BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1120c Length=164 Score E Sequences producing significant alignments: (Bits) Value gi|15608260|ref|NP_215636.1| hypothetical protein Rv1120c [Mycob... 331 3e-89 gi|31792314|ref|NP_854807.1| hypothetical protein Mb1151c [Mycob... 329 8e-89 gi|294993302|ref|ZP_06798993.1| hypothetical protein Mtub2_02032... 293 6e-78 gi|340626133|ref|YP_004744585.1| adenylate and guanylate cyclase... 287 3e-76 gi|240171082|ref|ZP_04749741.1| adenylate and guanylate cyclase ... 253 7e-66 gi|183984311|ref|YP_001852602.1| hypothetical protein MMAR_4340 ... 249 8e-65 gi|118616046|ref|YP_904378.1| hypothetical protein MUL_0150 [Myc... 247 4e-64 gi|254819690|ref|ZP_05224691.1| adenylate and guanylate cyclase ... 246 7e-64 gi|296169989|ref|ZP_06851595.1| adenylate/guanylate cyclase [Myc... 246 1e-63 gi|342861708|ref|ZP_08718354.1| adenylate and guanylate cyclase ... 244 2e-63 gi|41408770|ref|NP_961606.1| hypothetical protein MAP2672 [Mycob... 244 2e-63 gi|336458740|gb|EGO37700.1| family 3 adenylate cyclase [Mycobact... 243 7e-63 gi|254774128|ref|ZP_05215644.1| adenylate and guanylate cyclase ... 243 7e-63 gi|118464216|ref|YP_880496.1| adenylate and guanylate cyclase ca... 243 9e-63 gi|54124769|gb|AAV30108.1| Cya1120 [Mycobacterium avium] 242 1e-62 gi|333989712|ref|YP_004522326.1| hypothetical protein JDM601_107... 221 4e-56 gi|145222679|ref|YP_001133357.1| putative adenylate/guanylate cy... 201 4e-50 gi|120405565|ref|YP_955394.1| putative adenylate/guanylate cycla... 196 1e-48 gi|108801056|ref|YP_641253.1| adenylate/guanylate cyclase [Mycob... 192 1e-47 gi|126436893|ref|YP_001072584.1| putative adenylate/guanylate cy... 192 1e-47 gi|333922094|ref|YP_004495675.1| adenylate and guanylate cyclase... 185 2e-45 gi|108798513|ref|YP_638710.1| adenylate/guanylate cyclase [Mycob... 132 2e-29 gi|126434113|ref|YP_001069804.1| putative adenylate/guanylate cy... 130 7e-29 gi|145222370|ref|YP_001133048.1| putative adenylate/guanylate cy... 122 2e-26 gi|311744457|ref|ZP_07718258.1| adenylate/guanylate cyclase [Aer... 114 4e-24 gi|332717292|ref|YP_004444758.1| adenylate/guanylate cyclase [Ag... 67.4 7e-10 gi|338820921|gb|EGP54891.1| adenylate/guanylate cyclase [Agrobac... 65.1 3e-09 gi|338972567|ref|ZP_08627940.1| adenylate cyclase [Bradyrhizobia... 63.5 1e-08 gi|240170151|ref|ZP_04748810.1| putative hydrolase [Mycobacteriu... 63.2 1e-08 gi|13472848|ref|NP_104415.1| hypothetical protein mll3269 [Mesor... 62.8 1e-08 gi|227822407|ref|YP_002826379.1| putative guanylate/adenylate cy... 62.0 3e-08 gi|291303661|ref|YP_003514939.1| putative adenylate/guanylate cy... 62.0 3e-08 gi|190891688|ref|YP_001978230.1| gualylate cyclase [Rhizobium et... 61.2 5e-08 gi|327193717|gb|EGE60597.1| putative gualylate cyclase protein [... 61.2 5e-08 gi|218661690|ref|ZP_03517620.1| putative gualylate cyclase prote... 60.5 7e-08 gi|209549251|ref|YP_002281168.1| adenylate/guanylate cyclase [Rh... 60.5 8e-08 gi|240172380|ref|ZP_04751039.1| adenylate/guanylate cyclase [Myc... 60.5 9e-08 gi|171915697|ref|ZP_02931167.1| regulatory protein, LuxR [Verruc... 59.7 1e-07 gi|218508532|ref|ZP_03506410.1| adenylate/guanylate cyclase prot... 59.7 2e-07 gi|190891682|ref|YP_001978224.1| adenylate/guanylate cyclase [Rh... 59.3 2e-07 gi|218662623|ref|ZP_03518553.1| adenylate/guanylate cyclase prot... 59.3 2e-07 gi|86357650|ref|YP_469542.1| gualylate cyclase [Rhizobium etli C... 58.9 2e-07 gi|86357644|ref|YP_469536.1| adenylate/guanylate cyclase [Rhizob... 58.9 2e-07 gi|218510243|ref|ZP_03508121.1| putative gualylate cyclase prote... 58.9 2e-07 gi|342859507|ref|ZP_08716161.1| hydrolase, alpha/beta hydrolase ... 58.9 2e-07 gi|126433867|ref|YP_001069558.1| adenylyl cyclase class-3/4/guan... 58.5 3e-07 gi|83592407|ref|YP_426159.1| adenylate/guanylate cyclase [Rhodos... 57.4 6e-07 gi|298525395|ref|ZP_07012804.1| conserved hypothetical protein [... 57.4 7e-07 gi|289569983|ref|ZP_06450210.1| lignin peroxidase lipJ [Mycobact... 57.0 9e-07 gi|289753995|ref|ZP_06513373.1| lignin peroxidase lipJ [Mycobact... 57.0 9e-07 >gi|15608260|ref|NP_215636.1| hypothetical protein Rv1120c [Mycobacterium tuberculosis H37Rv] gi|15840558|ref|NP_335595.1| hypothetical protein MT1152 [Mycobacterium tuberculosis CDC1551] gi|121637052|ref|YP_977275.1| hypothetical protein BCG_1181c [Mycobacterium bovis BCG str. Pasteur 1173P2] 51 more sequence titles Length=164 Score = 331 bits (848), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 164/164 (100%), Positives = 164/164 (100%), Gaps = 0/164 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS Sbjct 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC Sbjct 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 164 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ Sbjct 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 164 >gi|31792314|ref|NP_854807.1| hypothetical protein Mb1151c [Mycobacterium bovis AF2122/97] gi|31617902|emb|CAD94012.