BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1167c
Length=201
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608307|ref|NP_215683.1| transcriptional regulatory protein ... 402 1e-110
gi|296170058|ref|ZP_06851661.1| TetR family transcriptional regu... 246 1e-63
gi|254774186|ref|ZP_05215702.1| transcriptional regulator, TetR ... 246 1e-63
gi|118467207|ref|YP_880554.1| TetR family transcriptional regula... 246 1e-63
gi|41408712|ref|NP_961548.1| hypothetical protein MAP2614 [Mycob... 246 2e-63
gi|336458651|gb|EGO37613.1| transcriptional regulator, tetR fami... 246 2e-63
gi|342862059|ref|ZP_08718702.1| TetR family transcriptional regu... 245 3e-63
gi|240171696|ref|ZP_04750355.1| transcriptional regulatory prote... 243 9e-63
gi|254818776|ref|ZP_05223777.1| transcriptional regulator, TetR ... 243 1e-62
gi|183984256|ref|YP_001852547.1| transcriptional regulatory prot... 238 3e-61
gi|296165632|ref|ZP_06848154.1| TetR family transcriptional regu... 201 4e-50
gi|343479090|gb|AEM44258.1| transcriptional regulator [unculture... 113 1e-23
gi|297202854|ref|ZP_06920251.1| transcriptional regulator [Strep... 107 7e-22
gi|290956943|ref|YP_003488125.1| transcriptional regulator [Stre... 107 7e-22
gi|134103747|ref|YP_001109408.1| TetR family transcriptional reg... 107 1e-21
gi|296270537|ref|YP_003653169.1| TetR family transcriptional reg... 107 1e-21
gi|336116107|ref|YP_004570873.1| putative TetR family transcript... 102 4e-20
gi|29828996|ref|NP_823630.1| TetR family transcriptional regulat... 101 6e-20
gi|302557991|ref|ZP_07310333.1| TetR-family transcriptional regu... 100 1e-19
gi|158317650|ref|YP_001510158.1| TetR family transcriptional reg... 100 1e-19
gi|302554615|ref|ZP_07306957.1| transcriptional regulator [Strep... 100 2e-19
gi|329939991|ref|ZP_08289273.1| transcriptional regulator [Strep... 99.8 2e-19
gi|256375014|ref|YP_003098674.1| TetR family transcriptional reg... 99.0 3e-19
gi|297191619|ref|ZP_06909017.1| transcriptional regulator [Strep... 99.0 4e-19
gi|302537358|ref|ZP_07289700.1| transcriptional regulator [Strep... 97.8 8e-19
gi|288916466|ref|ZP_06410843.1| transcriptional regulator, TetR ... 97.4 1e-18
gi|345003757|ref|YP_004806611.1| TetR family transcriptional reg... 97.1 1e-18
gi|328885536|emb|CCA58775.1| Transcriptional regulator, TetR fam... 97.1 1e-18
gi|297562463|ref|YP_003681437.1| regulatory protein TetR [Nocard... 97.1 1e-18
gi|32141274|ref|NP_733675.1| transcriptional regulator [Streptom... 97.1 1e-18
gi|29469216|gb|AAO65329.1| putative transcriptional regulator [S... 95.9 3e-18
gi|111220679|ref|YP_711473.1| TetR family transcriptional regula... 95.5 4e-18
gi|336178380|ref|YP_004583755.1| regulatory protein TetR [Franki... 95.1 4e-18
gi|86739419|ref|YP_479819.1| TetR family transcriptional regulat... 94.4 8e-18
gi|256377826|ref|YP_003101486.1| TetR family transcriptional reg... 92.0 4e-17
gi|256396574|ref|YP_003118138.1| TetR family transcriptional reg... 91.7 5e-17
gi|111222680|ref|YP_713474.1| TetR family transcriptional regula... 90.5 1e-16
gi|291302197|ref|YP_003513475.1| TetR family transcriptional reg... 89.7 2e-16
gi|337763767|emb|CCB72477.1| Transcriptional regulator, tetR fam... 89.0 4e-16
gi|291436843|ref|ZP_06576233.1| transcriptional regulator [Strep... 88.6 5e-16
gi|120403711|ref|YP_953540.1| TetR family transcriptional regula... 85.5 4e-15
gi|254387928|ref|ZP_05003165.1| tetR-family transcriptional regu... 85.1 5e-15
gi|253576276|ref|ZP_04853607.1| transcriptional regulator [Paeni... 84.7 7e-15
gi|326331593|ref|ZP_08197883.1| transcriptional regulator, TetR ... 82.8 3e-14
gi|258654123|ref|YP_003203279.1| TetR family transcriptional reg... 82.0 5e-14
gi|269127321|ref|YP_003300691.1| TetR family transcriptional reg... 82.0 5e-14
gi|296271211|ref|YP_003653843.1| TetR family transcriptional reg... 82.0 5e-14
gi|145223608|ref|YP_001134286.1| TetR family transcriptional reg... 80.1 2e-13
gi|300311794|ref|YP_003775886.1| TetR family transcription regul... 80.1 2e-13
gi|271969336|ref|YP_003343532.1| hypothetical protein Sros_8134 ... 79.7 2e-13
>gi|15608307|ref|NP_215683.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15840610|ref|NP_335647.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31792361|ref|NP_854854.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97]
80 more sequence titles
Length=201
Score = 402 bits (1034), Expect = 1e-110, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 1 MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWA 60
MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWA
Sbjct 1 MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWA 60
Query 61 GKRELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP 120
GKRELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP
Sbjct 61 GKRELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP 120
Query 121 ELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPD 180
ELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPD
Sbjct 121 ELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPD 180
Query 181 REQLTRIIDAMILTTGERRES 201
REQLTRIIDAMILTTGERRES
Sbjct 181 REQLTRIIDAMILTTGERRES 201
>gi|296170058|ref|ZP_06851661.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295895268|gb|EFG74978.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=232
Score = 246 bits (629), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 124/182 (69%), Positives = 147/182 (81%), Gaps = 0/182 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRWA K ELV AA+ + LPP
Sbjct 47 EVLERALYEATLAELAEVGYGGLTMEGIAARAHTGKAALYRRWATKCELVHAALVHTLPP 106
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
+PE R+ RSARENLL VF+A+ ++ AGKTA P M V QLLHEPE+RAIF ++V APRL+
Sbjct 107 LPEARSGRSARENLLTVFSAHRDVCAGKTAFPGMATVYQLLHEPEMRAIFADAVVAPRLQ 166
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTG 196
IVESILQ V G++DP +TP+TARIGPALI+QH L TGSPP+R +L+ I+DA+I G
Sbjct 167 IVESILQTAVAEGDLDPEMITPLTARIGPALINQHFLLTGSPPNRRELSLIVDAVIPPRG 226
Query 197 ER 198
R
Sbjct 227 SR 228
>gi|254774186|ref|ZP_05215702.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
Length=202
Score = 246 bits (629), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 122/183 (67%), Positives = 148/183 (81%), Gaps = 0/183 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRW K ELV AA+ +ALPP
Sbjct 17 EVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAALVFALPP 76
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
VPE R+ RSARENLLA+FTA ++LAGKTA P +E++ QLLHEPE+RAIF ++V PRL+
Sbjct 77 VPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHEPEMRAIFADAVVRPRLK 136
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTG 196
IVESILQ+ V+ G++DP ++TP+TARIG ALI+QH L GSPP+R +L I+D +I G
Sbjct 137 IVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPPNRRELALIVDTVIPPRG 196
Query 197 ERR 199
R
Sbjct 197 SDR 199
>gi|118467207|ref|YP_880554.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118168494|gb|ABK69391.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=230
Score = 246 bits (628), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 122/183 (67%), Positives = 148/183 (81%), Gaps = 0/183 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRW K ELV AA+ +ALPP
Sbjct 45 EVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAALVFALPP 104
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
VPE R+ RSARENLLA+FTA ++LAGKTA P +E++ QLLHEPE+RAIF ++V PRL+
Sbjct 105 VPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHEPEMRAIFADAVVRPRLK 164
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMILTTG 196
IVESILQ+ V+ G++DP ++TP+TARIG ALI+QH L GSPP+R +L I+D +I G
Sbjct 165 IVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPPNRRELALIVDTVIPPRG 224
Query 197 ERR 199
R
Sbjct 225 SDR 227
>gi|41408712|ref|NP_961548.1| hypothetical protein MAP2614 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41397070|gb|AAS04931.1| hypothetical protein MAP_2614 [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=230
Score = 246 bits (627), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 120/176 (69%), Positives = 146/176 (83%), Gaps = 0/176 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRW K ELV AA+ +ALPP
Sbjct 45 EVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAALVFALPP 104
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
VPE R+ RSARENLLA+FTA ++LAGKTA P +E++ QLLHEPE+RAIF ++V PRL+
Sbjct 105 VPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHEPEMRAIFADAVVRPRLK 164
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
IVESILQ+ V+ G++DP ++TP+TARIG ALI+QH L GSPP+R +L I+D +I
Sbjct 165 IVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPPNRRELALIVDTVI 220
>gi|336458651|gb|EGO37613.1| transcriptional regulator, tetR family [Mycobacterium avium subsp.
