BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1193 Length=473 Score E Sequences producing significant alignments: (Bits) Value gi|15608333|ref|NP_215709.1| acyl-CoA synthetase [Mycobacterium ... 930 0.0 gi|289757288|ref|ZP_06516666.1| fatty-acid-CoA ligase fadD36 [My... 926 0.0 gi|326902816|gb|EGE49749.1| fatty-acid-CoA ligase fadD36 [Mycoba... 924 0.0 gi|15827509|ref|NP_301772.1| acyl-CoA synthetase [Mycobacterium ... 744 0.0 gi|240169040|ref|ZP_04747699.1| acyl-CoA synthetase [Mycobacteri... 732 0.0 gi|254822881|ref|ZP_05227882.1| acyl-CoA synthetase [Mycobacteri... 726 0.0 gi|296170104|ref|ZP_06851704.1| acyl-CoA synthetase [Mycobacteri... 725 0.0 gi|118465336|ref|YP_880587.1| acyl-CoA synthetase [Mycobacterium... 717 0.0 gi|342862083|ref|ZP_08718726.1| acyl-CoA synthetase [Mycobacteri... 709 0.0 gi|336458685|gb|EGO37647.1| acyl-CoA synthetase (AMP-forming)/AM... 709 0.0 gi|41408678|ref|NP_961514.1| acyl-CoA synthetase [Mycobacterium ... 707 0.0 gi|118468796|ref|YP_889362.1| acyl-CoA synthetase [Mycobacterium... 698 0.0 gi|118616705|ref|YP_905037.1| acyl-CoA synthetase [Mycobacterium... 691 0.0 gi|183984215|ref|YP_001852506.1| fatty-acid-CoA synthetase, FadD... 691 0.0 gi|145222763|ref|YP_001133441.1| acyl-CoA synthetase [Mycobacter... 652 0.0 gi|120405474|ref|YP_955303.1| acyl-CoA synthetase [Mycobacterium... 650 0.0 gi|54026717|ref|YP_120959.1| acyl-CoA synthetase [Nocardia farci... 639 0.0 gi|325676443|ref|ZP_08156121.1| substrate-CoA ligase [Rhodococcu... 625 6e-177 gi|312138854|ref|YP_004006190.1| acyl-CoA ligase/synthetase [Rho... 623 2e-176 gi|229493925|ref|ZP_04387697.1| acyl-CoA synthetase [Rhodococcus... 622 6e-176 gi|169628425|ref|YP_001702074.1| acyl-CoA synthetase [Mycobacter... 621 7e-176 gi|333989812|ref|YP_004522426.1| fatty-acid-CoA synthetase [Myco... 620 2e-175 gi|111022917|ref|YP_705889.1| acyl-CoA synthetase [Rhodococcus j... 619 4e-175 gi|226365425|ref|YP_002783208.1| acyl-CoA synthetase [Rhodococcu... 616 3e-174 gi|226307665|ref|YP_002767625.1| fatty-acid--CoA ligase [Rhodoco... 610 1e-172 gi|108800984|ref|YP_641181.1| acyl-CoA synthetase [Mycobacterium... 599 4e-169 gi|262204578|ref|YP_003275786.1| AMP-dependent synthetase and li... 573 2e-161 gi|296139000|ref|YP_003646243.1| AMP-dependent synthetase and li... 566 3e-159 gi|325677455|ref|ZP_08157119.1| substrate-CoA ligase [Rhodococcu... 563 2e-158 gi|312137574|ref|YP_004004910.1| acyl-CoA ligase/synthetase [Rho... 563 2e-158 gi|333921022|ref|YP_004494603.1| putative acyl-CoA synthetase [A... 555 8e-156 gi|343928640|ref|ZP_08768085.1| putative fatty-acid--CoA ligase ... 546 3e-153 gi|302866959|ref|YP_003835596.1| AMP-dependent synthetase and li... 516 4e-144 gi|315506603|ref|YP_004085490.1| amp-dependent synthetase and li... 515 8e-144 gi|312200234|ref|YP_004020295.1| AMP-dependent synthetase and li... 501 8e-140 gi|229494260|ref|ZP_04388023.1| acyl-CoA synthetase family membe... 499 6e-139 gi|238063671|ref|ZP_04608380.1| acyl-CoA synthetase [Micromonosp... 494 1e-137 gi|145595459|ref|YP_001159756.1| acyl-CoA synthetase [Salinispor... 487 2e-135 gi|317506368|ref|ZP_07964179.1| AMP-binding enzyme [Segniliparus... 485 6e-135 gi|296393265|ref|YP_003658149.1| AMP-dependent synthetase and li... 483 3e-134 gi|159038692|ref|YP_001537945.1| acyl-CoA synthetase [Salinispor... 480 2e-133 gi|337766095|emb|CCB74806.1| Acyl-CoA synthetase [Streptomyces c... 477 2e-132 gi|345015718|ref|YP_004818072.1| AMP-dependent synthetase and li... 472 7e-131 gi|297561651|ref|YP_003680625.1| AMP-dependent synthetase and li... 468 1e-129 gi|86741668|ref|YP_482068.1| acyl-CoA synthetase [Frankia sp. Cc... 467 2e-129 gi|297157954|gb|ADI07666.1| acyl-CoA synthetase [Streptomyces bi... 466 5e-129 gi|302544822|ref|ZP_07297164.1| substrate-CoA ligase [Streptomyc... 466 5e-129 gi|311895109|dbj|BAJ27517.1| putative long-chain fatty-acid--CoA... 464 1e-128 gi|331694181|ref|YP_004330420.1| Long-chain-fatty-acid--CoA liga... 454 1e-125 gi|302539402|ref|ZP_07291744.1| O-succinylbenzoate-CoA ligase [S... 451 1e-124 >gi|15608333|ref|NP_215709.