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97] Length=164 Score = 329 bits (843), Expect = 8e-89, Method: Compositional matrix adjust. Identities = 163/164 (99%), Positives = 163/164 (99%), Gaps = 0/164 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPD RVVILFS Sbjct 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDARVVILFS 60 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC Sbjct 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 164 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ Sbjct 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 164 >gi|294993302|ref|ZP_06798993.1| hypothetical protein Mtub2_02032 [Mycobacterium tuberculosis 210] Length=186 Score = 293 bits (750), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 149/163 (92%), Positives = 150/163 (93%), Gaps = 0/163 (0%) Query 2 LSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFSD 61 LSGG E+ K LVRKE F VRSSIEDPADWAEVERPDLARVTPDGRVVILFSD Sbjct 24 LSGGPESGKDGLADRELVRKEVFERPVRSSIEDPADWAEVERPDLARVTPDGRVVILFSD 83 Query 62 IEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCG 121 IEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCG Sbjct 84 IEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCG 143 Query 122 IDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 164 IDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ Sbjct 144 IDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ 186 >gi|340626133|ref|YP_004744585.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium canettii CIPT 140010059] gi|340004323|emb|CCC43465.1| adenylate and guanylate cyclase catalytic domain protein [Mycobacterium canettii CIPT 140010059] Length=511 Score = 287 bits (735), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 143/149 (96%), Positives = 145/149 (98%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS Sbjct 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAF+RAEQAVRC Sbjct 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFSRAEQAVRC 120 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GID+QDALR SAKRKRNQGIRVRIG G Sbjct 121 GIDVQDALRKSAKRKRNQGIRVRIGIHTG 149 >gi|240171082|ref|ZP_04749741.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium kansasii ATCC 12478] Length=277 Score = 253 bits (646), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 126/149 (85%), Positives = 133/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVKTVWQTANLVRKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 53 LLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 112 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI AHDK++HELV R SGH+V SQGDGFM+AFARAEQA+RC Sbjct 113 DIEESTALNERIGDRAWVKLIAAHDKMIHELVERRSGHVVKSQGDGFMVAFARAEQALRC 172 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 IDIQDAL AKRKR IRVRIG G Sbjct 173 AIDIQDALHREAKRKRRNVIRVRIGIHMG 201 >gi|183984311|ref|YP_001852602.1| hypothetical protein MMAR_4340 [Mycobacterium marinum M] gi|183177637|gb|ACC42747.1| conserved hypothetical protein [Mycobacterium marinum M] Length=274 Score = 249 bits (637), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 125/149 (84%), Positives = 132/149 (89%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +L+GGREAVKTVWQTANL+RKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 50 LLTGGREAVKTVWQTANLMRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 109 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLIGAHDK+VHE V R GH+V SQGDGFMIAFARAEQAVRC Sbjct 110 DIEESTALNERIGDRAWVKLIGAHDKMVHEFVHRHGGHVVKSQGDGFMIAFARAEQAVRC 169 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 G+DIQ AL AKRK GIRVRIG G Sbjct 170 GLDIQRALSREAKRKPRNGIRVRIGIHMG 198 >gi|118616046|ref|YP_904378.1| hypothetical protein MUL_0150 [Mycobacterium ulcerans Agy99] gi|118568156|gb|ABL02907.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99] Length=235 Score = 247 bits (631), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 123/149 (83%), Positives = 131/149 (88%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +L+GGREAVKTVWQTANL+RKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 11 LLTGGREAVKTVWQTANLMRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 70 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEEST L+ERIG+R WVKLIGAHDK+VHE V R GH+V SQGDGFMIAFARAEQAVRC Sbjct 71 DIEESTVLNERIGNRAWVKLIGAHDKMVHEFVHRHGGHVVKSQGDGFMIAFARAEQAVRC 130 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 G+DIQ AL AKRK GIRVRIG G Sbjct 131 GLDIQHALSREAKRKPRNGIRVRIGIHMG 159 >gi|254819690|ref|ZP_05224691.