paratuberculosis S397]
Length=202
Score = 246 bits (627), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 120/176 (69%), Positives = 146/176 (83%), Gaps = 0/176 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRW K ELV AA+ +ALPP
Sbjct 17 EVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAALVFALPP 76
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
VPE R+ RSARENLLA+FTA ++LAGKTA P +E++ QLLHEPE+RAIF ++V PRL+
Sbjct 77 VPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHEPEMRAIFADAVVRPRLK 136
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
IVESILQ+ V+ G++DP ++TP+TARIG ALI+QH L GSPP+R +L I+D +I
Sbjct 137 IVESILQSAVQDGDLDPKSITPLTARIGSALINQHFLLNGSPPNRRELALIVDTVI 192
>gi|342862059|ref|ZP_08718702.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342130363|gb|EGT83678.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=203
Score = 245 bits (625), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 120/180 (67%), Positives = 145/180 (81%), Gaps = 0/180 (0%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRGEVLERALY+ATLAEL GYGGLTMEGIAARA TGKAALYRRW K ELV AA+ +
Sbjct 15 RRRGEVLERALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAALVF 74
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWA 132
ALPP+PE R+ RSARENLLA+FTA ++LAGKT P +++V QLLHEPE+RAIF ++V
Sbjct 75 ALPPLPELRSGRSARENLLAMFTAQRDLLAGKTGFPGLDVVHQLLHEPEMRAIFADAVVR 134
Query 133 PRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
PR+ IVESILQA + G++DP +TP+TARIG ALI+QH + GSPP+R L I+D +I
Sbjct 135 PRMAIVESILQAAIADGDLDPKVVTPLTARIGSALINQHFVLNGSPPNRRDLALIVDTVI 194
>gi|240171696|ref|ZP_04750355.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=185
Score = 243 bits (621), Expect = 9e-63, Method: Compositional matrix adjust.
Identities = 115/175 (66%), Positives = 144/175 (83%), Gaps = 0/175 (0%)
Query 18 VLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPPV 77
+LERALY ATLAEL + GYGGLTMEGIAARA TGKAALYRRWA K +LV AA+Q+A+PP+
Sbjct 1 MLERALYAATLAELAAVGYGGLTMEGIAARAHTGKAALYRRWANKHDLVHAALQHAVPPL 60
Query 78 PEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLRI 137
PR+ SARE+LL +FTA+ ++LAGKT P +EI+ Q +HEPELRAIF+N+V PRL++
Sbjct 61 AVPRSSGSARESLLTLFTAHRDVLAGKTDFPGLEIIGQFIHEPELRAIFVNAVVFPRLKV 120
Query 138 VESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
+ESILQA R G+IDPATLTP+TAR+GPALI+QH + TG+PP R L I+D +I
Sbjct 121 IESILQAAARDGQIDPATLTPLTARVGPALINQHFMLTGTPPSRRDLELIVDTVI 175
>gi|254818776|ref|ZP_05223777.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=204
Score = 243 bits (619), Expect = 1e-62, Method: Compositional matrix adjust.
Identities = 120/176 (69%), Positives = 144/176 (82%), Gaps = 0/176 (0%)
Query 17 EVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPP 76
EVLERALY+ATLAEL GYG LTMEGIAARA TGKAALYRRW K ELV AA+ +ALPP
Sbjct 19 EVLERALYEATLAELTEVGYGSLTMEGIAARAHTGKAALYRRWDTKCELVHAALVFALPP 78
Query 77 VPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLR 136
VPE R+ RSARENLLA+FTA ++LAGKTA PS++++ QLLHEPE+RAIF ++V PRL+
Sbjct 79 VPELRSGRSARENLLAMFTAQRDLLAGKTAFPSLDVIHQLLHEPEMRAIFADAVVRPRLQ 138
Query 137 IVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
IVESILQA V G++DP +TP+TARIG ALI+QH L GSPP+R +L I+D +I
Sbjct 139 IVESILQAAVDDGDLDPTAITPLTARIGSALINQHFLLNGSPPNRRELALIVDTVI 194
>gi|183984256|ref|YP_001852547.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183177582|gb|ACC42692.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=207
Score = 238 bits (608), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 124/185 (68%), Positives = 151/185 (82%), Gaps = 2/185 (1%)
Query 10 NPYR--RRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVL 67
PYR RRGEVLERALY ATLAEL + GYG LTMEGIAARAQTGKAALYRRWA K +LV
Sbjct 10 TPYRSRRRGEVLERALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQ 69
Query 68 AAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFI 127
AA+QYA+PP PEPR RSARENLL VFTA+ ++LAGKT P + + QL+HEPELRAIF
Sbjct 70 AALQYAVPPPPEPRPGRSARENLLTVFTAHRDVLAGKTEFPGLVAIGQLIHEPELRAIFA 129
Query 128 NSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRI 187
NSV PRL+I++S+L+A +R G++DP T+TP TARIGPAL++QH + TG+PP+R +L I
Sbjct 130 NSVVHPRLKIIDSVLRAAIREGDLDPDTVTPFTARIGPALMNQHFILTGTPPNRRELALI 189
Query 188 IDAMI 192
+D +I
Sbjct 190 VDTVI 194
>gi|296165632|ref|ZP_06848154.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295899003|gb|EFG78487.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=182
Score = 201 bits (512), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 98/170 (58%), Positives = 126/170 (75%), Gaps = 0/170 (0%)
Query 23 LYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPPVPEPRA 82
L+DATL EL GY LTM GIAARA+TGKA+LY RWA KREL+ AA+ A+PP+P P A
Sbjct 2 LFDATLTELADHGYTALTMGGIAARARTGKASLYSRWASKRELLCAALVSAVPPLPAPNA 61
Query 83 DRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLRIVESIL 142
RSARENLL V TA+ ++LAGKT P + +++QLLHEP LRAIF++SV PRL +++SIL
Sbjct 62 RRSARENLLGVLTAHRDLLAGKTGFPGLNVIAQLLHEPALRAIFVDSVIRPRLTVIDSIL 121
Query 143 QAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
+ V GEID A++TP + IGPALI QH + TG P R +L I+D ++
Sbjct 122 RTAVEQGEIDSASVTPWSVEIGPALISQHFILTGRAPTRRELILILDTVM 171
>gi|343479090|gb|AEM44258.1| transcriptional regulator [uncultured bacterium]
Length=204
Score = 113 bits (283), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 72/197 (37%), Positives = 103/197 (53%), Gaps = 5/197 (2%)
Query 1 MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWA 60
M S P RRRG+ L +A+YD+ LAEL G G LTMEGIA RA TGK LYRRWA
Sbjct 1 MATSDDPTTPPRRRRGDALLQAIYDSVLAELAEVGLGRLTMEGIAVRAGTGKMPLYRRWA 60
Query 61 GKRELVLAAVQYALPPVPEPRAD----RSARENLLAVFTANCEILAGKTALPSMEIVSQL 116
+L+L AV+ L V + RE+LL + +++AG ++S+
Sbjct 61 SPHDLLLEAVRNVLATVAASDGELPDTGDLREDLLILLNHPRDVMAGPVGPAISAVISER 120
Query 117 LHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTG 176
P L + ++ RI E++L+ GEI+P +TP GPAL+ L G
