BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1139c

Length=166
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608279|ref|NP_215655.1|  hypothetical protein Rv1139c [Mycob...   327    3e-88
gi|289442570|ref|ZP_06432314.1|  conserved membrane protein [Myco...   326    9e-88
gi|340626153|ref|YP_004744605.1|  hypothetical protein MCAN_11501...   325    1e-87
gi|240172487|ref|ZP_04751146.1|  hypothetical protein MkanA1_2444...   289    8e-77
gi|183984284|ref|YP_001852575.1|  hypothetical protein MMAR_4314 ...   286    5e-76
gi|118616734|ref|YP_905066.1|  hypothetical protein MUL_0980 [Myc...   283    7e-75
gi|254820704|ref|ZP_05225705.1|  isoprenylcysteine carboxyl methy...   275    2e-72
gi|118464098|ref|YP_880524.1|  isoprenylcysteine carboxyl methylt...   272    2e-71
gi|254774155|ref|ZP_05215671.1|  isoprenylcysteine carboxyl methy...   270    4e-71
gi|296170027|ref|ZP_06851631.1|  isoprenylcysteine carboxyl methy...   270    7e-71
gi|336458769|gb|EGO37729.1|  hypothetical protein MAPs_10530 [Myc...   268    2e-70
gi|41408741|ref|NP_961577.1|  hypothetical protein MAP2643 [Mycob...   266    6e-70
gi|342861751|ref|ZP_08718397.1|  isoprenylcysteine carboxyl methy...   264    3e-69
gi|15840579|ref|NP_335616.1|  hypothetical protein MT1172 [Mycoba...   245    1e-63
gi|333990401|ref|YP_004523015.1|  hypothetical protein JDM601_176...   232    1e-59
gi|342861400|ref|ZP_08718048.1|  isoprenylcysteine carboxyl methy...   216    1e-54
gi|256391299|ref|YP_003112863.1|  isoprenylcysteine carboxyl meth...   214    3e-54
gi|145225717|ref|YP_001136395.1|  isoprenylcysteine carboxyl meth...   214    3e-54
gi|311895218|dbj|BAJ27626.1|  putative methyltransferase [Kitasat...   211    3e-53
gi|108799296|ref|YP_639493.1|  isoprenylcysteine carboxyl methylt...   211    4e-53
gi|126433694|ref|YP_001069385.1|  isoprenylcysteine carboxyl meth...   210    5e-53
gi|296164684|ref|ZP_06847250.1|  isoprenylcysteine carboxyl methy...   210    6e-53
gi|108798033|ref|YP_638230.1|  isoprenylcysteine carboxyl methylt...   209    1e-52
gi|317126612|ref|YP_004100724.1|  isoprenylcysteine carboxyl meth...   208    2e-52
gi|297190133|ref|ZP_06907531.1|  isoprenylcysteine carboxyl methy...   208    3e-52
gi|120402207|ref|YP_952036.1|  isoprenylcysteine carboxyl methylt...   206    6e-52
gi|182434264|ref|YP_001821983.1|  methyltransferase [Streptomyces...   206    6e-52
gi|284030487|ref|YP_003380418.1|  Isoprenylcysteine carboxyl meth...   206    8e-52
gi|326774777|ref|ZP_08234042.1|  Isoprenylcysteine carboxyl methy...   205    1e-51
gi|336322079|ref|YP_004602047.1|  Isoprenylcysteine carboxyl meth...   204    4e-51
gi|297201166|ref|ZP_06918563.1|  isoprenylcysteine carboxyl methy...   199    9e-50
gi|271967232|ref|YP_003341428.1|  hypothetical protein Sros_5950 ...   197    4e-49
gi|296129012|ref|YP_003636262.1|  Isoprenylcysteine carboxyl meth...   196    1e-48
gi|289766907|ref|ZP_06526285.1|  isoprenylcysteine carboxyl methy...   193    6e-48
gi|118467589|ref|YP_885213.1|  isoprenylcysteine carboxyl methylt...   193    8e-48
gi|291435054|ref|ZP_06574444.1|  isoprenylcysteine carboxyl methy...   192    1e-47
gi|296269923|ref|YP_003652555.1|  Isoprenylcysteine carboxyl meth...   192    1e-47
gi|334337018|ref|YP_004542170.1|  Isoprenylcysteine carboxyl meth...   192    2e-47
gi|239992518|ref|ZP_04713182.1|  methyltransferase [Streptomyces ...   191    2e-47
gi|84497357|ref|ZP_00996179.1|  hypothetical protein JNB_14223 [J...   191    2e-47
gi|21225930|ref|NP_631709.1|  hypothetical protein SCO7670 [Strep...   191    4e-47
gi|258655219|ref|YP_003204375.1|  isoprenylcysteine carboxyl meth...   186    9e-46
gi|328887289|emb|CCA60528.1|  hypothetical protein SVEN_7242 [Str...   180    5e-44
gi|320012403|gb|ADW07253.1|  Isoprenylcysteine carboxyl methyltra...   172    2e-41
gi|88854528|ref|ZP_01129195.1|  hypothetical protein A20C1_09929 ...   165    2e-39
gi|310818529|ref|YP_003950887.1|  hypothetical protein STAUR_1256...   164    5e-39
gi|115372824|ref|ZP_01460129.1|  isoprenylcysteine carboxyl methy...   161    3e-38
gi|126650524|ref|ZP_01722747.1|  hypothetical protein BB14905_080...   155    1e-36
gi|338532316|ref|YP_004665650.1|  hypothetical protein LILAB_1332...   155    2e-36
gi|108760951|ref|YP_634755.1|  hypothetical protein MXAN_6638 [My...   155    2e-36


>gi|15608279|ref|NP_215655.1| hypothetical protein Rv1139c [Mycobacterium tuberculosis H37Rv]
 gi|31792334|ref|NP_854827.1| hypothetical protein Mb1171c [Mycobacterium bovis AF2122/97]
 gi|121637072|ref|YP_977295.1| hypothetical protein BCG_1201c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 72 more sequence titles
 Length=166

 Score =  327 bits (838),  Expect = 3e-88, Method: Compositional matrix adjust.
 Identities = 165/166 (99%), Positives = 166/166 (100%), Gaps = 0/166 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA
Sbjct  1    MYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN
Sbjct  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI
Sbjct  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166


>gi|289442570|ref|ZP_06432314.1| conserved membrane protein [Mycobacterium tuberculosis T46]
 gi|289569136|ref|ZP_06449363.1| conserved membrane protein [Mycobacterium tuberculosis T17]
 gi|289415489|gb|EFD12729.1| conserved membrane protein [Mycobacterium tuberculosis T46]
 gi|289542890|gb|EFD46538.1| conserved membrane protein [Mycobacterium tuberculosis T17]
Length=166

 Score =  326 bits (835),  Expect = 9e-88, Method: Compositional matrix adjust.
 Identities = 164/166 (99%), Positives = 165/166 (99%), Gaps = 0/166 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA
Sbjct  1    MYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN
Sbjct  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVVAEGFALPLVHTAWLT LVFTLANATLLTVRLRVENSVLGYI
Sbjct  121  YVAVVAEGFALPLVHTAWLTTLVFTLANATLLTVRLRVENSVLGYI  166


>gi|340626153|ref|YP_004744605.1| hypothetical protein MCAN_11501 [Mycobacterium canettii CIPT 
140010059]
 gi|340004343|emb|CCC43486.1| conserved hypothetical membrane protein [Mycobacterium canettii 
CIPT 140010059]
Length=166

 Score =  325 bits (833),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 164/166 (99%), Positives = 165/166 (99%), Gaps = 0/166 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA
Sbjct  1    MYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN
Sbjct  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVVAEGFALPLVHTAWLTALVFTLANA LLTVRLRVENSVLGYI
Sbjct  121  YVAVVAEGFALPLVHTAWLTALVFTLANAILLTVRLRVENSVLGYI  166


