BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1151c
Length=237
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608291|ref|NP_215667.1| NAD-dependent deacetylase [Mycobact... 479 1e-133
gi|340626164|ref|YP_004744616.1| putative transcriptional regula... 478 3e-133
gi|289573808|ref|ZP_06454035.1| transcriptional regulator [Mycob... 478 3e-133
gi|297730682|ref|ZP_06959800.1| NAD-dependent deacetylase [Mycob... 473 7e-132
gi|339294142|gb|AEJ46253.1| NAD-dependent deacetylase [Mycobacte... 468 4e-130
gi|183984272|ref|YP_001852563.1| transcriptional regulatory prot... 425 3e-117
gi|118616744|ref|YP_905076.1| NAD-dependent deacetylase [Mycobac... 423 1e-116
gi|296170037|ref|ZP_06851641.1| NAD-dependent deacetylase [Mycob... 420 7e-116
gi|15827795|ref|NP_302058.1| NAD-dependent deacetylase [Mycobact... 419 2e-115
gi|336458780|gb|EGO37740.1| NAD-dependent protein deacetylase, S... 418 4e-115
gi|41408731|ref|NP_961567.1| NAD-dependent deacetylase [Mycobact... 417 5e-115
gi|342861762|ref|ZP_08718408.1| NAD-dependent deacetylase [Mycob... 413 9e-114
gi|240172474|ref|ZP_04751133.1| NAD-dependent deacetylase [Mycob... 411 5e-113
gi|118462911|ref|YP_880534.1| NAD-dependent deacetylase [Mycobac... 407 8e-112
gi|254820693|ref|ZP_05225694.1| NAD-dependent deacetylase [Mycob... 405 2e-111
gi|254774165|ref|ZP_05215681.1| NAD-dependent deacetylase [Mycob... 400 6e-110
gi|118470343|ref|YP_889421.1| NAD-dependent deacetylase [Mycobac... 349 2e-94
gi|126436862|ref|YP_001072553.1| NAD-dependent deacetylase [Myco... 337 6e-91
gi|108801026|ref|YP_641223.1| NAD-dependent deacetylase [Mycobac... 337 7e-91
gi|333989777|ref|YP_004522391.1| transcriptional regulator [Myco... 335 2e-90
gi|145222722|ref|YP_001133400.1| NAD-dependent deacetylase [Myco... 315 4e-84
gi|120405522|ref|YP_955351.1| NAD-dependent deacetylase [Mycobac... 313 1e-83
gi|317508210|ref|ZP_07965891.1| Sir2 family protein [Segniliparu... 280 1e-73
gi|333921047|ref|YP_004494628.1| NAD-dependent deacetylase [Amyc... 278 7e-73
gi|296139039|ref|YP_003646282.1| silent information regulator pr... 247 1e-63
gi|312139005|ref|YP_004006341.1| nad-dependent deacetylase [Rhod... 244 1e-62
gi|325673717|ref|ZP_08153408.1| NAD-dependent deacetylase [Rhodo... 243 1e-62
gi|256824450|ref|YP_003148410.1| NAD-dependent protein deacetyla... 243 2e-62
gi|19551875|ref|NP_599877.1| NAD-dependent deacetylase [Coryneba... 239 3e-61
gi|343924706|ref|ZP_08764248.1| NAD-dependent deacetylase [Gordo... 235 5e-60
gi|262201930|ref|YP_003273138.1| silent information regulator pr... 232 4e-59
gi|169630522|ref|YP_001704171.1| NAD-dependent deacetylase [Myco... 231 6e-59
gi|289548029|ref|YP_003473017.1| silent information regulator pr... 231 9e-59
gi|296118332|ref|ZP_06836912.1| NAD-dependent deacetylase [Coryn... 230 2e-58
gi|319950841|ref|ZP_08024725.1| Silent information regulator pro... 229 3e-58
gi|239917161|ref|YP_002956719.1| NAD-dependent protein deacetyla... 227 9e-58
gi|163782393|ref|ZP_02177391.1| hypothetical protein HG1285_0638... 227 1e-57
gi|227831950|ref|YP_002833657.1| hypothetical protein cauri_0120... 226 3e-57
gi|93005287|ref|YP_579724.1| silent information regulator protei... 223 1e-56
gi|161485989|ref|NP_737263.2| NAD-dependent deacetylase [Coryneb... 223 1e-56
gi|23492490|dbj|BAC17463.1| putative cobalamin biosynthesis prot... 223 2e-56
gi|70729821|ref|YP_259560.1| NAD-dependent deacetylase [Pseudomo... 219 2e-55
gi|300780084|ref|ZP_07089940.1| NAD-dependent deacetylase [Coryn... 219 2e-55
gi|227487407|ref|ZP_03917723.1| Sir2 family NAD-dependent deacet... 218 4e-55
gi|227541152|ref|ZP_03971201.1| Sir2 family NAD-dependent deacet... 218 4e-55
gi|145592156|ref|YP_001154158.1| NAD-dependent deacetylase [Pyro... 218 5e-55
gi|309812451|ref|ZP_07706206.1| transcriptional regulator, Sir2 ... 218 6e-55
gi|119872305|ref|YP_930312.1| NAD-dependent deacetylase [Pyrobac... 217 1e-54
gi|227506094|ref|ZP_03936143.1| SIR2 family NAD-dependent deacet... 217 1e-54
gi|18314114|ref|NP_560781.1| NAD-dependent deacetylase [Pyrobacu... 217 1e-54
>gi|15608291|ref|NP_215667.1| NAD-dependent deacetylase [Mycobacterium tuberculosis H37Rv]
gi|15840591|ref|NP_335628.1| NAD-dependent deacetylase [Mycobacterium tuberculosis CDC1551]
gi|31792344|ref|NP_854837.1| NAD-dependent deacetylase [Mycobacterium bovis AF2122/97]
72 more sequence titles
Length=237
Score = 479 bits (1233), Expect = 1e-133, Method: Compositional matrix adjust.
Identities = 237/237 (100%), Positives = 237/237 (100%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV
Sbjct 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT
Sbjct 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA
Sbjct 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK
Sbjct 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
>gi|340626164|ref|YP_004744616.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
gi|340004354|emb|CCC43497.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
Length=237
Score = 478 bits (1230), Expect = 3e-133, Method: Compositional matrix adjust.
Identities = 236/237 (99%), Positives = 237/237 (100%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV
Sbjct 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT
Sbjct 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA
Sbjct 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLL+RLPALLK
Sbjct 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLKRLPALLK 237
>gi|289573808|ref|ZP_06454035.1| transcriptional regulator [Mycobacterium tuberculosis K85]
gi|339631216|ref|YP_004722858.1| transcriptional regulator [Mycobacterium africanum GM041182]
gi|289538239|gb|EFD42817.1| transcriptional regulator [Mycobacterium tuberculosis K85]
gi|339330572|emb|CCC26240.1| putative transcriptional regulatory protein [Mycobacterium africanum
GM041182]
Length=237
Score = 478 bits (1230), Expect = 3e-133, Method: Compositional matrix adjust.
Identities = 236/237 (99%), Positives = 237/237 (100%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV
Sbjct 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT
Sbjct 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
DALPEMPEPAIEVEPPVCDCGGLI+PDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA
Sbjct 121 DALPEMPEPAIEVEPPVCDCGGLIQPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK
Sbjct 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
>gi|297730682|ref|ZP_06959800.1| NAD-dependent deacetylase [Mycobacterium tuberculosis KZN R506]
gi|308398757|ref|ZP_07492814.2| transcriptional regulator [Mycobacterium tuberculosis SUMu012]
gi|308366631|gb|EFP55482.1| transcriptional regulator [Mycobacterium tuberculosis SUMu012]
Length=235
Score = 473 bits (1218), Expect = 7e-132, Method: Compositional matrix adjust.
Identities = 234/235 (99%), Positives = 235/235 (100%), Gaps = 0/235 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+AVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN
Sbjct 1 MAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 60
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA
Sbjct 61 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 120
Query 123 LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 182
LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV
Sbjct 121 LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 180
Query 183 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK
Sbjct 181 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 235
>gi|339294142|gb|AEJ46253.1| NAD-dependent deacetylase [Mycobacterium tuberculosis CCDC5079]
Length=243
Score = 468 bits (1203), Expect = 4e-130, Method: Compositional matrix adjust.
Identities = 231/232 (99%), Positives = 232/232 (100%), Gaps = 0/232 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+AVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN
Sbjct 1 MAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 60
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA
Sbjct 61 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 120
Query 123 LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 182
LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV
Sbjct 121 LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 180
Query 183 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPA 234
YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPA
Sbjct 181 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPA 232
>gi|183984272|ref|YP_001852563.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183177598|gb|ACC42708.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=238
Score = 425 bits (1093), Expect = 3e-117, Method: Compositional matrix adjust.
Identities = 208/237 (88%), Positives = 219/237 (93%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW RNPERVWGWYLWRHYLV
Sbjct 1 MRVTVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWERNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V PN GH+AIA WQDHAEVSV+TQNVDDLHERAGS VHHLHGSLFEFRCARC PYT
Sbjct 61 ADVAPNPGHQAIAEWQDHAEVSVVTQNVDDLHERAGSTPVHHLHGSLFEFRCARCNKPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
D+LP+MPEPA+EVEPPVC CGGLIRPDIVWFGEPLPE PW AVEAT +ADVMVVVGTSA
Sbjct 121 DSLPQMPEPALEVEPPVCGCGGLIRPDIVWFGEPLPEGPWHCAVEATEAADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLP+LALARG VIEVNPEPTPLS SAT+ +RESASQALPGLLERLPALL+
Sbjct 181 IVYPAAGLPELALARGKIVIEVNPEPTPLSRSATLCVRESASQALPGLLERLPALLR 237
>gi|118616744|ref|YP_905076.1| NAD-dependent deacetylase [Mycobacterium ulcerans Agy99]
gi|118568854|gb|ABL03605.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=238
Score = 423 bits (1087), Expect = 1e-116, Method: Compositional matrix adjust.