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium intracellulare ATCC 13950] Length=277 Score = 246 bits (629), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 124/149 (84%), Positives = 134/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVKTVW TANLVRKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 53 LLSGGREAVKTVWNTANLVRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 112 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LV+R SGH+V SQGDGFMIAFARAE+AVRC Sbjct 113 DIEESTALNERIGDRAWVKLISSHDKLVSDLVQRRSGHVVKSQGDGFMIAFARAEEAVRC 172 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GID+Q ALR A RKR++ IRVRIG G Sbjct 173 GIDLQRALRRDANRKRHEEIRVRIGIHMG 201 >gi|296169989|ref|ZP_06851595.1| adenylate/guanylate cyclase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895348|gb|EFG75055.1| adenylate/guanylate cyclase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=274 Score = 246 bits (627), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 122/149 (82%), Positives = 133/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVK VW TANL+RKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 50 LLSGGREAVKRVWNTANLLRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 109 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI AHDKLV +LV++ SGH+V SQGDGFMIAFARA+QAVRC Sbjct 110 DIEESTALNERIGDRAWVKLIAAHDKLVSDLVQKRSGHVVKSQGDGFMIAFARADQAVRC 169 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GID+Q ALR AKRKR+ +RVRIG G Sbjct 170 GIDLQHALRKDAKRKRHTELRVRIGIHMG 198 >gi|342861708|ref|ZP_08718354.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium colombiense CECT 3035] gi|342130842|gb|EGT84138.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium colombiense CECT 3035] Length=277 Score = 244 bits (624), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 122/149 (82%), Positives = 133/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVK VW TANL+RKEGFGAAVRSSIED ADWAEVERPDLARVTPDGRVVILFS Sbjct 53 LLSGGREAVKRVWNTANLMRKEGFGAAVRSSIEDLADWAEVERPDLARVTPDGRVVILFS 112 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LV+R SGH+V SQGDGFMIAFARA+QAVRC Sbjct 113 DIEESTALNERIGDRAWVKLISSHDKLVSDLVQRRSGHVVKSQGDGFMIAFARADQAVRC 172 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GID+Q ALR A RKR++ IRVRIG G Sbjct 173 GIDLQRALRRDANRKRHEEIRVRIGIHMG 201 >gi|41408770|ref|NP_961606.1| hypothetical protein MAP2672 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397128|gb|AAS04989.1| hypothetical protein MAP_2672 [Mycobacterium avium subsp. paratuberculosis K-10] Length=223 Score = 244 bits (624), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 121/149 (82%), Positives = 134/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 ML+GGREAVKTVW TANLVRKEGFGAAVRSSIE+ ADWAEVERPDLARVTPDGRVVILF+ Sbjct 1 MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT 60 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LVRR SGH+V SQGDGFM+AFAR EQAVRC Sbjct 61 DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC 120 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GI++Q ALR +A RKR++ IRVRIG G Sbjct 121 GIELQRALRRNANRKRHEEIRVRIGIHMG 149 >gi|336458740|gb|EGO37700.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis S397] Length=272 Score = 243 bits (620), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 120/149 (81%), Positives = 134/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +L+GGREAVKTVW TANLVRKEGFGAAVRSSIE+ ADWAEVERPDLARVTPDGRVVILF+ Sbjct 50 LLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT 109 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LVRR SGH+V SQGDGFM+AFAR EQAVRC Sbjct 110 DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC 169 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GI++Q ALR +A RKR++ IRVRIG G Sbjct 170 GIELQHALRRNANRKRHEEIRVRIGIHMG 198 >gi|254774128|ref|ZP_05215644.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] Length=275 Score = 243 bits (620), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 120/149 (81%), Positives = 134/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +L+GGREAVKTVW TANLVRKEGFGAAVRSSIE+ ADWAEVERPDLARVTPDGRVVILF+ Sbjct 53 LLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT 112 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LVRR SGH+V SQGDGFM+AFAR EQAVRC Sbjct 113 DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC 172 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GI++Q ALR +A RKR++ IRVRIG G Sbjct 173 GIELQRALRRNANRKRHEEIRVRIGIHMG 201 >gi|118464216|ref|YP_880496.1| adenylate and guanylate cyclase catalytic domain-containing protein [Mycobacterium avium 104] gi|118165503|gb|ABK66400.1| adenylate and Guanylate cyclase catalytic domain protein [Mycobacterium avium 104] Length=272 Score = 243 bits (619), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 120/149 (81%), Positives = 134/149 (90%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +L+GGREAVKTVW TANLVRKEGFGAAVRSSIE+ ADWAEVERPDLARVTPDGRVVILF+ Sbjct 50 LLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT 109 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI +HDKLV +LVRR SGH+V SQGDGFM+AFAR EQAVRC Sbjct 110 DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC 169 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 GI++Q ALR +A RKR++ IRVRIG G Sbjct 170 GIELQRALRRNANRKRHEEIRVRIGIHMG 198 >gi|54124769|gb|AAV30108.1| Cya1120 [Mycobacterium avium] Length=222 Score = 242 bits (618), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 120/148 (82%), Positives = 133/148 (90%), Gaps = 0/148 (0%) Query 2 LSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFSD 61 L+GGREAVKTVW TANLVRKEGFGAAVRSSIE+ ADWAEVERPDLARVTPDGRVVILF+D Sbjct 1 LAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFTD 60 Query 62 IEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCG 121 IEESTAL+ERIGDR WVKLI +HDKLV +LVRR SGH+V SQGDGFM+AFAR EQAVRCG Sbjct 61 IEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRCG 120 Query 122 IDIQDALRNSAKRKRNQGIRVRIGTTWG 149 I++Q ALR +A RKR++ IRVRIG G Sbjct 121 IELQRALRRNANRKRHEEIRVRIGIHMG 148 >gi|333989712|ref|YP_004522326.1| hypothetical protein JDM601_1071 [Mycobacterium sp. JDM601] gi|333485679|gb|AEF35071.1| conserved hypothetical protein [Mycobacterium sp. JDM601] Length=273 Score = 221 bits (562), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 110/149 (74%), Positives = 122/149 (82%), Gaps = 0/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVKTVWQTANLVRK+GFGAAVRSSIE+ ADWAEVERPDLAR+TPDG VVILF+ Sbjct 55 LLSGGREAVKTVWQTANLVRKQGFGAAVRSSIEELADWAEVERPDLARLTPDGHVVILFT 114 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR WVKLI HD++V VR GH+V SQGDG+MIAFA+ EQAVRC Sbjct 115 DIEESTALNERIGDRAWVKLIARHDEMVQRTVREHRGHVVKSQGDGYMIAFAQPEQAVRC 174 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 IDIQ L+ RK IRVRIG G Sbjct 175 AIDIQRGLQQRRGRKPQHPIRVRIGVHMG 203 >gi|145222679|ref|YP_001133357.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315443143|ref|YP_004076022.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] gi|145215165|gb|ABP44569.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315261446|gb|ADT98187.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] Length=263 Score = 201 bits (510), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 98/149 (66%), Positives = 122/149 (82%), Gaps = 5/149 (3%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 ++SGG +AVKTVWQTAN++RK+GFGAAVRSSIE+ ADWAEVERPDLAR++ +GR+ I+FS Sbjct 46 LVSGGTKAVKTVWQTANILRKDGFGAAVRSSIEELADWAEVERPDLARLSLNGRLTIMFS 105 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR +V+LIG HDK V + V + GH+V SQGDGFM+AFA+ EQAVRC Sbjct 106 DIEESTALNERIGDRAFVRLIGRHDKSVRKFVDKHEGHVVKSQGDGFMVAFAKPEQAVRC 165 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 G+DIQ +L +R IRVR+G G Sbjct 166 GLDIQHSL-----ARRPNDIRVRMGVHTG 189 >gi|120405565|ref|YP_955394.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] gi|119958383|gb|ABM15388.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] Length=261 Score = 196 bits (497), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 98/149 (66%), Positives = 119/149 (80%), Gaps = 5/149 (3%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +++G +AVKTVWQTAN++R++GFGAAVRSSIE+ ADWAEVERPDLAR+ P+GRV I+FS Sbjct 44 LVTGSTKAVKTVWQTANILRRDGFGAAVRSSIEELADWAEVERPDLARLAPNGRVAIMFS 103 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIEESTAL+ERIGDR +V+L+G HDK V V G++V SQGDGFM+AFAR EQAVRC Sbjct 104 DIEESTALNERIGDRAFVRLLGRHDKPVRRHVDAHDGYVVKSQGDGFMVAFARPEQAVRC 163 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 G+ IQ +L KR GIRVRIG G Sbjct 164 GLAIQHSL-----DKRPNGIRVRIGIHVG 187 >gi|108801056|ref|YP_641253.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119870198|ref|YP_940150.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] gi|108771475|gb|ABG10197.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119696287|gb|ABL93360.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] Length=271 Score = 192 bits (489), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 98/149 (66%), Positives = 112/149 (76%), Gaps = 5/149 (3%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVK VWQTANLVR++GFG A+ SSIED ADW EVERPDLAR+ P GRV ILFS Sbjct 49 LLSGGREAVKHVWQTANLVREKGFGGAITSSIEDLADWFEVERPDLARLAPHGRVAILFS 108 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIE+STAL+ RIGDR W +LIG H + V VR GH+V SQGDGFM+AFA E AVRC Sbjct 109 DIEDSTALNNRIGDRAWARLIGRHARSVQRHVREHDGHVVKSQGDGFMVAFASPENAVRC 168 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 I +Q +L R+R GIRVRIG G Sbjct 169 AIALQHSL-----RRRPNGIRVRIGIHTG 192 >gi|126436893|ref|YP_001072584.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] gi|126236693|gb|ABO00094.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] Length=271 Score = 192 bits (489), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 98/149 (66%), Positives = 112/149 (76%), Gaps = 5/149 (3%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSGGREAVK VWQTANLVR++GFG A+ SSIED ADW EVERPDLAR+ P GRV ILFS Sbjct 49 LLSGGREAVKHVWQTANLVREKGFGGAITSSIEDLADWFEVERPDLARLAPHGRVAILFS 108 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DIE+STAL+ RIGDR W +LIG H + V VR GH+V SQGDGFM+AFA E AVRC Sbjct 109 DIEDSTALNNRIGDRAWARLIGRHARSVQRHVREHDGHVVKSQGDGFMVAFASPENAVRC 168 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 I +Q +L R+R GIRVRIG G Sbjct 169 AIALQHSL-----RRRPNGIRVRIGIHTG 192 >gi|333922094|ref|YP_004495675.1| adenylate and guanylate cyclase catalytic domain-containing protein [Amycolicicoccus subflavus DQS3-9A1] gi|333484315|gb|AEF42875.1| adenylate and guanylate cyclase catalytic domain-containing protein [Amycolicicoccus subflavus DQS3-9A1] Length=271 Score = 185 bits (469), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 90/149 (61%), Positives = 116/149 (78%), Gaps = 1/149 (0%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 +LSG REAVKTVWQTANLVR +G GAA+R+S+E+ A+WAEVERPDLAR+T +G VVI FS Sbjct 46 LLSGSREAVKTVWQTANLVRSKGLGAAMRTSVEELANWAEVERPDLARLTKNGSVVIFFS 105 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 DI+ STAL+E +GDR WVKL+ H+KL+ + V GH++ SQGDGFM+AF+R +QAV C Sbjct 106 DIQGSTALNEELGDRAWVKLLERHEKLIRQCVDAHGGHVIKSQGDGFMVAFSRPDQAVLC 165 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 ++IQ+AL ++ R IRVRIG G Sbjct 166 SMEIQNAL-DTLSWSRRHAIRVRIGIHMG 193 >gi|108798513|ref|YP_638710.