BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1188

Length=329
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15608328|ref|NP_215704.1|  proline dehydrogenase [Mycobacteriu...   650    0.0   
gi|289446777|ref|ZP_06436521.1|  proline dehydrogenase [Mycobacte...   647    0.0   
gi|340626202|ref|YP_004744654.1|  putative proline dehydrogenase ...   645    0.0   
gi|289753257|ref|ZP_06512635.1|  proline dehydrogenase [Mycobacte...   579    2e-163
gi|183984224|ref|YP_001852515.1|  proline dehydrogenase, PutA [My...   489    2e-136
gi|118616697|ref|YP_905029.1|  proline dehydrogenase, PutA [Mycob...   486    2e-135
gi|240169049|ref|ZP_04747708.1|  proline dehydrogenase, PutA [Myc...   474    6e-132
gi|108800989|ref|YP_641186.1|  L-proline dehydrogenase [Mycobacte...   449    2e-124
gi|296170087|ref|ZP_06851689.1|  proline dehydrogenase [Mycobacte...   444    9e-123
gi|41408690|ref|NP_961526.1|  hypothetical protein MAP2592c [Myco...   443    2e-122
gi|342862075|ref|ZP_08718718.1|  hypothetical protein MCOL_24411 ...   439    3e-121
gi|118464208|ref|YP_880577.1|  proline dehydrogenase [Mycobacteri...   439    4e-121
gi|169628424|ref|YP_001702073.1|  proline dehydrogenase [Mycobact...   430    1e-118
gi|118467796|ref|YP_889365.1|  proline dehydrogenase [Mycobacteri...   425    4e-117
gi|254822925|ref|ZP_05227926.1|  hypothetical protein MintA_23559...   422    3e-116
gi|120405477|ref|YP_955306.1|  proline dehydrogenase [Mycobacteri...   422    4e-116
gi|325676444|ref|ZP_08156122.1|  proline dehydrogenase [Rhodococc...   370    2e-100
gi|111017371|ref|YP_700343.1|  proline dehydrogenase [Rhodococcus...   368    7e-100
gi|312138853|ref|YP_004006189.1|  proline dehydrogenase [Rhodococ...   367    1e-99 
gi|336120703|ref|YP_004575489.1|  proline dehydrogenase [Microlun...   366    3e-99 
gi|229489119|ref|ZP_04382985.1|  proline dehydrogenase [Rhodococc...   362    5e-98 
gi|226308192|ref|YP_002768152.1|  proline dehydrogenase [Rhodococ...   356    2e-96 
gi|226365423|ref|YP_002783206.1|  proline dehydrogenase [Rhodococ...   355    8e-96 
gi|226362365|ref|YP_002780143.1|  proline dehydrogenase [Rhodococ...   354    1e-95 
gi|111022915|ref|YP_705887.1|  proline dehydrogenase [Rhodococcus...   352    6e-95 
gi|72160838|ref|YP_288495.1|  L-proline dehydrogenase [Thermobifi...   338    5e-91 
gi|311898942|dbj|BAJ31350.1|  putative proline dehydrogenase [Kit...   338    8e-91 
gi|297559062|ref|YP_003678036.1|  proline dehydrogenase [Nocardio...   337    1e-90 
gi|343927217|ref|ZP_08766695.1|  putative proline dehydrogenase [...   336    3e-90 
gi|134098552|ref|YP_001104213.1|  proline dehydrogenase [Saccharo...   335    6e-90 
gi|336120452|ref|YP_004575237.1|  proline dehydrogenase [Microlun...   332    6e-89 
gi|302525803|ref|ZP_07278145.1|  proline dehydrogenase [Streptomy...   330    1e-88 
gi|54024324|ref|YP_118566.1|  putative proline dehydrogenase [Noc...   330    2e-88 
gi|262201272|ref|YP_003272480.1|  proline dehydrogenase [Gordonia...   328    8e-88 
gi|317509148|ref|ZP_07966773.1|  proline dehydrogenase [Segnilipa...   325    8e-87 
gi|256375223|ref|YP_003098883.1|  proline dehydrogenase [Actinosy...   324    1e-86 
gi|84494994|ref|ZP_00994113.1|  proline dehydrogenase [Janibacter...   324    2e-86 
gi|119714744|ref|YP_921709.1|  L-proline dehydrogenase [Nocardioi...   320    2e-85 
gi|330470601|ref|YP_004408344.1|  proline dehydrogenase [Verrucos...   318    5e-85 
gi|300784568|ref|YP_003764859.1|  proline dehydrogenase [Amycolat...   318    6e-85 
gi|296395172|ref|YP_003660056.1|  proline dehydrogenase [Segnilip...   317    2e-84 
gi|256397454|ref|YP_003119018.1|  Proline dehydrogenase [Catenuli...   314    1e-83 
gi|284034267|ref|YP_003384198.1|  proline dehydrogenase [Kribbell...   311    7e-83 
gi|329936823|ref|ZP_08286502.1|  proline dehydrogenase [Streptomy...   310    2e-82 
gi|297202562|ref|ZP_06919959.1|  proline dehydrogenase [Streptomy...   310    3e-82 
gi|302522085|ref|ZP_07274427.1|  proline dehydrogenase [Streptomy...   306    2e-81 
gi|295836357|ref|ZP_06823290.1|  proline dehydrogenase [Streptomy...   306    2e-81 
gi|318061799|ref|ZP_07980520.1|  putative proline dehydrogenase [...   306    2e-81 
gi|318076679|ref|ZP_07984011.1|  putative proline dehydrogenase [...   306    3e-81 
gi|291454326|ref|ZP_06593716.1|  proline dehydrogenase [Streptomy...   306    4e-81 


>gi|15608328|ref|NP_215704.1| proline dehydrogenase [Mycobacterium tuberculosis H37Rv]
 gi|15840631|ref|NP_335668.1| proline dehydrogenase family protein [Mycobacterium tuberculosis 
CDC1551]
 gi|31792381|ref|NP_854874.1| proline dehydrogenase [Mycobacterium bovis AF2122/97]
 72 more sequence titles
 Length=329

 Score =  650 bits (1677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 329/329 (100%), Positives = 329/329 (100%), Gaps = 0/329 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR
Sbjct  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR
Sbjct  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR
Sbjct  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH
Sbjct  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL
Sbjct  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300

Query  301  RRLAERPANLAFFLRALTDRRRARGCAER  329
            RRLAERPANLAFFLRALTDRRRARGCAER
Sbjct  301  RRLAERPANLAFFLRALTDRRRARGCAER  329


>gi|289446777|ref|ZP_06436521.1| proline dehydrogenase [Mycobacterium tuberculosis CPHL_A]
 gi|289419735|gb|EFD16936.1| proline dehydrogenase [Mycobacterium tuberculosis CPHL_A]
Length=329

 Score =  647 bits (1668),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 328/329 (99%), Positives = 328/329 (99%), Gaps = 0/329 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR
Sbjct  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR
Sbjct  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR
Sbjct  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH
Sbjct  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DPVIIAAVPGITRESG SQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL
Sbjct  241  DPVIIAAVPGITRESGCSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300

Query  301  RRLAERPANLAFFLRALTDRRRARGCAER  329
            RRLAERPANLAFFLRALTDRRRARGCAER
Sbjct  301  RRLAERPANLAFFLRALTDRRRARGCAER  329


>gi|340626202|ref|YP_004744654.1| putative proline dehydrogenase [Mycobacterium canettii CIPT 140010059]
 gi|340004392|emb|CCC43535.1| putative proline dehydrogenase [Mycobacterium canettii CIPT 140010059]
Length=329

 Score =  645 bits (1665),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 327/329 (99%), Positives = 327/329 (99%), Gaps = 0/329 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAGWFAHTLRPAMLAAGRSDRLGRIVE SPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR
Sbjct  1    MAGWFAHTLRPAMLAAGRSDRLGRIVEHSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR
Sbjct  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR
Sbjct  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH
Sbjct  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DPVIIAAVPGITRESGRSQ DFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL
Sbjct  241  DPVIIAAVPGITRESGRSQDDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300

Query  301  RRLAERPANLAFFLRALTDRRRARGCAER  329
            RRLAERPANLAFFLRALTDRRRARGCAER
Sbjct  301  RRLAERPANLAFFLRALTDRRRARGCAER  329


>gi|289753257|ref|ZP_06512635.1| proline dehydrogenase [Mycobacterium tuberculosis EAS054]
 gi|289693844|gb|EFD61273.1| proline dehydrogenase [Mycobacterium tuberculosis EAS054]
Length=320

 Score =  579 bits (1493),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 294/294 (100%), Positives = 294/294 (100%), Gaps = 0/294 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR
Sbjct  27   MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  86

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR
Sbjct  87   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  146

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR
Sbjct  147  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  206

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH
Sbjct  207  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  266

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTR  294
            DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTR
Sbjct  267  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTR  320


>gi|183984224|ref|YP_001852515.1| proline dehydrogenase, PutA [Mycobacterium marinum M]
 gi|183177550|gb|ACC42660.1| proline dehydrogenase, PutA [Mycobacterium marinum M]
Length=319

 Score =  489 bits (1260),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 251/317 (80%), Positives = 276/317 (88%), Gaps = 0/317 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M   FAHT+RPAMLAA R+DRL R +E S +TR VVRRFVPG+T+D V+D+V ALRDSGR
Sbjct  1    MTRLFAHTVRPAMLAASRADRLRRTLEHSSVTRRVVRRFVPGETVDSVLDVVGALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             +SIDYLGENVTD DDAA  VRAYL LLDV+GRR D   DGVRPLEVS+KLSALGQAL+R
Sbjct  61   CVSIDYLGENVTDVDDAAETVRAYLNLLDVMGRRNDAGRDGVRPLEVSVKLSALGQALER  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNAR ICERAE+VG WVTVDAEDHTTT+STLSI+GDLRVDF WLGTVVQAYLR
Sbjct  121  DGQKIALDNARTICERAEQVGVWVTVDAEDHTTTESTLSIAGDLRVDFAWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTL DC ELA+VGARVRLCKGAYDEP SVAYRD  +VTDSYLRCL+VL AG GYPMVA+H
Sbjct  181  RTLDDCQELASVGARVRLCKGAYDEPESVAYRDRVEVTDSYLRCLQVLMAGSGYPMVASH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP IIA V G+  ESGRS  DFEYQMLYG+RD+EQ RL GAG+ VRVYVPFGT+WYGYF+
Sbjct  241  DPEIIATVAGMAHESGRSANDFEYQMLYGIRDEEQWRLVGAGSQVRVYVPFGTQWYGYFM  300

Query  301  RRLAERPANLAFFLRAL  317
            RRLAERPANL FFLRAL
Sbjct  301  RRLAERPANLGFFLRAL  317


>gi|118616697|ref|YP_905029.1| proline dehydrogenase, PutA [Mycobacterium ulcerans Agy99]
 gi|118568807|gb|ABL03558.1| proline dehydrogenase, PutA [Mycobacterium ulcerans Agy99]
Length=319

 Score =  486 bits (1252),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 249/317 (79%), Positives = 275/317 (87%), Gaps = 0/317 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M   FAHT+RPAMLAA R+DRL R +E S +TR VVRRFVPG+T+D V+D+V ALRDSGR
Sbjct  1    MTRLFAHTVRPAMLAASRADRLRRTLEHSSVTRRVVRRFVPGETVDSVLDVVGALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             ++IDYLGENVTD DDAA  VR YL LLDV+GRR D   DGVRPLEVS+KLSALGQAL+R
Sbjct  61   CVNIDYLGENVTDVDDAAQTVRVYLNLLDVMGRRNDAGRDGVRPLEVSVKLSALGQALER  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DGQKIALDNAR ICERAE+VG WVTVDAEDHTTT+STLSI+GDLRVDF WLGTVVQAYLR
Sbjct  121  DGQKIALDNARTICERAEQVGVWVTVDAEDHTTTESTLSIAGDLRVDFAWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTL DC ELA+VGARVRLCKGAYDEP SVAYRD  +VTDSYLRCL+VL AG GYPMVA+H
Sbjct  181  RTLDDCQELASVGARVRLCKGAYDEPESVAYRDRVEVTDSYLRCLQVLMAGSGYPMVASH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP IIA V G+  ESGRS  DFEYQMLYG+RD+EQ RL GAG+ VRVYVPFGT+WYGYF+
Sbjct  241  DPEIIATVAGMAHESGRSANDFEYQMLYGIRDEEQWRLVGAGSQVRVYVPFGTQWYGYFM  300

Query  301  RRLAERPANLAFFLRAL  317
            RRLAERPANL FFLRAL
Sbjct  301  RRLAERPANLGFFLRAL  317


>gi|240169049|ref|ZP_04747708.1| proline dehydrogenase, PutA [Mycobacterium kansasii ATCC 12478]
Length=319

