BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1153c
Length=282
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608293|ref|NP_215669.1| O-methyltransferase [Mycobacterium ... 564 6e-159
gi|340626166|ref|YP_004744618.1| putative O-methyltransferase OM... 562 2e-158
gi|31792346|ref|NP_854839.1| O-methyltransferase [Mycobacterium ... 560 9e-158
gi|240172472|ref|ZP_04751131.1| O-methyltransferase Omt_2 [Mycob... 436 2e-120
gi|183984270|ref|YP_001852561.1| O-methyltransferase Omt_2 [Myco... 417 7e-115
gi|118468855|ref|YP_889419.1| O-methyltransferase [Mycobacterium... 358 4e-97
gi|126436860|ref|YP_001072551.1| O-methyltransferase domain-cont... 358 7e-97
gi|333989778|ref|YP_004522392.1| O-methyltransferase Omt [Mycoba... 357 9e-97
gi|108801024|ref|YP_641221.1| O-methyltransferase-like protein [... 357 1e-96
gi|145222724|ref|YP_001133402.1| O-methyltransferase domain-cont... 322 3e-86
gi|145225833|ref|YP_001136511.1| O-methyltransferase domain-cont... 322 5e-86
gi|315442459|ref|YP_004075338.1| O-methyltransferase involved in... 321 8e-86
gi|120401994|ref|YP_951823.1| O-methyltransferase domain-contain... 319 3e-85
gi|120405520|ref|YP_955349.1| O-methyltransferase domain-contain... 313 2e-83
gi|108802193|ref|YP_642390.1| O-methyltransferase-like protein [... 307 1e-81
gi|183982739|ref|YP_001851030.1| O-methyltransferase Omt [Mycoba... 307 1e-81
gi|126438175|ref|YP_001073866.1| O-methyltransferase domain-cont... 306 3e-81
gi|296164975|ref|ZP_06847530.1| O-methyltransferase Omt [Mycobac... 306 3e-81
gi|118467412|ref|YP_890869.1| O-methyltransferase [Mycobacterium... 303 2e-80
gi|118618411|ref|YP_906743.1| O-methyltransferase Omt [Mycobacte... 297 1e-78
gi|169627771|ref|YP_001701420.1| O-methyltransferase OmT [Mycoba... 280 3e-73
gi|169628385|ref|YP_001702034.1| O-methyltransferase OMT [Mycoba... 274 1e-71
gi|169628388|ref|YP_001702037.1| O-methyltransferase OMT [Mycoba... 260 1e-67
gi|317506383|ref|ZP_07964193.1| O-methyltransferase [Segniliparu... 259 4e-67
gi|183980294|ref|YP_001848585.1| O-methyltransferase Omt_1 [Myco... 257 1e-66
gi|312199062|ref|YP_004019123.1| Leucine carboxyl methyltransfer... 249 4e-64
gi|118619892|ref|YP_908224.1| O-methyltransferase Omt_1 [Mycobac... 248 8e-64
gi|226362741|ref|YP_002780519.1| methyltransferase [Rhodococcus ... 238 9e-61
gi|300786085|ref|YP_003766376.1| O-methyltransferase OMT [Amycol... 233 3e-59
gi|340527552|gb|AEK42757.1| O-methyltransferase OMT [Amycolatops... 232 4e-59
gi|297159773|gb|ADI09485.1| O-methyltransferase OMT [Streptomyce... 218 1e-54
gi|345008735|ref|YP_004811089.1| methyltransferase [Streptomyces... 209 4e-52
gi|302543145|ref|ZP_07295487.1| putative O-methyltransferase [St... 208 7e-52
gi|296392751|ref|YP_003657635.1| O-methyltransferase domain-cont... 204 1e-50
gi|336118766|ref|YP_004573538.1| putative methyltransferase [Mic... 201 1e-49
gi|317509366|ref|ZP_07966986.1| O-methyltransferase [Segniliparu... 196 3e-48
gi|164690687|dbj|BAF98637.1| putative methyl transferase [Strept... 181 1e-43
gi|91779748|ref|YP_554956.1| putative O-methyltransferase [Burkh... 167 1e-39
gi|296161122|ref|ZP_06843932.1| O-methyltransferase domain prote... 167 2e-39
gi|294676967|ref|YP_003577582.1| O-methyltransferase domain-cont... 166 4e-39
gi|108756995|ref|YP_633338.1| putative O-methyltransferase [Myxo... 165 9e-39
gi|343919061|gb|EGV29816.1| O-methyltransferase domain-containin... 159 5e-37
gi|296445744|ref|ZP_06887697.1| phosphoribosylamine/glycine liga... 155 8e-36
gi|121609388|ref|YP_997195.1| O-methyltransferase domain-contain... 153 3e-35
gi|344343274|ref|ZP_08774143.1| putative O-methyltransferase [Ma... 152 4e-35
gi|113475372|ref|YP_721433.1| O-methyltransferase-like [Trichode... 150 2e-34
gi|114327547|ref|YP_744704.1| polyketide synthase O-methyltransf... 146 4e-33
gi|88705731|ref|ZP_01103441.1| Tetracenomycin polyketide synthes... 144 1e-32
gi|343492493|ref|ZP_08730856.1| O-methyltransferase-like protein... 142 5e-32
gi|296394826|ref|YP_003659710.1| O-methyltransferase domain-cont... 142 5e-32
>gi|15608293|ref|NP_215669.1| O-methyltransferase [Mycobacterium tuberculosis H37Rv]
gi|15840593|ref|NP_335630.1| O-methyltransferase, putative [Mycobacterium tuberculosis CDC1551]
gi|148660940|ref|YP_001282463.1| putative O-methyltransferase [Mycobacterium tuberculosis H37Ra]
71 more sequence titles
Length=282
Score = 564 bits (1453), Expect = 6e-159, Method: Compositional matrix adjust.
Identities = 281/282 (99%), Positives = 282/282 (100%), Gaps = 0/282 (0%)
Query 1 VSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT 60
+SAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT
Sbjct 1 MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT 60
Query 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI
Sbjct 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
Query 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA
Sbjct 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
Query 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD
Sbjct 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
Query 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG 282
LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
Sbjct 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG 282
>gi|340626166|ref|YP_004744618.1| putative O-methyltransferase OMT [Mycobacterium canettii CIPT
140010059]
gi|340004356|emb|CCC43499.1| putative O-methyltransferase OMT [Mycobacterium canettii CIPT
140010059]
Length=282
Score = 562 bits (1449), Expect = 2e-158, Method: Compositional matrix adjust.
Identities = 280/281 (99%), Positives = 281/281 (100%), Gaps = 0/281 (0%)
Query 1 VSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT 60
+SAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT
Sbjct 1 MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT 60
Query 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI
Sbjct 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
Query 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA
Sbjct 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
Query 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD
Sbjct 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
Query 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPAR 281
LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPAR
Sbjct 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPAR 281
>gi|31792346|ref|NP_854839.1| O-methyltransferase [Mycobacterium bovis AF2122/97]
gi|121637084|ref|YP_977307.1| putative O-methyltransferase omt [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224989557|ref|YP_002644244.1| putative O-methyltransferase [Mycobacterium bovis BCG str. Tokyo
172]
gi|31617934|emb|CAD94045.1| PROBABLE O-METHYLTRANSFERASE OMT [Mycobacterium bovis AF2122/97]
gi|121492731|emb|CAL71201.1| Probable O-methyltransferase omt [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224772670|dbj|BAH25476.1| putative O-methyltransferase [Mycobacterium bovis BCG str. Tokyo
172]
gi|341601100|emb|CCC63773.1| probable O-methyltransferase omt [Mycobacterium bovis BCG str.
Moreau RDJ]
Length=282
Score = 560 bits (1443), Expect = 9e-158, Method: Compositional matrix adjust.
Identities = 279/282 (99%), Positives = 280/282 (99%), Gaps = 0/282 (0%)
Query 1 VSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPT 60
+SAHKPAKQRVALTGVSETALLTLNARAAEARRRD IIDDPMAVALVESIDF FAKFGPT
Sbjct 1 MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDTIIDDPMAVALVESIDFGFAKFGPT 60
Query 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI
Sbjct 61 GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPI 120
Query 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA
Sbjct 121 VDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCA 180
Query 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD
Sbjct 181 QTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
Query 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG 282
LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
Sbjct 241 LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG 282
>gi|240172472|ref|ZP_04751131.1| O-methyltransferase Omt_2 [Mycobacterium kansasii ATCC 12478]
Length=278
Score = 436 bits (1122), Expect = 2e-120, Method: Compositional matrix adjust.
Identities = 216/274 (79%), Positives = 240/274 (88%), Gaps = 0/274 (0%)
Query 3 AHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQ 62
A + A+Q+V+LTGVSETALLTLNARAAEARR D II+DPMAV LV+SIDFDFAKFGPT Q
Sbjct 4 ADEAAQQKVSLTGVSETALLTLNARAAEARRSDPIIEDPMAVRLVDSIDFDFAKFGPTRQ 63
Query 63 GFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVD 122
ALRARAFD AA YL +HP+ATVVALAEGLQTSFWRLD A+ GQFRWLTVDL P++D
Sbjct 64 DIALRARAFDAAALSYLGRHPSATVVALAEGLQTSFWRLDAALSDGQFRWLTVDLEPVID 123
Query 123 LRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQT 182
+R RLLP+ RVSVCAQSALDYSWMD VDP+GGVFITAEGLLMYLQPEQAL LI++CAQ
Sbjct 124 IRARLLPTPARVSVCAQSALDYSWMDCVDPSGGVFITAEGLLMYLQPEQALALISECAQK 183
Query 183 FPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR 242
FPGGQMLFDLPPRWF +SRLG+RTSLRYK+P MPFS+SV QAADLVN VPG+ AVRD+
Sbjct 184 FPGGQMLFDLPPRWFTLFSRLGIRTSLRYKIPPMPFSLSVGQAADLVNTVPGIRAVRDVP 243
Query 243 VPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEF 276
+P GRGL N ALSTVYR+PVFD LRPCLTLLEF
Sbjct 244 LPTGRGLVFNAALSTVYRMPVFDALRPCLTLLEF 277
>gi|183984270|ref|YP_001852561.1| O-methyltransferase Omt_2 [Mycobacterium marinum M]
gi|183177596|gb|ACC42706.1| O-methyltransferase Omt_2 [Mycobacterium marinum M]
Length=278
Score = 417 bits (1073), Expect = 7e-115, Method: Compositional matrix adjust.