Sbjct 121 HRYPALVGAISSKIFGTHTRI-EAVLRRAAERGEINPERITPHLCLAGPALLILRYLVEG 179
Query 177 SPPDREQLTRIIDAMIL 193
PP+ ++ IID+++L
Sbjct 180 KPPELAEMAAIIDSVLL 196
>gi|297202854|ref|ZP_06920251.1| transcriptional regulator [Streptomyces sviceus ATCC 29083]
gi|197717339|gb|EDY61373.1| transcriptional regulator [Streptomyces sviceus ATCC 29083]
Length=207
Score = 107 bits (268), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 69/192 (36%), Positives = 99/192 (52%), Gaps = 2/192 (1%)
Query 4 SAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKR 63
+APA+ RRRG VLERA+ DA L +L + G+ GLTMEG+AA AQTGKAA+YRRW K
Sbjct 8 AAPAQTASPRRRGAVLERAILDAALEQLSTVGWNGLTMEGVAAGAQTGKAAVYRRWPSKE 67
Query 64 ELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGK--TALPSMEIVSQLLHEPE 121
+LV A++ LP E RE+LL + E + + +AL S+
Sbjct 68 DLVADALRAGLPRFEEAPDLGGVREDLLELCRQAREAMFSRPGSALRSVIHECDQTQAER 127
Query 122 LRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDR 181
A+ N V P ++++ I+ GV GE+ P PA++ GS D
Sbjct 128 FHAVIFNGVVEPSVKLLRQIITRGVGRGEVRPDAANDYVFDAIPAMMMYRSKMRGSEWDD 187
Query 182 EQLTRIIDAMIL 193
+ + +ID +L
Sbjct 188 QDVEEMIDRFML 199
>gi|290956943|ref|YP_003488125.1| transcriptional regulator [Streptomyces scabiei 87.22]
gi|260646469|emb|CBG69566.1| putative transcriptional regulator [Streptomyces scabiei 87.22]
Length=207
Score = 107 bits (268), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 66/198 (34%), Positives = 100/198 (51%), Gaps = 2/198 (1%)
Query 4 SAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKR 63
+APA+ RRRG VLERA+ DA L +L + G+ GLTMEG+AA AQTGKAA+YRRW K
Sbjct 8 AAPAQTASPRRRGAVLERAILDAALEQLSTVGWSGLTMEGVAAGAQTGKAAVYRRWPSKE 67
Query 64 ELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPE 121
+LV A++ LP E S RE+LL + + + ++ + L
Sbjct 68 DLVADALRAGLPRFEESPDLGSVREDLLELCRQARAAMFSRPGFALRSVIHECDNLQAER 127
Query 122 LRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDR 181
+ I V P +R++ +++ G+R GE+ P PA++ GS
Sbjct 128 FHGVIIGGVVEPTVRLLREVVERGIRRGEVRPDAANSYVFDAIPAMMMYRSKVCGSEWSE 187
Query 182 EQLTRIIDAMILTTGERR 199
+ +ID +++ RR
Sbjct 188 RDIEELIDQLMVPLLRRR 205
>gi|134103747|ref|YP_001109408.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|291007727|ref|ZP_06565700.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|133916370|emb|CAM06483.1| transcriptional regulator, TetR family [Saccharopolyspora erythraea
NRRL 2338]
Length=195
Score = 107 bits (267), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 66/181 (37%), Positives = 94/181 (52%), Gaps = 0/181 (0%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRGE L A+ ATL EL GY GLTME +A RA+TGKA++YRRW + EL + AV +
Sbjct 10 RRRGEALNAAILQATLDELSEVGYAGLTMERVAERARTGKASVYRRWPSRMELAIDAVYH 69
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWA 132
LP P + R +LLA+ + E LAG ++S +L + A
Sbjct 70 VLPDPSSPPDTGTLRGDLLALLRRHAETLAGPAGEALRGLLSDVLTDRSRTAELRQHSHG 129
Query 133 PRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMI 192
+ + I + V GEI +TP +G A++ QH LF G P E + I+D ++
Sbjct 130 AGRKAMGEITRRAVERGEIAAEAVTPRRIEVGHAMLRQHFLFQGVPIPDEVIVEIVDEVL 189
Query 193 L 193
+
Sbjct 190 V 190
>gi|296270537|ref|YP_003653169.1| TetR family transcriptional regulator [Thermobispora bispora
DSM 43833]
gi|296093324|gb|ADG89276.1| transcriptional regulator, TetR family [Thermobispora bispora
DSM 43833]
Length=213
Score = 107 bits (267), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 74/182 (41%), Positives = 95/182 (53%), Gaps = 8/182 (4%)
Query 16 GEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALP 75
G L+ A++ A L EL GY LTMEG+A RA+ GKA+LYRRW + ELV+ AV LP
Sbjct 17 GAALDEAIFQAVLDELAEVGYARLTMEGVAERARAGKASLYRRWPTRIELVMDAVYSRLP 76
Query 76 PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSV---W- 131
P S R +LLA+ N E LAG P+ E + LL E + I V W
Sbjct 77 DPSAPPDTGSLRGDLLALLRGNAEALAG----PAGEALRGLLSEALAGSDAIARVRRNWQ 132
Query 132 APRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAM 191
LRI IL+ V GEID + +T G AL+ H LF G P +T I+D +
Sbjct 133 GASLRITREILRRAVDRGEIDASAVTDRRLETGHALLRYHFLFHGPPIPEHVITEIVDEV 192
Query 192 IL 193
+L
Sbjct 193 LL 194
>gi|336116107|ref|YP_004570873.1| putative TetR family transcriptional regulator [Microlunatus
phosphovorus NM-1]
gi|334683885|dbj|BAK33470.1| putative TetR family transcriptional regulator [Microlunatus
phosphovorus NM-1]
Length=207
Score = 102 bits (253), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 64/185 (35%), Positives = 101/185 (55%), Gaps = 8/185 (4%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG VLE A+ +A LAEL GYG L+ME +A RA+ KA++Y RW + ELV
Sbjct 9 RRRGIVLEEAIREAALAELTEVGYGNLSMERVAQRARASKASVYSRWPSRAELVADLAHA 68
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP----ELRAIFIN 128
+P + R +L+++F A E+LAG +++++L +P E+R+ +
Sbjct 69 LMPDASDAPDTGDLRGDLISLFRAIAEVLAGPAGEALRGLLAEVLPDPARTLEIRSRSQH 128
Query 129 SVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRII 188
S R +E+++Q V GE+D +TP GPA++ Q LF G+P + + I+
Sbjct 129 SAR----RALETVVQRAVDRGEVDANAVTPRRLDAGPAMLRQQFLFAGAPIPDDIIVGIV 184
Query 189 DAMIL 193
D + L
Sbjct 185 DEVAL 189
>gi|29828996|ref|NP_823630.1| TetR family transcriptional regulator [Streptomyces avermitilis
MA-4680]
gi|29606101|dbj|BAC70165.1| putative TetR-family transcriptional regulator [Streptomyces
avermitilis MA-4680]
Length=207
Score = 101 bits (251), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 61/192 (32%), Positives = 97/192 (51%), Gaps = 2/192 (1%)
Query 4 SAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKR 63
+APA+ RRRG VLERA+ DA L +L + G+ GLTMEG+AA AQTGKAA+YRRW K
Sbjct 8 AAPAQTASLRRRGAVLERAILDAALEQLSTVGWNGLTMEGVAAGAQTGKAAVYRRWPSKE 67
Query 64 ELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELR 123
+LV+ A+Q LP E RE+LL + E + + L ++ + R
Sbjct 68 DLVVDALQAGLPRFDEVPDLGCVREDLLQLCRQAREAMFSRPGLALRSVIHECDSSQADR 127