Identities = 207/237 (88%), Positives = 219/237 (93%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW RNPERVWGWYLWRHYLV
Sbjct 1 MRVTVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWERNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V PN GH+AIA WQDHAEVSV+TQNVDDLHERAGS VHHLHGSLFEFRCARC PYT
Sbjct 61 ADVAPNPGHQAIAEWQDHAEVSVVTQNVDDLHERAGSTPVHHLHGSLFEFRCARCNKPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
D+LP+MPEPA+EVEPPVC CGGLIRPDIVWFGEPLPE PW AVEAT +ADV+VVVGTSA
Sbjct 121 DSLPQMPEPALEVEPPVCGCGGLIRPDIVWFGEPLPEGPWHCAVEATEAADVVVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLP+LALARG VIEVNPEPTPLS SAT+ +RESASQALPGLLERLPALL+
Sbjct 181 IVYPAAGLPELALARGKIVIEVNPEPTPLSRSATLCVRESASQALPGLLERLPALLR 237
>gi|296170037|ref|ZP_06851641.1| NAD-dependent deacetylase [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295895305|gb|EFG75014.1| NAD-dependent deacetylase [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=237
Score = 420 bits (1080), Expect = 7e-116, Method: Compositional matrix adjust.
Identities = 206/237 (87%), Positives = 220/237 (93%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NPERVWGWYLWRHYLV
Sbjct 1 MRVTVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V+PN GHRAIAAWQD AEVSVITQNVDDLHERAGS VHHLHGSLFEFRC RCG+PYT
Sbjct 61 ADVQPNTGHRAIAAWQDGAEVSVITQNVDDLHERAGSVPVHHLHGSLFEFRCDRCGMPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LP+M EP +EVEPPVC CGGLIRPDIVWFGEPLP+EPW+SAVEAT +ADVMVVVGTSA
Sbjct 121 GTLPKMSEPTLEVEPPVCHCGGLIRPDIVWFGEPLPDEPWQSAVEATEAADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGL +LAL+RGTAVIEVNPE TPLS +ATISIRE+ASQALPGLL+RLPALL+
Sbjct 181 IVYPAAGLAELALSRGTAVIEVNPEVTPLSRNATISIRETASQALPGLLQRLPALLR 237
>gi|15827795|ref|NP_302058.1| NAD-dependent deacetylase [Mycobacterium leprae TN]
gi|221230272|ref|YP_002503688.1| NAD-dependent deacetylase [Mycobacterium leprae Br4923]
gi|38257887|sp|Q9CBW6.1|NPD_MYCLE RecName: Full=NAD-dependent deacetylase; AltName: Full=Regulatory
protein SIR2 homolog
gi|13093347|emb|CAC30462.1| conserved hypothetical protein [Mycobacterium leprae]
gi|219933379|emb|CAR71606.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=237
Score = 419 bits (1076), Expect = 2e-115, Method: Compositional matrix adjust.
Identities = 202/237 (86%), Positives = 217/237 (92%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV VLSGAGISAES VPTFRDDKNGLWARFDPY+LSSTQGW RNPERVWGWYLWRHYLV
Sbjct 1 MRVVVLSGAGISAESDVPTFRDDKNGLWARFDPYQLSSTQGWQRNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
ANV+PNDGHRAIAAWQ+ EVSVITQNVDDLHERAGS VHHLHGSLF+F CARC V YT
Sbjct 61 ANVKPNDGHRAIAAWQEQIEVSVITQNVDDLHERAGSTPVHHLHGSLFKFHCARCNVAYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
ALP+MPEP +EV+PPVC CGGLIRP IVWFGEPLP+EPWR AVEAT + DVMVVVGTSA
Sbjct 121 GALPDMPEPVLEVDPPVCYCGGLIRPAIVWFGEPLPDEPWRRAVEATETTDVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLP+LAL+RG VIEVNPEPTPL+ +ATISIRE+ASQALPGLL+RLPALLK
Sbjct 181 IVYPAAGLPELALSRGAVVIEVNPEPTPLTKNATISIRETASQALPGLLQRLPALLK 237
>gi|336458780|gb|EGO37740.1| NAD-dependent protein deacetylase, SIR2 family [Mycobacterium
avium subsp. paratuberculosis S397]
Length=253
Score = 418 bits (1074), Expect = 4e-115, Method: Compositional matrix adjust.
Identities = 204/237 (87%), Positives = 216/237 (92%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MR+AVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLV
Sbjct 17 MRIAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLV 76
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V PN GHRAIAAWQDHAEVSVITQNVDDLHERAGS VHHLHGSLFEFRCARC PYT
Sbjct 77 ADVAPNAGHRAIAAWQDHAEVSVITQNVDDLHERAGSRPVHHLHGSLFEFRCARCAKPYT 136
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LP M EPA+EV+PPVC CGGLIRPDIVWFGE LP+EPWR AVEAT SADVMVVVGTSA
Sbjct 137 GELPAMAEPALEVQPPVCGCGGLIRPDIVWFGEQLPDEPWRRAVEATESADVMVVVGTSA 196
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGL +LAL+RG AV+EVNPE TPLS SAT+SIRE+ASQALPGLL+RLPALL
Sbjct 197 IVYPAAGLAELALSRGAAVVEVNPEVTPLSASATLSIRETASQALPGLLQRLPALLN 253
>gi|41408731|ref|NP_961567.1| NAD-dependent deacetylase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|61213817|sp|Q73WM7.1|NPD_MYCPA RecName: Full=NAD-dependent deacetylase; AltName: Full=Regulatory
protein SIR2 homolog
gi|41397089|gb|AAS04950.1| hypothetical protein MAP_2633 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=237
Score = 417 bits (1073), Expect = 5e-115, Method: Compositional matrix adjust.
Identities = 204/237 (87%), Positives = 216/237 (92%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MR+AVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLV
Sbjct 1 MRIAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V PN GHRAIAAWQDHAEVSVITQNVDDLHERAGS VHHLHGSLFEFRCARC PYT
Sbjct 61 ADVAPNAGHRAIAAWQDHAEVSVITQNVDDLHERAGSRPVHHLHGSLFEFRCARCAKPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LP M EPA+EV+PPVC CGGLIRPDIVWFGE LP+EPWR AVEAT SADVMVVVGTSA
Sbjct 121 GELPAMAEPALEVQPPVCGCGGLIRPDIVWFGEQLPDEPWRRAVEATESADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGL +LAL+RG AV+EVNPE TPLS SAT+SIRE+ASQALPGLL+RLPALL
Sbjct 181 IVYPAAGLAELALSRGAAVVEVNPEVTPLSASATLSIRETASQALPGLLQRLPALLN 237
>gi|342861762|ref|ZP_08718408.1| NAD-dependent deacetylase [Mycobacterium colombiense CECT 3035]
gi|342130896|gb|EGT84192.1| NAD-dependent deacetylase [Mycobacterium colombiense CECT 3035]
Length=233
Score = 413 bits (1062), Expect = 9e-114, Method: Compositional matrix adjust.
Identities = 202/233 (87%), Positives = 218/233 (94%), Gaps = 0/233 (0%)
Query 5 VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVE 64
+LSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLVA+V+
Sbjct 1 MLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWHDNPQRVWGWYLWRHYLVADVQ 60
Query 65 PNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDALP 124
PN GHRAIAAWQD AEVSVITQNVDDLHERAGS +VHHLHGSLFEFRCARCGV Y+ ALP
Sbjct 61 PNAGHRAIAAWQDDAEVSVITQNVDDLHERAGSRSVHHLHGSLFEFRCARCGVGYSGALP 120
Query 125 EMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIVYP 184
MPEPA+EVEPPVC CGGLIRPDIVWFGE LP+EPW+ AVEAT +ADVMVVVGTSAIVYP
Sbjct 121 AMPEPALEVEPPVCHCGGLIRPDIVWFGEQLPDEPWQRAVEATEAADVMVVVGTSAIVYP 180
Query 185 AAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
AAGL +LAL+RGTAVIEVNPE TPLSGSATIS+RE+AS+ALPGLL+RLPALL
Sbjct 181 AAGLAELALSRGTAVIEVNPETTPLSGSATISMRETASRALPGLLQRLPALLN 233
>gi|240172474|ref|ZP_04751133.1| NAD-dependent deacetylase [Mycobacterium kansasii ATCC 12478]
Length=237
Score = 411 bits (1056), Expect = 5e-113, Method: Compositional matrix adjust.
Identities = 201/236 (86%), Positives = 215/236 (92%), Gaps = 0/236 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV VLSGAGISAESGVPTFRDDKNGLWARFDPYELSST GW NPERVWGWYLWRHYLV
Sbjct 1 MRVTVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTHGWESNPERVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A VEPN+GHRAIA WQ A+V+V+TQNVDDLHERAGS VHHLHGSLFEFRCARCG+PY+
Sbjct 61 ATVEPNEGHRAIADWQSAADVTVVTQNVDDLHERAGSAPVHHLHGSLFEFRCARCGIPYS 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
+ALP M EPAIEVEPPVC CGGLIRPDIVWFGE LPE PW+ AV AT SADVMVVVGTSA
Sbjct 121 EALPVMTEPAIEVEPPVCGCGGLIRPDIVWFGEALPEGPWQHAVAATESADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
IVYPAAGLP+LALARG VIEVNPEPTPLSGSATI +R+SAS+ALPGLL+RLP+LL
Sbjct 181 IVYPAAGLPELALARGIPVIEVNPEPTPLSGSATICVRQSASRALPGLLQRLPSLL 236
>gi|118462911|ref|YP_880534.1| NAD-dependent deacetylase [Mycobacterium avium 104]
gi|118164198|gb|ABK65095.1| NAD-dependent deacetylase [Mycobacterium avium 104]
Length=233
Score = 407 bits (1045), Expect = 8e-112, Method: Compositional matrix adjust.
