BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1110
Length=335
Score E
Sequences producing significant alignments: (Bits) Value
gi|308231738|ref|ZP_07413603.2| lytB-related protein lytB2 [Myco... 674 0.0
gi|31792303|ref|NP_854796.1| 4-hydroxy-3-methylbut-2-enyl diphos... 672 0.0
gi|15840547|ref|NP_335584.1| 4-hydroxy-3-methylbut-2-enyl diphos... 660 0.0
gi|240171091|ref|ZP_04749750.1| 4-hydroxy-3-methylbut-2-enyl dip... 616 2e-174
gi|183984326|ref|YP_001852617.1| 4-hydroxy-3-methylbut-2-enyl di... 602 3e-170
gi|118616061|ref|YP_904393.1| 4-hydroxy-3-methylbut-2-enyl dipho... 601 5e-170
gi|254774114|ref|ZP_05215630.1| 4-hydroxy-3-methylbut-2-enyl dip... 587 7e-166
gi|41408782|ref|NP_961618.1| 4-hydroxy-3-methylbut-2-enyl diphos... 584 6e-165
gi|254819702|ref|ZP_05224703.1| 4-hydroxy-3-methylbut-2-enyl dip... 581 5e-164
gi|296169976|ref|ZP_06851583.1| 4-hydroxy-3-methylbut-2-enyl dip... 572 3e-161
gi|145222667|ref|YP_001133345.1| 4-hydroxy-3-methylbut-2-enyl di... 571 6e-161
gi|120405583|ref|YP_955412.1| 4-hydroxy-3-methylbut-2-enyl dipho... 568 3e-160
gi|126436907|ref|YP_001072598.1| 4-hydroxy-3-methylbut-2-enyl di... 568 3e-160
gi|315443130|ref|YP_004076009.1| 4-hydroxy-3-methylbut-2-enyl di... 568 5e-160
gi|108801069|ref|YP_641266.1| 4-hydroxy-3-methylbut-2-enyl dipho... 567 8e-160
gi|118473320|ref|YP_889470.1| 4-hydroxy-3-methylbut-2-enyl dipho... 563 1e-158
gi|169628350|ref|YP_001701999.1| 4-hydroxy-3-methylbut-2-enyl di... 561 4e-158
gi|15828043|ref|NP_302306.1| 4-hydroxy-3-methylbut-2-enyl diphos... 561 7e-158
gi|8928200|sp|Q9X781.2|ISPH_MYCLE RecName: Full=4-hydroxy-3-meth... 560 9e-158
gi|342861699|ref|ZP_08718345.1| 4-hydroxy-3-methylbut-2-enyl dip... 554 9e-156
gi|289761249|ref|ZP_06520627.1| 4-hydroxy-3-methylbut-2-enyl dip... 542 3e-152
gi|118464410|ref|YP_880476.1| 4-hydroxy-3-methylbut-2-enyl dipho... 529 2e-148
gi|312138756|ref|YP_004006092.1| 4-hydroxy-3-methylbut-2-enyl di... 523 2e-146
gi|226365341|ref|YP_002783124.1| 4-hydroxy-3-methylbut-2-enyl di... 522 3e-146
gi|226307721|ref|YP_002767681.1| 4-hydroxy-3-methylbut-2-enyl di... 522 4e-146
gi|111022833|ref|YP_705805.1| 4-hydroxy-3-methylbut-2-enyl dipho... 521 4e-146
gi|54026769|ref|YP_121011.1| 4-hydroxy-3-methylbut-2-enyl diphos... 521 6e-146
gi|333921058|ref|YP_004494639.1| 4-hydroxy-3-methylbut-2-enyl di... 513 1e-143
gi|296140797|ref|YP_003648040.1| hydroxymethylbutenyl pyrophosph... 509 2e-142
gi|333989700|ref|YP_004522314.1| 4-hydroxy-3-methylbut-2-enyl di... 509 3e-142
gi|262201635|ref|YP_003272843.1| hydroxymethylbutenyl pyrophosph... 502 4e-140
gi|343925120|ref|ZP_08764652.1| 4-hydroxy-3-methylbut-2-enyl dip... 478 6e-133
gi|257057116|ref|YP_003134948.1| 4-hydroxy-3-methylbut-2-enyl di... 472 3e-131
gi|302530082|ref|ZP_07282424.1| LytB protein [Streptomyces sp. A... 470 1e-130
gi|317125806|ref|YP_004099918.1| 4-hydroxy-3-methylbut-2-enyl di... 469 2e-130
gi|256374878|ref|YP_003098538.1| 4-hydroxy-3-methylbut-2-enyl di... 468 5e-130
gi|324997965|ref|ZP_08119077.1| 4-hydroxy-3-methylbut-2-enyl dip... 468 8e-130
gi|84494714|ref|ZP_00993833.1| 4-hydroxy-3-methylbut-2-enyl diph... 468 9e-130
gi|326381855|ref|ZP_08203548.1| 4-hydroxy-3-methylbut-2-enyl dip... 466 2e-129
gi|291451500|ref|ZP_06590890.1| 4-hydroxy-3-methylbut-2-enyl dip... 466 2e-129
gi|345001825|ref|YP_004804679.1| hydroxymethylbutenyl pyrophosph... 466 3e-129
gi|291447427|ref|ZP_06586817.1| 4-hydroxy-3-methylbut-2-enyl dip... 466 3e-129
gi|331694831|ref|YP_004331070.1| 4-hydroxy-3-methylbut-2-enyl di... 465 4e-129
gi|317506622|ref|ZP_07964413.1| LytB protein [Segniliparus rugos... 465 4e-129
gi|320008796|gb|ADW03646.1| hydroxymethylbutenyl pyrophosphate r... 463 1e-128
gi|326776894|ref|ZP_08236159.1| 4-hydroxy-3-methylbut-2-enyl dip... 462 3e-128
gi|334336435|ref|YP_004541587.1| 4-hydroxy-3-methylbut-2-enyl di... 462 3e-128
gi|182436265|ref|YP_001823984.1| 4-hydroxy-3-methylbut-2-enyl di... 461 9e-128
gi|297192334|ref|ZP_06909732.1| 4-hydroxy-3-methylbut-2-enyl dip... 461 9e-128
gi|294814789|ref|ZP_06773432.1| 4-hydroxy-3-methylbut-2-enyl dip... 461 1e-127
>gi|308231738|ref|ZP_07413603.2| lytB-related protein lytB2 [Mycobacterium tuberculosis SUMu001]
gi|308370061|ref|ZP_07420157.2| lytB-related protein lytB2 [Mycobacterium tuberculosis SUMu002]
gi|308370619|ref|ZP_07422144.2| lytB-related protein lytB2 [Mycobacterium tuberculosis SUMu003]
24 more sequence titles
Length=344
Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/335 (100%), Positives = 335/335 (100%), Gaps = 0/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV
Sbjct 10 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 69
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT
Sbjct 70 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 129
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE
Sbjct 130 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 189
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 190 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 249
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG
Sbjct 250 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 309
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAECGYDIVQPVTTANETLVFALPRELRSPR
Sbjct 310 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 344
>gi|31792303|ref|NP_854796.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
bovis AF2122/97]
gi|57116829|ref|YP_177788.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
tuberculosis H37Rv]
gi|121637041|ref|YP_977264.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
bovis BCG str. Pasteur 1173P2]
51 more sequence titles
Length=335
Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/335 (100%), Positives = 335/335 (100%), Gaps = 0/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV
Sbjct 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT
Sbjct 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE
Sbjct 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG
Sbjct 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAECGYDIVQPVTTANETLVFALPRELRSPR
Sbjct 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
>gi|15840547|ref|NP_335584.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
tuberculosis CDC1551]
gi|13880725|gb|AAK45398.1| lytB protein [Mycobacterium tuberculosis CDC1551]
Length=329
Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/329 (100%), Positives = 329/329 (100%), Gaps = 0/329 (0%)
Query 7 MGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVH 66
MGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVH
Sbjct 1 MGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVH 60
Query 67 NRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTK 126
NRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTK
Sbjct 61 NRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTK 120
Query 127 VHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWL 186
VHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWL
Sbjct 121 VHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWL 180
Query 187 SQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRN 246
SQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRN
Sbjct 181 SQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRN 240
Query 247 SSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLA 306
SSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLA
Sbjct 241 SSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLA 300
Query 307 ECGYDIVQPVTTANETLVFALPRELRSPR 335
ECGYDIVQPVTTANETLVFALPRELRSPR
Sbjct 301 ECGYDIVQPVTTANETLVFALPRELRSPR 329
>gi|240171091|ref|ZP_04749750.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
kansasii ATCC 12478]
Length=335
Score = 616 bits (1588), Expect = 2e-174, Method: Compositional matrix adjust.
Identities = 305/335 (92%), Positives = 320/335 (96%), Gaps = 0/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPTVDMGIPGAS S SVA+ P KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYV
Sbjct 1 MVPTVDMGIPGASRSVSSVANAPTHKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYV 60
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct 61 RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 120
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGV AVDQVTVRDE
Sbjct 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVQAVDQVTVRDE 180
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KVVWLSQTTLSVDETMEIV +LR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVI
Sbjct 181 NKVVWLSQTTLSVDETMEIVEKLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECQLVI 240
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALGAGA+AAHLVDWADDID AWL+GVTTVGVTSGASVPEVLVRG
Sbjct 241 VVGSRNSSNSVRLVEVALGAGAKAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVRG 300
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAE G+D+VQPVTTANETLVFALPRE+R R
Sbjct 301 VLERLAELGFDMVQPVTTANETLVFALPREIRPAR 335
>gi|183984326|ref|YP_001852617.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Mycobacterium
marinum M]
gi|183177652|gb|ACC42762.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Mycobacterium
marinum M]
Length=332
Score = 602 bits (1552), Expect = 3e-170, Method: Compositional matrix adjust.
Identities = 296/335 (89%), Positives = 318/335 (95%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPT+DMGIPGAS SVA P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct 1 MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct 58 RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D ++VT+RDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+LV+
Sbjct 178 EKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVL 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALGAGA+AA+LVDWADDID +WL GVTTVGVTSGASVPEVLVRG
Sbjct 238 VVGSRNSSNSVRLVEVALGAGAQAAYLVDWADDIDQSWLQGVTTVGVTSGASVPEVLVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAE GYD+VQPVTTANETLVFALPRE+R R
Sbjct 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
>gi|118616061|ref|YP_904393.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
ulcerans Agy99]
gi|166217175|sp|A0PKQ3.1|ISPH_MYCUA RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|118568171|gb|ABL02922.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Mycobacterium
ulcerans Agy99]
Length=332
Score = 601 bits (1550), Expect = 5e-170, Method: Compositional matrix adjust.
