BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1159A

Length=94
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15840602|ref|NP_335639.1|  pterin-4-alpha-carbinolamine dehydr...   190    6e-47
gi|31792353|ref|NP_854846.1|  pterin-4-alpha-carbinolamine dehydr...   190    7e-47
gi|308398805|ref|ZP_07669387.1|  hypothetical protein TMLG_02840 ...   185    2e-45
gi|296170050|ref|ZP_06851653.1|  4a-hydroxytetrahydrobiopterin de...   150    9e-35
gi|342862050|ref|ZP_08718693.1|  pterin-4-alpha-carbinolamine deh...   149    1e-34
gi|118465216|ref|YP_880544.1|  pterin-4-alpha-carbinolamine dehyd...   147    4e-34
gi|41408721|ref|NP_961557.1|  pterin-4-alpha-carbinolamine dehydr...   147    5e-34
gi|48428207|sp|P61733.1|PHS_MYCPA  RecName: Full=Putative pterin-...   147    7e-34
gi|254774177|ref|ZP_05215693.1|  pterin-4-alpha-carbinolamine deh...   145    2e-33
gi|240171705|ref|ZP_04750364.1|  pterin-4-alpha-carbinolamine deh...   145    3e-33
gi|254818785|ref|ZP_05223786.1|  pterin-4-alpha-carbinolamine deh...   144    3e-33
gi|120405501|ref|YP_955330.1|  pterin-4-alpha-carbinolamine dehyd...   144    4e-33
gi|183984261|ref|YP_001852552.1|  hypothetical protein MMAR_4291 ...   143    8e-33
gi|315443208|ref|YP_004076087.1|  pterin-4-alpha-carbinolamine de...   142    2e-32
gi|118470021|ref|YP_889395.1|  pterin-4-alpha-carbinolamine dehyd...   141    3e-32
gi|126436844|ref|YP_001072535.1|  pterin-4-alpha-carbinolamine de...   140    4e-32
gi|108801008|ref|YP_641205.1|  pterin-4-alpha-carbinolamine dehyd...   139    1e-31
gi|118616758|ref|YP_905090.1|  pterin-4-alpha-carbinolamine dehyd...   138    3e-31
gi|15827790|ref|NP_302053.1|  pterin-4-alpha-carbinolamine dehydr...   133    1e-29
gi|169628400|ref|YP_001702049.1|  pterin-4-alpha-carbinolamine de...   122    2e-26
gi|257057092|ref|YP_003134924.1|  pterin-4-alpha-carbinolamine de...   105    3e-21
gi|333989787|ref|YP_004522401.1|  pterin-4-alpha-carbinolamine de...   102    2e-20
gi|325676461|ref|ZP_08156139.1|  4a-hydroxytetrahydrobiopterin de...   101    4e-20
gi|134097576|ref|YP_001103237.1|  pterin-4-alpha-carbinolamine de...   100    1e-19
gi|111022893|ref|YP_705865.1|  pterin-4-alpha-carbinolamine dehyd...  98.2    4e-19
gi|54026735|ref|YP_120977.1|  pterin-4-alpha-carbinolamine dehydr...  97.8    4e-19
gi|226365400|ref|YP_002783183.1|  pterin-4-alpha-carbinolamine de...  97.8    5e-19
gi|302530070|ref|ZP_07282412.1|  pterin-4-alpha-carbinolamine deh...  97.4    5e-19
gi|115373362|ref|ZP_01460661.1|  putative pterin-4-alpha-carbinol...  97.1    7e-19
gi|310818404|ref|YP_003950762.1|  pterin-4-alpha-carbinolamine de...  96.7    1e-18
gi|312195946|ref|YP_004016007.1|  transcriptional coactivator/pte...  96.3    1e-18
gi|256374893|ref|YP_003098553.1|  transcriptional coactivator/pte...  96.3    1e-18
gi|333921040|ref|YP_004494621.1|  Pterin-4-alpha-carbinolamine de...  95.1    3e-18
gi|108761711|ref|YP_634890.1|  putative pterin-4-alpha-carbinolam...  95.1    3e-18
gi|338532171|ref|YP_004665505.1|  putative pterin-4-alpha-carbino...  94.7    4e-18
gi|331694854|ref|YP_004331093.1|  transcriptional coactivator/pte...  93.2    1e-17
gi|72161949|ref|YP_289606.1|  pterin-4-alpha-carbinolamine dehydr...  92.4    2e-17
gi|284033418|ref|YP_003383349.1|  putative pterin-4-alpha-carbino...  92.0    3e-17
gi|311899088|dbj|BAJ31496.1|  putative pterin-4-alpha-carbinolami...  89.7    1e-16
gi|271968921|ref|YP_003343117.1|  pterin-4-alpha-carbinolamine de...  88.2    4e-16
gi|300789857|ref|YP_003770148.1|  pterin-4-alpha-carbinolamine de...  87.8    5e-16
gi|117929069|ref|YP_873620.1|  pterin-4-alpha-carbinolamine dehyd...  87.4    6e-16
gi|148654373|ref|YP_001274578.1|  transcriptional coactivator/pte...  87.4    7e-16
gi|330469903|ref|YP_004407646.1|  transcriptional coactivator/pte...  87.0    7e-16
gi|156744260|ref|YP_001434389.1|  transcriptional coactivator/pte...  86.3    2e-15
gi|296270646|ref|YP_003653278.1|  transcriptional coactivator/pte...  85.9    2e-15
gi|159898769|ref|YP_001545016.1|  transcriptional coactivator/pte...  85.9    2e-15
gi|284989647|ref|YP_003408201.1|  transcriptional coactivator/pte...  85.5    2e-15
gi|226228135|ref|YP_002762241.1|  putative pterin-4-alpha-carbino...  85.1    3e-15
gi|337769440|emb|CCB78153.1|  putative pterin-4-alpha-carbinolami...  84.7    4e-15


>gi|15840602|ref|NP_335639.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium tuberculosis 
CDC1551]
 gi|254231430|ref|ZP_04924757.1| hypothetical protein TBCG_01144 [Mycobacterium tuberculosis C]
 gi|298524657|ref|ZP_07012066.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium tuberculosis 
94_M4241A]
 23 more sequence titles
 Length=101