 Score =  474 bits (1221),  Expect = 6e-132, Method: Compositional matrix adjust.
 Identities = 251/317 (80%), Positives = 273/317 (87%), Gaps = 0/317 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MA  FA TLRPA+LAAGRSDRL  +  RS +TR VVRRFVPG+TLD V+++V ALRDSGR
Sbjct  1    MARLFARTLRPALLAAGRSDRLRLMTGRSSVTRRVVRRFVPGETLDSVLEVVAALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            Y+SIDYLGENVTD D AAA VRAYL LLD LGRR D A DGVRPLEVS+KLSALGQALDR
Sbjct  61   YVSIDYLGENVTDTDGAAATVRAYLDLLDALGRRADTAFDGVRPLEVSVKLSALGQALDR  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG KIALDNAR ICERAE+VG WVTVDAEDHTTTDSTLSISGDLRVDF WLGTVVQAYLR
Sbjct  121  DGPKIALDNARTICERAEQVGVWVTVDAEDHTTTDSTLSISGDLRVDFGWLGTVVQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTLADC ELA+VGARVRLCKGAYDEP +VAYRD A +TDSYLRCL VL +G GYPMVA+H
Sbjct  181  RTLADCRELASVGARVRLCKGAYDEPTAVAYRDGAGITDSYLRCLHVLLSGSGYPMVASH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP II A  G+  E  R+  DFE+QMLYG+RDDEQRRL  AGN +RVYVPFG +WYGYF+
Sbjct  241  DPAIIGAAVGMAAEGRRTARDFEFQMLYGIRDDEQRRLATAGNQLRVYVPFGGQWYGYFM  300

Query  301  RRLAERPANLAFFLRAL  317
            RRLAERPANLAFFLRAL
Sbjct  301  RRLAERPANLAFFLRAL  317


>gi|108800989|ref|YP_641186.1| L-proline dehydrogenase [Mycobacterium sp. MCS]
 gi|119870130|ref|YP_940082.1| L-proline dehydrogenase [Mycobacterium sp. KMS]
 gi|126436826|ref|YP_001072517.1| L-proline dehydrogenase [Mycobacterium sp. JLS]
 gi|108771408|gb|ABG10130.1| L-proline dehydrogenase [Mycobacterium sp. MCS]
 gi|119696219|gb|ABL93292.1| L-proline dehydrogenase [Mycobacterium sp. KMS]
 gi|126236626|gb|ABO00027.1| L-proline dehydrogenase [Mycobacterium sp. JLS]
Length=318

 Score =  449 bits (1156),  Expect = 2e-124, Method: Compositional matrix adjust.
 Identities = 223/318 (71%), Positives = 256/318 (81%), Gaps = 1/318 (0%)

Query  3    GWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYL  62
            G F    RP +LAA RSD L    ER P+TR VV RFVPG+++++ +  VT LR+SGR +
Sbjct  2    GAFQRVARPVILAAARSDSLRHTAERLPVTRNVVHRFVPGESVEEAMYCVTGLRNSGRMV  61

Query  63   SIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDG  122
            S+DYLGE+VTD D A A V AY+ LLD LGRR D     VRPLEVSLKLSALGQAL RDG
Sbjct  62   SVDYLGEDVTDVDTANATVEAYVKLLDALGRR-DEPAGAVRPLEVSLKLSALGQALPRDG  120

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
            +KIAL+NA  IC  A+RVGAWVTVDAEDHTTTDSTLSI  +LR +F WLGTV+QAYLRRT
Sbjct  121  EKIALENAHTICTHAQRVGAWVTVDAEDHTTTDSTLSIVRELRSEFDWLGTVLQAYLRRT  180

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
             ADCAE AA GAR+RLCKGAYDEPASVA+RDA +VTD+YLRCL  L AGRGYPMVA+HDP
Sbjct  181  QADCAEFAASGARIRLCKGAYDEPASVAFRDADEVTDNYLRCLETLMAGRGYPMVASHDP  240

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
            V+I AVPG+    GR+ G +EYQMLYG+RD EQ+RL  AGN VRVYVPFGT+WYGYF+RR
Sbjct  241  VVIDAVPGLAAAQGRASGSYEYQMLYGIRDQEQQRLADAGNVVRVYVPFGTQWYGYFVRR  300

Query  303  LAERPANLAFFLRALTDR  320
            LAERPAN+AFFLRAL  R
Sbjct  301  LAERPANMAFFLRALAGR  318


>gi|296170087|ref|ZP_06851689.1| proline dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895254|gb|EFG74965.1| proline dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=320

 Score =  444 bits (1142),  Expect = 9e-123, Method: Compositional matrix adjust.
 Identities = 229/320 (72%), Positives = 253/320 (80%), Gaps = 2/320 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M   FA TLRPA++AA R   L R  E  P+TR VV RFVPG+T+D  +D V ALR SGR
Sbjct  1    MGRAFASTLRPAIIAASRHPGLRRAAEGLPVTRRVVHRFVPGETIDSALDSVAALRVSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            Y+S+DYLGE+VT ADDA AAVR YL L+  L R G+ A  GVRPLEVSLKLSALGQ+LDR
Sbjct  61   YVSLDYLGEDVTTADDADAAVRVYLDLIARLARFGEHA--GVRPLEVSLKLSALGQSLDR  118

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG+KIA DNA AICE A R G WVTVDAEDHTTTDSTL+I  DLR +F WLG  +QAYLR
Sbjct  119  DGEKIARDNAFAICEAARRAGVWVTVDAEDHTTTDSTLTIVRDLRAEFGWLGVALQAYLR  178

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RT  DC   AA GAR+RLCKGAYDEPASVAYRD   VTDSYLRCLRVL AG GYPMVA+H
Sbjct  179  RTPGDCEAFAAAGARIRLCKGAYDEPASVAYRDPDAVTDSYLRCLRVLMAGSGYPMVASH  238

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP II AVP + RE+GR   DFEYQMLYG+RDDEQRRL  +GN VRVYVPFGT+WYGYF+
Sbjct  239  DPAIIEAVPALAREAGRGAPDFEYQMLYGIRDDEQRRLAESGNRVRVYVPFGTQWYGYFM  298

Query  301  RRLAERPANLAFFLRALTDR  320
            RRLAERPANL FFLRAL  R
Sbjct  299  RRLAERPANLTFFLRALAQR  318


>gi|41408690|ref|NP_961526.1| hypothetical protein MAP2592c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397048|gb|AAS04909.1| hypothetical protein MAP_2592c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458673|gb|EGO37635.1| proline dehydrogenase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=320

 Score =  443 bits (1139),  Expect = 2e-122, Method: Compositional matrix adjust.
 Identities = 235/321 (74%), Positives = 261/321 (82%), Gaps = 2/321 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAG FAHTLRPA+LAAGR   L R  E  P+TR VV RF+ G+T+D  +D VTALRDSGR
Sbjct  1    MAGLFAHTLRPAILAAGRRPGLRRAAEALPVTRRVVHRFIAGETIDSALDSVTALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             +S+D+LGE+V+DADDA AAVR YL L+D LG  GD A   VRPLEVSLKLSALGQ+LDR
Sbjct  61   CVSVDHLGEDVSDADDADAAVRVYLELVDRLGCLGDGA--AVRPLEVSLKLSALGQSLDR  118

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG+KIA +NA AIC  A+R G WVTVDAEDHTTTDSTL I  DLR +F WLG  +QAYLR
Sbjct  119  DGEKIARENAWAICAAAQRAGVWVTVDAEDHTTTDSTLRIVRDLRREFDWLGVALQAYLR  178

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTL DC E AA GARVRLCKGAYDEPAS+AYRD A VTDSYLRCLRVL AG GYPMVA+H
Sbjct  179  RTLGDCEEFAAAGARVRLCKGAYDEPASLAYRDPAAVTDSYLRCLRVLMAGSGYPMVASH  238

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP II A P + RESGR  G+FEYQMLYG+RDDEQRRL  AG+ VRVYVPFGT+WYGYF+
Sbjct  239  DPAIIEAAPSLARESGRGTGEFEYQMLYGIRDDEQRRLAEAGHTVRVYVPFGTQWYGYFM  298

Query  301  RRLAERPANLAFFLRALTDRR  321
            RRLAERPANL FFLRAL  RR
Sbjct  299  RRLAERPANLTFFLRALAARR  319


>gi|342862075|ref|ZP_08718718.1| hypothetical protein MCOL_24411 [Mycobacterium colombiense CECT 
3035]
 gi|342130379|gb|EGT83694.1| hypothetical protein MCOL_24411 [Mycobacterium colombiense CECT 
3035]
Length=319

 Score =  439 bits (1129),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 233/321 (73%), Positives = 262/321 (82%), Gaps = 2/321 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAG FA TLRPA+LAAGR D + R  ER  LTR VV RFVPG+T++ V++ V ALRDSGR
Sbjct  1    MAGLFASTLRPAILAAGRRDGVRRTAERLTLTRKVVHRFVPGETIESVLNSVAALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             +S+DYLGE+V DADDA AAVR YL L++ LG  GD   D   P EVS+KLSALGQ+L+R
Sbjct  61   LVSVDYLGEDVADADDADAAVRTYLDLIEKLGGPGDF--DVAAPFEVSVKLSALGQSLER  118

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG KIA DNA +IC+ A R G WVTVDAE+HTTTDSTL I  DLR +FPWLG V+QAYLR
Sbjct  119  DGHKIARDNAWSICDAARRAGVWVTVDAENHTTTDSTLRIVRDLRTEFPWLGLVLQAYLR  178

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTL DC E AA GARVRLCKGAYDEPAS+AYR+  +VTDSYL CLRVL AG GYPMVATH
Sbjct  179  RTLDDCEEFAASGARVRLCKGAYDEPASLAYREPTEVTDSYLACLRVLMAGSGYPMVATH  238

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP IIAAVP ++RESGR   +FEYQMLYG+RDDEQRRL  AGN VRVYVPFGT+WYGYF+
Sbjct  239  DPEIIAAVPEMSRESGRRGREFEYQMLYGIRDDEQRRLAAAGNPVRVYVPFGTQWYGYFM  298

Query  301  RRLAERPANLAFFLRALTDRR  321
            RRLAERPANLAFFLRALT RR
Sbjct  299  RRLAERPANLAFFLRALTTRR  319


>gi|118464208|ref|YP_880577.1| proline dehydrogenase [Mycobacterium avium 104]
 gi|254774208|ref|ZP_05215724.1| proline dehydrogenase [Mycobacterium avium subsp. avium ATCC 
25291]
 gi|118165495|gb|ABK66392.1| proline dehydrogenase [Mycobacterium avium 104]
Length=320

 Score =  439 bits (1128),  Expect = 4e-121, Method: Compositional matrix adjust.
 Identities = 233/321 (73%), Positives = 259/321 (81%), Gaps = 2/321 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MAG FAHTLRPA+LAAGR   L R  E  P+TR VV RF+ G+T+D  +D VTALRDSGR
Sbjct  1    MAGLFAHTLRPAILAAGRRPGLRRAAEALPVTRRVVHRFIAGETIDSALDSVTALRDSGR  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             +S+D+LGE+V+DADDA AAVR YL L+D LG  GD A   VRPLEVSLKLSALGQ+LDR
Sbjct  61   CVSVDHLGEDVSDADDADAAVRVYLELVDRLGCLGDGA--AVRPLEVSLKLSALGQSLDR  118

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG+KIA +NA AIC  A+R G WVTVDAE HT TDSTL I  DLR +F WLG  +QAYLR
Sbjct  119  DGEKIARENAWAICAAAQRAGVWVTVDAEGHTATDSTLRIVRDLRREFDWLGVALQAYLR  178

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RTL DC E AA GARVRLCKGAYDEPAS+AYRD A VTDSYLRCLRVL AG GYPMVA+H
Sbjct  179  RTLGDCEEFAAAGARVRLCKGAYDEPASLAYRDPAAVTDSYLRCLRVLMAGSGYPMVASH  238

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP II A P + RESGR  G+FEYQMLYG+RDDEQRRL  AG+ VRVYVPFGT+WYGYF+
Sbjct  239  DPAIIEAAPSLARESGRGTGEFEYQMLYGIRDDEQRRLAEAGHTVRVYVPFGTQWYGYFM  298

Query  301  RRLAERPANLAFFLRALTDRR  321
            RRLAERPANL FFLRAL  RR
Sbjct  299  RRLAERPANLTFFLRALAARR  319


>gi|169628424|ref|YP_001702073.1| proline dehydrogenase [Mycobacterium abscessus ATCC 19977]
 gi|169240391|emb|CAM61419.1| Probable proline dehydrogenase [Mycobacterium abscessus]
Length=323

 Score =  430 bits (1106),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 208/317 (66%), Positives = 250/317 (79%), Gaps = 0/317 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            MA WF  T RPA+LAA RS RL    ER PLTR VVRRFVPG++ DDV+   T L DSGR
Sbjct  3    MAEWFGKTARPAILAASRSARLRHAAERMPLTRQVVRRFVPGESQDDVLGASTGLLDSGR  62

