BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1119c

Length=49
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15840557|ref|NP_335594.1|  hypothetical protein MT1151 [Mycoba...   100    1e-19
gi|15608259|ref|NP_215635.1|  hypothetical protein Rv1119c [Mycob...   100    1e-19
gi|118616046|ref|YP_904378.1|  hypothetical protein MUL_0150 [Myc...  63.5    1e-08
gi|183984311|ref|YP_001852602.1|  hypothetical protein MMAR_4340 ...  60.5    8e-08
gi|240171082|ref|ZP_04749741.1|  adenylate and guanylate cyclase ...  50.8    6e-05
gi|296169989|ref|ZP_06851595.1|  adenylate/guanylate cyclase [Myc...  49.7    1e-04
gi|254819690|ref|ZP_05224691.1|  adenylate and guanylate cyclase ...  42.0    0.034
gi|336458740|gb|EGO37700.1|  family 3 adenylate cyclase [Mycobact...  40.4    0.087
gi|41408770|ref|NP_961606.1|  hypothetical protein MAP2672 [Mycob...  40.4    0.097
gi|118464216|ref|YP_880496.1|  adenylate and guanylate cyclase ca...  38.5    0.35 
gi|254774128|ref|ZP_05215644.1|  adenylate and guanylate cyclase ...  38.5    0.36 
gi|54124769|gb|AAV30108.1|  Cya1120 [Mycobacterium avium]             38.1    0.44 
gi|126434113|ref|YP_001069804.1|  putative adenylate/guanylate cy...  37.4    0.68 
gi|342861708|ref|ZP_08718354.1|  adenylate and guanylate cyclase ...  36.6    1.4  
gi|108798513|ref|YP_638710.1|  adenylate/guanylate cyclase [Mycob...  36.6    1.4  
gi|333922094|ref|YP_004495675.1|  adenylate and guanylate cyclase...  33.9    9.4  


>gi|15840557|ref|NP_335594.1| hypothetical protein MT1151 [Mycobacterium tuberculosis CDC1551]
 gi|253799840|ref|YP_003032841.1| hypothetical protein TBMG_02863 [Mycobacterium tuberculosis KZN 
1435]
 gi|298524617|ref|ZP_07012026.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|13880735|gb|AAK45408.1| hypothetical protein MT1151 [Mycobacterium tuberculosis CDC1551]
 gi|253321343|gb|ACT25946.1| hypothetical protein TBMG_02863 [Mycobacterium tuberculosis KZN 
1435]
 gi|298494411|gb|EFI29705.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|323720401|gb|EGB29495.1| hypothetical protein TMMG_01811 [Mycobacterium tuberculosis CDC1551A]
 gi|328459585|gb|AEB05008.1| hypothetical protein TBSG_02879 [Mycobacterium tuberculosis KZN 
4207]
Length=66

 Score =  100 bits (248),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 49/49 (100%), Positives = 49/49 (100%), Gaps = 0/49 (0%)

Query  1   MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD  49
           MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD
Sbjct  18  MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD  66


>gi|15608259|ref|NP_215635.1| hypothetical protein Rv1119c [Mycobacterium tuberculosis H37Rv]
 gi|31792313|ref|NP_854806.1| hypothetical protein Mb1150c [Mycobacterium bovis AF2122/97]
 gi|121637051|ref|YP_977274.1| hypothetical protein BCG_1180c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 30 more sequence titles
 