Identities = 297/335 (89%), Positives = 317/335 (95%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPT+DMGIPGAS SVA P R+RVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct 1 MVPTIDMGIPGAS---SSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEET+QVPEGAIVVFSAHGVAPTV+ +A+ERNLQ IDAT
Sbjct 58 RHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAP+HVQLVDG+D V++VT+RDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGVERVTIRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIV RLR+RF KLQDPPSDDICYATQNRQVAVKAMAPEC+LV+
Sbjct 178 DKVVWLSQTTLSVDETMEIVARLRQRFAKLQDPPSDDICYATQNRQVAVKAMAPECDLVL 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALGAGA AA+LVDWADDID +WL GVTTVGVTSGASVPEVLVRG
Sbjct 238 VVGSRNSSNSVRLVEVALGAGAEAAYLVDWADDIDQSWLQGVTTVGVTSGASVPEVLVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAE GYD+VQPVTTANETLVFALPRE+R R
Sbjct 298 VLERLAESGYDMVQPVTTANETLVFALPREIRPAR 332
>gi|254774114|ref|ZP_05215630.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
avium subsp. avium ATCC 25291]
Length=332
Score = 587 bits (1514), Expect = 7e-166, Method: Compositional matrix adjust.
Identities = 301/335 (90%), Positives = 315/335 (95%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTVDMGIPGAS SVA P+RKRVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct 1 MPPTVDMGIPGAS---SSVAVNPSRKRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV TL KAGAVFVEET++VPEGAIVVFSAHGVAPTVH +A+ERNL IDAT
Sbjct 58 RHEIVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAHGVAPTVHAAAAERNLHTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAPDHVQLVDGV AVD VTVRDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVAAVDNVTVRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVI
Sbjct 178 DKVVWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALG GA AAHLVDWADDID AWL+GVTTVGVTSGASVPEVLV+G
Sbjct 238 VVGSRNSSNSVRLVEVALGGGAGAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVQG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAECG+D+VQPVTTA ETLVFALPRE+RS R
Sbjct 298 VLERLAECGFDVVQPVTTAQETLVFALPREIRSAR 332
>gi|41408782|ref|NP_961618.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
avium subsp. paratuberculosis K-10]
gi|50400912|sp|Q73WH6.1|ISPH_MYCPA RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|41397140|gb|AAS05001.1| LytB' [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336458725|gb|EGO37685.1| (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase [Mycobacterium
avium subsp. paratuberculosis S397]
Length=332
Score = 584 bits (1506), Expect = 6e-165, Method: Compositional matrix adjust.
Identities = 300/335 (90%), Positives = 313/335 (94%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTVDMGIPGAS SVA P RKRVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct 1 MPPTVDMGIPGAS---SSVAVNPTRKRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV TL KAGAVFVEET++VPEGAIVVFSAHGVAPTVH +A+ERNL IDAT
Sbjct 58 RHEIVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAHGVAPTVHAAAAERNLHTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAPDHVQLVDGV AVD V VRDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVAAVDNVRVRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVI
Sbjct 178 DKVVWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALG GA AAHLVDWADDID AWL+GVTTVGVTSGASVPEVLV+G
Sbjct 238 VVGSRNSSNSVRLVEVALGGGAGAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVQG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAECG+D+VQPVTTA ETLVFALPRE+RS R
Sbjct 298 VLERLAECGFDVVQPVTTAQETLVFALPREIRSAR 332
>gi|254819702|ref|ZP_05224703.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
intracellulare ATCC 13950]
Length=332
Score = 581 bits (1498), Expect = 5e-164, Method: Compositional matrix adjust.
Identities = 299/335 (90%), Positives = 313/335 (94%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M TVDMGIPGA+ SVA P RKRVLLAEPRGYCAGVDRAVETVERAL+KHGPPVYV
Sbjct 1 MPSTVDMGIPGAA---SSVAVPPTRKRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV TL KAGAVFVEET++VPEGAIVVFSAHGVAP+VH +A+ERNL IDAT
Sbjct 58 RHEIVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAHGVAPSVHSAAAERNLHTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEAPDHVQLVDGV AVD VTVRDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVAAVDNVTVRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 DKVVWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALG GA AAHLVDWADDID AWL+GVTTVGVTSGASVPEVLV+G
Sbjct 238 VVGSRNSSNSVRLVEVALGGGAAAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVQG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VLERLAECG+D+VQPVTTA ETLVFALPRE+RS R
Sbjct 298 VLERLAECGFDLVQPVTTAQETLVFALPREIRSAR 332
>gi|296169976|ref|ZP_06851583.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
parascrofulaceum ATCC BAA-614]
gi|295895380|gb|EFG75086.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
parascrofulaceum ATCC BAA-614]
Length=332
Score = 572 bits (1474), Expect = 3e-161, Method: Compositional matrix adjust.
Identities = 293/333 (88%), Positives = 311/333 (94%), Gaps = 3/333 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTVDMGIPGAS SVA P RKRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYV
Sbjct 1 MPPTVDMGIPGAS---SSVASDPARKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV TL +AGAVFVEET++VPEG+IVVFSAHGVAPTV+ +A+ERNL IDAT
Sbjct 58 RHEIVHNRHVVTTLEQAGAVFVEETDEVPEGSIVVFSAHGVAPTVYAAAAERNLHTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFAR+DYDILLIGHEGHEEV+GT+GEAPDHVQLVDGV AVD VTVRDE
Sbjct 118 CPLVTKVHNEARRFARNDYDILLIGHEGHEEVIGTSGEAPDHVQLVDGVAAVDNVTVRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVI
Sbjct 178 NKVVWLSQTTLSVDETMEIVDRLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECQLVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVALG GA AAHLVDWADDID AWL+GVTTVGVTSGASVPEVLVRG
Sbjct 238 VVGSRNSSNSVRLVEVALGGGAAAAHLVDWADDIDPAWLEGVTTVGVTSGASVPEVLVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRS 333
VLERLAE G+D+VQPVTTA ETLVFALPRE+RS
Sbjct 298 VLERLAEHGFDVVQPVTTAQETLVFALPREIRS 330
>gi|145222667|ref|YP_001133345.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
gilvum PYR-GCK]
gi|189045812|sp|A4T986.1|ISPH_MYCGI RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|145215153|gb|ABP44557.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
gilvum PYR-GCK]
Length=333
Score = 571 bits (1471), Expect = 6e-161, Method: Compositional matrix adjust.
Identities = 282/335 (85%), Positives = 308/335 (92%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTV+MGIPGA+ SV +R KRVLLAEPRGYCAGVDRAVETVERAL+KHG P+YV
Sbjct 1 MPPTVNMGIPGAA---SSVVERTAGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPIYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNR+VVDTLAKAGA+FVE+T++VPEGAIVVFSAHGVAPTVHV A+ RNL+ IDAT
Sbjct 58 RHEIVHNRYVVDTLAKAGAIFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEA+RFARDDYDILL+GHEGHEEVVGTAGEAPDHVQ+VD DAVD V VRD
Sbjct 118 CPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDNVVVRDP 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KV+WLSQTTLSVDETME V RLR +FP LQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 NKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGS+NSSNSVRLVEVALGAG+RAAHLVD+A+DID AWLDGVTTVGVTSGASVPE+LVRG
Sbjct 238 VVGSKNSSNSVRLVEVALGAGSRAAHLVDYAEDIDPAWLDGVTTVGVTSGASVPEILVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VL+RLAE G+D VQPVTTANETLVFALPRE+R R
Sbjct 298 VLDRLAEHGFDTVQPVTTANETLVFALPREIRPAR 332
>gi|120405583|ref|YP_955412.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
vanbaalenii PYR-1]
gi|166217176|sp|A1TE06.1|ISPH_MYCVP RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|119958401|gb|ABM15406.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
vanbaalenii PYR-1]
Length=337
Score = 568 bits (1465), Expect = 3e-160, Method: Compositional matrix adjust.
Identities = 283/336 (85%), Positives = 309/336 (92%), Gaps = 1/336 (0%)
Query 1 MVPTVDMGIPGASVSSR-SVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVY 59
M PTV+MGIPGAS ++ SVA KRVLLAEPRGYCAGVDRAVETVERAL+KHG P+Y
Sbjct 1 MPPTVNMGIPGASRTALGSVAGDVTGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPIY 60
Query 60 VRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDA 119
VRHEIVHNR+VVDTLAKAGA+FVE+T++VPEGAIVVFSAHGVAPTVH A+ R+L+ IDA
Sbjct 61 VRHEIVHNRYVVDTLAKAGAIFVEQTDEVPEGAIVVFSAHGVAPTVHEEAAARHLRTIDA 120
Query 120 TCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRD 179
TCPLVTKVHNEA+RFARDDYDILL+GHEGHEEVVGTAGEAPDHVQ+VD DAVD+VTVRD
Sbjct 121 TCPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRD 180
Query 180 EDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELV 239
+KV+WLSQTTLSVDETME V RLR +FP LQDPPSDDICYATQNRQVAVKAMAPECELV
Sbjct 181 PNKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELV 240
Query 240 IVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVR 299
IVVGS+NSSNSVRLVEVALGAGA AAHLVD+ADDID AW DGVTTVGVTSGASVPE+LVR
Sbjct 241 IVVGSKNSSNSVRLVEVALGAGASAAHLVDYADDIDPAWFDGVTTVGVTSGASVPEILVR 300
Query 300 GVLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
GVL+RLAE GYD+VQPVTTANETLVFALPRE+R R
Sbjct 301 GVLDRLAEHGYDVVQPVTTANETLVFALPREIRPAR 336
>gi|126436907|ref|YP_001072598.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. JLS]
gi|166217173|sp|A3Q4N0.1|ISPH_MYCSJ RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|126236707|gb|ABO00108.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. JLS]
Length=333
Score = 568 bits (1465), Expect = 3e-160, Method: Compositional matrix adjust.
Identities = 284/335 (85%), Positives = 306/335 (92%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PT++MGIPGAS SV + KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYV
Sbjct 1 MPPTINMGIPGAS---SSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNR+VVDTLAKAGAVFVE+T++VPEGAIVVFSAHGVAPTVHV A+ RNL+ IDAT
Sbjct 58 RHEIVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEA+RFARDDYDILL+GHEGHEEVVGTAGEAPDHVQ+VD DAVD+VTVRD
Sbjct 118 CPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDP 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKV+WLSQTTLSVDETME V RLR +FP LQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 DKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGS+NSSNSVRLVEVALGAG+ AAHLVD+A+DID WLDGVTTVGVTSGASVPEVLVRG
Sbjct 238 VVGSKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLDGVTTVGVTSGASVPEVLVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VL+RLAE GY VQPVTTANETLVFALPRE+R R
Sbjct 298 VLDRLAEYGYGTVQPVTTANETLVFALPREIRPAR 332
>gi|315443130|ref|YP_004076009.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. Spyr1]
gi|315261433|gb|ADT98174.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. Spyr1]
Length=333
Score = 568 bits (1464), Expect = 5e-160, Method: Compositional matrix adjust.