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
            ++SIDYLGE+ TD++ A   V AYL LLD L +R D    GVRPLE+SLKLSALGQAL R
Sbjct  63   FISIDYLGEDTTDSEQATRTVSAYLSLLDALAQRSDAVHTGVRPLEISLKLSALGQALPR  122

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG++IAL+NA+ +C +A++ G WVT DAEDHTTTDSTL+I  +LR DFP LGTV+QAYL+
Sbjct  123  DGERIALENAQLLCAKADQAGVWVTADAEDHTTTDSTLNIVRELRADFPGLGTVLQAYLK  182

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RT ADC +L+  G+R+RLCKGAYDEPA+VA+RD   V  +YLRCLRVL  G GYPMVA+H
Sbjct  183  RTYADCVDLSGKGSRIRLCKGAYDEPAAVAHRDPEDVDVAYLRCLRVLMEGDGYPMVASH  242

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP II A   + RE+GR  GD+EYQMLYG+R+ EQRRL G G+H+RVYVPFG +WYGYF+
Sbjct  243  DPAIIEAAGLMARETGRGPGDYEYQMLYGIREAEQRRLAGVGHHMRVYVPFGEQWYGYFV  302

Query  301  RRLAERPANLAFFLRAL  317
            RR+AERPAN+ FFLRAL
Sbjct  303  RRIAERPANMTFFLRAL  319


>gi|118467796|ref|YP_889365.1| proline dehydrogenase [Mycobacterium smegmatis str. MC2 155]
 gi|118169083|gb|ABK69979.1| proline dehydrogenase [Mycobacterium smegmatis str. MC2 155]
Length=317

 Score =  425 bits (1093),  Expect = 4e-117, Method: Compositional matrix adjust.
 Identities = 218/319 (69%), Positives = 244/319 (77%), Gaps = 3/319 (0%)

Query  3    GWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYL  62
            G F    RPA+LAA RS RL    ER P+TR VV RFV G+T+ + +D   ALR SGR +
Sbjct  2    GIFDRVARPAILAASRSQRLRATAERLPVTRRVVDRFVAGETVPEALDATAALRASGRLV  61

Query  63   SIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDG  122
            +IDYLGE+ T  +DA   V AYL LL+ L    D     VRPLEVSLKLSALGQAL RDG
Sbjct  62   TIDYLGEDTTSKEDADNTVAAYLALLEGLKSDSDA---KVRPLEVSLKLSALGQALPRDG  118

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
            +KIAL+NA  IC +A  + AWVTVDAEDHTTTDSTLSI  DLR +F WLGTV+QAYL+RT
Sbjct  119  EKIALENAHTICAKARDIEAWVTVDAEDHTTTDSTLSIVRDLRTEFDWLGTVLQAYLKRT  178

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
             ADCAE AA GAR+RLCKGAYDEPASVAYRD  +VTDSYL CLR+L AGRGYPMVA+HDP
Sbjct  179  RADCAEFAASGARIRLCKGAYDEPASVAYRDPDEVTDSYLTCLRILMAGRGYPMVASHDP  238

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
             IIAAVP + RE  R   DFEYQMLY +RD EQRRL   GNHVRVYVPFG  WYGYF+RR
Sbjct  239  EIIAAVPALAREYHRGVDDFEYQMLYNIRDGEQRRLADEGNHVRVYVPFGYEWYGYFVRR  298

Query  303  LAERPANLAFFLRALTDRR  321
            LAERPANL FFLRAL +RR
Sbjct  299  LAERPANLTFFLRALAERR  317


>gi|254822925|ref|ZP_05227926.1| hypothetical protein MintA_23559 [Mycobacterium intracellulare 
ATCC 13950]
Length=320

 Score =  422 bits (1086),  Expect = 3e-116, Method: Compositional matrix adjust.
 Identities = 222/320 (70%), Positives = 254/320 (80%), Gaps = 1/320 (0%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M G FA TLRPA+LAA R D + R  +R P+TR VVRRFVPG+T+   ++ V ALR SGR
Sbjct  2    MPGVFASTLRPAILAAARGDVVRRAAQRLPVTRRVVRRFVPGETIGSALNGVAALRSSGR  61

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR  120
             +S+DYLGE+V  ADDA AAV+ YL L+D LGR  D     VRPLEVS+KLSALGQ L R
Sbjct  62   LVSVDYLGEDVLSADDADAAVQVYLELIDGLGRL-DAGGGVVRPLEVSIKLSALGQTLGR  120

Query  121  DGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLR  180
            DG KIA +NA +IC+ A R G WVTVDAE+HTTT+STLSI+ DLR +FPWLG  +QAYLR
Sbjct  121  DGHKIARENAWSICDAAGRAGVWVTVDAENHTTTESTLSIARDLRAEFPWLGVALQAYLR  180

Query  181  RTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATH  240
            RT  DC E AA GARVRLCKGAYDEPASVAYR  A+VT++YL CLRVL  G GYPMVA+H
Sbjct  181  RTPGDCEEFAASGARVRLCKGAYDEPASVAYRGRAEVTEAYLACLRVLMTGTGYPMVASH  240

Query  241  DPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFL  300
            DP +I A   I RESGR  G+FEYQMLYG+RDDEQRRLTGAGNHVRVY+PFGT+WYGYF+
Sbjct  241  DPAVINAASAIARESGRGAGEFEYQMLYGIRDDEQRRLTGAGNHVRVYLPFGTQWYGYFM  300

Query  301  RRLAERPANLAFFLRALTDR  320
            RRLAERPANL FFLRAL  R
Sbjct  301  RRLAERPANLTFFLRALVGR  320


>gi|120405477|ref|YP_955306.1| proline dehydrogenase [Mycobacterium vanbaalenii PYR-1]
 gi|119958295|gb|ABM15300.1| L-proline dehydrogenase [Mycobacterium vanbaalenii PYR-1]
Length=320

 Score =  422 bits (1085),  Expect = 4e-116, Method: Compositional matrix adjust.
 Identities = 224/317 (71%), Positives = 255/317 (81%), Gaps = 1/317 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
            F    RP +LAA R + L R  ER  +TR VVRRFVPG++  DV+  V  LRDS R +SI
Sbjct  4    FDKIARPVILAASRREGLRRAAERMSVTRKVVRRFVPGESTADVITAVGDLRDSHRLVSI  63

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQK  124
            DYLGE+VTDAD A A V AYL LLD L  RG+ A   VRPLEVSLKLSALGQAL RDG+K
Sbjct  64   DYLGEDVTDADAADATVEAYLTLLDALAGRGETAA-AVRPLEVSLKLSALGQALPRDGEK  122

Query  125  IALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLA  184
            IAL+NARAICERA+R G WVTVDAEDHTTTDSTL+I  +LRVDF W+GTV+Q++L+R  A
Sbjct  123  IALENARAICERAQRAGVWVTVDAEDHTTTDSTLAIVRELRVDFDWVGTVLQSHLKRARA  182

Query  185  DCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVI  244
            DCAE AA GAR+RLCKGAY EPASVA+RD   VTDSYL+CLR+L AGRGYPMVA+HDP I
Sbjct  183  DCAEFAASGARIRLCKGAYAEPASVAFRDRDDVTDSYLQCLRILMAGRGYPMVASHDPEI  242

Query  245  IAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLA  304
            + AVP + RE GR   DFEYQMLYG+RD EQRRL  AGNH+RVYVPFGT+WYGYF+RRLA
Sbjct  243  LGAVPSMAREYGRGVDDFEYQMLYGIRDAEQRRLAEAGNHIRVYVPFGTQWYGYFVRRLA  302

Query  305  ERPANLAFFLRALTDRR  321
            ERPANL FFLRAL +RR
Sbjct  303  ERPANLTFFLRALAERR  319


>gi|325676444|ref|ZP_08156122.1| proline dehydrogenase [Rhodococcus equi ATCC 33707]
 gi|325552622|gb|EGD22306.1| proline dehydrogenase [Rhodococcus equi ATCC 33707]
Length=322

 Score =  370 bits (949),  Expect = 2e-100, Method: Compositional matrix adjust.
 Identities = 194/318 (62%), Positives = 231/318 (73%), Gaps = 0/318 (0%)

Query  3    GWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYL  62
            G  ++ LRPA+LAA RS R+   V R+P+T+ +VRRFV G++L D +   + L  +GR +
Sbjct  4    GVLSNPLRPAILAAARSSRVKSAVTRAPVTKSIVRRFVAGESLADAMAATSTLLVAGRSV  63

Query  63   SIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDG  122
            SID+LGE+  D + A   V AYL LL  L R    A  GVR LEVS+KLSALGQ L  DG
Sbjct  64   SIDHLGEDTLDVEQARNTVVAYLELLAELARLPQAAATGVRTLEVSMKLSALGQGLPGDG  123

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
             KIALD+AR IC  A   G WVTVDAEDHT TDSTL+I  +LR DFPWLGTV+QAYLRRT
Sbjct  124  DKIALDHARTICAAAHEHGVWVTVDAEDHTRTDSTLAIVRELRADFPWLGTVLQAYLRRT  183

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
              DC +LA  G+R+RLCKGAY EP SVAYR  A V  SY RCLRVL AG GYPMVATHDP
Sbjct  184  EGDCRDLAGAGSRIRLCKGAYREPESVAYRSRADVDASYRRCLRVLMAGDGYPMVATHDP  243

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
             +IA+V G+  E+GR   DFE+QML+G+RD EQ RL  AG  VRVYVP+G +WYGYF+RR
Sbjct  244  AMIASVDGLVTETGRGTDDFEHQMLFGIRDLEQARLVDAGRRVRVYVPYGAQWYGYFMRR  303

Query  303  LAERPANLAFFLRALTDR  320
            LAERP+NL FFLR+   R
Sbjct  304  LAERPSNLRFFLRSTLSR  321


>gi|111017371|ref|YP_700343.1| proline dehydrogenase [Rhodococcus jostii RHA1]
 gi|110816901|gb|ABG92185.1| proline dehydrogenase [Rhodococcus jostii RHA1]
Length=321

 Score =  368 bits (945),  Expect = 7e-100, Method: Compositional matrix adjust.
 Identities = 182/306 (60%), Positives = 221/306 (73%), Gaps = 2/306 (0%)

Query  18   RSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDA  77
            RS R+ R V R P+T+ +V RFV G+T D  V   T + DSGRY+SIDYLGE+ TD   A
Sbjct  16   RSPRMERTVSRIPVTKSLVDRFVAGETEDQAVAATTGILDSGRYISIDYLGEDTTDLGRA  75

Query  78   AAAVRAYLGLLDVLGRRGDIACDGVRP--LEVSLKLSALGQALDRDGQKIALDNARAICE  135
            +  V  YL LL  L +R      G RP  +EVSLKLSALGQ L RDG  +AL+NA  IC 
Sbjct  76   SGTVSHYLTLLSSLAQRAPATDSGGRPRSIEVSLKLSALGQFLPRDGHNVALENAHKICT  135

Query  136  RAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGAR  195
             AE  G WVTVDAEDHTTTDSTLSI G+LR DFP LGTV+QAYL+RT ADC +L+  G+R
Sbjct  136  AAEEAGVWVTVDAEDHTTTDSTLSIVGELREDFPTLGTVLQAYLKRTEADCRDLSGPGSR  195

Query  196  VRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRES  255
            +RLCKGAY EPASVAY+    V ++YLRCLR+L  G GYPMVA+HDP ++ A     + +
Sbjct  196  IRLCKGAYKEPASVAYQGKPAVDEAYLRCLRILMNGEGYPMVASHDPAMVDAALTQAKAT  255

Query  256  GRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFLR  315
            GR+  +FE QML+G+RD EQ RL     HVRVY+P+G +WYGYF+RRLAERPANLAFFLR
Sbjct  256  GRTTDEFEIQMLHGIRDTEQLRLVEQQQHVRVYLPYGEQWYGYFMRRLAERPANLAFFLR  315

Query  316  ALTDRR  321
            +LT  +
Sbjct  316  SLTSTK  321


>gi|312138853|ref|YP_004006189.1| proline dehydrogenase [Rhodococcus equi 103S]
 gi|311888192|emb|CBH47504.1| proline dehydrogenase [Rhodococcus equi 103S]
Length=322

 Score =  367 bits (942),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 193/318 (61%), Positives = 230/318 (73%), Gaps = 0/318 (0%)

Query  3    GWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYL  62
            G  ++ LRPA+LAA RS R+   V R+P+T+ +VRRFV G++L D +   + L  +GR +
Sbjct  4    GVLSNPLRPAILAAARSSRVKSAVTRAPVTKSIVRRFVAGESLADAMAATSTLLVAGRSV  63