 Score =  190 bits (483),  Expect = 6e-47, Method: Compositional matrix adjust.
 Identities = 94/94 (100%), Positives = 94/94 (100%), Gaps = 0/94 (0%)

Query  1    MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
            MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI
Sbjct  8    MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  67

Query  61   RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
            RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA
Sbjct  68   RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  101


>gi|31792353|ref|NP_854846.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium bovis 
AF2122/97]
 gi|57116835|ref|YP_177641.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium tuberculosis 
H37Rv]
 gi|121637091|ref|YP_977314.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 54 more sequence titles
 Length=94

 Score =  190 bits (482),  Expect = 7e-47, Method: Compositional matrix adjust.
 Identities = 94/94 (100%), Positives = 94/94 (100%), Gaps = 0/94 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI
Sbjct  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA
Sbjct  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94


>gi|308398805|ref|ZP_07669387.1| hypothetical protein TMLG_02840 [Mycobacterium tuberculosis SUMu012]
 gi|308366597|gb|EFP55448.1| hypothetical protein TMLG_02840 [Mycobacterium tuberculosis SUMu012]
 gi|323720322|gb|EGB29418.1| hypothetical protein TMMG_01854 [Mycobacterium tuberculosis CDC1551A]
Length=92

 Score =  185 bits (469),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 91/92 (99%), Positives = 92/92 (100%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +LTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW
Sbjct  1   MLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  60

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RTVTFALVTHAVGGITENDIAMAHDIDAMFGA
Sbjct  61  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  92


>gi|296170050|ref|ZP_06851653.1| 4a-hydroxytetrahydrobiopterin dehydratase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295895260|gb|EFG74970.1| 4a-hydroxytetrahydrobiopterin dehydratase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=94

 Score =  150 bits (378),  Expect = 9e-35, Method: Compositional matrix adjust.
 Identities = 72/91 (80%), Positives = 79/91 (87%), Gaps = 0/91 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAAL DLNGW+R  G LRRSIKFP+F+AGIDAVRRV E AE  +HHPDIDI
Sbjct  1   MAVLTDEQVDAALPDLNGWERVDGALRRSIKFPSFLAGIDAVRRVGEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAM  91
           RWRTVTFALVTH+ GGITE D+AMA DID +
Sbjct  61  RWRTVTFALVTHSEGGITEKDVAMARDIDGI  91


>gi|342862050|ref|ZP_08718693.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium colombiense 
CECT 3035]
 gi|342130354|gb|EGT83669.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium colombiense 
CECT 3035]
Length=94

 Score =  149 bits (377),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 73/91 (81%), Positives = 79/91 (87%), Gaps = 0/91 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAAL DLNGW+RA G LRRSIKFP+F+AGIDAVRRV E AE  +HHPDIDI
Sbjct  1   MAVLTDEQVDAALPDLNGWERADGALRRSIKFPSFLAGIDAVRRVGEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAM  91
           RWRTVTFALVTH+ GGIT NDI MA DID +
Sbjct  61  RWRTVTFALVTHSEGGITNNDIDMARDIDGI  91


>gi|118465216|ref|YP_880544.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium avium 
104]
 gi|166219360|sp|A0QCA6.1|PHS_MYCA1 RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|118166503|gb|ABK67400.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium avium 
104]
Length=94

 Score =  147 bits (372),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 70/94 (75%), Positives = 82/94 (88%), Gaps = 0/94 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQ+DAAL DL+GW+RA G LRRSIKFP+F+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  1   MAVLTDEQIDAALPDLDGWERADGALRRSIKFPSFLDGIDAVRRVAEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RWRTVTFALVTH+ GGIT+ND+ MA DI+ + G+
Sbjct  61  RWRTVTFALVTHSEGGITQNDVDMARDINGIVGS  94


>gi|41408721|ref|NP_961557.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium avium 
subsp. paratuberculosis K-10]
 gi|41397079|gb|AAS04940.1| hypothetical protein MAP_2623 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=109

 Score =  147 bits (371),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 69/94 (74%), Positives = 82/94 (88%), Gaps = 0/94 (0%)

Query  1    MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
            MAVLTDEQ+DAA+ DL+GW+RA G LRRSIKFP+F+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  16   MAVLTDEQIDAAMPDLDGWERADGALRRSIKFPSFLDGIDAVRRVAEHAESKDHHPDIDI  75

Query  61   RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
            RWRTVTFALVTH+ GGIT+ND+ MA DI+ + G+
Sbjct  76   RWRTVTFALVTHSEGGITQNDVDMARDINGIVGS  109


>gi|48428207|sp|P61733.1|PHS_MYCPA RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|336458642|gb|EGO37604.1| pterin-4a-carbinolamine dehydratase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=94

 Score =  147 bits (370),  Expect = 7e-34, Method: Compositional matrix adjust.
 Identities = 69/94 (74%), Positives = 82/94 (88%), Gaps = 0/94 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQ+DAA+ DL+GW+RA G LRRSIKFP+F+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  1   MAVLTDEQIDAAMPDLDGWERADGALRRSIKFPSFLDGIDAVRRVAEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RWRTVTFALVTH+ GGIT+ND+ MA DI+ + G+
Sbjct  61  RWRTVTFALVTHSEGGITQNDVDMARDINGIVGS  94


>gi|254774177|ref|ZP_05215693.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=94

 Score =  145 bits (366),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 69/94 (74%), Positives = 81/94 (87%), Gaps = 0/94 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQ+DAAL DL+GW+RA G LRRSIKFP+F+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  1   MAVLTDEQIDAALPDLDGWERADGALRRSIKFPSFLDGIDAVRRVAEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
            WRTVTFALVTH+ GGIT+ND+ MA DI+ + G+
Sbjct  61  HWRTVTFALVTHSEGGITQNDVDMARDINGIVGS  94


>gi|240171705|ref|ZP_04750364.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium kansasii 
ATCC 12478]
Length=94