Identities = 199/233 (86%), Positives = 212/233 (91%), Gaps = 0/233 (0%)
Query 5 VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVE 64
+LSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLVA+V
Sbjct 1 MLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLVADVA 60
Query 65 PNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDALP 124
PN GHRAIAAWQDHAEVSVITQNVDDLHERAGS VHHLHGSLFEFRCARC PYT LP
Sbjct 61 PNAGHRAIAAWQDHAEVSVITQNVDDLHERAGSRPVHHLHGSLFEFRCARCAKPYTGELP 120
Query 125 EMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIVYP 184
M EPA+EV+PPVC CGGLIRPDIVWFGE LP+EPWR AVEAT SADV+VVVGTSAIVYP
Sbjct 121 AMAEPALEVQPPVCGCGGLIRPDIVWFGEQLPDEPWRRAVEATESADVVVVVGTSAIVYP 180
Query 185 AAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
AAGL +LAL+RG AV+EVNPE TPLS SAT+SIRE+ASQALPGLL+RLPALL
Sbjct 181 AAGLAELALSRGAAVVEVNPEVTPLSASATLSIRETASQALPGLLQRLPALLN 233
>gi|254820693|ref|ZP_05225694.1| NAD-dependent deacetylase [Mycobacterium intracellulare ATCC
13950]
Length=237
Score = 405 bits (1042), Expect = 2e-111, Method: Compositional matrix adjust.
Identities = 207/237 (88%), Positives = 219/237 (93%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLV
Sbjct 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V+PN GHRAIAAWQD A V+VITQNVDDLHERAGSG+VHHLHGSLFEFRCARC PY+
Sbjct 61 ADVQPNAGHRAIAAWQDDARVTVITQNVDDLHERAGSGSVHHLHGSLFEFRCARCAEPYS 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
ALP MPEPA+EVEPPVC CGGLIRPDIVWFGE LP+EPWR AVEAT SADVMVVVGTSA
Sbjct 121 GALPHMPEPALEVEPPVCHCGGLIRPDIVWFGEQLPDEPWRRAVEATQSADVMVVVGTSA 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGL +LALARG AVIEVNPE TPLS +AT+SIRESASQALPGLL+RLPALL
Sbjct 181 IVYPAAGLAELALARGAAVIEVNPEVTPLSANATLSIRESASQALPGLLQRLPALLN 237
>gi|254774165|ref|ZP_05215681.1| NAD-dependent deacetylase [Mycobacterium avium subsp. avium ATCC
25291]
Length=238
Score = 400 bits (1029), Expect = 6e-110, Method: Compositional matrix adjust.
Identities = 202/238 (85%), Positives = 215/238 (91%), Gaps = 1/238 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MR+AVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGW NP+RVWGWYLWRHYLV
Sbjct 1 MRIAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLV 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A+V PN GHRAIAAWQDHAE SVITQNVDDLHERAGS VHHLHGSLFEFRCARC PYT
Sbjct 61 ADVAPNAGHRAIAAWQDHAEASVITQNVDDLHERAGSRPVHHLHGSLFEFRCARCAKPYT 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSAD-VMVVVGTS 179
LP M EPA+EV+PPVC CGGLIRPDIVWFGE LP+EPWR AVEAT SAD V+VVVGTS
Sbjct 121 GELPAMAEPALEVQPPVCGCGGLIRPDIVWFGEQLPDEPWRRAVEATESADVVVVVVGTS 180
Query 180 AIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
AIVYPAAGL +LAL+RG AV+EVNPE TPLS SAT+SIRE+ASQALPGLL+RLPALL
Sbjct 181 AIVYPAAGLAELALSRGAAVVEVNPEVTPLSASATLSIRETASQALPGLLQRLPALLN 238
>gi|118470343|ref|YP_889421.1| NAD-dependent deacetylase [Mycobacterium smegmatis str. MC2 155]
gi|118171630|gb|ABK72526.1| NAD-dependent deacetylase [Mycobacterium smegmatis str. MC2 155]
Length=240
Score = 349 bits (895), Expect = 2e-94, Method: Compositional matrix adjust.
Identities = 164/237 (70%), Positives = 193/237 (82%), Gaps = 0/237 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
M+V VLSGAGISAESGVPTFRD + GLWA+ DPYE+SST GW RNPE+VW WYLWRHY++
Sbjct 1 MQVTVLSGAGISAESGVPTFRDAETGLWAQVDPYEISSTDGWQRNPEKVWAWYLWRHYMM 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
A V PN+ HR +AAW+DH +V V+TQN+DDLHERAGS V+HLHGSLFEFRC CG +
Sbjct 61 ARVAPNEAHRTVAAWEDHLDVRVVTQNIDDLHERAGSTNVYHLHGSLFEFRCDACGSAFE 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LPEMPEP ++PPVC C GLIRP +VWFGEPLP+ W +V A SADV++VVGTS+
Sbjct 121 GNLPEMPEPVETIDPPVCPCSGLIRPSVVWFGEPLPDAAWNRSVLAVSSADVVIVVGTSS 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
IVYPAAGLP+ ALA G VIEVNPE TPLS SAT+S+RE+AS+ALP LL+RLP LL
Sbjct 181 IVYPAAGLPEAALAAGKPVIEVNPERTPLSDSATVSLRETASEALPTLLQRLPELLN 237
>gi|126436862|ref|YP_001072553.1| NAD-dependent deacetylase [Mycobacterium sp. JLS]
gi|126236662|gb|ABO00063.1| Silent information regulator protein Sir2 [Mycobacterium sp.
JLS]
Length=237
Score = 337 bits (865), Expect = 6e-91, Method: Compositional matrix adjust.
Identities = 166/236 (71%), Positives = 195/236 (83%), Gaps = 0/236 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
M+V VLSGAGISAESGVPTFRD + GLWA+ DPYE+SS GW NPE+VW WYLWRHY++
Sbjct 1 MQVTVLSGAGISAESGVPTFRDVETGLWAKVDPYEISSADGWRANPEKVWAWYLWRHYMM 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
V+PN+GH A+AAWQDHA+V V+TQNVDDLHERAGS V+HLHGSLFEF+C CG +
Sbjct 61 DAVQPNNGHHAVAAWQDHADVHVVTQNVDDLHERAGSRNVYHLHGSLFEFQCDACGSRFE 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LP MPEP V+PP C CGGLIRP++VWFGE LPE W+ +V A +ADV+VVVGTS+
Sbjct 121 GNLPAMPEPVEAVDPPQCPCGGLIRPNVVWFGEALPEAAWQHSVHAVLTADVVVVVGTSS 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
IVYPAAGLP++ALARGTAVIEVNPE TPLS SAT+S+RE+A ALP LL+RLP LL
Sbjct 181 IVYPAAGLPEMALARGTAVIEVNPERTPLSDSATVSLRETAVGALPTLLQRLPDLL 236
>gi|108801026|ref|YP_641223.1| NAD-dependent deacetylase [Mycobacterium sp. MCS]
gi|119870167|ref|YP_940119.1| NAD-dependent deacetylase [Mycobacterium sp. KMS]
gi|108771445|gb|ABG10167.1| Silent information regulator protein Sir2 [Mycobacterium sp.
MCS]
gi|119696256|gb|ABL93329.1| Silent information regulator protein Sir2 [Mycobacterium sp.
KMS]
Length=237
Score = 337 bits (865), Expect = 7e-91, Method: Compositional matrix adjust.
Identities = 166/236 (71%), Positives = 195/236 (83%), Gaps = 0/236 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
M+V VLSGAGISAESGVPTFRD + GLWA+ DPYE+SS GW NPE+VW WYLWRHY++
Sbjct 1 MQVTVLSGAGISAESGVPTFRDVETGLWAKVDPYEISSADGWRANPEKVWAWYLWRHYMM 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
V+PN+GH A+AAWQDHA+V V+TQNVDDLHERAGS V+HLHGSLFEF+C CG +
Sbjct 61 DAVQPNNGHHAVAAWQDHADVHVVTQNVDDLHERAGSRNVYHLHGSLFEFQCDACGSRFE 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LP MPEP V+PP C CGGLIRP++VWFGE LPE W+ +V A +ADV+VVVGTS+
Sbjct 121 GNLPAMPEPVEAVDPPQCPCGGLIRPNVVWFGEALPEAAWQRSVHAVLTADVVVVVGTSS 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
IVYPAAGLP++ALARGTAVIEVNPE TPLS SAT+S+RE+A ALP LL+RLP LL
Sbjct 181 IVYPAAGLPEMALARGTAVIEVNPERTPLSDSATVSLRETAVGALPTLLQRLPDLL 236
>gi|333989777|ref|YP_004522391.1| transcriptional regulator [Mycobacterium sp. JDM601]
gi|333485745|gb|AEF35137.1| transcriptional regulatory protein [Mycobacterium sp. JDM601]
Length=239
Score = 335 bits (860), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 160/236 (68%), Positives = 186/236 (79%), Gaps = 0/236 (0%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
M+VAV SGAGISAESGVPTFRDD+ GLW+++DPYE+SS GW R PE VWGWYLWR L
Sbjct 1 MQVAVFSGAGISAESGVPTFRDDEKGLWSQYDPYEVSSIDGWNRQPELVWGWYLWRCQLA 60
Query 61 ANVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
VEPN GHRA+A W+ HAEV VITQNVD+LHER GS VHHLHG +F FRC C P
Sbjct 61 RRVEPNLGHRAVADWEQHAEVHVITQNVDNLHERGGSSRVHHLHGRMFTFRCGDCDQPQD 120
Query 121 DALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
+P M EP +EV PPVC+CGGL+RPD+VWFGE LPEEPW +AVEA +ADV++VVGTS
Sbjct 121 PEVPVMTEPVLEVAPPVCECGGLVRPDVVWFGENLPEEPWNAAVEAIDNADVLIVVGTSG 180
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
+VYPAAGLP+ AL G VIEVNPEPTPLS AT +R +AS ALPG+++RLP LL
Sbjct 181 VVYPAAGLPERALELGKVVIEVNPEPTPLSERATTYLRTTASAALPGMVQRLPFLL 236
>gi|145222722|ref|YP_001133400.1| NAD-dependent deacetylase [Mycobacterium gilvum PYR-GCK]
gi|315443187|ref|YP_004076066.1| NAD-dependent protein deacetylase, SIR2 family [Mycobacterium
sp. Spyr1]
gi|145215208|gb|ABP44612.1| Silent information regulator protein Sir2 [Mycobacterium gilvum
PYR-GCK]
gi|315261490|gb|ADT98231.1| NAD-dependent protein deacetylase, SIR2 family [Mycobacterium
sp. Spyr1]
Length=236
Score = 315 bits (806), Expect = 4e-84, Method: Compositional matrix adjust.