Identities = 214/274 (79%), Positives = 243/274 (89%), Gaps = 0/274 (0%)
Query 3 AHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQ 62
A + A+Q+VALTGVSETALLTLNARAAEARRRD II+DPMAV LV+SIDFDFAKFGPT Q
Sbjct 4 ADEFAQQKVALTGVSETALLTLNARAAEARRRDPIIEDPMAVRLVDSIDFDFAKFGPTRQ 63
Query 63 GFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVD 122
ALRA AFD A YL++HP+ATVVALAEGLQTSFWRLD A+PG +FRWLTVDLPPI+D
Sbjct 64 DIALRALAFDTRALAYLNKHPSATVVALAEGLQTSFWRLDSALPGKKFRWLTVDLPPIID 123
Query 123 LRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQT 182
+R RLLP+SPRVSVCAQSALDY WMDSVD +GGVFITAEGLLMYL+P+QAL LIAQCA+
Sbjct 124 IRKRLLPNSPRVSVCAQSALDYGWMDSVDTSGGVFITAEGLLMYLEPDQALDLIAQCAKR 183
Query 183 FPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR 242
FPG QMLFDLPPRWF+ ++RLG+RTS+RYK+P MPFS+SVAQAADLVN +PG+ AVRD++
Sbjct 184 FPGAQMLFDLPPRWFSLFTRLGMRTSIRYKIPPMPFSLSVAQAADLVNTIPGIRAVRDVQ 243
Query 243 VPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEF 276
+P GRGL N ALSTVYRLP D LRPCLTLLEF
Sbjct 244 LPAGRGLMFNAALSTVYRLPALDSLRPCLTLLEF 277
>gi|118468855|ref|YP_889419.1| O-methyltransferase [Mycobacterium smegmatis str. MC2 155]
gi|118170142|gb|ABK71038.1| O-methyltransferase, putative [Mycobacterium smegmatis str. MC2
155]
Length=278
Score = 358 bits (920), Expect = 4e-97, Method: Compositional matrix adjust.
Identities = 181/271 (67%), Positives = 211/271 (78%), Gaps = 1/271 (0%)
Query 7 AKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTG-QGFA 65
A+ RV+LTGVSETALLTL RA EARR D +I DPMAV LV+SIDFDFAKFG + Q A
Sbjct 7 ARTRVSLTGVSETALLTLQVRANEARRPDGLIKDPMAVQLVDSIDFDFAKFGHSHRQDMA 66
Query 66 LRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRT 125
LR+ FD A YL HP ATVVALAEGLQTSF+RL+ A G QF WLTVDLPP+V++R
Sbjct 67 LRSLIFDRATSDYLRDHPKATVVALAEGLQTSFYRLNEAGVGDQFCWLTVDLPPMVEIRN 126
Query 126 RLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPG 185
+LLP S RV CAQSALDYSWMD VD + GVFITAEGLLMYLQPE+++GLI +CA+ FPG
Sbjct 127 KLLPPSDRVRTCAQSALDYSWMDQVDDSEGVFITAEGLLMYLQPEESMGLIKECARRFPG 186
Query 186 GQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPP 245
GQM+FDLPP WFA W+R G+RTS RY+VP MPFS+S A+ ADLVN VPGV V DL PP
Sbjct 187 GQMIFDLPPSWFAAWARKGMRTSRRYRVPPMPFSLSPAEVADLVNTVPGVRVVHDLPFPP 246
Query 246 GRGLWVNMALSTVYRLPVFDPLRPCLTLLEF 276
RG ++ + V RLP+FDP+RP + LLEF
Sbjct 247 ARGKFMRTVVWGVQRLPLFDPIRPVMALLEF 277
>gi|126436860|ref|YP_001072551.1| O-methyltransferase domain-containing protein [Mycobacterium
sp. JLS]
gi|126236660|gb|ABO00061.1| O-methyltransferase domain protein [Mycobacterium sp. JLS]
Length=278
Score = 358 bits (918), Expect = 7e-97, Method: Compositional matrix adjust.
Identities = 182/266 (69%), Positives = 211/266 (80%), Gaps = 1/266 (0%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTG-QGFALRARA 70
ALTGVSETALLTL RA EARRRDA+IDDPMA+ LV+SIDFDF KFGP+ Q ALRA+
Sbjct 12 ALTGVSETALLTLQVRANEARRRDALIDDPMAIRLVDSIDFDFGKFGPSRRQDMALRAKG 71
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD + YL HP ATVVALAEGLQTSF RLD + G +FRWLTVDLPPIV+LRT+LLP
Sbjct 72 FDEYTRRYLSTHPRATVVALAEGLQTSFHRLDASGVGHEFRWLTVDLPPIVELRTKLLPP 131
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
S RV VCAQSALD++WMD VD + GVFITAEGLLMYLQP++A+ LI CAQ FPG QM+F
Sbjct 132 SERVRVCAQSALDFTWMDEVDDSEGVFITAEGLLMYLQPDEAMSLIRACAQRFPGAQMMF 191
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
DLPP WFA W+R G+RTSLRYKVP MPFS++ +AA L + VPG+ AV D+ +P GRG
Sbjct 192 DLPPSWFAWWARQGMRTSLRYKVPPMPFSLTPGEAAALADTVPGIRAVHDVPLPEGRGRV 251
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEF 276
+N L TV R+PVFD +RP TLLEF
Sbjct 252 LNALLWTVQRIPVFDAVRPVWTLLEF 277
>gi|333989778|ref|YP_004522392.1| O-methyltransferase Omt [Mycobacterium sp. JDM601]
gi|333485746|gb|AEF35138.1| O-methyltransferase Omt [Mycobacterium sp. JDM601]
Length=273
Score = 357 bits (917), Expect = 9e-97, Method: Compositional matrix adjust.
Identities = 179/268 (67%), Positives = 206/268 (77%), Gaps = 0/268 (0%)
Query 9 QRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRA 68
Q+V+LTGVSETALLTLNARA EARR D I++DPMAV L +SIDFDFAKFG T Q A+RA
Sbjct 5 QKVSLTGVSETALLTLNARATEARRPDRILNDPMAVRLADSIDFDFAKFGSTRQDIAVRA 64
Query 69 RAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLL 128
D AQ +L QHP TVVALAEGLQTSFWRL A+P QFRWLTVDLPPI+++R RLL
Sbjct 65 LGIDAQAQRFLRQHPTGTVVALAEGLQTSFWRLSEAVPDPQFRWLTVDLPPIIEIRQRLL 124
Query 129 PSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQM 188
P PRVSVC+QSALDYSWMD VD + GVFI+AEGLLMYLQPEQ+LGLIA+CA+ FPGG+M
Sbjct 125 PKEPRVSVCSQSALDYSWMDQVDNSEGVFISAEGLLMYLQPEQSLGLIAECARRFPGGRM 184
Query 189 LFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRG 248
+FDLPP W R G+ TSLRY+ P MPF++S A A LV+ VPG+ AV DL++P GRG
Sbjct 185 IFDLPPAWIGWLIRHGVPTSLRYRAPSMPFTLSAADTAKLVDTVPGIRAVHDLQLPRGRG 244
Query 249 LWVNMALSTVYRLPVFDPLRPCLTLLEF 276
N L YRL RP LTLLEF
Sbjct 245 WLFNTVLPNAYRLRSLADARPSLTLLEF 272
>gi|108801024|ref|YP_641221.1| O-methyltransferase-like protein [Mycobacterium sp. MCS]
gi|119870165|ref|YP_940117.1| O-methyltransferase domain-containing protein [Mycobacterium
sp. KMS]
gi|108771443|gb|ABG10165.1| O-methyltransferase-like protein [Mycobacterium sp. MCS]
gi|119696254|gb|ABL93327.1| O-methyltransferase domain protein [Mycobacterium sp. KMS]
Length=278
Score = 357 bits (916), Expect = 1e-96, Method: Compositional matrix adjust.
Identities = 182/266 (69%), Positives = 211/266 (80%), Gaps = 1/266 (0%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTG-QGFALRARA 70
ALTGVSETALLTL RA EARRRD +IDDPMA+ LV+SIDFDF KFGP+ Q ALRA+
Sbjct 12 ALTGVSETALLTLQVRANEARRRDGLIDDPMAIRLVDSIDFDFGKFGPSRRQDMALRAKG 71
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD + YL HP ATVVALAEGLQTSF RLD + G +FRWLTVDLPPIV+LRT+LLP
Sbjct 72 FDEYTRRYLRTHPRATVVALAEGLQTSFHRLDASGVGHEFRWLTVDLPPIVELRTKLLPP 131
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
S RV VCAQSALD++WMD VD + GVFITAEGLLMYLQP++A+ LI CAQ FPG QM+F
Sbjct 132 SERVRVCAQSALDFTWMDEVDDSEGVFITAEGLLMYLQPDEAMSLIRACAQRFPGAQMMF 191
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
DLPP WFA W+R G+RTSLRYKVP MPFS++ +AA LV+ VPG+ AV D+ +P GRG
Sbjct 192 DLPPSWFAWWARQGMRTSLRYKVPPMPFSLTPGEAAALVDTVPGIRAVHDVPLPEGRGRV 251
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEF 276
+N L TV R+PVFD +RP TLLEF
Sbjct 252 LNALLWTVQRIPVFDAVRPVWTLLEF 277
>gi|145222724|ref|YP_001133402.1| O-methyltransferase domain-containing protein [Mycobacterium
gilvum PYR-GCK]
gi|315443189|ref|YP_004076068.1| O-methyltransferase involved in polyketide biosynthesis [Mycobacterium
sp. Spyr1]
gi|145215210|gb|ABP44614.1| O-methyltransferase domain protein [Mycobacterium gilvum PYR-GCK]
gi|315261492|gb|ADT98233.1| O-methyltransferase involved in polyketide biosynthesis [Mycobacterium
sp. Spyr1]
Length=278
Score = 322 bits (826), Expect = 3e-86, Method: Compositional matrix adjust.
Identities = 172/272 (64%), Positives = 199/272 (74%), Gaps = 3/272 (1%)
Query 8 KQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTG-QGFAL 66
K LTGVSETAL+TL RA EARR D++IDDPMAV LV+S+DFD AKFG Q A+
Sbjct 6 KHSADLTGVSETALMTLLVRATEARRPDSLIDDPMAVKLVDSLDFDRAKFGFVRRQDMAV 65
Query 67 RARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIP--GGQFRWLTVDLPPIVDLR 124
RA FD + YL HP ATVVALAEGLQTSF+RLD G FRWLTVDLPP++DLR
Sbjct 66 RALVFDKWTRRYLVDHPRATVVALAEGLQTSFYRLDSGPESVGHDFRWLTVDLPPMIDLR 125
Query 125 TRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFP 184
T+LLP S RV AQSALD+SWMD VD + GVFITAEGLLMYLQP +A+ LI +CA FP
Sbjct 126 TKLLPPSDRVRTLAQSALDFSWMDQVDTSEGVFITAEGLLMYLQPAEAMSLITECAARFP 185
Query 185 GGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVP 244
GGQM+FDLPP FA G+R SLRY+VP MPFS+++A+AADLVN VPGV AV DL
Sbjct 186 GGQMIFDLPPSAFAFLVGRGVRASLRYRVPPMPFSLTIAEAADLVNTVPGVRAVHDLPAE 245
Query 245 PGRGLWVNMALSTVYRLPVFDPLRPCLTLLEF 276
RG +N L T R+P+ DP+RP TLLEF
Sbjct 246 HARGRLINALLWTAQRVPLLDPIRPMFTLLEF 277
>gi|145225833|ref|YP_001136511.1| O-methyltransferase domain-containing protein [Mycobacterium
gilvum PYR-GCK]
gi|145218319|gb|ABP47723.1| O-methyltransferase domain protein [Mycobacterium gilvum PYR-GCK]
Length=267
Score = 322 bits (824), Expect = 5e-86, Method: Compositional matrix adjust.
