FSIAKA RDLGY+PLFTT+QA++ECLPYYV +FEQMK +A Sbjct 301 IPAPLLEPLAVERLYLDNFFSIAKASRDLGYQPLFTTEQAMSECLPYYVGMFEQMKRQAL 360 Query 361 AEKTAA 366 A K +A Sbjct 361 AGKASA 366 >gi|41408786|ref|NP_961622.1| hypothetical protein MAP2688 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397144|gb|AAS05005.1| hypothetical protein MAP_2688 [Mycobacterium avium subsp. paratuberculosis K-10] Length=366 Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/366 (85%), Positives = 335/366 (92%), Gaps = 0/366 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 M+ MGD SLT ELGRVLVTGG+GFVGANLVTTLL+RG+ VRSFDRAPS LPAHP LEVL Sbjct 1 MIGPMGDPSLTAELGRVLVTGGSGFVGANLVTTLLERGYQVRSFDRAPSPLPAHPHLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA VCAA V+GIDTIFHTAAII+LMGGASVT+EYRQRSFAVNVGGTENL+ AGQ Sbjct 61 QGDITDAGVCAAVVEGIDTIFHTAAIIDLMGGASVTEEYRQRSFAVNVGGTENLVRAGQA 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGVQRFVYTSSNSVVMGGQNI GGDETLPYTDRFNDLYTETKV+AERFVL QNGVDGMLT Sbjct 121 AGVQRFVYTSSNSVVMGGQNIVGGDETLPYTDRFNDLYTETKVLAERFVLGQNGVDGMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILA HL Sbjct 181 CAIRPSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILADQHLT 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P GTAPGQAYFINDAEPINMFEFARPV+EACG WP++R++GP VR MTGWQRLHFRFG Sbjct 241 PGGTAPGQAYFINDAEPINMFEFARPVVEACGVNWPRVRVNGPIVRAAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDN+FSIAKA RDLGY+PLFTT+QA++ECLPYYV +FEQMK +A Sbjct 301 IPAPLLEPLAVERLYLDNFFSIAKASRDLGYQPLFTTEQAMSECLPYYVGMFEQMKRQAL 360 Query 361 AEKTAA 366 A K +A Sbjct 361 AGKASA 366 >gi|342861695|ref|ZP_08718341.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium colombiense CECT 3035] gi|342130829|gb|EGT84125.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium colombiense CECT 3035] Length=362 Score = 650 bits (1676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/362 (86%), Positives = 331/362 (92%), Gaps = 0/362 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 MGDASLT ELGRVLVTGG+GFVGANLVTTLLDRGH VRSFDRAPS LP HP+LEVLQGDI Sbjct 1 MGDASLTAELGRVLVTGGSGFVGANLVTTLLDRGHQVRSFDRAPSPLPPHPRLEVLQGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 TD VCA AVDGIDT+FHTAAII+LMGGASVTDEYRQRSF VNVGGTENL+ AGQ AGVQ Sbjct 61 TDTAVCAQAVDGIDTVFHTAAIIDLMGGASVTDEYRQRSFGVNVGGTENLVRAGQAAGVQ 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYTSSNSVVMGGQNI GDETLPYT RFNDLYTETKV+AERFVL QNGVDG+LTCAIR Sbjct 121 RFVYTSSNSVVMGGQNIVNGDETLPYTTRFNDLYTETKVIAERFVLGQNGVDGLLTCAIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILAA HL P GT Sbjct 181 PSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAEHLTPGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFINDAEPINMFEFARPV+EACG++WP++R++GP VR MTGWQRLHFRFG PAP Sbjct 241 APGQAYFINDAEPINMFEFARPVVEACGEKWPRVRVNGPIVRAAMTGWQRLHFRFGIPAP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 364 LLEPLAVERLYLDN+FSIAKA RDLGY+PLF T+QALTECL YYV +F+QMK +A A K Sbjct 301 LLEPLAVERLYLDNFFSIAKASRDLGYQPLFNTEQALTECLSYYVDMFDQMKRQALAGKA 360 Query 365 AA 366 +A Sbjct 361 SA 362 >gi|296169972|ref|ZP_06851579.1| possible sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895376|gb|EFG75082.1| possible sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) [Mycobacterium parascrofulaceum ATCC BAA-614] Length=368 Score = 649 bits (1674), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/364 (86%), Positives = 333/364 (92%), Gaps = 0/364 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 M DA+LTTELGRVLVTGG+GFVGANLVTTLLDRG+ VRSFDRAPS L H QLEVL+GDI Sbjct 1 MSDAALTTELGRVLVTGGSGFVGANLVTTLLDRGYRVRSFDRAPSPLAEHRQLEVLEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 TD VCA AVDG+DTIFHTAAIIELMGGASVTD YRQRSFAVNVGGTENL+HAGQ AGVQ Sbjct 61 TDTAVCARAVDGVDTIFHTAAIIELMGGASVTDAYRQRSFAVNVGGTENLVHAGQAAGVQ 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYTSSNSVVMGGQNI GGDETLPYTDRFNDLYTETKVVAERFVLAQNG+ GMLTCAIR Sbjct 121 RFVYTSSNSVVMGGQNIPGGDETLPYTDRFNDLYTETKVVAERFVLAQNGIGGMLTCAIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRKLFESV+ GHVKVL+GRKSARLDNSYVHNLIHGFILAA HLVP GT Sbjct 181 PSGIWGRGDQTMFRKLFESVIAGHVKVLIGRKSARLDNSYVHNLIHGFILAAQHLVPGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFIND EPINMFEFARPV+EACG WP++R++GP VR MTGWQRLHFRFG PAP Sbjct 241 APGQAYFINDDEPINMFEFARPVVEACGVNWPRVRVNGPLVRVAMTGWQRLHFRFGIPAP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 364 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTT+QA+++CLPYYV +F++MK++A E T Sbjct 301 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTEQAMSQCLPYYVDMFQRMKSQAEVEST 360 Query 365 AATV 368 V Sbjct 361 RPAV 364 >gi|240171095|ref|ZP_04749754.1| putative cholesterol dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=373 Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/360 (86%), Positives = 330/360 (92%), Gaps = 0/360 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 MLRRMGDASLTTELGRVLVTGG+GFVGANLVTTLL+RG+ VRSFDRAPS LP HP+LEVL Sbjct 1 MLRRMGDASLTTELGRVLVTGGSGFVGANLVTTLLERGYQVRSFDRAPSPLPPHPKLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA CA AVDGIDTIFHTAAIIELMGGASVTDEYR+RSFAVNVGGTENL+H GQR Sbjct 61 QGDITDAATCATAVDGIDTIFHTAAIIELMGGASVTDEYRKRSFAVNVGGTENLVHGGQR 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGV+RFVYTSSNSVVMGGQNIAGGDET+PYT RFNDLYTETKV AERFVL+QNGVDGMLT Sbjct 121 AGVKRFVYTSSNSVVMGGQNIAGGDETMPYTSRFNDLYTETKVAAERFVLSQNGVDGMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQTMFRKLFESV+KG VKVLVGRKSARLDNSYV NLIHGFILAA HLV Sbjct 181 CAIRPSGIWGRGDQTMFRKLFESVVKGQVKVLVGRKSARLDNSYVDNLIHGFILAAQHLV 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P GTAPGQAYFINDAEPINMFEFARPV+ ACG+ WP++R+SG VR +M+ WQ LHFRFG Sbjct 241 PGGTAPGQAYFINDAEPINMFEFARPVVTACGESWPRIRVSGRLVRDLMSAWQWLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 P P LEPLAVERLYLDNYFSIAKA+RDLGY PLFTT+QAL ECLPYY LFEQ+K A+ Sbjct 301 LPKPPLEPLAVERLYLDNYFSIAKAQRDLGYRPLFTTEQALAECLPYYKDLFEQVKAAAK 360 >gi|183984330|ref|YP_001852621.1| cholesterol dehydrogenase [Mycobacterium marinum M] gi|183177656|gb|ACC42766.1| cholesterol dehydrogenase [Mycobacterium marinum M] Length=364 Score = 643 bits (1658), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/361 (85%), Positives = 331/361 (92%), Gaps = 0/361 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 MLR MGDASLTTELGRVLVTGG+GFVG+NLVTTLLDRGH VRSFDRAPS LP HPQLEVL Sbjct 1 MLRPMGDASLTTELGRVLVTGGSGFVGSNLVTTLLDRGHHVRSFDRAPSPLPPHPQLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA CA AVDG+DT+FHTAAIIELMGGASVTDEYR+RSF+VNVGGTENL+ GQ+ Sbjct 61 QGDITDAATCATAVDGVDTVFHTAAIIELMGGASVTDEYRKRSFSVNVGGTENLVREGQQ 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGV+RFVYTSSNSVVMGGQ IAGGDETLPYT+RFNDLYTETKVVAE+FVL+QNG + MLT Sbjct 121 AGVKRFVYTSSNSVVMGGQIIAGGDETLPYTNRFNDLYTETKVVAEKFVLSQNGNNEMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQ MFRKLFESV+KGHVKVLVG KSA LDNSYV NLIHGFILAA HLV Sbjct 181 CAIRPSGIWGTGDQLMFRKLFESVIKGHVKVLVGPKSALLDNSYVDNLIHGFILAAQHLV 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P G+APGQAYFINDAEPINMFEFARPV+EACG++WP++R+SGP V MTGWQRLHFRFG Sbjct 241 PGGSAPGQAYFINDAEPINMFEFARPVVEACGEKWPRVRVSGPMVHRAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDNYFS+ KARRDLGYEP FTT+QAL ECLPYYV LF QMK+E + Sbjct 301 LPAPLLEPLAVERLYLDNYFSVDKARRDLGYEPKFTTEQALKECLPYYVDLFRQMKSEVK 360 Query 361 A 361 A Sbjct 361 A 361 >gi|118616065|ref|YP_904397.1| cholesterol dehydrogenase [Mycobacterium ulcerans Agy99] gi|118568175|gb|ABL02926.1| cholesterol dehydrogenase [Mycobacterium ulcerans Agy99] Length=364 Score = 640 bits (1651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/361 (85%), Positives = 331/361 (92%), Gaps = 0/361 (0%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 MLR MGDASLTTELGRVLVTGG+GFVG+NLVTTLLDRGH VRSFDRAPS LP HPQLEVL Sbjct 1 MLRPMGDASLTTELGRVLVTGGSGFVGSNLVTTLLDRGHHVRSFDRAPSPLPPHPQLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA CA AVDG+DT+FHTAAIIELMGGASVTDEYR+RSF+VNVGGTENL+ AGQ+ Sbjct 61 QGDITDAATCATAVDGVDTVFHTAAIIELMGGASVTDEYRKRSFSVNVGGTENLVRAGQQ 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLT 180 AGV+RFVYTSSNSVVMGGQ IAGGDETLPYT+RFNDLYTETKVVAE+FVL+QNG + MLT Sbjct 121 AGVKRFVYTSSNSVVMGGQIIAGGDETLPYTNRFNDLYTETKVVAEKFVLSQNGNNEMLT 180 Query 181 CAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLV 240 CAIRPSGIWG GDQ MFRKLFESV+KGHVKVLVG KS LDNSYV NLIHGF+LAA HLV Sbjct 181 CAIRPSGIWGTGDQLMFRKLFESVIKGHVKVLVGPKSVLLDNSYVDNLIHGFMLAAQHLV 240 Query 241 PDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFG 300 P G+APGQAYFINDAEPINMF+FARPV+EACG++WP++R+SGP