Identities = 156/235 (67%), Positives = 194/235 (83%), Gaps = 1/235 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V SGAGISAESGVPTFRD + GLWA+ DPYE+SS GW +P+RVW WYLWRH++++
Sbjct 1 MTVFSGAGISAESGVPTFRDVETGLWAKVDPYEISSADGWRAHPDRVWAWYLWRHHMMSA 60
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
V PN+ HRA+AAW+D+A+V V+TQNVD+LHERAGS V+H+HGSLF+F C C Y
Sbjct 61 VGPNNAHRAVAAWEDYADVHVVTQNVDNLHERAGSRRVYHVHGSLFDFHCDTCRSAYRGP 120
Query 123 LPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAI 181
+P+MPEP V+PPVC+ CGGLIRPD+VWFGE LP++ W +VEA AD++VVVGTS++
Sbjct 121 VPDMPEPVESVDPPVCEACGGLIRPDVVWFGEALPDDAWERSVEAVAGADLVVVVGTSSV 180
Query 182 VYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
VYPAAGLP++ALA GT VIEVNPEPTPLS SAT+++RE AS ALPGLL+RLPALL
Sbjct 181 VYPAAGLPEMALANGTPVIEVNPEPTPLSSSATVTLREKASTALPGLLQRLPALL 235
>gi|120405522|ref|YP_955351.1| NAD-dependent deacetylase [Mycobacterium vanbaalenii PYR-1]
gi|119958340|gb|ABM15345.1| Silent information regulator protein Sir2 [Mycobacterium vanbaalenii
PYR-1]
Length=236
Score = 313 bits (802), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 155/235 (66%), Positives = 199/235 (85%), Gaps = 1/235 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V SGAG+SAESGVPTFRD + GLWA+ DPYE+SS GW +P+RVW WYLWRH++++
Sbjct 1 MTVFSGAGMSAESGVPTFRDVETGLWAKVDPYEISSADGWRAHPDRVWAWYLWRHHMMSA 60
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
V PN+ HRA+AAW+D+A+V V+TQNVD+LHERAGS V+H+HGSLFEF C RC + D
Sbjct 61 VAPNNAHRAVAAWEDYADVHVVTQNVDNLHERAGSSRVYHVHGSLFEFHCDRCRSTFPDK 120
Query 123 LPEMPEPAIEVEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAI 181
+P+MPEPA V PP C +CGGLIRP++VWFGEPLP++ W+ +V+A +AD++VVVGTS++
Sbjct 121 VPDMPEPAESVAPPSCGECGGLIRPNVVWFGEPLPDDAWQRSVDAVVNADLVVVVGTSSV 180
Query 182 VYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALL 236
VYPAAGLP+LA+A GT VIEVNPEPTPL+ SAT+S+RE+A+ ALPGLL+RLPALL
Sbjct 181 VYPAAGLPELAIAHGTPVIEVNPEPTPLTASATVSLRETAATALPGLLQRLPALL 235
>gi|317508210|ref|ZP_07965891.1| Sir2 family protein [Segniliparus rugosus ATCC BAA-974]
gi|316253500|gb|EFV12889.1| Sir2 family protein [Segniliparus rugosus ATCC BAA-974]
Length=241
Score = 280 bits (716), Expect = 1e-73, Method: Compositional matrix adjust.
Identities = 140/232 (61%), Positives = 161/232 (70%), Gaps = 1/232 (0%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
RV VLSGAG+SAESG+PTFR+ + GLW +FDP EL+S Q W +PE VW WYLWRH L
Sbjct 8 RVVVLSGAGMSAESGMPTFREAQTGLWEQFDPTELASPQAWRADPEFVWAWYLWRHELAR 67
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
PN GH AIA W+ AEV VITQNVDDLHERAGS V H+HGSLF FRCA C PY
Sbjct 68 RALPNAGHLAIAEWESRAEVVVITQNVDDLHERAGSSDVVHVHGSLFAFRCADCASPYDG 127
Query 122 ALPEMPEPAIEVEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
+P + P PP C CG +RP +VWFGE LPE PW AV A G A ++VVVGTS
Sbjct 128 QVPSVERPVARAAPPRCPRCGSAVRPGVVWFGEALPEAPWERAVRAVGEAALLVVVGTSG 187
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
+VYPAAGLP LA A G V+EVNPEP+ L+G +R A ALPGLL+RL
Sbjct 188 VVYPAAGLPALAKASGARVVEVNPEPSALTGEVDEFVRAKAGAALPGLLDRL 239
>gi|333921047|ref|YP_004494628.1| NAD-dependent deacetylase [Amycolicicoccus subflavus DQS3-9A1]
gi|333483268|gb|AEF41828.1| NAD-dependent deacetylase [Amycolicicoccus subflavus DQS3-9A1]
Length=251
Score = 278 bits (710), Expect = 7e-73, Method: Compositional matrix adjust.
Identities = 132/228 (58%), Positives = 165/228 (73%), Gaps = 1/228 (0%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
R+ VLSGAG+SAESG+PTFRD + GLW RFD L++ + W R+PE VW WY+WRH+LV
Sbjct 20 RITVLSGAGMSAESGLPTFRDAQTGLWERFDAAALATPEAWNRDPEFVWSWYMWRHHLVR 79
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
P+ GH A+A W+ A+V+++TQNVDDLHERAGS VHHLHGSLF FRCA+C Y+D
Sbjct 80 ATAPHAGHLAVAQWEHSADVTIVTQNVDDLHERAGSSHVHHLHGSLFHFRCAQCSFAYSD 139
Query 122 ALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
+ + PP C CGGLIRP +VWFGE LP EPW + V+A S DV+VVVGTS
Sbjct 140 EVDDSEPHESPRRPPRCQRCGGLIRPGVVWFGEMLPSEPWEAGVQAVDSCDVLVVVGTSG 199
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGL 228
+VYPAAGLP +A +G IE+NP+ TPLS T+S+R SA+ ALP L
Sbjct 200 LVYPAAGLPQIAHEKGIPTIEINPDETPLSRECTVSLRMSAATALPIL 247
>gi|296139039|ref|YP_003646282.1| silent information regulator protein Sir2 [Tsukamurella paurometabola
DSM 20162]
gi|296027173|gb|ADG77943.1| Silent information regulator protein Sir2 [Tsukamurella paurometabola
DSM 20162]
Length=273
Score = 247 bits (630), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 121/234 (52%), Positives = 156/234 (67%), Gaps = 7/234 (2%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ VL+GAG+SAESG+ TFR+ + GLWAR+DP E++S W R+ VWGWY WR Y+
Sbjct 30 IVVLTGAGMSAESGIATFREAQTGLWARYDPEEIASVDAWTRDSALVWGWYQWRGYIARQ 89
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
EPN+GH A+A VS++TQN+DDLHERAGS HLHGSLF RC CG PY +
Sbjct 90 AEPNNGHIALAELGTRRSVSIVTQNIDDLHERAGSEVTAHLHGSLFAPRCEYCGTPYLGS 149
Query 123 LPEM------PEPAIEVEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVV 175
E+ P P + V PP C C +RP IVWFGEPLP E W A A +AD+++V
Sbjct 150 DAEIRATDGEPTPEMRVTPPTCMQCLSQVRPGIVWFGEPLPMEAWGRAEAAVIAADLVLV 209
Query 176 VGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLL 229
+GTS +VYPAA LP++AL G V+E+NPEPTPLS AT++ +A+ LP L+
Sbjct 210 IGTSGLVYPAARLPEMALEAGIPVVEINPEPTPLSARATVAWNTTAATGLPALV 263
>gi|312139005|ref|YP_004006341.1| nad-dependent deacetylase [Rhodococcus equi 103S]
gi|311888344|emb|CBH47656.1| putative secreted NAD-dependent deacetylase [Rhodococcus equi
103S]
Length=277
Score = 244 bits (622), Expect = 1e-62, Method: Compositional matrix adjust.
Identities = 124/231 (54%), Positives = 149/231 (65%), Gaps = 1/231 (0%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
+V V SGAG+SAESG+PTFRD + GLW RF P +L+S +GW R+ VW WY WR LV
Sbjct 46 KVVVFSGAGMSAESGIPTFRDAQTGLWERFSPEQLASPEGWERDRGLVWAWYQWRTGLVR 105
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
V+PN GHRA+A W H V ++TQNVDDLHERAGS HLHGSLF RC CG P+
Sbjct 106 RVQPNAGHRAVAEWARHTPVEIVTQNVDDLHERAGSEVAAHLHGSLFAPRCGDCGAPHPS 165
Query 122 ALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
EP V PP C CGG +RP VWFGE LP + W A A D+MVVVGTS
Sbjct 166 DGGLDAEPTGPVAPPECTRCGGSVRPGAVWFGEALPVDAWERAENAVDECDLMVVVGTSG 225
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLER 231
+VYPAAGLP A+ G V+E+NP+ T LS S R +A++ LP L+ R
Sbjct 226 VVYPAAGLPLRAIGSGATVVEINPQATDLSPHVQYSWRTTAAEGLPALVAR 276
>gi|325673717|ref|ZP_08153408.1| NAD-dependent deacetylase [Rhodococcus equi ATCC 33707]
gi|325555738|gb|EGD25409.1| NAD-dependent deacetylase [Rhodococcus equi ATCC 33707]
Length=250
Score = 243 bits (621), Expect = 1e-62, Method: Compositional matrix adjust.