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv] gi|15840636|ref|NP_335673.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551] gi|31792386|ref|NP_854879.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] 71 more sequence titles Length=473 Score = 930 bits (2403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/473 (99%), Positives = 473/473 (100%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV Sbjct 1 MLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW Sbjct 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY Sbjct 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG Sbjct 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP Sbjct 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA Sbjct 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA Sbjct 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG Sbjct 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 >gi|289757288|ref|ZP_06516666.1| fatty-acid-CoA ligase fadD36 [Mycobacterium tuberculosis T85] gi|294993377|ref|ZP_06799068.1| acyl-CoA synthetase [Mycobacterium tuberculosis 210] gi|289712852|gb|EFD76864.1| fatty-acid-CoA ligase fadD36 [Mycobacterium tuberculosis T85] gi|339294183|gb|AEJ46294.1| acyl-CoA synthetase [Mycobacterium tuberculosis CCDC5079] gi|339297824|gb|AEJ49934.1| acyl-CoA synthetase [Mycobacterium tuberculosis CCDC5180] Length=473 Score = 926 bits (2394), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/473 (99%), Positives = 472/473 (99%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV Sbjct 1 MLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW Sbjct 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRY EPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY Sbjct 121 HRYLEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG Sbjct 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP Sbjct 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA Sbjct 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA Sbjct 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG Sbjct 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 >gi|326902816|gb|EGE49749.1| fatty-acid-CoA ligase fadD36 [Mycobacterium tuberculosis W-148] Length=473 Score = 924 bits (2389), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/473 (99%), Positives = 471/473 (99%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV Sbjct 1 MLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW Sbjct 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRY EPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY Sbjct 121 HRYLEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFF VPTVWSRVAADQAAAG Sbjct 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFEVPTVWSRVAADQAAAG 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP Sbjct 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA Sbjct 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA Sbjct 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG Sbjct 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 >gi|15827509|ref|NP_301772.1| acyl-CoA synthetase [Mycobacterium leprae TN] gi|221229986|ref|YP_002503402.1| acyl-CoA synthetase [Mycobacterium leprae Br4923] gi|699196|gb|AAA62961.1| xclC [Mycobacterium leprae] gi|13093059|emb|CAC31432.1| acyl-CoA synthase [Mycobacterium leprae] gi|219933093|emb|CAR71146.1| acyl-CoA synthase [Mycobacterium leprae Br4923] Length=476 Score = 744 bits (1920), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/476 (82%), Positives = 423/476 (89%), Gaps = 3/476 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNP+VV+A DIADAV +DG VLSRS LVGAATSVAERV GA VAVLATPTASTV Sbjct 1 MLLASLNPSVVTATDIADAVCVDGVVLSRSGLVGAATSVAERVGGARLVAVLATPTASTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDD---PAGLPHIPVRTHA 117 LAITGCLIAGVPVVPVPAD+GV ERRHMLTDSG QAWLGP P P GLPHIPV+ A Sbjct 61 LAITGCLIAGVPVVPVPADIGVVERRHMLTDSGAQAWLGPGPSADSAPDGLPHIPVQLDA 120 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 RSW+RYPEPSP A