Identities = 281/335 (84%), Positives = 306/335 (92%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTV+MGIPGA+ SV +R KRVLLAEPRGYCAGVDRAVETVERAL+KHG P+YV
Sbjct 1 MPPTVNMGIPGAA---SSVVERTAGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPIYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNR+VVDTLAKAGA+FVE+T++VPEGAIVVFSAHGVAPTVHV A+ RNLQ IDAT
Sbjct 58 RHEIVHNRYVVDTLAKAGAIFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLQTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEA+RFARDDYDILL+GHEGHEEVVGTAGEAPDHVQ+VD DAVD V VRD
Sbjct 118 CPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDNVVVRDP 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KV+WLSQTTLSVDETME V RLR +FP LQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 NKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGS+NSSNSVRLVEVALGAG+ AAHLVD+A+D D AWLDGVTTVGVTSGASVPE+LVRG
Sbjct 238 VVGSKNSSNSVRLVEVALGAGSHAAHLVDYAEDTDPAWLDGVTTVGVTSGASVPEILVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VL+RLAE G+D VQPVTTANETLVFALPRE+R R
Sbjct 298 VLDRLAEHGFDTVQPVTTANETLVFALPREIRPAR 332
>gi|108801069|ref|YP_641266.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. MCS]
gi|119870211|ref|YP_940163.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. KMS]
gi|123069758|sp|Q1B4H4.1|ISPH_MYCSS RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|166217174|sp|A1UKL5.1|ISPH_MYCSK RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|108771488|gb|ABG10210.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. MCS]
gi|119696300|gb|ABL93373.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
sp. KMS]
Length=333
Score = 567 bits (1462), Expect = 8e-160, Method: Compositional matrix adjust.
Identities = 283/335 (85%), Positives = 306/335 (92%), Gaps = 3/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PT++MGIPGAS SV + KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYV
Sbjct 1 MPPTINMGIPGAS---SSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNR+VVDTLAKAGAVFVE+T++VPEGAIVVFSAHGVAPTVHV A+ RNL+ IDAT
Sbjct 58 RHEIVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEA+RFARDDYDILL+GHEGHEEVVGTAGEAPDHVQ+VD DAVD+VTVRD
Sbjct 118 CPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDP 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKV+WLSQTTLSVDETME V RLR +FP LQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 DKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGS+NSSNSVRLVEVALGAG+ AAHLVD+A+DID WL+GVTTVGVTSGASVPEVLVRG
Sbjct 238 VVGSKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLNGVTTVGVTSGASVPEVLVRG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VL+RLAE GY VQPVTTANETLVFALPRE+R R
Sbjct 298 VLDRLAEYGYGTVQPVTTANETLVFALPREIRPAR 332
>gi|118473320|ref|YP_889470.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
smegmatis str. MC2 155]
gi|118174607|gb|ABK75503.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
smegmatis str. MC2 155]
Length=314
Score = 563 bits (1452), Expect = 1e-158, Method: Compositional matrix adjust.
Identities = 277/310 (90%), Positives = 295/310 (96%), Gaps = 0/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYVRHEIVHNRHVV+TLAKAGA+FV+ET
Sbjct 4 KRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEIVHNRHVVETLAKAGAIFVDET 63
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEGAIVVFSAHGVAPTVH SA+ERNL+VIDATCPLVTKVHNEA+RFARDDYDILLIG
Sbjct 64 DEVPEGAIVVFSAHGVAPTVHQSAAERNLKVIDATCPLVTKVHNEAKRFARDDYDILLIG 123
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEVVGTAGEAPDHVQLVDG ++VD VTVRDE KV+WLSQTTLSVDETME V RLR
Sbjct 124 HEGHEEVVGTAGEAPDHVQLVDGPESVDAVTVRDESKVIWLSQTTLSVDETMETVRRLRE 183
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP LQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVAL AG+ AA
Sbjct 184 KFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALNAGSDAA 243
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+ADDID AWLDGVTT+GVTSGASVPE+LVRGVLERLAE GYD VQPVTTANETLVF
Sbjct 244 HLVDYADDIDPAWLDGVTTIGVTSGASVPEILVRGVLERLAEHGYDTVQPVTTANETLVF 303
Query 326 ALPRELRSPR 335
ALPRE+R PR
Sbjct 304 ALPREIRPPR 313
>gi|169628350|ref|YP_001701999.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
abscessus ATCC 19977]
gi|169240317|emb|CAM61345.1| Probable 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
abscessus]
Length=337
Score = 561 bits (1447), Expect = 4e-158, Method: Compositional matrix adjust.
Identities = 278/331 (84%), Positives = 301/331 (91%), Gaps = 0/331 (0%)
Query 5 VDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEI 64
VDMG PG ++ KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYVRHEI
Sbjct 4 VDMGTPGMVSTAMRTVGPAISKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEI 63
Query 65 VHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLV 124
VHNR+VVDTLAKAGA+FV+ET++VPEGAIVVFSAHGVAPTVH A+ERNL+ IDATCPLV
Sbjct 64 VHNRYVVDTLAKAGAIFVDETDEVPEGAIVVFSAHGVAPTVHEKAAERNLKTIDATCPLV 123
Query 125 TKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVV 184
TKVH EA+RFARDD+DILLIGHEGHEEV+GTAGEAPDHVQLVDG +AVD VTVRDE+KV+
Sbjct 124 TKVHQEAKRFARDDFDILLIGHEGHEEVIGTAGEAPDHVQLVDGPNAVDNVTVRDENKVI 183
Query 185 WLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS 244
WLSQTTLSVDETME V RLR RFP LQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS
Sbjct 184 WLSQTTLSVDETMETVQRLRERFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS 243
Query 245 RNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLER 304
RNSSNSVRLVEVAL AG+RA++LVD+A+DID AWL+GVTTVGVTSGASVPEVLVRGVLER
Sbjct 244 RNSSNSVRLVEVALNAGSRASYLVDYAEDIDPAWLEGVTTVGVTSGASVPEVLVRGVLER 303
Query 305 LAECGYDIVQPVTTANETLVFALPRELRSPR 335
LAE GY VQPVTTANETLVFALPRELR+ R
Sbjct 304 LAEHGYGEVQPVTTANETLVFALPRELRASR 334
>gi|15828043|ref|NP_302306.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
leprae TN]
gi|221230520|ref|YP_002503936.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
leprae Br4923]
gi|4539094|emb|CAB39812.1| lytB homolog [Mycobacterium leprae]
gi|13093596|emb|CAC30893.1| LytB homolog [Mycobacterium leprae]
gi|219933627|emb|CAR72035.1| LytB homolog [Mycobacterium leprae Br4923]
Length=335
Score = 561 bits (1445), Expect = 7e-158, Method: Compositional matrix adjust.
Identities = 276/333 (83%), Positives = 305/333 (92%), Gaps = 3/333 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTV+MGIPGAS RS+ + RKRVLLAEPRGYCAGVDRAVETVER+L+K+GPPVYV
Sbjct 4 MPPTVNMGIPGAS---RSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYV 60
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV+TL +AGAVFVEET+ VPEGAIV+FSAHGVAPTV+ +A+ERNL+ IDAT
Sbjct 61 RHEIVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDAT 120
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNE +RFAR+DYDILLIGHEGHEEV+ TAGEAP HVQLVDG+ AV QV VRDE
Sbjct 121 CPLVTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDE 180
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KVVWLSQTTLSVDETM IV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 181 NKVVWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVA+G+GA AA+LVDWA DID AWL GVTTVGVTSGASVP++LV+G
Sbjct 241 VVGSRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQG 300
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRS 333
VL+ LAE GYD+VQ VTTANE LVFALPRE+RS
Sbjct 301 VLKWLAERGYDVVQSVTTANEALVFALPREIRS 333
>gi|8928200|sp|Q9X781.2|ISPH_MYCLE RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Length=332
Score = 560 bits (1444), Expect = 9e-158, Method: Compositional matrix adjust.
Identities = 276/333 (83%), Positives = 305/333 (92%), Gaps = 3/333 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M PTV+MGIPGAS RS+ + RKRVLLAEPRGYCAGVDRAVETVER+L+K+GPPVYV
Sbjct 1 MPPTVNMGIPGAS---RSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYV 57
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVV+TL +AGAVFVEET+ VPEGAIV+FSAHGVAPTV+ +A+ERNL+ IDAT
Sbjct 58 RHEIVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDAT 117
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNE +RFAR+DYDILLIGHEGHEEV+ TAGEAP HVQLVDG+ AV QV VRDE
Sbjct 118 CPLVTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDE 177
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KVVWLSQTTLSVDETM IV RLR+RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 178 NKVVWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 237
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVA+G+GA AA+LVDWA DID AWL GVTTVGVTSGASVP++LV+G
Sbjct 238 VVGSRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQG 297
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRS 333
VL+ LAE GYD+VQ VTTANE LVFALPRE+RS
Sbjct 298 VLKWLAERGYDVVQSVTTANEALVFALPREIRS 330
>gi|342861699|ref|ZP_08718345.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
colombiense CECT 3035]
gi|342130833|gb|EGT84129.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
colombiense CECT 3035]
Length=308
Score = 554 bits (1427), Expect = 9e-156, Method: Compositional matrix adjust.
Identities = 281/308 (92%), Positives = 292/308 (95%), Gaps = 0/308 (0%)
Query 28 VLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQ 87
+LLAEPRGYCAGVDRAVETVERAL+KHGPPVYVRHEIVHNRHVV TL KAGAVFVEET++
Sbjct 1 MLLAEPRGYCAGVDRAVETVERALKKHGPPVYVRHEIVHNRHVVTTLEKAGAVFVEETDE 60
Query 88 VPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHE 147
VPEGAIVVFSAHGVAPTVH +A+ERNL IDATCPLVTKVHNEARRFAR+DYDILLIGHE
Sbjct 61 VPEGAIVVFSAHGVAPTVHAAAAERNLHTIDATCPLVTKVHNEARRFARNDYDILLIGHE 120
Query 148 GHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRF 207
GHEEVVGTAGEAPDHVQLVDGV AVD VTVRDE+KVVWLSQTTLSVDETMEIV RLR RF
Sbjct 121 GHEEVVGTAGEAPDHVQLVDGVAAVDNVTVRDENKVVWLSQTTLSVDETMEIVERLRERF 180
Query 208 PKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHL 267
PKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALG GA AAHL
Sbjct 181 PKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGGGAAAAHL 240
Query 268 VDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFAL 327
VDWADDID AWL+GVTTVGVTSGASVPEVLV GVL RLAECGYD+VQPVTTA ETLVFAL
Sbjct 241 VDWADDIDPAWLEGVTTVGVTSGASVPEVLVEGVLSRLAECGYDVVQPVTTAQETLVFAL 300
Query 328 PRELRSPR 335
PRE+RS R
Sbjct 301 PREIRSAR 308
>gi|289761249|ref|ZP_06520627.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
tuberculosis GM 1503]
gi|289708755|gb|EFD72771.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
tuberculosis GM 1503]
Length=278
Score = 542 bits (1396), Expect = 3e-152, Method: Compositional matrix adjust.