>gi|240172487|ref|ZP_04751146.1| hypothetical protein MkanA1_24445 [Mycobacterium kansasii ATCC 
12478]
Length=166

 Score =  289 bits (740),  Expect = 8e-77, Method: Compositional matrix adjust.
 Identities = 143/165 (87%), Positives = 154/165 (94%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLL+LAV  ERLAEL+VA+RNARWSFAQGGKEFGRPHYVVMV LHTALLLGC+VEPWA
Sbjct  1    MYYLLVLAVGVERLAELIVARRNARWSFAQGGKEFGRPHYVVMVTLHTALLLGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFIPWLGWPM+ V++ SQGLRWWCVKSLG+RWNTRVIVLPH  LVRRGPYR M HPN
Sbjct  61   LHRPFIPWLGWPMVGVLLLSQGLRWWCVKSLGRRWNTRVIVLPHEPLVRRGPYRLMHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEGFALP+VHTAWLTAL FT+ANA LLTVRLRVENSVLGY
Sbjct  121  YVAVVAEGFALPMVHTAWLTALGFTVANAMLLTVRLRVENSVLGY  165


>gi|183984284|ref|YP_001852575.1| hypothetical protein MMAR_4314 [Mycobacterium marinum M]
 gi|183177610|gb|ACC42720.1| conserved hypothetical membrane protein [Mycobacterium marinum 
M]
Length=169

 Score =  286 bits (733),  Expect = 5e-76, Method: Compositional matrix adjust.
 Identities = 138/164 (85%), Positives = 154/164 (94%), Gaps = 0/164 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YYLLILA+V ERLAELV+AQRNARWSFAQGGKEFG+PHYVVMV+LH+ LL+GCV+EPWAL
Sbjct  5    YYLLILAIVVERLAELVIAQRNARWSFAQGGKEFGQPHYVVMVVLHSLLLVGCVIEPWAL  64

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            HRPFIPWLGWPM+AV+V SQGLRWWCV SLG+RWNTRVIVLP   LV++GPYR++ HPNY
Sbjct  65   HRPFIPWLGWPMVAVLVLSQGLRWWCVTSLGRRWNTRVIVLPDEPLVQKGPYRFLHHPNY  124

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            VAVVAEGFALPLVHTAW+TAL FT+ANA LLTVRLRVENSVLGY
Sbjct  125  VAVVAEGFALPLVHTAWVTALSFTVANAILLTVRLRVENSVLGY  168


>gi|118616734|ref|YP_905066.1| hypothetical protein MUL_0980 [Mycobacterium ulcerans Agy99]
 gi|118568844|gb|ABL03595.1| conserved hypothetical membrane protein [Mycobacterium ulcerans 
Agy99]
Length=169

 Score =  283 bits (723),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 136/164 (83%), Positives = 153/164 (94%), Gaps = 0/164 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YYLLILA+V ERLAELV+AQRNARWSFAQGGKEFG+PHYVVMV+LH+ LL+GCV+EPWAL
Sbjct  5    YYLLILAIVVERLAELVIAQRNARWSFAQGGKEFGQPHYVVMVVLHSLLLVGCVIEPWAL  64

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            +RPFIPWLGWPM+AV+V SQGLRWWCV SLG+RWNTRVIVLP   L ++GPYR++ HPNY
Sbjct  65   YRPFIPWLGWPMVAVLVLSQGLRWWCVTSLGRRWNTRVIVLPDEPLAQKGPYRFLHHPNY  124

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            VAVVAEGFALPLVHTAW+TAL FT+ANA LLTVRLRVENSVLGY
Sbjct  125  VAVVAEGFALPLVHTAWVTALSFTVANAILLTVRLRVENSVLGY  168


>gi|254820704|ref|ZP_05225705.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium intracellulare ATCC 13950]
Length=166

 Score =  275 bits (702),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 133/165 (81%), Positives = 146/165 (89%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLL+LAV  ER+AELVV+ RNARWSF QG KEFGR HY VMV++HT LL+GC+VEPWA
Sbjct  1    MYYLLVLAVGVERVAELVVSTRNARWSFTQGAKEFGRSHYPVMVVIHTGLLVGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFIPWLGWPMLAVV ASQ LRWWC+ +LG+RWNTRVIVLP A LVRRGPYRW+ HPN
Sbjct  61   LHRPFIPWLGWPMLAVVAASQALRWWCITTLGRRWNTRVIVLPQAPLVRRGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA +FTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAIFTLANAALLGVRLRVENSALGY  165


>gi|118464098|ref|YP_880524.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium avium 104]
 gi|118165385|gb|ABK66282.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium avium 104]
Length=166

 Score =  272 bits (695),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 133/165 (81%), Positives = 145/165 (88%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLL+LAV  ER+AEL+V+ RNARWSF QGGKEFGR HY VMV +HTALL GC+VEPWA
Sbjct  1    MYYLLVLAVGLERVAELLVSTRNARWSFTQGGKEFGRSHYPVMVFIHTALLAGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPF+ WLGWPMLAVV ASQGLRWWC+ +LG+RWNTRVIVLP A LVR GPYRW+ HPN
Sbjct  61   LHRPFLGWLGWPMLAVVAASQGLRWWCITTLGRRWNTRVIVLPQAPLVRDGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA VFTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAVFTLANAALLRVRLRVENSALGY  165


>gi|254774155|ref|ZP_05215671.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium avium subsp. avium ATCC 25291]
Length=166

 Score =  270 bits (691),  Expect = 4e-71, Method: Compositional matrix adjust.
 Identities = 132/165 (80%), Positives = 144/165 (88%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLL+L V  ER+AEL+V+ RNARWSF QGGKEFGR HY VMV +HTALL GC+VEPWA
Sbjct  1    MYYLLVLTVGLERVAELLVSTRNARWSFTQGGKEFGRSHYPVMVFIHTALLAGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPF+ WLGWPMLAVV ASQGLRWWC+ +LG+RWNTRVIVLP A LVR GPYRW+ HPN
Sbjct  61   LHRPFLGWLGWPMLAVVAASQGLRWWCITTLGRRWNTRVIVLPQAPLVRDGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA VFTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAVFTLANAALLRVRLRVENSALGY  165


>gi|296170027|ref|ZP_06851631.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295895295|gb|EFG75004.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=166

 Score =  270 bits (689),  Expect = 7e-71, Method: Compositional matrix adjust.
 Identities = 132/165 (80%), Positives = 145/165 (88%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLLILAV  ER+ ELVV++RNARWSFAQG KEFGR HY VMV+LHT LL+GC+VEPWA
Sbjct  1    MYYLLILAVGIERVVELVVSRRNARWSFAQGAKEFGRAHYPVMVVLHTGLLVGCIVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPFI WLGWPMLAVV  SQGLRWWC+ +LG+RWNTRVIVLP A LVR+GPYRW+ HPN
Sbjct  61   LHRPFIAWLGWPMLAVVALSQGLRWWCIATLGRRWNTRVIVLPQAPLVRQGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA +FTLAN  LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAIFTLANLALLRVRLRVENSALGY  165


>gi|336458769|gb|EGO37729.1| hypothetical protein MAPs_10530 [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=166

 Score =  268 bits (686),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 132/165 (80%), Positives = 144/165 (88%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +Y LL+LAV  ER+AEL+V+ RNARWSF QGGKEFGR HY VMV +HTALL GC+VEPWA
Sbjct  1    MYCLLVLAVGLERVAELLVSTRNARWSFTQGGKEFGRSHYPVMVFIHTALLAGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPF+ WLGWPMLAVV ASQGLRWWC+ +LG+RWNTRVIVLP A LVR GPYRW+ HPN
Sbjct  61   LHRPFLGWLGWPMLAVVAASQGLRWWCITTLGRRWNTRVIVLPQAPLVRDGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA VFTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAVFTLANAALLRVRLRVENSALGY  165