gi|148660905|ref|YP_001282428.1| hypothetical protein MRA_1128A [Mycobacterium tuberculosis H37Ra]
 gi|148822333|ref|YP_001287087.1| hypothetical protein TBFG_11142 [Mycobacterium tuberculosis F11]
 gi|167969255|ref|ZP_02551532.1| hypothetical protein MtubH3_14995 [Mycobacterium tuberculosis 
H37Ra]
 gi|224989524|ref|YP_002644211.1| hypothetical protein JTY_1153 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|254550117|ref|ZP_05140564.1| hypothetical protein Mtube_06614 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|289569113|ref|ZP_06449340.1| hypothetical protein TBJG_01618 [Mycobacterium tuberculosis T17]
 gi|289744863|ref|ZP_06504241.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289753186|ref|ZP_06512564.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
 gi|289757209|ref|ZP_06516587.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|294993301|ref|ZP_06798992.1| hypothetical protein Mtub2_02027 [Mycobacterium tuberculosis 
210]
 gi|297633659|ref|ZP_06951439.1| hypothetical protein MtubK4_06039 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297730646|ref|ZP_06959764.1| hypothetical protein MtubKR_06129 [Mycobacterium tuberculosis 
KZN R506]
 gi|306783831|ref|ZP_07422153.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium tuberculosis SUMu003]
 gi|313657976|ref|ZP_07814856.1| hypothetical protein MtubKV_06134 [Mycobacterium tuberculosis 
KZN V2475]
 gi|339631185|ref|YP_004722827.1| hypothetical protein MAF_11350 [Mycobacterium africanum GM041182]
 gi|2117213|emb|CAB09051.1| HYPOTHETICAL PROTEIN Rv1119c [Mycobacterium tuberculosis H37Rv]
 gi|31617901|emb|CAD94011.1| HYPOTHETICAL PROTEIN Mb1150c [Mycobacterium bovis AF2122/97]
 gi|121492698|emb|CAL71167.1| Hypothetical protein BCG_1180c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|148505057|gb|ABQ72866.1| hypothetical protein MRA_1128A [Mycobacterium tuberculosis H37Ra]
 gi|148720860|gb|ABR05485.1| hypothetical protein TBFG_11142 [Mycobacterium tuberculosis F11]
 gi|224772637|dbj|BAH25443.1| hypothetical protein JTY_1153 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|289542867|gb|EFD46515.1| hypothetical protein TBJG_01618 [Mycobacterium tuberculosis T17]
 gi|289685391|gb|EFD52879.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289693773|gb|EFD61202.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
 gi|289712773|gb|EFD76785.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|308331394|gb|EFP20245.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium tuberculosis SUMu003]
 gi|326904653|gb|EGE51586.1| hypothetical protein TBPG_02562 [Mycobacterium tuberculosis W-148]
 gi|339330541|emb|CCC26207.1| hypothetical protein MAF_11350 [Mycobacterium africanum GM041182]
 gi|341601067|emb|CCC63739.1| hypothetical protein BCGM_1146c [Mycobacterium bovis BCG str. 
Moreau RDJ]
 gi|344218949|gb|AEM99579.1| hypothetical protein MTCTRI2_1150 [Mycobacterium tuberculosis 
CTRI-2]
Length=49

 Score =  100 bits (248),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 49/49 (100%), Positives = 49/49 (100%), Gaps = 0/49 (0%)

Query  1   MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD  49
           MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD
Sbjct  1   MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD  49


>gi|118616046|ref|YP_904378.1| hypothetical protein MUL_0150 [Mycobacterium ulcerans Agy99]
 gi|118568156|gb|ABL02907.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
Length=235

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 34/56 (61%), Positives = 36/56 (65%), Gaps = 12/56 (21%)

Query  1    MTARVAGQAVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAP  44
            M ARVAGQAVGGQILV EPV DAV DC DIR             GSYRLF ++ AP
Sbjct  175  MAARVAGQAVGGQILVSEPVRDAVRDCGDIRVDDGRDVELKGFSGSYRLFGVETAP  230


>gi|183984311|ref|YP_001852602.1| hypothetical protein MMAR_4340 [Mycobacterium marinum M]
 gi|183177637|gb|ACC42747.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=274

 Score = 60.5 bits (145),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 33/56 (59%), Positives = 35/56 (63%), Gaps = 12/56 (21%)

Query  1    MTARVAGQAVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAP  44
            M ARVAGQA GGQILV EPV DAV DC DIR             GSYRLF ++ AP
Sbjct  214  MAARVAGQAGGGQILVSEPVRDAVRDCGDIRVDDGRDVELKGFSGSYRLFGVETAP  269


>gi|240171082|ref|ZP_04749741.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium kansasii ATCC 12478]
Length=277

 Score = 50.8 bits (120),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 30/61 (50%), Positives = 35/61 (58%), Gaps = 12/61 (19%)

Query  1    MTARVAGQAVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGPDL  48
            M ARVAGQA GG+I V +PV DAV DC  I F            GSYRLF++ + P  D 
Sbjct  217  MAARVAGQAAGGEIRVSQPVRDAVGDCDGIGFDEGCDVELKGFSGSYRLFAVTSPPVSDG  276

Query  49   D  49
            D
Sbjct  277  D  277


>gi|296169989|ref|ZP_06851595.1| adenylate/guanylate cyclase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295895348|gb|EFG75055.1| adenylate/guanylate cyclase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=274

 Score = 49.7 bits (117),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 25/51 (50%), Positives = 32/51 (63%), Gaps = 12/51 (23%)

Query  11   GGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGPDLD  49
            GG++LV +PV DA+SDC DIRF            GSYRLF+++A   PD D
Sbjct  224  GGEVLVSQPVRDALSDCDDIRFDDGRDVELKGFSGSYRLFAVEAPADPDRD  274


>gi|254819690|ref|ZP_05224691.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium intracellulare ATCC 13950]
Length=277

