BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1146 Length=470 Score E Sequences producing significant alignments: (Bits) Value gi|148660933|ref|YP_001282456.1| putative transmembrane transpor... 925 0.0 gi|148822361|ref|YP_001287115.1| transmembrane transport protein... 925 0.0 gi|289555066|ref|ZP_06444276.1| LOW QUALITY PROTEIN: transmembra... 924 0.0 gi|254364051|ref|ZP_04980097.1| transmembrane transport protein ... 924 0.0 gi|323720428|gb|EGB29522.1| transmembrane transport protein mmpL... 923 0.0 gi|306781782|ref|ZP_07420119.1| transmembrane transporter mmpL13... 922 0.0 gi|15608286|ref|NP_215662.1| transmembrane transport protein Mmp... 920 0.0 gi|167969289|ref|ZP_02551566.1| putative transmembrane transport... 916 0.0 gi|31792340|ref|NP_854833.1| transmembrane transport protein Mmp... 877 0.0 gi|289749683|ref|ZP_06509061.1| transmembrane transporter mmpL13... 877 0.0 gi|340626160|ref|YP_004744612.1| putative transmembrane transpor... 876 0.0 gi|289446735|ref|ZP_06436479.1| transmembrane transporter mmpL13... 875 0.0 gi|289442577|ref|ZP_06432321.1| transmembrane transporter mmpL13... 875 0.0 gi|183984275|ref|YP_001852566.1| transmembrane transport protein... 724 0.0 gi|118616741|ref|YP_905073.1| transmembrane transport protein Mm... 715 0.0 gi|289569146|ref|ZP_06449373.1| transmembrane transporter mmpL13... 705 0.0 gi|240172478|ref|ZP_04751137.1| transmembrane transport protein ... 700 0.0 gi|118466696|ref|YP_880532.1| mmpL protein [Mycobacterium avium ... 694 0.0 gi|254774163|ref|ZP_05215679.1| mmpL protein [Mycobacterium aviu... 692 0.0 gi|336458778|gb|EGO37738.1| putative RND superfamily drug export... 691 0.0 gi|296170035|ref|ZP_06851639.1| integral membrane protein [Mycob... 690 0.0 gi|342861760|ref|ZP_08718406.1| mmpL protein [Mycobacterium colo... 689 0.0 gi|41408733|ref|NP_961569.1| hypothetical protein MAP2635c [Myco... 686 0.0 gi|254820695|ref|ZP_05225696.1| mmpL protein [Mycobacterium intr... 680 0.0 gi|145222719|ref|YP_001133397.1| MMPL domain-containing protein ... 583 2e-164 gi|120405525|ref|YP_955354.1| MMPL domain-containing protein [My... 582 3e-164 gi|333990399|ref|YP_004523013.1| transporter [Mycobacterium sp. ... 582 5e-164 gi|108801028|ref|YP_641225.1| MMPL [Mycobacterium sp. MCS] >gi|1... 572 7e-161 gi|126436864|ref|YP_001072555.1| MMPL domain-containing protein ... 569 4e-160 gi|119868413|ref|YP_938365.1| MMPL domain-containing protein [My... 566 2e-159 gi|108799297|ref|YP_639494.1| MMPL [Mycobacterium sp. MCS] >gi|1... 566 3e-159 gi|240171559|ref|ZP_04750218.1| transmembrane transport protein ... 565 6e-159 gi|41408422|ref|NP_961258.1| hypothetical protein MAP2324c [Myco... 560 2e-157 gi|336460998|gb|EGO39878.1| putative RND superfamily drug export... 560 2e-157 gi|118472917|ref|YP_889424.1| integral membrane protein [Mycobac... 559 3e-157 gi|254774486|ref|ZP_05216002.1| hypothetical protein MaviaA2_074... 556 4e-156 gi|118463097|ref|YP_880892.1| mmpl family protein [Mycobacterium... 556 4e-156 gi|145225715|ref|YP_001136393.1| MMPL domain-containing protein ... 554 2e-155 gi|315446066|ref|YP_004078945.1| RND superfamily drug exporter [... 552 5e-155 gi|296170417|ref|ZP_06852005.1| integral membrane protein [Mycob... 549 5e-154 gi|342857903|ref|ZP_08714559.1| mmpl family protein [Mycobacteri... 543 3e-152 gi|120402584|ref|YP_952413.1| polyprenyl synthetase [Mycobacteri... 536 2e-150 gi|120402209|ref|YP_952038.1| hypothetical protein Mvan_1197 [My... 535 1e-149 gi|254823131|ref|ZP_05228132.1| mmpl family protein [Mycobacteri... 531 8e-149 gi|183984778|ref|YP_001853069.1| transmembrane transport protein... 527 2e-147 gi|296165870|ref|ZP_06848353.1| mmpl family protein [Mycobacteri... 514 2e-143 gi|296167861|ref|ZP_06850044.1| integral membrane protein [Mycob... 507 2e-141 gi|169628380|ref|YP_001702029.1| MmpL family membrane protein [M... 496 3e-138 gi|240168626|ref|ZP_04747285.1| integral membrane protein [Mycob... 495 7e-138 gi|315441958|ref|YP_004074837.1| RND superfamily drug exporter [... 473 3e-131 >gi|148660933|ref|YP_001282456.1| putative transmembrane transport protein MmpL13b [Mycobacterium tuberculosis H37Ra] gi|148505085|gb|ABQ72894.1| putative conserved transmembrane transport protein MmpL13b [Mycobacterium tuberculosis H37Ra] Length=499 Score = 925 bits (2390), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 30 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 89 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 90 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 149 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 150 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 209 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 210 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 269 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 270 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 329 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 330 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 389 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 390 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 449 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 450 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 499 >gi|148822361|ref|YP_001287115.1| transmembrane transport protein mmpL13b [Mycobacterium tuberculosis F11] gi|297633688|ref|ZP_06951468.1| putative transmembrane transport protein [Mycobacterium tuberculosis KZN 4207] gi|297730675|ref|ZP_06959793.1| putative transmembrane transport protein [Mycobacterium tuberculosis KZN R506] 9 more sequence titles Length=500 Score = 925 bits (2390), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 31 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 90 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 91 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 150 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 151 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 210 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 211 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 270 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 271 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 330 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 331 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 390 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 391 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 450 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 451 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 500 >gi|289555066|ref|ZP_06444276.1| LOW QUALITY PROTEIN: transmembrane transporter mmpL13b [Mycobacterium tuberculosis KZN 605] gi|289439698|gb|EFD22191.1| LOW QUALITY PROTEIN: transmembrane transporter mmpL13b [Mycobacterium tuberculosis KZN 605] Length=515 Score = 924 bits (2389), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 46 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 105 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 106 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 165 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 166 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 225 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 226 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 285 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 286 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 345 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 346 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 405 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 406 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 465 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 466 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 515 >gi|254364051|ref|ZP_04980097.1| transmembrane transport protein mmpL13b [Mycobacterium tuberculosis str. Haarlem] gi|254550146|ref|ZP_05140593.1| putative transmembrane transport protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|134149565|gb|EBA41610.1| transmembrane transport protein mmpL13b [Mycobacterium tuberculosis str. Haarlem] Length=493 Score = 924 bits (2389), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 24 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 83 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 84 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 143 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 144 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 203 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 204 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 263 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 264 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 323 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 324 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 383 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 384 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 443 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 444 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 493 >gi|323720428|gb|EGB29522.1| transmembrane transport protein mmpL13b [Mycobacterium tuberculosis CDC1551A] Length=489 Score = 923 bits (2385), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 20 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 79 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 80 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 139 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 140 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 199 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 200 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 259 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 260 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 319 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 320 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 379 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 380 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 439 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 440 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 489 >gi|306781782|ref|ZP_07420119.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis SUMu002] gi|306783860|ref|ZP_07422182.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis SUMu003] gi|306788222|ref|ZP_07426544.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=500 Score = 922 bits (2382), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/470 (99%), Positives = 469/470 (99%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 31 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 90 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 91 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 150 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 151 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 210 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 211 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 270 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 271 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 330 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 331 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 390 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 391 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 450 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGG GKIAGRSDGQTIPASLTRNG Sbjct 451 PRPLAWLHERFGVSEAAEPVSRRRSHAGGSGKIAGRSDGQTIPASLTRNG 500 >gi|15608286|ref|NP_215662.1| transmembrane transport protein MmpL13B [Mycobacterium tuberculosis H37Rv] gi|253799811|ref|YP_003032812.