 Score =  145 bits (365),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 71/93 (77%), Positives = 78/93 (84%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAAL  L+GW+RA G LRRS+KFP F+ GIDAVRRVAE AE  NHHPDIDI
Sbjct  1   MAVLTDEQVDAALPGLDGWERAEGALRRSVKFPAFLDGIDAVRRVAEHAERTNHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RWRTVTFALVTH+ GGIT+ DI MA DID + G
Sbjct  61  RWRTVTFALVTHSEGGITQRDIDMARDIDGIVG  93


>gi|254818785|ref|ZP_05223786.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium intracellulare 
ATCC 13950]
Length=94

 Score =  144 bits (364),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 71/91 (79%), Positives = 80/91 (88%), Gaps = 0/91 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAAL DL+GW+RA G LRRSIKF +F+AGIDAVRRVAE AE  +HHPDIDI
Sbjct  1   MAVLTDEQVDAALPDLDGWERADGALRRSIKFGSFLAGIDAVRRVAEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAM  91
           RWRTVTFALVTH+ GGIT+NDI MA DI+ +
Sbjct  61  RWRTVTFALVTHSEGGITQNDIDMARDINGI  91


>gi|120405501|ref|YP_955330.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium vanbaalenii 
PYR-1]
 gi|166219366|sp|A1TDS4.1|PHS_MYCVP RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|119958319|gb|ABM15324.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium vanbaalenii 
PYR-1]
Length=93

 Score =  144 bits (364),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 70/93 (76%), Positives = 78/93 (84%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDAAL DLNGW+RA G LRRS+KF  F+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  1   MAVLTDEQVDAALPDLNGWERADGALRRSVKFSAFLDGIDAVRRVAEHAEAKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RWRTVTFALVTH+ GGIT+ D+ MA DID + G
Sbjct  61  RWRTVTFALVTHSEGGITDKDVQMARDIDGILG  93


>gi|183984261|ref|YP_001852552.1| hypothetical protein MMAR_4291 [Mycobacterium marinum M]
 gi|183177587|gb|ACC42697.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=103

 Score =  143 bits (361),  Expect = 8e-33, Method: Compositional matrix adjust.
 Identities = 71/93 (77%), Positives = 77/93 (83%), Gaps = 0/93 (0%)

Query  1    MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
            MAVLTDEQVDA L  LNGWQRA G LRRSIKF TF+ GIDAVRRVAE AE  +HHPDIDI
Sbjct  10   MAVLTDEQVDAELPGLNGWQRADGALRRSIKFATFLDGIDAVRRVAEHAESKDHHPDIDI  69

Query  61   RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
            RWRTVTF LVTH+ GGIT+NDI MA DI+ + G
Sbjct  70   RWRTVTFGLVTHSAGGITQNDIDMARDINGIVG  102


>gi|315443208|ref|YP_004076087.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. Spyr1]
 gi|315261511|gb|ADT98252.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. Spyr1]
Length=93

 Score =  142 bits (357),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 67/93 (73%), Positives = 77/93 (83%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTDEQVDA L +LNGW+RA G LRRS++FP F+ GIDAVRRV E AE  +HHPDIDI
Sbjct  1   MAVLTDEQVDAVLPELNGWERADGALRRSVEFPAFLDGIDAVRRVGEHAESKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RWRTVTFALVTH+ GGIT+ D+ MA DID + G
Sbjct  61  RWRTVTFALVTHSEGGITQKDLEMARDIDGILG  93


>gi|118470021|ref|YP_889395.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium smegmatis 
str. MC2 155]
 gi|166219362|sp|A0R2K7.1|PHS_MYCS2 RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|118171308|gb|ABK72204.1| putative pterin-4-alpha-carbinolamine dehydratase [Mycobacterium 
smegmatis str. MC2 155]
Length=94

 Score =  141 bits (355),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 67/93 (73%), Positives = 79/93 (85%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVL+++QVDAAL +L GW+RA G LRRS+KFPTF+ GIDAVRRVAE AEE +HHPDIDI
Sbjct  1   MAVLSNDQVDAALPNLPGWERAAGALRRSVKFPTFLDGIDAVRRVAEFAEEKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RWRTVTFALVTHA GGITE D+ MA +I+ +  
Sbjct  61  RWRTVTFALVTHAAGGITEKDVQMAEEINRILS  93


>gi|126436844|ref|YP_001072535.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. JLS]
 gi|166219363|sp|A3Q4G7.1|PHS_MYCSJ RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|126236644|gb|ABO00045.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. JLS]
Length=94

 Score =  140 bits (354),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 67/92 (73%), Positives = 78/92 (85%), Gaps = 0/92 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTD+QVDAAL +L GW+RA GVLRRS+KFP F+ GI+AVRRVAERAE  +HHPDIDI
Sbjct  1   MAVLTDDQVDAALPELGGWERADGVLRRSVKFPAFLDGIEAVRRVAERAEAKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMF  92
           RWRTVTF LVTH+ GGITE D+ MA +ID + 
Sbjct  61  RWRTVTFVLVTHSEGGITEKDLQMAREIDEIL  92


>gi|108801008|ref|YP_641205.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. MCS]
 gi|119870149|ref|YP_940101.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. KMS]
 gi|123178268|sp|Q1B4N5.1|PHS_MYCSS RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|166219364|sp|A1UKF3.1|PHS_MYCSK RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|108771427|gb|ABG10149.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. MCS]
 gi|119696238|gb|ABL93311.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. KMS]
Length=94

 Score =  139 bits (350),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 66/92 (72%), Positives = 77/92 (84%), Gaps = 0/92 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MAVLTD+QVDAAL +L GW+RA G LRRS+KFP F+ GI+AVRRVAERAE  +HHPDIDI
Sbjct  1   MAVLTDDQVDAALPELGGWERADGALRRSVKFPAFLDGIEAVRRVAERAEAKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMF  92
           RWRTVTF LVTH+ GGITE D+ MA +ID + 
Sbjct  61  RWRTVTFVLVTHSEGGITEKDLQMAREIDEIL  92


>gi|118616758|ref|YP_905090.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium ulcerans 
Agy99]
 gi|118568868|gb|ABL03619.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
Length=92

 Score =  138 bits (347),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 68/91 (75%), Positives = 75/91 (83%), Gaps = 0/91 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +LTDEQVDA L  LNGWQRA G LRRSIKF TF+  IDAVRRVAE AE  +HHPDIDIRW
Sbjct  1   MLTDEQVDAELPGLNGWQRADGALRRSIKFATFLDAIDAVRRVAEHAESKDHHPDIDIRW  60