Query 124 --AIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDR 181
+ + V P ++++ +I+ G+ GE+ PA++ S
Sbjct 128 FGGVILEGVVEPTVKLLRAIINRGIERGEVRSDAANGYVFDAIPAMMMYRTKMCASEWSE 187
Query 182 EQLTRIIDAMIL 193
+ ++D +++
Sbjct 188 RDIEELVDQLMV 199
>gi|302557991|ref|ZP_07310333.1| TetR-family transcriptional regulator [Streptomyces griseoflavus
Tu4000]
gi|302475609|gb|EFL38702.1| TetR-family transcriptional regulator [Streptomyces griseoflavus
Tu4000]
Length=207
Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 65/189 (35%), Positives = 98/189 (52%), Gaps = 14/189 (7%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG VLERA+ DA L +L + G+ GLTMEG+AA AQTGKAA+YRRW K +LV A++
Sbjct 17 RRRGAVLERAILDAALEQLSTVGWNGLTMEGVAAGAQTGKAAVYRRWPSKEDLVADALRA 76
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTAL--PSMEIVSQLLHEPE------LRA 124
LP S RE+LL + L + A+ PS V +++E + A
Sbjct 77 GLPQFDAVPDLGSVREDLLHL------CLRARDAMFSPSGFAVRSVIYECDTTQAERFHA 130
Query 125 IFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQL 184
+ + V P +R++ ++ G+ GE+ P PA++ GS L
Sbjct 131 VIFDGVVEPTIRMLREVITRGIERGEVRPDAANGYVFDAVPAMMMYRSKMCGSEWSDTDL 190
Query 185 TRIIDAMIL 193
++ID +++
Sbjct 191 EQMIDQLMV 199
>gi|158317650|ref|YP_001510158.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158113055|gb|ABW15252.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=200
Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 67/200 (34%), Positives = 103/200 (52%), Gaps = 5/200 (2%)
Query 3 VSAPAKANPY---RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRW 59
++ P A+P R R E + A+ ATL L GY G+TM+ +A RA+ GKA +YRRW
Sbjct 1 MTRPTLASPRPGGRPRDESRDGAIRQATLELLAEHGYDGVTMDRVATRAKAGKATIYRRW 60
Query 60 AGKRELVLAAV-QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLH 118
K LV+ ++ Q+ + P + S R ++ TA E++ + E+VS++
Sbjct 61 PSKVALVMDSITQFTEQTLQIPDSG-SLRTEMILFLTAFHELVGSEQGRIMAEMVSEMPR 119
Query 119 EPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSP 178
PELRA +W+ R + E I+ G+ GEI P + IG ALI Q +L TG P
Sbjct 120 NPELRAAVRERMWSQRKMMSEVIITRGIARGEITPEADPAILMEIGTALILQRLLITGDP 179
Query 179 PDREQLTRIIDAMILTTGER 198
D + ++D +I+ R
Sbjct 180 VDSAFIEHVVDDVIIAYASR 199
>gi|302554615|ref|ZP_07306957.1| transcriptional regulator [Streptomyces viridochromogenes DSM
40736]
gi|302472233|gb|EFL35326.1| transcriptional regulator [Streptomyces viridochromogenes DSM
40736]
Length=206
Score = 100 bits (248), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 58/192 (31%), Positives = 99/192 (52%), Gaps = 3/192 (1%)
Query 4 SAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKR 63
APA+ RRRG VLERA+ DA L +L + G+ GLTMEG+AA AQTGKAA+YRRW+ K
Sbjct 8 DAPAQ-TAARRRGAVLERAILDAALDQLSTVGWNGLTMEGVAAGAQTGKAAVYRRWSSKE 66
Query 64 ELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPE 121
+LV A++ LP E + RE+L+A+ + + + ++ + +
Sbjct 67 DLVADALRAGLPHFDEAPDEGGVREDLVALCRRARDAMFSRPGFALRSVIHECDTVQAER 126
Query 122 LRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDR 181
A+ + V P ++++ +++ G+ GE+ PA++ G
Sbjct 127 FHAVIFDGVVEPTIKMLREVIERGITRGEVRSDAANGYVFDAIPAMMMYRNKMCGCEWQD 186
Query 182 EQLTRIIDAMIL 193
++ +ID +++
Sbjct 187 HEIDEMIDELMV 198
>gi|329939991|ref|ZP_08289273.1| transcriptional regulator [Streptomyces griseoaurantiacus M045]
gi|329300817|gb|EGG44713.1| transcriptional regulator [Streptomyces griseoaurantiacus M045]
Length=206
Score = 99.8 bits (247), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 59/191 (31%), Positives = 98/191 (52%), Gaps = 3/191 (1%)
Query 5 APAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRE 64
APA+ P RRRG VLERA+ DA L +L + G+ TMEG+AA AQTGKAA+YRRW+ K E
Sbjct 9 APARTAP-RRRGAVLERAILDAALDQLSTVGWRDFTMEGVAAGAQTGKAAVYRRWSSKEE 67
Query 65 LVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPEL 122
LV A++ LP + S RE+L+A+ E + ++ + ++ + + +
Sbjct 68 LVAEALRAGLPDFRQAPDLGSVREDLIALCLWAREAMFSRSGVALRSVIHECDTVQVEQF 127
Query 123 RAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDRE 182
+ P ++++I+ G+ GE+ PA++ S +
Sbjct 128 HVLICEKFLVPTAELLQNIITRGIERGEVRAGAANDYVYDTIPAMMMYRTKMCDSEWSEQ 187
Query 183 QLTRIIDAMIL 193
+T ++D ++L
Sbjct 188 DITELVDRLML 198
>gi|256375014|ref|YP_003098674.1| TetR family transcriptional regulator [Actinosynnema mirum DSM
43827]
gi|255919317|gb|ACU34828.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM
43827]
Length=202
Score = 99.0 bits (245), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 74/196 (38%), Positives = 100/196 (52%), Gaps = 12/196 (6%)
Query 5 APAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRE 64
A A+ RRRG+ L A+Y ATL EL G L + IAA A GKA+LYRRWA E
Sbjct 3 ADARTTKPRRRGDALTGAIYLATLEELARTGLEPLAFDRIAAVAGAGKASLYRRWATPAE 62
Query 65 LVLAAVQYALP----PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP 120
LVLAA+ L P PEP + R +L+ + T +L +V+Q P
Sbjct 63 LVLAALTDPLTGFGEPTPEP-GTGTLRGDLVELLTGLARVLEQPHGRALRPLVAQRERHP 121
Query 121 ELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALI---HQHVLFTGS 177
EL A + V APR R++ +L+ V GE DPA +TP A +GP L+ H H
Sbjct 122 ELHARVVELVLAPRQRLLLRVLERAVERGEADPAAVTPRVATVGPRLVLTEHDH----RG 177
Query 178 PPDREQLTRIIDAMIL 193
P ++ I+D ++L
Sbjct 178 PVSAAEVEAIVDEVLL 193
>gi|297191619|ref|ZP_06909017.1| transcriptional regulator [Streptomyces pristinaespiralis ATCC
25486]
gi|197719360|gb|EDY63268.1| transcriptional regulator [Streptomyces pristinaespiralis ATCC
25486]
Length=199
Score = 99.0 bits (245), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 62/183 (34%), Positives = 94/183 (52%), Gaps = 2/183 (1%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG VLERA+ +A L +L + G+ GLTMEG+AA AQTGKAA+YRRW K +LV A++
Sbjct 2 RRRGPVLERAILEAALEQLSTVGWSGLTMEGVAASAQTGKAAVYRRWPSKEDLVADALEA 61
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKT--ALPSMEIVSQLLHEPELRAIFINSV 130
LP + E S RE+LL V + + +T AL S+ +++ V
Sbjct 62 GLPSLDEAVDHGSVREDLLHVCRRVRDAMFSRTGIALRSVLYECDTATAERFQSLINTRV 121