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis KZN 1435] gi|289753213|ref|ZP_06512591.1| transmembrane transporter MmpL13 [Mycobacterium tuberculosis EAS054] 10 more sequence titles Length=470 Score = 920 bits (2379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/470 (99%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +ATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 1 MATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 >gi|167969289|ref|ZP_02551566.1| putative transmembrane transport protein mmpL13 [Mycobacterium tuberculosis H37Ra] Length=504 Score = 916 bits (2367), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/466 (100%), Positives = 466/466 (100%), Gaps = 0/466 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 31 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 90 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 91 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 150 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 151 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 210 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 211 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 270 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 271 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 330 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 331 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 390 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 391 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 450 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASL 466 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASL Sbjct 451 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASL 496 >gi|31792340|ref|NP_854833.1| transmembrane transport protein MmpL13 [Mycobacterium bovis AF2122/97] gi|121637078|ref|YP_977301.1| putative transmembrane transport protein mmpL13 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989551|ref|YP_002644238.1| putative transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] 12 more sequence titles Length=781 Score = 877 bits (2267), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 312 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 372 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 432 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 492 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 552 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 731 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 732 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 781 Score = 42.4 bits (98), Expect = 0.20, Method: Compositional matrix adjust. Identities = 82/337 (25%), Positives = 140/337 (42%), Gaps = 55/337 (16%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP--VELDSYAAE-LSR 145 GF D PRS SAR + ++L D FG + +V A P E+ + E L R Sbjct 42 GFQD----PRSESARAI-EVLTDKFGQSGQKMLIVVTAAAGADSPPAREVGTDIVEVLRR 96 Query 146 VPDVSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQ 203 P V V +P W P A L +G + L V + + A + + Sbjct 97 SPLVYNVTSP--------WTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQNHAQTLSDE 148 Query 204 VAGPAGRSVVMAG-----VAQVNRDSVDAVTDRLPMVLGLIAA-ITYVLLFLLTGSVVLP 257 VA V AG AQ+NR + D + +V+ LIA +++++L + G ++ Sbjct 149 VAHDRDGVTVRAGGSAMEYAQINRQNKDDL-----LVMELIAIPLSFLVLIWVFGGLLAA 203 Query 258 AKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF 317 + VL++ + L + T T N+ + L++DY + Sbjct 204 GLPMAQAVLAVVGSMAVLRLV--------TFATEVSTFALNLST---ALGLALAIDYTLL 252 Query 318 LVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIA 377 +VSR R+ L G+ R DE++ +A +GR + +A+ +++S +A Sbjct 253 IVSRYRDE-LAEGSDR-------------DEALIRTMATSGRTVLFSAVTVALSMSATAL 298 Query 378 AHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F VA AT +V+ PA + + G Sbjct 299 FPMYFLKSFAYAGVATVAFVAT-ASIVITPAAIVLLG 334 >gi|289749683|ref|ZP_06509061.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis T92] gi|289690270|gb|EFD57699.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis T92] Length=751 Score = 877 bits (2265), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 282 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 341 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 342 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 401 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 402 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 461 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 462 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 521 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 522 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 581 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 582 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 641 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 642 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 701 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 702 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 751 Score = 42.7 bits (99), Expect = 0.12, Method: Compositional matrix adjust. Identities = 83/337 (25%), Positives = 140/337 (42%), Gaps = 55/337 (16%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP--VELDSYAAE-LSR 145 GF D PRS SAR + ++L D FG + +V A P E+ + E L R Sbjct 12 GFQD----PRSESARAI-EVLTDKFGQSGQKMLIVVTAAAGADSPPAREVGTDIVEVLRR 66 Query 146 VPDVSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQ 203 P V V +P W P A L +G + L V + + A + + Sbjct 67 SPLVYNVTSP--------WTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQNHAQTLSDE 118 Query 204 VAGPAGRSVVMAG-----VAQVNRDSVDAVTDRLPMVLGLIAA-ITYVLLFLLTGSVVLP 257 VA V AG AQ+NR + D + +V+ LIA +++++L + G ++ Sbjct 119 VAHDRDGVTVRAGGSAMEYAQINRQNKDDL-----LVMELIAIPLSFLVLIWVFGGLLAA 173 Query 258 AKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF 317 + VL++ + L + T T N+ L L++DY + Sbjct 174 GLPMAQAVLAVVGSMAVLRLV--------TFATEVSTFALNLSTAL---GLALAIDYTLL 222 Query 318 LVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIA 377 +VSR R+ L G+ R DE++ +A +GR + +A+ +++S +A Sbjct 223 IVSRYRDE-LAEGSDR-------------DEALIRTMATSGRTVLFSAVTVALSMSATAL 268 Query 378 AHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F VA AT +V+ PA + + G Sbjct 269 FPMYFLKSFAYAGVATVAFVAT-ASIVITPAAIVLLG 304 >gi|340626160|ref|YP_004744612.1| putative transmembrane transport protein mmpl13 [Mycobacterium canettii CIPT 140010059] gi|340004350|emb|CCC43493.1| putative conserved transmembrane transport protein mmpl13 [Mycobacterium canettii CIPT 140010059] Length=781 Score = 876 bits (2263), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/470 (99%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 312 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 V+RRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 372 VIRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 432 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 492 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 552 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 731 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 732 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 781 Score = 42.0 bits (97), Expect = 0.20, Method: Compositional matrix adjust. Identities = 82/337 (25%), Positives = 140/337 (42%), Gaps = 55/337 (16%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP--VELDSYAAE-LSR 145 GF D PRS SAR + ++L D FG + +V A P E+ + E L R Sbjct 42 GFQD----PRSESARAI-EVLTDKFGQSGQKMLIVVTAAAGADSPPAREVGTDIVEVLRR 96 Query 146 VPDVSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQ 203 P V V +P W P A L +G + L V + + A + + Sbjct 97 SPLVYNVTSP--------WTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQNHAQTLSDE 148 Query 204 VAGPAGRSVVMAG-----VAQVNRDSVDAVTDRLPMVLGLIAA-ITYVLLFLLTGSVVLP 257 VA V AG AQ+NR + D + +V+ LIA +++++L + G ++ Sbjct 149 VAHDRDGVTVRAGGSAMEYAQINRQNKDDL-----LVMELIAIPLSFLVLIWVFGGLLAA 203 Query 258 AKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF 317 + VL++ + L + T T N+ + L++DY + Sbjct 204 GLPMAQAVLAVVGSMAVLRLV--------TFATEVSTFALNLST---ALGLALAIDYTLL 252 Query 318 LVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIA 377 +VSR R+ L G+ R DE++ +A +GR + +A+ +++S +A Sbjct 253 IVSRYRDE-LAEGSDR-------------DEALIRTMATSGRTVLFSAVTVALSMSATAL 298 Query 378 AHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F VA AT +V+ PA + + G Sbjct 299 FPMYFLKSFAYAGVATVAFVAT-ASIVITPAAIVLLG 334 >gi|289446735|ref|ZP_06436479.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis CPHL_A] gi|289419693|gb|EFD16894.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis CPHL_A] Length=838 Score = 875 bits (2262), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 369 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 428 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 429 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 488 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 489 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 548 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 549 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 608 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 609 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 668 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 669 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 728 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 729 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 788 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 789 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 838 Score = 42.7 bits (99), Expect = 0.13, Method: Compositional matrix adjust. Identities = 83/337 (25%), Positives = 140/337 (42%), Gaps = 55/337 (16%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP--VELDSYAAE-LSR 145 GF D PRS SAR + ++L D FG + +V A P E+ + E L R Sbjct 99 GFQD----PRSESARAI-EVLTDKFGQSGQKMLIVVTAAAGADSPPAREVGTDIVEVLRR 153 Query 146 VPDVSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQ 203 P V V +P W P A L +G + L V + + A + + Sbjct 154 SPLVYNVTSP--------WTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQNHAQTLSDE 205 Query 204 VAGPAGRSVVMAG-----VAQVNRDSVDAVTDRLPMVLGLIA-AITYVLLFLLTGSVVLP 257 VA V AG AQ+NR + D + +V+ LIA +++++L + G ++ Sbjct 206 VAHDRDGVTVRAGGSAMEYAQINRQNKDDL-----LVMELIAIPLSFLVLIWVFGGLLAA 260 Query 258 AKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF 317 + VL++ + L + T T N+ L L++DY + Sbjct 261 GLPMAQAVLAVVGSMAVLRLV--------TFATEVSTFALNLSTAL---GLALAIDYTLL 309 Query 318 LVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIA 377 +VSR R+ L G+ R DE++ +A +GR + +A+ +++S +A Sbjct 310 IVSRYRDE-LAEGSDR-------------DEALIRTMATSGRTVLFSAVTVALSMSATAL 355 Query 378 AHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F VA AT +V+ PA + + G Sbjct 356 FPMYFLKSFAYAGVATVAFVAT-ASIVITPAAIVLLG 391 >gi|289442577|ref|ZP_06432321.1| transmembrane transporter mmpL13 [Mycobacterium tuberculosis T46] gi|289415496|gb|EFD12736.1| transmembrane transporter mmpL13 [Mycobacterium tuberculosis T46] gi|339294137|gb|AEJ46248.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis CCDC5079] gi|339297778|gb|AEJ49888.