V MTGWQRLHFRFG Sbjct 241 PGGSAPGQAYFINDAEPINMFDFARPVVEACGEKWPRVRVSGPMVHRAMTGWQRLHFRFG 300 Query 301 FPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PAPLLEPLAVERLYLDNYFS+ KARRDLGYEP FTT+QAL ECLPYYV LF QMK+E + Sbjct 301 LPAPLLEPLAVERLYLDNYFSVDKARRDLGYEPKFTTEQALKECLPYYVDLFRQMKSEVK 360 Query 361 A 361 A Sbjct 361 A 361 >gi|15828047|ref|NP_302310.1| cholesterol dehydrogenase [Mycobacterium leprae TN] gi|221230524|ref|YP_002503940.1| putative cholesterol dehydrogenase [Mycobacterium leprae Br4923] gi|4539098|emb|CAB39816.1| putative cholesterol dehydrogenase [Mycobacterium leprae] gi|13093600|emb|CAC30897.1| probable cholesterol dehydrogenase [Mycobacterium leprae] gi|219933631|emb|CAR72039.1| probable cholesterol dehydrogenase [Mycobacterium leprae Br4923] Length=376 Score = 589 bits (1518), Expect = 3e-166, Method: Compositional matrix adjust. Identities = 283/375 (76%), Positives = 320/375 (86%), Gaps = 5/375 (1%) Query 1 MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL 60 MLR +G+ASLTTELGRVLVTGG+GFVGANLVT LL+RG+ VRSFDRAP LP HPQLEVL Sbjct 1 MLRGVGNASLTTELGRVLVTGGSGFVGANLVTALLERGYQVRSFDRAPMPLPQHPQLEVL 60 Query 61 QGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQR 120 QGDITDA VC A+D IDT+FHTAAIIELMGGASVTDEYRQRS+ VNVGGTENLL AGQ+ Sbjct 61 QGDITDATVCTTAMDSIDTVFHTAAIIELMGGASVTDEYRQRSYTVNVGGTENLLRAGQK 120 Query 121 AGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGV-DG-- 177 +GV+RFVYT+SNSVVMGG I GGDET+PYT RFNDLYTETKVVAE+FVL+QNGV DG Sbjct 121 SGVKRFVYTASNSVVMGGTPITGGDETMPYTKRFNDLYTETKVVAEKFVLSQNGVPDGET 180 Query 178 MLTCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAA 237 MLTC+IRPSGIWG GDQTMFRK FESV+ GHVKVL+G K+A+LDNSYVHNL+HG ILAA Sbjct 181 MLTCSIRPSGIWGRGDQTMFRKAFESVVSGHVKVLIGSKNAKLDNSYVHNLVHGLILAAE 240 Query 238 HLVPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHF 297 HLVP GTAPGQAYFIND EPIN F+F P+++ACG+ WP++RISG VR VM WQRLHF Sbjct 241 HLVPGGTAPGQAYFINDGEPINFFDFMGPIIKACGENWPRVRISGRLVRNVMAVWQRLHF 300 Query 298 RFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKN 357 FG P P +EPLAVER+YLDNYFSI KA ++LGY PLFTT+QA+ ECLPYY LFEQ+K Sbjct 301 GFGLPKPPMEPLAVERVYLDNYFSIEKAHKELGYRPLFTTEQAMAECLPYYTELFEQIKV 360 Query 358 EARAE--KTAATVKP 370 A+ AAT +P Sbjct 361 AAKPHLASIAATPRP 375 >gi|120405587|ref|YP_955416.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium vanbaalenii PYR-1] gi|119958405|gb|ABM15410.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium vanbaalenii PYR-1] Length=375 Score = 580 bits (1496), Expect = 1e-163, Method: Compositional matrix adjust. Identities = 284/359 (80%), Positives = 310/359 (87%), Gaps = 5/359 (1%) Query 5 MGDASL-TTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGD 63 MGDA+ TTELGRVLVTGG+GFVGANLVT LLDRG VRSFDR PS LP HP LEV+QGD Sbjct 1 MGDATTPTTELGRVLVTGGSGFVGANLVTELLDRGLQVRSFDRVPSPLPDHPGLEVVQGD 60 Query 64 ITDADVCAAAV----DGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQ 119 ITD D A AV D DT+FHTAAII+LMGGASVT+EYRQRSFAVNV GT+NL+HA Q Sbjct 61 ITDVDDVARAVGTGADKADTVFHTAAIIDLMGGASVTEEYRQRSFAVNVTGTKNLVHAAQ 120 Query 120 RAGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGML 179 +AGVQRFVYT+SNSVVMGGQ IAGGDETLPYT+RFNDLYTETKVVAE+FVL+QNGV GML Sbjct 121 KAGVQRFVYTASNSVVMGGQRIAGGDETLPYTERFNDLYTETKVVAEKFVLSQNGVSGML 180 Query 180 TCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHL 239 TC+IRPSGIWG GDQTMFRK+FESVL GHVKVLVG K+ +LDNSYVHNL+HGFILAA HL Sbjct 181 TCSIRPSGIWGRGDQTMFRKVFESVLAGHVKVLVGNKNVKLDNSYVHNLVHGFILAAQHL 240 Query 240 VPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRF 299 V GTAPGQAYFIND EPINMFEFARPV+EACG+ WP R+SG V + MT WQ LHFRF Sbjct 241 VDGGTAPGQAYFINDGEPINMFEFARPVMEACGEPWPTFRVSGRLVWFAMTIWQFLHFRF 300 Query 300 GFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNE 358 G P PLLEPLAVERLYLDNYFSIAKA RDLGY PL+TT+QAL C+PYYV LF +MK E Sbjct 301 GLPKPLLEPLAVERLYLDNYFSIAKAERDLGYRPLYTTEQALEHCIPYYVDLFGRMKAE 359 >gi|145222663|ref|YP_001133341.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium gilvum PYR-GCK] gi|145215149|gb|ABP44553.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium gilvum PYR-GCK] Length=366 Score = 580 bits (1495), Expect = 1e-163, Method: Compositional matrix adjust. Identities = 274/350 (79%), Positives = 312/350 (90%), Gaps = 0/350 (0%) Query 10 LTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADV 69 L TELGRVLVTGG+GFVGANLVT LLDRG VRSFDR S LPAH +LE+++GDITDAD Sbjct 2 LRTELGRVLVTGGSGFVGANLVTELLDRGLHVRSFDRVASALPAHARLEIVEGDITDADD 61 Query 70 CAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYT 129 AAAV+G+DT+FHTAAII+LMGGASV++EYRQRSFAVNV GT+NL+HA Q+AGV RFVYT Sbjct 62 VAAAVEGVDTVFHTAAIIDLMGGASVSEEYRQRSFAVNVTGTQNLVHAAQKAGVTRFVYT 121 Query 130 SSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIW 189 +SNSVVMGGQ IAGGDETLPYT+RFNDLYTETKVVAE+FVL+QNGV G+LTC+IRPSGIW Sbjct 122 ASNSVVMGGQRIAGGDETLPYTERFNDLYTETKVVAEKFVLSQNGVSGLLTCSIRPSGIW 181 Query 190 GNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQA 249 G GDQTMFRK+FESVL GHVKVLVG K +LDNSYVHNL+HGFILAA HLV G+APGQA Sbjct 182 GRGDQTMFRKVFESVLAGHVKVLVGNKETKLDNSYVHNLVHGFILAAEHLVEGGSAPGQA 241 Query 250 YFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPL 309 YFIND EPINMFEFARPV++ACG+ +PK R+ G V + MT WQ LHF+FG P PLLEPL Sbjct 242 YFINDGEPINMFEFARPVVQACGEPFPKFRVPGRLVWFAMTIWQFLHFKFGLPKPLLEPL 301 Query 310 AVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEA 359 AVERLYLDNYFSIAKA+RDLGY+PLFTT+QAL +C+PYYV LF++MK EA Sbjct 302 AVERLYLDNYFSIAKAQRDLGYQPLFTTEQALAQCIPYYVELFDRMKREA 351 >gi|108801073|ref|YP_641270.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. MCS] gi|119870215|ref|YP_940167.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. KMS] gi|108771492|gb|ABG10214.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. MCS] gi|119696304|gb|ABL93377.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. KMS] Length=371 Score = 579 bits (1492), Expect = 3e-163, Method: Compositional matrix adjust. Identities = 282/362 (78%), Positives = 319/362 (89%), Gaps = 2/362 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 M DA+LTTELGRVLVTGG+GFVGANLVT LL+RGH VRSFDRAPS LP HP LE L+GDI Sbjct 1 MADATLTTELGRVLVTGGSGFVGANLVTELLERGHHVRSFDRAPSPLPPHPLLETLEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 D + AAAV G+DT+FHTAAII+LMGGASVTDEYR+RSFAVNVGGTENL+ AG+ AGV+ Sbjct 61 CDPETVAAAVAGVDTVFHTAAIIDLMGGASVTDEYRRRSFAVNVGGTENLVRAGRAAGVK 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYT+SNSVVMGGQ I GDETLPYTDRFNDLYTETKV AE++VLAQNG+DGMLTC+IR Sbjct 121 RFVYTASNSVVMGGQPIVAGDETLPYTDRFNDLYTETKVAAEKYVLAQNGIDGMLTCSIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRK+FESVL GHVKVLVG K+ +LDNSYVHNLIHGFILAA HLVP GT Sbjct 181 PSGIWGRGDQTMFRKVFESVLAGHVKVLVGSKNVKLDNSYVHNLIHGFILAAEHLVPGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFIND EP+NMFEF+RPV+EACG+R+P++R+ G V +VMT WQ+LHFRFG P P Sbjct 241 APGQAYFINDGEPVNMFEFSRPVVEACGERYPRLRVPGRLVHFVMTVWQKLHFRFGLPKP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 364 LLEPL+VER+YLDN+FSIAKA RDLGY PLFTT+QA+ CLPYYV L+E+MK A KT Sbjct 301 LLEPLSVERIYLDNHFSIAKAERDLGYRPLFTTEQAMQACLPYYVELYEKMK--ADGAKT 358 Query 365 AA 366 A Sbjct 359 PA 360 >gi|118469383|ref|YP_889474.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium smegmatis str. MC2 155] gi|118170670|gb|ABK71566.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium smegmatis str. MC2 155] Length=356 Score = 578 bits (1489), Expect = 6e-163, Method: Compositional matrix adjust. Identities = 275/353 (78%), Positives = 307/353 (87%), Gaps = 0/353 (0%) Query 8 ASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDA 67 A TT+LGR+LVTGG+GFVGANLVT LLDRG+ VRSFDR PS LPAH LEV GDI D Sbjct 2 ADSTTDLGRILVTGGSGFVGANLVTELLDRGYAVRSFDRVPSPLPAHAGLEVATGDICDL 61 Query 68 DVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFV 127 D AV G+DT+FHTAAII+LMGGASVT EYRQRSFAVNVGGTENL+ A Q AGV+RFV Sbjct 62 DNVTNAVAGVDTVFHTAAIIDLMGGASVTAEYRQRSFAVNVGGTENLVRAAQSAGVKRFV 121 Query 128 YTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSG 187 YT+SNSVVMGGQ+I GDETLPYT+RFNDLYTETKVVAE+FVL +NGV GMLTC+IRPSG Sbjct 122 YTASNSVVMGGQHIVHGDETLPYTERFNDLYTETKVVAEKFVLGRNGVAGMLTCSIRPSG 181 Query 188 IWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPG 247 IWG GDQTMFRK+FESVL GHVKVLVGRKS LDNSYVHNL+HGFILAA HL P+GTAPG Sbjct 182 IWGRGDQTMFRKVFESVLAGHVKVLVGRKSTLLDNSYVHNLVHGFILAAEHLTPNGTAPG 241 Query 248 QAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLE 307 QAYFIND EP+NMFEFARPV+EACG++ P++R+ G AV M+GWQRLHFRFG P PLLE Sbjct 242 QAYFINDGEPVNMFEFARPVIEACGRKLPRVRVPGRAVHAAMSGWQRLHFRFGIPEPLLE 301 Query 308 PLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEAR 360 PLAVERLYL+NYFSIAKA RDLGY PLFTT+QA +CLPYYV LF+QM+ +AR Sbjct 302 PLAVERLYLNNYFSIAKATRDLGYRPLFTTEQARVDCLPYYVDLFKQMEAQAR 354 >gi|126436911|ref|YP_001072602.