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RTVTFALVTH+ GGIT+NDI MA DI+ + G
Sbjct  61  RTVTFALVTHSAGGITQNDIDMARDINGIVG  91


>gi|15827790|ref|NP_302053.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium leprae 
TN]
 gi|221230267|ref|YP_002503683.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium leprae 
Br4923]
 gi|18202767|sp|Q9CBX1.1|PHS_MYCLE RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|254782252|sp|B8ZRQ6.1|PHS_MYCLB RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|13093342|emb|CAC30454.1| conserved hypothetical protein [Mycobacterium leprae]
 gi|219933374|emb|CAR71598.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=94

 Score =  133 bits (334),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 66/93 (71%), Positives = 72/93 (78%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           M VLTDEQVDAAL DLN W+   G L RSIKFPTF+AGIDAV RVAE AE  +HHPDIDI
Sbjct  1   MTVLTDEQVDAALLDLNDWKHTDGALCRSIKFPTFLAGIDAVCRVAEHAETKDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           R+RTVTF LVTH   GIT+ DI MA DID + G
Sbjct  61  RYRTVTFILVTHYADGITKKDITMARDIDRLIG  93


>gi|169628400|ref|YP_001702049.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium abscessus 
ATCC 19977]
 gi|226699862|sp|B1MLG8.1|PHS_MYCA9 RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|169240367|emb|CAM61395.1| Putative pterin-4-alpha-carbinolamine dehydratase [Mycobacterium 
abscessus]
Length=94

 Score =  122 bits (306),  Expect = 2e-26, Method: Compositional matrix adjust.
 Identities = 58/93 (63%), Positives = 71/93 (77%), Gaps = 0/93 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           MA+LTD+Q++AAL  L GW R G  LRR++ F  F+ GIDAVRR+AE AE V+HHPDIDI
Sbjct  1   MALLTDDQINAALAGLPGWTREGDSLRRAVTFDAFLDGIDAVRRIAEHAESVDHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           RWRTVTF L TH+ GGIT+ D+A+A  ID   G
Sbjct  61  RWRTVTFVLSTHSEGGITDKDLALAETIDTQIG  93


>gi|257057092|ref|YP_003134924.1| pterin-4-alpha-carbinolamine dehydratase [Saccharomonospora viridis 
DSM 43017]
 gi|256586964|gb|ACU98097.1| pterin-4-alpha-carbinolamine dehydratase [Saccharomonospora viridis 
DSM 43017]
Length=96

 Score =  105 bits (261),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 50/87 (58%), Positives = 63/87 (73%), Gaps = 0/87 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+D+++D AL  L  W+R G  + RS +  +F   I+ V RVAERAE  NHHPDIDIRW
Sbjct  4   LLSDQRIDEALQGLPEWRRVGDAIERSAELASFPQAIEVVNRVAERAEAANHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDID  89
           RTVTF L TH+ GGITE DIA+A +ID
Sbjct  64  RTVTFRLSTHSHGGITEKDIALAGEID  90


>gi|333989787|ref|YP_004522401.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. JDM601]
 gi|333485754|gb|AEF35146.1| pterin-4-alpha-carbinolamine dehydratase [Mycobacterium sp. JDM601]
Length=86

 Score =  102 bits (253),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 57/86 (67%), Positives = 72/86 (84%), Gaps = 0/86 (0%)

Query  9   VDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWRTVTFA  68
           +DAAL DL+GW+R  G LRRS+KF +F+AGI+AVRR AERAE  +HHPDIDIRWRTVTFA
Sbjct  1   MDAALPDLDGWERTDGALRRSVKFDSFLAGIEAVRRAAERAEAADHHPDIDIRWRTVTFA  60

Query  69  LVTHAVGGITENDIAMAHDIDAMFGA  94
           LVTH+ GGIT+ D+AMA +I+ +  +
Sbjct  61  LVTHSEGGITDKDVAMAGEINRILAS  86


>gi|325676461|ref|ZP_08156139.1| 4a-hydroxytetrahydrobiopterin dehydratase [Rhodococcus equi ATCC 
33707]
 gi|325552639|gb|EGD22323.1| 4a-hydroxytetrahydrobiopterin dehydratase [Rhodococcus equi ATCC 
33707]
Length=96

 Score =  101 bits (251),  Expect = 4e-20, Method: Compositional matrix adjust.
 Identities = 48/87 (56%), Positives = 64/87 (74%), Gaps = 0/87 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+D ++DAAL +L  W+R G  L R+I+  +F A I  V RVAE AE +NHHPDIDIRW
Sbjct  4   LLSDTEIDAALTNLPHWRRDGASLTRTIESASFPAAIALVDRVAETAESMNHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDID  89
           RTVT++L TH+ GGIT +D+ +A  ID
Sbjct  64  RTVTYSLSTHSAGGITGSDLELARQID  90


>gi|134097576|ref|YP_001103237.1| pterin-4-alpha-carbinolamine dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|291009161|ref|ZP_06567134.1| pterin-4-alpha-carbinolamine dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133910199|emb|CAM00312.1| pterin-4-alpha-carbinolamine dehydratase [Saccharopolyspora erythraea 
NRRL 2338]
Length=102

 Score =  100 bits (248),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 45/92 (49%), Positives = 63/92 (69%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +LTD+Q+ +AL  L  W+   G L RS++  +F   I  V R+AE AE+ NHHPDID+RW
Sbjct  7   LLTDDQISSALEHLPEWRHEEGELTRSVELASFPQAIQVVNRIAEIAEQENHHPDIDVRW  66

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           R +TF  VTH+ GGIT+ D++MA +ID+   A
Sbjct  67  RNLTFHCVTHSKGGITQADVSMAQEIDSAIDA  98


>gi|111022893|ref|YP_705865.1| pterin-4-alpha-carbinolamine dehydratase [Rhodococcus jostii 
RHA1]
 gi|110822423|gb|ABG97707.1| 4a-hydroxytetrahydrobiopterin dehydratase [Rhodococcus jostii 
RHA1]
Length=94