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis CCDC5180] Length=839 Score = 875 bits (2261), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 370 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 429 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 430 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 489 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 490 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 549 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 550 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 609 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 610 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 669 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 670 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 729 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA Sbjct 730 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 789 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG Sbjct 790 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 839 Score = 42.7 bits (99), Expect = 0.14, Method: Compositional matrix adjust. Identities = 82/337 (25%), Positives = 140/337 (42%), Gaps = 55/337 (16%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP--VELDSYAAE-LSR 145 GF D PRS SAR + ++L D FG + +V A P E+ + E L R Sbjct 100 GFQD----PRSESARAI-EVLTDKFGQSGQKMLIVVTAAAGADSPPAREVGTDIVEVLRR 154 Query 146 VPDVSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQ 203 P V V +P W P A L +G + L V + + A + + Sbjct 155 SPLVYNVTSP--------WTVPPTAAADLLSTDGKSGLIVVNVKGGENDAQNHAQTLSDE 206 Query 204 VAGPAGRSVVMAG-----VAQVNRDSVDAVTDRLPMVLGLIA-AITYVLLFLLTGSVVLP 257 VA V AG AQ+NR + D + +V+ LIA +++++L + G ++ Sbjct 207 VAHDRDGVTVRAGGSAMEYAQINRQNKDDL-----LVMELIAIPLSFLVLIWVFGGLLAA 261 Query 258 AKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF 317 + VL++ + L + T T N+ + L++DY + Sbjct 262 GLPMAQAVLAVVGSMAVLRLV--------TFATEVSTFALNLST---ALGLALAIDYTLL 310 Query 318 LVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIA 377 +VSR R+ L G+ R DE++ +A +GR + +A+ +++S +A Sbjct 311 IVSRYRDE-LAEGSDR-------------DEALIRTMATSGRTVLFSAVTVALSMSATAL 356 Query 378 AHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F VA AT +V+ PA + + G Sbjct 357 FPMYFLKSFAYAGVATVAFVAT-ASIVITPAAIVLLG 392 >gi|183984275|ref|YP_001852566.1| transmembrane transport protein MmpL13 [Mycobacterium marinum M] gi|183177601|gb|ACC42711.1| conserved transmembrane transport protein MmpL13 [Mycobacterium marinum M] Length=780 Score = 724 bits (1870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/470 (80%), Positives = 413/470 (88%), Gaps = 4/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIV+TPAAIVLLGPRLDAL+VRRL RR+LGRP+P HKPV QLFWYRS+KF Sbjct 315 VATVAFVATASIVVTPAAIVLLGPRLDALNVRRLARRMLGRPEPQHKPVDQLFWYRSTKF 374 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRR LPVG AVVA+LV+LGLPF SVKWGFPDDRVLP +AS+ QVGD LR +F HD A Sbjct 375 VMRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNFAHDLAMA 434 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+VVPD RGL P +LD YAA+LSRVPDV++V AP+GTFV+GS VG P GATG ++GSAF Sbjct 435 VPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAF 494 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV STAPLFS ASDIQLKRLHQV GPAGR+V MAGVAQVNRDSVDAVT+RLP+VLGL+A Sbjct 495 LTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLGLMA 554 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSVVLPAKAL+CNVLSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 555 AITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 614 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLV+RIREYWL SGAARPA S A+ HAANDESVALG+ARTGRV Sbjct 615 VLLFCIAFGLSMDYEVFLVARIREYWLASGAARPATPSPAQAHAANDESVALGLARTGRV 674 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMV+VPAFMHV GRWNWWA Sbjct 675 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVPAFMHVMGRWNWWA 734 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 P+PL WLH+RFG+SE + + A R D TIPA+L+ G Sbjct 735 PKPLVWLHQRFGISETGAVGDADAAAT----EAADRRDRPTIPAALSGRG 780 >gi|118616741|ref|YP_905073.1| transmembrane transport protein MmpL13 [Mycobacterium ulcerans Agy99] gi|118568851|gb|ABL03602.1| conserved transmembrane transport protein MmpL13 [Mycobacterium ulcerans Agy99] Length=780 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/470 (79%), Positives = 409/470 (88%), Gaps = 4/470 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIV+TPAAIVLLGPRLDAL+VRRL RR+LGRP P HKPV QLFWYRS+KF Sbjct 315 VATVAFVATASIVVTPAAIVLLGPRLDALNVRRLARRMLGRPKPQHKPVDQLFWYRSTKF 374 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRR LPVG AVVA+LV+LGLPF SVKWGFPDDRVLP +AS+ QVGD LR +F HD A Sbjct 375 VMRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNFAHDLAMA 434 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+VVPD GL P +LD YAA+LSRVPDV++V AP+GTFV+GS VG P GATG ++GSAF Sbjct 435 VPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAF 494 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV STAPLFS ASDIQLKRLHQV GPAGR+V MAGVAQVNRDSVDAVT+RLP+VLGL+A Sbjct 495 LTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLGLMA 554 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSVVLPAKAL+CNVLSLTAAFGALVWIFQ+GH GALGT PSGTLVANMP Sbjct 555 AITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMP 614 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLV+RIREYWL SGAA PA S A+ HAANDESVALG+ARTGRV Sbjct 615 VLLFCIAFGLSMDYEVFLVARIREYWLASGAAGPATPSPAQAHAANDESVALGLARTGRV 674 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLA+AADATLVRMV+VPAFMHV GRWNWWA Sbjct 675 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVPAFMHVMGRWNWWA 734 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 P+PL WLH+RFG+SE + + A R D TIPA+L+ G Sbjct 735 PKPLVWLHQRFGISETGAVGGADAAAT----EAADRRDRPTIPAALSGRG 780 Score = 37.0 bits (84), Expect = 7.7, Method: Compositional matrix adjust. Identities = 87/367 (24%), Positives = 156/367 (43%), Gaps = 58/367 (15%) Query 63 RRWLPVGTAVVALLVLLGLPFLSV--KWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 RR + V V + G+P + + GF D P + SAR + +L D FG Q Sbjct 14 RRIIGVALLVFIAAAVFGIPVANSLSRGGFQD----PNAESARAI-KVLADKFGQS-GQQ 67 Query 121 IPIVVPDARGLGPVELDSYA----AELSRVPDVSAVAAP-TGTFVDGSWVGTPRGATGL- 174 + I+V G+G + AEL+ P V V++P TG D P+ A L Sbjct 68 MLILVTAPGGVGTERARAVGTDIVAELNHSPLVFNVSSPWTGPSAD------PKSAPDLV 121 Query 175 -AEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAG-----VAQVNRDSVDAV 228 +G + L V + S A ++ V AG AQ+N+ + D + Sbjct 122 SKDGKSGLIVVNIKGGESNAQKNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDL 181 Query 229 TDRLPMVLGLIA-AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGAL 287 +V+ LIA +++++L + G ++ A + L++ + L + Sbjct 182 -----LVMELIAIPLSFLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLV--------T 228 Query 288 GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAAND 347 TT N+ + L++DY + ++SR R+ L G++R + Sbjct 229 FTTDVSIFALNLST---ALGLALAIDYTLLIISRYRDE-LAEGSSR-------------E 271 Query 348 ESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP 407 E++ +A +GR + +A+ +++S +A +A + F++ F VA AT +VV P Sbjct 272 EALVRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVAT-ASIVVTP 330 Query 408 AFMHVTG 414 A + + G Sbjct 331 AAIVLLG 337 >gi|289569146|ref|ZP_06449373.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis T17] gi|289542900|gb|EFD46548.1| transmembrane transporter mmpL13b [Mycobacterium tuberculosis T17] Length=427 Score = 705 bits (1820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/362 (99%), Positives = 362/362 (100%), Gaps = 0/362 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +ATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF Sbjct 1 MATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ Sbjct 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF Sbjct 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA Sbjct 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP Sbjct 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV Sbjct 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 Query 361 IT 362 IT Sbjct 361 IT 362 >gi|240172478|ref|ZP_04751137.1| transmembrane transport protein MmpL13 [Mycobacterium kansasii ATCC 12478] Length=774 Score = 700 bits (1806), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/460 (81%), Positives = 401/460 (88%), Gaps = 8/460 (1%) Query 11 SIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGT 70 SI+ITPAAIVLLGPRLDA DVRRL+RR+LGRP+PVHKPV+QLFWYRS+KFVMRRWLP+G Sbjct 323 SIMITPAAIVLLGPRLDAWDVRRLIRRMLGRPEPVHKPVEQLFWYRSTKFVMRRWLPIGL 382 Query 71 AVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARG 130 AV+ALLVLLGLPFLSVKWGFPDDRVLPR+ASA QVGD LR DF HD A +P+VVPDARG Sbjct 383 AVLALLVLLGLPFLSVKWGFPDDRVLPRTASAHQVGDRLRKDFAHDLAMAVPVVVPDARG 442 Query 131 LGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLF 190 L P +LD YAA+LSRVPDVS+V+AP+GTFV G+ VG P GATG A+GSAFLTV S APLF Sbjct 443 LTPADLDGYAADLSRVPDVSSVSAPSGTFVGGNKVGPPAGATGFADGSAFLTVYSIAPLF 502 Query 191 SRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLL 250 S+ASD QL RLHQV GPAGRSV MAGV QVNRDSV AVTDRLP+VLGL+A IT VLLFLL Sbjct 503 SQASDTQLTRLHQVGGPAGRSVEMAGVVQVNRDSVAAVTDRLPLVLGLMAVITLVLLFLL 562 Query 251 TGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGL 310 TGSVVLP KALVCNVLSL+AAFGALVWIFQ+GH GALGTTPSGTLVANMPVLLFCIAFGL Sbjct 563 TGSVVLPVKALVCNVLSLSAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGL 622 Query 311 SMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSM 370 SMDYEVFLV+RIREYWL SGAARPA + AE HAANDESVALGVARTGRVITAAALVMSM Sbjct 623 SMDYEVFLVARIREYWLASGAARPATPNPAEAHAANDESVALGVARTGRVITAAALVMSM 682 Query 371 SFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHER 430 SFAALIAAHVSFMRMFGLGLTLAVAADATLVR+V+VPAFMHV G WNWWAP+PL WLHER Sbjct 683 SFAALIAAHVSFMRMFGLGLTLAVAADATLVRVVLVPAFMHVMGSWNWWAPKPLVWLHER 742 Query 431 FGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG 470 FG+SE A H K A R + IPA+LT G Sbjct 743 FGISEGAA-----VEHG---AKTASRCEEPAIPAALTGKG 774 >gi|118466696|ref|YP_880532.1| mmpL protein [Mycobacterium avium 104] gi|118167983|gb|ABK68880.1| mmpL protein [Mycobacterium avium 104] Length=808 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/445 (84%), Positives = 396/445 (89%), Gaps = 0/445 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLG RLDALDVRRL+RR L R PV KPV+QLFWYRSSKF Sbjct 312 VATVAFVATASIVITPAAIVLLGDRLDALDVRRLLRRALRRAQPVRKPVEQLFWYRSSKF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW PVG VV LL+LLGLPF SVKWGFPDDRVLPRSASA QVGD LR F HD AT Sbjct 372 VMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGFAHDSATS 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+V+PDA GL P +LD YAA LSRVPDVSAV+AP GTF G+ VG P GATGL +GSAF Sbjct 432 VPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFS A+D+QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+A Sbjct 492 LTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSV+LPAKAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 552 AITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPAR + HAANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPAFMHV GRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWA 731 Query 421 PRPLAWLHERFGVSEAAEPVSRRRS 445 P+PLAWLH+RFG+SEAA+ R R+ Sbjct 732 PKPLAWLHDRFGISEAADEEPRLRA 756 >gi|254774163|ref|ZP_05215679.1| mmpL protein [Mycobacterium avium subsp. avium ATCC 25291] Length=808 Score = 692 bits (1785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/445 (84%), Positives = 395/445 (89%), Gaps = 0/445 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLG RLDALDVRRL+RR L R PV KPV+QLFWYRSSKF Sbjct 312 VATVAFVATASIVITPAAIVLLGDRLDALDVRRLLRRALRRAQPVRKPVEQLFWYRSSKF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW PVG VV LL+LLGLPF SVKWGFPDDRVLPRSASA QVGD LR F HD AT Sbjct 372 VMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGFAHDSATS 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+V+PDA GL P +LD YAA LSRVPDVSAV+AP GTF G+ VG P GATGL + SAF Sbjct 432 VPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDSSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFS A+D+QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+A Sbjct 492 LTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSV+LPAKAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 552 AITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPAR + HAANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPAFMHV GRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWA 731 Query 421 PRPLAWLHERFGVSEAAEPVSRRRS 445 P+PLAWLH+RFG+SEAA+ R R+ Sbjct 732 PKPLAWLHDRFGISEAADEEPRLRA 756 >gi|336458778|gb|EGO37738.1| putative RND superfamily drug exporter [Mycobacterium avium subsp. paratuberculosis S397] Length=780 Score = 691 bits (1783), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/449 (83%), Positives = 395/449 (88%), Gaps = 0/449 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLG RLDALDVRRL+RR L R PV KPV+QLFWYRSSKF Sbjct 312 VATVAFVATASIVITPAAIVLLGDRLDALDVRRLLRRALRRAQPVRKPVEQLFWYRSSKF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW PVG VV LL+LLGLPF SVKWGFPDDRVLPRSASA QVGD LR F HD AT Sbjct 372 VMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGFAHDSATS 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 P+V+PDA GL P +LD YAA LSRVPDVSAV+AP GTF G+ VG P GATGL +GSAF Sbjct 432 APVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFS A+D+QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+A Sbjct 492 LTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSV+LPAKAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 552 AITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPAR + HAANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPAFMHV GRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWA 731 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGG 449 P+PLAWLH+RFG+SEAA+ R A G Sbjct 732 PKPLAWLHDRFGISEAADEEPRLAEPARG 760 >gi|296170035|ref|ZP_06851639.