Query 131 WAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDA 190
P + ++ GVR G++ P + + P L+ GS + +ID
Sbjct 122 IEPSTELFREVVHRGVRRGDVRPDAACELVLDVIPGLLMYRSKICGSDWPDPDIAEMIDQ 181
Query 191 MIL 193
+++
Sbjct 182 VMV 184
>gi|302537358|ref|ZP_07289700.1| transcriptional regulator [Streptomyces sp. C]
gi|302446253|gb|EFL18069.1| transcriptional regulator [Streptomyces sp. C]
Length=201
Score = 97.8 bits (242), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 57/189 (31%), Positives = 98/189 (52%), Gaps = 2/189 (1%)
Query 7 AKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELV 66
A A P RRRG LERA+ D+ L +L + G+ LTME +AA A+TGKAA+YRRW+ K +LV
Sbjct 8 AGAAPVRRRGPALERAILDSALDQLSTVGWNALTMEAVAAGARTGKAAVYRRWSTKTDLV 67
Query 67 LAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPELRA 124
++ LP + E S RE+L V +I+ + + ++ + H R
Sbjct 68 AEVLRTGLPALGEIADHGSVREDLYTVCVRMRDIMRSQAGVALRAVLHECDHAHADLFRE 127
Query 125 IFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQL 184
+ + P ++ +L+ G+ G++ +P+ A + PA++ GS ++
Sbjct 128 VIWKGLHEPAHEVIRELLERGIERGDVRADATSPLLADVIPAMLMYRAKVCGSEWPDVEI 187
Query 185 TRIIDAMIL 193
+ID +++
Sbjct 188 AEMIDGVMV 196
>gi|288916466|ref|ZP_06410843.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288352066|gb|EFC86266.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=200
Score = 97.4 bits (241), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 64/192 (34%), Positives = 98/192 (52%), Gaps = 5/192 (2%)
Query 6 PAKANPY---RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGK 62
P A+P R R E + + A L L GY G+TM+ +A RA+ GKA +YRRW K
Sbjct 4 PTLASPRPGGRPRDESRDHTIRQAALELLAEHGYDGVTMDRVATRAKAGKATIYRRWPSK 63
Query 63 RELVLAAV-QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPE 121
LV+ A+ Q+ + AD S R+ L+A +A +++ E+VS++ PE
Sbjct 64 IALVMDALTQFTEQTLQVAEAD-SMRKELVAFLSAFADLVGHAQGRIMAEVVSEMPRNPE 122
Query 122 LRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDR 181
LRA +W R+ E I+ G+ GE+ + + +G A+I Q +L TG P D
Sbjct 123 LRAAVRERMWNQRMTTSEGIVNRGIARGEVGASADPNILVEVGTAMILQRLLITGDPVDG 182
Query 182 EQLTRIIDAMIL 193
+ I+D +IL
Sbjct 183 AFVEHIVDDVIL 194
>gi|345003757|ref|YP_004806611.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E]
gi|344319383|gb|AEN14071.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E]
Length=222
Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 72/190 (38%), Positives = 99/190 (53%), Gaps = 17/190 (8%)
Query 8 KANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVL 67
+ NP RRRGE LERA+ ATL EL GY GLTME +AARA+TGKA LYRRW G+ ELV+
Sbjct 17 RRNP-RRRGEELERAILAATLEELAEVGYAGLTMERVAARARTGKATLYRRWPGRAELVV 75
Query 68 AAV------QYALPPVPEPRADR-SARENLLAVFTA-NCEILAGKTALPSMEIVSQLLHE 119
A LP R D +A L A A + +IL G ++++++H+
Sbjct 76 DACAAHRLSDADLPDTGALRTDVITALRRLSARLAASHGDILRG--------LLTEVMHD 127
Query 120 PELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPP 179
PE + V ++++L V GEI+P A + L+ H L G+P
Sbjct 128 PEFARLVRERVHTAGPGAIQAVLWRAVARGEIEPWVPASRRATVAVDLLRNHYLLHGAPI 187
Query 180 DREQLTRIID 189
E +T I+D
Sbjct 188 PEEVVTEIVD 197
>gi|328885536|emb|CCA58775.1| Transcriptional regulator, TetR family [Streptomyces venezuelae
ATCC 10712]
Length=205
Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 63/198 (32%), Positives = 101/198 (52%), Gaps = 10/198 (5%)
Query 2 TVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAG 61
T +A + RRRG VLERA+ +ATL +L S G+ GLTMEG+A AQTGKAA+YRRW
Sbjct 7 TAAARPEGVSLRRRGPVLERAILEATLDQLSSVGWNGLTMEGVAVGAQTGKAAVYRRWPS 66
Query 62 KRELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPE 121
K +LV A+Q LP + E R++L + +++ K P + S +LHE +
Sbjct 67 KEDLVADALQAGLPTLDEAPDLGGVRDDLYELCRRVRDVMYSK---PGFALRS-VLHECD 122
Query 122 ------LRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFT 175
+ + V P R+ +LQ G+ G++ + + PA++
Sbjct 123 AEAAERFHGLIVTGVVEPSARLFRDVLQRGIARGDVRADANDDLVIDVIPAMMMYRSKVC 182
Query 176 GSPPDREQLTRIIDAMIL 193
S +++ +ID +++
Sbjct 183 ASEWPDDEIAELIDRIMV 200
>gi|297562463|ref|YP_003681437.1| regulatory protein TetR [Nocardiopsis dassonvillei subsp. dassonvillei
DSM 43111]
gi|296846911|gb|ADH68931.1| regulatory protein TetR [Nocardiopsis dassonvillei subsp. dassonvillei
DSM 43111]
Length=235
Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 61/183 (34%), Positives = 96/183 (53%), Gaps = 3/183 (1%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG L A+++A + E G L+MEGIA RA T K +LYRRW +++L A+ +
Sbjct 29 RRRGRELLNAIHEAVILEAADVGVARLSMEGIARRAGTAKTSLYRRWPTPGDILLDAMYH 88
Query 73 ALP-PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVW 131
P P P AD R +L+ + ++ +V++ H PEL F+ V+
Sbjct 89 TYPQEAPTPGAD-DLRGDLVRALMLLRDTMSRSLGQAMFSVVAEARHHPELYDRFVREVF 147
Query 132 APR-LRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDA 190
R R ++L+ G IDP+ +T +T IG A++ ++ + PPD E + RI+D
Sbjct 148 DSRGGRFTRTVLEHYADHGRIDPSRVTSVTDDIGEAMLIKYAMDHQGPPDGEYVERIVDE 207
Query 191 MIL 193
+IL
Sbjct 208 VIL 210
>gi|32141274|ref|NP_733675.1| transcriptional regulator [Streptomyces coelicolor A3(2)]
gi|289768651|ref|ZP_06528029.1| transcriptional regulator [Streptomyces lividans TK24]
gi|24429544|emb|CAD55235.1| transcriptional regulator [Streptomyces coelicolor A3(2)]
gi|289698850|gb|EFD66279.1| transcriptional regulator [Streptomyces lividans TK24]
Length=206
Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/186 (31%), Positives = 94/186 (51%), Gaps = 2/186 (1%)
Query 10 NPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAA 69
P RRRG VLERA+ +A L +L + G+ GLTMEG+AA AQTGKAA+YRRW K +LV A
Sbjct 13 TPSRRRGAVLERAILEAALDQLGTVGWNGLTMEGVAAGAQTGKAAVYRRWPSKEDLVADA 72
Query 70 VQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPELRAIFI 127
++ LP S RE+LL + + + + ++ + + A+ +
Sbjct 73 LRSGLPDFDTAPDRGSVREDLLELCRRARDAMFSRPGFALRSVIHECDTMQAERFHAVIL 132
Query 128 NSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRI 187
V P L+++ +++ G+ GE+ + PA++ S +L +