Identities = 269/269 (100%), Positives = 269/269 (100%), Gaps = 0/269 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV
Sbjct 10 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 69
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT
Sbjct 70 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 129
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE
Sbjct 130 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 189
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI
Sbjct 190 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 249
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVD 269
VVGSRNSSNSVRLVEVALGAGARAAHLVD
Sbjct 250 VVGSRNSSNSVRLVEVALGAGARAAHLVD 278
>gi|118464410|ref|YP_880476.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
avium 104]
gi|118165697|gb|ABK66594.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Mycobacterium
avium 104]
Length=296
Score = 529 bits (1363), Expect = 2e-148, Method: Compositional matrix adjust.
Identities = 269/296 (91%), Positives = 283/296 (96%), Gaps = 0/296 (0%)
Query 40 VDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAH 99
+DRAVETVERAL+KHGPPVYVRHEIVHNRHVV TL KAGAVFVEET++VPEGAIVVFSAH
Sbjct 1 MDRAVETVERALEKHGPPVYVRHEIVHNRHVVSTLEKAGAVFVEETDEVPEGAIVVFSAH 60
Query 100 GVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEA 159
GVAPTVH +A+ERNL IDATCPLVTKVHNEARRFAR+DYDILLIGHEGHEEVVGTAGEA
Sbjct 61 GVAPTVHAAAAERNLHTIDATCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEA 120
Query 160 PDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDIC 219
PDHVQLVDGV AVD VTVRDEDKVVWLSQTTLSVDETMEIV RLR+RFPKLQDPPSDDIC
Sbjct 121 PDHVQLVDGVAAVDNVTVRDEDKVVWLSQTTLSVDETMEIVERLRQRFPKLQDPPSDDIC 180
Query 220 YATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWL 279
YATQNRQVAVKAMAPEC+LVIVVGSRNSSNSVRLVEVALG GA AAHLVDWADDID AWL
Sbjct 181 YATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALGGGAGAAHLVDWADDIDPAWL 240
Query 280 DGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
+GVTTVGVTSGASVPEVLV+GVLERLAECG+D+VQPVTTA ETLVFALPRE+RS R
Sbjct 241 EGVTTVGVTSGASVPEVLVQGVLERLAECGFDVVQPVTTAQETLVFALPREIRSAR 296
>gi|312138756|ref|YP_004006092.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
equi 103S]
gi|325676551|ref|ZP_08156229.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
equi ATCC 33707]
gi|311888095|emb|CBH47407.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
equi 103S]
gi|325552729|gb|EGD22413.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
equi ATCC 33707]
Length=334
Score = 523 bits (1346), Expect = 2e-146, Method: Compositional matrix adjust.
Identities = 253/310 (82%), Positives = 285/310 (92%), Gaps = 0/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLAEPRGYCAGVDRAVETVE+AL+KHG P+YVR EIVHNRHVVDTLA+ G VFV+ET
Sbjct 24 KRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVHNRHVVDTLAERGVVFVDET 83
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPE +++VFSAHGV+P VH +A+ER+L IDATCPLVTKVH EA+RFARDDYDILLIG
Sbjct 84 DEVPENSVLVFSAHGVSPAVHTAAAERSLHTIDATCPLVTKVHQEAKRFARDDYDILLIG 143
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAP+HVQ+VDG D+VD +TVRDEDKV+WLSQTTLSVDETME V RLR
Sbjct 144 HEGHEEVEGTAGEAPEHVQIVDGPDSVDAITVRDEDKVIWLSQTTLSVDETMETVERLRE 203
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGSRNSSNSVRLVEVALGAGARAA
Sbjct 204 KFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALGAGARAA 263
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+A ++D AWL+GV TVG+TSGASVPE+LVRGV++ LAE G+ VQ VTTANETLVF
Sbjct 264 HLVDFAREVDLAWLEGVRTVGITSGASVPEILVRGVIDLLAEHGFADVQSVTTANETLVF 323
Query 326 ALPRELRSPR 335
ALPRELR+ R
Sbjct 324 ALPRELRAAR 333
>gi|226365341|ref|YP_002783124.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
opacus B4]
gi|254806912|sp|C1AYI4.1|ISPH_RHOOB RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|226243831|dbj|BAH54179.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
opacus B4]
Length=336
Score = 522 bits (1345), Expect = 3e-146, Method: Compositional matrix adjust.
Identities = 258/331 (78%), Positives = 294/331 (89%), Gaps = 2/331 (0%)
Query 5 VDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEI 64
+++GI ++ S S AD KRVLLAEPRGYCAGVDRAVETVE+AL+KHG P+YVR EI
Sbjct 7 LNVGITRSADSGASRAD--GEKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEI 64
Query 65 VHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLV 124
VHNRHVV+TL+ G VFV+ET++VPEGA++VFSAHGV+P VH SA+ RNL+ IDATCPLV
Sbjct 65 VHNRHVVETLSDQGVVFVDETDEVPEGALLVFSAHGVSPAVHESAAARNLRTIDATCPLV 124
Query 125 TKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVV 184
TKVH EA+RFARDD+DILLIGHEGHEEV GTAGEAPDHVQLVDG D+VD VTVRDE KV+
Sbjct 125 TKVHQEAKRFARDDFDILLIGHEGHEEVEGTAGEAPDHVQLVDGPDSVDAVTVRDESKVI 184
Query 185 WLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS 244
WLSQTTLSVDETM+ V RLR RFP LQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGS
Sbjct 185 WLSQTTLSVDETMQTVARLRERFPSLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGS 244
Query 245 RNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLER 304
RNSSNSVRLVEVALGAGA+A++LVD+A ++D AWLDGV TVG+TSGASVPE+LVRGV++
Sbjct 245 RNSSNSVRLVEVALGAGAKASYLVDYAREVDPAWLDGVRTVGITSGASVPEILVRGVIDL 304
Query 305 LAECGYDIVQPVTTANETLVFALPRELRSPR 335
L E G+ VQPVTTANETLVFALPRELR+ R
Sbjct 305 LDEHGFHDVQPVTTANETLVFALPRELRAAR 335
>gi|226307721|ref|YP_002767681.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
erythropolis PR4]
gi|229493946|ref|ZP_04387718.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
erythropolis SK121]
gi|259493953|sp|C1A2V7.1|ISPH_RHOE4 RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|226186838|dbj|BAH34942.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
erythropolis PR4]
gi|229319223|gb|EEN85072.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
erythropolis SK121]
Length=337
Score = 522 bits (1344), Expect = 4e-146, Method: Compositional matrix adjust.
Identities = 253/310 (82%), Positives = 283/310 (92%), Gaps = 0/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLAEPRGYCAGVDRAVETVE+AL+KHG P+YVR EIVHNRHVV+TL G +FV+ET
Sbjct 26 KRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVHNRHVVETLEDQGVIFVDET 85
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEG+++VFSAHGV+P VH SA+ERNL+ IDATCPLVTKVH EA+RFARDDYDILLIG
Sbjct 86 DEVPEGSLLVFSAHGVSPAVHDSAAERNLRTIDATCPLVTKVHQEAKRFARDDYDILLIG 145
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAPDHV +VDG D+VD VTVRDE KV+WLSQTTLSVDETM+ V RLR
Sbjct 146 HEGHEEVEGTAGEAPDHVTIVDGPDSVDAVTVRDESKVIWLSQTTLSVDETMQTVARLRE 205
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
RFP LQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGSRNSSNSVRLVEVALGAGA A+
Sbjct 206 RFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALGAGAAAS 265
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
+LVD+A ++D AWL+GV TVG+TSGASVPEVLVRGV+E LAE GY+ VQPVTTANETLVF
Sbjct 266 YLVDYAREVDLAWLEGVQTVGITSGASVPEVLVRGVIELLAEHGYNDVQPVTTANETLVF 325
Query 326 ALPRELRSPR 335
ALPRELR+ R
Sbjct 326 ALPRELRAAR 335
>gi|111022833|ref|YP_705805.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
jostii RHA1]
gi|123339839|sp|Q0S489.1|ISPH_RHOSR RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|110822363|gb|ABG97647.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Rhodococcus
jostii RHA1]
Length=336
Score = 521 bits (1343), Expect = 4e-146, Method: Compositional matrix adjust.
Identities = 258/331 (78%), Positives = 292/331 (89%), Gaps = 2/331 (0%)
Query 5 VDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEI 64
+++GI ++ S S AD KRVLLAEPRGYCAGVDRAVETVE+AL+KHG P+YVR EI
Sbjct 7 LNVGITRSADSGASRAD--GEKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEI 64
Query 65 VHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLV 124
VHNRHVVDTL G VFV+ET++VPEGA++VFSAHGV+P VH SA+ RNL+ IDATCPLV
Sbjct 65 VHNRHVVDTLTDQGVVFVDETDEVPEGALLVFSAHGVSPAVHESAAARNLRTIDATCPLV 124
Query 125 TKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVV 184
TKVH EA+RFARDD+DILLIGHEGHEEV GTAGEAPDHVQLVDG D+VD VTVRDE KV+
Sbjct 125 TKVHQEAKRFARDDFDILLIGHEGHEEVEGTAGEAPDHVQLVDGPDSVDAVTVRDESKVI 184
Query 185 WLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGS 244
WLSQTTLSVDETM+ V RLR RFP LQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGS
Sbjct 185 WLSQTTLSVDETMQTVARLRERFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGS 244
Query 245 RNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLER 304
RNSSNSVRLVEVAL AGA+A++LVD+A ++D AWLDGV TVG+TSGASVPE+LVRGV++
Sbjct 245 RNSSNSVRLVEVALNAGAKASYLVDYAREVDPAWLDGVRTVGITSGASVPEILVRGVIDL 304
Query 305 LAECGYDIVQPVTTANETLVFALPRELRSPR 335
L E G+ VQPVTTANETLVFALPRELR+ R
Sbjct 305 LDEHGFHDVQPVTTANETLVFALPRELRAAR 335
>gi|54026769|ref|YP_121011.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Nocardia
farcinica IFM 10152]
gi|71152191|sp|Q5YQ94.1|ISPH_NOCFA RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|54018277|dbj|BAD59647.1| putative isoprenoid biosynthesis protein [Nocardia farcinica
IFM 10152]
Length=336
Score = 521 bits (1342), Expect = 6e-146, Method: Compositional matrix adjust.
Identities = 257/335 (77%), Positives = 290/335 (87%), Gaps = 0/335 (0%)
Query 1 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV 60
M + + + A + + D KRVLLAEPRGYCAGVDRAVETVE+AL+KHG P+YV
Sbjct 1 MSSAIPLNVGIARSAGTATVDADTAKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYV 60
Query 61 RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT 120
R EIVHNRHVV+TL + G VFV++T +VPEGA+VVFSAHGV+P VH +A+ RNL IDAT
Sbjct 61 RKEIVHNRHVVETLRERGVVFVDDTAEVPEGAVVVFSAHGVSPAVHEAAAARNLHTIDAT 120
Query 121 CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE 180
CPLVTKVH EA+RFARDDYDILLIGHEGHEEV GTAGEAP+HVQLVDG DAVD+V VRDE
Sbjct 121 CPLVTKVHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPEHVQLVDGPDAVDRVRVRDE 180
Query 181 DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI 240
+KV+WLSQTTLSVDETME V RLR RFP LQDPPSDDICYATQNRQVAVKAMAPEC+LVI
Sbjct 181 NKVIWLSQTTLSVDETMETVQRLRERFPSLQDPPSDDICYATQNRQVAVKAMAPECDLVI 240
Query 241 VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG 300
VVGSRNSSNSVRLVEVAL AGA+AAHLVD+A ++D AWL+GV T+G+TSGASVPE+LVRG
Sbjct 241 VVGSRNSSNSVRLVEVALNAGAKAAHLVDYAREVDPAWLEGVRTIGITSGASVPEILVRG 300
Query 301 VLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
VL+ LAE GY VQPVTTANETLVFALPRELR+ R
Sbjct 301 VLDMLAEHGYADVQPVTTANETLVFALPRELRTTR 335
>gi|333921058|ref|YP_004494639.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Amycolicicoccus
subflavus DQS3-9A1]
gi|333483279|gb|AEF41839.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Amycolicicoccus
subflavus DQS3-9A1]
Length=328
Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust.