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895303|gb|EFG75012.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=773 Score = 690 bits (1780), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/436 (84%), Positives = 396/436 (91%), Gaps = 0/436 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLGPRLDALDVRRL+RR+ RP+P HKPV+QLFWYRS+K Sbjct 312 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLLRRVFRRPEPAHKPVEQLFWYRSTKL 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW P+G VVALL+LLGLPFLSVKWGFPDDRVLP SAS+ +VGD LR+DF D AT Sbjct 372 VMRRWAPIGLTVVALLLLLGLPFLSVKWGFPDDRVLPPSASSHRVGDRLRNDFADDSATS 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+VVPDARGL P +LDSYAA LSRVPDVS V++P GTFV G+ G P GATG+A+GSAF Sbjct 432 VPVVVPDARGLKPADLDSYAAALSRVPDVSEVSSPGGTFVGGNRTGPPAGATGIADGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LT+SSTAPLFS A+D QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+A Sbjct 492 LTISSTAPLFSAANDAQLKRLHEVPGPAGRSVAMGGVAQVNRDSVDAVTDRLPLVLGLMA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+ LLFLLTGSV+LPAKAL CNVLSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 552 AITFALLFLLTGSVLLPAKALACNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPA+ S + AANDESVALGVARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPAKPSPKQADAANDESVALGVARTGRV 671 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPAFMHV GRWNWWA Sbjct 672 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWA 731 Query 421 PRPLAWLHERFGVSEA 436 PRPLAWLH+RFG+SEA Sbjct 732 PRPLAWLHDRFGISEA 747 >gi|342861760|ref|ZP_08718406.1| mmpL protein [Mycobacterium colombiense CECT 3035] gi|342130894|gb|EGT84190.1| mmpL protein [Mycobacterium colombiense CECT 3035] Length=777 Score = 689 bits (1777), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/431 (84%), Positives = 386/431 (90%), Gaps = 2/431 (0%) Query 11 SIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGT 70 SIVITPAAIVLLGPRLDAL+VRRL RR+LGRP+P HKPV+QLFWYRS+KFVMRRW P+G Sbjct 322 SIVITPAAIVLLGPRLDALNVRRLGRRMLGRPEPAHKPVEQLFWYRSTKFVMRRWAPIGL 381 Query 71 AVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARG 130 VVALL+LLG PFL V WGFPDDRVLPRSASA QVGD LR+ F D AT +P+VVPDA G Sbjct 382 TVVALLLLLGYPFLRVTWGFPDDRVLPRSASAHQVGDRLRNGFERDSATSVPVVVPDATG 441 Query 131 LGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLF 190 LGP + D+YAA LSRV DVSAVAAP GTF G+ VG P GATGL +GSAFLTVSSTAPLF Sbjct 442 LGPADFDNYAAALSRVADVSAVAAPGGTFTAGNRVGPPAGATGLHDGSAFLTVSSTAPLF 501 Query 191 SRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLL 250 S A+D QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+AAIT+VLLFLL Sbjct 502 STANDTQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLL 561 Query 251 TGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGL 310 TGSV+LPAKAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMPVLLFCIAFGL Sbjct 562 TGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGL 621 Query 311 SMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSM 370 SMDYEVFL+SRIREYWL SGAARPAR + + HAANDESVALGVARTGRVITAAALVMSM Sbjct 622 SMDYEVFLLSRIREYWLSSGAARPARPTAKQAHAANDESVALGVARTGRVITAAALVMSM 681 Query 371 SFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHER 430 SFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPAFMHV GRWNWWAP+PLAWLH+R Sbjct 682 SFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWAPKPLAWLHDR 741 Query 431 FGVSE--AAEP 439 FG+SE A EP Sbjct 742 FGISEGGAEEP 752 >gi|41408733|ref|NP_961569.1| hypothetical protein MAP2635c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397091|gb|AAS04952.1| hypothetical protein MAP_2635c [Mycobacterium avium subsp. paratuberculosis K-10] Length=800 Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/442 (84%), Positives = 392/442 (89%), Gaps = 0/442 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLG RLDALDVRRL+RR L R PV KPV+QLFWYRSSKF Sbjct 332 VATVAFVATASIVITPAAIVLLGDRLDALDVRRLLRRALRRAQPVRKPVEQLFWYRSSKF 391 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW PVG VV LL+LLGLPF SVKWGFPDDRVLPRSASA QVGD LR F HD AT Sbjct 392 VMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGFAHDSATS 451 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+V+PDA GL P +LD YAA LSRVPDVSAV+A GTF G+ VG P GATGL +GSAF Sbjct 452 VPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSALGGTFTGGTRVGPPAGATGLGDGSAF 511 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFS A+D+QLKRLH+V GPAGRSV M GVAQVNRDSVDAVTDRLP+VLGL+A Sbjct 512 LTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMA 571 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSV+LPAKAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 572 AITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 631 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPAR + HAANDESVALGVARTGRV Sbjct 632 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRV 691 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAV ADATLVRMVVVPA MHV GRWNWWA Sbjct 692 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPASMHVMGRWNWWA 751 Query 421 PRPLAWLHERFGVSEAAEPVSR 442 P+PLAWLH+RFG+SEAA+ R Sbjct 752 PKPLAWLHDRFGISEAADEEPR 773 >gi|254820695|ref|ZP_05225696.1| mmpL protein [Mycobacterium intracellulare ATCC 13950] Length=771 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/438 (83%), Positives = 390/438 (90%), Gaps = 0/438 (0%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVATASIVITPAAIVLLG RLDA +VRR +RR+L RP+P KPV+QLFWYRSSKF Sbjct 310 VATVAFVATASIVITPAAIVLLGDRLDAFNVRRFLRRMLRRPEPAPKPVEQLFWYRSSKF 369 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRRW PVG AVV LL+LLGLPF SVKWGFPDDRVLPRSASA QVGD LR+DF D AT Sbjct 370 VMRRWAPVGLAVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRNDFADDSATS 429 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 +P+VVPDA GL P + DSYAA LSRVPDV+AV+AP GTF G+ VG P GATGLA+GSAF Sbjct 430 VPVVVPDASGLNPGDFDSYAAALSRVPDVAAVSAPGGTFTGGNRVGPPAGATGLAQGSAF 489 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTVSSTAPLFS A+D QL RLH V GPAGR+V M GVAQVNRDSVDAVT+RLP+VLGL+A Sbjct 490 LTVSSTAPLFSAANDAQLARLHDVPGPAGRAVEMGGVAQVNRDSVDAVTERLPLVLGLMA 549 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSV+LP KAL CN LSLTAAFGALVWIFQ+GH GALGTTPSGTLVANMP Sbjct 550 AITFVLLFLLTGSVLLPIKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMP 609 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIREYWL SGAARPAR + + HAANDESVALGVARTGRV Sbjct 610 VLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKQAHAANDESVALGVARTGRV 669 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMSMSFAALIAAHVSFMRMFGLGL LAV ADATLVRMVVVPAFMHV GRWNWWA Sbjct 670 ITAAALVMSMSFAALIAAHVSFMRMFGLGLVLAVFADATLVRMVVVPAFMHVMGRWNWWA 729 Query 421 PRPLAWLHERFGVSEAAE 438 PRPLAWLH+RFG+SE + Sbjct 730 PRPLAWLHDRFGISEGVD 747 >gi|145222719|ref|YP_001133397.1| MMPL domain-containing protein [Mycobacterium gilvum PYR-GCK] gi|315443184|ref|YP_004076063.1| RND superfamily drug exporter [Mycobacterium sp. Spyr1] gi|145215205|gb|ABP44609.1| MMPL domain protein [Mycobacterium gilvum PYR-GCK] gi|315261487|gb|ADT98228.1| predicted RND superfamily drug exporter [Mycobacterium sp. Spyr1] Length=738 Score = 583 bits (1503), Expect = 2e-164, Method: Compositional matrix adjust. Identities = 305/435 (71%), Positives = 351/435 (81%), Gaps = 14/435 (3%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +A V+F A A+IV+TPAAI L G RLDALDVRRLVRR+LGRPDPV KPV+Q FWYRS+ F Sbjct 312 IAVVSFAALAAIVVTPAAIALAGDRLDALDVRRLVRRILGRPDPVAKPVEQNFWYRSTTF 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMRR +P+G VV LLVLLG PFL WGFPDDRVLP +ASARQ+GD LR DF D +T Sbjct 372 VMRRSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQDFAVDSSTN 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + +V+PDA G+ + D+YA LS V DVS+V+AP+GTF+ G+ G P ATG A+GSAF Sbjct 432 VVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIGGARAGPPSAATGSADGSAF 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LT+ S APLF+ AS++QL RLH +A P R V++ G+AQ+NRDS DA+T RLP+VL +IA Sbjct 492 LTIGSRAPLFTDASEVQLDRLHAIAPPGDRQVLLTGLAQINRDSADAITSRLPLVLAVIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLF+LTGSVVLP KALV NVLSLTAAFGALVWIFQEGH GALGTTP+GTLVA MP Sbjct 552 AITFVLLFVLTGSVVLPLKALVLNVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFLVSRIREYWLE+G N SVALG+ARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLVSRIREYWLETG--------------ENGRSVALGLARTGRV 657 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 +TAAALVMS+SFAALIAA VSFMRMFG GLTLAV DATLVRM++VPAFMH+ GRWNWWA Sbjct 658 VTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLLVPAFMHLLGRWNWWA 717 Query 421 PRPLAWLHERFGVSE 435 P PLA LH R GVSE Sbjct 718 PPPLARLHARIGVSE 732 Score = 39.7 bits (91), Expect = 1.1, Method: Compositional matrix adjust. Identities = 79/335 (24%), Positives = 134/335 (40%), Gaps = 51/335 (15%) Query 89 GFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPD 148 GF D P S SAR +L D FG I V D P D + R+ D Sbjct 42 GFQD----PTSESARAT-QMLVDTFGQGDMELILAVTSDDGAQSPAARDVGVELVERLSD 96 Query 149 VSAVAAPTGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQVAG 206 VAA T +W P A L +G L V+ S A + ++ Sbjct 97 SPHVAAITS-----AWTSPPSAAPALISEDGRTGLIVAGITGGESGAQKLAKALTDELVY 151 Query 207 PAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAA-ITYVLLFLLTGSVVLPAKALVCNV 265 V AG A + ++ T++ +++ IA +++V+L + G ++ A L V Sbjct 152 DRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLSFVVLVWVFGGLLAAALPLAVGV 211 Query 266 LSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPV--LLFCIAFGLSM--DYEVFLVSR 321 ++ G++ TLV ++ + L IA GL++ DY + ++SR Sbjct 212 FAI---------------LGSMAVLRGFTLVTDVSIFALNLSIAMGLALAIDYTLLIISR 256 Query 322 IREYWLESGAARPARRSVAEVHAANDESVAL--GVARTGRVITAAALVMSMSFAALIAAH 379 R+ E+ +D AL + GR + +A +++S A++ Sbjct 257 YRD----------------ELADGHDRDTALLRTMTTAGRTVVFSATTVALSMVAMVLFP 300 Query 380 VSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 + F++ F +AV + A L +VV PA + + G Sbjct 301 MYFLKSFAYA-GIAVVSFAALAAIVVTPAAIALAG 334 >gi|120405525|ref|YP_955354.1| MMPL domain-containing protein [Mycobacterium vanbaalenii PYR-1] gi|119958343|gb|ABM15348.1| MMPL domain protein [Mycobacterium vanbaalenii PYR-1] Length=778 Score = 582 bits (1501), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 314/437 (72%), Positives = 357/437 (82%), Gaps = 12/437 (2%) Query 21 LLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLG 80 L G RLD++DVRRLVRR+LGRP+PV KPV+Q+FWYRS+KFVMRR +P+G VV LL+LLG Sbjct 335 LAGARLDSMDVRRLVRRVLGRPEPVAKPVEQMFWYRSTKFVMRRSIPIGVVVVTLLLLLG 394 Query 81 LPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYA 140 PFL WGFPDDRVLP+SASARQVGD LR DF D + + +V+PDA GLGP LD YA Sbjct 395 APFLGANWGFPDDRVLPQSASARQVGDELRTDFAVDSSANVVVVLPDAEGLGPDALDGYA 