Sbjct 133 KGVVEPTLKLLREVIERGMERGEVRRDAVNGYVCDAIPAMMMYRSKICASEWTDRELEEM 192
Query 188 IDAMIL 193
ID +++
Sbjct 193 IDQLMI 198
>gi|29469216|gb|AAO65329.1| putative transcriptional regulator [Streptomyces murayamaensis]
Length=211
Score = 95.9 bits (237), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 95/183 (52%), Gaps = 2/183 (1%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG VLERA+ DATL +L + G+ LTMEG+AARAQTGKAA+YRRW+ K ELV A++
Sbjct 21 RRRGPVLERAILDATLEQLSTVGWNALTMEGVAARAQTGKAAVYRRWSSKEELVADALRS 80
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKT--ALPSMEIVSQLLHEPELRAIFINSV 130
LP + S RE+L + + + ++ AL S+ + + +
Sbjct 81 GLPDLDHADDHGSVREDLYRLCLRLRDAMYSRSGFALRSVLYECDAASAERFHGMVLQRM 140
Query 131 WAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDA 190
AP R+ ++ G+ G++ P + + P L+ GS E + ++D
Sbjct 141 VAPAQRLFAQAIRQGIARGDVRPDATAEVIFDVIPGLMMFRAKVRGSEWPDEAVAEMVDR 200
Query 191 MIL 193
+++
Sbjct 201 VLV 203
>gi|111220679|ref|YP_711473.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111148211|emb|CAJ59880.1| Putative TetR-family transcriptional regulator [Frankia alni
ACN14a]
Length=198
Score = 95.5 bits (236), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 65/195 (34%), Positives = 100/195 (52%), Gaps = 3/195 (1%)
Query 1 MTVSAPAKANPYRR-RGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRW 59
MT S+ A P R R E + A+ ATL L GY G+TM+ +AARA+ GKA +YRRW
Sbjct 1 MTQSSLASPRPGGRPRDESRDHAIRSATLDLLAELGYDGVTMDRVAARARAGKATIYRRW 60
Query 60 AGKRELVLAAVQ-YALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLH 118
K +V+ A+ +A +P P S R +++ T+ E + G E++S++
Sbjct 61 PSKLAMVMDAINAFAEERMPTPDTG-SLRLDIVEFLTSFHEAIRGGRGRIIAELISEMPR 119
Query 119 EPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSP 178
P+LR +W R +I++ + GE+ P + IG A+I Q VL TG
Sbjct 120 NPDLRNALRGGLWTQREASSHAIVEHAIARGELRPDIDHAILMEIGTAIILQRVLLTGET 179
Query 179 PDREQLTRIIDAMIL 193
DR L I+D +++
Sbjct 180 VDRPFLESIVDDIVI 194
>gi|336178380|ref|YP_004583755.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
gi|334859360|gb|AEH09834.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
Length=203
Score = 95.1 bits (235), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 71/201 (36%), Positives = 104/201 (52%), Gaps = 12/201 (5%)
Query 1 MTVSAPA------KANPYRRR-GEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKA 53
M+ +APA ++P RRR G L+ A++ A ++ GY LTM+ IAA A T KA
Sbjct 1 MSTTAPAVQGADRASHPSRRRRGPALQEAIFSAVFDQINEIGYARLTMDRIAAAAGTSKA 60
Query 54 ALYRRWAGKRELVLAAVQYALPPVPEPRADRSARENLLAVF-TANCEILAGKTALPSMEI 112
LYRRW + LVL A++ +LP VPEP A +S R +LL V T K + +
Sbjct 61 VLYRRWESRESLVLDALRESLPTVPEPPAGQSLRADLLHVLETVRSAFTVTKGT--TFHL 118
Query 113 VSQLLHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHV 172
V+ + RA+ V+ P R++ +L GEI +T + A IGPAL+
Sbjct 119 VAAEAGG-DCRALADERVFVPAHRVILDVLGRAAGWGEIRAELVTDLIAGIGPALLRSQA 177
Query 173 LFTGSPPDREQLTRIIDAMIL 193
+ G PD +T I+D ++L
Sbjct 178 I-DGPVPDPATVTAIVDEILL 197
>gi|86739419|ref|YP_479819.1| TetR family transcriptional regulator [Frankia sp. CcI3]
gi|86566281|gb|ABD10090.1| transcriptional regulator, TetR family [Frankia sp. CcI3]
Length=383
Score = 94.4 bits (233), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 61/182 (34%), Positives = 96/182 (53%), Gaps = 2/182 (1%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQ- 71
R R E ++A+ ATL L GY G+TM+ +A RA+ GKA +YRRW K LV+ AV
Sbjct 199 RPRDESRDQAIRTATLDLLAEVGYDGVTMDRVATRARAGKATIYRRWPSKLALVMDAVNA 258
Query 72 YALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVW 131
+ +P P + S R ++L T+ + + G E++S++ P LR +W
Sbjct 259 FTEQRMPAP-DNGSLRLDILEFLTSFHDAIRGDRGRILAELISEMPRNPGLRDALRRGLW 317
Query 132 APRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAM 191
R E+I++ G+ GE+ P + +G A+I Q VL TG P D+ L I+D +
Sbjct 318 MQRQASSEAIIERGIARGEVRPDVDRTVLIELGTAVILQRVLLTGDPVDQTFLEMIVDDI 377
Query 192 IL 193
++
Sbjct 378 VI 379
>gi|256377826|ref|YP_003101486.1| TetR family transcriptional regulator [Actinosynnema mirum DSM
43827]
gi|255922129|gb|ACU37640.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM
43827]
Length=206
Score = 92.0 bits (227), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 62/189 (33%), Positives = 94/189 (50%), Gaps = 12/189 (6%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRGE LERA+ DA EL+ GY LT++G+AARA+T K +YRRW + E+VLAA
Sbjct 7 RRRGEELERAILDAVWDELDEVGYDRLTIDGVAARARTSKPVIYRRWPSRAEMVLAAWLK 66
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSME------IVSQLLHEPELRAIF 126
P P P R +LLA+F+ +AG++ L + + + H PE+ +
Sbjct 67 RAPSWPGPEDRGDLRTDLLALFSG----IAGQSGLGAARAGDRTGMAWEAFHNPEVVVLV 122
Query 127 INSVWAPR--LRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQL 184
+ + P ++ +++ V GE+ P L R+ LI L P R L
Sbjct 123 SDKLLCPSPLGHALDGVVERAVGRGELPPLELPARVKRVPLDLIRSESLTRCGPLSRRVL 182
Query 185 TRIIDAMIL 193
++D + L
Sbjct 183 EELVDDVFL 191
>gi|256396574|ref|YP_003118138.1| TetR family transcriptional regulator [Catenulispora acidiphila
DSM 44928]
gi|256362800|gb|ACU76297.1| transcriptional regulator, TetR family [Catenulispora acidiphila
DSM 44928]
Length=228
Score = 91.7 bits (226), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 63/196 (33%), Positives = 97/196 (50%), Gaps = 12/196 (6%)
Query 3 VSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGK 62
V+ P A P R+R + AL A L L GY LT++ +AARA GKA YRRWAGK
Sbjct 7 VTEPGHA-PGRKRDASRDDALCQAALEVLADVGYDRLTIDAVAARAGAGKATCYRRWAGK 65
Query 63 RELVLAAV--QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPS---MEIVSQLL 117
ELV+ AV A P +P+ + R +L+ + C G A + +VS L+
Sbjct 66 AELVVDAVGRMKAQPELPDT---GTLRGDLVEL---TCHFHEGDDAFRTDVQAGLVSGLV 119
Query 118 HEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGS 177
+ +LR +F APR + + V GEI P + + + P+++ ++ TG
Sbjct 120 RDAKLREVFAEHFIAPRKEVFRVVFDRAVARGEIAPVADYDLLSDVVPSMVFHQMMLTGR 179
Query 178 PPDREQLTRIIDAMIL 193
P + +++D +IL