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. JLS] gi|126236711|gb|ABO00112.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium sp. JLS] Length=371 Score = 578 bits (1489), Expect = 7e-163, Method: Compositional matrix adjust. Identities = 282/362 (78%), Positives = 318/362 (88%), Gaps = 2/362 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 M DA+LTTELGRVLVTGG+GFVGANLVT LL+RGH VRSFDRAPS LP HP LE L+GDI Sbjct 1 MADATLTTELGRVLVTGGSGFVGANLVTELLERGHHVRSFDRAPSPLPPHPLLETLEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 D + AAAV G+DT+FHTAAII+LMGGASVTDEYR+RSFAVNVGGTENL+ AG+ AGV+ Sbjct 61 CDPETVAAAVAGVDTVFHTAAIIDLMGGASVTDEYRRRSFAVNVGGTENLVRAGRAAGVK 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYT+SNSVVMGGQ I GDETLPYTDRFNDLYTETKV AE++VLAQNG+DGMLTC+IR Sbjct 121 RFVYTASNSVVMGGQPIVAGDETLPYTDRFNDLYTETKVAAEKYVLAQNGIDGMLTCSIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRK+FESVL GHVKVLVG K+ +LDNSYVHNLIHGFILAA HLVP GT Sbjct 181 PSGIWGRGDQTMFRKVFESVLAGHVKVLVGSKNVKLDNSYVHNLIHGFILAAEHLVPGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFIND EP+NMFEF+RPV+EACG+R+P++R+ G V +VMT WQ+LHFRFG P P Sbjct 241 APGQAYFINDGEPVNMFEFSRPVVEACGERYPRLRVPGRLVHFVMTVWQQLHFRFGLPKP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKT 364 LLEPL VER+YLDN+FSIAKA RDLGY PLFTT+QA+ CLPYYV L+E+MK A KT Sbjct 301 LLEPLGVERIYLDNHFSIAKAERDLGYRPLFTTEQAMQACLPYYVELYEKMK--ADGAKT 358 Query 365 AA 366 A Sbjct 359 PA 360 >gi|333989696|ref|YP_004522310.1| cholesterol dehydrogenase [Mycobacterium sp. JDM601] gi|333485664|gb|AEF35056.1| cholesterol dehydrogenase [Mycobacterium sp. JDM601] Length=372 Score = 570 bits (1468), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 273/369 (74%), Positives = 309/369 (84%), Gaps = 3/369 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 MGD SLTTELGRVLVTGG+GFVG N V TLLD+G+ VRSFDRA S LP HP L+ L+GDI Sbjct 1 MGDPSLTTELGRVLVTGGSGFVGTNFVKTLLDQGYQVRSFDRASSPLPDHPGLQKLEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 D A AV IDT+FHTAAII+L GGA VTDE R+RSFAVNV GT NL+ AGQRAGV+ Sbjct 61 CDPQTVAQAVTDIDTVFHTAAIIDLQGGAKVTDEIRRRSFAVNVDGTRNLVQAGQRAGVK 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGV---DGMLTC 181 RFVYT+SNSVVMGG+ I+GGDE + YT +FNDLYTETKVVAE+FVL +NG GMLTC Sbjct 121 RFVYTASNSVVMGGKAISGGDENMAYTTKFNDLYTETKVVAEKFVLGENGGRDGQGMLTC 180 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 +IRPSGIWGNGDQTMFRKLFESV+ GHVKVL+G K+A+LDNSYVHNLIHGFILAA HLVP Sbjct 181 SIRPSGIWGNGDQTMFRKLFESVVAGHVKVLIGSKNAKLDNSYVHNLIHGFILAAQHLVP 240 Query 242 DGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGF 301 GTAPGQAYF+ND EPINMFEFARPV+EACG+RWP++R+SG VR VM WQ LHFRFGF Sbjct 241 GGTAPGQAYFVNDGEPINMFEFARPVMEACGERWPRLRVSGRVVRDVMVAWQWLHFRFGF 300 Query 302 PAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARA 361 P PLLEP AVERLYL+NYFSI KARRDLGY+PLFTT+QA+T+CLPYY LFE++K EA Sbjct 301 PQPLLEPGAVERLYLNNYFSIDKARRDLGYQPLFTTEQAMTDCLPYYKELFERVKAEAHP 360 Query 362 EKTAATVKP 370 +P Sbjct 361 HLATVVAEP 369 >gi|315443126|ref|YP_004076005.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] gi|315261429|gb|ADT98170.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] Length=370 Score = 568 bits (1463), Expect = 7e-160, Method: Compositional matrix adjust. Identities = 276/355 (78%), Positives = 315/355 (89%), Gaps = 0/355 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 MGDA+L T+LGRVLVTGG+GFVGANLVT LL+RG VRSFDR S LPAH +LE+ +GDI Sbjct 1 MGDATLRTDLGRVLVTGGSGFVGANLVTELLERGLHVRSFDRVASALPAHARLEIFEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 TDAD AAAVDGIDT+FHTAAII+LMGGASVT+EYRQRSFAVNV GT+NL+HA Q+AG + Sbjct 61 TDADDVAAAVDGIDTVFHTAAIIDLMGGASVTEEYRQRSFAVNVTGTQNLVHAAQKAGAK 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYT+SNSVVMGGQ IAGGDETLPYT+RFNDLYTETKVVAE+FVL+QNG+ GMLTC+IR Sbjct 121 RFVYTASNSVVMGGQRIAGGDETLPYTERFNDLYTETKVVAEKFVLSQNGISGMLTCSIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRK+FESVL GHVKVLVG ++ +LDNSYVHNL+HGFILAA HLV GT Sbjct 181 PSGIWGRGDQTMFRKVFESVLAGHVKVLVGNENVKLDNSYVHNLVHGFILAAEHLVDGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFIND EPINMFEFARPV+EACG+ +P+ R+ G V + MT WQ LHF+FG P P Sbjct 241 APGQAYFINDGEPINMFEFARPVVEACGEPFPRFRVPGRLVWFAMTIWQFLHFKFGLPKP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEA 359 LLEPLAVERLYLDNYFSIAKA+RDLGY+P FTT+QAL +C+PYYV LF++MK E Sbjct 301 LLEPLAVERLYLDNYFSIAKAQRDLGYQPRFTTEQALEQCIPYYVELFDRMKREG 355 >gi|216809|dbj|BAA14290.1| NAD(P)-dependent cholesterol dehydrogenase [Nocardia sp.] Length=364 Score = 557 bits (1436), Expect = 8e-157, Method: Compositional matrix adjust. Identities = 267/353 (76%), Positives = 300/353 (85%), Gaps = 0/353 (0%) Query 5 MGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDI 64 MGDASLTT+LG VLVTGG+GFVGANLVT LLDRG+ VRSFDRAPS L H LEV++GDI Sbjct 1 MGDASLTTDLGCVLVTGGSGFVGANLVTELLDRGYAVRSFDRAPSPLGDHAGLEVIEGDI 60 Query 65 TDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQ 124 D + AAAV IDT+ HTAAII+LMGGASVT+ YRQRSFAVNV GT+NL+HA Q AGV+ Sbjct 61 CDKETVAAAVKDIDTVIHTAAIIDLMGGASVTEAYRQRSFAVNVEGTKNLVHASQEAGVK 120 Query 125 RFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIR 184 RFVYT+SNSVVMGGQ+I GDET+PYT RFNDLYTETKVVAE+FVLA+NG MLTCAIR Sbjct 121 RFVYTASNSVVMGGQDIVNGDETMPYTTRFNDLYTETKVVAEKFVLAENGKHDMLTCAIR 180 Query 185 PSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT 244 PSGIWG GDQTMFRK+FE+VL GHVKVLVG K+ +LDNSYVHNLIHGFILA LVP GT Sbjct 181 PSGIWGRGDQTMFRKVFENVLAGHVKVLVGNKNIKLDNSYVHNLIHGFILAGQDLVPGGT 240 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAP 304 APGQAYFIND EPINMFEFARPVL ACG+ P +SG V VM WQ LHF+F P P Sbjct 241 APGQAYFINDGEPINMFEFARPVLAACGRPLPTFYVSGRLVHKVMMAWQWLHFKFALPEP 300 Query 305 LLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKN 357 L+EPLAVERLYL+NYFSIAKA+RDLGYEPLFTT+QA+ EC+PYYV +F QM++ Sbjct 301 LIEPLAVERLYLNNYFSIAKAKRDLGYEPLFTTEQAMAECMPYYVEMFHQMES 353 >gi|289569098|ref|ZP_06449325.1| cholesterol dehydrogenase [Mycobacterium tuberculosis T17] gi|289542852|gb|EFD46500.1| cholesterol dehydrogenase [Mycobacterium tuberculosis T17] Length=236 Score = 496 bits (1278), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 235/236 (99%), Positives = 236/236 (100%), Gaps = 0/236 (0%) Query 135 VMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQ 194 +MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQ Sbjct 1 MMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQ 60 Query 195 TMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIND 254 TMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIND Sbjct 61 TMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIND 120 Query 255 AEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERL 314 AEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERL Sbjct 121 AEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERL 180 Query 315 YLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP 370 YLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP Sbjct 181 YLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP 236 >gi|309789742|ref|ZP_07684322.1| hypothetical protein OSCT_0273 [Oscillochloris trichoides DG6] gi|308228228|gb|EFO81876.1| hypothetical protein OSCT_0273 [Oscillochloris trichoides DG6] Length=334 Score = 202 bits (514), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 125/334 (38%), Positives = 177/334 (53%), Gaps = 13/334 (3%) Query 10 LTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADV 69 + + G+ LV GGAGFVG ++V LL GH VR FDR P +PQ+E GD+ D Sbjct 1 MAAKAGKSLVIGGAGFVGRHIVAALLQAGHAVRVFDRVPI---QNPQVEDWVGDLRDPAA 57 Query 70 CAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYT 129 A A G+DT++ +A+++E+ G + ++ +AVNV G +++ AGVQR +YT Sbjct 58 VAEACRGVDTVYQSASLVEVRPG------HAEQLYAVNVYGNRHVIAGCVAAGVQRLIYT 111 Query 130 SSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIW 189 SS VV G+ I GDE LPY R D Y TK++AER VL NG G+ TCA+R +G++ Sbjct 112 SSIDVVFSGRPIRNGDEDLPYPTRHMDTYGRTKMLAEREVLHANGRGGLATCALRLAGVY 171 Query 190 GNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQA 249 G GD F + + + + + V +G +R ++ YV N+ + +LAA HL G Sbjct 172 GPGDNHRFPAVLD-LARANRGVRLGDGRSRFNHVYVENVAYAHLLAAEHLRLGSPIAGAN 230 Query 250 YFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHF---RFGFPAPLL 