454 Query 141 AELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKR 200 AELSRV DVS+V+AP GTFVDG+ G P ATG+AEGSAFLT+ STAPLF+ AS+ QL R Sbjct 455 AELSRVQDVSSVSAPGGTFVDGAKAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDR 514 Query 201 LHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKA 260 LH VA P GR V++ G+AQ+NRDS DA+T RLP VL +IAAIT+VLLFLLTGSVVLP KA Sbjct 515 LHDVAPPEGRDVLLTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKA 574 Query 261 LVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVS 320 LV NVLSLTAAFGALVWIFQ+GH GALGTTP+GTLVANMPVLLFCIAFGLSMDYEVFLVS Sbjct 575 LVLNVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLSMDYEVFLVS 634 Query 321 RIREYWLESGAARPARRSVAEV-------HAANDESVALGVARTGRVITAAALVMSMSFA 373 RIREYWL SG A A S A H +DESVALG+ARTGRV+TAAAL+MS+SFA Sbjct 635 RIREYWLASGGAG-ADSSTAHQRSDDLAPHVRSDESVALGLARTGRVVTAAALLMSISFA 693 Query 374 ALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGV 433 ALIAA V+FMRMFG+GLTLA+ ADATLVRM++VPAFMHV GRWNWWAP+PLA LHER G Sbjct 694 ALIAAKVAFMRMFGVGLTLAILADATLVRMLLVPAFMHVLGRWNWWAPKPLARLHERIGF 753 Query 434 SEAAEPVS----RRRSH 446 SE + S R R H Sbjct 754 SETLDDSSDSPPRSRQH 770 >gi|333990399|ref|YP_004523013.1| transporter [Mycobacterium sp. JDM601] gi|333486367|gb|AEF35759.1| transmembrane transport protein MmpL13 [Mycobacterium sp. JDM601] Length=788 Score = 582 bits (1500), Expect = 5e-164, Method: Compositional matrix adjust. Identities = 311/452 (69%), Positives = 355/452 (79%), Gaps = 16/452 (3%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VATVAFVA A+IV+TPA IV+LG RLDALD+ RL RRLL R +P KPV+Q FW+RS+ Sbjct 312 VATVAFVACAAIVLTPALIVVLGARLDALDMHRLARRLLSRGEPEPKPVEQQFWHRSTTA 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 V+R +PV A V +LVLLG PFL VKWGFPDDR LPRSASA QVGD LR F D + Sbjct 372 VIRHAVPVAVAGVTVLVLLGTPFLGVKWGFPDDRALPRSASAHQVGDRLRTGFADDSSAT 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 I VVP+A GL P +L+ YAA LS V VSAV APT TFV+G G P TGL +G A Sbjct 432 ISAVVPEAAGLAPGDLERYAAALSAVTHVSAVTAPTATFVNGQPAGPPAAPTGLVDGFAL 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 +T++STAPLFS SD QL +LHQ+AGPAG++V+ AG+AQ NRDSV A+T RLP+VLGLIA Sbjct 492 VTIASTAPLFSADSDDQLDQLHQIAGPAGKTVLFAGLAQNNRDSVAAITSRLPLVLGLIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 AIT+VLLFLLTGSVVLP KALV NVLSLTAAFGALVWIFQ+GHFGA GTTP+GTLVANMP Sbjct 552 AITFVLLFLLTGSVVLPVKALVLNVLSLTAAFGALVWIFQDGHFGAFGTTPTGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFC+AFGLSMDYEVFL++RIREYWL SG R+ A+ ND SVALG+ARTGRV Sbjct 612 VLLFCVAFGLSMDYEVFLIARIREYWLASG------RTPAD----NDASVALGLARTGRV 661 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAALVMS+SFAALIAAHVSFMRMFG+GLTLAV DATLVR V+VPAFMH+ GR NWWA Sbjct 662 ITAAALVMSISFAALIAAHVSFMRMFGVGLTLAVLTDATLVRTVLVPAFMHLMGRANWWA 721 Query 421 PRPLAWLHERFGVSEAAEPVS------RRRSH 446 P LA LH+R G+SE P + RR H Sbjct 722 PGLLARLHDRVGLSEDHTPEASAAERHRRSGH 753 >gi|108801028|ref|YP_641225.1| MMPL [Mycobacterium sp. MCS] gi|119870169|ref|YP_940121.1| MMPL domain-containing protein [Mycobacterium sp. KMS] gi|108771447|gb|ABG10169.1| MMPL [Mycobacterium sp. MCS] gi|119696258|gb|ABL93331.1| MMPL domain protein [Mycobacterium sp. KMS] Length=769 Score = 572 bits (1473), Expect = 7e-161, Method: Compositional matrix adjust. Identities = 306/447 (69%), Positives = 366/447 (82%), Gaps = 8/447 (1%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +A V F ATA+IV+ PAAI LLG RLD DVRRL RRLLGRP+P K V++ FWYRS+K+ Sbjct 312 LAVVGFAATAAIVVAPAAIALLGNRLDDFDVRRLARRLLGRPEPTPKSVEETFWYRSTKY 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 V RR +P+G A+VALL++LG PFLS+KWGFPDDRVLP+S+SARQVGD LR +F D AT Sbjct 372 VQRRSIPIGVAIVALLLVLGAPFLSIKWGFPDDRVLPQSSSARQVGDELRTNFAVDTATD 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + +VVPD GL P ++D YAA+LSRVPDV +VAAP GT+V G+ VG P A+GL GSA+ Sbjct 432 VTVVVPDTGGLTPADIDRYAADLSRVPDVLSVAAPGGTYVTGARVGPPSAASGLGAGSAY 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV++ LFS S+ QL LH VA P G +V G AQ+NRDS +++T RLP+VLG+IA Sbjct 492 LTVATNTELFSDESERQLDALHAVAPPGGTAVQFTGTAQINRDSSESITSRLPLVLGIIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 I++VLLFLLTGSVVLP KAL+ NVLSL+AAFGALVWIFQEGH GALGTTP+GTLVANMP Sbjct 552 GISFVLLFLLTGSVVLPLKALLLNVLSLSAAFGALVWIFQEGHLGALGTTPTGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAAR-----PARRSVAEVHAA---NDESVAL 352 VLLFCIAFGLSMDYEVFL+SRIRE+WL+SG R PA R ++ A NDESVAL Sbjct 612 VLLFCIAFGLSMDYEVFLMSRIREFWLKSGRTRQDGTVPAPRVRNDLSAPRVRNDESVAL 671 Query 353 GVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHV 412 G+ARTGRV+TAAAL+M++SFAALIAA VSFMRMFG+G TLAV ADATL+RM++VPAFMH+ Sbjct 672 GLARTGRVVTAAALLMTISFAALIAAQVSFMRMFGVGFTLAVLADATLIRMLLVPAFMHL 731 Query 413 TGRWNWWAPRPLAWLHERFGVSEAAEP 439 GRWNWWAP+PLA LHERFG+SE+AEP Sbjct 732 MGRWNWWAPKPLARLHERFGISESAEP 758 >gi|126436864|ref|YP_001072555.1| MMPL domain-containing protein [Mycobacterium sp. JLS] gi|126236664|gb|ABO00065.1| MMPL domain protein [Mycobacterium sp. JLS] Length=751 Score = 569 bits (1466), Expect = 4e-160, Method: Compositional matrix adjust. Identities = 301/439 (69%), Positives = 360/439 (83%), Gaps = 10/439 (2%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +A V F ATA+IV+ PAAI LLG +LD DVRRL RRLLGRP+P K V++ FWYRS+K+ Sbjct 312 LAVVGFAATAAIVVAPAAIALLGNQLDDFDVRRLARRLLGRPEPTPKSVEETFWYRSTKY 371 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 V RR +P+G A+VALL++LG PFLS+KWGFPDDRVLP+S+SARQVGD LR +F D AT Sbjct 372 VQRRSIPIGVAIVALLLVLGAPFLSIKWGFPDDRVLPQSSSARQVGDELRTNFAVDTATD 431 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + +VVPD GL P ++D YAA+LSRVPDV +VAAP GT+V G+ VG P A+GL GSA+ Sbjct 432 VTVVVPDTGGLTPADIDRYAADLSRVPDVLSVAAPGGTYVTGARVGPPSAASGLGAGSAY 491 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV++ LFS S+ QL LH VA P G +V G AQ+NRDS +++T RLP+VLG+IA Sbjct 492 LTVATNTELFSDESERQLDALHAVAPPGGTAVQFTGTAQINRDSSESITSRLPLVLGIIA 551 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 I++VLLFLLTGSVVLP KAL+ NVLSL+AAFGALVWIFQEGH GALGTTP+GTLVANMP Sbjct 552 GISFVLLFLLTGSVVLPLKALLLNVLSLSAAFGALVWIFQEGHLGALGTTPTGTLVANMP 611 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VLLFCIAFGLSMDYEVFL+SRIRE+WL+SG R NDESVALG+ARTGRV Sbjct 612 VLLFCIAFGLSMDYEVFLMSRIREFWLKSGRTR----------QDNDESVALGLARTGRV 661 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 +TAAAL+M++SFAALIAA VSFMRMFG+G TLAV ADATL+RM++VPAFMH+ GRWNWWA Sbjct 662 VTAAALLMTISFAALIAAQVSFMRMFGVGFTLAVLADATLIRMLLVPAFMHLMGRWNWWA 721 Query 421 PRPLAWLHERFGVSEAAEP 439 P+PLA LHERFG+SE+AEP Sbjct 722 PKPLARLHERFGISESAEP 740 >gi|119868413|ref|YP_938365.1| MMPL domain-containing protein [Mycobacterium sp. KMS] gi|119694502|gb|ABL91575.1| MMPL domain protein [Mycobacterium sp. KMS] Length=754 Score = 566 bits (1460), Expect = 2e-159, Method: Compositional matrix adjust. Identities = 301/423 (72%), Positives = 350/423 (83%), Gaps = 10/423 (2%) Query 14 ITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVV 73 +TPAAI LLG R+DALDVRRL RRLL RP+P KPV++ FWYRS+KFVM R +PVG A + Sbjct 338 LTPAAIALLGDRIDALDVRRLGRRLLRRPEPAPKPVQRQFWYRSTKFVMHRAVPVGLAGI 397 Query 74 ALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP 133 A+L+LLGLPFL V+WG PDDRVLP+SASA +VGD LR +F DPAT + +V+PDARG Sbjct 398 AVLMLLGLPFLGVRWGLPDDRVLPQSASAHEVGDQLRTEFAADPATAVTVVIPDARGATE 457 Query 134 VELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRA 193 EL YA +LSRV DVS+V+APTGT+V G VG P ATG+ +GSAFLTVS+ APLFS + Sbjct 458 SELSRYATDLSRVADVSSVSAPTGTYVAGRRVGPPTAATGVRDGSAFLTVSTDAPLFSDS 517 Query 194 SDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGS 253 S QL+RLH+V GPAGR V +AGVA N DSV A+T RLP+VLGLIA T+ LLFLLT S Sbjct 518 SAAQLERLHEVTGPAGRPVELAGVAPSNSDSVAAITSRLPLVLGLIAVSTFCLLFLLTAS 577 Query 254 VVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD 313 VVLP KAL+ NVLSL+AAFGA+VWIFQEGH GALGTTP+GTLVAN+PVLLFCIAFGLSMD Sbjct 578 VVLPLKALLLNVLSLSAAFGAMVWIFQEGHLGALGTTPTGTLVANIPVLLFCIAFGLSMD 637 Query 314 YEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFA 373 YEVFL+SRIRE+WL SG R+ A+V ESVALG+ARTGRV+TAAALVMS+SFA Sbjct 638 YEVFLMSRIREFWLASG------RTAADVT----ESVALGLARTGRVVTAAALVMSISFA 687 Query 374 ALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGV 433 ALIAA+VSFMRMFGLGLTLAV ADATLVRMV+VPAFM V GRWNWW+P+PLA LH R G+ Sbjct 688 ALIAANVSFMRMFGLGLTLAVLADATLVRMVLVPAFMRVLGRWNWWSPKPLARLHRRIGL 747 Query 434 SEA 436 +EA Sbjct 748 AEA 750 >gi|108799297|ref|YP_639494.1| MMPL [Mycobacterium sp. MCS] gi|108769716|gb|ABG08438.1| MMPL [Mycobacterium sp. MCS] Length=748 Score = 566 bits (1459), Expect = 3e-159, Method: Compositional matrix adjust. Identities = 301/423 (72%), Positives = 350/423 (83%), Gaps = 10/423 (2%) Query 14 ITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVV 73 +TPAAI LLG R+DALDVRRL RRLL RP+P KPV++ FWYRS+KFVM R +PVG A + Sbjct 332 LTPAAIALLGDRIDALDVRRLGRRLLRRPEPAPKPVQRQFWYRSTKFVMHRAVPVGLAGI 391 Query 74 ALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGP 133 A+L+LLGLPFL V+WG PDDRVLP+SASA +VGD LR +F DPAT + +V+PDARG Sbjct 392 AVLMLLGLPFLGVRWGLPDDRVLPQSASAHEVGDQLRTEFAADPATAVTVVIPDARGATE 451 Query 134 VELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRA 193 EL YA +LSRV DVS+V+APTGT+V G VG P ATG+ +GSAFLTVS+ APLFS + Sbjct 452 SELSRYATDLSRVADVSSVSAPTGTYVAGRRVGPPTAATGVRDGSAFLTVSTDAPLFSDS 511 Query 194 SDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGS 253 S QL+RLH+V GPAGR V +AGVA N DSV A+T RLP+VLGLIA T+ LLFLLT S Sbjct 512 SAAQLERLHEVTGPAGRPVELAGVAPSNSDSVAAITSRLPLVLGLIAVSTFCLLFLLTAS 571 Query 254 VVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD 313 VVLP KAL+ NVLSL+AAFGA+VWIFQEGH GALGTTP+GTLVAN+PVLLFCIAFGLSMD Sbjct 572 VVLPLKALLLNVLSLSAAFGAMVWIFQEGHLGALGTTPTGTLVANIPVLLFCIAFGLSMD 631 Query 314 YEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFA 373 YEVFL+SRIRE+WL SG R+ A+V ESVALG+ARTGRV+TAAALVMS+SFA Sbjct 632 YEVFLMSRIREFWLASG------RTAADV----TESVALGLARTGRVVTAAALVMSISFA 681 Query 374 ALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGV 433 ALIAA+VSFMRMFGLGLTLAV ADATLVRMV+VPAFM V GRWNWW+P+PLA LH R G+ Sbjct 682 ALIAANVSFMRMFGLGLTLAVLADATLVRMVLVPAFMRVLGRWNWWSPKPLARLHRRIGL 741 Query 434 SEA 436 +EA Sbjct 742 AEA 744 >gi|240171559|ref|ZP_04750218.1| transmembrane transport protein MmpL13_1 [Mycobacterium kansasii ATCC 12478] Length=757 Score = 565 bits (1456), Expect = 6e-159, Method: Compositional matrix adjust. Identities = 281/455 (62%), Positives = 351/455 (78%), Gaps = 15/455 (3%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 +A V F A A++V+ P +VLLG RLDAL+VR+L RRL GRP+P +P+ Q FWYR++KF Sbjct 311 IAVVVFSALAAVVVAPTVLVLLGDRLDALNVRQLGRRLSGRPEPTRQPIAQSFWYRTAKF 370 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VMR +PVG A++ LL+ LG+PFL +KWG+PDDRVLP SASAR V D +R DF + AT+ Sbjct 371 VMRHAIPVGLAIITLLIALGIPFLGIKWGYPDDRVLPSSASARMVSDRIRSDFTSNSATR 430 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + IV+PD GL +LD+YAA+LS+VP+V+AV+APTG FV G G P G+A GSA+ Sbjct 431 VTIVIPDTAGLTTSDLDTYAAQLSQVPEVAAVSAPTGAFVAGRLTGPPSAPAGMAAGSAY 490 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV S APL+++AS+ QL RLH VA P G +V M G+AQ+NRD V+ +T RLP+V G IA Sbjct 491 LTVDSAAPLYTQASETQLDRLHAVALPGGHAVQMTGIAQMNRDCVNGITSRLPVVFGFIA 550 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 A+T VLLFL+TGS++LP KA++ N+LSLTAAFGALVWIFQ+GH GALGTTP+GTLVAN+P Sbjct 551 AVTVVLLFLMTGSLLLPIKAVLLNMLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANIP 610 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VL+FCIAFGLSMDYEVFL++RIREYWL+S AR A NDES+ALG+A TGRV Sbjct 611 VLMFCIAFGLSMDYEVFLLARIREYWLQSPRAR----------ADNDESIALGLAHTGRV 660 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAAL+MS+SFAALI+A VSFMRMFG+GLT+AV DATLVR ++VPAFMHV G NWWA Sbjct 661 ITAAALLMSISFAALISADVSFMRMFGVGLTIAVLVDATLVRALLVPAFMHVFGSLNWWA 720 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAG 455 P+PLA +H R E E AG +G+ G Sbjct 721 PQPLAAMHRRIFAGETGEA-----GEAGAVGEAVG 