>gi|41408741|ref|NP_961577.1| hypothetical protein MAP2643 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397099|gb|AAS04960.1| hypothetical protein MAP_2643 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=166

 Score =  266 bits (681),  Expect = 6e-70, Method: Compositional matrix adjust.
 Identities = 131/165 (80%), Positives = 143/165 (87%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +Y LL+LAV  ER+AEL+V+ RNARWSF QGGKEFGR HY VMV + TALL GC+VEPWA
Sbjct  1    MYCLLVLAVGLERVAELLVSTRNARWSFTQGGKEFGRSHYPVMVFIQTALLAGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            LHRPF+ WLGWPMLAVV ASQGLRWWC+ +LG+RWNTRVIVLP A LVR GPYRW+ HPN
Sbjct  61   LHRPFLGWLGWPMLAVVAASQGLRWWCITTLGRRWNTRVIVLPQAPLVRDGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA VFTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTAAVFTLANAALLRVRLRVENSALGY  165


>gi|342861751|ref|ZP_08718397.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium colombiense CECT 3035]
 gi|342130885|gb|EGT84181.1| isoprenylcysteine carboxyl methyltransferase (icmt) family protein 
[Mycobacterium colombiense CECT 3035]
Length=166

 Score =  264 bits (675),  Expect = 3e-69, Method: Compositional matrix adjust.
 Identities = 130/165 (79%), Positives = 143/165 (87%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYLL+LAV  ER+ ELVV+ RNARWSF +G  EFGR HY VMVI+HT LL+GC+VEPWA
Sbjct  1    MYYLLVLAVGLERVVELVVSTRNARWSFTKGATEFGRSHYPVMVIIHTGLLVGCLVEPWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            L RPFI WLGWPMLAVVVASQ LRWWC+ +LG+RWNTRVIVLP A LVR+GPYRW+ HPN
Sbjct  61   LDRPFIGWLGWPMLAVVVASQALRWWCIATLGRRWNTRVIVLPRAPLVRQGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAVVAEG ALPLVHTAWLTA VFTLANA LL VRLRVENS LGY
Sbjct  121  YVAVVAEGLALPLVHTAWLTATVFTLANAALLRVRLRVENSALGY  165


>gi|15840579|ref|NP_335616.1| hypothetical protein MT1172 [Mycobacterium tuberculosis CDC1551]
 gi|13880758|gb|AAK45430.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
Length=124

 Score =  245 bits (626),  Expect = 1e-63, Method: Compositional matrix adjust.
 Identities = 124/124 (100%), Positives = 124/124 (100%), Gaps = 0/124 (0%)

Query  43   MVILHTALLLGCVVEPWALHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVL  102
            MVILHTALLLGCVVEPWALHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVL
Sbjct  1    MVILHTALLLGCVVEPWALHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVL  60

Query  103  PHATLVRRGPYRWMRHPNYVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSV  162
            PHATLVRRGPYRWMRHPNYVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSV
Sbjct  61   PHATLVRRGPYRWMRHPNYVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSV  120

Query  163  LGYI  166
            LGYI
Sbjct  121  LGYI  124


>gi|333990401|ref|YP_004523015.1| hypothetical protein JDM601_1761 [Mycobacterium sp. JDM601]
 gi|333486369|gb|AEF35761.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=166

 Score =  232 bits (591),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 113/165 (69%), Positives = 136/165 (83%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +Y LLI+AV  ERL EL+V++RNA W+F+ GG+E+GR HY VMV+LH ALL GC++E WA
Sbjct  1    MYTLLIVAVGIERLVELLVSRRNAGWAFSHGGEEYGRGHYPVMVVLHGALLAGCLIEVWA  60

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
             HR FIP LGWPMLAVV A Q LRWWC+ +LG RWNTRVIV+P+A LVR GPYRW+ HPN
Sbjct  61   AHRVFIPRLGWPMLAVVAAGQALRWWCIGTLGPRWNTRVIVIPNAPLVRAGPYRWLHHPN  120

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            YVAV+ EG ALPLVH+AWLTA+ F +ANA LL VR+RVEN+ LGY
Sbjct  121  YVAVMVEGLALPLVHSAWLTAIGFGVANALLLVVRIRVENTALGY  165


>gi|342861400|ref|ZP_08718048.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium colombiense 
CECT 3035]
 gi|342131300|gb|EGT84581.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium colombiense 
CECT 3035]
Length=167

 Score =  216 bits (549),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 112/164 (69%), Positives = 128/164 (79%), Gaps = 0/164 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YYL ILAV  ERL EL VA+RNARWS A GGKEFGR HY  MV +H  LL+ C+VE W+L
Sbjct  3    YYLFILAVGAERLVELAVARRNARWSMAHGGKEFGRDHYPAMVSMHGLLLVSCIVETWSL  62

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPFI WLGWPMLAVV  S  +RW CV  LGK WN R+IV+P A LVRRGPYRW+RHPNY
Sbjct  63   GRPFIGWLGWPMLAVVALSTVVRWRCVSVLGKHWNPRLIVIPDAPLVRRGPYRWVRHPNY  122

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
             AV AE  ALPLVH+AWLTA++F+LANA +L VR+R EN+ LGY
Sbjct  123  AAVAAEVAALPLVHSAWLTAIMFSLANALVLAVRIRAENAALGY  166


>gi|256391299|ref|YP_003112863.1| isoprenylcysteine carboxyl methyltransferase [Catenulispora acidiphila 
DSM 44928]
 gi|256357525|gb|ACU71022.1| Isoprenylcysteine carboxyl methyltransferase [Catenulispora acidiphila 
DSM 44928]
Length=169

 Score =  214 bits (546),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 107/158 (68%), Positives = 121/158 (77%), Gaps = 0/158 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YY L++A   ERLAELVVA+RNA WS A+GG E GR HY  MV+LHT LL GC+VEP   
Sbjct  4    YYALVIATCCERLAELVVAKRNAAWSLARGGVETGRGHYPPMVLLHTGLLAGCLVEPVVA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            HR F+P LG PML + V SQGLRWWC+K+LG RWNTRVIV+P   LV  GPYRW  HPNY
Sbjct  64   HRTFVPALGIPMLVLAVGSQGLRWWCIKTLGPRWNTRVIVVPGLPLVDSGPYRWFAHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVE  159
            VAVV EGFALPL  +AW+TA VFT+ NA LLTVRLR E
Sbjct  124  VAVVVEGFALPLAGSAWVTAAVFTVLNAALLTVRLRCE  161


>gi|145225717|ref|YP_001136395.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium gilvum 
PYR-GCK]
 gi|315446068|ref|YP_004078947.1| hypothetical protein Mspyr1_45610 [Mycobacterium sp. Spyr1]
 gi|145218203|gb|ABP47607.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium gilvum 
PYR-GCK]
 gi|315264371|gb|ADU01113.1| uncharacterized conserved protein [Mycobacterium sp. Spyr1]
Length=170

 Score =  214 bits (546),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 109/162 (68%), Positives = 127/162 (79%), Gaps = 2/162 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LLI AV  ERLAELVV+QRN +WS A+GG EFG  HY VMV+LHTALL+GC+VE  A 
Sbjct  4    YTLLIAAVAVERLAELVVSQRNLKWSKARGGVEFGAGHYPVMVVLHTALLVGCLVE--AS  61

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            HR FIP LGW M AV +A+Q LRWWC+ +LG +WNTRV+V+P+A  V  GPYR+M HPNY
Sbjct  62   HREFIPALGWTMFAVAIAAQALRWWCITTLGPQWNTRVVVVPNAGRVTGGPYRFMSHPNY  121

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAVV EG ALPLVHTAW+TALVFT+ NA LL  R+ VEN  L
Sbjct  122  VAVVVEGIALPLVHTAWITALVFTVLNAALLWTRISVENKAL  163


>gi|311895218|dbj|BAJ27626.1| putative methyltransferase [Kitasatospora setae KM-6054]
Length=173