 Score = 98.2 bits (243),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 47/91 (52%), Positives = 67/91 (74%), Gaps = 0/91 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+D ++D AL +L GW+RAG  L R+++ PTF   ++ VR+VAE AE  NHHPDIDIRW
Sbjct  4   LLSDGEIDTALAELPGWRRAGDSLVRTVESPTFPEAVELVRKVAEAAEAANHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           R VT+ L TH+ GG+T+ D+ +A  ID++ G
Sbjct  64  RKVTYTLSTHSAGGLTQLDLDLAAQIDSLAG  94


>gi|54026735|ref|YP_120977.1| pterin-4-alpha-carbinolamine dehydratase [Nocardia farcinica 
IFM 10152]
 gi|81373367|sp|Q5YQC8.1|PHS_NOCFA RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|54018243|dbj|BAD59613.1| putative molybdopterin biosynthesis protein [Nocardia farcinica 
IFM 10152]
Length=95

 Score = 97.8 bits (242),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 47/89 (53%), Positives = 60/89 (68%), Gaps = 0/89 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+DEQ+  AL DL  W R+G  + R+++  +F A I  V RVAE AE   HHPDIDIRW
Sbjct  5   LLSDEQIATALQDLPDWTRSGDEISRTVQAESFPAAIALVDRVAEAAERAGHHPDIDIRW  64

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAM  91
           RTVTF L TH+ GG+T  DI +A  ID +
Sbjct  65  RTVTFTLSTHSAGGLTGRDIDLARQIDEL  93


>gi|226365400|ref|YP_002783183.1| pterin-4-alpha-carbinolamine dehydratase [Rhodococcus opacus 
B4]
 gi|226243890|dbj|BAH54238.1| putative pterin-4-alpha-carbinolamine dehydratase [Rhodococcus 
opacus B4]
Length=94

 Score = 97.8 bits (242),  Expect = 5e-19, Method: Compositional matrix adjust.
 Identities = 47/91 (52%), Positives = 66/91 (73%), Gaps = 0/91 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+D ++D AL  L GWQRAG  L R+++ P+F   ++ VR+VAE AE  NHHPDIDIRW
Sbjct  4   LLSDGEIDTALAGLPGWQRAGDSLVRTVESPSFPEAVELVRKVAEAAEAANHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFG  93
           R VT+ L TH+ GG+T+ D+ +A  ID++ G
Sbjct  64  RKVTYTLSTHSAGGLTQLDLDLAAQIDSLAG  94


>gi|302530070|ref|ZP_07282412.1| pterin-4-alpha-carbinolamine dehydratase [Streptomyces sp. AA4]
 gi|302438965|gb|EFL10781.1| pterin-4-alpha-carbinolamine dehydratase [Streptomyces sp. AA4]
Length=96

 Score = 97.4 bits (241),  Expect = 5e-19, Method: Compositional matrix adjust.
 Identities = 46/92 (50%), Positives = 61/92 (67%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L D  VD AL  +  W+R    + R+ + P+F A I+ V RVAE AEE +HHPDIDIRW
Sbjct  4   LLNDSAVDQALGTVPEWRREDATIVRTAELPSFPAAIEVVDRVAELAEEADHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RT+ F L TH++GG+TE D A+A  ID +  A
Sbjct  64  RTLVFRLSTHSLGGLTERDFALARQIDEVLAA  95


>gi|115373362|ref|ZP_01460661.1| putative pterin-4-alpha-carbinolamine dehydratase [Stigmatella 
aurantiaca DW4/3-1]
 gi|115369661|gb|EAU68597.1| putative pterin-4-alpha-carbinolamine dehydratase [Stigmatella 
aurantiaca DW4/3-1]
Length=135

 Score = 97.1 bits (240),  Expect = 7e-19, Method: Compositional matrix adjust.
 Identities = 45/90 (50%), Positives = 59/90 (66%), Gaps = 0/90 (0%)

Query  3    VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
            +LT E +   L    GW+  GG++RR+ +FP F+ GI  V RVA+ AE  +HHPDIDIRW
Sbjct  40   LLTPEALQTFLTGHPGWKHEGGMIRRTYEFPAFLTGIAFVERVAQVAERADHHPDIDIRW  99

Query  63   RTVTFALVTHAVGGITENDIAMAHDIDAMF  92
            R VT ALVTH  GG+T  D  +A + D +F
Sbjct  100  RKVTLALVTHDAGGLTSRDTGLAAEADRLF  129


>gi|310818404|ref|YP_003950762.1| pterin-4-alpha-carbinolamine dehydratase [Stigmatella aurantiaca 
DW4/3-1]
 gi|309391476|gb|ADO68935.1| pterin-4-alpha-carbinolamine dehydratase [Stigmatella aurantiaca 
DW4/3-1]
Length=102

 Score = 96.7 bits (239),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 45/90 (50%), Positives = 59/90 (66%), Gaps = 0/90 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +LT E +   L    GW+  GG++RR+ +FP F+ GI  V RVA+ AE  +HHPDIDIRW
Sbjct  7   LLTPEALQTFLTGHPGWKHEGGMIRRTYEFPAFLTGIAFVERVAQVAERADHHPDIDIRW  66

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMF  92
           R VT ALVTH  GG+T  D  +A + D +F
Sbjct  67  RKVTLALVTHDAGGLTSRDTGLAAEADRLF  96


>gi|312195946|ref|YP_004016007.1| transcriptional coactivator/pterin dehydratase [Frankia sp. EuI1c]
 gi|311227282|gb|ADP80137.1| transcriptional coactivator/pterin dehydratase [Frankia sp. EuI1c]
Length=104

 Score = 96.3 bits (238),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 47/91 (52%), Positives = 61/91 (68%), Gaps = 0/91 (0%)

Query  4   LTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWR  63
           L+ +++   L  L  W  A G +RR++  P+F+AGI+ VRRVA  AEE++HHPDIDIRWR
Sbjct  7   LSTDEITEGLRGLPAWALADGAIRRTVTAPSFLAGIELVRRVAAVAEEMDHHPDIDIRWR  66

Query  64  TVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
            VTFAL TH  GGIT  D+  A  ID +  A
Sbjct  67  RVTFALSTHDAGGITVLDLEQARAIDGLAAA  97