750 >gi|41408422|ref|NP_961258.1| hypothetical protein MAP2324c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396778|gb|AAS04641.1| hypothetical protein MAP_2324c [Mycobacterium avium subsp. paratuberculosis K-10] Length=784 Score = 560 bits (1444), Expect = 2e-157, Method: Compositional matrix adjust. Identities = 303/434 (70%), Positives = 349/434 (81%), Gaps = 6/434 (1%) Query 16 PAAIVLLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTA 71 PAAIVLLGPRLD +D RR++ R+L DP HKP+ + FWYRS+K+V+RR LPVG + Sbjct 330 PAAIVLLGPRLDTMDARRVMHRILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRALPVGLS 389 Query 72 VVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGL 131 VVALL+LLG+PFL VKWGFPD+RVLPRSASARQV D+L +DF T++ +VVPDARG+ Sbjct 390 VVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDNDF-PGLGTELSVVVPDARGV 448 Query 132 GPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFS 191 P EL YAAELSRVPDVSAV+APTGTF G VG P ATGLA GSAF TVSSTAPL+S Sbjct 449 TPTELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATGLANGSAFFTVSSTAPLYS 508 Query 192 RASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT 251 AS+ QL RLHQVAGP GR+V+M G+AQ+NRDSVDA+T RLP V GLIA +T++LLFLLT Sbjct 509 PASNAQLDRLHQVAGPGGRAVLMTGLAQINRDSVDAITKRLPTVFGLIAVVTFMLLFLLT 568 Query 252 GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS 311 GS VLP +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+ Sbjct 569 GSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA 628 Query 312 MDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMS 371 MDYEVFLVSRI EYWL S + R + E A DES ALG+A GRV+T AA+VMS+S Sbjct 629 MDYEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSIS 688 Query 372 FAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERF 431 FAALI AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPRP+ WL ER Sbjct 689 FAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERS 748 Query 432 GVSEAAE-PVSRRR 444 EA E V RRR Sbjct 749 ATGEAGEVRVGRRR 762 >gi|336460998|gb|EGO39878.1| putative RND superfamily drug exporter [Mycobacterium avium subsp. paratuberculosis S397] Length=781 Score = 560 bits (1443), Expect = 2e-157, Method: Compositional matrix adjust. Identities = 303/434 (70%), Positives = 349/434 (81%), Gaps = 6/434 (1%) Query 16 PAAIVLLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTA 71 PAAIVLLGPRLD +D RR++ R+L DP HKP+ + FWYRS+K+V+RR LPVG + Sbjct 327 PAAIVLLGPRLDTMDARRVMHRILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRALPVGLS 386 Query 72 VVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGL 131 VVALL+LLG+PFL VKWGFPD+RVLPRSASARQV D+L +DF T++ +VVPDARG+ Sbjct 387 VVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDNDF-PGLGTELSVVVPDARGV 445 Query 132 GPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFS 191 P EL YAAELSRVPDVSAV+APTGTF G VG P ATGLA GSAF TVSSTAPL+S Sbjct 446 TPTELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATGLANGSAFFTVSSTAPLYS 505 Query 192 RASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT 251 AS+ QL RLHQVAGP GR+V+M G+AQ+NRDSVDA+T RLP V GLIA +T++LLFLLT Sbjct 506 PASNAQLDRLHQVAGPGGRAVLMTGLAQINRDSVDAITKRLPTVFGLIAVVTFMLLFLLT 565 Query 252 GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS 311 GS VLP +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+ Sbjct 566 GSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA 625 Query 312 MDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMS 371 MDYEVFLVSRI EYWL S + R + E A DES ALG+A GRV+T AA+VMS+S Sbjct 626 MDYEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSIS 685 Query 372 FAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERF 431 FAALI AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPRP+ WL ER Sbjct 686 FAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERS 745 Query 432 GVSEAAE-PVSRRR 444 EA E V RRR Sbjct 746 ATGEAGEVRVGRRR 759 >gi|118472917|ref|YP_889424.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155] gi|118174204|gb|ABK75100.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155] Length=757 Score = 559 bits (1441), Expect = 3e-157, Method: Compositional matrix adjust. Identities = 296/425 (70%), Positives = 341/425 (81%), Gaps = 12/425 (2%) Query 15 TPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVA 74 TPAAIVLLG RLDA DVRR RR+ GRP+P KPV+Q FWYR++K MRR +P+G ++A Sbjct 329 TPAAIVLLGDRLDAYDVRRFFRRVFGRPEPEPKPVEQGFWYRTAKAAMRRAVPIGVGIIA 388 Query 75 LLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPV 134 LLVLLG+PF +KWGFPDDRVLP+SASARQ+GD +R +F D AT + +V+PDA + P Sbjct 389 LLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNFAVDSATSVTVVLPDATTVAPA 448 Query 135 ELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRAS 194 E+D YAA LS+V DVS+V+AP GT V G VG P ATG+ +GSAFLTV S APLFS AS Sbjct 449 EIDRYAARLSQVADVSSVSAPGGTDVQGRHVGPPSAATGIGDGSAFLTVGSDAPLFSDAS 508 Query 195 DIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSV 254 + QL LH VA A V GVAQVNRDS A+T RLP+VLG+IA IT+VLLFLLTGSV Sbjct 509 EAQLDALHAVAAHA--EVQFTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSV 566 Query 255 VLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDY 314 VLP KALV NVLSL+AAFGALVWIFQ+GH GALGTTP+GTLVAN+PVLLFCIAFGLSMDY Sbjct 567 VLPLKALVLNVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLSMDY 626 Query 315 EVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAA 374 EVFLVSRIRE+WL+S +R AAN+ESVALG+A TGRVITAAAL+MS+SFAA Sbjct 627 EVFLVSRIREFWLQSDQSR----------AANEESVALGLAHTGRVITAAALLMSISFAA 676 Query 375 LIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVS 434 LIAA V+FMRMFGLGLTLAV DATLVRM++VPAFM V GRWNWWAP PLA LHER G S Sbjct 677 LIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVPAFMRVMGRWNWWAPAPLARLHERIGFS 736 Query 435 EAAEP 439 E+ P Sbjct 737 ESGLP 741 >gi|254774486|ref|ZP_05216002.1| hypothetical protein MaviaA2_07423 [Mycobacterium avium subsp. avium ATCC 25291] Length=783 Score = 556 bits (1432), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 301/434 (70%), Positives = 349/434 (81%), Gaps = 6/434 (1%) Query 16 PAAIVLLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTA 71 PAAIVLLGPRLD +D RR++ R+L DP HKP+ + FWYRS+K+V+RR +PVG + Sbjct 329 PAAIVLLGPRLDTMDARRVMHRILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRAVPVGLS 388 Query 72 VVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGL 131 VVALL+LLG+PFL VKWGFPD+RVLPRSASARQV D+L +DF T++ +VVPDARG+ Sbjct 389 VVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDNDF-PGLGTELSVVVPDARGV 447 Query 132 GPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFS 191 P EL YAAELSRVPDVSAV+APTGTF G VG P ATGLA GSAF TVSSTAPL+S Sbjct 448 TPTELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATGLANGSAFFTVSSTAPLYS 507 Query 192 RASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT 251 AS+ QL RLHQVAGP GR+V+M G+AQ+NRDSV+A+T RLP V GLIA +T++LLFLLT Sbjct 508 PASNAQLDRLHQVAGPGGRAVLMTGLAQINRDSVEAITKRLPTVFGLIAVVTFMLLFLLT 567 Query 252 GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS 311 GS VLP +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+ Sbjct 568 GSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA 627 Query 312 MDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMS 371 MDYEVFLVSRI EYWL S + R + E A DES ALG+A GRV+T AA+VMS+S Sbjct 628 MDYEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSIS 687 Query 372 FAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERF 431 FAALI AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPRP+ WL ER Sbjct 688 FAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERS 747 Query 432 GVSEAAE-PVSRRR 444 EA E V RRR Sbjct 748 ATGEAGEVRVGRRR 761 >gi|118463097|ref|YP_880892.1| mmpl family protein [Mycobacterium avium 104] gi|118164384|gb|ABK65281.1| mmpl family protein [Mycobacterium avium 104] Length=784 Score = 556 bits (1432), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 301/434 (70%), Positives = 348/434 (81%), Gaps = 6/434 (1%) Query 16 PAAIVLLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTA 71 PAAIVLLGPRLD +D RR++ R+L DP HKP+ + FWYRS+K+V+RR +PVG + Sbjct 330 PAAIVLLGPRLDTMDARRVMHRILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRAVPVGLS 389 Query 72 VVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGL 131 VVALL+LLG+PFL VKWGFPD+RVLPRSASARQV D+L +DF T++ +VVPDARG+ Sbjct 390 VVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDNDF-PGLGTELSVVVPDARGV 448 Query 132 GPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFS 191 P EL YAAELSRVPDVSAV+APTGTF G VG P ATGLA GSAF TVSSTAPL+S Sbjct 449 TPAELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATGLANGSAFFTVSSTAPLYS 508 Query 192 RASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLT 251 AS+ QL RLHQVAGP GR+V M G+AQ+NRDSV+A+T RLP V GLIA +T++LLFLLT Sbjct 509 PASNAQLDRLHQVAGPGGRAVQMTGLAQINRDSVEAITKRLPTVFGLIAVVTFMLLFLLT 568 Query 252 GSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS 311 GS VLP +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+ Sbjct 569 GSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA 628 Query 312 MDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMS 371 MDYEVFLVSRI EYWL S + R + E A DES ALG+A GRV+T AA+VMS+S Sbjct 629 MDYEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSIS 688 Query 372 FAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERF 431 FAALI AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPRP+ WL ER Sbjct 689 FAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERS 748 Query 432 GVSEAAE-PVSRRR 444 EA E V RRR Sbjct 749 ATGEAGEVRVGRRR 762 >gi|145225715|ref|YP_001136393.1| MMPL domain-containing protein [Mycobacterium gilvum PYR-GCK] gi|145218201|gb|ABP47605.1| MMPL domain protein [Mycobacterium gilvum PYR-GCK] Length=743 Score = 554 bits (1427), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 292/431 (68%), Positives = 341/431 (80%), Gaps = 9/431 (2%) Query 19 IVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVL 78 + LLG RLD+LDV RL RR+L RP+PV PV+Q FWYR + VMRR LP+GT VV LL++ Sbjct 309 LALLGDRLDSLDVHRLARRVLRRPEPVPVPVEQRFWYRCATTVMRRALPLGTVVVVLLLV 368 Query 79 LGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF---GHDPATQIPIVVPDARGLGPVE 135 LG PFL VKWGFPD+RVLPRSASA QVGD LR +F ++ T + +VVPD+ GL P + Sbjct 369 LGAPFLGVKWGFPDERVLPRSASAHQVGDQLRAEFTGTANNVDTGVAVVVPDSAGLSPAD 428 Query 136 LDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASD 195 L +YAA LS+VPDV AV+APTGTFVDG+ G P G +GS FLTV+STAPLFS AS+ Sbjct 429 LSAYAAALSQVPDVPAVSAPTGTFVDGAQAGPPSAPAGERDGSTFLTVTSTAPLFSDASE 488 Query 196 IQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVV 255 QL RLH+V GP GR V M G AQ+NRDSVDA+T RLP+VLGLIA I + LLFLLTGSVV Sbjct 489 TQLDRLHEVPGPGGRDVQMTGTAQINRDSVDAITSRLPLVLGLIAIIMFALLFLLTGSVV 548 Query 256 LPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYE 315 +P KALV N+LSLTAAFGALVWIFQ+GH LGTTP+GTLVANMPVLLFCIAFGLSMDYE Sbjct 549 VPLKALVLNMLSLTAAFGALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGLSMDYE 608 Query 316 VFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAAL 375 VFLVSRIRE+ L+ A R + +ANDESVALG+A TGRVITAAAL+MS+SFAAL Sbjct 609 VFLVSRIREFRLQGHGGDTAGRKL----SANDESVALGIAHTGRVITAAALIMSISFAAL 664 Query 376 IAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSE 435 IAA+VSFMRMFGLGLTLAV DATLVRMV+VPAFMH+ G NWWAPR L +H R G S+ Sbjct 665 IAANVSFMRMFGLGLTLAVLVDATLVRMVLVPAFMHLMGGVNWWAPRFLTRIHRRLGFSD 724 Query 436 AAEPVSRRRSH 446 +P + +R+H Sbjct 725 --DPPTHQRAH 733 >gi|315446066|ref|YP_004078945.1| RND superfamily drug exporter [Mycobacterium sp. Spyr1] gi|315264369|gb|ADU01111.1| predicted RND superfamily drug exporter [Mycobacterium sp. Spyr1] Length=730 Score = 552 bits (1422), Expect = 5e-155, Method: Compositional matrix adjust. Identities = 289/428 (68%), Positives = 335/428 (79%), Gaps = 16/428 (3%) Query 19 IVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVL 78 + LLG RLD+LDV RL RR+L RP+PV PV+Q FWYR + VMRR LP+GT VV LL++ Sbjct 309 LALLGDRLDSLDVHRLARRVLRRPEPVPVPVEQRFWYRCATTVMRRALPLGTVVVVLLLV 368 Query 79 LGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDS 138 LG PFL VKWGFPD+RVLPRSASA QVGD LR +F + T + +VVPD+ GL P +L + Sbjct 369 LGAPFLGVKWGFPDERVLPRSASAHQVGDQLRTEFADNTDTGVAVVVPDSAGLSPADLSA 428 Query 139 YAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQL 198 YAA LS+VPDV AV+APTGTFVDG+ G P G +GS FLTV+STAPLFS AS+ QL Sbjct 429 YAAALSQVPDVPAVSAPTGTFVDGAQAGPPSAPAGERDGSTFLTVTSTAPLFSDASETQL 488 Query 199 KRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPA 258 RLH+V GP GR V M G AQ+NRDSVDA+T RLP+VLGLIA I + LLFLLTGSVV+P Sbjct 489 DRLHEVPGPGGRDVQMTGTAQINRDSVDAITSRLPLVLGLIAIIMFALLFLLTGSVVVPL 548 Query 259 KALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFL 318 KALV N+LSLTAAFGALVWIFQ+GH LGTTP+GTLVANMPVLLFCIAFGLSMDYEVFL Sbjct 549 KALVLNMLSLTAAFGALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGLSMDYEVFL 608 Query 319 VSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAA 378 VSRIRE+ L+ NDESVALG+A TGRVITAAAL+MS+SFAALIAA Sbjct 609 VSRIREFRLQG--------------HGNDESVALGIAHTGRVITAAALIMSISFAALIAA 654 Query 379 HVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAE 438 +VSFMRMFGLGLTLAV DATLVRMV+VPAFMH+ G NWWAPR L +H R G S+ + Sbjct 655 NVSFMRMFGLGLTLAVLVDATLVRMVLVPAFMHLMGGVNWWAPRFLTRIHRRLGFSD--D 712 Query 439 PVSRRRSH 446 P + +R+H Sbjct 713 PPTHQRAH 720 >gi|296170417|ref|ZP_06852005.