Query  63   SIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDG  122
            SID+LGE+  D + A   V AYL LL  L R    A  GVR LEVS+KLSALGQ L  DG
Sbjct  64   SIDHLGEDTLDVEQARNTVVAYLELLAELARLPQAAATGVRTLEVSMKLSALGQGLPGDG  123

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
             KIALD+AR IC  A   G WVTVDAEDHT TDSTL+I  +LR DFPWLGTV+QAYLRRT
Sbjct  124  DKIALDHARTICAAAHEHGVWVTVDAEDHTRTDSTLAIVRELRADFPWLGTVLQAYLRRT  183

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
              DC +LA  G+R+RLCKGAY EP SVAYR  A V  SY RCLRVL AG GYPMVATHDP
Sbjct  184  EGDCRDLAGAGSRIRLCKGAYHEPESVAYRSRADVDASYRRCLRVLMAGDGYPMVATHDP  243

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
             +IA+V  +  E+GR   DFE+QML+G+RD EQ RL  AG  VRVYVP+G +WYGYF+RR
Sbjct  244  AMIASVDRLVTETGRGTDDFEHQMLFGIRDLEQARLVDAGRRVRVYVPYGAQWYGYFMRR  303

Query  303  LAERPANLAFFLRALTDR  320
            LAERP+NL FFLR+   R
Sbjct  304  LAERPSNLRFFLRSTLSR  321


>gi|336120703|ref|YP_004575489.1| proline dehydrogenase [Microlunatus phosphovorus NM-1]
 gi|334688501|dbj|BAK38086.1| proline dehydrogenase [Microlunatus phosphovorus NM-1]
Length=319

 Score =  366 bits (939),  Expect = 3e-99, Method: Compositional matrix adjust.
 Identities = 181/317 (58%), Positives = 227/317 (72%), Gaps = 1/317 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
              + LRPA+LAA RS+R+ R +  S LTR +V +FVPG + D  ++ V AL +SGR++S+
Sbjct  4    LTNPLRPALLAAARSERIERTITHSKLTRRLVTKFVPGASEDAAIEAVKALVNSGRFISV  63

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQK  124
            D+LGE+++DA +A   V AYL LLD     G     G +PLEVS+KLSALGQ+L   G++
Sbjct  64   DFLGEDISDASEADQTVAAYLSLLDAYAALGIEPVAGAQPLEVSIKLSALGQSLP-GGEE  122

Query  125  IALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLA  184
            +AL NAR IC  A+R G+WV VDAEDHTTTDSTL I  +LR +FP + TV+QAYL RT  
Sbjct  123  LALTNARIICAAADRAGSWVNVDAEDHTTTDSTLRIVRELRQEFPSVATVLQAYLHRTED  182

Query  185  DCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVI  244
            DC +LA  G+R+RLCKGAY EPA VAY+    VT SYLRCLR+L  G+GYPMVA+HDP I
Sbjct  183  DCRDLAGPGSRIRLCKGAYKEPAEVAYQSKEDVTASYLRCLRILMEGQGYPMVASHDPQI  242

Query  245  IAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLA  304
            I++       +GR    FE QMLYG+RD EQ +L   G HVR Y+PFG  WYGYF+RRLA
Sbjct  243  ISSAQAYAIAAGRDASKFEIQMLYGIRDAEQSQLINDGLHVRTYLPFGNDWYGYFMRRLA  302

Query  305  ERPANLAFFLRALTDRR  321
            ERPANL FFLRAL  R+
Sbjct  303  ERPANLVFFLRALVGRK  319


>gi|229489119|ref|ZP_04382985.1| proline dehydrogenase [Rhodococcus erythropolis SK121]
 gi|229324623|gb|EEN90378.1| proline dehydrogenase [Rhodococcus erythropolis SK121]
Length=321

 Score =  362 bits (929),  Expect = 5e-98, Method: Compositional matrix adjust.
 Identities = 183/313 (59%), Positives = 224/313 (72%), Gaps = 1/313 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
             ++ LRP +LAA RS RL + V    LTR +V RFV GD     +  V  +  SGR++++
Sbjct  6    LSNPLRPVLLAAARSSRLEKTVSGMTLTRKLVDRFVAGDAEPAAMSAVRDILTSGRFVTV  65

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQK  124
            DYLGE+ TD   A A V AYL LL       +IA      LEVSLKLSALGQ+L  DG+K
Sbjct  66   DYLGEDTTDPAQATATVDAYLSLLRSYATLSEIAGTQ-HSLEVSLKLSALGQSLPGDGEK  124

Query  125  IALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLA  184
            IAL NA  I   A+ VGAWVTVDAEDHTTTDSTLSI  +LR DFP LGTV+QAYL RT A
Sbjct  125  IALANAHRIVTAADEVGAWVTVDAEDHTTTDSTLSIVEELRRDFPTLGTVLQAYLHRTEA  184

Query  185  DCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVI  244
            DC   +  G+R+RLCKGAY EPA VA++ AA+V  SY+RCL+VL  G GYPMVA+HDP +
Sbjct  185  DCRHFSGSGSRIRLCKGAYKEPAGVAFQKAAEVDASYVRCLKVLMEGDGYPMVASHDPTM  244

Query  245  IAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLA  304
            I A  G+   + R+  DFE+QML+G+RD EQRRL   GNH+RVYVP+G++WYGYF+RRLA
Sbjct  245  IDAALGLATLTERTAADFEFQMLFGIRDGEQRRLVAEGNHLRVYVPYGSQWYGYFMRRLA  304

Query  305  ERPANLAFFLRAL  317
            ERPANL FF+R+L
Sbjct  305  ERPANLMFFMRSL  317


>gi|226308192|ref|YP_002768152.1| proline dehydrogenase [Rhodococcus erythropolis PR4]
 gi|226187309|dbj|BAH35413.1| putative proline dehydrogenase [Rhodococcus erythropolis PR4]
Length=321

 Score =  356 bits (914),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 182/313 (59%), Positives = 220/313 (71%), Gaps = 1/313 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
             ++ LRP +LAA RS RL + V    LTR +V RFV GD     V  V  +  SGR++++
Sbjct  6    LSNPLRPVLLAAARSSRLEKTVSGMTLTRKLVDRFVAGDAEPAAVSAVRDILTSGRFVTV  65

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQK  124
            DYLGE+ TD   A A V AYL LL       + A      LEVSLKLSALGQ+L  DG+K
Sbjct  66   DYLGEDTTDPAQATATVDAYLSLLRSYATLSE-AAGTQHTLEVSLKLSALGQSLPGDGEK  124

Query  125  IALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLA  184
            IAL NA  I   A+ VGAWVTVDAEDHTTTDSTLSI  +LR DFP LGTV+QAYL RT A
Sbjct  125  IALANAHRIVTAADEVGAWVTVDAEDHTTTDSTLSIVEELRRDFPTLGTVLQAYLHRTEA  184

Query  185  DCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVI  244
            DC   +  G+R+RLCKGAY EPA VA++   +V  SYLRCL+VL  G GYPMVA+HDP +
Sbjct  185  DCRHFSGSGSRIRLCKGAYKEPADVAFQKPGEVDASYLRCLKVLMEGDGYPMVASHDPTM  244

Query  245  IAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLA  304
            I A   +   + R+  DFE+QMLYG+RD EQRRL   GNH+RVYVP+G++WYGYF+RRLA
Sbjct  245  IDAALELATLTERTAEDFEFQMLYGIRDGEQRRLVAEGNHLRVYVPYGSQWYGYFMRRLA  304

Query  305  ERPANLAFFLRAL  317
            ERPANL FF+R+L
Sbjct  305  ERPANLMFFMRSL  317


>gi|226365423|ref|YP_002783206.1| proline dehydrogenase [Rhodococcus opacus B4]
 gi|226243913|dbj|BAH54261.1| putative proline dehydrogenase [Rhodococcus opacus B4]
Length=325

 Score =  355 bits (910),  Expect = 8e-96, Method: Compositional matrix adjust.
 Identities = 185/318 (59%), Positives = 226/318 (72%), Gaps = 2/318 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
             A+ LRPA+LAA RS R+ R V  +P+TR +V RFV G++ +  +  V  + DSGR +SI
Sbjct  7    LANPLRPAILAAARSSRVKRAVTGAPVTRKLVDRFVAGESRESALASVREILDSGRSVSI  66

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIA--CDGVRPLEVSLKLSALGQALDRDG  122
            D+LGE+  DA  A A V  YL L+  LG   + A    GVR LEVS+KLSALGQAL  DG
Sbjct  67   DFLGEDTRDAAGAQATVDEYLALVADLGALPEAADKGSGVRRLEVSMKLSALGQALAGDG  126

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
             +IA  NAR IC  AE  G WVTVDAEDHTTTDSTL+I  +LR DFPWLG VVQ+YLRRT
Sbjct  127  TRIATANARTICAAAEAAGVWVTVDAEDHTTTDSTLAIVRELRTDFPWLGAVVQSYLRRT  186

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
              DC  LA  G+RVRLCKGAY EP SVA++D A V  SYLRCL +L  G GYPMVA+HDP
Sbjct  187  ENDCRALAGPGSRVRLCKGAYREPESVAFKDRAAVDASYLRCLTILVEGDGYPMVASHDP  246

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
             +I AV  +   +GR+   +E+QML+G+RD EQRRL      VRVYVP+G++WY YF+RR
Sbjct  247  AVIDAVAPLVGRTGRAADAYEHQMLFGIRDLEQRRLANEDKQVRVYVPYGSQWYAYFMRR  306

Query  303  LAERPANLAFFLRALTDR  320
            LAERP+NL FFLR++  R
Sbjct  307  LAERPSNLRFFLRSVVTR  324


>gi|226362365|ref|YP_002780143.1| proline dehydrogenase [Rhodococcus opacus B4]
 gi|226240850|dbj|BAH51198.1| putative proline dehydrogenase [Rhodococcus opacus B4]
Length=323

 Score =  354 bits (908),  Expect = 1e-95, Method: Compositional matrix adjust.
 Identities = 179/303 (60%), Positives = 220/303 (73%), Gaps = 4/303 (1%)

Query  19   SDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDAA  78
            S R+ R V R P+TR +V RFV G+T D  +   T++ DSGRY+SID+LGE+ TD+  A 
Sbjct  17   SPRMERTVTRIPVTRSLVDRFVAGETEDQAIAATTSILDSGRYISIDHLGEDTTDSAQAD  76

Query  79   AAVRAYLGLLDVL----GRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALDNARAIC  134
            A V  YL LL  L     +    +   VR +EVSLKLSALGQ L RDG K+AL+NA  IC
Sbjct  77   ATVSHYLALLSDLAALSQKTASTSPASVRNVEVSLKLSALGQFLPRDGHKVALENAHKIC  136

Query  135  ERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGA  194
              AE  GAWVTVDAEDHTTTDSTLSI  +LR DFP LGTV+QAYL+RT ADC +L+  G+
Sbjct  137  TAAEEAGAWVTVDAEDHTTTDSTLSIVRELRKDFPSLGTVLQAYLKRTEADCRDLSGPGS  196

Query  195  RVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRE  254
            R+RLCKGAY EPASVA++    V ++YLRCLR+L  G+GYPMVA+HDP +I A     + 
Sbjct  197  RIRLCKGAYKEPASVAFQGKEAVDEAYLRCLRILMNGQGYPMVASHDPAMIEAALQQAKA  256

Query  255  SGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFL  314
             GR+  +FE QMLYG+RD EQ RL G   H+RVY+P+G +WYGYF+RRLAERPANL FFL
Sbjct  257  KGRTADEFEIQMLYGIRDAEQLRLIGEDKHLRVYLPYGEQWYGYFMRRLAERPANLTFFL  316

Query  315  RAL  317
            R+L
Sbjct  317  RSL  319


>gi|111022915|ref|YP_705887.1| proline dehydrogenase [Rhodococcus jostii RHA1]
 gi|110822445|gb|ABG97729.1| proline dehydrogenase [Rhodococcus jostii RHA1]
Length=325

 Score =  352 bits (902),  Expect = 6e-95, Method: Compositional matrix adjust.
 Identities = 183/318 (58%), Positives = 225/318 (71%), Gaps = 2/318 (0%)

Query  5    FAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSI  64
             A+ LRPA+LAA RS R+ R V  +P+TR +V RFV G+  +  +  V  + DSGR +SI
Sbjct  7    LANPLRPAILAAARSSRVKRAVTGAPVTRKLVDRFVAGENRESALAAVREILDSGRSVSI  66

Query  65   DYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIA--CDGVRPLEVSLKLSALGQALDRDG  122
            D+L E+  D   A A V  YL L+  LG   + A    GVR LEVS+KLSALGQAL  DG
Sbjct  67   DFLAEDTRDVAGAQATVDEYLALVADLGALPETADGTSGVRRLEVSMKLSALGQALAGDG  126

Query  123  QKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRT  182
            ++IA DNAR IC  AE  G WVTVDAEDHTTTDSTL+I  +LR D+PWLG VVQ+YLRRT
Sbjct  127  RRIATDNARTICAAAEAAGVWVTVDAEDHTTTDSTLAIVRELRNDYPWLGAVVQSYLRRT  186