Sbjct 180 APGPAFVHKVLDQIIL 195
>gi|111222680|ref|YP_713474.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111150212|emb|CAJ61907.1| Putative transcriptional regulator (TetR-family) [Frankia alni
ACN14a]
Length=202
Score = 90.5 bits (223), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 64/198 (33%), Positives = 100/198 (51%), Gaps = 9/198 (4%)
Query 1 MTVSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWA 60
MT +A A RRRG+ L A++DA +L + GY LTM+ +AA A T K LYRRWA
Sbjct 1 MTGAARTGAVATRRRGDGLLAAIFDAVFDQLRTVGYANLTMDRVAAAAGTSKTVLYRRWA 60
Query 61 GKRELVLAAVQYALP---PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL- 116
K +++ AV+Y LP VP R+ LL A+ G ++++VS
Sbjct 61 AKEDMIADAVRYRLPNPGDVPLTGDVRADVHALLRCVQASFSATRGT----ALQLVSAEA 116
Query 117 -LHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFT 175
P +R I+ V P +R++ +L+ GEI P + + + A GPA++ Q+ L
Sbjct 117 GCGRPAVRQTIIDHVVEPCVRLIGEVLRRAAERGEIRPESASELVAASGPAMLVQYSLIR 176
Query 176 GSPPDREQLTRIIDAMIL 193
E + ++D ++L
Sbjct 177 EPIVPDEFVAAVVDQIVL 194
>gi|291302197|ref|YP_003513475.1| TetR family transcriptional regulator [Stackebrandtia nassauensis
DSM 44728]
gi|290571417|gb|ADD44382.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis
DSM 44728]
Length=196
Score = 89.7 bits (221), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 63/183 (35%), Positives = 91/183 (50%), Gaps = 3/183 (1%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG L A+++A + EL G G LTMEGIA R+ K +LYRRW L++ A++
Sbjct 8 RRRGAELVNAIHEAAIDELNEVGIGRLTMEGIARRSGAAKTSLYRRWPDTHALLIEALRE 67
Query 73 ALP-PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPEL-RAIFINSV 130
+P P P AD R +L+A C+ + A IV+ PE + +F
Sbjct 68 RMPQETPSPGAD-DLRGDLIAALQLLCDWMMTPAARAVSAIVAGSGAHPEFTKRVFEEVF 126
Query 131 WAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDA 190
A R ++L+ GEIDP +TP+ A IG AL+ + + + P L I+D
Sbjct 127 EAKGSRFTLTVLRHYADRGEIDPERVTPVVADIGEALVFKFSMDRFAMPAESDLAAIVDE 186
Query 191 MIL 193
IL
Sbjct 187 AIL 189
>gi|337763767|emb|CCB72477.1| Transcriptional regulator, tetR family [Streptomyces cattleya
NRRL 8057]
Length=208
Score = 89.0 bits (219), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 64/172 (38%), Positives = 90/172 (53%), Gaps = 11/172 (6%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQ- 71
RRRG L RA++ ATL EL G+ L+ + IA+ A TGKA+LYRRW+ ELVLAA+
Sbjct 18 RRRGASLTRAIHLATLTELAENGFDKLSFDKIASAAGTGKASLYRRWSTPAELVLAALTD 77
Query 72 --YALPPVPEPRADRSARENLLAVFTANCEILA----GKTALPSMEIVSQLLHEPELRAI 125
EPR + R +L A+ L G+ LP +++Q PEL A
Sbjct 78 PVCGFGDAAEPRTG-TLRGDLTALLNGFARTLEHQPHGRALLP---LITQRPRHPELYAE 133
Query 126 FINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGS 177
V PR R + ++L+ GE DP +TP+ A +GP L+ +L G+
Sbjct 134 VRRLVIEPRQRWITALLREAAERGEADPGAVTPLVAAVGPRLVVAALLDHGT 185
>gi|291436843|ref|ZP_06576233.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672]
gi|291339738|gb|EFE66694.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672]
Length=207
Score = 88.6 bits (218), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 60/184 (33%), Positives = 92/184 (50%), Gaps = 4/184 (2%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG V ERA+ DA L +L + G+ GLT+EG+AA A+TGKAA+YRRW K +LV A++
Sbjct 17 RRRGAVRERAILDAALEQLSAVGWSGLTVEGVAAGARTGKAAVYRRWPSKEDLVADALR- 75
Query 73 ALPPVPEPRADR-SARENLLAVFTANCEILAGKTALPSMEIVSQL--LHEPELRAIFINS 129
A PP E DR S E+LL + + + ++ L +V + +
Sbjct 76 AGPPRFEAAPDRGSVHEDLLVLCRRARDAMFSQSGLAVRAVVHECDATQAERFHGVIFEG 135
Query 130 VWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIID 189
V P L ++ +++ G GE+ P PA++ GS L +ID
Sbjct 136 VVDPTLTMLREVIELGAERGEVRPDAANGYVFDAIPAMMMYRSKMCGSEWTDADLEEMID 195
Query 190 AMIL 193
+++
Sbjct 196 RLMV 199
>gi|120403711|ref|YP_953540.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119956529|gb|ABM13534.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=192
Score = 85.5 bits (210), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 57/185 (31%), Positives = 91/185 (50%), Gaps = 8/185 (4%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELV----LA 68
RRRG L+ A+ A L L G G+TM+ +A AQT K LYRRW +R L+ L
Sbjct 3 RRRGAELDAAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLG 62
Query 69 AVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFIN 128
A P V R ++LAV A + G +A + + +PEL A F
Sbjct 63 IATSAFPTVDTG----GFRGDMLAVLRAWAALFTGDSAALMRSAIGAVTADPELAATFRT 118
Query 129 SVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRII 188
V R + +++I+ GV+ GE+ + +G +++ +L +G P D E +TR++
Sbjct 119 DVIGARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDDEVVTRLV 178
Query 189 DAMIL 193
D +++
Sbjct 179 DEVLI 183
>gi|254387928|ref|ZP_05003165.1| tetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|326446192|ref|ZP_08220926.1| TetR family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|197701652|gb|EDY47464.1| tetR-family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
Length=197
Score = 85.1 bits (209), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 66/186 (36%), Positives = 91/186 (49%), Gaps = 9/186 (4%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAA-VQ 71
RRRGE LE A+ DA EL GY LT + +A RA T K LYRRWA KR+LV AA V+
Sbjct 3 RRRGEALEAAILDAAWDELNERGYTNLTTDSVARRAGTSKPVLYRRWADKRKLVEAAVVR 62
Query 72 YALPPVPEPRADRSARENLLAVFTANCE----ILAGKTALPSMEIVSQLLHEPELRAIFI 127
+ + P S R +L+A T E +LA + L + ELR + I
Sbjct 63 RNVTQLTVPADTGSLRGDLIATLTGASERQGPVLAQLSLLLAGYFAETETSFTELREMII 122
Query 128 NSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRI 187
+ R + I++ + GEIDP+ LTP A + L+ + T P E + I
Sbjct 123 AGRRSGR----DEIMERAIARGEIDPSRLTPRIAALPFDLLRGETMMTLRPVAPEVIEEI 178
Query 188 IDAMIL 193
+D + L
Sbjct 179 VDTIFL 184
>gi|253576276|ref|ZP_04853607.1| transcriptional regulator [Paenibacillus sp. oral taxon 786 str.
D14]
gi|251844403|gb|EES72420.1| transcriptional regulator [Paenibacillus sp. oral taxon 786 str.