Identities = 164/265 (62%), Positives = 195/265 (74%), Gaps = 1/265 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGP-TGQGFALRARAF 71
L GVSETALLTLN RA +AR +AI+DDPMA+ +V+SIDFDF KFG GQ ALR+ AF
Sbjct 2 LAGVSETALLTLNGRAYQARHPNAILDDPMAIRVVDSIDFDFDKFGRRKGQEMALRSLAF 61
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D AA YL +HP ATVVALAEGLQTSFWRLD A+P +FRWLTVD PI++LR RLLP S
Sbjct 62 DRAATAYLAKHPKATVVALAEGLQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPES 121
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R++ AQSALDYSWMD+VD GVFITAEGLLMYLQPE+++GLI +CA FPG QM+FD
Sbjct 122 ARITTLAQSALDYSWMDAVDTTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQMIFD 181
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
LPP ++ G+R+S RY+VP MPFS+S A+ ADLV+ VPGV AV DL +P GRG +
Sbjct 182 LPPVMVKKFAPKGVRSSSRYRVPPMPFSLSAAELADLVHTVPGVRAVHDLPMPQGRGFFF 241
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
+ L R TLLEF
Sbjct 242 EKVFPAFWGLKATKNYRGAYTLLEF 266
>gi|315442459|ref|YP_004075338.1| O-methyltransferase involved in polyketide biosynthesis [Mycobacterium
sp. Spyr1]
gi|315260762|gb|ADT97503.1| O-methyltransferase involved in polyketide biosynthesis [Mycobacterium
sp. Spyr1]
Length=277
Score = 321 bits (823), Expect = 8e-86, Method: Compositional matrix adjust.
Identities = 164/265 (62%), Positives = 195/265 (74%), Gaps = 1/265 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGP-TGQGFALRARAF 71
L GVSETALLTLN RA +AR +AI+DDPMA+ +V+SIDFDF KFG GQ ALR+ AF
Sbjct 12 LAGVSETALLTLNGRAYQARHPNAILDDPMAIRVVDSIDFDFDKFGRRKGQEMALRSLAF 71
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D AA YL +HP ATVVALAEGLQTSFWRLD A+P +FRWLTVD PI++LR RLLP S
Sbjct 72 DRAATAYLAKHPKATVVALAEGLQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPES 131
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R++ AQSALDYSWMD+VD GVFITAEGLLMYLQPE+++GLI +CA FPG QM+FD
Sbjct 132 ARITTLAQSALDYSWMDAVDTTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQMIFD 191
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
LPP ++ G+R+S RY+VP MPFS+S A+ ADLV+ VPGV AV DL +P GRG +
Sbjct 192 LPPVMVKKFAPKGVRSSSRYRVPPMPFSLSAAELADLVHTVPGVRAVHDLPMPQGRGFFF 251
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
+ L R TLLEF
Sbjct 252 EKVFPAFWGLKATKNYRGAYTLLEF 276
>gi|120401994|ref|YP_951823.1| O-methyltransferase domain-containing protein [Mycobacterium
vanbaalenii PYR-1]
gi|119954812|gb|ABM11817.1| O-methyltransferase domain protein [Mycobacterium vanbaalenii
PYR-1]
Length=277
Score = 319 bits (818), Expect = 3e-85, Method: Compositional matrix adjust.
Identities = 165/266 (63%), Positives = 195/266 (74%), Gaps = 1/266 (0%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGP-TGQGFALRARA 70
AL GVSETALLTLN RA +AR +AIIDDPMA+ LV++IDFDF KFG GQ ALR+ A
Sbjct 11 ALAGVSETALLTLNGRAYQARHPNAIIDDPMAIRLVDAIDFDFDKFGRRKGQEMALRSLA 70
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD AA YL +HPAATVVALAEGLQTSFWRLD AIP +FRW+++DL P++ LR RLLP
Sbjct 71 FDRAATRYLSRHPAATVVALAEGLQTSFWRLDAAIPDSRFRWVSIDLEPVIALRRRLLPD 130
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
SPR++ AQSALDYSWMD+VD GVFITAEGLLMYLQP++A+ LI CA FPGGQM+F
Sbjct 131 SPRITTLAQSALDYSWMDAVDTTDGVFITAEGLLMYLQPDEAMDLITACASRFPGGQMIF 190
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
DLPP + G+R+S RY+VP MPFS+S AQ A+LV+ VPGV AV DL +P GRG
Sbjct 191 DLPPTMVKKIAPKGMRSSARYRVPPMPFSLSPAQLAELVHTVPGVTAVHDLPMPRGRGFL 250
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEF 276
++ R TLLEF
Sbjct 251 FERVFPAFWQFKPTRNYRGAYTLLEF 276
>gi|120405520|ref|YP_955349.1| O-methyltransferase domain-containing protein [Mycobacterium
vanbaalenii PYR-1]
gi|119958338|gb|ABM15343.1| O-methyltransferase domain protein [Mycobacterium vanbaalenii
PYR-1]
Length=306
Score = 313 bits (801), Expect = 2e-83, Method: Compositional matrix adjust.
Identities = 174/303 (58%), Positives = 204/303 (68%), Gaps = 30/303 (9%)
Query 4 HKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTG-Q 62
H +TGVSETALLTL RA EARR D++IDDPMA+ LV+SIDFDFAKFG Q
Sbjct 3 HTGKHTATDVTGVSETALLTLLVRATEARRPDSLIDDPMAIHLVDSIDFDFAKFGYVRRQ 62
Query 63 GFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIP--GGQFRWLTVDLPPI 120
+LRA AFD + YL HP ATVVALAEGLQTSF+RLD P G FRWLTVDLPP+
Sbjct 63 DMSLRALAFDKQTRRYLRDHPKATVVALAEGLQTSFYRLDAQGPDVGHDFRWLTVDLPPM 122
Query 121 VDLRTRLLPSSPRVSVCAQSALDYSWMD-------------------------SVDPAG- 154
++LR +LLP+S RV + AQSALD+SWMD VD AG
Sbjct 123 IELRRKLLPASDRVQMLAQSALDFSWMDRVPTDDGDVNQAGDDGDVNQAGDDGDVDQAGA 182
Query 155 -GVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKV 213
GVFITAEGLLMYLQPE+++ LI +CA FPGG+M+FDLPP FA R G R SLRY+V
Sbjct 183 DGVFITAEGLLMYLQPEESMALITECAARFPGGRMMFDLPPSAFAPLVRRGFRASLRYRV 242
Query 214 PRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTL 273
P MPF++S A+AADLVN VPGV AV D+ RG +N L T R+P+ DP+RP TL
Sbjct 243 PPMPFTLSPAEAADLVNTVPGVRAVHDVPAEHARGRILNALLWTAQRVPLLDPVRPMFTL 302
Query 274 LEF 276
LEF
Sbjct 303 LEF 305
>gi|108802193|ref|YP_642390.1| O-methyltransferase-like protein [Mycobacterium sp. MCS]
gi|119871346|ref|YP_941298.1| O-methyltransferase domain-containing protein [Mycobacterium
sp. KMS]
gi|108772612|gb|ABG11334.1| O-methyltransferase-like protein [Mycobacterium sp. MCS]
gi|119697435|gb|ABL94508.1| O-methyltransferase domain protein [Mycobacterium sp. KMS]
Length=266
Score = 307 bits (787), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 161/264 (61%), Positives = 186/264 (71%), Gaps = 0/264 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L+GVSETALLTLN RA +AR AIIDDPMA+ LV+SIDFDF KFG GQ ALR+ AFD
Sbjct 2 LSGVSETALLTLNGRAHQARHPKAIIDDPMAIRLVDSIDFDFDKFGRKGQEMALRSLAFD 61
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
AA YLD HP+ATVVALAEGLQTSFWRL A P F W+TVD PI+ LR RLLP S
Sbjct 62 RAAIQYLDAHPSATVVALAEGLQTSFWRLTSARPDLDFHWVTVDFEPIIALRERLLPHSD 121
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R+S AQSALD+SWMD VD + GVFITAEGLLMYLQP +++ LI +CA+ FPGGQM+FDL
Sbjct 122 RISTLAQSALDFSWMDHVDTSNGVFITAEGLLMYLQPHESMRLITECARRFPGGQMIFDL 181
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
PP + G+R S RY+VP MPFS++ Q ADL VPGV AV DL +P GRGL
Sbjct 182 PPVLVKKLAPNGMRASRRYRVPPMPFSLTPNQLADLAITVPGVRAVHDLPMPRGRGLLFE 241
Query 253 MALSTVYRLPVFDPLRPCLTLLEF 276
+ +R TLLEF
Sbjct 242 KLYPAFWEFKPTKQMRGAYTLLEF 265
>gi|183982739|ref|YP_001851030.1| O-methyltransferase Omt [Mycobacterium marinum M]
gi|183176065|gb|ACC41175.1| O-methyltransferase Omt [Mycobacterium marinum M]
Length=277
Score = 307 bits (787), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 157/264 (60%), Positives = 187/264 (71%), Gaps = 0/264 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L GVSETALLTLN RA +A + + IIDDPMA+ LVESIDFDF KFG GQ ALR+ A D
Sbjct 13 LGGVSETALLTLNGRAHQAAKPNPIIDDPMAIKLVESIDFDFEKFGRRGQEMALRSLAVD 72
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
YL +HP ATVVALAEG QT FWR+ A+P QFRW+++DL P+++LR RLLP S
Sbjct 73 RCEIAYLTKHPGATVVALAEGFQTGFWRVSNALPDTQFRWVSLDLEPVMELRRRLLPDSA 132
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
RV+ AQSALDY+WMD VD GVFITAEGLLMYLQP QA+ LI+QCA+ F GGQM FDL
Sbjct 133 RVTNLAQSALDYTWMDKVDSRAGVFITAEGLLMYLQPNQAMELISQCAKRFAGGQMFFDL 192
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
PP + G+R S RY+VP MPFS+SV Q A LV+ VPG+ AV D+ +P GRGL+
Sbjct 193 PPTIVKRVAPKGMRASRRYRVPPMPFSLSVNQLARLVDSVPGIRAVHDVPMPEGRGLFFK 252
Query 253 MALSTVYRLPVFDPLRPCLTLLEF 276
++R P P R LLEF
Sbjct 253 TLYPALWRFPPIKPFRGAYVLLEF 276
>gi|126438175|ref|YP_001073866.1| O-methyltransferase domain-containing protein [Mycobacterium
sp. JLS]
gi|126237975|gb|ABO01376.1| O-methyltransferase domain protein [Mycobacterium sp. JLS]
Length=266
Score = 306 bits (784), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 161/264 (61%), Positives = 186/264 (71%), Gaps = 0/264 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L+GVSETALLTLN RA +AR AIIDDPMA+ LV+SIDFDF KFG GQ ALR+ AFD
Sbjct 2 LSGVSETALLTLNGRAHQARHPKAIIDDPMAIRLVDSIDFDFDKFGRKGQEMALRSLAFD 61
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
AA +LD HP+ATVVALAEGLQTSFWRL A P F WLTVD PI+ LR RLLP S
Sbjct 62 RAAIRHLDAHPSATVVALAEGLQTSFWRLTSARPDLDFSWLTVDFEPIIALRERLLPHSD 121
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R+S AQSALD+SWMD VD + GVFITAEGLLMYLQP +++ LI +CA+ FPGGQM+FDL
Sbjct 122 RISTLAQSALDFSWMDHVDTSNGVFITAEGLLMYLQPHESMRLITECARRFPGGQMIFDL 181
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
PP + G+R S RY+VP MPFS++ Q ADL VPGV AV DL +P GRGL
Sbjct 182 PPVLVKKLAPNGMRASRRYRVPPMPFSLTPNQLADLAITVPGVRAVHDLPMPRGRGLLFE 241
Query 253 MALSTVYRLPVFDPLRPCLTLLEF 276
+ +R TLLEF
Sbjct 242 KLYPAFWEFKPTKQMRGAYTLLEF 265
>gi|296164975|ref|ZP_06847530.1| O-methyltransferase Omt [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295899623|gb|EFG79074.1| O-methyltransferase Omt [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=283
Score = 306 bits (783), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 171/269 (64%), Positives = 196/269 (73%), Gaps = 0/269 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
LTGVSETALLTL RA +A R D IIDDPMAV+LV+++DFDF KFG GQ ALR+ A D
Sbjct 14 LTGVSETALLTLYGRAYQAGRPDPIIDDPMAVSLVQALDFDFEKFGRRGQEMALRSLAVD 73
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
A YL HP ATVVALAEGLQTSFWRL A+P QFRWL+VDLPP+VDLR RLLP SP
Sbjct 74 RCAIDYLAAHPRATVVALAEGLQTSFWRLGRALPDAQFRWLSVDLPPVVDLRRRLLPRSP 133
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R++ AQSALDYSW+D VD GVF+TAEGLLMYLQP QALGLIAQCA+ FPGGQM FDL
Sbjct 134 RITDLAQSALDYSWIDQVDAGDGVFVTAEGLLMYLQPAQALGLIAQCAKRFPGGQMFFDL 193
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
PP +R GLR+S RY+VP MPFS+SV Q A L + VPG+ AV D+ +P GRGL+
Sbjct 194 PPTIVKKVARRGLRSSKRYRVPPMPFSLSVRQLAKLADTVPGIRAVHDVPMPAGRGLFFG 253
Query 253 MALSTVYRLPVFDPLRPCLTLLEFSRPAR 281
+R P P R LLEF +R
Sbjct 254 TLYPAFWRFPPVKPYRGVFALLEFGSVSR 282
>gi|118467412|ref|YP_890869.1| O-methyltransferase [Mycobacterium smegmatis str. MC2 155]
gi|118168699|gb|ABK69595.1| O-methyltransferase, putative [Mycobacterium smegmatis str. MC2
155]
Length=280
Score = 303 bits (776), Expect = 2e-80, Method: Compositional matrix adjust.