Identities = 258/329 (79%), Positives = 288/329 (88%), Gaps = 3/329 (0%)
Query 7 MGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVH 66
MGIPGA S+ S +P KRVLLAEPRGYCAGVDRAVETVERAL+KHG PVYVR EIVH
Sbjct 1 MGIPGAVNSAVS---KPQGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRKEIVH 57
Query 67 NRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTK 126
NRHVV+TL++ GAVFVEE ++VPEGA+VVFSAHGV+P VH +A R L+ IDATCPLVTK
Sbjct 58 NRHVVETLSERGAVFVEEVDEVPEGALVVFSAHGVSPAVHEAAGTRELRTIDATCPLVTK 117
Query 127 VHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWL 186
VH EA+RFARDD+DILLIGHEGHEEV GTAGEAP HVQLVDG D+VD+V VRDE +VVWL
Sbjct 118 VHQEAKRFARDDFDILLIGHEGHEEVEGTAGEAPSHVQLVDGPDSVDKVEVRDESRVVWL 177
Query 187 SQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRN 246
SQTTLSVDETME V RLR+RFP LQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGSRN
Sbjct 178 SQTTLSVDETMETVERLRKRFPGLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRN 237
Query 247 SSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLA 306
SSNS+RLVEVAL AGAR ++LVD+A +I+ AWL+GV TVGVTSGASVPE+LV GVL+ L+
Sbjct 238 SSNSLRLVEVALDAGARTSYLVDYAKEINPAWLEGVETVGVTSGASVPEILVDGVLQFLS 297
Query 307 ECGYDIVQPVTTANETLVFALPRELRSPR 335
G+ VQ VTTANETLVFALPRELR R
Sbjct 298 GEGFGTVQTVTTANETLVFALPRELRPSR 326
>gi|296140797|ref|YP_003648040.1| hydroxymethylbutenyl pyrophosphate reductase [Tsukamurella paurometabola
DSM 20162]
gi|296028931|gb|ADG79701.1| hydroxymethylbutenyl pyrophosphate reductase [Tsukamurella paurometabola
DSM 20162]
Length=316
Score = 509 bits (1311), Expect = 2e-142, Method: Compositional matrix adjust.
Identities = 250/310 (81%), Positives = 280/310 (91%), Gaps = 1/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLAEPRGYCAGVDRAVETVE+AL+KHG PVYVR EIVHNRHVV+TL G +FV+ET
Sbjct 5 KRVLLAEPRGYCAGVDRAVETVEKALEKHGAPVYVRKEIVHNRHVVETLQDKGVIFVDET 64
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEG+++VFSAHGV+P VH A +R+L+ IDATCPLVTKVH EA+RFARDD+DILLIG
Sbjct 65 DEVPEGSLLVFSAHGVSPAVHAGAEQRSLRTIDATCPLVTKVHQEAKRFARDDFDILLIG 124
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAP+HVQLVDG DAVD V VRDE+K+VWLSQTTLSVDETME V RLR
Sbjct 125 HEGHEEVEGTAGEAPEHVQLVDGPDAVDAVQVRDEEKIVWLSQTTLSVDETMETVRRLRE 184
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FPKLQDPPSDDICYATQNRQVAVKAMAPEC+LVIVVGSRNSSNSVRLVEVAL AGARAA
Sbjct 185 KFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALQAGARAA 244
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HL+D+A +ID AWLDGV TVG+TSGASVPE+LV+GV+E L G+ V+PVTTANETLVF
Sbjct 245 HLIDFAREIDPAWLDGVQTVGITSGASVPEILVKGVVEYLDGEGFHDVKPVTTANETLVF 304
Query 326 ALPRELRSPR 335
ALPRELR PR
Sbjct 305 ALPRELR-PR 313
>gi|333989700|ref|YP_004522314.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Mycobacterium
sp. JDM601]
gi|333485668|gb|AEF35060.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Mycobacterium
sp. JDM601]
Length=309
Score = 509 bits (1310), Expect = 3e-142, Method: Compositional matrix adjust.
Identities = 253/308 (83%), Positives = 274/308 (89%), Gaps = 0/308 (0%)
Query 28 VLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQ 87
+LLAEPRGYCAGVDRAVETVERAL+KHG PVYVRHEIVHN+HVVDTL G VFV E ++
Sbjct 1 MLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEIVHNKHVVDTLTNKGVVFVHEADE 60
Query 88 VPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHE 147
VPEGA+VVFSAHGVAP+VH A++R L+VIDATCPLV KVHNEA+RFARD YDILLIGH
Sbjct 61 VPEGAMVVFSAHGVAPSVHDLAADRGLRVIDATCPLVNKVHNEAKRFARDGYDILLIGHA 120
Query 148 GHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRF 207
GHEEVVG GEAPD VQLVDG DAV V VRDE+KVVWLSQTTLSVDETM+ V +LR RF
Sbjct 121 GHEEVVGIIGEAPDDVQLVDGQDAVASVQVRDENKVVWLSQTTLSVDETMQTVVKLRERF 180
Query 208 PKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHL 267
PKLQDPPSDDICYATQNRQ AVKAMAP+CELVIVVGSRNSSNS RLVEVALGAGA AAHL
Sbjct 181 PKLQDPPSDDICYATQNRQTAVKAMAPQCELVIVVGSRNSSNSNRLVEVALGAGADAAHL 240
Query 268 VDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFAL 327
VD+ADDID +WLDGV +VGVTSGASVPE+LVRGVLERLA GY+ V PVTTANETLVFAL
Sbjct 241 VDYADDIDPSWLDGVESVGVTSGASVPEILVRGVLERLAGYGYETVYPVTTANETLVFAL 300
Query 328 PRELRSPR 335
PRE+R R
Sbjct 301 PREIRPDR 308
>gi|262201635|ref|YP_003272843.1| hydroxymethylbutenyl pyrophosphate reductase [Gordonia bronchialis
DSM 43247]
gi|262084982|gb|ACY20950.1| hydroxymethylbutenyl pyrophosphate reductase [Gordonia bronchialis
DSM 43247]
Length=317
Score = 502 bits (1292), Expect = 4e-140, Method: Compositional matrix adjust.
Identities = 249/310 (81%), Positives = 274/310 (89%), Gaps = 0/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLAEPRGYCAGVDRAVETVERAL KHG PVYVR EIVHNRHVV+TL+ GAVFV ET
Sbjct 5 KRVLLAEPRGYCAGVDRAVETVERALDKHGAPVYVRKEIVHNRHVVETLSDRGAVFVGET 64
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEGAIVVFSAHGV+P VH +A+ R+L+ IDATCPLVTKVH EA+RFARDDYDILLIG
Sbjct 65 DEVPEGAIVVFSAHGVSPEVHRTAAARSLKTIDATCPLVTKVHQEAKRFARDDYDILLIG 124
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAP+H+QLVDG D+VD+V+VRDE KV+WLSQTTLSVDETME V RLR
Sbjct 125 HEGHEEVEGTAGEAPEHIQLVDGPDSVDKVSVRDESKVIWLSQTTLSVDETMETVKRLRE 184
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP+L DPPSDDICYATQNRQVAVKAMAP C+LVIVVGS NSSNSVRLVEVA+ GA A
Sbjct 185 KFPQLADPPSDDICYATQNRQVAVKAMAPHCDLVIVVGSTNSSNSVRLVEVAVQNGASAG 244
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+A +ID AWL+GV TVGVTSGASVPEVLVRGVL+ LAE GYD V+ V TA ETL F
Sbjct 245 HLVDYAREIDPAWLEGVNTVGVTSGASVPEVLVRGVLDYLAERGYDSVETVNTAEETLTF 304
Query 326 ALPRELRSPR 335
ALPRELR R
Sbjct 305 ALPRELRPAR 314
>gi|343925120|ref|ZP_08764652.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Gordonia
alkanivorans NBRC 16433]
gi|343765051|dbj|GAA11578.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Gordonia
alkanivorans NBRC 16433]
Length=295
Score = 478 bits (1230), Expect = 6e-133, Method: Compositional matrix adjust.
Identities = 237/292 (82%), Positives = 258/292 (89%), Gaps = 0/292 (0%)
Query 44 VETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAP 103
+ETVERAL KHG PVYVR EIVHNRHVV+TLA GA+FV ET++VPEGAIVVFSAHGV+P
Sbjct 1 METVERALDKHGAPVYVRKEIVHNRHVVETLADRGAIFVGETDEVPEGAIVVFSAHGVSP 60
Query 104 TVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHV 163
VH SA+ERNL+ IDATCPLVTKVH EA+RFARDDYDILLIGHEGHEEV GTAGEAP H+
Sbjct 61 QVHASAAERNLRTIDATCPLVTKVHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPQHI 120
Query 164 QLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQ 223
QLVDG D+VD VTVRDE K+VWLSQTTLSVDETME V RLR +FP L DPPSDDICYATQ
Sbjct 121 QLVDGPDSVDSVTVRDESKLVWLSQTTLSVDETMETVRRLREKFPLLNDPPSDDICYATQ 180
Query 224 NRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVT 283
NRQVAVKAMAPEC+LVIVVGS+NSSNSVRLVEVAL AGA+A HLVD+A +ID WL+GV
Sbjct 181 NRQVAVKAMAPECDLVIVVGSQNSSNSVRLVEVALQAGAKAGHLVDYAREIDDTWLEGVN 240
Query 284 TVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
TVGVTSGASVPEVLVRGVL+ LAE GYD V+ V TANETL FALPRELR R
Sbjct 241 TVGVTSGASVPEVLVRGVLDYLAERGYDTVETVNTANETLTFALPRELRPAR 292
>gi|257057116|ref|YP_003134948.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Saccharomonospora
viridis DSM 43017]
gi|256586988|gb|ACU98121.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Saccharomonospora
viridis DSM 43017]
Length=327
Score = 472 bits (1215), Expect = 3e-131, Method: Compositional matrix adjust.