>gi|256374893|ref|YP_003098553.1| transcriptional coactivator/pterin dehydratase [Actinosynnema 
mirum DSM 43827]
 gi|255919196|gb|ACU34707.1| transcriptional coactivator/pterin dehydratase [Actinosynnema 
mirum DSM 43827]
Length=97

 Score = 96.3 bits (238),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 47/92 (52%), Positives = 61/92 (67%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +LTD+Q+ A L DL  W   G  L R+   P+F A ID V RVA+ AE ++HHPDIDIRW
Sbjct  4   LLTDDQLTAELADLPEWTAQGVSLVRTADLPSFRAAIDVVDRVADVAERMDHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RT+ F   TH+ GGIT  D+++AH+ID    A
Sbjct  64  RTLVFHCSTHSAGGITTLDVSLAHEIDRALDA  95


>gi|333921040|ref|YP_004494621.1| Pterin-4-alpha-carbinolamine dehydratase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333483261|gb|AEF41821.1| Pterin-4-alpha-carbinolamine dehydratase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=97

 Score = 95.1 bits (235),  Expect = 3e-18, Method: Compositional matrix adjust.
 Identities = 46/89 (52%), Positives = 59/89 (67%), Gaps = 0/89 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           VL D+ VD AL  L+GW R+G  + R+I  P+F   I  V  VAE AE+ NHHPDIDIRW
Sbjct  4   VLEDKDVDTALEALDGWSRSGTAISRTITLPSFPRAIAFVSAVAEVAEDKNHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAM  91
           R VTF   TH+ GGIT+ D+ +A  I+ +
Sbjct  64  RKVTFTCSTHSEGGITQLDLDLARTINDL  92


>gi|108761711|ref|YP_634890.1| putative pterin-4-alpha-carbinolamine dehydratase [Myxococcus 
xanthus DK 1622]
 gi|108465591|gb|ABF90776.1| putative pterin-4-alpha-carbinolamine dehydratase [Myxococcus 
xanthus DK 1622]
Length=103

 Score = 95.1 bits (235),  Expect = 3e-18, Method: Compositional matrix adjust.
 Identities = 44/90 (49%), Positives = 61/90 (68%), Gaps = 0/90 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L  E + + L     W+  GG++RR+ + PTF+AGI  V +VA+ AE+ +HHPDIDIRW
Sbjct  7   LLAPEALQSFLSQHTEWKHEGGMIRRTFEAPTFLAGIAFVEQVAQAAEKADHHPDIDIRW  66

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMF  92
           R VT ALVTH  GG+T  D A+A + D +F
Sbjct  67  RKVTLALVTHDAGGLTARDTALATEADRLF  96


>gi|338532171|ref|YP_004665505.1| putative pterin-4-alpha-carbinolamine dehydratase [Myxococcus 
fulvus HW-1]
 gi|337258267|gb|AEI64427.1| putative pterin-4-alpha-carbinolamine dehydratase [Myxococcus 
fulvus HW-1]
Length=103

 Score = 94.7 bits (234),  Expect = 4e-18, Method: Compositional matrix adjust.
 Identities = 44/90 (49%), Positives = 62/90 (69%), Gaps = 0/90 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L  E + + L     W+  GG++RR+ + PTF+AGI  V +VA+ AE+ +HHPDIDIRW
Sbjct  7   LLAPEALQSFLSQHPEWKHEGGMIRRTYEAPTFLAGIAFVEQVAQAAEKADHHPDIDIRW  66

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMF  92
           R VT ALVTH  GG+T+ D A+A + D +F
Sbjct  67  RKVTLALVTHDAGGLTDRDTALAAEADRLF  96


>gi|331694854|ref|YP_004331093.1| transcriptional coactivator/pterin dehydratase [Pseudonocardia 
dioxanivorans CB1190]
 gi|326949543|gb|AEA23240.1| transcriptional coactivator/pterin dehydratase [Pseudonocardia 
dioxanivorans CB1190]
Length=98

 Score = 93.2 bits (230),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 46/92 (50%), Positives = 59/92 (65%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L D  + AAL DL GW+RAG  + R+ + P F   I  V  VA+ AE  +HHPDIDIRW
Sbjct  4   LLDDAAITAALADLPGWERAGDSIVRTAELPDFPTAIRVVGEVADDAERADHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RT+TF L TH+ GG+T  D A+A +I A   A
Sbjct  64  RTLTFRLSTHSAGGLTAKDTALAAEISARVAA  95


>gi|72161949|ref|YP_289606.1| pterin-4-alpha-carbinolamine dehydratase [Thermobifida fusca 
YX]
 gi|71915681|gb|AAZ55583.1| pterin-4-alpha-carbinolamine dehydratase [Thermobifida fusca 
YX]
Length=94

 Score = 92.4 bits (228),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 40/83 (49%), Positives = 58/83 (70%), Gaps = 0/83 (0%)

Query  9   VDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWRTVTFA  68
           +++A+H L  W+R G  + R++  P+F+ GI+ V RVA+ AEE  HHPDIDIR+ T+TF 
Sbjct  10  LESAMHRLPAWRREGQAITRTVTVPSFLDGIELVNRVAQAAEEAQHHPDIDIRYTTLTFT  69

Query  69  LVTHAVGGITENDIAMAHDIDAM  91
           L +H VG +TE D+ MA  ID +
Sbjct  70  LTSHDVGHVTERDLKMAARIDTL  92


>gi|284033418|ref|YP_003383349.1| putative pterin-4-alpha-carbinolamine dehydratase [Kribbella 
flavida DSM 17836]
 gi|283812711|gb|ADB34550.1| putative pterin-4-alpha-carbinolamine dehydratase [Kribbella 
flavida DSM 17836]
Length=95

 Score = 92.0 bits (227),  Expect = 3e-17, Method: Compositional matrix adjust.
 Identities = 45/88 (52%), Positives = 62/88 (71%), Gaps = 1/88 (1%)

Query  3   VLTDEQVDAALHD-LNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIR  61
           +LTD+Q+DAA+ D L  W+ A   L RS++ PTF+ GI  V  VA+ AE +NHHPDIDIR
Sbjct  4   LLTDDQIDAAIRDHLPAWKVAENALVRSVETPTFLDGIRLVATVAQLAESMNHHPDIDIR  63