Identities = 154/265 (59%), Positives = 186/265 (71%), Gaps = 0/265 (0%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAF 71
ALT VSETALLTL RA + R + AI++DPMA+ LV+SI+FDF KFG GQ ALR+ AF
Sbjct 15 ALTRVSETALLTLYGRAYQGRHQQAILNDPMAIRLVDSIEFDFEKFGRKGQEMALRSLAF 74
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D AA YL P ATVVALAEGLQT+FWRL A+P +F WLTVD PI+DLR RLLP+
Sbjct 75 DRAALAYLSAQPRATVVALAEGLQTTFWRLTDALPDAEFHWLTVDFQPIIDLRRRLLPAD 134
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
PR++ AQSALDYSWMD VD GVFITAEGLLMYL+PE+++GLI QCA F GGQM+FD
Sbjct 135 PRITCLAQSALDYSWMDQVDTGDGVFITAEGLLMYLEPEESMGLIKQCANRFAGGQMVFD 194
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
LPP +++ GLR+S RY+VP MPFS++ Q DL VPG+ AV DL +P GRG
Sbjct 195 LPPVVVKKFAKKGLRSSKRYRVPPMPFSLTPNQLQDLARTVPGIRAVHDLPMPAGRGFLF 254
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
++ +R TLLE
Sbjct 255 EKVFPAFWQFKPTKQIRGAYTLLEL 279
>gi|118618411|ref|YP_906743.1| O-methyltransferase Omt [Mycobacterium ulcerans Agy99]
gi|118570521|gb|ABL05272.1| O-methyltransferase Omt [Mycobacterium ulcerans Agy99]
Length=277
Score = 297 bits (761), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 153/265 (58%), Positives = 183/265 (70%), Gaps = 0/265 (0%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L GVSETALLTLN RA +A + + IIDDPMA+ LVES DFDF KFG GQ ALR+ A D
Sbjct 13 LGGVSETALLTLNGRAHQAAKPNPIIDDPMAIKLVESNDFDFEKFGRRGQEMALRSLAVD 72
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
YL +HP ATVVA AEG QT FWR+ A+P QFRW+++DL P+++LR RLLP S
Sbjct 73 RCEIAYLTKHPGATVVAHAEGFQTGFWRVSNALPDTQFRWVSLDLEPVMELRRRLLPDSA 132
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
RV+ AQSALDY+WMD VD VFITAEGLLMY QP QA+ LI+QCA+ F GGQM FDL
Sbjct 133 RVTNLAQSALDYTWMDKVDSCAAVFITAEGLLMYPQPNQAMELISQCAKRFAGGQMFFDL 192
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
PP + G+R S RY+VP MPFS+SV Q A LV+ VPG+ AV D+ +P GRGL+
Sbjct 193 PPTIVKRVAPKGMRASRRYRVPPMPFSLSVNQLARLVDTVPGIRAVHDVPMPEGRGLFFR 252
Query 253 MALSTVYRLPVFDPLRPCLTLLEFS 277
++R P P R LLEF
Sbjct 253 TLYPALWRFPPIKPFRGAYVLLEFD 277
>gi|169627771|ref|YP_001701420.1| O-methyltransferase OmT [Mycobacterium abscessus ATCC 19977]
gi|169239738|emb|CAM60766.1| Probable O-methyltransferase OmT [Mycobacterium abscessus]
Length=268
Score = 280 bits (715), Expect = 3e-73, Method: Compositional matrix adjust.
Identities = 148/264 (57%), Positives = 183/264 (70%), Gaps = 5/264 (1%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L GVSETALLTL+ RA EA R D I+DDPMA++L S+D+DFA FG T Q ALRA FD
Sbjct 9 LDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQATALRALIFD 68
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
A + YLD HP ATVVALAEGLQTSFWR+D G+ WL+VDL PIV LR RLLP S
Sbjct 69 KATREYLDYHPCATVVALAEGLQTSFWRVD----NGRLTWLSVDLEPIVRLRQRLLPRSE 124
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R+S CAQSALDYSWMD VD + GV ITAEGL YL+ + LI+ CAQ FPGG+++FD
Sbjct 125 RLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLERDLVFDLISVCAQRFPGGRLIFDS 184
Query 193 PPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWVN 252
P++ + S+ G+R S +Y VP MPFS + Q D + +PG+ +VR+LR+P GRG +
Sbjct 185 VPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQ-YDELRAIPGIRSVRELRMPAGRGKVLR 243
Query 253 MALSTVYRLPVFDPLRPCLTLLEF 276
A +Y LP D R T++EF
Sbjct 244 WAAPLLYALPGLDRWRAPHTVVEF 267
>gi|169628385|ref|YP_001702034.1| O-methyltransferase OMT [Mycobacterium abscessus ATCC 19977]
gi|169240352|emb|CAM61380.1| Probable O-methyltransferase OMT [Mycobacterium abscessus]
Length=272
Score = 274 bits (700), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 144/265 (55%), Positives = 180/265 (68%), Gaps = 6/265 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L GVSETAL+TLN RA EA R D +++DPMA+ L +S+D+D+ FG T QG ALRA FD
Sbjct 12 LDGVSETALITLNQRATEANRPDGVLEDPMAIVLRDSLDYDYHHFGRTHQGIALRALTFD 71
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
+ YL +HP ATVVALAEGLQTSFWR+D G+ WL+VDL PIV LR +LLP S
Sbjct 72 TVSNEYLAEHPRATVVALAEGLQTSFWRID----NGELNWLSVDLEPIVRLRRQLLPPSD 127
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
RV AQSALD+SWMD VD + GV ITAEGL MYL+ + LIA CA+ FPGG M+FD
Sbjct 128 RVRYVAQSALDHSWMDQVDDSNGVLITAEGLFMYLERDVVFDLIAACAKRFPGGWMVFDT 187
Query 193 PPRWFAGWS-RLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
P + +S R G R S Y VP MPFS + Q L + GV AVR++R+P GRG ++
Sbjct 188 IPWLMSVYSRRRGWRLSEHYTVPPMPFSFTAHQYGQL-RALDGVSAVREVRMPAGRGTFL 246
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
+A Y LP+ D +RP +T++EF
Sbjct 247 KLATPLFYNLPLSDRIRPAMTVVEF 271
>gi|169628388|ref|YP_001702037.1| O-methyltransferase OMT [Mycobacterium abscessus ATCC 19977]
gi|169240355|emb|CAM61383.1| Probable O-methyltransferase OMT [Mycobacterium abscessus]
Length=282
Score = 260 bits (665), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 135/265 (51%), Positives = 178/265 (68%), Gaps = 2/265 (0%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAF 71
+L GVS T L TL+ R EA+R D++I DP+A L ++I++D+ KFG Q ALRA AF
Sbjct 19 SLEGVSATTLWTLHNRGTEAKRPDSVIRDPLAAELFDAIEYDYRKFGRPSQTHALRALAF 78
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A+ YL HP A +VALAEG+QTSFWRL A QF W +VDLPP+++LR +LLP+
Sbjct 79 DTQARVYLATHPRAAIVALAEGMQTSFWRLGGADATAQFTWYSVDLPPVMELRNQLLPND 138
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R+ AQSALD SWMD VD +GG FITAEGLLMYLQPE++LGLI CA+ FPGGQM+FD
Sbjct 139 ERIVKLAQSALDLSWMDQVDASGGAFITAEGLLMYLQPEESLGLIEACAKRFPGGQMMFD 198
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
P WF+ + G + S RY P MPF+++ + L++ +PGVV D+ + GRG+W
Sbjct 199 SIPHWFSRRTLQGFKLSDRYVAPPMPFALTPDEGEALIS-IPGVVTAIDIPLHRGRGIWK 257
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
+ + R RP +TLL+F
Sbjct 258 FVNSKRLDR-GFLRRTRPSMTLLQF 281
>gi|317506383|ref|ZP_07964193.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
gi|316255322|gb|EFV14582.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
Length=268
Score = 259 bits (661), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 145/271 (54%), Positives = 177/271 (66%), Gaps = 5/271 (1%)
Query 6 PAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFA 65
PA L GVSETAL+TL RAAEA R D +I+DPMAVAL E ID+D+ FG Q A
Sbjct 2 PAIDARHLDGVSETALITLYHRAAEAARADGVIEDPMAVALRERIDYDYDHFGSPRQVTA 61
Query 66 LRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRT 125
LRA FD AA+ YL P ATVVALAEGLQTSFWR+D G+ WL+VDL P++ LR
Sbjct 62 LRAVIFDRAAREYLAARPRATVVALAEGLQTSFWRVD----NGELSWLSVDLEPVIQLRQ 117
Query 126 RLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPG 185
+ LP+S R+ CAQSALDYSWMD VD A GV ITAEGL YL+ + LIA CAQ FPG