D14]
Length=190
Score = 84.7 bits (208), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 64/183 (35%), Positives = 88/183 (49%), Gaps = 10/183 (5%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG LE A+ A EL G+ LT+EG+AARAQT K +YRRW + ELVLAA+
Sbjct 12 RRRGAELEGAILQAAWDELMEIGFHHLTIEGVAARAQTSKPVIYRRWPNREELVLAAILN 71
Query 73 ALP--PVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSV 130
LP VP+ RS LL + + KT M +VS + P F + +
Sbjct 72 HLPTVSVPDTGNLRSDVLLLLNELNEMLQQIGPKTIHGLMSVVSDI---P-----FSDIL 123
Query 131 WAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDA 190
R + IL + GEI P +TP R+ L+ +L T P + + I+D
Sbjct 124 NFRRTNTMTVILDRAIERGEIRPEKVTPRITRLPVDLVRHELLITLEPVSMKTIEEIVDE 183
Query 191 MIL 193
+ L
Sbjct 184 IFL 186
>gi|326331593|ref|ZP_08197883.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
gi|325950849|gb|EGD42899.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium
Broad-1]
Length=202
Score = 82.8 bits (203), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 49/174 (29%), Positives = 80/174 (46%), Gaps = 1/174 (0%)
Query 20 ERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALPPVPE 79
E+ ++DAT+ L GY LTM+ +A RA+ KA LYRRW GK +LV+ A+ P+
Sbjct 24 EQEIFDATIDILAELGYDRLTMDAVAGRAKASKATLYRRWNGKAQLVIEALTSTKEPMTA 83
Query 80 PRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFINSVWAPRLRIVE 139
P RE+LL F + + +V+ + + E F V P+ I
Sbjct 84 PDTG-DLREDLLGAFCGMGGLTDQRQIAIFGSVVTAISRDAEFAEAFRRGVVGPKKAIAT 142
Query 140 SILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRIIDAMIL 193
+ + GE+ + + P ++ H G PP E + +++D +IL
Sbjct 143 EMFRRAQERGELRDDLDLDLISSALPGIVLHHTFLLGEPPTTELIAKVVDQLIL 196
>gi|258654123|ref|YP_003203279.1| TetR family transcriptional regulator [Nakamurella multipartita
DSM 44233]
gi|258557348|gb|ACV80290.1| transcriptional regulator, TetR family [Nakamurella multipartita
DSM 44233]
Length=245
Score = 82.0 bits (201), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 68/183 (38%), Positives = 97/183 (54%), Gaps = 13/183 (7%)
Query 4 SAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKR 63
+APA P R R ++RA+ ATL GY L+ME +AARA GKA +YRRW GK+
Sbjct 36 AAPACRRPGRPRERRVDRAIIAATLEIFADEGYHALSMESVAARAGVGKATIYRRWPGKK 95
Query 64 ELVLAAVQY-------ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQL 116
ELV+ A+ A +PE DR R L + T + + LAG+ LP M + S
Sbjct 96 ELVIDALATLNDDLLAARQQLPERTVDR-IRAILRHLATRDTDSLAGRI-LPRMVVYS-- 151
Query 117 LHEPELRAIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTAR--IGPALIHQHVLF 174
+ +P+L A + + V PR + + IL+ GVR GE+ P + A +GP ++ L
Sbjct 152 VSQPDLYAEYYHRVITPRRQWLHGILREGVRRGELRPDLDVEVAALAIVGPTMLPTRGLG 211
Query 175 TGS 177
T S
Sbjct 212 TDS 214
>gi|269127321|ref|YP_003300691.1| TetR family transcriptional regulator [Thermomonospora curvata
DSM 43183]
gi|268312279|gb|ACY98653.1| transcriptional regulator, TetR family [Thermomonospora curvata
DSM 43183]
Length=203
Score = 82.0 bits (201), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 60/190 (32%), Positives = 94/190 (50%), Gaps = 5/190 (2%)
Query 6 PAKANPYRRRGEVLERALYDATLAEL-ESAGYGGLTMEGIAARAQTGKAALYRRWAGKRE 64
P A P R R + A+ ATL L E AG G++ME +AARA GK+ +YRRW K
Sbjct 11 PEPARPGRPRSARADEAILQATLELLAEEAGVAGISMEAVAARAGVGKSTVYRRWPNKER 70
Query 65 LVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRA 124
L++ A+ P+P+P A S R++LLA+ A C + K ++ PEL A
Sbjct 71 LIVDALAALKRPLPDP-AGGSVRDDLLALAEAMCRERSAKHGRCLWNVLGGADKYPELLA 129
Query 125 IFINSVWAPRLRIVESILQAGVRSGEI--DPATLTPMTARIGPALIHQHVLFTGSPPDRE 182
+ V PR I+ +L+ GV +GE+ D + +G + +PP+ +
Sbjct 130 RYHREVIEPRREIIRRVLRRGVETGELRADLDVEAAIEMLVGAMTLQSRAPAATAPPE-D 188
Query 183 QLTRIIDAMI 192
R++D ++
Sbjct 189 LAERVVDTLL 198
>gi|296271211|ref|YP_003653843.1| TetR family transcriptional regulator [Thermobispora bispora
DSM 43833]
gi|296093998|gb|ADG89950.1| transcriptional regulator, TetR family [Thermobispora bispora
DSM 43833]
Length=213
Score = 82.0 bits (201), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 61/187 (33%), Positives = 93/187 (50%), Gaps = 11/187 (5%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRG+ LE AL A EL AGYG LTME +A RA T +A LYRRW GK +L +AA+++
Sbjct 8 RRRGKALEDALLSAAWEELSEAGYGALTMERVAVRAGTSRAVLYRRWPGKADLAIAAIRH 67
Query 73 ALPPVPEPRADR-SARENLLAVFTANCEILAGKTALPSMEIVSQLLHE-----PELRAIF 126
+ P P D + R++L+A+ + A+ ++ L E ELR +
Sbjct 68 HVETNPLPVPDTGNLRDDLIALLRSMTRRRGELAAMIGAQL-GGLFAEAGTTPAELRELI 126
Query 127 INSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTR 186
+ + R+ E + GE+DP + + L+ +L T P E++T
Sbjct 127 MRGNRSSSRRVYERAAE----RGELDPERIPEHVLAMPFDLVRHDMLMTFEPVPDERITA 182
Query 187 IIDAMIL 193
I+D + L
Sbjct 183 IVDELFL 189
>gi|145223608|ref|YP_001134286.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|145216094|gb|ABP45498.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
Length=210
Score = 80.1 bits (196), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 56/185 (31%), Positives = 92/185 (50%), Gaps = 5/185 (2%)
Query 11 PYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV 70
P + R E L TL +L+ GY LT+E +A +A+ KA LYRRW K +LVLAA
Sbjct 15 PLKSRRTAREAQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLVLAAF 74
Query 71 QYA--LPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPELRAIFIN 128
L VP PR S R++LL V + C+ A + A +++++ H P+LR +
Sbjct 75 VEGTRLAAVP-PRTG-SLRDDLLRVGASVCQ-QACEHASTMRAVLNEMSHNPDLRKAMQD 131
Query 129 SVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRII 188
+++ +L V+ GEID ++ + P + L + PP + + ++
Sbjct 132 EFVHQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLKSVRTLV 191
Query 189 DAMIL 193
D ++L
Sbjct 192 DKVLL 196
>gi|300311794|ref|YP_003775886.1| TetR family transcription regulator protein [Herbaspirillum seropedicae
SmR1]
gi|300074579|gb|ADJ63978.1| TetR family transcription regulator protein [Herbaspirillum seropedicae
SmR1]
Length=239
Score = 80.1 bits (196), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 51/149 (35%), Positives = 78/149 (53%), Gaps = 3/149 (2%)
Query 3 VSAPAKANPYRRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGK 62
+S PA RRR V A+ DAT LE G+ L++EG+AARA GKA +YR W K
Sbjct 42 ISDPATG---RRRNAVSHDAILDATYVMLEEIGFDKLSLEGVAARAGVGKATIYRWWPNK 98
Query 63 RELVLAAVQYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEPEL 122
L + A+ A+ P+P S+R ++ ++L GK+ E+++ EPE
Sbjct 99 SALAMEALLRAVEPMPPIGDSGSSRTDIELHMLQLSQLLRGKSGRVVREMIALAQFEPES 158
Query 123 RAIFINSVWAPRLRIVESILQAGVRSGEI 151
+ IF ++ PR + S+L+ G + GE
Sbjct 159 KRIFNDNYLEPRRLALVSVLRRGAQRGEF 187
>gi|271969336|ref|YP_003343532.1| hypothetical protein Sros_8134 [Streptosporangium roseum DSM
43021]
gi|270512511|gb|ACZ90789.1| hypothetical protein Sros_8134 [Streptosporangium roseum DSM
43021]
Length=203
Score = 79.7 bits (195), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/186 (33%), Positives = 90/186 (49%), Gaps = 9/186 (4%)
Query 13 RRRGEVLERALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQY 72
RRRGE L A+Y A L E+ G G LTM+GI RA T + LYRRW+ E++L A+ Y
Sbjct 9 RRRGEELTNAIYTAVLEEVAEVGVGRLTMDGIGRRAATARTTLYRRWSDPVEVLLDAL-Y 67
Query 73 ALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHE----PELRAIFIN 128
+ PV EP ++L +++ P+ V+ +L + P++
Sbjct 68 HMHPVEEP---TPGADDLRGDLIRALQLMVTWALSPAGRAVAAILTDPKGAPQVSEALFE 124
Query 129 SVWAPR-LRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVLFTGSPPDREQLTRI 187
V+A R ++L+ G LTP+ IG AL+ + +L TG P +L I
Sbjct 125 RVFANRGGTFTSTVLRHYAERGHFPADLLTPVVVDIGEALVTKRLLDTGRPLAAAELEAI 184
Query 188 IDAMIL 193
+D IL
Sbjct 185 VDQAIL 190
Lambda K H
0.319 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 217214446392
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40