 Score =  211 bits (537),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 105/162 (65%), Positives = 125/162 (78%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y +LI  V  ERLAEL+VA+RNA WS A+GG E GR HY  MV+LHTALL GC++E    
Sbjct  4    YTVLIALVAAERLAELLVARRNAAWSLARGGVEHGRGHYPAMVLLHTALLAGCLLEVHYA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+P LGWPMLA+ + +QGLRWWC+++LG RWNTRVIV+P   LV  GPYRW+RHPNY
Sbjct  64   QRPFVPRLGWPMLALALGAQGLRWWCIRTLGPRWNTRVIVVPGLPLVSGGPYRWLRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            +AVV EGFALPLVHTAW TAL FTL +  LL  RLR E++ L
Sbjct  124  LAVVVEGFALPLVHTAWATALCFTLLDGWLLATRLRCEDAAL  165


>gi|108799296|ref|YP_639493.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
MCS]
 gi|119868412|ref|YP_938364.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
KMS]
 gi|126434953|ref|YP_001070644.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
JLS]
 gi|108769715|gb|ABG08437.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
MCS]
 gi|119694501|gb|ABL91574.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
KMS]
 gi|126234753|gb|ABN98153.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
JLS]
Length=184

 Score =  211 bits (536),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 109/165 (67%), Positives = 131/165 (80%), Gaps = 0/165 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +YYL I+AV  ER+ ELVVA+R+ RWS A GG+EFGR HY +MV +HT LL+ CVVE   
Sbjct  5    IYYLFIVAVGVERVLELVVARRHTRWSIANGGREFGRGHYPLMVTMHTLLLVSCVVEVSV  64

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
             HRPFIPWLGW M+AVVVAS  +RWWCV  LG  WN R+IV+P A LVRRGPYRW+ HPN
Sbjct  65   AHRPFIPWLGWTMVAVVVASTVVRWWCVSVLGNHWNPRLIVIPGAPLVRRGPYRWVHHPN  124

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGY  165
            Y+AV AE  ALPL+H+AW+TA+VFT+ANA +LTVR+R EN  LGY
Sbjct  125  YIAVAAEVAALPLIHSAWVTAIVFTIANALVLTVRIRAENVALGY  169


>gi|126433694|ref|YP_001069385.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
JLS]
 gi|126233494|gb|ABN96894.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
JLS]
Length=169

 Score =  210 bits (535),  Expect = 5e-53, Method: Compositional matrix adjust.
 Identities = 107/162 (67%), Positives = 127/162 (79%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LLI AV  ERL ELVVA+RN RWS  +GG E+G  HY VMV+LHT LL GC++E  AL
Sbjct  4    YGLLIAAVGVERLGELVVAERNRRWSRQRGGVEYGARHYPVMVVLHTGLLAGCLLEVAAL  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF P LG+PMLA+V+A+Q LRWWC+ +LG++WNTRVIV+P A+ V  GPYR + HPNY
Sbjct  64   KRPFTPVLGFPMLALVIAAQALRWWCITTLGRQWNTRVIVVPGASRVTGGPYRLIPHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAVV EGFALPLVH AW+TALVFT  NA LL  R+RVEN+ L
Sbjct  124  VAVVVEGFALPLVHGAWITALVFTALNAALLRTRVRVENAAL  165


>gi|296164684|ref|ZP_06847250.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295899992|gb|EFG79432.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=173

 Score =  210 bits (534),  Expect = 6e-53, Method: Compositional matrix adjust.
 Identities = 107/163 (66%), Positives = 125/163 (77%), Gaps = 0/163 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YYL ILA+  ERL EL V++RN +WS AQGGKEFGR HY  MV +H  LL+ CVVE  A 
Sbjct  9    YYLFILAIAAERLVELAVSRRNTKWSLAQGGKEFGRDHYPAMVCMHALLLVSCVVETRAF  68

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+PWLGWPMLAVV  S  +RW CV  LGKRWN R+IV+P A LVR G YRW+RHPNY
Sbjct  69   ARPFVPWLGWPMLAVVALSTAVRWRCVSVLGKRWNPRLIVIPGAPLVRDGLYRWVRHPNY  128

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLG  164
             AV AE  ALPLVH+AWLTA+VF++ANA +L VR+R EN+ LG
Sbjct  129  AAVAAEVAALPLVHSAWLTAIVFSVANALVLNVRIRAENAALG  171


>gi|108798033|ref|YP_638230.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
MCS]
 gi|119867128|ref|YP_937080.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
KMS]
 gi|108768452|gb|ABG07174.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
MCS]
 gi|119693217|gb|ABL90290.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium sp. 
KMS]
Length=169

 Score =  209 bits (532),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 108/162 (67%), Positives = 127/162 (79%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LLI AV  ERL ELVVA+RN RWS  +GG E+G  HY VMV+LHT LL GC++E  AL
Sbjct  4    YGLLIAAVGVERLGELVVAERNRRWSRQRGGIEYGARHYPVMVVLHTGLLAGCLLEVAAL  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            HRPF P LG+PMLA+V+A+Q LRWWC+ +LG +WNTRVIV+P A+ V  GPYR + HPNY
Sbjct  64   HRPFTPVLGFPMLALVIAAQALRWWCITTLGWQWNTRVIVVPGASRVTGGPYRLIPHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAVV EGFALPLVH AW+TALVFT  NA LL  R+RVEN+ L
Sbjct  124  VAVVVEGFALPLVHGAWITALVFTALNAALLRTRVRVENAAL  165


>gi|317126612|ref|YP_004100724.1| isoprenylcysteine carboxyl methyltransferase [Intrasporangium 
calvum DSM 43043]
 gi|315590700|gb|ADU49997.1| Isoprenylcysteine carboxyl methyltransferase [Intrasporangium 
calvum DSM 43043]
Length=177

 Score =  208 bits (529),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 102/159 (65%), Positives = 125/159 (79%), Gaps = 0/159 (0%)

Query  5    LILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRP  64
            L+L V  ER+AEL+V+ R+A W+F++G  E G+ HY VMV+LH+ALL+G V E W   RP
Sbjct  12   LVLLVGLERVAELIVSNRHASWAFSRGAVERGQGHYPVMVVLHSALLVGAVAEAWLTDRP  71

Query  65   FIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNYVAV  124
            F+P LGW ML + + SQ LRWWC+ +LG +WNTRVIV+P   LVRRGPYR++ HPNYVAV
Sbjct  72   FLPALGWTMLVIALGSQALRWWCILTLGNQWNTRVIVVPGLPLVRRGPYRFLPHPNYVAV  131

Query  125  VAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAEG ALPLVHTAW+TA VFTLANA LLT R+RVEN  L
Sbjct  132  VAEGLALPLVHTAWVTATVFTLANALLLTQRIRVENDAL  170


>gi|297190133|ref|ZP_06907531.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces pristinaespiralis 
ATCC 25486]
 gi|197721152|gb|EDY65060.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces pristinaespiralis 
ATCC 25486]
Length=171

 Score =  208 bits (529),  Expect = 3e-52, Method: Compositional matrix adjust.
 Identities = 107/163 (66%), Positives = 127/163 (78%), Gaps = 0/163 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y +L+LAV  ER+AELVVA+RNA W+ A+ G E GR HY VMV LHTALL+GC+VE    
Sbjct  4    YTVLVLAVAAERVAELVVARRNAAWTLARAGVEHGRGHYPVMVALHTALLVGCLVEVAIG  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+P LGW ML VVV +Q LRWWC+ +LG  WNTRVIV+P A LVR GPYR+ RHPNY
Sbjct  64   DRPFVPALGWSMLGVVVLAQALRWWCILTLGPYWNTRVIVVPGARLVRAGPYRFARHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLG  164
            VAVVAE  ALPLVH+AWLTALV T++NA L+ VR+R EN+ L 
Sbjct  124  VAVVAEIAALPLVHSAWLTALVLTVSNAVLMGVRVRCENTALA  166