 Score = 42.0 bits (97),  Expect = 0.034, Method: Compositional matrix adjust.
 Identities = 25/53 (48%), Positives = 32/53 (61%), Gaps = 14/53 (26%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLD--AAPGPD  47
            A GG+ILV +PV DA+S+   IRF            GSYRLF+++  A PGPD
Sbjct  225  AAGGEILVSQPVRDALSESEGIRFDGGRDVELKGFSGSYRLFAVEPSADPGPD  277


>gi|336458740|gb|EGO37700.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=272

 Score = 40.4 bits (93),  Expect = 0.087, Method: Compositional matrix adjust.
 Identities = 23/51 (46%), Positives = 30/51 (59%), Gaps = 12/51 (23%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGPD  47
            A GG+ILV +PV DA+S    IRF            G+YRLF++ A+P PD
Sbjct  222  AAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD  272


>gi|41408770|ref|NP_961606.1| hypothetical protein MAP2672 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397128|gb|AAS04989.1| hypothetical protein MAP_2672 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=223

 Score = 40.4 bits (93),  Expect = 0.097, Method: Compositional matrix adjust.
 Identities = 23/51 (46%), Positives = 30/51 (59%), Gaps = 12/51 (23%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGPD  47
            A GG+ILV +PV DA+S    IRF            G+YRLF++ A+P PD
Sbjct  173  AAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD  223


>gi|118464216|ref|YP_880496.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium avium 104]
 gi|118165503|gb|ABK66400.1| adenylate and Guanylate cyclase catalytic domain protein [Mycobacterium 
avium 104]
Length=272

 Score = 38.5 bits (88),  Expect = 0.35, Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 12/50 (24%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGP  46
            A GG+ILV +PV DA+S    IRF            G+YRLF++ A+P P
Sbjct  222  AAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDP  271


>gi|254774128|ref|ZP_05215644.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium avium subsp. avium ATCC 25291]
Length=275

 Score = 38.5 bits (88),  Expect = 0.36, Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 12/50 (24%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGP  46
            A GG+ILV +PV DA+S    IRF            G+YRLF++ A+P P
Sbjct  225  AAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDP  274


>gi|54124769|gb|AAV30108.1| Cya1120 [Mycobacterium avium]
Length=222

 Score = 38.1 bits (87),  Expect = 0.44, Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 12/50 (24%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDAAPGP  46
            A GG+ILV +PV DA+S    IRF            G+YRLF++ A+P P
Sbjct  172  AAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDP  221


>gi|126434113|ref|YP_001069804.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS]
 gi|126233913|gb|ABN97313.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS]
Length=279

 Score = 37.4 bits (85),  Expect = 0.68, Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 25/44 (57%), Gaps = 0/44 (0%)

Query  3    ARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGP  46
            ARVA  A GGQILV E +  AV + A I FG+ R   L   P P
Sbjct  225  ARVADLADGGQILVSEALRGAVGEDAGIEFGTRRDVELKGLPAP  268


>gi|342861708|ref|ZP_08718354.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium colombiense CECT 3035]
 gi|342130842|gb|EGT84138.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium colombiense CECT 3035]
Length=277

 Score = 36.6 bits (83),  Expect = 1.4, Method: Compositional matrix adjust.
 Identities = 21/46 (46%), Positives = 29/46 (64%), Gaps = 12/46 (26%)

Query  9    AVGGQILVGEPVHDAVSDCADIRF------------GSYRLFSLDA  42
            AVGGQILV +PV DA++D   IRF            G+YRLF++++
Sbjct  225  AVGGQILVSQPVRDALADSDGIRFDDGRNVELKGFSGTYRLFAVES  270


>gi|108798513|ref|YP_638710.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS]
 gi|119867613|ref|YP_937565.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS]
 gi|108768932|gb|ABG07654.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS]
 gi|119693702|gb|ABL90775.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS]
Length=279

 Score = 36.6 bits (83),  Expect = 1.4, Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 25/44 (57%), Gaps = 0/44 (0%)

Query  3    ARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGP  46
            ARVA  A GGQILV E +  AV + A I FG+ R   L   P P
Sbjct  225  ARVADLADGGQILVSEALRGAVGEDAGIDFGTRRDVELKGLPAP  268


>gi|333922094|ref|YP_004495675.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Amycolicicoccus subflavus DQS3-9A1]
 gi|333484315|gb|AEF42875.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Amycolicicoccus subflavus DQS3-9A1]
Length=271

 Score = 33.9 bits (76),  Expect = 9.4, Method: Compositional matrix adjust.
 Identities = 19/45 (43%), Positives = 23/45 (52%), Gaps = 0/45 (0%)

Query  1    MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPG  45
            + ARVA QA GG+ LV   V  A+ D   +RF   R  SL    G
Sbjct  209  LAARVADQASGGETLVSGQVRAAIRDGVPVRFSEERRVSLKGLDG  253



Lambda     K      H
   0.321    0.140    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 131889178584


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40