306 YFI D P N F F P L G P I + T ++ R AP L Sbjct 231 YFIIDHPPENFFTFFDPFLHDLGLPLPTRSIPYRTAYLLATAFELFSLTAGRLLAAAPPL 290 Query 307 EPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQA 340 V LD +FS +ARRDLGY P + ++A Sbjct 291 TRYTVASTCLDFFFSGERARRDLGYSPPISAEEA 324 >gi|31415898|gb|AAP50919.1| putative 3-beta hydroxysteroid dehydrogenase/isomerase [Oryza sativa Japonica Group] gi|108708710|gb|ABF96505.1| NAD dependent epimerase/dehydratase family protein, expressed [Oryza sativa Japonica Group] Length=474 Score = 196 bits (498), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 130/370 (36%), Positives = 188/370 (51%), Gaps = 30/370 (8%) Query 17 VLVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQG------------- 62 +VTGG GF +LV LL G W VR D P++ + E + G Sbjct 14 CVVTGGRGFAARHLVAMLLRSGEWLVRVADLPPAIALDRDEEEGILGAALREGRAAYASA 73 Query 63 DITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAG 122 D+ + AAA +G D +FH AA +S+ + + ++VNV GT+N++ A R Sbjct 74 DLRNKAQVAAAFEGADVVFHMAA-----PDSSINNFHLH--YSVNVEGTKNVIDACIRCK 126 Query 123 VQRFVYTSSNSVVMGG-QNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTC 181 V+R +YTSS SVV G I DE++PY D+FND Y+ETK AE+ V+ NG DG+LTC Sbjct 127 VKRLIYTSSPSVVFDGIHGIFDADESMPYPDKFNDSYSETKADAEKLVMKANGRDGLLTC 186 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 IRPS I+G GD+ + L + G K ++G S D +YV N+ +G + A L Sbjct 187 CIRPSSIFGPGDKLLVPSLVTAARAGKSKYIIGDGSNYYDFTYVENVAYGHVCAEKTLSS 246 Query 242 -DGT--APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWV--MTGWQRLH 296 DG A G+ YFI + E I +EF +LE G P ++I + V M W Sbjct 247 EDGAKRAAGKTYFITNMEAIKFWEFMSLILEGLGYERPSIKIPVSVMMPVAHMVEWTYKT 306 Query 297 F-RFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQM 355 F R+G P L P + L + FS ++A+ LGYEP+ + + L + Y L Q Sbjct 307 FARYGMKIPQLTPSRIRLLSCNRTFSCSRAKDQLGYEPIVSLKDGLKRTIESYPHL--QA 364 Query 356 KNEARAEKTA 365 +N+ K + Sbjct 365 QNQRSISKAS 374 >gi|115453453|ref|NP_001050327.1| Os03g0405000 [Oryza sativa Japonica Group] gi|31415899|gb|AAP50920.1| putative 3-beta hydroxysteroid dehydrogenase/isomerase [Oryza sativa Japonica Group] gi|108708709|gb|ABF96504.1| NAD dependent epimerase/dehydratase family protein, expressed [Oryza sativa Japonica Group] gi|113548798|dbj|BAF12241.1| Os03g0405000 [Oryza sativa Japonica Group] gi|215678510|dbj|BAG92165.1| unnamed protein product [Oryza sativa Japonica Group] Length=561 Score = 196 bits (498), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 130/370 (36%), Positives = 188/370 (51%), Gaps = 30/370 (8%) Query 17 VLVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQG------------- 62 +VTGG GF +LV LL G W VR D P++ + E + G Sbjct 14 CVVTGGRGFAARHLVAMLLRSGEWLVRVADLPPAIALDRDEEEGILGAALREGRAAYASA 73 Query 63 DITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAG 122 D+ + AAA +G D +FH AA +S+ + + ++VNV GT+N++ A R Sbjct 74 DLRNKAQVAAAFEGADVVFHMAA-----PDSSINNFHLH--YSVNVEGTKNVIDACIRCK 126 Query 123 VQRFVYTSSNSVVMGG-QNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTC 181 V+R +YTSS SVV G I DE++PY D+FND Y+ETK AE+ V+ NG DG+LTC Sbjct 127 VKRLIYTSSPSVVFDGIHGIFDADESMPYPDKFNDSYSETKADAEKLVMKANGRDGLLTC 186 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 IRPS I+G GD+ + L + G K ++G S D +YV N+ +G + A L Sbjct 187 CIRPSSIFGPGDKLLVPSLVTAARAGKSKYIIGDGSNYYDFTYVENVAYGHVCAEKTLSS 246 Query 242 -DGT--APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWV--MTGWQRLH 296 DG A G+ YFI + E I +EF +LE G P ++I + V M W Sbjct 247 EDGAKRAAGKTYFITNMEAIKFWEFMSLILEGLGYERPSIKIPVSVMMPVAHMVEWTYKT 306 Query 297 F-RFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQM 355 F R+G P L P + L + FS ++A+ LGYEP+ + + L + Y L Q Sbjct 307 FARYGMKIPQLTPSRIRLLSCNRTFSCSRAKDQLGYEPIVSLKDGLKRTIESYPHL--QA 364 Query 356 KNEARAEKTA 365 +N+ K + Sbjct 365 QNQRSISKAS 374 >gi|226495071|ref|NP_001150065.1| sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [Zea mays] gi|195636428|gb|ACG37682.1| sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [Zea mays] Length=552 Score = 193 bits (491), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 127/370 (35%), Positives = 185/370 (50%), Gaps = 30/370 (8%) Query 17 VLVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQG------------- 62 +VTGG GF +LVT LL G W VR D P++ + E G Sbjct 11 CVVTGGRGFAARHLVTMLLRSGEWRVRVADLGPAITLDRDEEEGFLGAALREGQAVYVSA 70 Query 63 DITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAG 122 D+ D A A +G + +FH AA +S+ + + + VNV GT+N++ R Sbjct 71 DLRDKAQVARAFEGAEVVFHMAA-----PDSSINNFHLH--YGVNVDGTKNVIDTCIRCK 123 Query 123 VQRFVYTSSNSVVMGG-QNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTC 181 V+R +YTSS SVV G I DE++PY D+FND Y+ETK AE+ V+ NG +G+LTC Sbjct 124 VKRLIYTSSPSVVFDGVHGIFNADESMPYPDKFNDSYSETKADAEKLVMRANGREGLLTC 183 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 IRPS I+G GD+ M L + G K ++G + D +YV N+ +G + A L Sbjct 184 CIRPSSIFGPGDKLMVPSLVAAARAGKSKYIIGDGNNYYDFTYVENVAYGHVCAEKTLSS 243 Query 242 -DGT--APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWV--MTGWQRLH 296 DG A G+ YFI + EPI +EF +LE G P ++I + V + W Sbjct 244 EDGAKIAAGKTYFITNMEPIKFWEFMSLILEGLGYERPSVKIPVSVMMPVAHVVEWTYQK 303 Query 297 F-RFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQM 355 F ++G P L P + L + FS ++A+ LGYEPL + + + + Y L Q Sbjct 304 FAKYGMKVPQLTPSRIRLLSCNRTFSCSRAKEQLGYEPLVSLKDGVKRTVESYSHL--QA 361 Query 356 KNEARAEKTA 365 +N K + Sbjct 362 QNHRSISKAS 371 >gi|148654401|ref|YP_001274606.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Roseiflexus sp. RS-1] gi|148566511|gb|ABQ88656.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Roseiflexus sp. RS-1] Length=338 Score = 190 bits (483), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 126/336 (38%), Positives = 167/336 (50%), Gaps = 18/336 (5%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 LV GG GF+G +LV LL +G VR FDR P P++E+ QGDI AD A Sbjct 8 CLVIGGNGFIGRHLVELLLRQGRPVRVFDRTPC---DDPRVEMFQGDIRRADEVQRACAD 64 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVM 136 +F AA+++ G Q + VNV G N++ A R V+TSS V Sbjct 65 AAVVFQCAAVVDWHPGRE------QTLYEVNVIGNRNVIAACTARRNTRLVFTSSIDAVF 118 Query 137 GGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTM 196 G+ I GDETLPY R Y TK+VAE+ LA G +G++TCAIRP+G++G GD Sbjct 119 AGRPIRNGDETLPYPTRHLSFYGHTKMVAEQETLAATGRNGLMTCAIRPAGVYGPGDPYR 178 Query 197 FRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAE 256 + +G + V +G AR ++ YV N+ H ILAA L PD GQ Y + D Sbjct 179 MPTVIAEARRGSL-VRLGDGRARFNHVYVENVAHVHILAADRLTPDSPVNGQCYVVTDQP 237 Query 257 PINMFEFARPVLEACGQRWPKMRISGP-----AVRWVMTGWQRLHFRFGFPAPLLEPLAV 311 N F+F + A G P R + P A+ V+ GW L R F PLL V Sbjct 238 ARNFFDFVESFVVAMG--LPAARRTIPYRAAYALATVLEGWAHLT-RARFGKPLLTRSVV 294 Query 312 ERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPY 347 +D +F+ AKA RDLGY P + A L + Sbjct 295 ASTCVDCWFTSAKATRDLGYAPQVSETDAFERTLAW 330 >gi|281206047|gb|EFA80236.1| 3beta-hydroxysteroid dehydrogenase [Polysphondylium pallidum PN500] Length=343 Score = 189 bits (480), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 122/335 (37%), Positives = 178/335 (54%), Gaps = 20/335 (5%) Query 14 LGRVLVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQGDITDADVCAA 72 + + LV GG+GF+G +V LL R V FD S + GDI + D Sbjct 1 MKKYLVVGGSGFLGRYIVEALLARSERDVHVFDIRKSFEDERVTFHI--GDICNIDDLVE 58 Query 73 AVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSN 132 A G+DT+FHTA+ MG D Y + VNV GTENL+ A +R V++ +YTSS+ Sbjct 59 ACRGVDTVFHTASPTHGMG----YDIY----YKVNVTGTENLIEACKRTQVKQLIYTSSS 110 Query 133 SVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNG 192 SVV G +I GDETLPY D+ D Y +TK + ER VLA N +LTCAIRP+GI+G Sbjct 111 SVVFNGSDIVNGDETLPYVDKHLDPYNKTKELGERAVLAANST-LLLTCAIRPAGIFGPR 169 Query 193 DQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFI 252 D + + ++ +G K + G D +Y+ N++H +LAA + PGQAYFI Sbjct 170 DVQGWPQYLKAAKEGKNKFMFGDGKNLCDWTYIDNVVHAHLLAADKMTVHSDIPGQAYFI 229 Query 253 NDAEPINMFEFARPVLEACGQRWPKMRISGPAVR---WVMTGWQRLHFRFGFPAPLLEPL 309 + +P+ ++ EA G PK ++ + W++ L FG L + Sbjct 230 TNDDPVIFWDMPIYAYEAFGYERPKYKVPFGVIYVIAWMIDLVVALAKLFG--VTLHPTI 287 Query 310 AVERLYLDN---YFSIAKARRDLGYEPLFTTQQAL 341 + R+ N YF+I+KA+RDL Y+P+ T ++ L Sbjct 288 TLFRIVYSNSTRYFNISKAKRDLNYKPIVTYKEGL 322 >gi|62955325|ref|NP_001017674.1| sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [Danio rerio] gi|62204675|gb|AAH93332.1| NAD(P) dependent steroid dehydrogenase-like [Danio rerio] gi|182891368|gb|AAI64386.1| Nsdhl protein [Danio rerio] Length=345 Score = 188 bits (478), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 122/344 (36%), Positives = 175/344 (51%), Gaps = 21/344 (6%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFD-RAPSLLPAHPQLEVLQGDITDADVCAAAV 74 R V GG+GF+G +LV L+DRG+ V FD R LP + QGD+ D A+ Sbjct 11 RCTVIGGSGFLGRHLVERLVDRGYTVNVFDIRQAYELPG---VTFYQGDLCDKLALVMAL 67 Query 75 DGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSV 134 + +FH A+ S QR VN+ GT ++ A AGVQ+ + TSS SV Sbjct 68 KEVSIVFHCAS----PAPGSDDGALFQR---VNIDGTRTVIQACHEAGVQKLILTSSASV 120 Query 135 VMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVL-AQNGVDGMLTCAIRPSGIWGNGD 193 V G +I G E LPY + D YTETK+ E+ VL A + G LT AIRP GI+G D Sbjct 121 VFEGTDIKNGKEDLPYAKKPIDYYTETKIKQEKLVLEACSKEKGFLTVAIRPHGIFGPRD 180 Query 194 QTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIN 253 + L ++ +G +K ++G S +D +YV N++HG ILAA HL D GQAY I Sbjct 181 PQLVPILVDTARRGKMKFIIGDGSNLVDFTYVENVVHGHILAAEHLKADSPLCGQAYHIT 240 Query 254 DAEPINMFEFARPVLEACGQRWPKMRISGPAVR------WVMTGWQRLHFRFGFPAPLLE 307 + EP+ ++F +L G P+ + V W ++ R +F P Sbjct 241 NDEPVRFWDFMSQILVGLGYSAPRYHLPYALVYGIALLLWFISLILRPLIQF---KPTFS 297 Query 308 PLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSL 351 P+ V +Y+S A+A++D+GY PL Q+A+ + Y L Sbjct 298 PMRVALAGTHHYYSCARAKQDMGYRPLVPLQEAVVRTVESYPHL 341 >gi|225429728|ref|XP_002282161.1| PREDICTED: hypothetical protein [Vitis vinifera] Length=550 Score = 187 bits (474), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 124/358 (35%), Positives = 177/358 (50%), Gaps = 33/358 (9%) Query 18 LVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPS--LLPAHPQ-----------LEVLQGD 63 +VTGG GF +LV L+ G + VR D PS L P+ + E + D Sbjct 9 VVTGGRGFAARHLVEMLIRSGRFSVRIADLGPSIKLEPSEEKGLLGEALQSGRAEYVSAD 68 Query 64 ITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGV 123 + D A G + +FH AA +S+ + Q +VNV GT+N++ A V Sbjct 69 LRDKAQVLKACQGAEAVFHMAA-----PDSSINN--HQLHHSVNVQGTKNVIDACIEQKV 121 Query 124 QRFVYTSSNSVVMGG-QNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCA 182 +R +YTSS SVV G I GDE+LPY D+ ND Y+ TK E V+ NG +G+LTC Sbjct 122 KRLIYTSSPSVVFDGVHGIFNGDESLPYPDKHNDSYSATKAEGEALVIKSNGTNGLLTCC 181 Query 183 IRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPD 242 IRPS I+G GD+ + L + G K ++G + D +YV N+ H I A L + Sbjct 182 IRPSSIFGPGDKLLVPSLVNAARAGKSKFIIGDGNNMYDFTYVENVAHAHICAEQALASE 241 Query 243 GT----APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWV----MTGWQ- 293 G A GQAYFI + EPI +EF +LE G P+++I PA+ + M W Sbjct 242 GKIAEQAAGQAYFITNMEPIKFWEFVSLILEGLGYERPRIKI--PALVMMPIAHMVEWTY 299 Query 294 RLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSL 351 ++ +G P L P + L FS +KA+ L Y P+ + Q+ L + Y L Sbjct 300 KMLAPYGMKVPQLTPSRIRLLSCSRTFSCSKAKDQLSYTPIVSLQEGLRRTIDSYPDL 357 >gi|159901211|ref|YP_001547458.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Herpetosiphon aurantiacus DSM 785] gi|159894250|gb|ABX07330.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Herpetosiphon aurantiacus DSM 785] Length=340 Score = 186 bits (473), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 126/333 (38%), Positives = 165/333 (50%), Gaps = 25/333 (7%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 R LV GG GFVG +LV LL GH VR FD P PQ+E + GD+ A+ A Sbjct 8 RALVIGGCGFVGKHLVQQLLAAGHPVRVFDLQPY---PDPQVESVVGDLRKAEQVLQACH 64 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 + T+F AA ++ G + Q VNV G ++++ A Q GV + +YTSS VV Sbjct 65 DVGTVFLCAAAVDWGWGNA------QLLHDVNVLGPQHVVAACQATGVAQLIYTSSVDVV 118 Query 136 MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQT 195 G+ I GDE LPY + D+Y TK ER VLA NG G+ T A+R G++G GD Sbjct 119 FEGKPIRAGDEQLPYPKQHLDIYGATKTAGERLVLAANGQAGLATSALRLGGVYGPGDSH 178 Query 196 MFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDA 255 L +G + L G SAR + YV N HG ILAA L DG GQAYF+ D Sbjct 179 RLPSLVNLGKRGPIPRL-GNGSARFSHIYVENAAHGHILAAQRLTADGAMGGQAYFLVDP 237 Query 256 EPINMFEFARPVLEACGQRWPKMRI--------SGPAVRWVMTGWQRLHFRFGFPAPLLE 307 P N F F +P++EA G R K + + P+ W T + P L Sbjct 238 NPDNFFLFLKPIVEALGLRMAKRHVPFGLMHFLAWPSEFWYRTTRSKTR-------PSLT 290 Query 308 PLAVERLYLDNYFSIAKARRDLGYEPLFTTQQA 340 V +D +F+ AKA D GY+PL +A Sbjct 291 RYTVTSTCVDFWFTGAKAANDFGYQPLVDLAEA 323 >gi|222056234|ref|YP_002538596.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Geobacter sp. FRC-32] gi|221565523|gb|ACM21495.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Geobacter sp. FRC-32] Length=331 Score = 185 bits (470), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 115/329 (35%), Positives = 173/329 (53%), Gaps = 14/329 (4%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 + LVTGG GF+G+ +V L+ RG VRSF R+ A +E +QGD+ D D A Sbjct 2 KALVTGGGGFLGSAIVRLLMTRGDEVRSFSRSEYPELAQLGVEQVQGDLADQDCLMEAAS 61 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 G D IFH AA A + +Y A NV GTEN++ A + G++ VYT S SV+ Sbjct 62 GCDIIFHVAA------QAGIWGDYAGYHRA-NVTGTENIIAACRENGIKHLVYTGSPSVI 114 Query 136 MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQT 195 G+++ GGDE+LPY F Y +TK +AE+ VLA NG + + T ++RP IWG GD Sbjct 115 FDGRDVEGGDESLPYPVHFEANYPKTKALAEQMVLAANGPE-LATVSLRPHLIWGPGDNH 173 Query 196 MFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDA 255 + ++ G ++ +G + +D YV N +LAA L D G++YFI++ Sbjct 174 LVPRIIARAKAGKLR-RIGNRHCLVDTVYVDNAAQAHLLAADRLTHDSPIGGKSYFISNG 232 Query 256 EPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFP---APLLEPLAVE 312 +PI ++E +L+A G P R P + + ++F P P + + Sbjct 233 QPIPLWEMVNAILDAAGLP-PVTRTIPPQAAYAIGALCEQLWKF-LPMKGEPPMTRFVAK 290 Query 313 RLYLDNYFSIAKARRDLGYEPLFTTQQAL 341 L ++F I+ ARRDLGY+P + + L Sbjct 291 ELSTAHWFDISAARRDLGYQPEISIAEGL 319 >gi|297839517|ref|XP_002887640.1| hypothetical protein ARALYDRAFT_895527 [Arabidopsis lyrata subsp. lyrata] gi|297333481|gb|EFH63899.1| hypothetical protein ARALYDRAFT_895527 [Arabidopsis lyrata subsp. lyrata] Length=494 Score = 183 bits (464), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 118/354 (34%), Positives = 183/354 (52%), Gaps = 26/354 (7%) Query 17 VLVTGGAGFVGANLVTTLLDRGHW-VRSFD---RAP-SLLPAHPQLEVLQGDITDADVCA 71 V VTGG G VG+N+ LL RG VRS D +P S L ++ + GD+ + Sbjct 16 VAVTGGLGLVGSNICLELLRRGALQVRSLDCRTTSPWSDLLKESGIQCINGDVVSGEDVE 75 Query 72 AAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSS 131 A++G+D + H A+ GG+ R VNV GT N+L + G+ R VY S+ Sbjct 76 EALEGVDCVIHLAS----YGGSGKEMVRTHRIEEVNVEGTRNVLETCMKKGITRLVYLST 131 Query 132 NSVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNG--VDG-----MLTCA 182 + VV GG+ I GDETLPY +D++ Y TK +AE+ VL NG V+ + TCA Sbjct 132 HGVVFGGKEIESGDETLPYVASDQYVSSYDRTKSIAEQLVLENNGRPVENGRGSLLSTCA 191 Query 183 IRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPD 242 IR ++G ++ ++ G +G S++ D YV N++ +LA L+ + Sbjct 192 IRCPIVYGPAEEKYLDRIISDARLGLFLFKIGDASSKTDWIYVDNIVFALMLATTDLLNE 251 Query 243 -GTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRIS-------GPAVRWVMTGWQR 294 A G+AYF++D PIN FEF +P+L+ PK+ +S G + T Sbjct 252 HSKASGKAYFVSDDNPINFFEFLQPLLKNLDYDLPKLSLSVSLAVLLGTICEAIYTMLTP 311 Query 295 LHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYY 348 + + P PL+ P V ++ + +Y+SI KA+ +LGYEP ++A++E Y+ Sbjct 312 VLNQRWIPQPLILPPEVYKVGVTHYYSIRKAKEELGYEPTTQPKEAMSETFTYF 365 >gi|330801146|ref|XP_003288591.1| 3beta-hydroxysteroid dehydrogenase [Dictyostelium purpureum] gi|325081381|gb|EGC34899.1| 3beta-hydroxysteroid dehydrogenase [Dictyostelium purpureum] Length=347 Score = 183 bits (464), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 117/350 (34%), Positives = 180/350 (52%), Gaps = 15/350 (4%) Query 18 LVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 LV GG GF+G +V +LL++G V FD S + GDI + A G Sbjct 7 LVVGGCGFLGRFIVESLLNKGETNVHVFDIRKSFEDDRVTFHI--GDIRKQEDLEKACKG 64 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVM 136 I T+FHTA+ MG D Y ++VNV GT+ L+ A +GV++ VYTSS+SVV Sbjct 65 ITTVFHTASPTHGMG----YDIY----YSVNVVGTQKLVDACIASGVKQLVYTSSSSVVF 116 Query 137 GGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTM 196 G +IAGGDET+PY + D Y +TK + E+ V+ +G G+L CA+RP+GI+G + Sbjct 117 NGSDIAGGDETMPYVKKHFDPYNKTKELGEKEVIKAHG-SGLLVCALRPAGIFGPREVQG 175 Query 197 FRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAE 256 + + + +G K + G D +Y+ N++H ILAA H+ P+ G YFI + E Sbjct 176 WPQFLNAAKEGKNKFMFGSGDNLCDWTYIDNVVHAHILAAEHMTPESNVSGNIYFITNDE 235 Query 257 PINMFEFARPVLEACGQRWPKMRISGP---AVRWVMTGWQRLHFRFGFPAPLLEPLAVER 313 PI ++ EA G PK++I + WV+ L F P + + Sbjct 236 PIPFWDMPIYAYEAFGYEKPKIKIPFTLMYGIAWVIEIIVLLLSPFVKIHPTITVFRMVY 295 Query 314 LYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEK 363 YF+I KA+RDL Y+P+ ++ + +++ + Q N++ K Sbjct 296 TNATRYFNIEKAKRDLKYKPIVPLKEGMKRTKEWFLENYPQYINKSIDNK 345 >gi|328874398|gb|EGG22763.1| 3beta-hydroxysteroid dehydrogenase [Dictyostelium fasciculatum] Length=343 Score = 182 bits (463), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 128/355 (37%), Positives = 179/355 (51%), Gaps = 31/355 (8%) Query 18 LVTGGAGFVGANLVTTLLDRGHW-VRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 LV GG GF+G +V LL RG V FD S + GDI + A G Sbjct 5 LVVGGCGFLGRYIVEALLARGEKKVHIFDIRKSFEDDRVTFHI--GDIRKLEDLERACKG 62 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVM 136 IDT+FHTA+ MG D Y ++VNV GTE L+ A Q +GV + VYTSS+SVV Sbjct 63 IDTVFHTASPTHGMG----YDLY----YSVNVTGTEMLVKACQNSGVAQLVYTSSSSVVF 114 Query 137 GGQNIAGGDETLPYTDRFNDLYTETKVVAERFVL--AQNGVDGML-TCAIRPSGIWGNGD 193 G +I GDETLPY + D Y +TK + ER VL A N + L CAIRP+GI+G D Sbjct 115 NGADIVNGDETLPYVGQHLDPYNKTKELGERAVLDVATNDPNSKLAVCAIRPAGIFGPRD 174 Query 194 QTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIN 253 + + + +G K + G D +Y+ N++HG +LAA +VP GQAYFI Sbjct 175 VQGWPQFLIAAKEGKNKFMFGTGKNLCDWTYIDNVVHGHLLAADKMVPGSKINGQAYFIT 234 Query 254 DAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEP----- 308 + EPI + EA G PK +I + ++ F LL+P Sbjct 235 NDEPIPFWNMPIYAYEAFGYEKPKFKIPFAVMYYIA-------LLIDFFVALLKPIKTIH 287 Query 309 --LAVERLYLDN---YFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNE 358 + + R+ N YF+I KA+RDLGY+P+ + Q+ + ++ + Q N+ Sbjct 288 PTITLFRMVYTNATRYFNINKAKRDLGYKPIVSVQEGMDRTRDWFKINYSQFINK 342 >gi|149178706|ref|ZP_01857290.1| hypothetical protein PM8797T_01754 [Planctomyces maris DSM 8797] gi|148842481|gb|EDL56860.1| hypothetical protein PM8797T_01754 [Planctomyces maris DSM 8797] Length=333 Score = 182 bits (463), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 116/331 (36%), Positives = 173/331 (53%), Gaps = 9/331 (2%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 VLVTGG GF+G +V L+ G VR R +E +QGDI DA A +G Sbjct 3 VLVTGGGGFLGLYIVEQLVAAGETVRVLCRGEYQRLKELGVETVQGDIRDATTVERACEG 62 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVM 136 I+T++HTAA+ + G + +++N GT N++ + Q GV R VYTSS SVV Sbjct 63 IETVYHTAAVSGIWG-------HWDYFYSINTRGTLNVIASCQSQGVTRLVYTSSPSVVY 115 Query 137 GGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTM 196 G E+LPY++ F Y TK++AER VL NG +G+ T A+RP IWG D + Sbjct 116 DGSAHENATESLPYSEHFLCHYPHTKMLAERAVLQANGENGLATVALRPHLIWGPRDNHL 175 Query 197 FRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAE 256 +L + G ++ VG + + SYV N + AAA L PD GQAYFIN+ E Sbjct 176 IPRLIQRARSGRLR-QVGEGTNLISMSYVENAAAAHLQAAARLFPDSPVGGQAYFINEPE 234 Query 257 PINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPA-PLLEPLAVERLY 315 P+ M+E+ +L G + K +IS A + + + + + P P + +L Sbjct 235 PVLMWEWINQLLVEAGLQPVKKQISTKAAKRIGSVLEFVFRVLHLPGEPPMTRFLASQLS 294 Query 316 LDNYFSIAKARRDLGYEPLFTTQQALTECLP 346 +Y+ +++AR D GYEP + ++A+ P Sbjct 295 SSHYYDVSRARHDFGYEPCVSFEEAMRRMKP 325 >gi|50753891|ref|XP_414167.1| PREDICTED: hypothetical protein [Gallus gallus] Length=391 Score = 182 bits (463), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 121/348 (35%), Positives = 185/348 (54%), Gaps = 22/348 (6%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 VL+TGG G+ G L T+ +G V FD L P ++ +QG++ A+ Sbjct 11 VLITGGGGYFGFRLGCTIYKKGVDVILFDVTKPLQPVPEGIKFMQGNVCCLAEVEEALKD 70 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFA-VNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 + +FH A+ G S ++ ++ VNV GTEN++ A + GV VYTS+ +V+ Sbjct 71 VICVFHIASY-----GMSGREQLNRKLIEDVNVKGTENVIQACKSTGVSSLVYTSTYNVI 125 Query 136 MGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGVD-----GML-TCAIRPSG 187 GGQ I GDE+LPY D Y+ TK +AE VL NG + G+L TCA+RP+G Sbjct 126 FGGQIIENGDESLPYLPLHLHPDHYSRTKSLAEMKVLKANGTELGNGKGVLRTCALRPAG 185 Query 188 IWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDG--TA 245 I+G G+Q ++ + +G K + G + ++ +V NL+ ILA L + A Sbjct 186 IYGPGEQRHLPRIVSYIERGLFKFVYGDPLSLVEFVHVDNLVQAHILAFEALKANKKHIA 245 Query 246 PGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFP--- 302 GQAYFI+D P+N FEF RP++E G ++P R+ V + + +HF G Sbjct 246 AGQAYFISDGRPVNNFEFFRPLVEGLGYKFPTCRLPLSLVYFFAFLTEVVHFLVGHVYNF 305 Query 303 APLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVS 350 PLL V + + +YFS+ KAR++LGYEP + +L E + ++ S Sbjct 306 QPLLTRTEVYKTGVTHYFSMEKARKELGYEP---QKYSLNEVVEWFRS 350 >gi|62859757|ref|NP_001017290.1| NAD(P) dependent steroid dehydrogenase-like [Xenopus (Silurana) tropicalis] Length=345 Score = 182 bits (462), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 113/340 (34%), Positives = 174/340 (52%), Gaps = 13/340 (3%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 + V GG+GF+G ++V LL++G+ V FD + +++ GD+ A+ Sbjct 11 KCTVIGGSGFLGQHIVERLLEKGYTVNVFDIRQGF--ENERVQFFIGDLCSKKDLLPALQ 68 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 G++ +FH A+ A +D ++ + VN GT ++ + GVQ+ V TSS SV+ Sbjct 69 GVNVVFHCAS------PAPFSDN-KELFYRVNFTGTRTIIEVCKEVGVQKLVLTSSASVI 121 Query 136 MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDG-MLTCAIRPSGIWGNGDQ 194 G++I G ETLPY + D YTETK++ E+ VLA N + LT AIRP GI+G D Sbjct 122 FEGKDIKNGSETLPYASQPIDYYTETKILQEKEVLAANDPENNFLTVAIRPHGIFGPRDP 181 Query 195 TMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIND 254 + L E+ G +K ++G +D +YV N++HG ILAA HL D G+AY I + Sbjct 182 QLVPILIETAKSGKMKFMIGNGKNLVDFTYVENVVHGIILAAEHLHKDAPLCGKAYHITN 241 Query 255 AEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHF---RFGFPAPLLEPLAV 311 +PI + F +L PK RI ++ L F F P P+ V Sbjct 242 DQPIPFWTFLSRILVGLNYEAPKYRIPYWLAYYLAMFVSLLVFIISPFIKIKPTFTPMRV 301 Query 312 ERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSL 351 +Y+S +A++D+GY+P+ T QAL + Y L Sbjct 302 ALAGTYHYYSCERAKKDMGYKPVVTLDQALERTIQSYSHL 341 >gi|148229598|ref|NP_001090495.1| short-chain dehydrogenase/reductase family 42E member 1 [Xenopus laevis] gi|123911482|sp|Q0IH73.1|D42E1_XENLA RecName: Full=Short-chain dehydrogenase/reductase family 42E member 1 gi|114107900|gb|AAI23280.1| MGC154557 protein [Xenopus laevis] Length=386 Score = 181 bits (460), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 130/345 (38%), Positives = 183/345 (54%), Gaps = 28/345 (8%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFD-RAPSL-LPAHPQLEVLQGDITDADVCAAAV 74 V++TGG G+ G L TL ++G V FD R P LP + +QGD+ V Sbjct 11 VVITGGGGYFGHRLGCTLHEKGVHVILFDIRKPDQELPE--GIHFVQGDVRSLSQLEDVV 68 Query 75 DGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSV 134 G +FHTA+ G + +RQ+ A+NV GTEN++ A V R VYTS+ +V Sbjct 69 AGASCVFHTAS----YGMSGKEQLHRQKIEAINVRGTENIIQACINTNVPRLVYTSTFNV 124 Query 135 VMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGVD-----GML-TCAIRPS 186 + GGQ I GDE+LPY D F D Y+ TK VAE FVL N + G L TC++R + Sbjct 125 IFGGQTIRDGDESLPYLPQDAFVDNYSRTKTVAEMFVLKMNNQELKNNSGFLRTCSLRAA 184 Query 187 GIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT-- 244 GI+G G+Q ++ ++ KG + G + + +V NLI ILAA L + Sbjct 185 GIYGPGEQRHLPRIISALEKGMFLFVYG-DNPLVQFVHVDNLISAHILAAEALTSEKKYI 243 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRW--VMTGWQRLHFRFGFP 302 A GQ YFI+D P+N FEF RP++E G ++P +R V + +T W +HF F P Sbjct 244 AAGQPYFISDGPPVNNFEFFRPLVEGLGYKFPSLRFPLSLVYFFAFLTEW--IHF-FISP 300 Query 303 A----PLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTE 343 P+L V + + +YF I KA R+LG+EP T Q + E Sbjct 301 VCDFQPILTRAEVFKTGVTHYFKIEKATRELGFEPQPFTMQDVAE 345 >gi|326927427|ref|XP_003209894.1| PREDICTED: short-chain dehydrogenase/reductase family 42E member 1-like [Meleagris gallopavo] Length=391 Score = 181 bits (459), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 121/348 (35%), Positives = 184/348 (53%), Gaps = 22/348 (6%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDG 76 VL+TGG G+ G L T+ G V FD L P ++ +QG++ A+ Sbjct 11 VLITGGGGYFGFRLGCTIYKMGVDVILFDVMKPLQPVPEGIKFMQGNVCCLAEVEEALKD 70 Query 77 IDTIFHTAAIIELMGGASVTDEYRQRSFA-VNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 + +FH A+ G S ++ ++ VNV GTEN++ A + GV VYTS+ +V+ Sbjct 71 VICVFHIASY-----GMSGREQLNRKLIEDVNVKGTENVIQACKSTGVSSLVYTSTYNVI 125 Query 136 MGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGV-----DGML-TCAIRPSG 187 GGQ I GDE+LPY D Y+ TK +AE VL NG +G+L TCA+RP+G Sbjct 126 FGGQIIENGDESLPYLPLHLHPDHYSRTKSLAEMKVLKANGTELGNGEGVLRTCALRPAG 185 Query 188 IWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDG--TA 245 I+G G+Q ++ + +G K + G + ++ +V NL+ ILA L + A Sbjct 186 IYGPGEQRHLPRIVSYIERGLFKFVYGDPLSLVEFVHVDNLVQAHILAFEALKANKKHIA 245 Query 246 PGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFP--- 302 GQAYFI+D