Sbjct 118 QALPASDRLRHCAQSALDYSWMDQVDDADGVLITAEGLFQYLERDLVFDLIAACAQRFPG 177
Query 186 GQMLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPP 245
G ++FD P++ + +S+ G+R S Y +P MPF + A D + + GV AVR+L VP
Sbjct 178 GWLVFDSVPKFLSSFSQRGMRLSKHYTMPPMPFPFT-ADRYDELRALDGVRAVRELPVPR 236
Query 246 GRGLWVNMALSTVYRLPVFDPLRPCLTLLEF 276
GRG + L YRLP D R T++EF
Sbjct 237 GRGAVLRWGLPLFYRLPRLDRFRAPHTVVEF 267
>gi|183980294|ref|YP_001848585.1| O-methyltransferase Omt_1 [Mycobacterium marinum M]
gi|183173620|gb|ACC38730.1| O-methyltransferase Omt_1 [Mycobacterium marinum M]
Length=269
Score = 257 bits (657), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 144/265 (55%), Positives = 173/265 (66%), Gaps = 6/265 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L G+SETALLTL+ RA EA R DAIIDDPMA+AL ID+ + FG T Q ALRA AFD
Sbjct 9 LDGISETALLTLHQRATEAARPDAIIDDPMAIALRNDIDYPYHHFGRTHQATALRALAFD 68
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
+ + +L HP ATVVALAEGLQTSFWRLD G+ WL+VDL PIV LR +LLP+
Sbjct 69 NSTRDFLRTHPGATVVALAEGLQTSFWRLD----NGELNWLSVDLAPIVRLREQLLPACD 124
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R+ CAQSA DYSWM+ VD GV ITAEGL YL+ + LIA CA+ FP GQ++FD
Sbjct 125 RLRYCAQSAFDYSWMEQVDDTNGVLITAEGLFQYLRRDVVFELIAACAKRFPHGQLVFDS 184
Query 193 PPRWFAGWS-RLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
P + +S R G R S Y P MPF + A D + +PGV AVR+L P GRG ++
Sbjct 185 IPWLLSVYSRRRGFRLSEHYTAPPMPFWFT-ADHYDELRAIPGVRAVRELPAPAGRGRFL 243
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
AL YRLP LR +TL+EF
Sbjct 244 RWALPVAYRLPGLGRLRAPVTLVEF 268
>gi|312199062|ref|YP_004019123.1| Leucine carboxyl methyltransferase [Frankia sp. EuI1c]
gi|311230398|gb|ADP83253.1| Leucine carboxyl methyltransferase [Frankia sp. EuI1c]
Length=280
Score = 249 bits (636), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 134/267 (51%), Positives = 169/267 (64%), Gaps = 4/267 (1%)
Query 11 VALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARA 70
AL GV+ T L TL RA E+ + DDP+A L ID+DF +FG Q LRA A
Sbjct 13 AALDGVAATCLWTLRNRAEESMHPGSAFDDPLAERLYRGIDYDFERFGKPSQSHPLRALA 72
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
D A + YL++HPAATVVAL EGLQT++WRL PG WL+VDLPP++DLR RLLP
Sbjct 73 LDSAIRGYLERHPAATVVALGEGLQTTYWRL--GRPG--LDWLSVDLPPVIDLRRRLLPQ 128
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
P ++ SALD +WMD DP GVFI+AEGL MYL+ + + LIA+CA FPGG++ F
Sbjct 129 EPGLTAMPTSALDRAWMDVPDPGRGVFISAEGLFMYLERDSVMSLIAECAARFPGGRLFF 188
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
D P F+ + G R S RY P MPFS+SV++AA L ++PGV DL+ PPGR W
Sbjct 189 DSIPAAFSSRTMKGYRMSDRYTAPPMPFSLSVSEAARLPTQIPGVATAEDLQPPPGRKAW 248
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEFS 277
+ L V LP LRP +TLL F+
Sbjct 249 RSRTLRKVANLPGPRDLRPSITLLSFA 275
>gi|118619892|ref|YP_908224.1| O-methyltransferase Omt_1 [Mycobacterium ulcerans Agy99]
gi|118572002|gb|ABL06753.1| O-methyltransferase Omt_1 [Mycobacterium ulcerans Agy99]
Length=269
Score = 248 bits (633), Expect = 8e-64, Method: Compositional matrix adjust.
Identities = 140/265 (53%), Positives = 170/265 (65%), Gaps = 6/265 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L +SETALLTL+ RA EA R DAIIDDPMA+AL ID+ + FG T Q ALRA AFD
Sbjct 9 LDDISETALLTLHQRATEAARPDAIIDDPMAIALRNDIDYPYHHFGRTHQATALRALAFD 68
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
+ + +L P ATVVALAEGLQTSFWRLD G+ WL+VDL PIV LR +LLP+
Sbjct 69 NSTRDFLQTRPGATVVALAEGLQTSFWRLD----NGELNWLSVDLAPIVRLREQLLPACD 124
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDL 192
R+ CAQSA DYSWM+ VD GV ITAEGL YL+ + LIA CA+ P GQ++FD
Sbjct 125 RLRYCAQSAFDYSWMEQVDDTNGVLITAEGLFQYLRRDVVFELIAACAKRVPHGQLVFDS 184
Query 193 PPRWFAGWS-RLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLWV 251
P + +S R G + S Y P MPF + A D + +PGV AVR+L P GRG ++
Sbjct 185 IPWLLSVYSRRRGFKLSEHYTAPPMPFWFT-ADHYDELRAIPGVRAVRELPAPAGRGRFL 243
Query 252 NMALSTVYRLPVFDPLRPCLTLLEF 276
AL YRLP LR +TL+EF
Sbjct 244 RWALPVAYRLPGLGRLRAPVTLVEF 268
>gi|226362741|ref|YP_002780519.1| methyltransferase [Rhodococcus opacus B4]
gi|226241226|dbj|BAH51574.1| putative methyltransferase [Rhodococcus opacus B4]
Length=275
Score = 238 bits (606), Expect = 9e-61, Method: Compositional matrix adjust.
Identities = 127/267 (48%), Positives = 166/267 (63%), Gaps = 4/267 (1%)
Query 11 VALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARA 70
LTGV T + TL RA EA R DP+AV L E++D+ + FG Q LRA A
Sbjct 12 TTLTGVPATMMWTLRNRAVEAARPGTAFADPLAVQLYETLDYPYENFGKPSQSHPLRALA 71
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD + +L HP TVVAL EGLQTS+WR + PG RW+++DLP ++ LR +LLP
Sbjct 72 FDDEIRAFLAAHPGGTVVALGEGLQTSYWR--IGDPG--VRWVSIDLPEVIALRRQLLPD 127
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
P V+ A SALD SWMD VDP GVF++AEGLLMYL P+++L LI CA+ FPGG+M+F
Sbjct 128 EPNVTTLAVSALDRSWMDHVDPGRGVFVSAEGLLMYLPPDESLTLIGDCARRFPGGRMMF 187
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
D P+WF+ ++ GLR Y VP MPF +S +AADL +VP + R++ +P GRGLW
Sbjct 188 DSVPKWFSRKTQKGLRIHGGYTVPPMPFHLSAGEAADLPGQVPDLAFTREVMLPLGRGLW 247
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEFS 277
+ L + RP LTL F+
Sbjct 248 GSTLLRRLSESRPLRNSRPTLTLCGFA 274
>gi|300786085|ref|YP_003766376.1| O-methyltransferase OMT [Amycolatopsis mediterranei U32]
gi|299795599|gb|ADJ45974.1| O-methyltransferase OMT [Amycolatopsis mediterranei U32]
Length=299
Score = 233 bits (593), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 132/287 (46%), Positives = 166/287 (58%), Gaps = 23/287 (8%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAF 71
AL GV+ T L TL RA E+R + DP+A L I D+ +FG Q LRA A
Sbjct 16 ALGGVAATCLWTLRNRAEESRHPGSAFADPLAERLHRRISHDYERFGKPNQIHPLRAVAL 75
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A + YLD++PAATVVAL EGLQT++WRL W++VDLPP++ LR RLLP
Sbjct 76 DFAIRAYLDRYPAATVVALGEGLQTTYWRLGRP----AVDWVSVDLPPVIGLRLRLLPPE 131
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
PR++ A SALD W+D DPA GVFI+AEGL MYL ++ LIA CA FPGGQ+ FD
Sbjct 132 PRMTAIAASALDRGWLDVPDPARGVFISAEGLFMYLDRDEVFALIADCAARFPGGQLFFD 191
Query 192 LPPRWF-------------------AGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKV 232
P W AG GLR S RY VP MPF ++V+ AA L ++
Sbjct 192 SIPPWLSRRTLKGGARGRPPFSTLPAGTDNSGLRLSARYAVPPMPFGLTVSGAARLPGRI 251
Query 233 PGVVAVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRP 279
PGV AV D++ PPGR W L + LP LRP ++L+ F+ P
Sbjct 252 PGVAAVEDVQPPPGRKAWRPGTLRKLANLPGLRDLRPSISLVSFAGP 298
>gi|340527552|gb|AEK42757.1| O-methyltransferase OMT [Amycolatopsis mediterranei S699]
Length=294
Score = 232 bits (592), Expect = 4e-59, Method: Compositional matrix adjust.