Query  183  LADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDP  242
              DC  LA  G+RVRLCKGAY EP SVA++D A V  SYLRCL +L  G GYPMVA+HDP
Sbjct  187  EDDCRSLAGPGSRVRLCKGAYREPESVAFQDRAAVDASYLRCLGILMDGSGYPMVASHDP  246

Query  243  VIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRR  302
             +I AV  +   +GR+   +E+QML+G+RD EQRRL      VRVYVP+G++WY YF+RR
Sbjct  247  AVIDAVAPLVGRTGRAANAYEHQMLFGIRDVEQRRLANEDKQVRVYVPYGSQWYAYFMRR  306

Query  303  LAERPANLAFFLRALTDR  320
            LAERP+NL FFLR++  R
Sbjct  307  LAERPSNLRFFLRSVVTR  324


>gi|72160838|ref|YP_288495.1| L-proline dehydrogenase [Thermobifida fusca YX]
 gi|71914570|gb|AAZ54472.1| L-proline dehydrogenase [Thermobifida fusca YX]
Length=311

 Score =  338 bits (868),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 183/300 (61%), Positives = 216/300 (72%), Gaps = 8/300 (2%)

Query  19   SDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDAA  78
            S R    V RSPLTRGVVRRFV GDTLD  + ++  L  + R++++DYLGE++TDA+ A+
Sbjct  12   SPRCRDFVTRSPLTRGVVRRFVAGDTLDATLPVLRQL-TADRHVTVDYLGEDITDAEQAS  70

Query  79   AAVRAYLGLLDVLGRRGDIACDGVRP-LEVSLKLSALGQALDRDGQKIALDNARAICERA  137
              V AY  LL  LG  G      + P  EVS+KLSALG AL RDG ++ALD+AR IC  A
Sbjct  71   RTVDAYTHLLTALGEHG------LAPRAEVSVKLSALGLALPRDGAQLALDHARQICAAA  124

Query  138  ERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGARVR  197
            E VG  VTVD EDHTTTD+TL I   LRVDFP  G V+QAYLRRT ADC +LA  G+RVR
Sbjct  125  EAVGTTVTVDMEDHTTTDATLDIVHQLRVDFPRTGAVLQAYLRRTEADCRDLAVPGSRVR  184

Query  198  LCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRESGR  257
            LCKGAYDEPA+VAYRD A+V  SY+RCLR+L  G GYPMVATHDP ++     + R +GR
Sbjct  185  LCKGAYDEPATVAYRDRAEVDRSYVRCLRILMDGPGYPMVATHDPRLLRIAAFLARSAGR  244

Query  258  SQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFLRAL  317
            S   +EYQMLYGVR D Q  L   G  VRVYVP+G +WYGYF+RRLAERPAN AFF RAL
Sbjct  245  SADSYEYQMLYGVRTDLQAALADRGERVRVYVPYGEQWYGYFMRRLAERPANTAFFARAL  304


>gi|311898942|dbj|BAJ31350.1| putative proline dehydrogenase [Kitasatospora setae KM-6054]
Length=309

 Score =  338 bits (867),  Expect = 8e-91, Method: Compositional matrix adjust.
 Identities = 176/312 (57%), Positives = 217/312 (70%), Gaps = 5/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR A+LAA RS ++  +VE+ P T  +V RFV GD LD  VD    L  SGR +++D+LG
Sbjct  2    LRSALLAASRSPQVRTMVEKFPPTHAIVERFVAGDRLDQGVDATEKLVTSGRKVTLDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+  DAD AA    AY  LL  L   G +A D     EVS+KLSA+GQ L  DG+KIAL+
Sbjct  62   EDTKDADQAAGTALAYEHLLTALKETG-LAADA----EVSVKLSAVGQFLPVDGEKIALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NAR ICE A   G  VT+D EDHTTTDSTL+I+ +LR DFPWLG V+QAYLRRT ADC +
Sbjct  117  NARRICEAAAAAGTTVTLDMEDHTTTDSTLAIARELRADFPWLGVVLQAYLRRTEADCRD  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            L+  G+RVR+CKGAY EP SVA++    V  +Y+R L+VL AG GYPMVA+HDP +I   
Sbjct  177  LSHEGSRVRICKGAYKEPESVAFQGKRDVDLAYVRALKVLMAGEGYPMVASHDPNMIKIA  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +   + R    FEYQMLYG+R +EQ RL  AGN +RVY+P+G  WYGYF+RRLAERPA
Sbjct  237  GQLAEWNKRDVSSFEYQMLYGIRPEEQLRLAEAGNTMRVYLPYGQEWYGYFMRRLAERPA  296

Query  309  NLAFFLRALTDR  320
            NL FFLRA+  R
Sbjct  297  NLTFFLRAMATR  308


>gi|297559062|ref|YP_003678036.1| proline dehydrogenase [Nocardiopsis dassonvillei subsp. dassonvillei 
DSM 43111]
 gi|296843510|gb|ADH65530.1| Proline dehydrogenase [Nocardiopsis dassonvillei subsp. dassonvillei 
DSM 43111]
Length=308

 Score =  337 bits (865),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 177/313 (57%), Positives = 221/313 (71%), Gaps = 8/313 (2%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTAL-RDSGRYLSIDYL  67
            LR  +L A RS     IVER+P+TR +V+RFV G T D+ + +V  L RD  R++++D+L
Sbjct  2    LRKPLLLAARSQTCRTIVERTPVTRAMVKRFVAGSTQDEALPVVGELTRD--RHVTLDFL  59

Query  68   GENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIAL  127
            GE+ TD   A A V AY  LL  LG  G          EVS+KLSA+GQ L+ DG+KIAL
Sbjct  60   GEDTTDTAQAEATVTAYRDLLAALGEAG-----LAERAEVSVKLSAVGQFLNSDGEKIAL  114

Query  128  DNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCA  187
            DNAR I E A+ VG  +T+D EDHTTTDSTL I  +LR DFP++G V+QAYLRRT ADC 
Sbjct  115  DNARRIAEAAKAVGTTMTLDMEDHTTTDSTLGILRELRQDFPFVGAVLQAYLRRTEADCR  174

Query  188  ELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAA  247
            +L+  G+RVRLCKGAYDEP SVA+RD A+V  +Y+R LRVL  G GYPMVA+HDP +IA 
Sbjct  175  DLSGAGSRVRLCKGAYDEPESVAFRDKAEVDKAYVRALRVLMEGEGYPMVASHDPRMIAI  234

Query  248  VPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERP  307
               +   +GR + DFEYQMLYG+RD EQ RL   GN +RVYVP+G  WYGY++RRLAERP
Sbjct  235  AGSLAAANGRGEDDFEYQMLYGIRDAEQVRLAAEGNRMRVYVPYGDEWYGYYMRRLAERP  294

Query  308  ANLAFFLRALTDR  320
            AN+ F  R+L  R
Sbjct  295  ANVLFLARSLVTR  307


>gi|343927217|ref|ZP_08766695.1| putative proline dehydrogenase [Gordonia alkanivorans NBRC 16433]
 gi|343762834|dbj|GAA13621.1| putative proline dehydrogenase [Gordonia alkanivorans NBRC 16433]
Length=316

 Score =  336 bits (862),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 179/319 (57%), Positives = 220/319 (69%), Gaps = 7/319 (2%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M+  F   LRP + AA RS+R+ +  +R  +T  VVRRFVPG+TLDDV+  +    D G 
Sbjct  1    MSTLFDTLLRPTITAAARSERIKQTSQRWSVTEKVVRRFVPGETLDDVLAAIRGELDDGL  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRP--LEVSLKLSALGQAL  118
             ++ID+LGE+  D   A A V AY+ LL+ +   G      VRP  LEVS+KL+ALGQ L
Sbjct  61   AVTIDFLGEDTVDESQADATVAAYVSLLEAMPGLGP-----VRPGALEVSVKLTALGQRL  115

Query  119  DRDGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAY  178
               G KIA +NAR I   A   GA +T+DAEDH T D  L+I   LR DFP +GTV+QAY
Sbjct  116  PEHGAKIAEENARTIAAAAHHAGALITIDAEDHATVDERLAIVRSLRQDFPEVGTVLQAY  175

Query  179  LRRTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVA  238
            LRRT ADCAE AA GAR+RLCKGAY EP +VAY D  QV ++YLRCLR+L  G GYPMVA
Sbjct  176  LRRTEADCAEFAATGARIRLCKGAYAEPPAVAYPDRHQVDEAYLRCLRILMKGNGYPMVA  235

Query  239  THDPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGY  298
            +HDP +I     +  E  R+ G +E+QMLYG+R DEQRRL  +G  VRVY+P+GT WYGY
Sbjct  236  SHDPTMIEEASILAAEFDRAPGTWEHQMLYGIRVDEQRRLVESGARVRVYIPYGTEWYGY  295

Query  299  FLRRLAERPANLAFFLRAL  317
            F+RRLAERPANL FFLRAL
Sbjct  296  FVRRLAERPANLGFFLRAL  314


>gi|134098552|ref|YP_001104213.1| proline dehydrogenase [Saccharopolyspora erythraea NRRL 2338]
 gi|291003231|ref|ZP_06561204.1| proline dehydrogenase [Saccharopolyspora erythraea NRRL 2338]
 gi|133911175|emb|CAM01288.1| proline dehydrogenase [Saccharopolyspora erythraea NRRL 2338]
Length=309

 Score =  335 bits (859),  Expect = 6e-90, Method: Compositional matrix adjust.
 Identities = 174/313 (56%), Positives = 216/313 (70%), Gaps = 5/313 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +LAA RS  + ++VE +PLT  VV RFV G   +D V    +L D G ++++D+LG
Sbjct  2    LRTPLLAAARSTGVRKLVEANPLTSSVVDRFVAGTAPEDAVRATRSLSDQGMHVTLDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+  DA  A A VRAY  +L  L   G          EVS+KLSA+GQ L +DG+KIAL+
Sbjct  62   EDTLDAGQATATVRAYQRVLAELAEAGLTG-----RAEVSVKLSAVGQFLPKDGEKIALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NAR ICE A   G  VT+D EDHTTTDSTL I  DLRVDFPW+G V+Q+YL RT  DC +
Sbjct  117  NARLICEAAAAAGTTVTLDMEDHTTTDSTLGILADLRVDFPWVGAVLQSYLHRTEGDCRD  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LA  G+RVRLCKGAY EPASVA++   +V  SY+RCL+VL  G GYPMVATHDP +IA  
Sbjct  177  LATAGSRVRLCKGAYAEPASVAFQGKQEVDRSYVRCLKVLMNGAGYPMVATHDPRMIAIA  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +   + R+ G FEYQMLYG+R +EQRR+   G+ +RVYV +G  WYGYF+RRLAERPA
Sbjct  237  GDLAARARRAPGSFEYQMLYGIRTEEQRRIAAEGDRLRVYVAYGDEWYGYFMRRLAERPA  296

Query  309  NLAFFLRALTDRR  321
            NL FFLR+L   R
Sbjct  297  NLVFFLRSLLSNR  309


>gi|336120452|ref|YP_004575237.1| proline dehydrogenase [Microlunatus phosphovorus NM-1]
 gi|334688249|dbj|BAK37834.1| proline dehydrogenase [Microlunatus phosphovorus NM-1]
Length=311

 Score =  332 bits (850),  Expect = 6e-89, Method: Compositional matrix adjust.
 Identities = 173/315 (55%), Positives = 217/315 (69%), Gaps = 9/315 (2%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            +R A+L   RS  +   + R+PLTR VV R+V G+T DDV+ I   L D+   ++ID LG
Sbjct  4    VREALLKLSRSGAMKSTITRAPLTRDVVNRYVAGETTDDVLRITRTLADANLSITIDRLG  63

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRG--DIACDGVRPLEVSLKLSALGQALDRDGQKIA  126
            E+ T  + AA   RAYL LL +L   G  DIA       EVS+KLSA+GQ L RDG++IA
Sbjct  64   EDTTKVEQAAETTRAYLELLRLLDDAGLADIA-------EVSIKLSAVGQFLGRDGERIA  116

Query  127  LDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADC  186
             ++AR+ICE A  VG  VT+D EDHTTTDSTLS+   LR DFPWLGTV+QAYL R+ ADC
Sbjct  117  TEHARSICEAAGAVGTTVTIDMEDHTTTDSTLSVVRALRADFPWLGTVLQAYLHRSEADC  176

Query  187  AELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIA  246
             +LA  G+R+RLCKGAY EP SVAY + A++  +Y+RCLR+L AG GYPMVATHDP ++ 
Sbjct  177  RDLAYQGSRIRLCKGAYAEPESVAYAEPAEIDKAYVRCLRILMAGDGYPMVATHDPRLVE  236