P+N FEF RP++E G ++P R+ V + + +HF G Sbjct 246 AGQAYFISDGRPVNNFEFFRPLVEGLGYKFPTCRLPLSLVYFFAFLTEVVHFLIGHIYNF 305 Query 303 APLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVS 350 PLL V + + +YFS+ KAR++LGYEP + +L E + ++ S Sbjct 306 QPLLTRTEVYKTGVTHYFSMEKARKELGYEP---QKYSLNEVVEWFRS 350 >gi|301764697|ref|XP_002917765.1| PREDICTED: short-chain dehydrogenase/reductase family 42E member 1-like [Ailuropoda melanoleuca] Length=393 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 121/334 (37%), Positives = 179/334 (54%), Gaps = 25/334 (7%) Query 17 VLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAH--PQ-LEVLQGDITDADVCAAA 73 VL+TGG G+ G L L RG +V FD + PAH P+ ++ + GDI A Sbjct 11 VLITGGGGYFGFRLGCALNQRGFYVILFDISS---PAHAIPEGIKFIHGDIRHLSDVEKA 67 Query 74 VDGIDT--IFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSS 131 +D ++H A+ G + R VNVGGT+N+L +R GV RFVYTS+ Sbjct 68 FQDVDVMCVYHIAS----YGMSGREQLNRSLIEEVNVGGTDNILQVCRRRGVPRFVYTST 123 Query 132 NSVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGV-----DGML-TCAI 183 +V+ GGQ I GDE+LPY D Y+ TK +AE+ VL +G DG+L TCA+ Sbjct 124 FNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEADGTSLVRRDGVLRTCAL 183 Query 184 RPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDG 243 RP+GI+G G+Q ++ + +G K + G + ++ +V NL+ ILA+ L D Sbjct 184 RPAGIYGPGEQRHLPRIVSYIERGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALKADK 243 Query 244 --TAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHF---R 298 A GQ YF++D P+N FEF RP++E G +P +R+ + + +HF R Sbjct 244 GHVASGQPYFVSDGRPVNNFEFFRPLVEGLGYTFPSIRLPLTLIYCFAFLTEMVHFILGR 303 Query 299 FGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYE 332 F P L V + + +YFS+ KA+++LGYE Sbjct 304 FYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYE 337 >gi|255539320|ref|XP_002510725.1| hydroxysteroid dehydrogenase, putative [Ricinus communis] gi|223551426|gb|EEF52912.1| hydroxysteroid dehydrogenase, putative [Ricinus communis] Length=478 Score = 180 bits (457), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 121/362 (34%), Positives = 185/362 (52%), Gaps = 40/362 (11%) Query 19 VTGGAGFVGANLVTTLLDRG-HWVRSFDRAPSLLPAHPQ----LEVLQGDITDADVCAAA 73 VTGG GFVG+ L L+ RG VR+FD P+ +H + ++GD+T A Sbjct 16 VTGGLGFVGSALCLELMRRGARQVRAFDVRPTSPWSHQLTSRGVHCIRGDLTRKSDVEKA 75 Query 74 VDGIDTIFHTAAIIELMGGASVTDEYR-QRSFAVNVGGTENLLHAGQRAGVQRFVYTSSN 132 + G+D +FH A+ G S + R R VN+ GT ++L A G++R VY S+ Sbjct 76 LRGVDCVFHLASF-----GMSGKEMIRFGRVDEVNINGTCHVLEACIEFGIKRLVYVSTY 130 Query 133 SVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGV-------DGMLTCAI 183 +VV GG+ I G+E+LPY TD D Y +K +AE+ VL NG + TCAI Sbjct 131 NVVFGGKQIVNGNESLPYFPTDDHVDSYGGSKSIAEQLVLKYNGRPLKKNNGKRLYTCAI 190 Query 184 RPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPD- 242 RP+ I+G G++ ++ G + +G + + D YV NL+ ILA+ L+ D Sbjct 191 RPAAIYGPGEERHMPRIVSYAKLGLMPFRIGDANVKTDWVYVDNLVLALILASMGLLDDI 250 Query 243 ------GTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGP----------AVR 286 A GQ YFI+D PIN FEF +P+L++ PK +S P A+ Sbjct 251 PNSGGHPVAAGQPYFISDGSPINSFEFLQPLLKSLNYDMPKASLSVPHALILGKIFGAIY 310 Query 287 WVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLP 346 ++ W R+ P P + P V ++ + +YFS KA+ +LGY P+ T ++ + + Sbjct 311 TLLYPWLN---RWWLPQPFILPAEVYKVGVTHYFSFLKAKEELGYVPMVTPREGMAATIA 367 Query 347 YY 348 Y+ Sbjct 368 YW 369 >gi|224063753|ref|XP_002196863.1| PREDICTED: short chain dehydrogenase/reductase family 42E, member 1 [Taeniopygia guttata] Length=391 Score = 180 bits (457), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 122/349 (35%), Positives = 185/349 (54%), Gaps = 22/349 (6%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 RVL+TGG G+ G L + +G V FD L ++ +QG+I A+ Sbjct 10 RVLITGGGGYFGFRLGCAIYQKGVDVILFDVVKPLQTVPEGIKFMQGNICCLSEVEEALR 69 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFA-VNVGGTENLLHAGQRAGVQRFVYTSSNSV 134 + +FH A+ G S ++ ++ VNV GTEN++ A + GV VYTS+ +V Sbjct 70 DVICVFHIASY-----GMSGREQLNRKLIEDVNVKGTENVIQACKSRGVSSLVYTSTYNV 124 Query 135 VMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGVD-----GML-TCAIRPS 186 + GGQ I GDE+LPY D Y+ TK +AE VL NG + G+L TCA+RP+ Sbjct 125 IFGGQIIENGDESLPYLPLHLHPDHYSRTKSLAEMKVLEANGAELGNGRGVLRTCALRPA 184 Query 187 GIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILA--AAHLVPDGT 244 GI+G G+Q ++ + +G K + G + ++ +V NL+ +LA A Sbjct 185 GIYGPGEQRHLPRIVSYIERGLFKFVYGDPLSLVEFVHVDNLVQAHVLASEAFRASKQHI 244 Query 245 APGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFP-- 302 A GQAYFI+D +P+N FEF RP++E G ++P R+ V + + +HF G Sbjct 245 AAGQAYFISDGKPVNNFEFFRPLVEGLGYKFPTWRLPLSLVYFFAFLTEIVHFLVGRVYN 304 Query 303 -APLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVS 350 PLL V + + +YFS+AKAR++LGYEP Q +L E + ++ S Sbjct 305 FQPLLTRTEVYKTGVTHYFSMAKARKELGYEP---QQYSLDEVVEWFRS 350 >gi|260824135|ref|XP_002607023.1| hypothetical protein BRAFLDRAFT_226900 [Branchiostoma floridae] gi|229292369|gb|EEN63033.1| hypothetical protein BRAFLDRAFT_226900 [Branchiostoma floridae] Length=384 Score = 179 bits (455), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 122/330 (37%), Positives = 183/330 (56%), Gaps = 16/330 (4%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 RVLVTGG G++G L L G + FD + A ++ ++GDIT+ + A Sbjct 5 RVLVTGGGGYLGLRLANMLRRDGANITLFDLREPIEKAAADIKFIKGDITNYEDVEDACR 64 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 G+D ++H A+ G + R+ AVNVGGT+N++ A R V R VYTS+ +VV Sbjct 65 GMDCVYHIAS----YGMSGREQLNRKLIEAVNVGGTKNVIKACCRQSVHRLVYTSTFNVV 120 Query 136 MGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNG--VDG---MLTCAIRPSGI 188 GGQ I GDE+LPY + D Y+ TK +AE +L NG V+G + TCA+RP+GI Sbjct 121 FGGQKIEFGDESLPYLPLHKHPDYYSMTKSIAEMEILKANGTVVEGGGTLRTCALRPAGI 180 Query 189 WGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDG--TAP 246 +G G+Q ++ + +G V+ G + ++ +V NL +LA L D A Sbjct 181 YGPGEQRHLPRIVSYIEQGLFAVVYGEPDSLVEFVHVDNLAKAHLLAGRALQDDKQHVAA 240 Query 247 GQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHF---RFGFPA 303 GQAYFI+D +P+N FEF RP++E G +P +R+ V + + +H+ RF Sbjct 241 GQAYFISDGKPVNNFEFFRPLVEGLGYTYPTVRVPVSVVYFFAFLTEIVHYVVGRFYNFQ 300 Query 304 PLLEPLAVERLYLDNYFSIAKARRDLGYEP 333 PLL V + + +YF++ KA+R+LGYEP Sbjct 301 PLLTRTEVYKTGVTHYFNLRKAKRELGYEP 330 >gi|225457644|ref|XP_002275214.1| PREDICTED: hypothetical protein [Vitis vinifera] Length=478 Score = 179 bits (454), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 124/364 (35%), Positives = 185/364 (51%), Gaps = 42/364 (11%) Query 18 LVTGGAGFVGANLVTTLLDRG-HWVRSFD-RAPSLLPAHPQLE-----VLQGDITDADVC 70 +VTGG GFVGA L L+ RG +R+ D R+ S P LE +QGDIT Sbjct 15 VVTGGLGFVGAALCLELVRRGARQIRAIDLRSTS--PWSDDLENKGVHCIQGDITVKKDV 72 Query 71 AAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTS 130 A+ G D +FH A+ M G + R VN+ GT ++L A G++R VYTS Sbjct 73 ERALRGADCVFHLASY--GMSGKEMIQYGRVDE--VNINGTCHILDACIEFGIKRLVYTS 128 Query 131 SNSVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGV-------DGMLTC 181 + +VV GG+ I G+E LPY D D Y+ +K +AE+ VL NG + TC Sbjct 129 TYNVVFGGKEILNGNEALPYFPLDDHVDSYSRSKSIAEQLVLKNNGRPFKNKSGKCLYTC 188 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 A+RP+ I+G G+ F ++ G + +G + + D YV NL+H ILA+ L+ Sbjct 189 AVRPAAIYGPGEDRHFPRIISLAKLGVLPFTIGEANVKGDWIYVDNLVHAQILASMGLLD 248 Query 242 D-------GTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGP----------A 284 D A GQ+YFIND P+N++EF RP+L + PK + P Sbjct 249 DIPGREKRPIAAGQSYFINDGSPVNIYEFLRPLLRSLEYDLPKASLPVPYALFMSRINCM 308 Query 285 VRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTEC 344 + ++ W R+ P PL+ P V ++ + +YFS KA+ +LGY PL + ++ + Sbjct 309 IYTLLYPWLN---RWWLPQPLMLPAEVYKVGVTHYFSYLKAKEELGYVPLVSPREGMAAT 365 Query 345 LPYY 348 + Y+ Sbjct 366 ISYW 369 >gi|297745599|emb|CBI40764.3| unnamed protein product [Vitis vinifera] Length=479 Score = 179 bits (454), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 124/364 (35%), Positives = 185/364 (51%), Gaps = 42/364 (11%) Query 18 LVTGGAGFVGANLVTTLLDRG-HWVRSFD-RAPSLLPAHPQLE-----VLQGDITDADVC 70 +VTGG GFVGA L L+ RG +R+ D R+ S P LE +QGDIT Sbjct 15 VVTGGLGFVGAALCLELVRRGARQIRAIDLRSTS--PWSDDLENKGVHCIQGDITVKKDV 72 Query 71 AAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTS 130 A+ G D +FH A+ M G + R VN+ GT ++L A G++R VYTS Sbjct 73 ERALRGADCVFHLASY--GMSGKEMIQYGRVDE--VNINGTCHILDACIEFGIKRLVYTS 128 Query 131 SNSVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLAQNGV-------DGMLTC 181 + +VV GG+ I G+E LPY D D Y+ +K +AE+ VL NG + TC Sbjct 129 TYNVVFGGKEILNGNEALPYFPLDDHVDSYSRSKSIAEQLVLKNNGRPFKNKSGKCLYTC 