Query  62  WRTVTFALVTHAVGGITENDIAMAHDID  89
           + T+TF + +H  GGIT +D+ +A  ID
Sbjct  64  YTTITFRVSSHEAGGITNDDLVLARHID  91


>gi|311899088|dbj|BAJ31496.1| putative pterin-4-alpha-carbinolamine dehydratase [Kitasatospora 
setae KM-6054]
Length=98

 Score = 89.7 bits (221),  Expect = 1e-16, Method: Compositional matrix adjust.
 Identities = 44/91 (49%), Positives = 58/91 (64%), Gaps = 0/91 (0%)

Query  4   LTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWR  63
           L +EQ+  AL +L  W R G  + R+ +  +F   I  V  VAE+AE ++HHPDIDIRWR
Sbjct  6   LNEEQLANALAELPEWTRTGDAITRTAETASFPTAIKVVDAVAEQAEALDHHPDIDIRWR  65

Query  64  TVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           T+TF L TH+ GG+T  DI +AH ID    A
Sbjct  66  TLTFLLTTHSAGGLTSLDITLAHLIDRALDA  96


>gi|271968921|ref|YP_003343117.1| pterin-4-alpha-carbinolamine dehydratase [Streptosporangium roseum 
DSM 43021]
 gi|270512096|gb|ACZ90374.1| putative pterin-4-alpha-carbinolamine dehydratase [Streptosporangium 
roseum DSM 43021]
Length=96

 Score = 88.2 bits (217),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 46/91 (51%), Positives = 57/91 (63%), Gaps = 0/91 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           M +L D  VD  L  +  W+R G  +RR+IK P F   I  V  VA  AE++NHHPDIDI
Sbjct  1   MDLLDDSAVDQRLTGVPEWRREGDEIRRTIKAPDFPTAIRIVDEVAVEAEKLNHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAM  91
           RWRT+  AL TH  GG+TE D  +A  IDA+
Sbjct  61  RWRTLHLALSTHDAGGLTEMDFTLAARIDAI  91


>gi|300789857|ref|YP_003770148.1| pterin-4-alpha-carbinolamine dehydratase [Amycolatopsis mediterranei 
U32]
 gi|299799371|gb|ADJ49746.1| pterin-4-alpha-carbinolamine dehydratase [Amycolatopsis mediterranei 
U32]
 gi|340531526|gb|AEK46731.1| pterin-4-alpha-carbinolamine dehydratase [Amycolatopsis mediterranei 
S699]
Length=94

 Score = 87.8 bits (216),  Expect = 5e-16, Method: Compositional matrix adjust.
 Identities = 42/92 (46%), Positives = 58/92 (64%), Gaps = 2/92 (2%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L D++ DA L     W R+G  + R ++  +F   I+ V RVAE AE  +HHPDIDIRW
Sbjct  4   ILNDDEADARLG--ADWTRSGAEISREVELASFPQAIEVVNRVAELAEAADHHPDIDIRW  61

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RT+TF L TH+ GG+T  D  +A  ID++  A
Sbjct  62  RTLTFRLSTHSAGGLTAKDFDLASQIDSVLAA  93


>gi|117929069|ref|YP_873620.1| pterin-4-alpha-carbinolamine dehydratase [Acidothermus cellulolyticus 
11B]
 gi|117649532|gb|ABK53634.1| pterin-4-alpha-carbinolamine dehydratase [Acidothermus cellulolyticus 
11B]
Length=99

 Score = 87.4 bits (215),  Expect = 6e-16, Method: Compositional matrix adjust.
 Identities = 43/92 (47%), Positives = 59/92 (65%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           +L+D QV  AL  L GW   G  + R++K  +F AGI  V  VAE AE ++HHPDIDIRW
Sbjct  4   LLSDAQVAEALAGLEGWHGNGKAISRTVKAESFPAGIRLVDAVAEVAESLDHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
            ++TF   TH+ GG+TE D+ +A  I+ +  A
Sbjct  64  TSITFTCATHSKGGVTELDLNLARRINDLVQA  95


>gi|148654373|ref|YP_001274578.1| transcriptional coactivator/pterin dehydratase [Roseiflexus sp. 
RS-1]
 gi|254782255|sp|A5UPS5.1|PHS_ROSS1 RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|148566483|gb|ABQ88628.1| pterin-4-alpha-carbinolamine dehydratase [Roseiflexus sp. RS-1]
Length=93

 Score = 87.4 bits (215),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 40/88 (46%), Positives = 55/88 (63%), Gaps = 0/88 (0%)

Query  4   LTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWR  63
           L+D +++  L DL GW R G  +R++ + P+F + I  V  VA  AE   HHPDIDIRWR
Sbjct  5   LSDAEIEERLGDLTGWTRQGNEIRKTFQLPSFPSAIAFVVNVAFLAEAAGHHPDIDIRWR  64

Query  64  TVTFALVTHAVGGITENDIAMAHDIDAM  91
            VT +L TH  GG+T+ D  +A  ID +
Sbjct  65  KVTLSLTTHDAGGLTQKDFDLATQIDEI  92


>gi|330469903|ref|YP_004407646.1| transcriptional coactivator/pterin dehydratase [Verrucosispora 
maris AB-18-032]
 gi|328812874|gb|AEB47046.1| transcriptional coactivator/pterin dehydratase [Verrucosispora 
maris AB-18-032]
Length=97

 Score = 87.0 bits (214),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 45/92 (49%), Positives = 57/92 (62%), Gaps = 0/92 (0%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRW  62
           VLT E V   L  L GW +    + R+++  +F   I  V RVA  AEE++HHPDIDIRW
Sbjct  4   VLTAEAVRDELGGLAGWSQDPAGITRTVELASFPDAIGLVDRVAATAEELDHHPDIDIRW  63

Query  63  RTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           RTVTF  VTH+ GG+T  DI +A  ID + G 
Sbjct  64  RTVTFRCVTHSAGGVTRRDIELARRIDEIVGG  95