>gi|120402207|ref|YP_952036.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium vanbaalenii 
PYR-1]
 gi|119955025|gb|ABM12030.1| Isoprenylcysteine carboxyl methyltransferase [Mycobacterium vanbaalenii 
PYR-1]
Length=168

 Score =  206 bits (525),  Expect = 6e-52, Method: Compositional matrix adjust.
 Identities = 106/162 (66%), Positives = 125/162 (78%), Gaps = 2/162 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LLI AV  ER+AELVV+QRN RWS A+GG EFG  HY +MV+LHT LL  C+VE  A 
Sbjct  4    YTLLIAAVALERVAELVVSQRNLRWSRARGGVEFGATHYPLMVLLHTVLLAACLVE--AA  61

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
            HR FIP LGW M A+VVA+QGLRWWC+ +LG +WNTRV+V+P A  V  GPYR++ HPNY
Sbjct  62   HREFIPVLGWSMFALVVAAQGLRWWCITTLGHQWNTRVVVVPGAGRVTGGPYRFLSHPNY  121

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAVV EG ALPLVHTAW+TAL FTL NA LL +R+ VE+  L
Sbjct  122  VAVVVEGIALPLVHTAWVTALAFTLLNAALLWMRISVEDKAL  163


>gi|182434264|ref|YP_001821983.1| methyltransferase [Streptomyces griseus subsp. griseus NBRC 13350]
 gi|178462780|dbj|BAG17300.1| methyltransferase [Streptomyces griseus subsp. griseus NBRC 13350]
Length=177

 Score =  206 bits (525),  Expect = 6e-52, Method: Compositional matrix adjust.
 Identities = 106/162 (66%), Positives = 119/162 (74%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+LAV  ERLAELVVA+RN RWS A+GG E GR HY  MV LHT LLLGC+ E    
Sbjct  6    YTLLVLAVAAERLAELVVARRNTRWSLARGGVESGRGHYPAMVALHTGLLLGCLAEVRFA  65

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF   LGW M  VVVASQ LRWWC+++LG RWNTRVIV+P    V  GPYRW+ HPNY
Sbjct  66   ERPFPAVLGWTMAGVVVASQALRWWCIRTLGPRWNTRVIVVPGLPRVTGGPYRWLSHPNY  125

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAV AEG ALPLVH AW+TALVFT  NA L+ VR+R E+  L
Sbjct  126  VAVAAEGIALPLVHGAWVTALVFTALNAALMVVRIRCEDGAL  167


>gi|284030487|ref|YP_003380418.1| Isoprenylcysteine carboxyl methyltransferase [Kribbella flavida 
DSM 17836]
 gi|283809780|gb|ADB31619.1| Isoprenylcysteine carboxyl methyltransferase [Kribbella flavida 
DSM 17836]
Length=175

 Score =  206 bits (524),  Expect = 8e-52, Method: Compositional matrix adjust.
 Identities = 101/152 (67%), Positives = 121/152 (80%), Gaps = 0/152 (0%)

Query  12   ERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRPFIPWLGW  71
            ER+AELVV+ RNA+WSFAQGG E G+ HY  MV+LHT LL GC+VE     RPF+P LGW
Sbjct  18   ERVAELVVSLRNAKWSFAQGGVESGKGHYPFMVVLHTGLLAGCLVEAIVADRPFVPELGW  77

Query  72   PMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNYVAVVAEGFAL  131
             MLAVVV +QGLRWWC+  LG++WNTRVIV+P  +LV  GPYRW+RHPNYVAVV EG AL
Sbjct  78   TMLAVVVLAQGLRWWCITVLGRQWNTRVIVVPGLSLVAGGPYRWIRHPNYVAVVLEGVAL  137

Query  132  PLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            PLVHT+W+TA+VFT+ N  LL VR+R E + L
Sbjct  138  PLVHTSWVTAVVFTVLNLPLLAVRIRAEEAAL  169


>gi|326774777|ref|ZP_08234042.1| Isoprenylcysteine carboxyl methyltransferase [Streptomyces cf. 
griseus XylebKG-1]
 gi|326655110|gb|EGE39956.1| Isoprenylcysteine carboxyl methyltransferase [Streptomyces griseus 
XylebKG-1]
Length=177

 Score =  205 bits (522),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 105/162 (65%), Positives = 120/162 (75%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+LAV  ERLAELVVA+RN RWS A+GG E GR HY  MV+LHT LLLGC+ E    
Sbjct  6    YTLLVLAVAAERLAELVVARRNTRWSLARGGVESGRGHYPAMVVLHTGLLLGCLAEVRFA  65

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF   LGW M  VVVASQ LRWWC+++LG RWNTRVIV+P    V  GPYRW+ HPNY
Sbjct  66   ERPFPAVLGWTMAGVVVASQALRWWCIRTLGPRWNTRVIVVPGLPRVTGGPYRWLSHPNY  125

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAV AEG ALPLV+ AW+TALVFT  NA L+ VR+R E+  L
Sbjct  126  VAVAAEGIALPLVYGAWVTALVFTALNAALMVVRIRCEDGAL  167


>gi|336322079|ref|YP_004602047.1| Isoprenylcysteine carboxyl methyltransferase [Cellvibrio gilvus 
ATCC 13127]
 gi|336105660|gb|AEI13479.1| Isoprenylcysteine carboxyl methyltransferase [Cellvibrio gilvus 
ATCC 13127]
Length=174

 Score =  204 bits (518),  Expect = 4e-51, Method: Compositional matrix adjust.
 Identities = 101/152 (67%), Positives = 119/152 (79%), Gaps = 0/152 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            +Y  L++A   ERLAELVV+ R+ARWSFA+GG+E GR H+  MV LHT LL+ CV E   
Sbjct  5    LYVALVVATGLERLAELVVSARHARWSFARGGRESGRGHFPAMVALHTGLLVACVAEAVL  64

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
              RPF+PWLGWP L VV+ASQ LRWWC++ LG +WNTRVIV+P   LV RGPYR +RHPN
Sbjct  65   ADRPFLPWLGWPALVVVLASQALRWWCIRVLGPQWNTRVIVVPGLGLVARGPYRLLRHPN  124

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLL  152
            YVAVVAEG ALPLVHTAW+TAL FT+ NA LL
Sbjct  125  YVAVVAEGVALPLVHTAWVTALAFTVLNAVLL  156


>gi|297201166|ref|ZP_06918563.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces sviceus 
ATCC 29083]
 gi|197713716|gb|EDY57750.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces sviceus 
ATCC 29083]
Length=175

 Score =  199 bits (507),  Expect = 9e-50, Method: Compositional matrix adjust.
 Identities = 102/157 (65%), Positives = 117/157 (75%), Gaps = 2/157 (1%)

Query  6    ILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRPF  65
            +  V  ER+AELVVA+RN RWS A+G  E G+ HY  MV LHT LL  C  E W   RPF
Sbjct  1    MAGVAAERVAELVVARRNERWSTARGATETGQGHYPAMVALHTGLLAACPAEVWLGDRPF  60

Query  66   IPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPY--RWMRHPNYVA  123
            +P L WPMLAV+  +Q LRWWC+ +LG RWNTRVIV+P   LV RGPY  RW+RHPNYVA
Sbjct  61   VPVLAWPMLAVLAGAQALRWWCIHTLGPRWNTRVIVVPGLPLVARGPYRWRWLRHPNYVA  120

Query  124  VVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVEN  160
            VVAEG ALPLVHTAW+TA VFT+ NA LLTVR+R EN
Sbjct  121  VVAEGLALPLVHTAWITATVFTVLNAALLTVRIRCEN  157


>gi|271967232|ref|YP_003341428.1| hypothetical protein Sros_5950 [Streptosporangium roseum DSM 
43021]
 gi|270510407|gb|ACZ88685.1| conserved hypothetical protein [Streptosporangium roseum DSM 
43021]
Length=186