Query  247  AVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAER  306
                +     RS+  FE QMLYG+R  EQ RL   G  +RVYVP+GT WYGY +RRLAE+
Sbjct  237  IALTLADRQHRSKDSFELQMLYGIRPAEQARLAALGRRMRVYVPYGTDWYGYLVRRLAEK  296

Query  307  PANLAFFLRALTDRR  321
            PANL FF R+L  RR
Sbjct  297  PANLRFFARSLVSRR  311


>gi|302525803|ref|ZP_07278145.1| proline dehydrogenase [Streptomyces sp. AA4]
 gi|302434698|gb|EFL06514.1| proline dehydrogenase [Streptomyces sp. AA4]
Length=309

 Score =  330 bits (847),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 178/312 (58%), Positives = 220/312 (71%), Gaps = 5/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +LAA RS R+  ++E  P+TR VVRRFV G    D V     L   GR ++ID+LG
Sbjct  2    LRAPLLAAARSQRMRALIEAVPVTRSVVRRFVSGSATADAVRAARELAADGRKITIDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+ TDA  A A V+AY  LL  L  +G       +  +VS+KLSA+GQ L  DG+ +AL+
Sbjct  62   EDTTDAAQATATVQAYEELLTALSEQGL-----AKGADVSVKLSAVGQFLPGDGEGVALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NAR IC  A+ VGA VT+D EDHTTTDSTL I  +LR ++PW+G V+QAYLRRT  DC E
Sbjct  117  NARKICAAADAVGATVTLDMEDHTTTDSTLGILRELRAEYPWVGAVLQAYLRRTEQDCRE  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            L+  G+RVRLCKGAY EP SVA++D A+V  SY+RCLRVL AG+GYPMVA+HDP IIA  
Sbjct  177  LSGPGSRVRLCKGAYAEPESVAFQDKAEVDKSYVRCLRVLMAGQGYPMVASHDPRIIAIA  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +  ++GR+  D EYQMLYG+R +EQ+RL   G  +RVYVP G  WYGYF+RRLAERPA
Sbjct  237  GKLAADAGRTSSDHEYQMLYGIRPEEQKRLASEGETMRVYVPCGDEWYGYFMRRLAERPA  296

Query  309  NLAFFLRALTDR  320
            NLAFFLR L  R
Sbjct  297  NLAFFLRGLVTR  308


>gi|54024324|ref|YP_118566.1| putative proline dehydrogenase [Nocardia farcinica IFM 10152]
 gi|54015832|dbj|BAD57202.1| putative proline dehydrogenase [Nocardia farcinica IFM 10152]
Length=323

 Score =  330 bits (847),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 177/293 (61%), Positives = 212/293 (73%), Gaps = 1/293 (0%)

Query  32   TRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDAAAAVRAYLGLLDVL  91
            TR +V RFV G T  D +  V AL  SGR++++D+LGE+ TD   A   V  Y  LL  L
Sbjct  31   TRALVDRFVAGTTEADALGTVEALLASGRWITVDHLGEHTTDPARARDTVAHYRRLLAAL  90

Query  92   GRRGDIACDG-VRPLEVSLKLSALGQALDRDGQKIALDNARAICERAERVGAWVTVDAED  150
                     G VRPLEVS+KLSALGQAL  DG  IALD+AR IC  A   G  VTVDAED
Sbjct  91   AELPAAGAPGTVRPLEVSVKLSALGQALPGDGAAIALDHAREICTAASAAGIGVTVDAED  150

Query  151  HTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGARVRLCKGAYDEPASVA  210
            HTTTD+TL++  +LR DFP +GTV+QAYLRRT  DC E A  G+R+RLCKGAY EPASVA
Sbjct  151  HTTTDATLAVVRELRADFPGVGTVLQAYLRRTEGDCREFAGPGSRIRLCKGAYREPASVA  210

Query  211  YRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRESGRSQGDFEYQMLYGV  270
            ++ AA+V DSY RCLR+L +GRGYPMVA+HDP ++A    +  E+GR   DFEYQML+G+
Sbjct  211  FQRAAEVDDSYRRCLRILMSGRGYPMVASHDPAMLAEADRLAAETGRGPDDFEYQMLFGI  270

Query  271  RDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFLRALTDRRRA  323
            RD EQRRL  AG+ +RVYVP+G +WYGYF+RRLAERPANLAFFLRA   R RA
Sbjct  271  RDAEQRRLADAGHRMRVYVPYGDQWYGYFMRRLAERPANLAFFLRAAASRDRA  323


>gi|262201272|ref|YP_003272480.1| proline dehydrogenase [Gordonia bronchialis DSM 43247]
 gi|262084619|gb|ACY20587.1| Proline dehydrogenase [Gordonia bronchialis DSM 43247]
Length=317

 Score =  328 bits (841),  Expect = 8e-88, Method: Compositional matrix adjust.
 Identities = 182/323 (57%), Positives = 217/323 (68%), Gaps = 8/323 (2%)

Query  1    MAGWFAHTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGR  60
            M+  F   LRP ++AA RSDR+    ER  +TR VVRRFVPGD LDDVV  +    D+G 
Sbjct  1    MSTIFDSLLRPTIIAAARSDRIKHTSERLTVTRNVVRRFVPGDDLDDVVRAIWRQLDNGT  60

Query  61   YLSIDYLGENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRP--LEVSLKLSALGQAL  118
             +SID+LGE+ T    A   V AYL LL+ +      A     P  LEVS+KL+ALGQ+L
Sbjct  61   SVSIDFLGEDTTTEAQADGTVEAYLALLEAMS-----AIHAALPGQLEVSVKLTALGQSL  115

Query  119  DRDGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAY  178
               G KIA  NAR I   A   G  VTVDAEDHTT D  L I   LR DFP +GTV+QAY
Sbjct  116  PEHGPKIAEANARRIVTAAYAAGVLVTVDAEDHTTVDQRLDIVRSLRGDFPEVGTVLQAY  175

Query  179  LRRTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVA  238
            LRRT  DC E AA GAR+RLCKGAY EP SVA+ D   + ++YLRCLR+L  G GYPMVA
Sbjct  176  LRRTEDDCTEFAAAGARIRLCKGAYAEPPSVAFPDRRLIDEAYLRCLRILMKGNGYPMVA  235

Query  239  THDPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGY  298
            +HDPVII A   +  E GR   ++E+QMLYG+R DEQRRL   G HVRVY+P+G +WYGY
Sbjct  236  SHDPVIIEAAALLAAEVGREPDNWEHQMLYGIRTDEQRRLAARG-HVRVYIPYGQQWYGY  294

Query  299  FLRRLAERPANLAFFLRALTDRR  321
             +RRLAE+PANL FFLRAL  +R
Sbjct  295  LVRRLAEKPANLTFFLRALGRQR  317


>gi|317509148|ref|ZP_07966773.1| proline dehydrogenase [Segniliparus rugosus ATCC BAA-974]
 gi|316252554|gb|EFV11999.1| proline dehydrogenase [Segniliparus rugosus ATCC BAA-974]
Length=316

 Score =  325 bits (832),  Expect = 8e-87, Method: Compositional matrix adjust.
 Identities = 177/320 (56%), Positives = 219/320 (69%), Gaps = 11/320 (3%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            +RPA+LAA +S RL  + +R   TR VV RFV GDTL+D +  V  L  + R++S+DYLG
Sbjct  1    MRPALLAASKSQRLEALSQRFAFTRAVVSRFVAGDTLEDALPAVAQLLAT-RFVSVDYLG  59

Query  69   ENVTDADDAAAAVRAYLGLL-------DVLGRRGDIACDGVRPLEVSLKLSALGQALDRD  121
            ENV D + A A VRAYL LL       D L  RG +  DG   +E S+KLSA GQ+L   
Sbjct  60   ENVRDREQAQATVRAYLALLDGLGGLRDELAARGRVLADGA--VEASIKLSAFGQSLP-G  116

Query  122  GQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRR  181
            GQ IAL  A+ +C +A+ VGA VTVD EDHTTTD TL++  +LR DFP  G V+Q+YLRR
Sbjct  117  GQSIALAGAQEVCAKADEVGALVTVDMEDHTTTDGTLALVRELRSDFPQTGAVLQSYLRR  176

Query  182  TLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHD  241
            T ADC +LA  G+R+RLCKGAY EP SVAY+D  +V  +Y RCL +L  G GYPMVA+HD
Sbjct  177  TEADCRDLAVPGSRIRLCKGAYQEPDSVAYQDKREVDSAYRRCLAILFEGGGYPMVASHD  236

Query  242  PVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLR  301
            P +IA    +   + R    +EYQMLYGVR DEQ RL  +   VR+YVP+G +WYGYF R
Sbjct  237  PAMIAEAGRLASATRRVAASYEYQMLYGVRPDEQARLAASRARVRIYVPYGGQWYGYFTR  296

Query  302  RLAERPANLAFFLRALTDRR  321
            RLAERPAN+ FFLRAL  RR
Sbjct  297  RLAERPANVGFFLRALLGRR  316


>gi|256375223|ref|YP_003098883.1| proline dehydrogenase [Actinosynnema mirum DSM 43827]
 gi|255919526|gb|ACU35037.1| Proline dehydrogenase [Actinosynnema mirum DSM 43827]
Length=307

 Score =  324 bits (830),  Expect = 1e-86, Method: Compositional matrix adjust.
 Identities = 171/293 (59%), Positives = 211/293 (73%), Gaps = 7/293 (2%)

Query  25   IVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDAAAAVRAY  84
            +VE +PLTR VVRRFV G+T  D +     L   GR +++D+LGE+  DA  AA  VRAY
Sbjct  18   LVEGTPLTRPVVRRFVAGETTADAIAATGELLADGRLVTLDHLGEDTKDAAQAAGTVRAY  77

Query  85   LGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALDNARAICERAERVGAWV  144
            + LL    +R D A    R  EVS+KLSA+GQ L  DG+KIAL+NARAIC  A   G  V
Sbjct  78   VELL----KRLDDAGYADRA-EVSVKLSAVGQFLPVDGEKIALENARAICSAAADAGTTV  132

Query  145  TVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGARVRLCKGAYD  204
            T+D EDH+TTDSTLS+  +LRVDFPW+G V+QAYLRRT  DC +LA  G+RVRLCKGAY 
Sbjct  133  TLDMEDHSTTDSTLSVLRELRVDFPWVGAVLQAYLRRTEQDCRDLAVAGSRVRLCKGAYQ  192

Query  205  EPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRESGRSQGDFEY  264
            EP SVAY+  A+V  +Y+RCL+VL AG GYPMVA+HDP +IA    +   +GR    +E+
Sbjct  193  EPESVAYQSKAEVDLAYVRCLKVLMAGEGYPMVASHDPRLIAIAGELA--AGRGADGYEH  250

Query  265  QMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFLRAL  317
            QMLYG+R DEQ RL   G  +RVYVP+G  WYGYF+RRLAERPAN+AFFLR+L
Sbjct  251  QMLYGIRPDEQVRLAAEGQRMRVYVPYGGEWYGYFMRRLAERPANVAFFLRSL  303


>gi|84494994|ref|ZP_00994113.1| proline dehydrogenase [Janibacter sp. HTCC2649]
 gi|84384487|gb|EAQ00367.1| proline dehydrogenase [Janibacter sp. HTCC2649]
Length=316

 Score =  324 bits (830),  Expect = 2e-86, Method: Compositional matrix adjust.
 Identities = 164/295 (56%), Positives = 206/295 (70%), Gaps = 3/295 (1%)

Query  26   VERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDAAAAVRAYL  85
            +E++P++R VV+R+VPG  +   V     LR + R ++IDYLGE+  DA  AA  V  Y+
Sbjct  24   IEKAPVSRSVVQRYVPGTDVAHAVSAAAELRATNRMVTIDYLGEDTLDAGQAAHTVDTYV  83

Query  86   GLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALDNARAICERAERVGAWVT  145
            GLL  L  R D+   G    EVS+KLSA+GQAL +DG++IALDNAR ICE A+     VT
Sbjct  84   GLLRALKAR-DLTQFGA--AEVSVKLSAVGQALPQDGEQIALDNARRICEIAKDADTTVT  140

Query  146  VDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAVGARVRLCKGAYDE  205
            +D EDHTTTDSTL I  +LR DFP  G VVQ+YL RT ADC +LA  G+RVRLCKGAY E
Sbjct  141  LDMEDHTTTDSTLGILAELRKDFPSTGAVVQSYLHRTEADCRDLATAGSRVRLCKGAYKE  200

Query  206  PASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGITRESGRSQGDFEYQ  265
            PASVAY+DA  V  SY+RCL+VL  G GYPM+A+HDP +I     +    GR    +E+Q
Sbjct  201  PASVAYQDAGDVDLSYVRCLKVLMEGDGYPMIASHDPRLIDIARALASRHGREPDSYEFQ  260