>gi|156744260|ref|YP_001434389.1| transcriptional coactivator/pterin dehydratase [Roseiflexus castenholzii 
DSM 13941]
 gi|254782254|sp|A7NS25.1|PHS_ROSCS RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|156235588|gb|ABU60371.1| transcriptional coactivator/pterin dehydratase [Roseiflexus castenholzii 
DSM 13941]
Length=93

 Score = 86.3 bits (212),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 41/90 (46%), Positives = 55/90 (62%), Gaps = 0/90 (0%)

Query  2   AVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIR  61
           A+L D +++  L DL GW R G  +R++ + P+F + I  V  VA  AE   HHPDIDIR
Sbjct  3   ALLNDAEIEERLGDLTGWTRQGNEIRKTFQLPSFPSAIAFVVNVAFLAEAAGHHPDIDIR  62

Query  62  WRTVTFALVTHAVGGITENDIAMAHDIDAM  91
           WR VT +L TH  GG+T  D  +A  ID +
Sbjct  63  WRKVTLSLSTHDAGGLTGKDFDLAAQIDEI  92


>gi|296270646|ref|YP_003653278.1| transcriptional coactivator/pterin dehydratase [Thermobispora 
bispora DSM 43833]
 gi|296093433|gb|ADG89385.1| transcriptional coactivator/pterin dehydratase [Thermobispora 
bispora DSM 43833]
Length=89

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 40/82 (49%), Positives = 53/82 (65%), Gaps = 0/82 (0%)

Query  13  LHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWRTVTFALVTH  72
           ++D + W+R G  LRRS+  P F   I  V  +AE+AE +NHHPDIDIRWRT+ FAL TH
Sbjct  1   MYDASEWRRDGNTLRRSVVAPDFRTAIAIVNEIAEQAEALNHHPDIDIRWRTLHFALTTH  60

Query  73  AVGGITENDIAMAHDIDAMFGA  94
             G +T+ D  +A  ID +  A
Sbjct  61  DAGALTDLDYTLAARIDGILAA  82


>gi|159898769|ref|YP_001545016.1| transcriptional coactivator/pterin dehydratase [Herpetosiphon 
aurantiacus DSM 785]
 gi|226699861|sp|A9AXS2.1|PHS_HERA2 RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase; 
Short=PHS; AltName: Full=4-alpha-hydroxy-tetrahydropterin 
dehydratase; AltName: Full=Pterin carbinolamine dehydratase; 
Short=PCD
 gi|159891808|gb|ABX04888.1| transcriptional coactivator/pterin dehydratase [Herpetosiphon 
aurantiacus DSM 785]
Length=96

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 44/94 (47%), Positives = 55/94 (59%), Gaps = 0/94 (0%)

Query  1   MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDI  60
           M VL    +  AL   +GW    G + ++    TF   I+ VRR+A+ AEEVNHHPDIDI
Sbjct  1   MPVLAKAALQQALEQRSGWTVVDGQISKTYGLATFPFAIEFVRRIADAAEEVNHHPDIDI  60

Query  61  RWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           R+  VT AL TH   GITE D  +A  ID +F A
Sbjct  61  RYNKVTIALSTHDEKGITEKDFGLADTIDRIFAA  94


>gi|284989647|ref|YP_003408201.1| transcriptional coactivator/pterin dehydratase [Geodermatophilus 
obscurus DSM 43160]
 gi|284062892|gb|ADB73830.1| transcriptional coactivator/pterin dehydratase [Geodermatophilus 
obscurus DSM 43160]
Length=100

 Score = 85.5 bits (210),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 40/89 (45%), Positives = 60/89 (68%), Gaps = 0/89 (0%)

Query  4   LTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWR  63
           L  +++ AAL  L  W   G  +RRS++ P F   + A+ R+A  AE+++HHPD+D+RWR
Sbjct  10  LPPDELAAALSGLPLWSGDGEGIRRSVELPDFPDAVAALVRMAFVAEQLDHHPDVDLRWR  69

Query  64  TVTFALVTHAVGGITENDIAMAHDIDAMF  92
           T+   LVTH+ GG+TE D+ +A  IDA+F
Sbjct  70  TLHLTLVTHSAGGVTELDLELARRIDALF  98


>gi|226228135|ref|YP_002762241.1| putative pterin-4-alpha-carbinolamine dehydratase [Gemmatimonas 
aurantiaca T-27]
 gi|226091326|dbj|BAH39771.1| putative pterin-4-alpha-carbinolamine dehydratase [Gemmatimonas 
aurantiaca T-27]
Length=99

 Score = 85.1 bits (209),  Expect = 3e-15, Method: Compositional matrix adjust.
 Identities = 40/93 (44%), Positives = 57/93 (62%), Gaps = 0/93 (0%)

Query  2   AVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIR  61
           + L+D ++  AL  L GW R G  + +S  F TF AGI  + +VA+ AE + HHPDID+R
Sbjct  7   SALSDIEIQRALGALPGWSRKGDAICKSYHFATFPAGIAFLAKVADVAERLQHHPDIDVR  66

Query  62  WRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           +  V F L TH  GG+T+ D  +AH I+ +  A
Sbjct  67  YTRVQFVLSTHDAGGVTQKDFELAHQIETLASA  99


>gi|337769440|emb|CCB78153.1| putative pterin-4-alpha-carbinolamine dehydratase [Streptomyces 
cattleya NRRL 8057]
Length=101

 Score = 84.7 bits (208),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 41/95 (44%), Positives = 64/95 (68%), Gaps = 6/95 (6%)

Query  3   VLTDEQVDAALHDLNGWQRAGGVLRRSIK---FPTFMAGIDAVRRVAERAEEVNHHPDID  59
           +L+D Q+D A+ DL  W+R G  LRR+++   FPT +  +DAV   A   E++ HHPD+D
Sbjct  4   LLSDAQIDEAMADLKDWRREGNTLRRTVEAYDFPTAIRILDAV---AVETEKLGHHPDVD  60

Query  60  IRWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA  94
           +R++T+ F+L TH+VGG+T  D  +AH I+   G+
Sbjct  61  LRYKTLHFSLTTHSVGGLTVLDTELAHRIETAAGS  95



Lambda     K      H
   0.324    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 127354591080


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40