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119867613|ref|YP_937565.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] gi|108768932|gb|ABG07654.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119693702|gb|ABL90775.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] Length=279 Score = 132 bits (331), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 75/145 (52%), Positives = 94/145 (65%), Gaps = 5/145 (3%) Query 8 AVKTVW---QTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFSDIEE 64 A+KTV QTA+ + + GA+VRSSIED A WA VERPDLAR+T DGRVV++FSDIE Sbjct 65 AIKTVANTVQTADSIIRRQLGASVRSSIEDLAGWARVERPDLARITADGRVVLVFSDIEG 124 Query 65 STALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDI 124 ST + +GDR WV+L+ H++L+ V G +V +QGDGFMIAF AVRC I + Sbjct 125 STQRNATLGDRDWVELLERHEQLIRRQVTAHRGFVVKNQGDGFMIAFPEPAGAVRCCIAV 184 Query 125 QDALRNSAKRKRNQGIRVRIGTTWG 149 Q AL GIRVR+G G Sbjct 185 QQALLQDG--YATDGIRVRMGVHVG 207 >gi|126434113|ref|YP_001069804.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] gi|126233913|gb|ABN97313.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] Length=279 Score = 130 bits (327), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 75/145 (52%), Positives = 93/145 (65%), Gaps = 5/145 (3%) Query 8 AVKTVW---QTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFSDIEE 64 A+KTV QTA+ + + GA+VRSSIED A WA VERPDLAR+T DGRVV++FSDIE Sbjct 65 AIKTVANTVQTADSIIRRQLGASVRSSIEDLAGWARVERPDLARITADGRVVMVFSDIEG 124 Query 65 STALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDI 124 ST + +GDR WVKL+ H++L+ V G +V +QGDGFMIAF AVRC I + Sbjct 125 STQRNATLGDRDWVKLLERHEQLIRRQVAAHRGFVVKNQGDGFMIAFPEPAGAVRCCIAV 184 Query 125 QDALRNSAKRKRNQGIRVRIGTTWG 149 Q AL IRVR+G G Sbjct 185 QQALLQDG--YVTDAIRVRMGVHVG 207 >gi|145222370|ref|YP_001133048.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|145214856|gb|ABP44260.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] Length=189 Score = 122 bits (305), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 66/125 (53%), Positives = 85/125 (68%), Gaps = 4/125 (3%) Query 8 AVKTVW---QTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARV-TPDGRVVILFSDIE 63 AV+TV TA+ + ++G G +VRSSIED A WA +ERPDLARV + DG VV++FSDIE Sbjct 59 AVRTVMNTVHTADAIVRKGIGGSVRSSIEDLAGWARIERPDLARVVSADGTVVLVFSDIE 118 Query 64 ESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGID 123 ST L+ +GDR WVK + H+ L+ V GH+V +QGDGFMIAFA A+R D Sbjct 119 GSTELNASLGDRAWVKNLERHNTLIQRCVADHRGHVVKNQGDGFMIAFAEPADAIRSCCD 178 Query 124 IQDAL 128 +Q AL Sbjct 179 VQRAL 183 >gi|311744457|ref|ZP_07718258.1| adenylate/guanylate cyclase [Aeromicrobium marinum DSM 15272] gi|311312262|gb|EFQ82178.1| adenylate/guanylate cyclase [Aeromicrobium marinum DSM 15272] Length=272 Score = 114 bits (286), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 64/145 (45%), Positives = 90/145 (63%), Gaps = 1/145 (0%) Query 7 EAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVT-PDGRVVILFSDIEES 65 +AVK V ++A+++R G V SSIED +W +R + R PDG V + FSDIE S Sbjct 61 KAVKAVTESADILRTRGVSGLVASSIEDLTEWVREDRAAVERFAAPDGTVTVFFSDIEGS 120 Query 66 TALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDIQ 125 TAL+ER+GDR +VK++ HD+LV + GH+V +QGDGFM+ F ++ VR ++IQ Sbjct 121 TALNERLGDRAFVKVLARHDELVRTSLANHDGHVVKTQGDGFMVVFRQSADGVRAALEIQ 180 Query 126 DALRNSAKRKRNQGIRVRIGTTWGA 150 + L R R+ I VRIG GA Sbjct 181 ERLGRERGRLRSHDIAVRIGLHRGA 205 >gi|332717292|ref|YP_004444758.1| adenylate/guanylate cyclase [Agrobacterium sp. H13-3] gi|325063977|gb|ADY67667.1| adenylate/guanylate cyclase [Agrobacterium sp. H13-3] Length=270 Score = 67.4 bits (163), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 50/145 (35%), Positives = 67/145 (47%), Gaps = 10/145 (6%) Query 14 QTANLVRKEGFGAAVRSSIEDPADWAE-----VERP-DLARVTPD---GRVVILFSDIEE 64 +TA V +E G +E E ++ P LA ++ D G ILF+DI Sbjct 58 ETAQCVHREAHGFVASEVVEVALSAVEAFLGRIQDPLSLATISKDMDAGHRAILFTDIVG 117 Query 65 STALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDI 124 ST + R+GDR +L+ AHD LV + R SG V GDG M F+ AV C IDI Sbjct 118 STEMTARLGDRMAAELVRAHDALVRGCLGRRSGREVKHTGDGIMAVFSSVPFAVDCAIDI 177 Query 125 QDALRNSAKRKRNQGIRVRIGTTWG 149 Q + + I +RIG G Sbjct 178 QREF-HRYNSGNGEPIHIRIGLDCG 201 >gi|338820921|gb|EGP54891.1| adenylate/guanylate cyclase [Agrobacterium tumefaciens F2] Length=270 Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 43/99 (44%), Positives = 51/99 (52%), Gaps = 5/99 (5%) Query 53 GRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFA 112 G ILF+DI ST + R+GDR +LI AHD LV + R SG V GDG M FA Sbjct 106 GHRAILFTDIVGSTEMTARLGDRMAAELIRAHDALVRGCLGRRSGREVKHTGDGIMAVFA 165 Query 113 RAEQAVRCGIDIQDALRNSAKRKRNQG--IRVRIGTTWG 149 AV C IDIQ R + + G I +RIG G Sbjct 166 SIPFAVDCAIDIQ---REFHRYNIDSGEPIHIRIGLDCG 201 >gi|338972567|ref|ZP_08627940.1| adenylate cyclase [Bradyrhizobiaceae bacterium SG-6C] gi|338234352|gb|EGP09469.1| adenylate cyclase [Bradyrhizobiaceae bacterium SG-6C] Length=463 Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 37/103 (36%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D++ STAL ER+GD L+ AH + + E++ +G +V + GD M F R Sbjct 293 LTFLFTDLKGSTALYERVGDLAAFDLVRAHFRALLEIIASEAGAVVKTIGDAVMATFVRP 352 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 EQAV GI ++ A+ + Q + V+IG GA C V + Sbjct 353 EQAVAAGIRMRKAMDALNAERGTQDLLVKIGIHEGA-CLAVML 394 >gi|240170151|ref|ZP_04748810.1| putative hydrolase [Mycobacterium kansasii ATCC 12478] Length=356 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/123 (33%), Positives = 66/123 (54%), Gaps = 13/123 (10%) Query 29 RSSIEDPADWAEVERPDLARVTPDGRVV--ILFSDIEESTALDERIGDRTWVKLIGAHDK 86 R+S ++ A++ R + PD R++ +LF+DI +ST ++GDR W ++ AHD Sbjct 176 RASFQEIAEFLTGHRAQV----PDDRILATVLFTDIVDSTRCAAQLGDRDWRAVLDAHDA 231 Query 87 LVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGT 146 +V + + G V + GDGF+ F ++A+RC + I+DA+ GI VR G Sbjct 232 VVRSQLASFRGREVNTSGDGFLAMFDGPQRAIRCAMAIRDAV-------PALGIEVRAGL 284 Query 147 TWG 149 G Sbjct 285 HTG 287 >gi|13472848|ref|NP_104415.1| hypothetical protein mll3269 [Mesorhizobium loti MAFF303099] gi|14023595|dbj|BAB50201.1| mll3269 [Mesorhizobium loti MAFF303099] Length=471 Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 33/103 (33%), Positives = 60/103 (59%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ STAL ER+GD + L+ AH +++HE+V +G +V + GD M FA Sbjct 301 LTFLFTDLRGSTALYERVGDLSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATP 360 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++A+ + ++DA+R + + + ++IG G C V++ Sbjct 361 DRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGP-CIAVSM 402 >gi|227822407|ref|YP_002826379.1| putative guanylate/adenylate cyclase [Sinorhizobium fredii NGR234] gi|227341408|gb|ACP25626.1| putative guanylate/adenylate cyclase [Sinorhizobium fredii NGR234] Length=469 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 33/103 (33%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ ST L ER+GD L+ AH +++HE+V +G +V + GD M F Sbjct 299 LTFLFTDLRGSTELYERVGDLAAFDLVRAHFRVLHEIVAAEAGAVVKTIGDAVMATFPTP 358 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++AV + ++DA+RN + + + ++IG G C V + Sbjct 359 DRAVAAAMRMRDAMRNLNDERGREDLLLKIGIHEGP-CIAVNL 400 >gi|291303661|ref|YP_003514939.1| putative adenylate/guanylate cyclase [Stackebrandtia nassauensis DSM 44728] gi|290572881|gb|ADD45846.1| putative adenylate/guanylate cyclase [Stackebrandtia nassauensis DSM 44728] Length=532 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 32/90 (36%), Positives = 53/90 (59%), Gaps = 4/90 (4%) Query 43 RPDLARVTPDGRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTS 102 RPD P G V LF+DIE ST L +GD + +++ H +L+ + R++G + + Sbjct 6 RPD---ELPTGLVTFLFTDIEGSTRLAHTLGD-GYRRVLHEHRRLMRRIFTRYTGTELLT 61 Query 103 QGDGFMIAFARAEQAVRCGIDIQDALRNSA 132 +GD F +AF+ AE A+ +++Q AL+ A Sbjct 62 EGDSFFVAFSEAETALHAAVEVQLALKQHA 91 >gi|190891688|ref|YP_001978230.1| gualylate cyclase [Rhizobium etli CIAT 652] gi|190696967|gb|ACE91052.1| putative gualylate cyclase protein [Rhizobium etli CIAT 652] Length=278 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 43/114 (38%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Query 41 VERPDLA--RVTPD---GRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRW 95 + PD A + TP G ILF+DI ST + R+GDR +L+ AHD +V + + Sbjct 90 INDPDPAPGQSTPQMDPGHRAILFTDIVGSTEMTARLGDRMGTELVRAHDAIVRRCLGKN 149 Query 96 SGHMVTSQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 SG V GDG M AFA AV C + IQ ++ Q I +RIG G Sbjct 150 SGREVKHTGDGIMAAFAATTAAVECAMAIQQEFQHYNSGNNAQPIHIRIGLDCG 203 >gi|327193717|gb|EGE60597.1| putative gualylate cyclase protein [Rhizobium etli CNPAF512] Length=278 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 43/114 (38%), Positives = 57/114 (50%), Gaps = 5/114 (4%) Query 41 VERPDLA--RVTPD---GRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRW 95 + PD A + TP G ILF+DI ST + R+GDR +L+ AHD +V + + Sbjct 90 INDPDPAPGQSTPQMDPGHRAILFTDIVGSTEMTARLGDRMGTELVRAHDAIVRRCLGKN 149 Query 96 SGHMVTSQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 SG V GDG M AFA AV C + IQ ++ Q I +RIG G Sbjct 150 SGREVKHTGDGIMAAFAATTAAVECAMAIQQEFQHYNSGNNAQPIHIRIGLDCG 203 >gi|218661690|ref|ZP_03517620.1| putative gualylate cyclase protein [Rhizobium etli IE4771] Length=255 Score = 60.5 bits (145), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 38/97 (40%), Positives = 50/97 (52%), Gaps = 0/97 (0%) Query 53 GRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFA 112 G ILF+DI ST + R+GDR +L+ AHD +V + + SG V GDG M AFA Sbjct 84 GHRAILFTDIVGSTEMTARLGDRMGTELVRAHDAIVRRCLGKNSGREVKHTGDGIMAAFA 143 Query 113 RAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 AV C + IQ ++ Q I +RIG G Sbjct 144 ATTAAVECAMAIQQEFQHYNSGNNAQPIHIRIGIDCG 180 >gi|209549251|ref|YP_002281168.1| adenylate/guanylate cyclase [Rhizobium leguminosarum bv. trifolii WSM2304] gi|209535007|gb|ACI54942.1| adenylate/guanylate cyclase [Rhizobium leguminosarum bv. trifolii WSM2304] Length=275 Score = 60.5 bits (145), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 46/148 (32%), Positives = 65/148 (44%), Gaps = 13/148 (8%) Query 13 WQTANLVRKEGFGAAVRSSIEDPADWAE-----VERPDLA------RVTPDGRVVILFSD 61 +TA V +E G +E E + PD A + P G ILF+D Sbjct 57 METAQCVHREAHGFVAGEVVEVALSAVEAFLGRIHDPDPAPGQSSAEIDP-GHRAILFTD 115 Query 62 IEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCG 121 I ST + R+GDR +++ AHD +V + + SG V GDG M AF+ AV C Sbjct 116 IVGSTEMTARLGDRIGTEMVRAHDAIVRRCLGQNSGREVKHTGDGIMAAFSATTAAVECA 175 Query 122 IDIQDALRNSAKRKRNQGIRVRIGTTWG 149 + IQ + + I +RIG G Sbjct 176 MAIQKEFQ-LYNGGNTEPIHIRIGLDCG 202 >gi|240172380|ref|ZP_04751039.1| adenylate/guanylate cyclase [Mycobacterium kansasii ATCC 12478] Length=622 Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 35/96 (37%), Positives = 54/96 (57%), Gaps = 2/96 (2%) Query 54 RVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFAR 113 +VV+LF+D+ STAL ER+GD T L+ H L+ +VR G +V + GD M +F Sbjct 446 QVVLLFTDLRGSTALYERVGDATAYNLVREHFTLLAAIVRDHDGAVVKTIGDAVMASFTD 505 Query 114 AEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 +AVR + +Q A+ SA G+ +++G G Sbjct 506 PARAVRAALAMQAAI--SASAHAGGGLVLKVGVHAG 539 >gi|171915697|ref|ZP_02931167.1| regulatory protein, LuxR [Verrucomicrobium spinosum DSM 4136] Length=884 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 38/102 (38%), Positives = 58/102 (57%), Gaps = 2/102 (1%) Query 49 VTPDGRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFM 108 V P G + LFSDIE ST ++ D V L G HD+++ E+ SG++ + GD F Sbjct 3 VAPTGTITFLFSDIEGSTKKWDQHPDAMQVAL-GKHDRMLREIFAACSGYVFKTIGDAFC 61 Query 109 IAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGA 150 +AF A+ A+ ++ Q ALR++ R+ G+RVR+ GA Sbjct 62 VAFDTAQWALAAALECQRALRDADWREVG-GLRVRMALHTGA 102 >gi|218508532|ref|ZP_03506410.1| adenylate/guanylate cyclase protein [Rhizobium etli Brasil 5] Length=410 Score = 59.7 bits (143), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ STAL ER+GD L+ AH +++HE+V +G +V + GD M F Sbjct 298 LTFLFTDLRGSTALYERVGDLAAFDLVRAHFRVLHEIVATEAGAVVKTIGDAVMATFPSP 357 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++AV + +++A+R ++ + ++IG G C V + Sbjct 358 DRAVAAALRMREAMRRLNAEHGSEDLLLKIGIHEGP-CLAVNL 399 >gi|190891682|ref|YP_001978224.1| adenylate/guanylate cyclase [Rhizobium etli CIAT 652] gi|190696961|gb|ACE91046.1| adenylate/guanylate cyclase protein [Rhizobium etli CIAT 652] Length=468 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ STAL ER+GD L+ AH +++HE+V +G +V + GD M F Sbjct 298 LTFLFTDLRGSTALYERVGDLAAFDLVRAHFRVLHEIVATEAGAVVKTIGDAVMATFPSP 357 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++AV + +++A+R ++ + ++IG G C V + Sbjct 358 DRAVAAALRMREAMRRLNAEHGSEDLLLKIGIHEGP-CLAVNL 399 >gi|218662623|ref|ZP_03518553.1| adenylate/guanylate cyclase protein [Rhizobium etli IE4771] Length=468 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ STAL ER+GD L+ AH +++HE+V +G +V + GD M F Sbjct 298 LTFLFTDLRGSTALYERVGDLAAFDLVRAHFRVLHEIVATEAGAVVKTIGDAVMATFPSP 357 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++AV + +++A+R ++ + ++IG G C V + Sbjct 358 DRAVAAALRMREAMRRLNAEHGSEDLLLKIGIHEGP-CLAVNL 399 >gi|86357650|ref|YP_469542.1| gualylate cyclase [Rhizobium etli CFN 42] gi|86281752|gb|ABC90815.1| putative gualylate cyclase protein [Rhizobium etli CFN 42] Length=275 Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 50/146 (35%), Positives = 68/146 (47%), Gaps = 11/146 (7%) Query 14 QTANLVRKEGFGAAVRSSIEDPADWAE-----VERPDLA--RVTPD---GRVVILFSDIE 63 +T + V +E G +E E + PD A + TP G ILF+DI Sbjct 58 ETVHCVHREAHGFVANEVVEVALSAVEAFLGRINDPDPAPGQSTPQMDAGHRAILFTDIV 117 Query 64 ESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGID 123 ST + R+GDR +L+ AHD +V + + SG V GDG M AFA AV C + Sbjct 118 GSTEMTARLGDRMGTELVRAHDAIVRRCLGKNSGREVKHTGDGIMAAFAATTAAVECAMA 177 Query 124 IQDALRNSAKRKRNQGIRVRIGTTWG 149 IQ ++ K + I VRIG G Sbjct 178 IQQEFQHYNGSK-AEPIHVRIGLDCG 202 >gi|86357644|ref|YP_469536.1| adenylate/guanylate cyclase [Rhizobium etli CFN 42] gi|86281746|gb|ABC90809.1| adenylate/guanylate cyclase protein [Rhizobium etli CFN 42] Length=468 Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 57/103 (56%), Gaps = 1/103 (0%) Query 55 VVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARA 114 + LF+D+ STAL ER+GD L+ AH +++HE+V +G +V + GD M F Sbjct 298 LTFLFTDLRGSTALYERVGDLAAFDLVRAHFRVLHEIVATEAGAVVKTIGDAVMATFPSP 357 Query 115 EQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTI 157 ++AV + +++A+R ++ + ++IG G C V + Sbjct 358 DRAVAAALRMREAMRRLNAEHGSEDLLLKIGIHEGP-CLAVNL 399 >gi|218510243|ref|ZP_03508121.1| putative gualylate cyclase protein [Rhizobium etli Brasil 5] Length=278 Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/97 (39%), Positives = 49/97 (51%), Gaps = 0/97 (0%) Query 53 GRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFA 112 G ILF+DI ST + R+GDR +++ AHD +V + + SG V GDG M AFA Sbjct 107 GHRAILFTDIVGSTEMTARLGDRMGTEVVRAHDAIVRRCLGKNSGREVKHTGDGIMAAFA 166 Query 113 RAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 AV C + IQ + Q I +RIG G Sbjct 167 ATTAAVECAMAIQQEFEHYNSGNNAQPIHIRIGLDCG 203 >gi|342859507|ref|ZP_08716161.1| hydrolase, alpha/beta hydrolase family protein [Mycobacterium colombiense CECT 3035] gi|342133748|gb|EGT86951.1| hydrolase, alpha/beta hydrolase family protein [Mycobacterium colombiense CECT 3035] Length=428 Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/93 (37%), Positives = 49/93 (53%), Gaps = 7/93 (7%) Query 57 ILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQ 116 I+F+DI ST +GD W L+ HD++V ++R+SG V + GDGF+ F+ Sbjct 268 IMFTDIVGSTERAAALGDHRWRDLLDNHDRIVRHELQRFSGREVNTAGDGFVATFSSPSA 327 Query 117 AVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 A+ C I DA+ R GI VR+G G Sbjct 328 AIACADAIVDAV-------RVLGIEVRVGIHAG 353 >gi|126433867|ref|YP_001069558.1| adenylyl cyclase class-3/4/guanylyl cyclase [Mycobacterium sp. JLS] gi|126233667|gb|ABN97067.1| adenylyl cyclase class-3/4/guanylyl cyclase [Mycobacterium sp. JLS] Length=1087 Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 42/129 (33%), Positives = 67/129 (52%), Gaps = 16/129 (12%) Query 36 ADWAEVERPDLARVTPDG-----RVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHE 90 AD A E DL V PD R+ ILF+D+ +ST+L R+ T+ ++G + + V Sbjct 66 ADGANAEAEDLLAV-PDHPGEIRRLTILFADLVDSTSLSTRVEPETYRLVVGRYREQVVR 124 Query 91 LVRRWSGHMVTSQGDGFMIAFAR-------AEQAVRCGIDIQDA---LRNSAKRKRNQGI 140 +V R+ GH+ +++GDG + F A +AV G+DI + +A+R+ I Sbjct 125 IVERFGGHVCSTKGDGLLAVFGHPIAHEDDARRAVAAGLDITGGVARISEAARRRFGFDI 184 Query 141 RVRIGTTWG 149 VR+G G Sbjct 185 AVRVGVHRG 193 >gi|83592407|ref|YP_426159.1| adenylate/guanylate cyclase [Rhodospirillum rubrum ATCC 11170] gi|83575321|gb|ABC21872.1| adenylate/guanylate cyclase [Rhodospirillum rubrum ATCC 11170] Length=680 Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 43/149 (29%), Positives = 66/149 (45%), Gaps = 11/149 (7%) Query 1 MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFS 60 ML GR+A+ ++ G G + ADW P AR V I+F+ Sbjct 449 MLQAGRQAMG--------MKLAGGGEPFAPLPQLMADW---RAPQAARPATASTVAIVFT 497 Query 61 DIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRC 120 D+ ST ++ R GDR ++ H+ +V + R+ G V GDG M F QAV Sbjct 498 DMVGSTDINARFGDRHSHEITRVHNAIVRAALGRFDGREVKHTGDGIMATFPVVSQAVEA 557 Query 121 GIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 I++Q AL + + + +R+G G Sbjct 558 MIEVQKALAEHNRIAPDLRLDLRVGINAG 586 >gi|298525395|ref|ZP_07012804.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298495189|gb|EFI30483.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=462 Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 34/93 (37%), Positives = 46/93 (50%), Gaps = 7/93 (7%) Query 57 ILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQ 116 I+F+DI ST +GD W L+ HD +V ++R+ G V + GDGF+ F Sbjct 298 IMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDGFVATFTSPSA 357 Query 117 AVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 A+ C DI DA+ GI VRIG G Sbjct 358 AIACADDIVDAV-------ATLGIEVRIGIHAG 383 >gi|289569983|ref|ZP_06450210.1| lignin peroxidase lipJ [Mycobacterium tuberculosis T17] gi|289543737|gb|EFD47385.1| lignin peroxidase lipJ [Mycobacterium tuberculosis T17] Length=446 Score = 57.0 bits (136), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 34/93 (37%), Positives = 46/93 (50%), Gaps = 7/93 (7%) Query 57 ILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQ 116 I+F+DI ST +GD W L+ HD +V ++R+ G V + GDGF+ F Sbjct 298 IMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDGFVATFTSPSA 357 Query 117 AVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 A+ C DI DA+ GI VRIG G Sbjct 358 AIACADDIVDAV-------AALGIEVRIGIHAG 383 >gi|289753995|ref|ZP_06513373.1| lignin peroxidase lipJ [Mycobacterium tuberculosis EAS054] gi|289694582|gb|EFD62011.1| lignin peroxidase lipJ [Mycobacterium tuberculosis EAS054] Length=463 Score = 57.0 bits (136), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 34/93 (37%), Positives = 46/93 (50%), Gaps = 7/93 (7%) Query 57 ILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQ 116 I+F+DI ST +GD W L+ HD +V ++R+ G V + GDGF+ F Sbjct 298 IMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGREVNTAGDGFVATFTSPSA 357 Query 117 AVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWG 149 A+ C DI DA+ GI VRIG G Sbjct 358 AIACADDIVDAV-------AALGIEVRIGIHAG 383 Lambda K H 0.320 0.133 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 129330420882 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40