 Score =  197 bits (502),  Expect = 4e-49, Method: Compositional matrix adjust.
 Identities = 103/167 (62%), Positives = 124/167 (75%), Gaps = 2/167 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+L V  ERLAELVVA+RNARWS A+GG   G+ HY  MV LHT LL GC++E    
Sbjct  9    YLLLVLLVGAERLAELVVARRNARWSAARGGVVSGQGHYPWMVALHTGLLAGCLLEAGLA  68

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYR--WMRHP  119
             RPF+P LGWPML +VVA+QGLRWWC+ +LG RWNT+VIV+P    V RGPYR  W+RHP
Sbjct  69   GRPFVPALGWPMLVLVVAAQGLRWWCIAALGHRWNTQVIVVPGLPPVTRGPYRLHWLRHP  128

Query  120  NYVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            NYVAV  EG ALPLVH AW+TA+ FT+ NA L+ VR+R E + L  +
Sbjct  129  NYVAVAVEGAALPLVHGAWITAVTFTVLNAALMVVRIRCEETALASL  175


>gi|296129012|ref|YP_003636262.1| Isoprenylcysteine carboxyl methyltransferase [Cellulomonas flavigena 
DSM 20109]
 gi|296020827|gb|ADG74063.1| Isoprenylcysteine carboxyl methyltransferase [Cellulomonas flavigena 
DSM 20109]
Length=172

 Score =  196 bits (498),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 107/157 (69%), Positives = 124/157 (79%), Gaps = 2/157 (1%)

Query  3    YLLILAVV-FERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            YL ++A+   ERLAELVV+ RNARWSFA+GG E GR H+  MV LHTALL+ CVVE    
Sbjct  5    YLTVVALTAVERLAELVVSARNARWSFARGGVETGRGHFPAMVALHTALLVACVVEVVVA  64

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+PWLGWP LA+VVASQ LRWWC+ +LG RWNTRVIV+P   LV  GPYRW+RHPNY
Sbjct  65   DRPFLPWLGWPALALVVASQALRWWCIGTLGPRWNTRVIVVPDLPLVGGGPYRWLRHPNY  124

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRV  158
            VAVV EG ALPLVHTAW+TAL FT+ NA LL +R R+
Sbjct  125  VAVVLEGIALPLVHTAWVTALAFTVLNAVLL-LRFRI  160


>gi|289766907|ref|ZP_06526285.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces lividans 
TK24]
 gi|289697106|gb|EFD64535.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces lividans 
TK24]
Length=171

 Score =  193 bits (491),  Expect = 6e-48, Method: Compositional matrix adjust.
 Identities = 104/165 (64%), Positives = 124/165 (76%), Gaps = 0/165 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+LAV  ER+AELVVA+RNA W+ A+ G E GR HY VMV LHT LL  C++EP   
Sbjct  4    YALLVLAVAVERVAELVVARRNAAWTLARAGVEHGRGHYPVMVALHTGLLACCLLEPLLA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+P LGWPMLA+ + +Q LRWWC+ +LG  WNTRVIV+P    V  GPYR++RHPNY
Sbjct  64   DRPFLPALGWPMLALALLAQALRWWCIATLGPYWNTRVIVVPGTRPVGAGPYRFLRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            +AVV E  ALPLVH+AWLTA VFT ANA LLTVRLR EN+ L  +
Sbjct  124  LAVVVEVAALPLVHSAWLTAAVFTAANAMLLTVRLRCENTALAQL  168


>gi|118467589|ref|YP_885213.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium smegmatis 
str. MC2 155]
 gi|118168876|gb|ABK69772.1| isoprenylcysteine carboxyl methyltransferase [Mycobacterium smegmatis 
str. MC2 155]
Length=167

 Score =  193 bits (490),  Expect = 8e-48, Method: Compositional matrix adjust.
 Identities = 103/162 (64%), Positives = 118/162 (73%), Gaps = 2/162 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            +  L+ AV  ERLAELVV++RN  WS   GGKEFG  HY VMV LHT LL G  +E  A 
Sbjct  4    FTALVAAVAAERLAELVVSKRNLEWSKTHGGKEFGAGHYPVMVALHTGLLAGAALE--AR  61

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             R   P LG PM AVV+A+QGLRWWC+K+LG +WNTRVIV+P AT V  GPYR++ HPNY
Sbjct  62   RRRVRPALGRPMFAVVLAAQGLRWWCIKTLGPQWNTRVIVVPGATRVLAGPYRFLPHPNY  121

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            VAVVAEG ALPLV  AW TAL FT+ANA LL  R+RVEN  L
Sbjct  122  VAVVAEGVALPLVGGAWRTALGFTIANALLLRTRIRVENDAL  163


>gi|291435054|ref|ZP_06574444.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces ghanaensis 
ATCC 14672]
 gi|291337949|gb|EFE64905.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces ghanaensis 
ATCC 14672]
Length=172

 Score =  192 bits (489),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 96/163 (59%), Positives = 120/163 (74%), Gaps = 0/163 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            ++ +L+ AV  ER+AEL V+ RNA WS A+GG EFGR HY  MV+LHT LL+G +VE W 
Sbjct  6    LFTVLVSAVGLERVAELAVSHRNAGWSLARGGVEFGRDHYPFMVVLHTGLLVGALVEVWV  65

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
                 +P L W MLA+V ASQ LRWWC+ +LG++WNTRVIV+P A  V  GPYR + HPN
Sbjct  66   RRPDVVPVLAWAMLALVAASQVLRWWCIATLGRQWNTRVIVVPGAPRVTGGPYRRLSHPN  125

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            YVAVV EG ALPLVH+AW+TA+VFT+ N  LL  R+R EN+ L
Sbjct  126  YVAVVVEGLALPLVHSAWVTAVVFTVLNGFLLATRIRTENTAL  168


>gi|296269923|ref|YP_003652555.1| Isoprenylcysteine carboxyl methyltransferase [Thermobispora bispora 
DSM 43833]
 gi|296092710|gb|ADG88662.1| Isoprenylcysteine carboxyl methyltransferase [Thermobispora bispora 
DSM 43833]
Length=189

 Score =  192 bits (488),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 100/159 (63%), Positives = 116/159 (73%), Gaps = 0/159 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+ AV  ERLAEL V++RNARWS A+GG   GR HY +MV LH  LL GC++E    
Sbjct  5    YALLVAAVGAERLAELAVSRRNARWSLARGGVVTGRGHYPLMVALHAGLLAGCLLEVRLA  64

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             R F P LGWPML + +A+Q LRWWCV++LG RWNT+VIV+P   LV  GPYR MRHPNY
Sbjct  65   RRRFRPALGWPMLGLTLAAQALRWWCVRTLGPRWNTQVIVVPGMPLVTAGPYRVMRHPNY  124

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVEN  160
            +AV  EG ALPLVH AWLTA  FTL NA LL VR+R EN
Sbjct  125  LAVAVEGAALPLVHGAWLTAAAFTLLNAPLLAVRIRCEN  163


>gi|334337018|ref|YP_004542170.1| Isoprenylcysteine carboxyl methyltransferase [Isoptericola variabilis 
225]
 gi|334107386|gb|AEG44276.1| Isoprenylcysteine carboxyl methyltransferase [Isoptericola variabilis 
225]
Length=173

 Score =  192 bits (487),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 102/151 (68%), Positives = 114/151 (76%), Gaps = 0/151 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y  L+ A   ERLAELVV+ RNARW+FA+GG E GR HY  MV LHT LL+ CV E W  
Sbjct  4    YVALVAATALERLAELVVSTRNARWAFARGGVEHGRGHYPAMVALHTGLLVACVAEAWLA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+PWLGWPML VV+ASQ LRWWCV+SLG RWNTRV+V+P   LV RGPY   RHPNY
Sbjct  64   DRPFLPWLGWPMLVVVLASQALRWWCVRSLGPRWNTRVVVVPGLPLVVRGPYARWRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLL  152
            VAVV EG ALPLVHT W+TA  FT+ NA LL
Sbjct  124  VAVVLEGVALPLVHTCWITATAFTVLNAILL  154