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894888|gb|EFG74609.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=785 Score = 549 bits (1414), Expect = 5e-154, Method: Compositional matrix adjust. Identities = 291/431 (68%), Positives = 343/431 (80%), Gaps = 5/431 (1%) Query 19 IVLLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVA 74 I LLGPRLDALD R ++ R+L D HKP+++ FWYRS+++V+R LPVG +V+A Sbjct 330 IALLGPRLDALDARPILHRILHGQRSFRDHAHKPLEEQFWYRSTRYVLRHSLPVGLSVIA 389 Query 75 LLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPV 134 LL+LLG+PFL V+WGFPD+RVLPRSASARQV D+L DF + T + +VVP+ARG+ PV Sbjct 390 LLLLLGVPFLGVRWGFPDERVLPRSASARQVADMLDTDFANGLGTGVTVVVPNARGVTPV 449 Query 135 ELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRAS 194 +L+ YA+ LSRVPDVSAV APTGTFV G+ VG P AT LA G+AFL+V+STAPL+S AS Sbjct 450 DLERYASSLSRVPDVSAVTAPTGTFVAGNRVGPPAAATALANGAAFLSVASTAPLYSHAS 509 Query 195 DIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSV 254 ++QL RLH+V GPAGRSV M G+AQ+NRDSV+A+T RLP VL LIA +T+ LLFLLTGS Sbjct 510 NVQLDRLHKVPGPAGRSVEMTGLAQINRDSVNAITQRLPTVLVLIALVTFALLFLLTGSA 569 Query 255 VLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDY 314 VLP +ALVCNVLSLTAAFGA+VWIFQ+GH ALGTTP+GTL AN+PVLLFCIAFGL+MDY Sbjct 570 VLPLQALVCNVLSLTAAFGAMVWIFQDGHLNALGTTPNGTLNANIPVLLFCIAFGLAMDY 629 Query 315 EVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAA 374 EVFLVSRI EYWL S A + AE AA DES ALG+A GRV+T AALVMS+SFAA Sbjct 630 EVFLVSRIHEYWLASQAVEETPLTAAEARAATDESTALGIAGIGRVVTTAALVMSISFAA 689 Query 375 LIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVS 434 LI AHVSFMRM GLGLTLAV ADATLVRMV+VPAF+H GRW WWAP+PL L R Sbjct 690 LIPAHVSFMRMLGLGLTLAVLADATLVRMVLVPAFIHWLGRWTWWAPKPLERLRNRSVTG 749 Query 435 E-AAEPVSRRR 444 E AA V RRR Sbjct 750 ENAAAAVGRRR 760 >gi|342857903|ref|ZP_08714559.1| mmpl family protein [Mycobacterium colombiense CECT 3035] gi|342135236|gb|EGT88402.1| mmpl family protein [Mycobacterium colombiense CECT 3035] Length=792 Score = 543 bits (1399), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 300/431 (70%), Positives = 341/431 (80%), Gaps = 5/431 (1%) Query 19 IVLLGPRLDALDVRRLVRRLL--GRP--DPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVA 74 IVLLGPRLD +D RR++ R+L RP D HKP+ FWYRS+KFV+RR +PVG +VVA Sbjct 340 IVLLGPRLDTMDARRVMHRILHGQRPFRDHAHKPLVAQFWYRSTKFVLRRAMPVGLSVVA 399 Query 75 LLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPV 134 LL+LLG+PFL VKWGFPD+RVLPRSASARQV D+L DF + T + +VVPDA G+ P Sbjct 400 LLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDHDFANGLGTSVSVVVPDAHGVTPG 459 Query 135 ELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRAS 194 +L YAAELSRVPDVS V APTGTFV G+ VG P TGLA GSAFLTV STAPL+S+AS Sbjct 460 DLQRYAAELSRVPDVSGVTAPTGTFVAGNRVGPPAAPTGLANGSAFLTVDSTAPLYSQAS 519 Query 195 DIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSV 254 + QL RLHQV GPAGRSV M G+AQ+NRDSVDA+T RLP+V GLIA IT+ LLFLLTGSV Sbjct 520 NTQLDRLHQVGGPAGRSVQMTGLAQINRDSVDAITTRLPLVFGLIALITFALLFLLTGSV 579 Query 255 VLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDY 314 VLP +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+MDY Sbjct 580 VLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLAMDY 639 Query 315 EVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAA 374 EVFLVSRI EYW S A R + AE AA DES ALG+A GRV+T AA+VMS+SFAA Sbjct 640 EVFLVSRIHEYWQASQAVRETPPTPAEARAATDESTALGIAGIGRVVTTAAVVMSISFAA 699 Query 375 LIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVS 434 LI AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPR A L R Sbjct 700 LIPAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRWSALLRNRSATG 759 Query 435 E-AAEPVSRRR 444 E A V RRR Sbjct 760 EDEAVAVGRRR 770 >gi|120402584|ref|YP_952413.1| polyprenyl synthetase [Mycobacterium vanbaalenii PYR-1] gi|119955402|gb|ABM12407.1| Polyprenyl synthetase [Mycobacterium vanbaalenii PYR-1] Length=1155 Score = 536 bits (1382), Expect = 2e-150, Method: Compositional matrix adjust. Identities = 292/475 (62%), Positives = 341/475 (72%), Gaps = 33/475 (6%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPV-KQLFWYRSSK 59 +ATVA A A+IV+TPA I L G RLDA D+RR++RR P +P +Q+FWYRS+K Sbjct 339 LATVALCAVAAIVVTPAVIALFGDRLDAFDIRRMLRR-----TPAAEPRGEQMFWYRSTK 393 Query 60 FVMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPAT 119 FVMRR LPVG A ALLV LGLPFL V WG PDDRVLP SA+A +VGD+LR +F + Sbjct 394 FVMRRALPVGLAGTALLVSLGLPFLGVSWGLPDDRVLPSSATAHRVGDMLRTEFSDNSEA 453 Query 120 QIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSA 179 + ++VPDA GL P + + YAAE S + DVS V+APTGTF DG VG P G G+ G A Sbjct 454 AVTVLVPDAEGLTPQDFERYAAEASTIEDVSMVSAPTGTFADGRRVGPPAGGAGVQGGIA 513 Query 180 FLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLI 239 +LTV ST FS S+ QL RL + GP GR V M G+AQ+NRDSV+++ RLP+VLG+I Sbjct 514 YLTVGSTTASFSPESERQLDRLRALPGPGGRPVQMTGIAQINRDSVESIMARLPIVLGII 573 Query 240 AAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANM 299 A IT+VLLFLLTGS+VLP KALV N LSLTAAFGALVWIFQ+G+ GALGTTP+GTLV NM Sbjct 574 AVITFVLLFLLTGSLVLPVKALVLNALSLTAAFGALVWIFQDGNLGALGTTPTGTLVVNM 633 Query 300 PVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGR 359 PVLLFCIAFGLSMDYEVFL++RIRE+WL G RR NDESVALG+A TGR Sbjct 634 PVLLFCIAFGLSMDYEVFLLARIREFWLAGG-----RRD-------NDESVALGLAHTGR 681 Query 360 VITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWW 419 V+TAAAL+MS+SF ALIAA VSFMRMFGLGL LAV DATLVRMV++PAFMH+ GRWNWW Sbjct 682 VVTAAALIMSISFGALIAAQVSFMRMFGLGLMLAVLIDATLVRMVLLPAFMHLMGRWNWW 741 Query 420 APRPLA-WLHERFGVSEA-AEPVS---------RRRSHAG----GLGKIAGRSDG 459 AP PLA W R G +E A P RRR G G G R DG Sbjct 742 APAPLARWHARRTGTAEQNANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDG 796 Score = 37.0 bits (84), Expect = 8.5, Method: Compositional matrix adjust. Identities = 42/171 (25%), Positives = 73/171 (43%), Gaps = 32/171 (18%) Query 261 LVCNVLSLTAAFGALVWIFQEGHFGALGTTPSG-TLVANMPVLLF--------------- 304 L+ +++ F LVW+F+ AL G +VA+M VL Sbjct 206 LLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIVASMSVLRLVAMWTDVSIFALNLT 265 Query 305 -CIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITA 363 + L++DY + +VSR R+ E A P D ++ + GR + Sbjct 266 TALGLALAVDYTLLIVSRFRD---EVAAGAP-----------RDRALVTTMVTAGRTVLF 311 Query 364 AALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTG 414 +AL +++S AA++ + F++ F LA A + +VV PA + + G Sbjct 312 SALTVALSMAAMLLFPMYFLKSFAYA-GLATVALCAVAAIVVTPAVIALFG 361 >gi|120402209|ref|YP_952038.1| hypothetical protein Mvan_1197 [Mycobacterium vanbaalenii PYR-1] gi|119955027|gb|ABM12032.1| conserved hypothetical protein [Mycobacterium vanbaalenii PYR-1] Length=727 Score = 535 bits (1377), Expect = 1e-149, Method: Compositional matrix adjust. Identities = 288/418 (69%), Positives = 331/418 (80%), Gaps = 14/418 (3%) Query 19 IVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVL 78 ++LLG RLDALDV RL RR+L RP+P PV++ FWYR + VMRR LP+G AVV LL++ Sbjct 308 LMLLGDRLDALDVHRLARRILRRPEPTPTPVQRRFWYRCATTVMRRALPLGLAVVVLLLV 367 Query 79 LGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDS 138 LG PFL VKWGFPD+RVLP SAS+ QVGD LR DF + T + +VVPD+ GL P +L + Sbjct 368 LGAPFLGVKWGFPDERVLPPSASSHQVGDQLRRDFADNTDTAVTVVVPDSAGLSPADLSA 427 Query 139 YAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQL 198 YAAELSRVPDV AV+APTGTFVDG+ G P G + S FLTV+STAPLFS AS+ QL Sbjct 428 YAAELSRVPDVPAVSAPTGTFVDGARAGPPSAPAGEKDDSVFLTVASTAPLFSDASETQL 487 Query 199 KRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPA 258 RLH VAGP GR V+M G AQVNRDSVDA+T +LP+VLGLIA I + LLFLLTGS+V+P Sbjct 488 DRLHAVAGPGGREVLMTGTAQVNRDSVDAITSKLPIVLGLIAVIMFALLFLLTGSIVVPL 547 Query 259 KALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFL 318 KALV N+LSLTAAFGALVWIFQ+GH LGTTP+GTLVANMPVLLFCIAFGLSMDYEVFL Sbjct 548 KALVLNMLSLTAAFGALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGLSMDYEVFL 607 Query 319 VSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAA 378 VSRIRE+WLE+G +DESVALG+A TGRVITAAAL+MS+SFAALIAA Sbjct 608 VSRIREFWLETG--------------DSDESVALGIAHTGRVITAAALIMSISFAALIAA 653 Query 379 HVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEA 436 VSFMRMFGLGLTLAV DATLVRMV+VPAFMH+ G NWWAP L +HER G +EA Sbjct 654 SVSFMRMFGLGLTLAVLVDATLVRMVLVPAFMHLMGGLNWWAPGWLRRVHERLGFTEA 711 >gi|254823131|ref|ZP_05228132.1| mmpl family protein [Mycobacterium intracellulare ATCC 13950] Length=788 Score = 531 bits (1369), Expect = 8e-149, Method: Compositional matrix adjust. Identities = 282/422 (67%), Positives = 335/422 (80%), Gaps = 4/422 (0%) Query 21 LLGPRLDALDVRRLVRRLLGRP----DPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALL 76 LLGPRL LD RR++ R+L D H+P++ FWYRS+++V+R +P+G +VVALL Sbjct 335 LLGPRLHVLDARRVLHRILHGQRSFRDHAHQPLEDQFWYRSTRYVLRHAIPIGLSVVALL 394 Query 77 VLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVEL 136 +LLG PFL VKWGFPD+RVLP SASARQV D+L +DF + T++ +VVPDARG+ EL Sbjct 395 LLLGAPFLGVKWGFPDERVLPESASARQVADMLDNDFANGFGTEVSVVVPDARGVTLAEL 454 Query 137 DSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDI 196 YAA+LSRVPDVS+V+AP GTF +G+ VG P TG+A GSAFLTVS+TAPL+S+AS+ Sbjct 455 QRYAADLSRVPDVSSVSAPAGTFAEGNRVGPPVAPTGVANGSAFLTVSTTAPLYSQASNT 514 Query 197 QLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVL 256 QL RLHQVAGP GR+V M G+AQ+NRDSVDA+T RLP+V LIA IT+ LLFLLTGS VL Sbjct 515 QLDRLHQVAGPGGRAVQMTGLAQINRDSVDAITQRLPIVFALIALITFALLFLLTGSAVL 574 Query 257 PAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEV 316 P +ALVCNVLSLTAAFGA+VWIFQ+GH GALGTTP+GTL AN+PVLLFCIAFGL+ DYEV Sbjct 575 PLQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLATDYEV 634 Query 317 FLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALI 376 FLVSRI EYWL S A R + AE AA DES ALG+A GRV+T AA+VMS+SFAALI Sbjct 635 FLVSRIHEYWLASQAMRETPPTAAEARAATDESAALGIAGIGRVVTTAAVVMSISFAALI 694 Query 377 AAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEA 436 AHVSFMRM GLGLTL V DATLVRMV+VPAF+H+ GRW WWAPRPL L ER + E Sbjct 695 PAHVSFMRMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPLVSLRERSAIGED 754 Query 437 AE 438 E Sbjct 755 GE 756 >gi|183984778|ref|YP_001853069.1| transmembrane transport protein MmpL13_1 [Mycobacterium marinum M] gi|183178104|gb|ACC43214.1| conserved transmembrane transport protein MmpL13_1 [Mycobacterium marinum M] Length=769 Score = 527 bits (1357), Expect = 2e-147, Method: Compositional matrix adjust. Identities = 281/449 (63%), Positives = 341/449 (76%), Gaps = 10/449 (2%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VA