Identities = 124/231 (54%), Positives = 149/231 (65%), Gaps = 1/231 (0%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
+V V SGAG+SAESG+PTFRD + GLW RF P +L+S +GW R+ VW WY WR LV
Sbjct 19 KVVVFSGAGMSAESGIPTFRDAQTGLWERFSPEQLASPEGWERDRGLVWAWYQWRTGLVR 78
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
V+PN GHRA+A W H V ++TQNVDDLHERAGS HLHGSLF RC CG P+
Sbjct 79 RVQPNAGHRAVAEWARHTPVEIVTQNVDDLHERAGSEVAAHLHGSLFAPRCGDCGAPHPS 138
Query 122 ALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
EP V PP C CGG +RP VWFGE LP + W A A D+MVVVGTS
Sbjct 139 DGGLDAEPTGPVAPPECTRCGGSVRPGAVWFGEALPVDAWERAENAVDECDLMVVVGTSG 198
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLER 231
+VYPAAGLP A+ G V+E+NP+ T LS S R +A++ LP L+ R
Sbjct 199 VVYPAAGLPLRAIGSGATVVEINPQATDLSPHVQYSWRTTAAEGLPALVAR 249
>gi|256824450|ref|YP_003148410.1| NAD-dependent protein deacetylase, SIR2 family [Kytococcus sedentarius
DSM 20547]
gi|256687843|gb|ACV05645.1| NAD-dependent protein deacetylase, SIR2 family [Kytococcus sedentarius
DSM 20547]
Length=251
Score = 243 bits (620), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 126/234 (54%), Positives = 153/234 (66%), Gaps = 3/234 (1%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
RV VL+GAG SAESGVPTFRD GLWARFDP EL++ + W +P + W WY WR +LV
Sbjct 18 RVLVLTGAGASAESGVPTFRDAATGLWARFDPMELATPEAWAADPAQCWAWYAWRAHLVR 77
Query 62 NVEPNDGHRAIAAWQDH--AEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
EPN GHRAIAAWQ H ++ V TQNVD LHER+G+ + H+HG LF RCARCG
Sbjct 78 GAEPNAGHRAIAAWQQHEGVDLRVSTQNVDGLHERSGAEVLAHVHGDLFALRCARCGAAS 137
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
P +PEP +EPPVC CGGL+RP +VWFGE LP + V A A+++VVVGT
Sbjct 138 DAEYPPVPEPVERLEPPVCGRCGGLVRPGVVWFGEMLPAGALEATVTAAEWAEMVVVVGT 197
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
S +VYPAA +P +A G V+EVNP + L A I A QALP L+ L
Sbjct 198 SGMVYPAAAVPGIAREAGVPVVEVNPAGSSLPDGADHVIEAPAGQALPALVAAL 251
>gi|19551875|ref|NP_599877.1| NAD-dependent deacetylase [Corynebacterium glutamicum ATCC 13032]
gi|62389534|ref|YP_224936.1| NAD-dependent deacetylase [Corynebacterium glutamicum ATCC 13032]
gi|145294812|ref|YP_001137633.1| NAD-dependent deacetylase [Corynebacterium glutamicum R]
gi|38257866|sp|Q8NSM4.1|NPD_CORGL RecName: Full=NAD-dependent deacetylase; AltName: Full=Regulatory
protein SIR2 homolog
gi|21323409|dbj|BAB98037.1| NAD-dependent protein deacetylases, SIR2 family [Corynebacterium
glutamicum ATCC 13032]
gi|41324868|emb|CAF19350.1| protein deacetylase, SIR2 family [Corynebacterium glutamicum
ATCC 13032]
gi|140844732|dbj|BAF53731.1| hypothetical protein [Corynebacterium glutamicum R]
gi|344046006|gb|EGV41675.1| NAD-dependent deacetylase [Corynebacterium glutamicum S9114]
Length=258
Score = 239 bits (609), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 118/236 (50%), Positives = 156/236 (67%), Gaps = 4/236 (1%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V +GAG+SA+SG+ T+RDDK GLW+ DP ++S W ++PE +W WY WR + A
Sbjct 23 IEVFTGAGMSADSGLETYRDDKTGLWSNVDPQAMASIDAWRKDPEPMWAWYRWRAGVAAR 82
Query 63 VEPNDGHRAIAAWQ--DHAE-VSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
EPN GH+AI+ W+ D E V + TQN+D+LHERAGS V HLHGSLFE+RC+ C P+
Sbjct 83 AEPNAGHQAISYWEGSDTVEHVHITTQNIDNLHERAGSSDVTHLHGSLFEYRCSDCATPW 142
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
D EP + PP C+ CGGLIRP +VWFGE LP E W A + AD+M++VGT
Sbjct 143 EDDKNYPQEPIARLAPPQCEKCGGLIRPGVVWFGENLPVEEWDIAEQRIAEADLMIIVGT 202
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPA 234
S IV+PAA LP LA RG ++E++P T LS A + +A+QALP L+ L A
Sbjct 203 SGIVHPAAALPQLAQQRGVPIVEISPTRTELSRIADFTWMSTAAQALPALMRGLSA 258
>gi|343924706|ref|ZP_08764248.1| NAD-dependent deacetylase [Gordonia alkanivorans NBRC 16433]
gi|343765386|dbj|GAA11174.1| NAD-dependent deacetylase [Gordonia alkanivorans NBRC 16433]
Length=258
Score = 235 bits (599), Expect = 5e-60, Method: Compositional matrix adjust.
Identities = 125/238 (53%), Positives = 155/238 (66%), Gaps = 8/238 (3%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V SGAG+SAESG+ TFRD + GLW FDP EL++ + W R+P VWGWY WR V
Sbjct 20 ITVFSGAGVSAESGIATFRDVQTGLWETFDPAELATPEAWERDPALVWGWYRWRAREVLA 79
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT-- 120
EPN GHRA+A V V+TQNVDDLHERAGS V HLHGSLF RC+ C PY
Sbjct 80 AEPNTGHRALAELGASRTVMVVTQNVDDLHERAGSDVVSHLHGSLFAPRCSVCHTPYDGP 139
Query 121 DALPEMPEPAIE-----VEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMV 174
DA P +P E V PP C CGG +RP +VWFGE LP + W+ A +A +++V++
Sbjct 140 DARPSATDPDTEHVEPRVTPPTCPRCGGDVRPGVVWFGESLPTDDWQRADQAFRASEVVI 199
Query 175 VVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
VVGTS IVYPAA LP+ A+ G VIE NP + ++ AT S+R SA++ LP LL L
Sbjct 200 VVGTSGIVYPAASLPERAVREGIPVIEFNPAESSVTDFATHSLRVSAAEGLPALLRAL 257
>gi|262201930|ref|YP_003273138.1| silent information regulator protein sir2 [Gordonia bronchialis
DSM 43247]
gi|262085277|gb|ACY21245.1| Silent information regulator protein Sir2 [Gordonia bronchialis
DSM 43247]
Length=264
Score = 232 bits (591), Expect = 4e-59, Method: Compositional matrix adjust.
Identities = 128/241 (54%), Positives = 154/241 (64%), Gaps = 11/241 (4%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
V V +GAG+SAESG+ TFRD + GLW FDP +L++ + W R+P VWGWY WR V
Sbjct 23 VTVFTGAGMSAESGIATFRDARTGLWENFDPTDLATPEAWDRDPALVWGWYSWRARQVRA 82
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT-- 120
PN GH A+ V V+TQNVDDLHERAGS + HLHGSLF RCA CG PY
Sbjct 83 ARPNAGHLALVDLAGLRTVMVVTQNVDDLHERAGSEVISHLHGSLFAPRCAVCGRPYAPG 142
Query 121 DALPEMPEP----AI----EVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSAD 171
+L E P+ AI + PP C CGGL+RP IVWFGE LP + W A +A +D
Sbjct 143 PSLDEAPDTIGIDAIGDGGRIPPPSCSFCGGLVRPGIVWFGEALPAQAWERAEQAFRGSD 202
Query 172 VMVVVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLER 231
V++VVGTS IVYPAAGLP+ A G VIEVNPEP+ LS A I +A+ LPGL+ R
Sbjct 203 VVLVVGTSGIVYPAAGLPERAAREGIPVIEVNPEPSALSPIARHRIAMTAATGLPGLVRR 262
Query 232 L 232
L
Sbjct 263 L 263
>gi|169630522|ref|YP_001704171.1| NAD-dependent deacetylase [Mycobacterium abscessus ATCC 19977]
gi|169242489|emb|CAM63517.1| NAD-dependent deacetylase (regulatory protein Sir2 homolog) [Mycobacterium
abscessus]
Length=248
Score = 231 bits (590), Expect = 6e-59, Method: Compositional matrix adjust.
Identities = 113/216 (53%), Positives = 148/216 (69%), Gaps = 2/216 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
V VL+GAG+SAESG+PTFRD + GLW+++DP L++ + W +P VW WY R +
Sbjct 18 VTVLTGAGMSAESGLPTFRDAQTGLWSKYDPMTLATPESWQEDPGLVWAWYQNRRIQLLA 77
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
V+PNDGHRA+A W H ++ ++TQNVDDLHERAGS V H+HGSL + C C + +A
Sbjct 78 VQPNDGHRALAQWGSHRDIRIVTQNVDDLHERAGSSNVTHVHGSLLKSHCDTCRSDF-EA 136
Query 123 LPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 182
PE A V PP C CGG +RP IVWFGE LPE + AV + + D+M+++GTS IV
Sbjct 137 TVSAPE-AERVAPPECGCGGKVRPSIVWFGEMLPEVEFGHAVAHSQNCDLMLLIGTSGIV 195
Query 183 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIR 218
YPAAGLP LAL+RG V+E+NP+ T LS A + R
Sbjct 196 YPAAGLPQLALSRGATVVEINPQETDLSDRADLVWR 231
>gi|289548029|ref|YP_003473017.1| silent information regulator protein Sir2 [Thermocrinis albus
DSM 14484]
gi|289181646|gb|ADC88890.1| Silent information regulator protein Sir2 [Thermocrinis albus
DSM 14484]
Length=233
Score = 231 bits (588), Expect = 9e-59, Method: Compositional matrix adjust.