Identities = 231/309 (75%), Positives = 267/309 (87%), Gaps = 0/309 (0%)
Query 24 NRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVE 83
N KRVLLA+PRGYCAGVDRAV TVE+AL+K+GPP+YVR EIVHN++VVDTL K G +FV+
Sbjct 9 NGKRVLLAKPRGYCAGVDRAVVTVEKALEKYGPPIYVRKEIVHNKYVVDTLRKRGVIFVD 68
Query 84 ETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILL 143
ET +VPEG++VVFSAHGV+P VH A+ERNL+ IDATCPLVTKVH E RFARDDYDILL
Sbjct 69 ETSEVPEGSLVVFSAHGVSPAVHAEAAERNLRTIDATCPLVTKVHREVVRFARDDYDILL 128
Query 144 IGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRL 203
IGHEGHEEV GTAGEAPD VQLVD + V +VTVRD KVVW+SQTTLSVDETME V +L
Sbjct 129 IGHEGHEEVEGTAGEAPDRVQLVDTPEDVHKVTVRDPSKVVWVSQTTLSVDETMERVNQL 188
Query 204 RRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGAR 263
+ RFP+L DPPS+DICYAT NRQ AVKAMAPEC+LV+VVGS+NSSNS RLVEVAL AGAR
Sbjct 189 KERFPELADPPSEDICYATSNRQTAVKAMAPECDLVLVVGSQNSSNSKRLVEVALQAGAR 248
Query 264 AAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETL 323
AHL+D+A ++D WL+GV T+GVTSGASVP+VLV +LE+LAE G+D VQ VTTANE +
Sbjct 249 DAHLIDYAHEVDEKWLEGVETIGVTSGASVPDVLVMELLEKLAERGWDDVQEVTTANEKI 308
Query 324 VFALPRELR 332
FALPRELR
Sbjct 309 TFALPRELR 317
>gi|302530082|ref|ZP_07282424.1| LytB protein [Streptomyces sp. AA4]
gi|302438977|gb|EFL10793.1| LytB protein [Streptomyces sp. AA4]
Length=336
Score = 470 bits (1210), Expect = 1e-130, Method: Compositional matrix adjust.
Identities = 231/307 (76%), Positives = 263/307 (86%), Gaps = 0/307 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLA+PRGYCAGVDRAV VE+AL+ +GPPVYVR EIVHNRHVVDTL + G +FV+ET
Sbjct 23 KRVLLAKPRGYCAGVDRAVVAVEKALELYGPPVYVRKEIVHNRHVVDTLRERGVIFVDET 82
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
+VPEGA+VVFSAHGV+P VH A+ERNL+ IDATCPLVTKVH E RFA+DDYDILLIG
Sbjct 83 SEVPEGALVVFSAHGVSPAVHAEAAERNLRTIDATCPLVTKVHKEVNRFAKDDYDILLIG 142
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAPD VQLVD + VD+V VRD KV+WLSQTTLSVDETME V +LR
Sbjct 143 HEGHEEVEGTAGEAPDKVQLVDKPEDVDKVDVRDPSKVIWLSQTTLSVDETMERVDQLRD 202
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
RFP L DPPSDDICYAT NRQVAVKAMAPEC+LV+VVGS+NSSNS RLVEVAL AGA A+
Sbjct 203 RFPTLSDPPSDDICYATTNRQVAVKAMAPECDLVLVVGSKNSSNSKRLVEVALKAGASAS 262
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HL+D+A ++D AWL+GV+TVGVTSGASVP+VLV +L+ LAE GY V VTTANE + F
Sbjct 263 HLIDFASEVDEAWLEGVSTVGVTSGASVPDVLVMDLLKWLAERGYGQVDEVTTANEKIAF 322
Query 326 ALPRELR 332
ALP+ELR
Sbjct 323 ALPKELR 329
>gi|317125806|ref|YP_004099918.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Intrasporangium
calvum DSM 43043]
gi|315589894|gb|ADU49191.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Intrasporangium
calvum DSM 43043]
Length=339
Score = 469 bits (1208), Expect = 2e-130, Method: Compositional matrix adjust.
Identities = 232/306 (76%), Positives = 263/306 (86%), Gaps = 0/306 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
K+VLLA PRGYCAGVDRAV TVE+AL+ +GPPVYVR +IVHN+HVV TL + GA+FV+ET
Sbjct 6 KKVLLAAPRGYCAGVDRAVVTVEKALELYGPPVYVRKQIVHNKHVVSTLERRGAIFVDET 65
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
E+VPEGA V+FSAHGVAP VH A R+L+ IDATCPLVTKVH EA RFA DDYDILLIG
Sbjct 66 EEVPEGATVIFSAHGVAPVVHEEARTRSLKTIDATCPLVTKVHREAVRFASDDYDILLIG 125
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV+GT+GEAP+H+ +VDG VD VTVRD +KVVWLSQTTLSVDETME V RLR
Sbjct 126 HEGHEEVIGTSGEAPEHITIVDGPADVDNVTVRDPEKVVWLSQTTLSVDETMETVKRLRE 185
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP LQ+PPSDDICYATQNRQ+AVK MAP+ +L+IVVGSRNSSNSVRLVEVAL GARA
Sbjct 186 KFPALQNPPSDDICYATQNRQLAVKQMAPDTDLMIVVGSRNSSNSVRLVEVALEHGARAG 245
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+AD+ID AWL+GVTTVGVTSGASVPEVLVR VL LAE GY V+PV A E+L+F
Sbjct 246 HLVDFADEIDEAWLEGVTTVGVTSGASVPEVLVRDVLSWLAERGYATVEPVVAAEESLLF 305
Query 326 ALPREL 331
ALP EL
Sbjct 306 ALPHEL 311
>gi|256374878|ref|YP_003098538.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Actinosynnema
mirum DSM 43827]
gi|255919181|gb|ACU34692.1| hydroxymethylbutenyl pyrophosphate reductase [Actinosynnema mirum
DSM 43827]
Length=314
Score = 468 bits (1205), Expect = 5e-130, Method: Compositional matrix adjust.
Identities = 225/308 (74%), Positives = 269/308 (88%), Gaps = 0/308 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLA PRGYCAGVDRAV TVE+AL+K+G PVYVR EIVHN+HVV+TL+K GA+FV ET
Sbjct 3 KRVLLANPRGYCAGVDRAVVTVEKALEKYGAPVYVRKEIVHNKHVVETLSKRGAIFVNET 62
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEGA+VVFSAHGV+P VH A++R+L+ IDATCPLVTKVH EA+RFAR+DYDILLIG
Sbjct 63 DEVPEGALVVFSAHGVSPKVHEEAADRSLRTIDATCPLVTKVHKEAQRFAREDYDILLIG 122
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV GTAGEAPDH+QLVD + V +V VRD KV+WLSQTTLSVDETM V +L+
Sbjct 123 HEGHEEVEGTAGEAPDHIQLVDTAEDVAKVEVRDPSKVIWLSQTTLSVDETMVRVRQLKE 182
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
RFP LQ+PPSDDICYAT NRQVAVK MAPEC+LV+VVGS+NSSNSVRLVEVAL AGA+A+
Sbjct 183 RFPDLQEPPSDDICYATSNRQVAVKTMAPECDLVLVVGSKNSSNSVRLVEVALQAGAKAS 242
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
+L+D+A+++D AWL+GV TVGVTSGASVP++LV +L+ LAE GY V+ +TTANE + F
Sbjct 243 YLIDYAEEVDEAWLEGVGTVGVTSGASVPDILVMDLLKHLAERGYGDVEEITTANEKIAF 302
Query 326 ALPRELRS 333
+LPRELR
Sbjct 303 SLPRELRK 310
>gi|324997965|ref|ZP_08119077.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Pseudonocardia
sp. P1]
Length=320
Score = 468 bits (1203), Expect = 8e-130, Method: Compositional matrix adjust.
Identities = 229/310 (74%), Positives = 265/310 (86%), Gaps = 0/310 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
K+VLLA+PRGYCAGVDRAVE VE+AL ++G PVYVR EIVHN+HVV+TL GA+FVEE
Sbjct 6 KQVLLAKPRGYCAGVDRAVEAVEQALDQYGAPVYVRKEIVHNKHVVETLRDRGAIFVEEA 65
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
+VPEGA VVFSAHGV+P V A R L+ IDATCPLVTKVH EA+RFAR+DYDILL+G
Sbjct 66 SEVPEGAHVVFSAHGVSPAVRDEAKGRELRTIDATCPLVTKVHQEAKRFAREDYDILLVG 125
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
H GHEEV GT+GEAP+H+QLV+ VD+VTVRD DKVVWLSQTTLSVDETME V LR
Sbjct 126 HAGHEEVEGTSGEAPEHIQLVESAADVDKVTVRDPDKVVWLSQTTLSVDETMETVRALRE 185
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FPKLQ+PPSDDICYATQNRQVAVK MAP C+LV+VVGSRNSSNSVRLVEVALGAGA ++
Sbjct 186 KFPKLQNPPSDDICYATQNRQVAVKTMAPRCDLVLVVGSRNSSNSVRLVEVALGAGAGSS 245
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
+L+D+A +ID WL+GV T+GVTSGASVPEVLVRGV++ LAE G+ V+ V TA ETLVF
Sbjct 246 YLIDYAKEIDETWLEGVQTIGVTSGASVPEVLVRGVVDHLAERGFGSVEEVDTAEETLVF 305
Query 326 ALPRELRSPR 335
+LPRELR PR
Sbjct 306 SLPRELRPPR 315
>gi|84494714|ref|ZP_00993833.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Janibacter
sp. HTCC2649]
gi|84384207|gb|EAQ00087.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Janibacter
sp. HTCC2649]
Length=341
Score = 468 bits (1203), Expect = 9e-130, Method: Compositional matrix adjust.
Identities = 230/307 (75%), Positives = 265/307 (87%), Gaps = 0/307 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLA PRGYCAGVDRAV TVE+AL +G PVYVR EIVHN+HVV TL K GA+FVEET
Sbjct 10 KRVLLAAPRGYCAGVDRAVVTVEKALDLYGAPVYVRKEIVHNKHVVTTLEKRGAIFVEET 69
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEG+ V+FSAHGVAP VH A L+ IDATCPLVTKVH EA RFA DD+DILLIG
Sbjct 70 DEVPEGSTVIFSAHGVAPVVHEEAKALGLKTIDATCPLVTKVHREAVRFASDDFDILLIG 129
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEVVGTAGEAP+H+ LV+G D+VD V VRD DKVVWLSQTTLSVDETME V RLR+
Sbjct 130 HEGHEEVVGTAGEAPEHITLVEGPDSVDGVEVRDPDKVVWLSQTTLSVDETMETVRRLRQ 189
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP +QDPPSDDICYATQNRQ+AVK MAP+C+L+IVVGSRNSSNSVRLVEVAL G++A
Sbjct 190 KFPLMQDPPSDDICYATQNRQLAVKHMAPDCDLMIVVGSRNSSNSVRLVEVALEHGSKAG 249
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
+LVD+AD+I+ +WLDGV TVGVTSGASVPE+LVRGVL+ LAE GY+ V+PV A E+LVF
Sbjct 250 YLVDYADEIEESWLDGVGTVGVTSGASVPELLVRGVLDYLAERGYEDVRPVRAAEESLVF 309
Query 326 ALPRELR 332
+LP E+R
Sbjct 310 SLPNEIR 316
>gi|326381855|ref|ZP_08203548.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Gordonia
neofelifaecis NRRL B-59395]
gi|326199281|gb|EGD56462.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Gordonia
neofelifaecis NRRL B-59395]
Length=295
Score = 466 bits (1199), Expect = 2e-129, Method: Compositional matrix adjust.