Query  266  MLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAFFLRALTDR  320
            MLYG+R DEQ R+   G+ +RVYVPFG  WYGY +RR+AERPANL FFLR+L  +
Sbjct  261  MLYGIRPDEQTRIADRGHQMRVYVPFGEEWYGYLMRRMAERPANLQFFLRSLVSK  315


>gi|119714744|ref|YP_921709.1| L-proline dehydrogenase [Nocardioides sp. JS614]
 gi|119535405|gb|ABL80022.1| L-proline dehydrogenase [Nocardioides sp. JS614]
Length=316

 Score =  320 bits (820),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 162/309 (53%), Positives = 210/309 (68%), Gaps = 10/309 (3%)

Query  18   RSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLGENVTDADDA  77
            RS  + ++V   P++ G+VR +VPG+T +  V     L D G  +++DYLGE+ TDA+ A
Sbjct  13   RSSLVKKVVSGMPVSAGIVRSYVPGETTESAVGATAELVDGGLRVTLDYLGEDTTDAEQA  72

Query  78   AAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDR-----DGQKIALDNARA  132
             A V AYL +L  L  RG       R  EVS+KLSA+GQ L        G+KIAL+NAR 
Sbjct  73   DATVAAYLDVLQELSARGL-----TRNAEVSVKLSAIGQFLPDAVGFGGGEKIALENART  127

Query  133  ICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAELAAV  192
            IC  A   G  VT+D EDHTTTDSTLSI  +LR DFP  G V+QA L RT +DC  LA  
Sbjct  128  ICRAARNAGTAVTLDMEDHTTTDSTLSILRELRKDFPETGAVLQAALHRTESDCRALAYE  187

Query  193  GARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAVPGIT  252
            G+RVRLCKGAY EP SVA++D  +++ SY+RCL+VL AG GYPM+ATHDP +I     + 
Sbjct  188  GSRVRLCKGAYLEPESVAFQDRLEISKSYVRCLKVLLAGEGYPMIATHDPRMIEIASSLA  247

Query  253  RESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPANLAF  312
               GR+ G +EYQMLYG+R +EQRRL  +G  +RVYVP+GT WYGY +RRLAERP NL+F
Sbjct  248  SRYGRAAGTYEYQMLYGIRPEEQRRLVASGETMRVYVPYGTEWYGYLMRRLAERPQNLSF  307

Query  313  FLRALTDRR  321
            F+++L  ++
Sbjct  308  FVKSLVSKK  316


>gi|330470601|ref|YP_004408344.1| proline dehydrogenase [Verrucosispora maris AB-18-032]
 gi|328813572|gb|AEB47744.1| proline dehydrogenase [Verrucosispora maris AB-18-032]
Length=309

 Score =  318 bits (816),  Expect = 5e-85, Method: Compositional matrix adjust.
 Identities = 177/314 (57%), Positives = 208/314 (67%), Gaps = 9/314 (2%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +L    S R  R +E +PLTR VV RFV G+ +   V     L D+G   ++DYLG
Sbjct  2    LRQVILKTAASRRARRAIEATPLTRAVVDRFVAGENVPSAVRASEGLNDAGCLATLDYLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+ TD   A      Y+ LLD L    D    G+   EVS+KLSALGQAL R+G+ +ALD
Sbjct  62   EDTTDRAHAEHVTGQYVALLDGLA---DAGLTGM--AEVSIKLSALGQALPREGEAVALD  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NA  IC  A R G  VTVD EDHTTTDSTL I   LR DFP  G V+QAYLRR+  DC +
Sbjct  117  NASRICAAAARAGTTVTVDMEDHTTTDSTLGIVAQLRRDFPETGAVIQAYLRRSEGDCRD  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LA  G+RVRLCKGAY EPASVAY+  A+VT +YLRC  +L AG GYPM+ATHDP +I  V
Sbjct  177  LATAGSRVRLCKGAYREPASVAYQARAEVTQAYLRCAEILLAGPGYPMLATHDPELI--V  234

Query  249  PGITRESGRSQG--DFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAER  306
             G    +GR  G   +E+QMLYG+R  EQRRL  AG+ VRVYVPFG  WYGY +RRLAER
Sbjct  235  AGTRLAAGRPGGVTGYEFQMLYGIRPTEQRRLAEAGHQVRVYVPFGEEWYGYLMRRLAER  294

Query  307  PANLAFFLRALTDR  320
            PANL FF RALT R
Sbjct  295  PANLMFFFRALTSR  308


>gi|300784568|ref|YP_003764859.1| proline dehydrogenase [Amycolatopsis mediterranei U32]
 gi|299794082|gb|ADJ44457.1| proline dehydrogenase [Amycolatopsis mediterranei U32]
Length=309

 Score =  318 bits (816),  Expect = 6e-85, Method: Compositional matrix adjust.
 Identities = 175/312 (57%), Positives = 216/312 (70%), Gaps = 5/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +LAA RS  + R+VE  P TR VVRRFV G    D V +   L   GR +++D+LG
Sbjct  2    LRAPLLAAARSKGIRRLVEAVPATRSVVRRFVAGSETADAVRVARELAADGRRITLDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+ TDA  AAA V AY  +L  L   G    +G    +VS+KLSA+GQ L  DG+ +AL+
Sbjct  62   EDTTDATQAAATVAAYEAVLTALAAEG--LAEGA---DVSVKLSAVGQFLPSDGEDVALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NAR IC  AE VGA VT+D EDHTTTDSTL I  +LR ++PW+G V+QAYLRRT  DC E
Sbjct  117  NARKICAAAEAVGATVTLDMEDHTTTDSTLGILRELRGEYPWVGAVLQAYLRRTEQDCRE  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LA  G+RVRLCKGAY EP SVA+ + ++V  SY+RCLRVL AG GYPMVA+HDP +I   
Sbjct  177  LAGPGSRVRLCKGAYAEPESVAFPEKSEVDKSYVRCLRVLMAGEGYPMVASHDPRMIEIA  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +  E GR+  D E+QMLYG+R +EQ R+  +G  +RVYVP+G  WYGYF+RRLAERPA
Sbjct  237  AALAEEHGRTDDDHEFQMLYGIRPEEQARIAASGARMRVYVPYGDEWYGYFMRRLAERPA  296

Query  309  NLAFFLRALTDR  320
            NL FFLR L  R
Sbjct  297  NLGFFLRGLATR  308


>gi|296395172|ref|YP_003660056.1| proline dehydrogenase [Segniliparus rotundus DSM 44985]
 gi|296182319|gb|ADG99225.1| Proline dehydrogenase [Segniliparus rotundus DSM 44985]
Length=329

 Score =  317 bits (812),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 180/321 (57%), Positives = 217/321 (68%), Gaps = 11/321 (3%)

Query  7    HTLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDY  66
            H  RP +LAA +S RL  + +R   TR VV RFV G  LDD + +V  L  S R++S+D+
Sbjct  13   HPARPVLLAASKSQRLESLSQRFAFTRAVVSRFVAGYELDDALRVVADLLGS-RFVSVDH  71

Query  67   LGENVTDADDAAAAVRAYLGLLDVLGR-------RGDIACDGVRPLEVSLKLSALGQALD  119
            LGENV D   A AAV+A+  LLD LGR       RG    DG   LE S+KLSA GQ L 
Sbjct  72   LGENVRDRAQAEAAVQAHRDLLDGLGRVRDELAARGQPLPDGA--LEASIKLSAFGQLLP  129

Query  120  RDGQKIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYL  179
             DGQ +AL  A+A+C +A+ VGA VTVD EDHTTT++TLS+   LR DFPW G V+Q+YL
Sbjct  130  -DGQALALAGAQALCAKADEVGALVTVDMEDHTTTEATLSVVRALRSDFPWTGAVLQSYL  188

Query  180  RRTLADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVAT  239
            +RT ADC + A  G+R+RLCKGAY EP SVAY+D  QV  SY RCL VL  G GYPMVA+
Sbjct  189  KRTEADCRDFAGPGSRIRLCKGAYQEPKSVAYQDKEQVDSSYKRCLAVLFEGDGYPMVAS  248

Query  240  HDPVIIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYF  299
            HDP +IA    +   + R    +E+QMLYGVR DEQ RL  +   VR YVP+G RWYGYF
Sbjct  249  HDPAMIAEATRLAAATSRVASSYEHQMLYGVRADEQARLAASRVRVRTYVPYGGRWYGYF  308

Query  300  LRRLAERPANLAFFLRALTDR  320
            +RRLAERPANL FFLRAL  R
Sbjct  309  VRRLAERPANLGFFLRALAGR  329


>gi|256397454|ref|YP_003119018.1| Proline dehydrogenase [Catenulispora acidiphila DSM 44928]
 gi|256363680|gb|ACU77177.1| Proline dehydrogenase [Catenulispora acidiphila DSM 44928]
Length=309

 Score =  314 bits (804),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 169/312 (55%), Positives = 213/312 (69%), Gaps = 5/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +LAA  SDR   +VERSP +R VV+R+V G   DD V +  AL + G   ++D+LG
Sbjct  2    LRRTLLAAAGSDRTRALVERSPGSRQVVKRYVAGPATDDAVAVADALIEDGLLATLDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+ TDA+ A     AYL LL+ L   G          EVS+KLSA+GQ+L  DG+KIAL+
Sbjct  62   EDTTDANQAILVKEAYLLLLERLAAAGLTP-----HAEVSVKLSAIGQSLSSDGEKIALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            +A AICE A+R G  VT D EDH+TTDSTL I  +LR D+PW G V+QAYLRRT ADC +
Sbjct  117  HAHAICEGAQRAGTTVTFDMEDHSTTDSTLKIVAELRRDYPWAGIVLQAYLRRTEADCKD  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
             A  G+RVRLCKGAY EP SVAY+    V  S++RC+R L AG GYPM+ATHDP +I   
Sbjct  177  FATPGSRVRLCKGAYREPESVAYQTTQDVDLSFVRCMRTLMAGEGYPMLATHDPRLIEIG  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +   +GR  G +E+QML+GVR  EQ+RL  AG  +RVYVP+G+ WYGY +RRLAERPA
Sbjct  237  GALAVRNGRGIGSYEFQMLFGVRPHEQKRLASAGERMRVYVPYGSEWYGYLMRRLAERPA  296

Query  309  NLAFFLRALTDR  320
            NL FF R+L  +
Sbjct  297  NLGFFARSLLSK  308


>gi|284034267|ref|YP_003384198.1| proline dehydrogenase [Kribbella flavida DSM 17836]
 gi|283813560|gb|ADB35399.1| Proline dehydrogenase [Kribbella flavida DSM 17836]
Length=309

 Score =  311 bits (798),  Expect = 7e-83, Method: Compositional matrix adjust.
 Identities = 160/313 (52%), Positives = 207/313 (67%), Gaps = 5/313 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            LR  +L   RS ++   V   P++ G+V RFV G+T  + V     L  +G  +++D+LG
Sbjct  2    LRRVLLGVSRSPQIKNAVSSLPVSSGIVARFVAGETAPEAVLATEKLVSNGLNVTLDHLG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E+ TD   A+A   AY+ LL  L      A    +  EVS+KLSA+GQAL  DG+KIAL+
Sbjct  62   EDTTDLATASATADAYVELLKQLA-----AAGLTQHAEVSVKLSAVGQALPGDGEKIALE  116

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            NAR IC  A   G  VT+D EDHTTTDSTL I  +LR DFP  G V+QAYLRRT ADC +
Sbjct  117  NARTICLAARNAGTTVTLDMEDHTTTDSTLGILHELRKDFPETGAVLQAYLRRTEADCVD  176

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LA  G+RVRLCKGAY EP SVA+++   V  +Y+R ++VL  G GYPM+A+HDP +IA  
Sbjct  177  LAYAGSRVRLCKGAYKEPESVAFQNKQAVDKAYVRAMKVLMNGDGYPMIASHDPRLIAIA  236

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +   + RS+  FEYQMLYG+R +EQ RL   GN VRVY+P+G  WYGY +RRLAERPA
Sbjct  237  GSLAARANRSRDSFEYQMLYGIRPEEQLRLAREGNTVRVYIPYGADWYGYLVRRLAERPA  296

Query  309  NLAFFLRALTDRR  321
            NL FF R+L  ++
Sbjct  297  NLQFFARSLISKK  309


>gi|329936823|ref|ZP_08286502.1| proline dehydrogenase [Streptomyces griseoaurantiacus M045]
 gi|329303748|gb|EGG47632.1| proline dehydrogenase [Streptomyces griseoaurantiacus M045]
Length=308

 Score =  310 bits (793),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 162/317 (52%), Positives = 213/317 (68%), Gaps = 16/317 (5%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSDRL R+V  +P+TR VV RF+PG+ +DD+V +V  L D G  L++D +G
Sbjct  2    LGPVILAASRSDRLRRLVSAAPVTRPVVDRFIPGENVDDIVPVVRELTDKGLELTMDVVG  61