>gi|239992518|ref|ZP_04713182.1| methyltransferase [Streptomyces roseosporus NRRL 11379]
 gi|291449497|ref|ZP_06588887.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces roseosporus 
NRRL 15998]
 gi|291352444|gb|EFE79348.1| isoprenylcysteine carboxyl methyltransferase [Streptomyces roseosporus 
NRRL 15998]
Length=175

 Score =  191 bits (486),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 104/165 (64%), Positives = 121/165 (74%), Gaps = 0/165 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y +L+LAV  ERLAELVVA+RN RWS A+GG E GR HY  MV LHTALL GC+ E    
Sbjct  4    YTVLVLAVAAERLAELVVARRNTRWSLARGGVESGREHYPAMVALHTALLAGCLAEVHLA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF P LGW M+A VVA+Q LRWWC+++LG RWNTRVIV+P    V  GPYRW+ HPNY
Sbjct  64   DRPFPPVLGWVMVAAVVAAQALRWWCIRTLGPRWNTRVIVVPGLPRVTGGPYRWLSHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            VAV AEG ALPL H AW+TALVFT  NA L+ VR+R E+  L  +
Sbjct  124  VAVAAEGLALPLAHGAWVTALVFTALNAALMVVRIRCEDGALARL  168


>gi|84497357|ref|ZP_00996179.1| hypothetical protein JNB_14223 [Janibacter sp. HTCC2649]
 gi|84382245|gb|EAP98127.1| hypothetical protein JNB_14223 [Janibacter sp. HTCC2649]
Length=185

 Score =  191 bits (486),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 99/166 (60%), Positives = 122/166 (74%), Gaps = 2/166 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            + +++  V  ERLAELVV+QRNA WSFA+GG E GR HY  MV+LHT  L   +VE + +
Sbjct  12   FVIVVALVAVERLAELVVSQRNASWSFARGGIETGREHYPFMVVLHTGFLAAMLVEAF-V  70

Query  62   HRPFIPW-LGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
             RP +P  L W MLA+VVASQ LRWWC+  LG+RWNTRVIV+P    VR GPYR++ HPN
Sbjct  71   RRPEVPAALAWSMLALVVASQVLRWWCITVLGQRWNTRVIVVPGLAPVRSGPYRFLSHPN  130

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVV EG ALPLVH +W+TA+ FT+ NA LL  RLRVEN+ L  +
Sbjct  131  YVAVVVEGAALPLVHASWITAVTFTVLNAALLRERLRVENAALAAL  176


>gi|21225930|ref|NP_631709.1| hypothetical protein SCO7670 [Streptomyces coelicolor A3(2)]
 gi|11493161|emb|CAC17487.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
Length=171

 Score =  191 bits (484),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 103/165 (63%), Positives = 124/165 (76%), Gaps = 0/165 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+LAV  ER+AELVVA+RNA W+ A+ G E GR HY VMV LHT LL  C++EP   
Sbjct  4    YALLVLAVAVERVAELVVARRNAAWTLARAGVEHGRGHYPVMVALHTGLLACCLLEPLLA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
              PF+P LGWPMLA+ +++Q LRWWC+ +LG  WNTRVIV+P    V  GPYR++RHPNY
Sbjct  64   DCPFLPALGWPMLALALSAQALRWWCIATLGPYWNTRVIVVPGTRPVGAGPYRFLRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            +AVV E  ALPLVH+AWLTA VFT ANA LLTVRLR EN+ L  +
Sbjct  124  LAVVVEVAALPLVHSAWLTAAVFTAANAMLLTVRLRCENTALAQL  168


>gi|258655219|ref|YP_003204375.1| isoprenylcysteine carboxyl methyltransferase [Nakamurella multipartita 
DSM 44233]
 gi|258558444|gb|ACV81386.1| Isoprenylcysteine carboxyl methyltransferase [Nakamurella multipartita 
DSM 44233]
Length=185

 Score =  186 bits (472),  Expect = 9e-46, Method: Compositional matrix adjust.
 Identities = 100/166 (61%), Positives = 125/166 (76%), Gaps = 2/166 (1%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            + +L+  V  ERLAELVV+ RNA WSFA GG+E GR HY VMV+LHT  L+  +VE + +
Sbjct  7    FVVLVALVGLERLAELVVSTRNATWSFAHGGRETGRGHYPVMVVLHTGFLVAMLVEAF-V  65

Query  62   HRPFIP-WLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
             RP +P WL W MLA+V+A+Q LRWWC+ +LG+RWNTRVIV+P    VR GPYRW+ HPN
Sbjct  66   RRPVVPGWLAWSMLALVLAAQALRWWCIATLGRRWNTRVIVVPGLPPVRSGPYRWLAHPN  125

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVV EG ALP+VH AW+TA+ FT+AN  LL VR+RVEN  L  +
Sbjct  126  YVAVVVEGVALPMVHAAWITAVTFTVANTALLAVRIRVENEALSAL  171


>gi|328887289|emb|CCA60528.1| hypothetical protein SVEN_7242 [Streptomyces venezuelae ATCC 
10712]
Length=171

 Score =  180 bits (457),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 108/163 (67%), Positives = 125/163 (77%), Gaps = 0/163 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y LL+ AV  ERL EL VA+RNA W+ A+ G E+GR HY VMV LHT LL+ C++EPW L
Sbjct  4    YTLLLAAVAAERLVELAVARRNAAWTLARLGVEYGRGHYPVMVALHTGLLVSCLIEPWLL  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF+P LGW M+ VVV +Q LRWWCV +LG  WNTRVIV+P   LVR GPYR++RHPNY
Sbjct  64   DRPFLPLLGWTMVVVVVLAQALRWWCVTTLGPYWNTRVIVVPGTRLVRAGPYRFVRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLG  164
            VAVVAE  ALPLVH+AWLTA  FT ANA LL VRLR EN+ LG
Sbjct  124  VAVVAEIVALPLVHSAWLTAAAFTAANALLLAVRLRCENAALG  166


>gi|320012403|gb|ADW07253.1| Isoprenylcysteine carboxyl methyltransferase [Streptomyces flavogriseus 
ATCC 33331]
Length=172

 Score =  172 bits (435),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 99/162 (62%), Positives = 119/162 (74%), Gaps = 0/162 (0%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y  L+LAV  ER+AELVVA RNARWS A+ G E GR HY  MV LH ALL+ C+ E W  
Sbjct  4    YTALVLAVAAERIAELVVALRNARWSLARSGTEAGRGHYPAMVALHAALLVACLAETWLA  63

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNY  121
             RPF   LGW M+AVV A+Q LRWWCV++LG+RWNTRVIV+P    V  GPYR +RHPNY
Sbjct  64   GRPFHALLGWTMVAVVAAAQVLRWWCVRTLGRRWNTRVIVVPGLPPVTGGPYRRLRHPNY  123

Query  122  VAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
             AV AEG ALPLVH AW+TA++FT++NA L+ VR+  E+  L
Sbjct  124  AAVAAEGAALPLVHGAWVTAVLFTVSNAALMAVRIPCEDGAL  165


>gi|88854528|ref|ZP_01129195.1| hypothetical protein A20C1_09929 [marine actinobacterium PHSC20C1]
 gi|88816336|gb|EAR26191.1| hypothetical protein A20C1_09929 [marine actinobacterium PHSC20C1]
Length=176

 Score =  165 bits (417),  Expect = 2e-39, Method: Compositional matrix adjust.
 Identities = 89/166 (54%), Positives = 113/166 (69%), Gaps = 4/166 (2%)