Identities = 231/292 (80%), Positives = 257/292 (89%), Gaps = 0/292 (0%)
Query 44 VETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAP 103
+ETVER L KHG PVYVR EIVHNRHVVDTL + GA+FV+ET++VPEGAIVVFSAHGV+P
Sbjct 1 METVERTLDKHGAPVYVRKEIVHNRHVVDTLTERGAIFVDETDEVPEGAIVVFSAHGVSP 60
Query 104 TVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHV 163
VH +A+ER+L+ IDATCPLVTKVH EA+RFARDDYDI+LIGHEGHEEV GTAGEAP+H+
Sbjct 61 EVHKTAAERSLKTIDATCPLVTKVHQEAKRFARDDYDIVLIGHEGHEEVEGTAGEAPEHI 120
Query 164 QLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQ 223
Q+VDG DAVD V VRDE +V+WLSQTTLSVDETME V RLR RFP L DPPSDDICYATQ
Sbjct 121 QVVDGPDAVDDVQVRDESRVIWLSQTTLSVDETMETVSRLRERFPDLNDPPSDDICYATQ 180
Query 224 NRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVT 283
NRQVAVKAMAP+CELVIVVGS+NSSNS RLVEVAL GA A++LVD+A DID AWLDGV+
Sbjct 181 NRQVAVKAMAPQCELVIVVGSQNSSNSQRLVEVALQNGAEASYLVDYARDIDLAWLDGVS 240
Query 284 TVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR 335
TVGVTSGASVPEVLVRGV++ LAE GY VQ VTTA ETL FALPRELR R
Sbjct 241 TVGVTSGASVPEVLVRGVVDLLAEHGYGDVQTVTTAEETLTFALPRELRPAR 292
>gi|291451500|ref|ZP_06590890.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
albus J1074]
gi|291354449|gb|EFE81351.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
albus J1074]
Length=332
Score = 466 bits (1199), Expect = 2e-129, Method: Compositional matrix adjust.
Identities = 225/310 (73%), Positives = 265/310 (86%), Gaps = 0/310 (0%)
Query 23 PNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFV 82
P KRVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL + GA+FV
Sbjct 9 PTAKRVLLAAPRGYCAGVDRAVIAVEKALEQYGSPIYVRHEIVHNKYVVQTLERKGAIFV 68
Query 83 EETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDIL 142
EET +VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA RFA+DDYDIL
Sbjct 69 EETAEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRFAQDDYDIL 128
Query 143 LIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGR 202
LIGHEGHEEV+GT+GEAPDH+ LVDG + V+ V VRD+ KVVWLSQTTLSVDETME V R
Sbjct 129 LIGHEGHEEVIGTSGEAPDHITLVDGPEDVENVEVRDDSKVVWLSQTTLSVDETMETVDR 188
Query 203 LRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGA 262
L+ +FP+L PPSDDICYATQNRQ+AVK M + +LVIVVGS+NSSNSVRLVEVALGAGA
Sbjct 189 LKEKFPQLISPPSDDICYATQNRQIAVKQMGGQADLVIVVGSKNSSNSVRLVEVALGAGA 248
Query 263 RAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANET 322
R AHLVD+A++ID AWL+GV TVGVTSGASVP+VLV GVLE L+ G++ V+ V A E+
Sbjct 249 RDAHLVDFAEEIDEAWLEGVGTVGVTSGASVPDVLVEGVLEWLSTRGFEDVELVKAAEES 308
Query 323 LVFALPRELR 332
+ F+LP+ELR
Sbjct 309 ITFSLPKELR 318
>gi|345001825|ref|YP_004804679.1| hydroxymethylbutenyl pyrophosphate reductase [Streptomyces sp.
SirexAA-E]
gi|344317451|gb|AEN12139.1| hydroxymethylbutenyl pyrophosphate reductase [Streptomyces sp.
SirexAA-E]
Length=329
Score = 466 bits (1198), Expect = 3e-129, Method: Compositional matrix adjust.
Identities = 223/307 (73%), Positives = 266/307 (87%), Gaps = 0/307 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
+RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL K GA+FVE+T
Sbjct 10 RRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIFVEQT 69
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
+VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA R+A++DYDILLIG
Sbjct 70 AEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKEDYDILLIG 129
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
H+GHEEV+GT+GEAPDH+ LVDG + V V VRDE KVVWLSQTTLSVDETME VG L++
Sbjct 130 HDGHEEVIGTSGEAPDHITLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVGALKQ 189
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP L PPSDDICYATQNRQ+AVK ++ E ELVIVVGS+NSSNS+R+VEVAL AGA AA
Sbjct 190 KFPNLLSPPSDDICYATQNRQIAVKKLSEEAELVIVVGSKNSSNSIRMVEVALDAGAPAA 249
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+AD+ID AWL+GVTTVG+TSGASVP+VLV GV+E LAE GY V+ V TA+E++ F
Sbjct 250 HLVDFADEIDEAWLEGVTTVGLTSGASVPDVLVDGVIEWLAERGYADVETVKTADESITF 309
Query 326 ALPRELR 332
+LP+ELR
Sbjct 310 SLPKELR 316
>gi|291447427|ref|ZP_06586817.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
roseosporus NRRL 15998]
gi|291350374|gb|EFE77278.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
roseosporus NRRL 15998]
Length=343
Score = 466 bits (1198), Expect = 3e-129, Method: Compositional matrix adjust.
Identities = 224/311 (73%), Positives = 266/311 (86%), Gaps = 0/311 (0%)
Query 22 RPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVF 81
R N +RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL K GA+F
Sbjct 20 RSNTRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIF 79
Query 82 VEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDI 141
V+ T +VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA R+A++DYDI
Sbjct 80 VDVTAEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKEDYDI 139
Query 142 LLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVG 201
LLIGHEGHEEV+GT+GEAPDH+QLVDG + V V VRDE KVVWLSQTTLSVDETME V
Sbjct 140 LLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVD 199
Query 202 RLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAG 261
L+ +FP L PPSDDICYATQNRQ+AVK +A + ELVIVVGS+NSSNS+R+VEVAL AG
Sbjct 200 ALKSKFPNLLSPPSDDICYATQNRQIAVKKLAEDAELVIVVGSKNSSNSIRMVEVALDAG 259
Query 262 ARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANE 321
A AAHLVD+A +ID AWL+GVTTVG+TSGASVP+VLV GV+E LAE GY+ V+ V TA+E
Sbjct 260 APAAHLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVIEWLAERGYEDVETVKTADE 319
Query 322 TLVFALPRELR 332
++ F+LP+ELR
Sbjct 320 SITFSLPKELR 330
>gi|331694831|ref|YP_004331070.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Pseudonocardia
dioxanivorans CB1190]
gi|326949520|gb|AEA23217.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Pseudonocardia
dioxanivorans CB1190]
Length=319
Score = 465 bits (1197), Expect = 4e-129, Method: Compositional matrix adjust.
Identities = 229/314 (73%), Positives = 263/314 (84%), Gaps = 0/314 (0%)
Query 22 RPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVF 81
R KR+LLA+PRGYCAGVDRAVE VE+AL++HG PVYVR +IVHN HVV+TL + GA+F
Sbjct 3 RAETKRILLAKPRGYCAGVDRAVEAVEKALEQHGAPVYVRKQIVHNVHVVETLTERGAIF 62
Query 82 VEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDI 141
V+ET++VP G+IVVFSAHGV+P V A +R L+ IDATCPLVTKVH E +RFAR+DYDI
Sbjct 63 VDETDEVPPGSIVVFSAHGVSPAVRQQAEDRELRTIDATCPLVTKVHGEVKRFAREDYDI 122
Query 142 LLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVG 201
LL+GH GHEEV GT+GEAP +VQLVD V VTVRD DKVVWLSQTTLSVDETME V
Sbjct 123 LLVGHRGHEEVEGTSGEAPGNVQLVDSAADVASVTVRDPDKVVWLSQTTLSVDETMETVA 182
Query 202 RLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAG 261
LR RFP LQ+PPSDDICYATQNRQ+AVKAMAP C+LV+VVGS NSSNSVRLVEVAL AG
Sbjct 183 ALRERFPTLQNPPSDDICYATQNRQIAVKAMAPHCDLVLVVGSANSSNSVRLVEVALAAG 242
Query 262 ARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANE 321
A A++L+D+A ID +WL+GVTTVGVTSGASVPEVLVRGVLE L E G+ V+ +TTA E
Sbjct 243 AGASYLIDYARQIDESWLEGVTTVGVTSGASVPEVLVRGVLEHLGEHGFGEVEEITTAEE 302
Query 322 TLVFALPRELRSPR 335
TL FALPRELR R
Sbjct 303 TLTFALPRELRPSR 316
>gi|317506622|ref|ZP_07964413.1| LytB protein [Segniliparus rugosus ATCC BAA-974]
gi|316255054|gb|EFV14333.1| LytB protein [Segniliparus rugosus ATCC BAA-974]
Length=309
Score = 465 bits (1197), Expect = 4e-129, Method: Compositional matrix adjust.
Identities = 228/308 (75%), Positives = 266/308 (87%), Gaps = 0/308 (0%)
Query 28 VLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQ 87
+ LA PRGYCAGVDRAV+ VE AL HG PVYVR EIVHNRHVV+TLA+ G VFV E ++
Sbjct 1 MYLASPRGYCAGVDRAVQAVEEALALHGAPVYVRKEIVHNRHVVETLAERGVVFVGEADE 60
Query 88 VPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHE 147
VPEGA+++FSAHG++P V A++R L+ IDATCPLVTKVH E +RFARDD DILLIGHE
Sbjct 61 VPEGALLIFSAHGISPAVRDLAAQRGLRTIDATCPLVTKVHQEVKRFARDDCDILLIGHE 120
Query 148 GHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRF 207
GHEEV GTAGEAP+HVQLVD V AVDQ+ VR+ K+VW+SQTTLSVDETMEIV +LR RF
Sbjct 121 GHEEVEGTAGEAPEHVQLVDSVKAVDQIQVREGVKLVWVSQTTLSVDETMEIVTKLRERF 180
Query 208 PKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHL 267
P+LQDPPSDDICYATQNRQVAVKAMAP+C+LVIVVGSRNSSNSVRLVEVALGAGA+AA+L
Sbjct 181 PQLQDPPSDDICYATQNRQVAVKAMAPDCDLVIVVGSRNSSNSVRLVEVALGAGAKAAYL 240
Query 268 VDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFAL 327
VD+A DID AWLDGV +VG++SGASVPE+LV+GVLE LA+ G+ VQ V TA ET+VF+L
Sbjct 241 VDYAKDIDPAWLDGVRSVGISSGASVPEILVQGVLEMLAQHGFADVQQVVTAQETVVFSL 300
Query 328 PRELRSPR 335
P +R+ R
Sbjct 301 PTGVRASR 308
>gi|320008796|gb|ADW03646.1| hydroxymethylbutenyl pyrophosphate reductase [Streptomyces flavogriseus
ATCC 33331]
Length=346
Score = 463 bits (1192), Expect = 1e-128, Method: Compositional matrix adjust.