Identities = 132/287 (46%), Positives = 166/287 (58%), Gaps = 23/287 (8%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAF 71
AL GV+ T L TL RA E+R + DP+A L I D+ +FG Q LRA A
Sbjct 11 ALGGVAATCLWTLRNRAEESRHPGSAFADPLAERLHRRISHDYERFGKPNQIHPLRAVAL 70
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A + YLD++PAATVVAL EGLQT++WRL W++VDLPP++ LR RLLP
Sbjct 71 DFAIRAYLDRYPAATVVALGEGLQTTYWRLGRP----AVDWVSVDLPPVIGLRLRLLPPE 126
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
PR++ A SALD W+D DPA GVFI+AEGL MYL ++ LIA CA FPGGQ+ FD
Sbjct 127 PRMTAIAASALDRGWLDVPDPARGVFISAEGLFMYLDRDEVFALIADCAARFPGGQLFFD 186
Query 192 LPPRWF-------------------AGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKV 232
P W AG GLR S RY VP MPF ++V+ AA L ++
Sbjct 187 SIPPWLSRRTLKGGARGRPPFSTLPAGTDNSGLRLSARYAVPPMPFGLTVSGAARLPGRI 246
Query 233 PGVVAVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRP 279
PGV AV D++ PPGR W L + LP LRP ++L+ F+ P
Sbjct 247 PGVAAVEDVQPPPGRKAWRPGTLRKLANLPGLRDLRPSISLVSFAGP 293
>gi|297159773|gb|ADI09485.1| O-methyltransferase OMT [Streptomyces bingchenggensis BCW-1]
Length=286
Score = 218 bits (554), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 127/279 (46%), Positives = 162/279 (59%), Gaps = 18/279 (6%)
Query 8 KQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGP----TGQ 62
K V L+ V ET L L RA EAR+ ++ DP A+ LV+ +DF F + FGP Q
Sbjct 6 KVTVRLSPVPETLLWNLYHRAYEARQPRTVLHDPKAIELVDRLDFPFEETFGPPHPLLAQ 65
Query 63 GFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVD 122
G ALR R+FD A Q +L HP TVV LAEGL+T FWR+D G+ RWL V+LP +
Sbjct 66 GQALRVRSFDAAVQSFLADHPTGTVVNLAEGLETQFWRID----NGRARWLGVELPETAE 121
Query 123 LRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQT 182
LR LLP + R AQS LD SWMD VD GGV +TA+GLLMYL+P Q LIA CA+
Sbjct 122 LRLALLPDTERRRTLAQSVLDLSWMDEVDTEGGVLLTAQGLLMYLRPPQVRELIAACAER 181
Query 183 FPGGQMLFDLPPRWF-AGWSRLGLRTSLR--------YKVPRMPFSMSVAQAADLVNKVP 233
F GG ++FD PRW AG R R R Y++P MP+ ++ + + P
Sbjct 182 FRGGALVFDAVPRWLSAGTQRDERRGEKRGEKRPAPGYRMPGMPWGLNAGELEKVRTAHP 241
Query 234 GVVAVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLT 272
GVV VR+L +P GRG + ++RLP LRP +T
Sbjct 242 GVVDVRELHLPRGRGPYFGALTPVLHRLPALRNLRPTMT 280
>gi|345008735|ref|YP_004811089.1| methyltransferase [Streptomyces violaceusniger Tu 4113]
gi|344035084|gb|AEM80809.1| methyltransferase [Streptomyces violaceusniger Tu 4113]
Length=295
Score = 209 bits (532), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 127/279 (46%), Positives = 167/279 (60%), Gaps = 10/279 (3%)
Query 2 SAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FG-P 59
S + +RV L+ V ET L L+ RAAEARR ++DDP AV LV+ ID+ F + FG P
Sbjct 17 SGNGEGGRRVELSEVPETLLWNLHMRAAEARRARTVLDDPKAVELVDRIDYPFEETFGAP 76
Query 60 T---GQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVD 116
T QG ALR R FDMA + +LD+HP TVV LAEGL+T FWR+D G+ RWL V+
Sbjct 77 TPLLAQGHALRVRTFDMAVRAFLDEHPDGTVVTLAEGLETQFWRVD----NGRARWLCVE 132
Query 117 LPPIVDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLI 176
LP ++R LLP R A+SALD SW D VDPA GV ITA+GLLMYL+P + LI
Sbjct 133 LPETAEVRRALLPDEERRRTLARSALDLSWRDEVDPARGVLITAQGLLMYLRPTEVKDLI 192
Query 177 AQCAQTFPGGQMLFDLPPRWFAGWSRLG-LRTSLRYKVPRMPFSMSVAQAADLVNKVPGV 235
A CA+ F G ++FD PRWF+ + G +RT+ Y+ P MP+ M + + P +
Sbjct 193 AGCAERFRGAALVFDAVPRWFSARTTRGEMRTAQGYRTPPMPWGMDAGELPKVRTAHPAI 252
Query 236 VAVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLL 274
VR++ P GRG + + LP LRP +T +
Sbjct 253 TDVREVPPPRGRGFYYGAVAPLMRWLPAVRNLRPTMTAI 291
>gi|302543145|ref|ZP_07295487.1| putative O-methyltransferase [Streptomyces hygroscopicus ATCC
53653]
gi|302460763|gb|EFL23856.1| putative O-methyltransferase [Streptomyces himastatinicus ATCC
53653]
Length=281
Score = 208 bits (529), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 122/272 (45%), Positives = 160/272 (59%), Gaps = 10/272 (3%)
Query 9 QRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGP----TGQG 63
+RV L+GV ET L L RA EAR ++ DP AV LV+ ID+ F + FGP QG
Sbjct 10 RRVELSGVPETLLWNLYMRAYEARGPRPVLTDPKAVELVDRIDYPFEETFGPPSPLLAQG 69
Query 64 FALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDL 123
ALR R FD A + +L HP TVV LAEGL+T +WR+D G+ RWL V+LP +
Sbjct 70 HALRVRTFDDAVRDFLTAHPDGTVVTLAEGLETQYWRVD----NGRARWLCVELPETAAV 125
Query 124 RTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTF 183
R LLP R A+SALD SW VD + GV ITA+GLLMYL+P + LIA CA+ F
Sbjct 126 RRALLPDDERRRTLARSALDLSWRGEVDASRGVLITAQGLLMYLRPTEVRDLIAGCAEGF 185
Query 184 PGGQMLFDLPPRWFAGWSRLG-LRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR 242
PGG ++FD PRWF+ + G LRT+ Y+ P MP+ M + + + P + VR+L
Sbjct 186 PGGALVFDAVPRWFSARTMRGELRTARGYRPPPMPWGMDAGELGKVRSAHPRISEVRELP 245
Query 243 VPPGRGLWVNMALSTVYRLPVFDPLRPCLTLL 274
P GRG + + + RLP LRP +T +
Sbjct 246 PPRGRGPYHGALVPVLRRLPGVRNLRPTMTAI 277
>gi|296392751|ref|YP_003657635.1| O-methyltransferase domain-containing protein [Segniliparus rotundus
DSM 44985]
gi|296179898|gb|ADG96804.1| O-methyltransferase domain protein [Segniliparus rotundus DSM
44985]
Length=281
Score = 204 bits (519), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 118/248 (48%), Positives = 150/248 (61%), Gaps = 15/248 (6%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFA-KFGPTGQGFALRARAF 71
LT VSETAL TL R +EA R + II D +AV L+E ID+ + +FG Q FALRA AF
Sbjct 9 LTDVSETALWTLWCRGSEAARPNPIIHDELAVRLLEHIDYPYEQRFGAPTQTFALRASAF 68
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A + +L +HP TVV+LAEG QTS+WRL + RW++VDLPP+V LR +LLP
Sbjct 69 DAAVRDFLGEHPNGTVVSLAEGFQTSYWRLGRP----RTRWVSVDLPPVVRLREQLLPQE 124
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
+ A SALD++W D V+P V ITAEGLL YL+ ALGLI CAQ FP G+ LFD
Sbjct 125 EHIVPVATSALDFAWADHVEPGSPVLITAEGLLCYLEKPLALGLIRGCAQRFPAGRFLFD 184
Query 192 LPPRWFA--GWSRLGLRTSL--------RYKVPRMPFSMSVAQAADLVNKVPGVVAVRDL 241
P W+ + G + L +Y VP MPF S + + +PGV AVR +
Sbjct 185 ALPSWWTKKKYKTFGTKDQLIGGSLAKTKYVVPPMPFPASPIEISKYPETIPGVAAVRPV 244
Query 242 RVPPGRGL 249
+ GRGL
Sbjct 245 PIGAGRGL 252
>gi|336118766|ref|YP_004573538.1| putative methyltransferase [Microlunatus phosphovorus NM-1]
gi|334686550|dbj|BAK36135.1| putative methyltransferase [Microlunatus phosphovorus NM-1]
Length=272
Score = 201 bits (510), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 120/275 (44%), Positives = 162/275 (59%), Gaps = 15/275 (5%)
Query 11 VALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESID---FDFAKFGPTGQGFALR 67
V L+GV ET L TL RA EA R + + DP AV L ++ DF +FG Q LR
Sbjct 4 VDLSGVPETTLWTLRNRAEEAMRPGSYLVDPEAVRLYRTLQDSGEDFQRFGKLSQSHPLR 63
Query 68 ARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRL---DVAIPGGQFRWLTVDLPPIVDLR 124
A AFD +L HP VVAL EGLQT++WRL DVA W +VDLP +VD +
Sbjct 64 ALAFDTVIADFLAGHPRGPVVALGEGLQTTYWRLGRPDVA-------WYSVDLPEVVDAQ 116
Query 125 TRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFP 184
RLLP ++ +SALD +W++ V AG ITAEGL MYL ++ LIA A FP
Sbjct 117 RRLLPEEQAITRIGRSALDDTWLEEV-AAGPALITAEGLFMYLPKDEVHALIADLAARFP 175
Query 185 GGQMLFDLPPRWFAGWSRLG-LRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRV 243
GG++++D P WF+ + G ++ S RY P MP + +V++AA L + +PGV +VRD+ +
Sbjct 176 GGRLVYDAIPAWFSTMTVKGKVKLSDRYVAPPMPHAQTVSEAARLTDVIPGVASVRDVLL 235
Query 244 PPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSR 278
PPGRG+W N A+ + P RP +TLL F+
Sbjct 236 PPGRGVWANPAMRRLAGAPWVRDHRPSITLLTFAE 270
>gi|317509366|ref|ZP_07966986.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
gi|316252422|gb|EFV11872.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
Length=280
Score = 196 bits (498), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 124/276 (45%), Positives = 160/276 (58%), Gaps = 16/276 (5%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
LT VSETALLTL +R +EA R D+II+DP+A L++ I++ + + FGP Q FA+RA F