Query  2    YYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWAL  61
            Y  LIL    ERL EL +++RNA  +F +GG+E+G+ H+  MV LHT LL+ CV E    
Sbjct  6    YIALILGTGMERLYELRISKRNAAAAFERGGREYGQKHFPWMVALHTGLLIACVGEVIVA  65

Query  62   HRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVR-RGPYR--WMRH  118
             RPF+ WLG PML + + SQ  R+W + SLG +WNTRVIV+P A  V+ RGPYR  W+ H
Sbjct  66   DRPFLVWLGIPMLVITLLSQAARYWIINSLGAQWNTRVIVVPGAGRVQNRGPYRLTWLPH  125

Query  119  PNYVAVVAEGFALPLVHTAWLTALVFTLANAT-LLTVRLRVENSVL  163
            PNY+ V  EG ALPLVHTAW+TA+VFT+ NA  LL  R+  EN  L
Sbjct  126  PNYLVVAIEGIALPLVHTAWVTAIVFTVLNAVLLLAFRIPTENRAL  171


>gi|310818529|ref|YP_003950887.1| hypothetical protein STAUR_1256 [Stigmatella aurantiaca DW4/3-1]
 gi|309391601|gb|ADO69060.1| conserved uncharacterized protein [Stigmatella aurantiaca DW4/3-1]
Length=191

 Score =  164 bits (414),  Expect = 5e-39, Method: Compositional matrix adjust.
 Identities = 87/159 (55%), Positives = 112/159 (71%), Gaps = 0/159 (0%)

Query  8    AVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRPFIP  67
            A+  ERL ELV+++RNA  +FAQGG E G+ HY VMV+ H+  L+ CV E + L RPF  
Sbjct  15   ALAAERLVELVLSRRNAARAFAQGGLERGQGHYRVMVVFHSLFLVACVAEVFVLRRPFPG  74

Query  68   WLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNYVAVVAE  127
             LGW  L   V +Q LR+W + +LG+RWN+R+IV+P    V  GPYR++RHPNYVAVV E
Sbjct  75   ALGWAALGAAVMAQALRYWAIATLGERWNSRIIVIPGLPPVTGGPYRFLRHPNYVAVVLE  134

Query  128  GFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
              A+PL+H AWLTALVFT+ NA LL VR+R E   LG +
Sbjct  135  LLAVPLIHGAWLTALVFTVGNAALLYVRIRAEEQALGEV  173


>gi|115372824|ref|ZP_01460129.1| isoprenylcysteine carboxyl methyltransferase (icmt) family [Stigmatella 
aurantiaca DW4/3-1]
 gi|115370091|gb|EAU69021.1| isoprenylcysteine carboxyl methyltransferase (icmt) family [Stigmatella 
aurantiaca DW4/3-1]
Length=564

 Score =  161 bits (407),  Expect = 3e-38, Method: Compositional matrix adjust.
 Identities = 88/166 (54%), Positives = 115/166 (70%), Gaps = 0/166 (0%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            V+   + A+  ERL ELV+++RNA  +FAQGG E G+ HY VMV+ H+  L+ CV E + 
Sbjct  381  VFLGYMGALAAERLVELVLSRRNAARAFAQGGLERGQGHYRVMVVFHSLFLVACVAEVFV  440

Query  61   LHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPN  120
            L RPF   LGW  L   V +Q LR+W + +LG+RWN+R+IV+P    V  GPYR++RHPN
Sbjct  441  LRRPFPGALGWAALGAAVMAQALRYWAIATLGERWNSRIIVIPGLPPVTGGPYRFLRHPN  500

Query  121  YVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            YVAVV E  A+PL+H AWLTALVFT+ NA LL VR+R E   LG +
Sbjct  501  YVAVVLELLAVPLIHGAWLTALVFTVGNAALLYVRIRAEEQALGEV  546


>gi|126650524|ref|ZP_01722747.1| hypothetical protein BB14905_08038 [Bacillus sp. B14905]
 gi|126592680|gb|EAZ86679.1| hypothetical protein BB14905_08038 [Bacillus sp. B14905]
Length=180

 Score =  155 bits (393),  Expect = 1e-36, Method: Compositional matrix adjust.
 Identities = 74/164 (46%), Positives = 105/164 (65%), Gaps = 3/164 (1%)

Query  1    VYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWA  60
            ++YL++  V+ +RL E+V+A+RN +W  AQG  E G  HY  MV +H +  L  +VE   
Sbjct  2    IFYLIVTLVILQRLTEVVIAKRNEKWMIAQGAYEVGNSHYPYMVTMHISFFLFLIVEVVT  61

Query  61   LHRPFIPWLGWPMLAVV-VASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHP  119
             H    P   +P+  ++ VA Q LR WC++SLG  WNT++++LPHA +VR+GPY  MRHP
Sbjct  62   NHNGISPL--FPLFFILFVAVQALRIWCIRSLGTFWNTKILILPHAQVVRKGPYEIMRHP  119

Query  120  NYVAVVAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVL  163
            NY  V  E F LPL+  A+ TA  FTL N T+L+VR+ +E   L
Sbjct  120  NYAVVCLEIFLLPLMFQAYFTAFCFTLLNITMLSVRIPIEEKAL  163


>gi|338532316|ref|YP_004665650.1| hypothetical protein LILAB_13325 [Myxococcus fulvus HW-1]
 gi|337258412|gb|AEI64572.1| hypothetical protein LILAB_13325 [Myxococcus fulvus HW-1]
Length=191

 Score =  155 bits (393),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 83/162 (52%), Positives = 111/162 (69%), Gaps = 0/162 (0%)

Query  5    LILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRP  64
             + A++ ERL ELV+++RNA  +FA+GG E G+ HY  MV+ HT  L+ CV E + L R 
Sbjct  12   FMAALIVERLVELVLSKRNAARAFARGGVETGQRHYRFMVVFHTLFLVACVAEVFGLRRG  71

Query  65   FIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNYVAV  124
            F    GW  LA  V +QGLR+W + +LG RWN+R+IV+P    V  GPYR++RHPNYVAV
Sbjct  72   FPGAWGWAALAGAVLAQGLRYWAIATLGDRWNSRIIVVPGLAPVTGGPYRFLRHPNYVAV  131

Query  125  VAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            V E   +PL+H AW TALVF++ NA LL VR+R E + LG +
Sbjct  132  VLELACVPLIHGAWWTALVFSVGNAALLYVRIRAEEAALGEV  173


>gi|108760951|ref|YP_634755.1| hypothetical protein MXAN_6638 [Myxococcus xanthus DK 1622]
 gi|108464831|gb|ABF90016.1| conserved hypothetical protein [Myxococcus xanthus DK 1622]
Length=210

 Score =  155 bits (392),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 84/162 (52%), Positives = 111/162 (69%), Gaps = 0/162 (0%)

Query  5    LILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILHTALLLGCVVEPWALHRP  64
             + A+V ERL ELV+++RNA  +FA+GG E G+ HY  MV+ HT  L+ CV E + L R 
Sbjct  31   FMAALVVERLVELVLSKRNAARAFARGGVETGQRHYRFMVVFHTLFLVACVAEVFLLRRG  90

Query  65   FIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNTRVIVLPHATLVRRGPYRWMRHPNYVAV  124
            F    GW  LA  V +QGLR+W + +LG RWN+R+IV+P    V  GPYR++RHPNYVAV
Sbjct  91   FPGAWGWAALAGAVLAQGLRYWAIATLGDRWNSRIIVVPGLAPVTGGPYRFLRHPNYVAV  150

Query  125  VAEGFALPLVHTAWLTALVFTLANATLLTVRLRVENSVLGYI  166
            V E   +PL+H AW TALVF++ NA LL VR+R E + LG +
Sbjct  151  VLELACVPLIHGAWWTALVFSVGNAALLYVRIRAEEAALGEV  192



Lambda     K      H
   0.330    0.141    0.483 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 128142534078


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40