Identities = 228/318 (72%), Positives = 267/318 (84%), Gaps = 4/318 (1%)
Query 15 SSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTL 74
+SRS DR RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL
Sbjct 20 ASRSSGDR----RVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTL 75
Query 75 AKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRF 134
K GA+FV+ T +VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA R+
Sbjct 76 EKKGAIFVDVTAEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRY 135
Query 135 ARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVD 194
A++DYDILLIGHEGHEEV+GT+GEAPDH+ LVDG D V V VRDE KVVWLSQTTLSVD
Sbjct 136 AKEDYDILLIGHEGHEEVIGTSGEAPDHITLVDGPDDVANVEVRDESKVVWLSQTTLSVD 195
Query 195 ETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLV 254
ETME VG L+ +FP L PPSDDICYATQNRQVAVK +A + +LVIVVGS+NSSNS+R+V
Sbjct 196 ETMETVGALKNKFPNLLSPPSDDICYATQNRQVAVKKLAEDADLVIVVGSKNSSNSIRMV 255
Query 255 EVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQ 314
EVAL AGA AAHLVD+A +ID AWL+GVTTVG+TSGASVP+VLV GVLE L E GY V+
Sbjct 256 EVALDAGAPAAHLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVE 315
Query 315 PVTTANETLVFALPRELR 332
V TA+E++ F+LP+ELR
Sbjct 316 TVKTADESITFSLPKELR 333
>gi|326776894|ref|ZP_08236159.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
cf. griseus XylebKG-1]
gi|326657227|gb|EGE42073.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
griseus XylebKG-1]
Length=329
Score = 462 bits (1190), Expect = 3e-128, Method: Compositional matrix adjust.
Identities = 224/307 (73%), Positives = 262/307 (86%), Gaps = 0/307 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
+RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL K GA+FV+ T
Sbjct 10 RRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIFVDVT 69
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
+VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA R+A+DDYDILLIG
Sbjct 70 AEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKDDYDILLIG 129
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV+GT+GEAPDH+QLVDG + V V VRDE KVVWLSQTTLSVDETME V L+
Sbjct 130 HEGHEEVIGTSGEAPDHIQLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVDALKS 189
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP L PPSDDICYATQNRQ+AVK +A + ELVIVVGS+NSSNS+R+VEVAL AGA AA
Sbjct 190 KFPNLLSPPSDDICYATQNRQIAVKKLAEDAELVIVVGSKNSSNSIRMVEVALDAGAPAA 249
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+A +ID AWLDGVTTVG+TSGASVP+VLV GVLE L E GY V+ V TA+E++ F
Sbjct 250 HLVDFASEIDEAWLDGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVETVKTADESITF 309
Query 326 ALPRELR 332
+LP+ELR
Sbjct 310 SLPKELR 316
>gi|334336435|ref|YP_004541587.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Isoptericola
variabilis 225]
gi|334106803|gb|AEG43693.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Isoptericola
variabilis 225]
Length=346
Score = 462 bits (1189), Expect = 3e-128, Method: Compositional matrix adjust.
Identities = 232/308 (76%), Positives = 263/308 (86%), Gaps = 0/308 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
KRVLLA PRGYCAGVDRAV VE+AL+ +G PVYVR EIVHN+HVV TL + GA+FV ET
Sbjct 14 KRVLLAAPRGYCAGVDRAVVAVEKALETYGAPVYVRKEIVHNKHVVATLRERGAIFVNET 73
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
++VPEGA +VFSAHGV+P V SA+ER+L IDATCPLVTKVH EA RFA+DDYDILLIG
Sbjct 74 DEVPEGARLVFSAHGVSPAVRASAAERSLDTIDATCPLVTKVHKEAVRFAKDDYDILLIG 133
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
H+GHEEV GTAGEAPDHVQ+V+ D VD+VTVRD DKVVW+SQTTLSVDETME V RLR
Sbjct 134 HDGHEEVEGTAGEAPDHVQVVNSPDEVDKVTVRDPDKVVWISQTTLSVDETMETVRRLRE 193
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
RFP LQDPPSDDICYATQNRQVAVK +APEC+LVIVVGS NSSNSVRLVEVAL AGAR+A
Sbjct 194 RFPSLQDPPSDDICYATQNRQVAVKKLAPECDLVIVVGSANSSNSVRLVEVALEAGARSA 253
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
+ VD A +I+ WLDGVTTVGVTSGASVPE+LV+ V+ LAE GY V+ V TA E L+F
Sbjct 254 YRVDRATEIEEEWLDGVTTVGVTSGASVPEILVQDVIRHLAERGYGDVEEVRTATEDLMF 313
Query 326 ALPRELRS 333
+LPRELR+
Sbjct 314 SLPRELRA 321
>gi|182436265|ref|YP_001823984.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
griseus subsp. griseus NBRC 13350]
gi|238689020|sp|B1W2D7.1|ISPH_STRGG RecName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase
gi|178464781|dbj|BAG19301.1| putative 4-hydroxy-3-methylbut-2-enyl diphosphate [Streptomyces
griseus subsp. griseus NBRC 13350]
Length=329
Score = 461 bits (1185), Expect = 9e-128, Method: Compositional matrix adjust.
Identities = 223/307 (73%), Positives = 262/307 (86%), Gaps = 0/307 (0%)
Query 26 KRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEET 85
+RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL K GA+FV+ T
Sbjct 10 RRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIFVDVT 69
Query 86 EQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIG 145
+VPEG+IV+FSAHGVAPTVH A+ER L IDATCPLVTKVH EA R+A+DDYDILLIG
Sbjct 70 AEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKDDYDILLIG 129
Query 146 HEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRR 205
HEGHEEV+GT+GEAPDH+QLVDG + V V VRDE KVVWLSQTTLSVDETME V L+
Sbjct 130 HEGHEEVIGTSGEAPDHIQLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVDALKS 189
Query 206 RFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAA 265
+FP L PPSDDICYATQNRQ+AVK +A + ELVIVVGS+NSSNS+R+VEVAL AGA AA
Sbjct 190 KFPNLLSPPSDDICYATQNRQIAVKKLAEDAELVIVVGSKNSSNSIRMVEVALDAGAPAA 249
Query 266 HLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVF 325
HLVD+A +ID AWL+GVTTVG+TSGASVP+VLV GVLE L E GY V+ V TA+E++ F
Sbjct 250 HLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVETVKTADESITF 309
Query 326 ALPRELR 332
+LP+ELR
Sbjct 310 SLPKELR 316
>gi|297192334|ref|ZP_06909732.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
pristinaespiralis ATCC 25486]
gi|297151299|gb|EFH31071.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
pristinaespiralis ATCC 25486]
Length=338
Score = 461 bits (1185), Expect = 9e-128, Method: Compositional matrix adjust.
Identities = 224/310 (73%), Positives = 264/310 (86%), Gaps = 0/310 (0%)
Query 23 PNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFV 82
P +RVLLA PRGYCAGVDRAV VE+AL+++G P+YVRHEIVHN++VV TL K GA+FV
Sbjct 12 PPARRVLLAAPRGYCAGVDRAVIAVEKALEQYGSPIYVRHEIVHNKYVVQTLEKKGAIFV 71
Query 83 EETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDIL 142
+ET +VPEG+IV+FSAHGVAPTVH A++R L IDATCPLVTKVH EA RFA++DYDIL
Sbjct 72 DETAEVPEGSIVMFSAHGVAPTVHEEAAQRKLATIDATCPLVTKVHKEAVRFAQEDYDIL 131
Query 143 LIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGR 202
LIGHEGHEEV+GT+GEAPDH+ LVDG + V V VR+ DKVVWLSQTTLSVDETME V
Sbjct 132 LIGHEGHEEVIGTSGEAPDHITLVDGPEDVANVEVRNPDKVVWLSQTTLSVDETMETVDA 191
Query 203 LRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGA 262
L+ +FP L PPSDDICYATQNRQ+AVK M E +LVIVVGS+NSSNSVRLVEVALGAGA
Sbjct 192 LKTKFPGLISPPSDDICYATQNRQIAVKQMGAEADLVIVVGSKNSSNSVRLVEVALGAGA 251
Query 263 RAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANET 322
R AHLVD+AD+I+ AWLDGV+TVGVTSGASVPEVLV GVLE L++ G++ V+ V A E+
Sbjct 252 RDAHLVDFADEIEEAWLDGVSTVGVTSGASVPEVLVEGVLEWLSKRGFEDVEIVKAAEES 311
Query 323 LVFALPRELR 332
+ F+LP+ELR
Sbjct 312 ITFSLPKELR 321
>gi|294814789|ref|ZP_06773432.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
clavuligerus ATCC 27064]
gi|294327388|gb|EFG09031.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Streptomyces
clavuligerus ATCC 27064]
Length=346
Score = 461 bits (1185), Expect = 1e-127, Method: Compositional matrix adjust.
Identities = 223/310 (72%), Positives = 262/310 (85%), Gaps = 0/310 (0%)
Query 23 PNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFV 82
P +RVLLA PRGYCAGVDRAV VE+AL+++G PVYVRHEIVHN++VV TL + GAVFV
Sbjct 5 PAARRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPVYVRHEIVHNKYVVQTLERKGAVFV 64
Query 83 EETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDIL 142
++T +VPEG+IV+FSAHGVAP VH A+ R L IDATCPLVTKVH EA RFA +DYDIL
Sbjct 65 DKTAEVPEGSIVMFSAHGVAPVVHEEAARRKLATIDATCPLVTKVHKEAVRFANEDYDIL 124
Query 143 LIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGR 202
LIGHEGHEEV+GT+GEAPDH+ LVDG D VD+V VRDE KVVWLSQTTLSVDETME V R
Sbjct 125 LIGHEGHEEVIGTSGEAPDHITLVDGPDDVDKVEVRDESKVVWLSQTTLSVDETMETVDR 184
Query 203 LRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGA 262
L+ +FP+L PPSDDICYATQNRQ AVK M + +LVIVVGS+NSSNSVRLVEVALGAGA
Sbjct 185 LKEKFPQLISPPSDDICYATQNRQTAVKQMGADADLVIVVGSKNSSNSVRLVEVALGAGA 244
Query 263 RAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANET 322
R AHLVD+A++ID AWL+GV TVG+TSGASVPE+LV GVLE L++ G+ V+ V A E+
Sbjct 245 RDAHLVDFAEEIDEAWLEGVATVGLTSGASVPEILVEGVLEWLSQRGFQDVELVKAAEES 304
Query 323 LVFALPRELR 332
+ F+LP+ELR
Sbjct 305 ITFSLPKELR 314
Lambda K H
0.318 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 602106349260
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40