Identities = 121/237 (52%), Positives = 160/237 (68%), Gaps = 8/237 (3%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
MRV +L+GAG+SAESGVPTFR +GLW FDP +L++ Q + NP+ VW WY WR ++
Sbjct 1 MRVVILTGAGVSAESGVPTFRG-PSGLWRGFDPSKLATPQAFQENPKLVWEWYDWRRSII 59
Query 61 ANVEPNDGHRAIAAWQD-HAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
A EPN H IA ++ + +ITQNVD LH++AGS V LHG+++ RC CG Y
Sbjct 60 AKAEPNKAHLIIAQMEELFKDFILITQNVDGLHQKAGSRKVVELHGNIWMVRCLSCGDLY 119
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
D +PE PP C C GL+RP++VWFGE LPE+ R+A++ + S DVMVVVGT
Sbjct 120 EDRRVPLPEI-----PPHCRRCKGLVRPNVVWFGEALPEDALRTAIDWSQSCDVMVVVGT 174
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPAL 235
S +VYPAA LP LA RG VIEVNPEPTP+S A I++R+ AS+ + +LE+L +
Sbjct 175 SGVVYPAAHLPYLAAQRGATVIEVNPEPTPISSLAHITVRKPASEGMVEVLEKLKKM 231
>gi|296118332|ref|ZP_06836912.1| NAD-dependent deacetylase [Corynebacterium ammoniagenes DSM 20306]
gi|295968610|gb|EFG81855.1| NAD-dependent deacetylase [Corynebacterium ammoniagenes DSM 20306]
Length=246
Score = 230 bits (586), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 112/231 (49%), Positives = 157/231 (68%), Gaps = 2/231 (0%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
V +GAG+SA+SG+ TFRD + GLW + +P +++S + W R+PE +W WYLWR +L
Sbjct 16 HVHFFTGAGMSADSGLDTFRDAQTGLWQKVNPQDMASIEAWQRDPEPMWAWYLWRAHLAH 75
Query 62 NVEPNDGHRAIAAW-QDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
+P+ GH AI + Q ++VSV TQN+DDLHER+G V HLHGSL FRC+ C +PY
Sbjct 76 QSQPHAGHLAIGSLAQRSSQVSVTTQNIDDLHERSGCSDVAHLHGSLVAFRCSSCHLPYP 135
Query 121 DALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTS 179
+ +P + PP C+ CGGLIRP +VWFGE LP++ W A E +ADV+V+VGTS
Sbjct 136 HHIELPSKPVSRLRPPHCEECGGLIRPGVVWFGESLPQDQWEKAEENMRAADVVVIVGTS 195
Query 180 AIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLE 230
V+PAAGLP +A GT +IEV+P + L+ AT+ I ++A+ ALP +L+
Sbjct 196 GSVWPAAGLPSIAHRAGTPIIEVSPHRSDLTDLATVWIEDTAAAALPAILK 246
>gi|319950841|ref|ZP_08024725.1| Silent information regulator protein Sir2 [Dietzia cinnamea P4]
gi|319435496|gb|EFV90732.1| Silent information regulator protein Sir2 [Dietzia cinnamea P4]
Length=247
Score = 229 bits (584), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 117/228 (52%), Positives = 152/228 (67%), Gaps = 2/228 (0%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ VLSGAG+SAES VPTFRD + GLW R+DP L++++ W R+ + VW WY WR L+++
Sbjct 20 LVVLSGAGMSAESDVPTFRDAQTGLWERYDPAALATSEAWARDRDTVWAWYRWRENLISH 79
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
+PN GH A+A + +V V+TQNVDDLHERAGS VHH+HGSLF RC CG P D
Sbjct 80 AQPNAGHLAVARAAERRDVIVVTQNVDDLHERAGSPVVHHVHGSLFSHRCDTCGTPM-DV 138
Query 123 LPEMPEPAIEVEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAI 181
P + PP C CGG RP IVWFGE LP PW +V A A ++VVGTS +
Sbjct 139 GPPPVAAVGRLAPPHCIACGGRARPGIVWFGEMLPPGPWEESVAAIDRAAAVLVVGTSGL 198
Query 182 VYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLL 229
V+PAA LPDLA G V+EVNP P+ L+ + T+ +R +A +A+P +L
Sbjct 199 VHPAASLPDLAAEAGIPVVEVNPGPSGLAPAVTVHVRATAGEAVPEIL 246
>gi|239917161|ref|YP_002956719.1| NAD-dependent protein deacetylase, SIR2 family [Micrococcus luteus
NCTC 2665]
gi|281414369|ref|ZP_06246111.1| NAD-dependent protein deacetylase, SIR2 family [Micrococcus luteus
NCTC 2665]
gi|239838368|gb|ACS30165.1| NAD-dependent protein deacetylase, SIR2 family [Micrococcus luteus
NCTC 2665]
Length=306
Score = 227 bits (579), Expect = 9e-58, Method: Compositional matrix adjust.
Identities = 125/243 (52%), Positives = 154/243 (64%), Gaps = 16/243 (6%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
R VLSGAG+SAESG+PTFRD + GLW RF +L++ + +L +P VW WY WR +V
Sbjct 46 RPVVLSGAGMSAESGIPTFRDAQTGLWERFSAEQLATEEAFLADPALVWSWYRWRARMVR 105
Query 62 NVEPNDGHRAIAAWQDHA-EVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT 120
PN GH A+AAWQ ++ V+TQNVDDLHERAG+ + HLHGSLFE RCA CG P
Sbjct 106 ARRPNPGHDAVAAWQRRTPDLEVVTQNVDDLHERAGARVLAHLHGSLFEHRCAECGAP-A 164
Query 121 DALPEMP------------EPAIEVEPPVC-DCG-GLIRPDIVWFGEPLPEEPWRSAVEA 166
D P P E + PP C CG G IRP +VWFGE LP+EPW A EA
Sbjct 165 DVDPGAPSDVDAAGSEADLEAMLREAPPACPACGTGRIRPGVVWFGEMLPQEPWERAYEA 224
Query 167 TGSADVMVVVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALP 226
D+ +VVGTS ++ PAA LP +AL G AV+EVNP T LSG+ T ++R SA LP
Sbjct 225 LERCDLALVVGTSGLIQPAASLPFVALGAGVAVVEVNPVETELSGAVTHALRGSAGAVLP 284
Query 227 GLL 229
L+
Sbjct 285 ALV 287
>gi|163782393|ref|ZP_02177391.1| hypothetical protein HG1285_06385 [Hydrogenivirga sp. 128-5-R1-1]
gi|159882426|gb|EDP75932.1| hypothetical protein HG1285_06385 [Hydrogenivirga sp. 128-5-R1-1]
Length=228
Score = 227 bits (579), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 121/234 (52%), Positives = 156/234 (67%), Gaps = 8/234 (3%)
Query 1 MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV 60
M+V L+GAGISAESG+PTFR K+GLW ++ P EL++ + + RNPE VW WY WR L+
Sbjct 1 MKVVALTGAGISAESGIPTFRG-KDGLWNKYSPAELATPEAFSRNPELVWKWYDWRRQLI 59
Query 61 ANVEPNDGHRAIAAWQD-HAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
A EPNDGHR +A ++ + +ITQNVD LH+RAGS V LHG++++ RC RCG
Sbjct 60 AKAEPNDGHRTLAKMEELFPDFWLITQNVDGLHQRAGSKRVIELHGNIWKVRCVRCGEEG 119
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
D +PE PP C+ CGGL+RP +VWFGE LP + + A E ADV +VVGT
Sbjct 120 YDHRAPLPEI-----PPKCEKCGGLLRPGVVWFGESLPMDALQRAYELAEGADVFIVVGT 174
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
SA VYPAA LP + G +IEVNPE TP++ A +S+RESAS L +LE L
Sbjct 175 SAQVYPAAELPLITKRNGAKLIEVNPEETPITPHAYVSLRESASTGLKRVLEIL 228
>gi|227831950|ref|YP_002833657.1| hypothetical protein cauri_0120 [Corynebacterium aurimucosum
ATCC 700975]
gi|262183205|ref|ZP_06042626.1| NAD-dependent deacetylase [Corynebacterium aurimucosum ATCC 700975]
gi|227452966|gb|ACP31719.1| hypothetical protein cauri_0120 [Corynebacterium aurimucosum
ATCC 700975]
Length=247
Score = 226 bits (575), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 109/228 (48%), Positives = 150/228 (66%), Gaps = 4/228 (1%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
V V +GAG+SA+S + T+RD + G+W DP ++S W +P+ ++ WYLWR L
Sbjct 18 VEVFTGAGMSADSSIATYRDAQTGIWENVDPVAMASISAWRNDPKPMFAWYLWRAQLAQR 77
Query 63 VEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDA 122
PN GHRAIAA + ++V TQN+D+LHERAGS V HLHGSLF FRC C PY +
Sbjct 78 AAPNAGHRAIAAARG---MTVTTQNIDNLHERAGSQDVVHLHGSLFAFRCTDCDTPYDED 134
Query 123 LPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAI 181
+ EP + PP C CGGL+RP +VWFGE LP++ W A +AD +++VGTS +
Sbjct 135 IALPSEPVESITPPECPVCGGLVRPGVVWFGEALPDDEWAEAERRMSTADALLIVGTSGV 194
Query 182 VYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLL 229
VYPAAGLP +A ARG ++EV P+PT LS A + + +A+++LP +L
Sbjct 195 VYPAAGLPQIAHARGIPIVEVTPQPTDLSPLADVVVTATAAESLPRIL 242
>gi|93005287|ref|YP_579724.1| silent information regulator protein Sir2 [Psychrobacter cryohalolentis
K5]
gi|92392965|gb|ABE74240.1| Silent information regulator protein Sir2 [Psychrobacter cryohalolentis
K5]
Length=266
Score = 223 bits (569), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 115/243 (48%), Positives = 158/243 (66%), Gaps = 12/243 (4%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ +L+GAGISAESG+PTFRD + GLW + +L++ + R+P+ VW WY WR LVA+
Sbjct 26 ICLLTGAGISAESGIPTFRDKQTGLWENYRAEDLATPDAFARDPKLVWSWYQWRRQLVAS 85
Query 63 VEPNDGHRAIAAWQDHA-----EVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGV 117
+PN H A+A WQ H+ ++++ITQNVDDLHE+AGS AV HLHG+L+ RC++C
Sbjct 86 KKPNPAHTALAQWQYHSQSTNQQLTLITQNVDDLHEQAGS-AVTHLHGNLWRNRCSQCQT 144