Sbjct 9 LTDVSETALLTLWSRGSEAARADSIINDPLAARLLDRIEYPYRRHFGPPNQFFAIRAATF 68
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A+ +L +HP T++ALAEGLQTS+WRL P W++VDLPPIV LR +LLP
Sbjct 69 DRVARGFLREHPNGTIIALAEGLQTSYWRL--GRPPAP--WISVDLPPIVALREQLLPKE 124
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
V SALD SW D V V ITAEGLL YL ALGLI CA FPGG+ +FD
Sbjct 125 EHVVHAGTSALDLSWADHVQTGAPVLITAEGLLYYLDKPLALGLIRDCAARFPGGRFVFD 184
Query 192 -LPPRWFAGWSRLGLRTSLR--------YKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR 242
LP + L + LR + +P MPFSM V + +PGV + R +
Sbjct 185 SLPTLGTSKTGTLLAKAQLRANKLLKRDFVMPTMPFSMHVKEIRTYPRTIPGVASARQVP 244
Query 243 VPPGRGLWVNMALSTVYRLPVF-DPLRPCLTLLEFS 277
V GRG+ + Y+ P+ LR +T L FS
Sbjct 245 VTVGRGIQ-GWGVQKFYQSPLIPSRLRGTITELRFS 279
>gi|164690687|dbj|BAF98637.1| putative methyl transferase [Streptomyces argenteolus]
Length=318
Score = 181 bits (459), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 111/248 (45%), Positives = 147/248 (60%), Gaps = 11/248 (4%)
Query 8 KQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FG-PTG---Q 62
K ++ L V ET L TL RA EAR + ++ DP AV LVE+I++ F K FG PT Q
Sbjct 24 KLKLDLGDVQETMLWTLYHRATEARDPETVLHDPWAVQLVETIEYPFEKRFGTPTAGQAQ 83
Query 63 GFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVD 122
ALRAR FD + +L +HP TVVAL EGL+T F R+D G+ WL+VDLP +++
Sbjct 84 WQALRARCFDEEIRRFLARHPDGTVVALGEGLETQFSRVD----NGRVHWLSVDLPEVIE 139
Query 123 LRTRLLPS-SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQ 181
+R RL P +PR A S LD WM +D + G+ +TA GLLMYL+P Q GLIA CA+
Sbjct 140 VRRRLRPDDAPRQRSLACSVLDDRWMTGLDGSRGLLVTARGLLMYLRPTQVHGLIAACAE 199
Query 182 TFPGGQMLFDLPPRWFAGWSRLG-LRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD 240
PGG +LFD P W + S L RT Y+ P + + + A L P +V +R+
Sbjct 200 RLPGGALLFDAVPSWLSRRSTLTPRRTPTGYRFPPWLWGVDAGETARLQALHPNIVDIRE 259
Query 241 LRVPPGRG 248
+R P GRG
Sbjct 260 IRPPRGRG 267
>gi|91779748|ref|YP_554956.1| putative O-methyltransferase [Burkholderia xenovorans LB400]
gi|91692408|gb|ABE35606.1| putative O-methyltransferase [Burkholderia xenovorans LB400]
Length=286
Score = 167 bits (423), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 100/267 (38%), Positives = 141/267 (53%), Gaps = 7/267 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFA-KFGPTGQGFALRARAF 71
L GVSET L TL RA E+ R D ++ D +V + E+ID+DFA +FG FA+RA
Sbjct 25 LDGVSETMLWTLYDRACESGRSDGVLTDHDSVRICEAIDYDFAGRFGSPDGSFAVRAAEI 84
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D +L+ HP VV+L EGL+T R+D G+ +WLTVDLP ++ R L S
Sbjct 85 DHLIMRWLESHPDGVVVSLGEGLETQAHRVD----NGRMQWLTVDLPAAIEFRENFLKPS 140
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R A +ALD +W + ++P VFI A+GL MYL+P L A A FP +++FD
Sbjct 141 KRFHHIAANALDLAWANEIEPTADVFIVAQGLFMYLEPTAVKRLFADLAARFPKAELVFD 200
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQ-AADLVNKVPGVVAVRDLRVPPGRGLW 250
+ P+WF+ + G+ + RY +P MP+ + A L GV VR L RG W
Sbjct 201 VIPQWFSSLTMWGVMKTPRYLLPPMPWGIDADNIGACLREWSSGVETVRLLEYRAPRG-W 259
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEFS 277
+ + P PCL + F+
Sbjct 260 PKVMEDLLCMNPANKRYLPCLVHVTFA 286
>gi|296161122|ref|ZP_06843932.1| O-methyltransferase domain protein [Burkholderia sp. Ch1-1]
gi|295888645|gb|EFG68453.1| O-methyltransferase domain protein [Burkholderia sp. Ch1-1]
Length=291
Score = 167 bits (423), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 98/267 (37%), Positives = 143/267 (54%), Gaps = 7/267 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFA-KFGPTGQGFALRARAF 71
L GVSET L TL RA E+ R D ++ DP +V + ++ID+DFA +FG FA+RA
Sbjct 30 LDGVSETMLWTLYDRACESARADGVLTDPESVRICKAIDYDFAGRFGTPDGSFAVRAAEI 89
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D +L+ HP +V+L EGL+T R+D G+ +WLTVDLP ++ R L S
Sbjct 90 DHLIMRWLEGHPDGVIVSLGEGLETQARRVD----NGRMQWLTVDLPAAIEFRENFLKPS 145
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R+ A +ALD +W D ++P VFI A+GL MYLQP L A A FP +++FD
Sbjct 146 KRLHHIAANALDLAWADEIEPTADVFIVAQGLFMYLQPTAVKRLFADLAARFPKAELVFD 205
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQ-AADLVNKVPGVVAVRDLRVPPGRGLW 250
+ P+WF+ + G+ + Y +P MP+ + A L G+ A++ L RG W
Sbjct 206 VIPQWFSSLTMWGVMKTPCYLLPPMPWGIDADHIGACLGEWSSGIEAIKLLEYRAPRG-W 264
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEFS 277
+ + P PCL + F+
Sbjct 265 PKVMEDLLCVNPANKRYLPCLVHVTFA 291
>gi|294676967|ref|YP_003577582.1| O-methyltransferase domain-containing protein [Rhodobacter capsulatus
SB 1003]
gi|294475787|gb|ADE85175.1| O-methyltransferase domain protein [Rhodobacter capsulatus SB
1003]
Length=278
Score = 166 bits (420), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 104/270 (39%), Positives = 145/270 (54%), Gaps = 13/270 (4%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAKFGPTGQGFALRARAFD 72
L GV ET L L +RA DDPMAV L+ ID+DF +FGP A+R++ D
Sbjct 17 LGGVPETLLWPLRSRAGMTVLDRGFFDDPMAVDLLNRIDYDFDRFGPVSHWHAVRSKYSD 76
Query 73 MAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSP 132
+ YL +HP A V+AL EGL+T FWRLD G+ RWL VDLP + LR +LLP P
Sbjct 77 GLIRRYLARHPEAQVLALGEGLETQFWRLD----NGRLRWLCVDLPESIALRRQLLPDHP 132
Query 133 RVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQC-AQTFPG-GQMLF 190
R++ SALD + ++VDP G F+TA GL+MY E+ L L+ + A P ++ F
Sbjct 133 RLTELPLSALDPAVFEAVDPERGFFVTAAGLVMYFTAEETLALLRRIGAHRGPSPAEIFF 192
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPG---VVAVRDLRVPPGR 247
D P WF+ + G+ Y P+MPF+++ + +VPG V A+ P R
Sbjct 193 DTIPHWFSRRTLRGMVVDKDYTAPQMPFALARRDVPAFLRQVPGLSLVTAIGYGEAFPER 252
Query 248 GLWVNMALSTVYRLPVFDPLRPCLTLLEFS 277
+ ++T+ RLPV + P L F
Sbjct 253 ----SRLIATLGRLPVVRDMAPLLLHARFG 278
>gi|108756995|ref|YP_633338.1| putative O-methyltransferase [Myxococcus xanthus DK 1622]
gi|108460875|gb|ABF86060.1| putative O-methyltransferase [Myxococcus xanthus DK 1622]
Length=274
Score = 165 bits (417), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 89/210 (43%), Positives = 126/210 (60%), Gaps = 5/210 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
LTG+ ET L TL++RA EA+R D ++ D A+ + +ID+DF K FG A+RA
Sbjct 9 LTGIPETMLWTLHSRAGEAKRPDGVLKDAEALRIYGAIDYDFEKSFGRAEPSLAIRAVEM 68
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D + + +L HP VV+L EGL+T RLD G+ RWL+VDLP V +R R L +
Sbjct 69 DRSIRAWLATHPDGFVVSLGEGLETQAQRLD----NGRLRWLSVDLPEAVAIRERFLTPN 124
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R+ SA+D +WMD VD + GVFI A+GL MY + + LI A+ FPG ++LFD
Sbjct 125 ERLMHFPVSAMDRAWMDRVDASKGVFIVAQGLFMYFEEDDVRRLIVDIAERFPGAELLFD 184
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMS 221
PRW + + GL + Y+VP MP+ ++
Sbjct 185 TIPRWLSRRTLKGLHRTRAYQVPPMPWGIN 214
>gi|343919061|gb|EGV29816.1| O-methyltransferase domain-containing protein [Thiorhodococcus
drewsii AZ1]
Length=270
Score = 159 bits (402), Expect = 5e-37, Method: Compositional matrix adjust.
Identities = 87/219 (40%), Positives = 125/219 (58%), Gaps = 5/219 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
LTGV ET L TL+ R +EA R D I D A + SID+D+A+ FG A R+ F
Sbjct 4 LTGVPETMLWTLHNRGSEAVRPDGFIRDQEAARIYASIDYDYARNFGRPDGSHATRSVMF 63
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D ++ +HP TVV L GL+T F R+D GQ RWL VD+P + +R R L S
Sbjct 64 DEVVGDWMKRHPGGTVVELGCGLETQFQRID----DGQVRWLCVDVPEAIAVRERFLAPS 119
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R +SALD SWMD+V+ +G VF+TA+GLLMY + + L+ FP +++FD
Sbjct 120 ERCRFVPKSALDLSWMDAVETSGPVFVTAQGLLMYFEEAEVKRLLTAILDRFPDVELMFD 179
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVN 230
+ P WF+ + GL+ + Y+ P MP+ + ++ L+
Sbjct 180 VIPPWFSRKTMSGLQKTRHYRAPEMPWGVGHSELEPLLR 218
>gi|296445744|ref|ZP_06887697.1| phosphoribosylamine/glycine ligase [Methylosinus trichosporium
OB3b]
gi|296256724|gb|EFH03798.1| phosphoribosylamine/glycine ligase [Methylosinus trichosporium
OB3b]
Length=694
Score = 155 bits (391), Expect = 8e-36, Method: Compositional matrix adjust.