VAF A A++V+ P IVLLG RLDAL+V +L RRLLGRP+P +PV Q FWYR++K Sbjct 311 VAVVAFSALAAMVVAPTVIVLLGDRLDALNVWKLGRRLLGRPEPPPRPVAQSFWYRTAKL 370 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 V R +PVG A++ LL+ LG+PFL++KWG+PDDRVLP SASAR V D +R DFG + A++ Sbjct 371 VTRHAIPVGLAIIVLLIALGIPFLNIKWGYPDDRVLPPSASARMVSDRIRSDFGSNSASR 430 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + +V+ D GL +L+ YAA+LS V DVSAV+APTGTFV G G P T +A GSA+ Sbjct 431 VTVVITDTAGLTKPDLNHYAAQLSEVSDVSAVSAPTGTFVAGELRGPPSAPTAMAAGSAY 490 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 LTV STAPL+++AS QL RLH VA P +V M GVAQ+NRDSV+ +T RLPMV G IA Sbjct 491 LTVESTAPLYTKASANQLDRLHAVALPGDTAVQMTGVAQMNRDSVNGITSRLPMVFGFIA 550 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 +T VLLFLLTGSV+LP KA+V N+LSLTAAFGALVWIFQ+GH GALGTTP+GTLVAN+P Sbjct 551 IVTLVLLFLLTGSVLLPIKAVVLNMLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANIP 610 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 VL+FCIAFGLSMDYEVFL+SRIRE+WL S + A NDES+ALG+A TGRV Sbjct 611 VLMFCIAFGLSMDYEVFLLSRIREFWLGS----------PQQSADNDESIALGLAHTGRV 660 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 ITAAAL+MS+SFA LI+A VSFMRMFG+GLT+AV DATLVR+++VPAFMHV G NWWA Sbjct 661 ITAAALLMSISFAGLISAEVSFMRMFGVGLTIAVLVDATLVRVLLVPAFMHVFGGLNWWA 720 Query 421 PRPLAWLHERFGVSEAAEPVSRRRSHAGG 449 P+PL H R G +A GG Sbjct 721 PKPLERWHSRSGADRSAGQTGPSDGAVGG 749 >gi|296165870|ref|ZP_06848353.1| mmpl family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898780|gb|EFG78303.1| mmpl family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=446 Score = 514 bits (1323), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 288/442 (66%), Positives = 336/442 (77%), Gaps = 3/442 (0%) Query 30 DVRRLVRRLLG---RPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSV 86 DVR L RLL R D HKP +FWYRS++FV+R + VG++VV LL+LLG+PFL V Sbjct 1 DVRPLAHRLLASTWRHDDAHKPAHSMFWYRSTRFVLRHAVAVGSSVVVLLLLLGVPFLGV 60 Query 87 KWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYAAELSRV 146 WGFPD+RVLPRSASARQV D+L + F D + +VVPD RG+ ++L+ YAA LS+V Sbjct 61 HWGFPDERVLPRSASARQVADLLDNQFTDDLGMAVSVVVPDTRGVSLLDLEHYAAALSQV 120 Query 147 PDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAG 206 PDVSAV APTGTFV G V P TG+A+G+AFLTV+ST PL+S+AS QL RLHQVA Sbjct 121 PDVSAVTAPTGTFVAGHRVSPPAAPTGIADGAAFLTVTSTVPLYSQASAAQLNRLHQVAT 180 Query 207 PAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVCNVL 266 PAGR V M+G+AQVNRDSVDA+T RLP LGLIA +T+VLLFLLTGSVVLP +ALVCNVL Sbjct 181 PAGRPVAMSGLAQVNRDSVDAITKRLPTALGLIALVTFVLLFLLTGSVVLPLQALVCNVL 240 Query 267 SLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYW 326 SLTAAFGA+VWIFQ+GH ALGTTP+GTL AN+P+LLFCIAFGL+MDYEVFLVSRIREYW Sbjct 241 SLTAAFGAMVWIFQDGHLRALGTTPNGTLNANIPMLLFCIAFGLAMDYEVFLVSRIREYW 300 Query 327 LESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMF 386 L S A S E AANDES ALG+A GRV+TAAALVMS+SFAALI A VSFMRM Sbjct 301 LASQTTLEAPPSPTEARAANDESTALGLAGIGRVVTAAALVMSISFAALIPAQVSFMRML 360 Query 387 GLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSH 446 GLGLTLAV ADATLVRM +VPAF+H+ G W+WWAP+PLAWLH+R EAA RR Sbjct 361 GLGLTLAVLADATLVRMFLVPAFIHLLGPWSWWAPKPLAWLHDRLTTGEAAAVAVGRRRW 420 Query 447 AGGLGKIAGRSDGQTIPASLTR 468 A + G + P L R Sbjct 421 ATDTSEPTADQAGASAPPKLNR 442 >gi|296167861|ref|ZP_06850044.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896986|gb|EFG76609.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=740 Score = 507 bits (1305), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 264/409 (65%), Positives = 313/409 (77%), Gaps = 14/409 (3%) Query 16 PAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVAL 75 P IVLLG RLDA DVR + RR RP V PV++ FWYR++K MR LPVG A++AL Sbjct 324 PTVIVLLGDRLDAFDVRNVGRRR--RPGSV--PVERTFWYRTAKLAMRHALPVGLAIIAL 379 Query 76 LVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVE 135 LV LG PF ++WG+PDDRVLP S+SAR V D +R DFG D A+ + +VV GL E Sbjct 380 LVALGAPFFGIRWGYPDDRVLPASSSARAVSDRIRQDFGTDSASTVRVVVARTGGLTARE 439 Query 136 LDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASD 195 L YAA LSRVPDV+AV+APTGTFV G G P GLA+GSA+LTV+STAPLFS ASD Sbjct 440 LGDYAARLSRVPDVAAVSAPTGTFVGGERTGPPSAPAGLADGSAYLTVASTAPLFSPASD 499 Query 196 IQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVV 255 QL RLH + P + + M G+AQ++RDSVDA+T RLP + G +A +T VLLF LTGSV+ Sbjct 500 AQLDRLHAIPPPGDQRIAMTGMAQMSRDSVDAITSRLPWLFGFVACVTLVLLFALTGSVL 559 Query 256 LPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYE 315 LP KA++ N+LSLTA FGALVWIFQ+GH GA+GTTP+GTLVA +PVL+FC+AFGLSMDYE Sbjct 560 LPVKAVLLNMLSLTAGFGALVWIFQDGHLGAMGTTPTGTLVATIPVLMFCVAFGLSMDYE 619 Query 316 VFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAAL 375 VFL+SRIREYWLES A NDES+ALGVARTGR+ITAAAL+MS+SFAAL Sbjct 620 VFLLSRIREYWLES----------PRTPADNDESIALGVARTGRIITAAALLMSISFAAL 669 Query 376 IAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPL 424 +A VSFMRMFG+GLTLAV DATLVRM++VPAFMHV GR NWWAP PL Sbjct 670 TSAGVSFMRMFGVGLTLAVLVDATLVRMLLVPAFMHVFGRLNWWAPAPL 718 >gi|169628380|ref|YP_001702029.1| MmpL family membrane protein [Mycobacterium abscessus ATCC 19977] gi|169240347|emb|CAM61375.1| Probable conserved membrane protein, MmpL family [Mycobacterium abscessus] Length=737 Score = 496 bits (1278), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 253/435 (59%), Positives = 325/435 (75%), Gaps = 10/435 (2%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKF 60 VA V A A++VI PA + LLG R+DALDVRRL+RR+LGRP+PV K V Q FWYR++K Sbjct 313 VAVVFVGAIAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKDVTQSFWYRTTKR 372 Query 61 VMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQ 120 VM R +P+ +V+ LV+LGLPFL K+GFPDDRVLP SASA QVG+ +R +F ++ +T Sbjct 373 VMARAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNFNNNSSTN 432 Query 121 IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAF 180 + ++ + P E+D YAA+LS + DV VAAPTG F+ G VG ATG+ +A Sbjct 433 LSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPSASATGIKNDTAL 492 Query 181 LTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIA 240 TV + A ++ A++ QL +H + GPA V + G AQ++RD+VD + +LP+VL +IA Sbjct 493 FTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLAIIA 552 Query 241 AITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMP 300 +T+VLLFLLTGSVVLP KALV NVLSLTA FGAL+WIFQEGH G GT +GT+VA MP Sbjct 553 VVTFVLLFLLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMP 612 Query 301 VLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV 360 +LLFCIAFGLSMDYEVFL+SRIREYW+ SG R A NDE+VALGVARTGRV Sbjct 613 MLLFCIAFGLSMDYEVFLISRIREYWMASGRTR----------ADNDEAVALGVARTGRV 662 Query 361 ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA 420 +TAAAL+M+++FAAL+AA VSFMRMFG GLT+A+ DAT++RM++VP+FM + GR+NWWA Sbjct 663 VTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNWWA 722 Query 421 PRPLAWLHERFGVSE 435 P+PL LHER G S+ Sbjct 723 PKPLVTLHERIGFSD 737 Score = 51.6 bits (122), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 81/322 (26%), Positives = 136/322 (43%), Gaps = 37/322 (11%) Query 97 PRSASARQVGDILRDDFGHDPATQ-IPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAP 155 P S SA V LRD F D + Q + ++ +G+ ++ + AA+L R S V Sbjct 47 PNSESA-YVTKALRDKF--DISDQSLVFMLTSEQGVKSPQMRAVAADLERQLKDSGVVIN 103 Query 156 TGTFVDGSWVGTPRGATGL--AEGSAFLTVSSTAPLFSRASDIQLKRLHQVA-GPAGRSV 212 + +W P+ A L A+G A L V+ + A K + +A G +V Sbjct 104 ----LTSAWTAPPQVAEELLGADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAV 159 Query 213 VMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAF 272 GVA + V L ++ + I++V+L + G + LV V S+ A Sbjct 160 KAGGVATLYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAM 219 Query 273 GALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAA 332 L G T N+ V + L++DY + ++SR RE E A Sbjct 220 SIL--------RGLTYVTDVSVFALNLAV---AMGLALAIDYSLLIISRYRE---EVNAG 265 Query 333 RPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTL 392 +P DE++ L + GR + +AL ++++ ALI + F++ FG + Sbjct 266 KP-----------RDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYA-GV 313 Query 393 AVAADATLVRMVVVPAFMHVTG 414 AV + +V+VPA + + G Sbjct 314 AVVFVGAIAALVIVPAVVTLLG 335 >gi|240168626|ref|ZP_04747285.1| integral membrane protein [Mycobacterium kansasii ATCC 12478] Length=754 Score = 495 bits (1274), Expect = 7e-138, Method: Compositional matrix adjust. Identities = 266/422 (64%), Positives = 322/422 (77%), Gaps = 9/422 (2%) Query 21 LLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLG 80 LLG RLDALD RR +RR+L RP P +P++Q FWYRSSK V+R +P+G A VALL+LLG Sbjct 336 LLGDRLDALDFRRFLRRVLRRPKPGQRPLEQFFWYRSSKIVLRYRIPIGLAAVALLLLLG 395 Query 81 LPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYA 140 PFL +WG+PDDRVLP SAS+RQVGD+LR DF D A I +V+P+A GL P +L YA Sbjct 396 APFLHARWGYPDDRVLPASASSRQVGDMLRSDFTDDNAKSIQVVIPEAAGLTPDQLGQYA 455 Query 141 AELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKR 200 A LS+V V V+AP GT+ DG VG P TG+A GSAFLTV+S APL+S SD QL Sbjct 456 AALSKVDGVLDVSAPQGTYTDGRAVGPPDAPTGVAGGSAFLTVNSKAPLYSHISDAQLDA 515 Query 201 LHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKA 260 LH V P R+V G+AQ NRDSVDA+ R+P VLG IAA+T+ LLFLLTGSVVLP KA Sbjct 516 LHAVPPPEARAVEFGGLAQTNRDSVDAIRARIPWVLGFIAAVTFTLLFLLTGSVVLPVKA 575 Query 261 LVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVS 320 ++ N +SLTA FGALVW+FQ+GH LGTT +GTLVAN+ VLLFCIAFGLSMDYEVFL++ Sbjct 576 VILNFMSLTAVFGALVWVFQDGHLAGLGTTSTGTLVANLAVLLFCIAFGLSMDYEVFLIA 635 Query 321 RIREYWLE----SGAARPARRSVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALI 376 RIREYW + + A PA R AAND+SV G+A TGRVITAAAL+M++SFAAL Sbjct 636 RIREYWSQLMRDASAMTPAAR-----RAANDDSVTRGLAHTGRVITAAALIMAISFAALT 690 Query 377 AAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHERFGVSEA 436 +A VSFMRMFGLGLT+AV DAT+VRM++VPAFM++ G+WNWWAP PLA LH+R G+ E+ Sbjct 691 SADVSFMRMFGLGLTIAVLVDATVVRMILVPAFMYLMGQWNWWAPAPLARLHQRVGIDES 750 Query 437 AE 438 A Sbjct 751 AS 752 >gi|315441958|ref|YP_004074837.1| RND superfamily drug exporter [Mycobacterium sp. Spyr1] gi|315260261|gb|ADT97002.1| predicted RND superfamily drug exporter [Mycobacterium sp. Spyr1] Length=731 Score = 473 bits (1217), Expect = 3e-131, Method: Compositional matrix adjust. Identities = 259/423 (62%), Positives = 312/423 (74%), Gaps = 18/423 (4%) Query 1 VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKP-VKQLFWYRSSK 59 VATV A A++V +PA +VLLG RL +RR R R D + V FW+RS++ Sbjct 315 VATVVLCAVAALVFSPALMVLLGDRL----MRRPGRH---RADGDGRDAVHHRFWFRSTQ 367 Query 60 FVMRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPAT 119 FV+R LPVG A ALLV GLPFL VKWG+PDDRVLP SASA QVGD LR+ F T Sbjct 368 FVLRHALPVGLAGSALLVCAGLPFLGVKWGYPDDRVLPASASAHQVGDQLREQFVGLSGT 427 Query 120 QIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSA 179 + +VVPDA G+ + + YA +LSRVPDV+AVAAP GTFVDG G +A+GSA Sbjct 428 ETTVVVPDASGISDADWERYATDLSRVPDVTAVAAPAGTFVDGRPAGPAAVGAEIADGSA 487 Query 180 FLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLGLI 239 +LTV+ +A LFS S++QL L V GP GR VVM G A VNRDS+D++ ++LP VLGL Sbjct 488 YLTVTGSAALFSAESEVQLADLKAVPGPGGRDVVMTGAAAVNRDSIDSIAEKLPTVLGLT 547 Query 240 AAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANM 299 AA+ +V+LF LT SVVLP KALV N LSLTAAFGALVWIFQ+GH GA GTTP+GTLVA + Sbjct 548 AAVIFVVLFALTRSVVLPLKALVLNGLSLTAAFGALVWIFQDGHLGAFGTTPTGTLVATI 607 Query 300 PVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGR 359 PVLLFCIAFGLSMDYEVFL++RIRE+WL SG RS A++ D SV LG+A TGR Sbjct 608 PVLLFCIAFGLSMDYEVFLLARIREFWLRSG------RSAADL----DRSVVLGLAYTGR 657 Query 360 VITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWW 419 V+TAAAL+M++SFA LIAA VSFMRMFG+GL LAV DATLVRMV++PA+M + GR+NWW Sbjct 658 VVTAAALIMTISFAGLIAAQVSFMRMFGVGLVLAVLVDATLVRMVLLPAYMKLLGRFNWW 717 Query 420 APR 422 APR Sbjct 718 APR 720 Lambda K H 0.324 0.137 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 994746070878 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40