188 Query 182 AIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVP 241 A+RP+ I+G G+ F ++ G + +G + + D YV NL+H ILA+ L+ Sbjct 189 AVRPAAIYGPGEDRHFPRIISLAKLGVLPFTIGEANVKGDWIYVDNLVHAQILASMGLLD 248 Query 242 D-------GTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGP----------A 284 D A GQ+YFIND P+N++EF RP+L + PK + P Sbjct 249 DIPGREKRPIAAGQSYFINDGSPVNIYEFLRPLLRSLEYDLPKASLPVPYALFMSRINCM 308 Query 285 VRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTEC 344 + ++ W R+ P PL+ P V ++ + +YFS KA+ +LGY PL + ++ + Sbjct 309 IYTLLYPWLN---RWWLPQPLMLPAEVYKVGVTHYFSYLKAKEELGYVPLVSPREGMAAT 365 Query 345 LPYY 348 + Y+ Sbjct 366 ISYW 369 >gi|147900632|ref|NP_001088890.1| NAD(P) dependent steroid dehydrogenase-like [Xenopus laevis] gi|56788986|gb|AAH88699.1| LOC496236 protein [Xenopus laevis] Length=345 Score = 179 bits (453), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 112/341 (33%), Positives = 171/341 (51%), Gaps = 15/341 (4%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 + V GG+GF+G ++V LL++G+ V FD + +++ GD+ A+ Sbjct 11 KCTVIGGSGFLGQHIVERLLEKGYTVNVFDIRQGF--ENERVQFFIGDLCSKKDLIPALQ 68 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 G++ +FH A+ + + ++ + VN GT ++ A + GVQ+ V TSS SV+ Sbjct 69 GVNVVFHCAS-------PAPHSDNKELFYRVNFIGTRTIIEACKEVGVQKLVLTSSASVI 121 Query 136 MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDG-MLTCAIRPSGIWGNGDQ 194 G++I G E LPY D YTETK++ E+ VLA N + LT AIRP GI+G D Sbjct 122 FEGKDIKNGSENLPYASHPIDYYTETKILQEKEVLAANDPENNFLTVAIRPHGIFGPRDP 181 Query 195 TMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIND 254 + L E+ G +K ++G +D +YV N++HG ILA HL D G+AY I + Sbjct 182 QLVPILIETAKSGKMKFMIGNGKNLVDFTYVENVVHGIILAGEHLHKDAPLCGKAYHITN 241 Query 255 AEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFP----APLLEPLA 310 EPI + F VL PK RI ++ L F P P P+ Sbjct 242 DEPIPFWTFLSRVLVGLNYEAPKYRIPYWLAYYLAMFVSLLVFIIS-PLIKIKPTFTPMR 300 Query 311 VERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSL 351 V +Y+S +A++D+GY+P+ T QAL + Y L Sbjct 301 VALAGTYHYYSCERAKKDMGYKPVVTLDQALERTIQSYSHL 341 >gi|149918028|ref|ZP_01906521.1| NAD(P)H steroid dehydrogenase [Plesiocystis pacifica SIR-1] gi|149821033|gb|EDM80439.1| NAD(P)H steroid dehydrogenase [Plesiocystis pacifica SIR-1] Length=341 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 123/335 (37%), Positives = 179/335 (54%), Gaps = 20/335 (5%) Query 14 LGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAA 73 + R L+TG GFVG ++ LLDRG VR F R +E+++GD+ D AA Sbjct 8 MKRALITGAGGFVGKSIARALLDRGVEVRGFCRGDYPFLREWGVELVRGDVQDRAALEAA 67 Query 74 VDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNS 133 V G D +FH AA++++ G +R FA NV GT N+L A + AG ++ VYTS+ S Sbjct 68 VAGCDAVFHAAALVDIWGP-------YERFFATNVEGTRNVLAACRAAGARKLVYTSTPS 120 Query 134 VVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGD 193 VV GG+ + G DE+ PY D F Y TK +AER VLA NG + ++T AIRP +WG GD Sbjct 121 VVHGGETVDGVDESAPYPDHFEAHYPATKAIAEREVLAANGAE-LVTAAIRPHLVWGPGD 179 Query 194 QTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGT--AP-GQAY 250 ++ ++ G VK L+G +D Y+ N + I AA L P+ AP G+AY Sbjct 180 TSLMPRMIAKARTGRVK-LIGEPQP-IDTVYIDNAVAAHIAAAERLDPEHPERAPAGKAY 237 Query 251 FINDAEPINMFEFARPVLEACGQRWPKMRIS---GPAVRWVMTG-WQRLHFRFGFPAPLL 306 FI EP+ +F +L+ G + IS A V+ G W+ L R P + Sbjct 238 FITQGEPMPGPQFLNDLLDINGLPPIEATISAAKARAAAAVIEGLWKLLRIRR---EPPI 294 Query 307 EPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQAL 341 V ++ +++ I+ ARR+LGYEP + + + Sbjct 295 TRFVVSQMSTAHWYDISAARRELGYEPAVSYAEGM 329 >gi|322419646|ref|YP_004198869.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Geobacter sp. M18] gi|320126033|gb|ADW13593.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Geobacter sp. M18] Length=330 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 120/340 (36%), Positives = 173/340 (51%), Gaps = 36/340 (10%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVD 75 R LVTGG GF+G+ +V L RG V SF R A +E +GDI+D + A Sbjct 2 RALVTGGGGFLGSAMVRQLRARGDDVVSFSRGDYPELAALGVEQRRGDISDQNAVVEAAS 61 Query 76 GIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVV 135 G D +FH AA + G ++R+ A NV GTEN++ A + G++R VYT S SVV Sbjct 62 GCDIVFHVAAKAGIWG------DFREYYLA-NVAGTENVIAACRILGIRRLVYTGSPSVV 114 Query 136 MGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQT 195 G ++ G DE+LPY F Y +TK +AE+ VLA N + T ++RP IWG GD Sbjct 115 FDGSDVEGADESLPYPAHFEAPYPQTKALAEQAVLAANSPT-LATVSLRPHLIWGPGDNH 173 Query 196 MFRKLFESVLKGHVKVL--VGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFIN 253 + ++ V KG L +G++ +D +V N + AA HL PD G+AYFI+ Sbjct 174 LVPRI---VAKGRAGALRRIGKRPCLVDTVFVENAAEAHLNAADHLSPDAPPAGKAYFIS 230 Query 254 DAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTG------------WQRLHFRFGF 301 + EPI +++ +L+A G P R + G W+ L R Sbjct 231 NGEPIPLWDIVNGILDAAG--------VAPVTRSIPAGVAYAAGIACELLWKSL--RLSG 280 Query 302 PAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQAL 341 P+ +A E L ++F I+ ARRDLGY P + ++ L Sbjct 281 EPPMTRFVAKE-LATSHWFDISAARRDLGYTPRVSIEEGL 319 >gi|197118481|ref|YP_002138908.1| 3-beta-hydroxysteroid dehydrogenase/isomerase family protein [Geobacter bemidjiensis Bem] gi|197087841|gb|ACH39112.1| 3-beta-hydroxysteroid dehydrogenase/isomerase family protein [Geobacter bemidjiensis Bem] Length=330 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 119/336 (36%), Positives = 173/336 (52%), Gaps = 28/336 (8%) Query 16 RVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVL-----QGDITDADVC 70 + LVTGG GF+G+ +V LL RG SF R +P+L +L +GD++D + Sbjct 2 KALVTGGGGFLGSAIVRQLLARGDQAVSFSRG-----EYPELALLGVEQRRGDLSDPEAV 56 Query 71 AAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTS 130 A A G D +FH AA + G +EY + NV GTEN++ A +R G++R VYTS Sbjct 57 ADAARGCDVVFHVAAKAGIWG---EFEEY----YRANVTGTENVIEACRRLGIERLVYTS 109 Query 131 SNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWG 190 S SVV G ++ GGDE+LPY F Y TK +AE+ VLA N + + T ++RP IWG Sbjct 110 SPSVVFDGSDVEGGDESLPYPAHFEAHYPHTKALAEQAVLAANAPE-LATVSLRPHLIWG 168 Query 191 NGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAY 250 GD + ++ G +K +G + +D YV N + AA L G+AY Sbjct 169 PGDNHLVPRIVAKARSGALK-RIGNRPCLVDTVYVENAAEAHLNAADRLKAGSAPAGKAY 227 Query 251 FINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRW-----VMTGWQRLHFRFGFPAPL 305 FI++ EPI ++E +L A G P R P + + T W+ L R P+ Sbjct 228 FISNGEPIPLWEMVNRILAAAGLP-PITRQVSPGLAYGAGVVCETLWKML--RLSGEPPM 284 Query 306 LEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQAL 341 +A E L ++F ++ AR DLGY P + + L Sbjct 285 TRFVAKE-LATAHWFDLSAARADLGYHPRISIDEGL 319 >gi|15226138|ref|NP_180921.1| Rossmann-fold NAD(P)-binding domain-containing protein [Arabidopsis thaliana] gi|16226673|gb|AAL16229.1|AF428460_1 At2g33630/F4P9.40 [Arabidopsis thaliana] gi|2459443|gb|AAB80678.1| putative steroid dehydrogenase [Arabidopsis thaliana] gi|20260208|gb|AAM13002.1| putative steroid dehydrogenase [Arabidopsis thaliana] gi|330253770|gb|AEC08864.1| Rossmann-fold NAD(P)-binding domain-containing protein [Arabidopsis thaliana] Length=480 Score = 177 bits (448), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 125/360 (35%), Positives = 183/360 (51%), Gaps = 35/360 (9%) Query 18 LVTGGAGFVGANLVTTLLDRG-HWVRSFDRAPSLLPAHPQLE-----VLQGDITDADVCA 71 +VTGG GFVGA L L+ RG VRSFD S P L+ +QGD+T Sbjct 15 VVTGGLGFVGAALCLELVRRGARQVRSFDLRHSS-PWSDDLKNSGVRCIQGDVTKKQDVD 73 Query 72 AAVDGIDTIFHTAAIIELMGGASVTDEYR-QRSFAVNVGGTENLLHAGQRAGVQRFVYTS 130 A+DG D + H A+ G S + R R VN+ GT N+L A + + R VY S Sbjct 74 NALDGADCVLHLASY-----GMSGKEMLRFGRCDEVNINGTCNVLEAAFKHEITRIVYVS 128 Query 131 SNSVVMGGQNIAGGDETLPY--TDRFNDLYTETKVVAERFVLA------QNGVDGMLTCA 182 + +VV GG+ I G+E LPY D D Y+ TK +AE+ VL +NG M TCA Sbjct 129 TYNVVFGGKEILNGNEGLPYFPLDDHVDAYSRTKSIAEQLVLKSNGRPFKNGGKRMYTCA 188 Query 183 IRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPD 242 IRP+ I+G G+ ++ G +G S + D YV NL+ ILA+ L+ D Sbjct 189 IRPAAIYGPGEDRHLPRIVTLTKLGLALFKIGEPSVKSDWIYVENLVLAIILASMGLLDD 248 Query 243 -------GTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGP---AVRWVMTGW 292 A GQ YF++D P+N FEF RP+L++ PK IS P ++ + G+ Sbjct 249 IPGREGQPVAAGQPYFVSDGYPVNTFEFLRPLLKSLDYDLPKCTISVPFALSLGKIFQGF 308 Query 293 QRLHF----RFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYY 348 + + + P PL+ P V ++ + +YFS KA+ +LGY P ++++ + + Y+ Sbjct 309 YTVLYPWLSKSWLPQPLVLPAEVYKVGVTHYFSYLKAKEELGYVPFKSSKEGMAATISYW 368 Lambda K H 0.322 0.138 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 703601480950 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40