Identities = 94/266 (36%), Positives = 133/266 (50%), Gaps = 6/266 (2%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDF-AKFGPTGQGFALRARA 70
AL GV ET L TL+ RA EA R D ++ D + + ++D+D+ FGP A RA
Sbjct 433 ALAGVPETMLWTLHNRAGEAMRSDGVLKDAKTLEIYRALDYDYEGAFGPATPSHAARAAF 492
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD + +L HP +V L EGL+T +R + G W+TVDLP + +R R +
Sbjct 493 FDEELRGFLATHPDGVIVNLGEGLETHRYR----VGGADALWITVDLPESIAIRERFIAP 548
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
A SALD W D+V P V+ITA+GLLMYL P++ LIA AQ FPG F
Sbjct 549 DDHHLHIAMSALDRRWFDAVPPGRPVYITAQGLLMYLPPQEVASLIADMAQRFPGASFCF 608
Query 191 DLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLRVPPGRGLW 250
D PRW + + G + + VP MP+ ++ ++ A + G+ V RG W
Sbjct 609 DHVPRWLSKQTLEGYKPGPNFTVPHMPWGLNRSEIAPALRDWAGIEQVETFDYRLYRG-W 667
Query 251 VNMALSTVYRLPVFDPLRPCLTLLEF 276
+ + +LP P +T F
Sbjct 668 RGLIFGWLSQLPFARERLPAITRAAF 693
>gi|121609388|ref|YP_997195.1| O-methyltransferase domain-containing protein [Verminephrobacter
eiseniae EF01-2]
gi|121554028|gb|ABM58177.1| O-methyltransferase domain protein [Verminephrobacter eiseniae
EF01-2]
Length=270
Score = 153 bits (387), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 88/220 (40%), Positives = 124/220 (57%), Gaps = 5/220 (2%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
LTGV +T L TL+ RA EA R D + D A + +SI +D+ + FG A R+ F
Sbjct 7 LTGVPQTMLWTLHNRATEALRPDGWLQDAEAARIYQSIPYDYDRDFGRPDGSHATRSAMF 66
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D A + +L HP TVV L GL+T F R D GQ RWL VD+P + +R R LP+S
Sbjct 67 DEALRPWLTAHPGGTVVELGCGLETQFQRCD----DGQVRWLGVDVPEAIAVRERYLPAS 122
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R SALD +W+D+VD + GVFITA+GL MY + L+ A+ Q++FD
Sbjct 123 ERYRHLGVSALDPAWLDTVDQSRGVFITAQGLFMYFEEADVRRLVTLIAECLSEAQLMFD 182
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNK 231
+ P+W++ + GL + YKVP MP+ + + A L+
Sbjct 183 VIPKWYSRKTVQGLWRTPHYKVPPMPWGLDRHEIAPLLRS 222
>gi|344343274|ref|ZP_08774143.1| putative O-methyltransferase [Marichromatium purpuratum 984]
gi|343805205|gb|EGV23102.1| putative O-methyltransferase [Marichromatium purpuratum 984]
Length=272
Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 97/268 (37%), Positives = 142/268 (53%), Gaps = 9/268 (3%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
LT V ET L TL+ RA+EA R D +I DP A+ + ++D+D+ + FGP +R+ F
Sbjct 9 LTDVPETMLWTLHNRASEAARADGVIRDPRALDIHRALDYDYERAFGPADYSHGVRSAIF 68
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D + +LD HP +V L EGL+T +RLD + WL+VDLP + +R R +
Sbjct 69 DAELRAFLDAHPDGVIVNLGEGLETQRFRLD----SDRALWLSVDLPESIAIRERFISPD 124
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R SALD W+D V V++TA+GL MY PE GL+ + A PG + FD
Sbjct 125 ARHLHLPMSALDTRWIDRVPSGRPVYVTAQGLFMYFDPEALAGLLRELATRLPGAWLAFD 184
Query 192 LPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQ-AADLVNKVPGVVAVRDLRVPPGRGLW 250
P W + + G + Y+ P+MP+ + + A L + VP +V V+DL RGL
Sbjct 185 HIPGWLSRRTLRGWWKTPHYRTPKMPWGIDRHRLAPTLRDWVPDLVEVQDLEFVAPRGL- 243
Query 251 VNMALS-TVYRLPVFDPLRPCLTLLEFS 277
AL+ V R+PV P + + F+
Sbjct 244 -TRALTWLVARVPVLRRYLPGIVRVRFA 270
>gi|113475372|ref|YP_721433.1| O-methyltransferase-like [Trichodesmium erythraeum IMS101]
gi|110166420|gb|ABG50960.1| O-methyltransferase-like [Trichodesmium erythraeum IMS101]
Length=282
Score = 150 bits (380), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 96/273 (36%), Positives = 139/273 (51%), Gaps = 21/273 (7%)
Query 10 RVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDF-AKFGPTGQ----GF 64
+ LTGV ET L TL RA EA R DAII D A+ + SID+D+ A FG + GF
Sbjct 7 KSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWRAMYTGF 66
Query 65 ALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLR 124
A+R+ FD +L +P T+V L EGL+T +R I Q WLTVD+P + +R
Sbjct 67 AIRSIIFDREINKFLSTYPDGTIVNLGEGLETHRFR----IAKEQGLWLTVDVPEAIKIR 122
Query 125 TRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFP 184
+ + R + SALD W D V VFITA+GL MYL E+ +I A TF
Sbjct 123 EQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQGLFMYLPLEEVKLIIQDIANTFN 182
Query 185 GGQMLFDLPPRWFA--GWSRLGLRTSLRYKVPRMPFSMSVAQAADLVN----KVPGVVAV 238
G ++FD+ P W + S G + + Y VP+MP+ ++ + +N + +V +
Sbjct 183 QGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIVDI 242
Query 239 RDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCL 271
P G W+++ + + F PL+ L
Sbjct 243 GYDNYPRGVMKWLSLLILS------FTPLKNIL 269
>gi|114327547|ref|YP_744704.1| polyketide synthase O-methyltransferase [Granulibacter bethesdensis
CGDNIH1]
gi|114315721|gb|ABI61781.1| polyketide synthase O-methyltransferase [Granulibacter bethesdensis
CGDNIH1]
Length=282
Score = 146 bits (368), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 80/217 (37%), Positives = 119/217 (55%), Gaps = 5/217 (2%)
Query 1 VSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDF-AKFGP 59
++A P R L G+ ET L TL+ RAAEA R D I+ DP A+ + ++ D+ A+FG
Sbjct 1 MNADIPRPIRPVLCGIPETTLWTLHDRAAEAARPDGILHDPHAIRMRNALMIDWIARFGA 60
Query 60 TGQGFALRARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPP 119
FA R+RA D +L +HP V+++ EGL+T R+D G WL+VDLP
Sbjct 61 ADGSFAGRSRAIDTLLTDWLSRHPDGMVISIGEGLETQSRRVD----NGTCTWLSVDLPE 116
Query 120 IVDLRTRLLPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQC 179
++ LR ++LP + R ALD W++++DP+ +GLLMY P + L+
Sbjct 117 VIALRRQMLPDTERFRSLGVDALDTGWLEAIDPSRPCLFLMQGLLMYFPPNRVAPLLRHM 176
Query 180 AQTFPGGQMLFDLPPRWFAGWSRLGLRTSLRYKVPRM 216
+ FP ++FD P WFA + GL + + VPRM
Sbjct 177 TKRFPASMLIFDTVPVWFATLTAHGLHKTPLFTVPRM 213
>gi|88705731|ref|ZP_01103441.1| Tetracenomycin polyketide synthesis O-methyltransferase tcmP
[Congregibacter litoralis KT71]
gi|88700244|gb|EAQ97353.1| Tetracenomycin polyketide synthesis O-methyltransferase tcmP
[Congregibacter litoralis KT71]
Length=273
Score = 144 bits (364), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 85/213 (40%), Positives = 118/213 (56%), Gaps = 7/213 (3%)
Query 12 ALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARA 70
LT V ET L TL++RA EA R D + DP AV + + +D+DF + FG + ALRA+
Sbjct 8 GLTDVPETMLWTLHSRAHEAMRPDGVFSDPKAVEIYQGLDYDFERNFGRSNPMAALRAQL 67
Query 71 FDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPS 130
FD +L++HP A+VV L EGL+T +RL+ PG W TVDLP + +R R +P+
Sbjct 68 FDQLVSAFLEEHPGASVVNLGEGLETQRYRLE-QTPG---EWFTVDLPEAIGIRERFIPA 123
Query 131 SPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLF 190
R A SA D +WM + V I A+GL MY Q + L+ A FP +LF
Sbjct 124 DARHQHIALSATDRAWMRCIPRDRPVCIAAQGLFMYFQEQDVRDLLGDIAAQFPRCHLLF 183
Query 191 DLPPRWFAGWSRL--GLRTSLRYKVPRMPFSMS 221
D+ P W + S L GL + Y+ P MP+ +
Sbjct 184 DVIPHWVSRASVLMGGLPLTRHYRTPVMPWGVH 216
>gi|343492493|ref|ZP_08730856.1| O-methyltransferase-like protein [Vibrio nigripulchritudo ATCC
27043]
gi|342827115|gb|EGU61513.1| O-methyltransferase-like protein [Vibrio nigripulchritudo ATCC
27043]
Length=272
Score = 142 bits (359), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 92/270 (35%), Positives = 139/270 (52%), Gaps = 14/270 (5%)
Query 13 LTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGFALRARAF 71
L V ET L TL+ RA EA R D++I D A+ + +SI++D+ K FG A+R+ F
Sbjct 7 LKEVPETMLWTLHNRANEAMREDSVIQDDKAIQIYQSINYDYEKSFGKADPSHAIRSLDF 66
Query 72 DMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSS 131
D +LD++P T+V L EGL+T +R+D + WL VDLP ++ R + +
Sbjct 67 DREISAFLDEYPDGTIVNLGEGLETQRFRID----NDKALWLCVDLPESIENREQFIQPD 122
Query 132 PRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD 191
R A SALD +W +SV VFI+A+GL MY EQ L+ Q F ++FD
Sbjct 123 SRHLHIALSALDLTWFESVPKDKPVFISAQGLFMYFAEEQVRSLLQAIEQNFDNWVVMFD 182
Query 192 LPPRWFAG--WSRLGLRTSLRYKVPRMPFSMSVAQAADLVNK-VPGVVAVRDL---RVPP 245
P W + S+ G + + YK P MP+ ++ +Q ++ +P V+VRD+ P
Sbjct 183 TIPAWLSKKTISQDGWQKTPDYKAPPMPWGVNRSQIRQTFSRWLPEHVSVRDIGYSTFPR 242
Query 246 GRGLWVNMALSTVYRLPVFDPLRPCLTLLE 275
G WV + ++ P P + LE
Sbjct 243 GIMKWVFLLFTST---PGLKNATPTIVKLE 269
>gi|296394826|ref|YP_003659710.1| O-methyltransferase domain-containing protein [Segniliparus rotundus
DSM 44985]
gi|296181973|gb|ADG98879.1| O-methyltransferase domain protein [Segniliparus rotundus DSM
44985]
Length=270
Score = 142 bits (359), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 79/224 (36%), Positives = 123/224 (55%), Gaps = 7/224 (3%)
Query 10 RVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVESIDFDFAK-FGPTGQGF-ALR 67
+ L G +ETA+ TL RA EA+R D+++DDP V + E+ID+ + + FG G +
Sbjct 3 EIELRGAAETAIWTLYTRAVEAQRPDSVLDDPTCVQVFEAIDYPYERTFGKDQSGIHGEK 62
Query 68 ARAFDMAAQHYLDQHPAATVVALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRL 127
+R FD Q +L ++P TVV L GL+T F R+D G W+ VDLP ++ +R R
Sbjct 63 SRIFDTVVQGWLAENPRGTVVELGAGLETEFHRVD----NGTVSWICVDLPEVIAVRNRF 118
Query 128 LPSSPRVSVCAQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQ 187
LP++ R A D SW D ++ AG V +TA+ LLM+L EQA L+ + FPG +
Sbjct 119 LPATERCRNVAADVRDLSWCDQIE-AGPVLVTAQSLLMFLSEEQARELVVAIVKKFPGAE 177
Query 188 MLFDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNK 231
++FD+ + + G + Y+ P + + + A LV +
Sbjct 178 IVFDVISPTVSKRTIKGYDLTEHYRFPVLHWGVKKKDIAALVRQ 221
Lambda K H
0.324 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 449018424576
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40