Query 118 PYTDALPEM--PEPAIEVEPPV--CD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADV 172
PYT L E +I + + C C G IRPDIVWFGE LP W++A EA + DV
Sbjct 145 PYTIQLKSAYDSENSISFDEALMTCQHCDGYIRPDIVWFGESLPMRAWQTAEEAAANCDV 204
Query 173 MVVVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
+ +GTS++VYPAAGL LA G +IE+NP PTP + I++ A LP L++R+
Sbjct 205 FISIGTSSLVYPAAGLAQLAKHNGAKIIEINPYPTP-NTLVDITLAAKAGAILPELVKRM 263
Query 233 PAL 235
L
Sbjct 264 GIL 266
>gi|161485989|ref|NP_737263.2| NAD-dependent deacetylase [Corynebacterium efficiens YS-314]
gi|259506654|ref|ZP_05749556.1| NAD-dependent deacetylase [Corynebacterium efficiens YS-314]
gi|38258135|sp|Q8FRV5.2|NPD2_COREF RecName: Full=NAD-dependent deacetylase 2; AltName: Full=Regulatory
protein SIR2 homolog 2
gi|259165738|gb|EEW50292.1| NAD-dependent deacetylase [Corynebacterium efficiens YS-314]
Length=254
Score = 223 bits (569), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 113/234 (49%), Positives = 147/234 (63%), Gaps = 4/234 (1%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V +GAG+SA+SG+ T+RD + G+W++ DP ++S W R+PE +W WY WR
Sbjct 19 IEVFTGAGMSADSGLETYRDPETGVWSKVDPQAMASIDAWARDPEPMWAWYRWRAGQAMK 78
Query 63 VEPNDGHRAIAAWQDHA---EVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
PN GH IA W+ V V TQN+D+LHERAGS V HLHGSLFEFRC+ C P+
Sbjct 79 ARPNAGHETIAYWEGSHLVDAVHVTTQNIDNLHERAGSTEVTHLHGSLFEFRCSICSKPW 138
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
D EP + PP C CG +RP +VWFGE LP+E W A AD++V+VGT
Sbjct 139 RDDGDYPREPVERLAPPTCSLCGNPVRPGVVWFGEALPQEEWAVAERRMREADLVVIVGT 198
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
S IVYPAA LP LA RG ++E+ P+ T LS AT S R +A++ LP L+ RL
Sbjct 199 SGIVYPAASLPVLAHQRGVPILEITPKETDLSRIATYSWRATAAEGLPALVRRL 252
>gi|23492490|dbj|BAC17463.1| putative cobalamin biosynthesis protein [Corynebacterium efficiens
YS-314]
Length=314
Score = 223 bits (568), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 113/234 (49%), Positives = 147/234 (63%), Gaps = 4/234 (1%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
+ V +GAG+SA+SG+ T+RD + G+W++ DP ++S W R+PE +W WY WR
Sbjct 79 IEVFTGAGMSADSGLETYRDPETGVWSKVDPQAMASIDAWARDPEPMWAWYRWRAGQAMK 138
Query 63 VEPNDGHRAIAAWQDHA---EVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY 119
PN GH IA W+ V V TQN+D+LHERAGS V HLHGSLFEFRC+ C P+
Sbjct 139 ARPNAGHETIAYWEGSHLVDAVHVTTQNIDNLHERAGSTEVTHLHGSLFEFRCSICSKPW 198
Query 120 TDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
D EP + PP C CG +RP +VWFGE LP+E W A AD++V+VGT
Sbjct 199 RDDGDYPREPVERLAPPTCSLCGNPVRPGVVWFGEALPQEEWAVAERRMREADLVVIVGT 258
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
S IVYPAA LP LA RG ++E+ P+ T LS AT S R +A++ LP L+ RL
Sbjct 259 SGIVYPAASLPVLAHQRGVPILEITPKETDLSRIATYSWRATAAEGLPALVRRL 312
>gi|70729821|ref|YP_259560.1| NAD-dependent deacetylase [Pseudomonas fluorescens Pf-5]
gi|68344120|gb|AAY91726.1| NAD-dependent deacetylase [Pseudomonas fluorescens Pf-5]
Length=249
Score = 219 bits (559), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 111/233 (48%), Positives = 144/233 (62%), Gaps = 4/233 (1%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
V V SGAG+SAESG+PTFRD GLW FDP L++ Q + +P VWGWY WR V
Sbjct 14 VVVFSGAGVSAESGIPTFRDALTGLWEHFDPARLATVQAFREDPALVWGWYEWRRQKVLQ 73
Query 63 VEPNDGHRAIAAWQDHA-EVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
+PN H A+A +++ITQNVDDLHERAGS +V HLHGSL +C C P+
Sbjct 74 AQPNPAHLALAELARRVPRLTLITQNVDDLHERAGSPSVLHLHGSLHTPKCFACSRPFKG 133
Query 122 ALP--EMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGT 178
LP ++PE +EPP C C G IRP +VWFGEPLP+ ++A A D+++ VGT
Sbjct 134 QLPLPDLPEQGASLEPPRCTGCNGKIRPGVVWFGEPLPQATLKAAFNAAEECDLLLSVGT 193
Query 179 SAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLER 231
S +V PAA +P LAL G V+ +NP+P +G+ S+ A Q LP LL +
Sbjct 194 SGLVQPAARIPQLALQHGACVVHINPQPQACTGAEEYSLEGKAGQLLPELLRQ 246
>gi|300780084|ref|ZP_07089940.1| NAD-dependent deacetylase [Corynebacterium genitalium ATCC 33030]
gi|300534194|gb|EFK55253.1| NAD-dependent deacetylase [Corynebacterium genitalium ATCC 33030]
Length=263
Score = 219 bits (558), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 114/242 (48%), Positives = 152/242 (63%), Gaps = 14/242 (5%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
RV V +GAG+SA+SG+ T+RD G+W DP ++S W R+PE +W WYLWR L +
Sbjct 16 RVEVFTGAGMSADSGIATYRDAVTGVWENVDPQAMASIDAWARDPEPMWAWYLWRARLAS 75
Query 62 NVEPNDGHRAIAAW--QDHAEVSVITQNVDDLHERA-----------GSGAVHHLHGSLF 108
EPN GH AIA W ++ V+V TQN+D+LHERA + HLHGSLF
Sbjct 76 RAEPNAGHLAIAEWGRREGVRVTVTTQNIDNLHERAVLVNSTPDGPNNPDDIVHLHGSLF 135
Query 109 EFRCARCGVPYTDALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEAT 167
EFRC+ C PY + EP ++ PP C CG L+RP +VWFGEPLP + W A
Sbjct 136 EFRCSICSRPYKGEIELPEEPVEKLTPPSCPLCGNLVRPGVVWFGEPLPPKEWDEAERRM 195
Query 168 GSADVMVVVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPG 227
AD++V+VGTS +V+PAAGLP LA GT +IEV P T LS + +++ ++A++ALP
Sbjct 196 VEADLVVIVGTSGVVFPAAGLPLLAHELGTPIIEVTPMHTELSRISNVTLVDTAAKALPE 255
Query 228 LL 229
LL
Sbjct 256 LL 257
>gi|227487407|ref|ZP_03917723.1| Sir2 family NAD-dependent deacetylase [Corynebacterium glucuronolyticum
ATCC 51867]
gi|227092631|gb|EEI27943.1| Sir2 family NAD-dependent deacetylase [Corynebacterium glucuronolyticum
ATCC 51867]
Length=230
Score = 218 bits (556), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 108/232 (47%), Positives = 146/232 (63%), Gaps = 5/232 (2%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
+ +GAG+SA+SG+ T+RD + GLW DP L+S W ++PE ++ WY WR +
Sbjct 3 NIVFFTGAGMSADSGLTTYRDKETGLWENVDPTALASIDAWAKDPEPMFAWYTWRSLVSN 62
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
+VEPN GH +I A VITQN+D+LHER GS V HLHGSLF+++C CG PY+
Sbjct 63 SVEPNAGHVSIG----EAGYPVITQNIDNLHERGGSNEVVHLHGSLFKWKCTICGRPYSY 118
Query 122 ALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LPE EP + PP C CG IRP++ WFGE LPE+ W AVE + D +V+VGTS
Sbjct 119 TLPEWSEPVERLTPPTCPLCGNFIRPEVTWFGEALPEKAWNRAVELLQACDTLVIVGTSG 178
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
V PAA LP +AL G + E++P+ T L+ I ++A+ +P LLERL
Sbjct 179 TVQPAASLPLVALENGARLYEISPQTTSLTPLVHEFIEDTAASGVPELLERL 230
>gi|227541152|ref|ZP_03971201.1| Sir2 family NAD-dependent deacetylase [Corynebacterium glucuronolyticum
ATCC 51866]
gi|227183054|gb|EEI64026.1| Sir2 family NAD-dependent deacetylase [Corynebacterium glucuronolyticum
ATCC 51866]
Length=230
Score = 218 bits (556), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 108/232 (47%), Positives = 146/232 (63%), Gaps = 5/232 (2%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
++ +GAG+SA+SG+ T+RD + GLW + DP L+S W ++P+ ++ Y WR
Sbjct 3 KIVFFTGAGMSADSGLETYRDKETGLWEKVDPMALASIDSWAKDPDPMFAHYTWRSIASN 62
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD 121
N PN GH+AI VITQN+D+LHER GS V HLHGSLF+++C CG PY+
Sbjct 63 NATPNAGHKAIGTLG----APVITQNIDNLHERGGSAEVVHLHGSLFKWKCTICGRPYSY 118
Query 122 ALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSA 180
LPE+ EP + PP C CG IRP+I WFGE LPE+ W AVE DV+V+VGTS
Sbjct 119 TLPELTEPVERLTPPSCPLCGNPIRPEITWFGEALPEKAWNRAVELLQDCDVLVIVGTSG 178
Query 181 IVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
V PAA LP +AL G + E++P+PT L+ I ++A+ +P LLERL
Sbjct 179 TVQPAASLPLVALENGARLYEISPQPTSLTPLVHEFIEDTAASGVPALLERL 230
>gi|145592156|ref|YP_001154158.1| NAD-dependent deacetylase [Pyrobaculum arsenaticum DSM 13514]
gi|145283924|gb|ABP51506.1| Silent information regulator protein Sir2 [Pyrobaculum arsenaticum
DSM 13514]
Length=269
Score = 218 bits (555), Expect = 5e-55, Method: Compositional matrix adjust.