Query  69   ENVTDADDAAAAVRAYLGLLD-----VLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQ  123
            E++T  + AAAA  AYL L+D      LGRR           E+S+KLS  GQAL   G 
Sbjct  62   EDITTPEQAAAARDAYLELIDRLKPMELGRRA----------EMSVKLSMFGQALP-GGH  110

Query  124  KIALDNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTL  183
            ++AL N R + E A+ +G  VT+DAEDHTT DS  ++  +LR DFP  G V+QAYL RT 
Sbjct  111  ELALANVRPVVEAADAIGTTVTLDAEDHTTLDSMFAVHEELRRDFPRTGCVIQAYLFRTE  170

Query  184  ADCAELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPV  243
            AD   LAA G+RVRL KGAY EPASVAY+D  ++  +Y+R LR L  G GYPMV +HDP 
Sbjct  171  ADARRLAASGSRVRLVKGAYKEPASVAYQDRHEIDKAYVRVLRTLMEGEGYPMVGSHDPR  230

Query  244  IIAAVPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRL  303
            ++A    + R +GR Q ++E+QMLYG+R +E  RL   G+ +RVY  +GT WYGYF+RRL
Sbjct  231  LVAIAQELARRAGRKQDEYEFQMLYGIRSEEHLRLAAEGHRMRVYTAYGTDWYGYFMRRL  290

Query  304  AERPANLAFFLRALTDR  320
            AE+PANL FF R++  R
Sbjct  291  AEKPANLRFFARSVVGR  307


>gi|297202562|ref|ZP_06919959.1| proline dehydrogenase [Streptomyces sviceus ATCC 29083]
 gi|197709910|gb|EDY53944.1| proline dehydrogenase [Streptomyces sviceus ATCC 29083]
Length=308

 Score =  310 bits (793),  Expect = 3e-82, Method: Compositional matrix adjust.
 Identities = 157/312 (51%), Positives = 212/312 (68%), Gaps = 6/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSDR+ R++  +P+T+ VV RF+PG+T+D++V IV  L   G  L++D +G
Sbjct  2    LGPVILAASRSDRMRRLISAAPVTKQVVDRFIPGETVDEIVPIVQELTSRGLELTMDVVG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E++T  + A AA  AYL L+D LG        G R  E+S+KLS  GQALD  G ++AL 
Sbjct  62   EDITTPEQAEAARDAYLALVDRLG----TLELGTRA-EMSVKLSMFGQALD-GGHELALA  115

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+QAYL RT AD   
Sbjct  116  NVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQAYLFRTEADARR  175

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LAA G+RVRL KGAY EPA VAY+   ++  +Y+R LR+L  G GYPMV +HDP +I+  
Sbjct  176  LAAAGSRVRLVKGAYKEPAEVAYQQKHEIDKAYVRALRILMEGEGYPMVGSHDPRLISIA  235

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              + R++GR   ++E+QMLYG+R DE  RL   G+ +RVY  +GT WYGYF+RRLAE+PA
Sbjct  236  QELARQAGRKPDEYEFQMLYGIRGDEHLRLAAEGHRMRVYTAYGTDWYGYFMRRLAEKPA  295

Query  309  NLAFFLRALTDR  320
            NL FF+R++  +
Sbjct  296  NLRFFVRSMISK  307


>gi|302522085|ref|ZP_07274427.1| proline dehydrogenase [Streptomyces sp. SPB78]
 gi|302430980|gb|EFL02796.1| proline dehydrogenase [Streptomyces sp. SPB78]
Length=308

 Score =  306 bits (785),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 156/312 (50%), Positives = 210/312 (68%), Gaps = 6/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSDRL R+V  +P+T+ VV RF+PG+++D +V I+      G  L++D +G
Sbjct  2    LGPVILAASRSDRLRRVVSAAPVTKPVVNRFIPGESVDQIVPIIVDATSKGLELTMDVVG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E++T  + AAAA  AYL L++ L      A D     E+S+KLS  GQAL+  G ++AL 
Sbjct  62   EDITTPEQAAAARDAYLELIEHLK-----ALDLGTRAEMSVKLSMFGQALE-GGHELALS  115

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+QAYL RT  D   
Sbjct  116  NVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQAYLFRTEDDARR  175

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LAA G+RVR+ KGAY EPASVAY++  ++  +Y+R LR+L  G GYPMV +HDP I+   
Sbjct  176  LAAAGSRVRVVKGAYKEPASVAYQEKPEIDKAYIRVLRILMEGDGYPMVGSHDPRIVEIA  235

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              + R +GR  GDFE+QMLYG+R +E  RL   G+ +RVY  +GT WYGYF+RRLAE+PA
Sbjct  236  QELARRAGRKPGDFEFQMLYGIRTEEHVRLAREGHRMRVYTAYGTDWYGYFMRRLAEKPA  295

Query  309  NLAFFLRALTDR  320
            NL FFLR++  +
Sbjct  296  NLLFFLRSVLTK  307


>gi|295836357|ref|ZP_06823290.1| proline dehydrogenase [Streptomyces sp. SPB74]
 gi|295825979|gb|EFG64591.1| proline dehydrogenase [Streptomyces sp. SPB74]
Length=308

 Score =  306 bits (785),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 157/312 (51%), Positives = 210/312 (68%), Gaps = 6/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSDRL R+V  +P+T+ VV RF+PG+++D +V I+      G  L++D +G
Sbjct  2    LGPVILAASRSDRLRRVVSAAPVTKPVVNRFIPGESVDQIVPIIVDATSKGLELTMDVVG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E++T  + AAAA  AYL L++ L      A D     E+S+KLS  GQAL+  G ++AL 
Sbjct  62   EDITTPEQAAAARDAYLELIEHLK-----ALDLGTRAEMSVKLSMFGQALE-GGHELALA  115

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+QAYL RT  D   
Sbjct  116  NVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQAYLFRTEDDARR  175

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LAA G+RVRL KGAY EPASVA+++  ++  +Y+R LRVL  G GYPMV +HDP I+   
Sbjct  176  LAAAGSRVRLVKGAYKEPASVAHQEKPEIDKAYIRVLRVLMEGDGYPMVGSHDPRIVEIA  235

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              + R +GR  GDFE+QMLYG+R +E  RL   G+ +RVY  +GT WYGYF+RRLAE+PA
Sbjct  236  QELARRAGRKPGDFEFQMLYGIRSEEHLRLAREGHRMRVYTAYGTDWYGYFMRRLAEKPA  295

Query  309  NLAFFLRALTDR  320
            NL FFLR++  +
Sbjct  296  NLLFFLRSVLTK  307


>gi|318061799|ref|ZP_07980520.1| putative proline dehydrogenase [Streptomyces sp. SA3_actG]
 gi|333024240|ref|ZP_08452304.1| putative proline dehydrogenase [Streptomyces sp. Tu6071]
 gi|332744092|gb|EGJ74533.1| putative proline dehydrogenase [Streptomyces sp. Tu6071]
Length=345

 Score =  306 bits (785),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 156/312 (50%), Positives = 210/312 (68%), Gaps = 6/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSDRL R+V  +P+T+ VV RF+PG+++D +V I+      G  L++D +G
Sbjct  39   LGPVILAASRSDRLRRVVSAAPVTKPVVNRFIPGESVDQIVPIIVDATSKGLELTMDVVG  98

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E++T  + AAAA  AYL L++ L      A D     E+S+KLS  GQAL+  G ++AL 
Sbjct  99   EDITTPEQAAAARDAYLELIEHLK-----ALDLGTRAEMSVKLSMFGQALE-GGHELALS  152

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+QAYL RT  D   
Sbjct  153  NVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQAYLFRTEDDARR  212

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LAA G+RVR+ KGAY EPASVAY++  ++  +Y+R LR+L  G GYPMV +HDP I+   
Sbjct  213  LAAAGSRVRVVKGAYKEPASVAYQEKPEIDKAYIRVLRILMEGDGYPMVGSHDPRIVEIA  272

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              + R +GR  GDFE+QMLYG+R +E  RL   G+ +RVY  +GT WYGYF+RRLAE+PA
Sbjct  273  QELARRAGRKPGDFEFQMLYGIRTEEHVRLAREGHRMRVYTAYGTDWYGYFMRRLAEKPA  332

Query  309  NLAFFLRALTDR  320
            NL FFLR++  +
Sbjct  333  NLLFFLRSVLTK  344


>gi|318076679|ref|ZP_07984011.1| putative proline dehydrogenase [Streptomyces sp. SA3_actF]
Length=320

 Score =  306 bits (785),  Expect = 3e-81, Method: Compositional matrix adjust.
 Identities = 156/313 (50%), Positives = 210/313 (68%), Gaps = 6/313 (1%)

Query  8    TLRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYL  67
             L P +LAA RSDRL R+V  +P+T+ VV RF+PG+++D +V I+      G  L++D +
Sbjct  13   VLGPVILAASRSDRLRRVVSAAPVTKPVVNRFIPGESVDQIVPIIVDATSKGLELTMDVV  72

Query  68   GENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIAL  127
            GE++T  + AAAA  AYL L++ L      A D     E+S+KLS  GQAL+  G ++AL
Sbjct  73   GEDITTPEQAAAARDAYLELIEHLK-----ALDLGTRAEMSVKLSMFGQALE-GGHELAL  126

Query  128  DNARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCA  187
             N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+QAYL RT  D  
Sbjct  127  SNVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQAYLFRTEDDAR  186

Query  188  ELAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAA  247
             LAA G+RVR+ KGAY EPASVAY++  ++  +Y+R LR+L  G GYPMV +HDP I+  
Sbjct  187  RLAAAGSRVRVVKGAYKEPASVAYQEKPEIDKAYIRVLRILMEGDGYPMVGSHDPRIVEI  246

Query  248  VPGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERP  307
               + R +GR  GDFE+QMLYG+R +E  RL   G+ +RVY  +GT WYGYF+RRLAE+P
Sbjct  247  AQELARRAGRKPGDFEFQMLYGIRTEEHVRLAREGHRMRVYTAYGTDWYGYFMRRLAEKP  306

Query  308  ANLAFFLRALTDR  320
            ANL FFLR++  +
Sbjct  307  ANLLFFLRSVLTK  319


>gi|291454326|ref|ZP_06593716.1| proline dehydrogenase [Streptomyces albus J1074]
 gi|291357275|gb|EFE84177.1| proline dehydrogenase [Streptomyces albus J1074]
Length=308

 Score =  306 bits (783),  Expect = 4e-81, Method: Compositional matrix adjust.
 Identities = 157/312 (51%), Positives = 210/312 (68%), Gaps = 6/312 (1%)

Query  9    LRPAMLAAGRSDRLGRIVERSPLTRGVVRRFVPGDTLDDVVDIVTALRDSGRYLSIDYLG  68
            L P +LAA RSD++ R+V  +P+T+ VV RF+PG+T+D VV IV     SG  L++D +G
Sbjct  2    LGPVILAASRSDKMRRLVSAAPVTKQVVDRFIPGETVDAVVPIVQEAVASGLELTMDVVG  61

Query  69   ENVTDADDAAAAVRAYLGLLDVLGRRGDIACDGVRPLEVSLKLSALGQALDRDGQKIALD  128
            E++T  + AAAA  AYL L+D    R  +   G +  E+S+KLS  GQAL+  G ++AL 
Sbjct  62   EDITTPEQAAAARDAYLELID----RLKVLGHGTKA-EMSVKLSMFGQALE-GGHELALA  115

Query  129  NARAICERAERVGAWVTVDAEDHTTTDSTLSISGDLRVDFPWLGTVVQAYLRRTLADCAE  188
            N R + E A  +G  VT+DAEDHTT DS  +I  +LR DFP  G V+Q+YL RT  D   
Sbjct  116  NVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQSYLFRTEDDARR  175

Query  189  LAAVGARVRLCKGAYDEPASVAYRDAAQVTDSYLRCLRVLTAGRGYPMVATHDPVIIAAV  248
            LAA G+RVRL KGAY EPASVAY+D A +  +Y+R LR+L  G GYPMV +HDP ++A  
Sbjct  176  LAAAGSRVRLVKGAYKEPASVAYQDKADIDKAYVRVLRILMEGDGYPMVGSHDPRLVAIA  235

Query  249  PGITRESGRSQGDFEYQMLYGVRDDEQRRLTGAGNHVRVYVPFGTRWYGYFLRRLAERPA  308
              +   +GR   D+E+QMLYG+R DE  RL   G+ +RVY  +GT WYGYF+RRLAE+PA
Sbjct  236  QELAHRAGRKLDDYEFQMLYGIRSDEHHRLAAEGHRMRVYTAYGTDWYGYFMRRLAEKPA  295

Query  309  NLAFFLRALTDR  320
            NL FF R++  +
Sbjct  296  NLLFFFRSMLTK  307



Lambda     K      H
   0.324    0.139    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 583580000052


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40