Identities = 117/234 (50%), Positives = 149/234 (64%), Gaps = 7/234 (2%)
Query 5 VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVE 64
V +GAGISAESGVPTFR GLW R+ P EL++ + + R+PE VW WY WR +V N
Sbjct 36 VFTGAGISAESGVPTFRG-LGGLWERYRPEELATPEAFARDPELVWRWYKWRQEVVYNAR 94
Query 65 PNDGHRAIAAWQDHAEV-SVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDAL 123
PN GH AIA + V +V+TQNVD LH+RAGS V LHGSL+ RC +CG Y
Sbjct 95 PNPGHMAIAELEALGVVKAVVTQNVDGLHQRAGSRRVVELHGSLWRTRCTKCGAVY---- 150
Query 124 PEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIVY 183
++ P EV P CGGL+RPD+VWFGEPLP + W AVE +DV++VVGTS +VY
Sbjct 151 -KLERPVDEVPPRCGKCGGLLRPDVVWFGEPLPRDAWNEAVELARISDVVLVVGTSGVVY 209
Query 184 PAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
PAA +P +A G VIE+N EP+ L+ A IR A + LP + E + L+
Sbjct 210 PAAYIPHIAKQGGAVVIEINVEPSALTPMADYFIRGRAGEVLPQIAEEVKKRLR 263
>gi|309812451|ref|ZP_07706206.1| transcriptional regulator, Sir2 family [Dermacoccus sp. Ellin185]
gi|308433756|gb|EFP57633.1| transcriptional regulator, Sir2 family [Dermacoccus sp. Ellin185]
Length=260
Score = 218 bits (555), Expect = 6e-55, Method: Compositional matrix adjust.
Identities = 110/212 (52%), Positives = 142/212 (67%), Gaps = 7/212 (3%)
Query 3 VAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVAN 62
V VL+GAG+S ESG+PTFRD GLW R DP EL++ W R+P+ VW WY WR L+ +
Sbjct 22 VVVLTGAGMSVESGIPTFRDAHTGLWERHDPEELATIDAWERDPDFVWAWYRWRAKLIRD 81
Query 63 VEPNDGHRAIAAWQD--HAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY- 119
V+PN GHRA+A W D A + ++TQN+DDLHERAGS + HLHGS+F RC+ C P+
Sbjct 82 VQPNVGHRALADWADAERANLWIVTQNIDDLHERAGSSVLAHLHGSIFALRCSECDTPFD 141
Query 120 --TDALPEMP-EPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVV 175
DA +P +P + PP C CG +RP +VWFGE LP+EP+ A A AD+++
Sbjct 142 EADDAALALPSDPVERLAPPRCPVCGAAVRPGVVWFGEELPQEPFAHAEAALERADLVLS 201
Query 176 VGTSAIVYPAAGLPDLALARGTAVIEVNPEPT 207
VGTS +V PAAGLP AL RG V+E+NP T
Sbjct 202 VGTSGVVQPAAGLPYRALTRGVPVVEINPAET 233
>gi|119872305|ref|YP_930312.1| NAD-dependent deacetylase [Pyrobaculum islandicum DSM 4184]
gi|119673713|gb|ABL87969.1| Silent information regulator protein Sir2 [Pyrobaculum islandicum
DSM 4184]
Length=251
Score = 217 bits (553), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 111/228 (49%), Positives = 149/228 (66%), Gaps = 7/228 (3%)
Query 6 LSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVEP 65
+GAGISAESGVPTFR GLW R+ P EL++ + + RNPE VW WY WR LV N +P
Sbjct 21 FTGAGISAESGVPTFRG-AGGLWERYKPEELATPEAFERNPELVWRWYRWRQELVYNAKP 79
Query 66 NDGHRAIAAWQDHAEV-SVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDALP 124
N GH A+A ++ + ++ITQNVD LH+RAGS V LHGSL+ RC +CG+ Y
Sbjct 80 NPGHLALAELENLGVIKAIITQNVDGLHQRAGSKNVVELHGSLWRARCVKCGLTY----- 134
Query 125 EMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIVYP 184
+ P E+ P +CGGL+RPD+VWFGEPLP++ W AVE +DV++V+GTS +VYP
Sbjct 135 RLERPVEEILPRCPNCGGLLRPDVVWFGEPLPQDVWNKAVELAHKSDVVLVIGTSGVVYP 194
Query 185 AAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERL 232
AA +P +A G VIE+N E + ++ A I I+ A LP L+ +
Sbjct 195 AAYIPHIAKRNGALVIEINTEESAITPIADIFIKGRAGVVLPALVREI 242
>gi|227506094|ref|ZP_03936143.1| SIR2 family NAD-dependent deacetylase [Corynebacterium striatum
ATCC 6940]
gi|227197376|gb|EEI77424.1| SIR2 family NAD-dependent deacetylase [Corynebacterium striatum
ATCC 6940]
Length=246
Score = 217 bits (553), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 106/234 (46%), Positives = 149/234 (64%), Gaps = 18/234 (7%)
Query 2 RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA 61
R+ + +GAG+SA+SG+ T+RD +G+W DP ++++ W ++P R+W WY R +
Sbjct 25 RIEIFTGAGMSADSGLATYRDPDSGIWENVDPQDMATIDAWAKDPIRMWRWYAHRRHQAE 84
Query 62 NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPY-- 119
+PN GH A+A W EV+V TQN+DDLHERAG+ V HLHGSLF FRC CG P+
Sbjct 85 KAQPNAGHIALAQWD--KEVTVTTQNIDDLHERAGTDDVVHLHGSLFAFRCCMCGRPWRG 142
Query 120 ---TDALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVV 176
TD PE P CG L+RP +VWFGE LP+ W A + +AD++++V
Sbjct 143 GVDTDTPPECPL-----------CGNLVRPGVVWFGEALPQREWEEAEKRMAAADLVIIV 191
Query 177 GTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLE 230
GTS +VYPAAGLP +A GT +IEV+P+ T L+ +T+ I +A+ ALP L+
Sbjct 192 GTSGVVYPAAGLPRIAHQLGTPIIEVSPQSTDLTSLSTVFINSTAADALPKLVN 245
>gi|18314114|ref|NP_560781.1| NAD-dependent deacetylase [Pyrobaculum aerophilum str. IM2]
gi|38258208|sp|Q8ZT00.1|NPD2_PYRAE RecName: Full=NAD-dependent deacetylase 2; AltName: Full=Regulatory
protein SIR2 homolog 2
gi|18161699|gb|AAL64963.1| conserved hypothetical protein [Pyrobaculum aerophilum str. IM2]
Length=249
Score = 217 bits (553), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 116/235 (50%), Positives = 155/235 (66%), Gaps = 9/235 (3%)
Query 5 VLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVE 64
V +GAGISAESGVPTFR GLW R+ P EL++ + + R+P VW WY WR ++ N
Sbjct 15 VFTGAGISAESGVPTFRGP-GGLWERYKPEELATPEAFARDPALVWRWYKWRQEVIYNAR 73
Query 65 PNDGHRAIAAWQDHAEV-SVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTDAL 123
P+ GH AIA + V VITQNVD LH+RAGS V LHGS++ RC +CG Y
Sbjct 74 PSPGHYAIAELEAMGVVRGVITQNVDGLHQRAGSRLVVELHGSIWRARCVKCGSVYI--- 130
Query 124 PEMPEPAIEVEPPVC-DCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIV 182
+ +P EV PP+C CGGL+RPD+VWFGEPLP+E WR+AVE +DV++VVGTS +V
Sbjct 131 --LDKPVEEV-PPLCRKCGGLLRPDVVWFGEPLPQEAWRAAVELASVSDVLLVVGTSGVV 187
Query 183 YPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 237
YPAA +P +A G V+E+N EP+ ++ A + I+ A + LP L+E + L+
Sbjct 188 YPAAYIPRIAKEAGARVVEINVEPSAITPIADVFIQGRAGEVLPRLVEEVKRRLR 242
Lambda K H
0.318 0.136 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 322714888716
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40