AMV+YTSGTTGPPKGV LSRRAIA DLDALA+AWQWTA+DVLVHGL Sbjct 121 RSWNRYPEPSPDATAMVIYTSGTTGPPKGVLLSRRAIAVDLDALAQAWQWTADDVLVHGL 180 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PL+HVHGLVLGLLGSLR GNRFVHTGKPTP YAQAC EA G+L+FGVPTVWSR+ AD+A Sbjct 181 PLFHVHGLVLGLLGSLRIGNRFVHTGKPTPTAYAQACSEAGGSLYFGVPTVWSRLVADEA 240 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 A AL+PARLLVSGSA+LPVPVFD+L LTGHRP+ERYG++ESLITLST ADGERR GWV Sbjct 241 VARALRPARLLVSGSASLPVPVFDRLAHLTGHRPIERYGSTESLITLSTLADGERRAGWV 300 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPLAGVQTRLVD+ GG VP+DGETVG+LQVR PT+F GYLN+P+ATA AFD D WYRTG Sbjct 301 GLPLAGVQTRLVDESGGPVPYDGETVGRLQVRSPTMFGGYLNRPEATAEAFDEDGWYRTG 360 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAVVD GMHRIVGRESVDLIK GGYR+GAGEIE LLGHPDV E AVVG+PD+DLGQR Sbjct 361 DVAVVDSGGMHRIVGRESVDLIKLGGYRIGAGEIEMALLGHPDVREVAVVGLPDEDLGQR 420 Query 418 IVAYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 IVA+VVG+ +DAD LIN+VAQQLS+HKRPREVR VDALPRNA+GKVLKKQLL EG Sbjct 421 IVAFVVGAEALDADELINYVAQQLSIHKRPREVRFVDALPRNAMGKVLKKQLLFEG 476 >gi|240169040|ref|ZP_04747699.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=467 Score = 732 bits (1889), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/473 (86%), Positives = 433/473 (92%), Gaps = 6/473 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPA +S DIADA+ IDG LSRSDL+GAATSVAERVAGAHRVAVLATPTA+TV Sbjct 1 MLLASLNPADLSTTDIADAISIDGVTLSRSDLIGAATSVAERVAGAHRVAVLATPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCL+AGV VVPVPADVGV ERRHML DSG QAWLGP+P + GLPHIPVR ARSW Sbjct 61 LAVTGCLLAGVQVVPVPADVGVAERRHMLADSGAQAWLGPVPAETEGLPHIPVRLRARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEPSP +AMV+YTSGTTGPPKGVQLSRRAIAADLDALA+AWQWTA+DVLVHGLP+Y Sbjct 121 HRYPEPSPDDVAMVIYTSGTTGPPKGVQLSRRAIAADLDALADAWQWTADDVLVHGLPMY 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTPAGYA A GTL+FGVPTVWSRVAADQAAA Sbjct 181 HVHGLVLGLLGSLRVGNRFVHTGKPTPAGYAAAG----GTLYFGVPTVWSRVAADQAAAE 236 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 ALKPARLLVSGSAALPVPVFDKLV ++GHRP+ERYGASESLIT+STRADGERRPGWVGLP Sbjct 237 ALKPARLLVSGSAALPVPVFDKLVAVSGHRPIERYGASESLITVSTRADGERRPGWVGLP 296 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGVQTRLVDD+G VPHDGETVG+LQV+GPT+F+GYLN+PDATA AFDAD WYRTGDVA Sbjct 297 LAGVQTRLVDDNGDPVPHDGETVGRLQVQGPTMFEGYLNRPDATAEAFDADGWYRTGDVA 356 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVD GMHRIVGRESVDLIKSGG+R+GAGEIETVLLGHPDVAE AVVG PD DLGQRIVA Sbjct 357 VVDAGGMHRIVGRESVDLIKSGGFRIGAGEIETVLLGHPDVAEVAVVGFPDADLGQRIVA 416 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 YVVGSAN D LI FVAQQLSVHKRPREVRIV++LPRNALGKVLKKQLLSEG Sbjct 417 YVVGSAN--PDDLIQFVAQQLSVHKRPREVRIVESLPRNALGKVLKKQLLSEG 467 >gi|254822881|ref|ZP_05227882.1| acyl-CoA synthetase [Mycobacterium intracellulare ATCC 13950] Length=474 Score = 726 bits (1873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/476 (83%), Positives = 426/476 (90%), Gaps = 5/476 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASL+P+V++A D+ADAVRIDG VLSRSDL GAATSVAERV GA RVA+LA PTA+TV Sbjct 1 MLLASLDPSVLTATDVADAVRIDGTVLSRSDLAGAATSVAERVGGAGRVAILAAPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDD---PAGLPHIPVRTHA 117 LA+TGCLIAGVP VPVPADVG ERRHMLTDSG QAWLG P P GLPHIPVR HA Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLTDSGAQAWLGAAPPKDSAPEGLPHIPVRLHA 120 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 RSWHRYPEPSP A AM++YTSGTTG PKGV LSRRAIAADLDALA+AWQWTA+DVLVHGL Sbjct 121 RSWHRYPEPSPDATAMIIYTSGTTGLPKGVVLSRRAIAADLDALAQAWQWTADDVLVHGL 180 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PL+HVHGLVLGLLGSLR GNRF+HTGKPTP GYAQA + GTLFFGVPTVWSRV AD+A Sbjct 181 PLFHVHGLVLGLLGSLRVGNRFIHTGKPTPEGYAQARTDFGGTLFFGVPTVWSRVGADEA 240 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 AA AL PARLLVSGSA LPVPVFD+L LTGH+PVERYGASESLIT+STRADGERRPGWV Sbjct 241 AARALGPARLLVSGSAPLPVPVFDRLAALTGHQPVERYGASESLITISTRADGERRPGWV 300 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPLAGVQTR++DDDG VPHDGETVGKL VRGP +FDGYLN+PDATA AFDAD WYRTG Sbjct 301 GLPLAGVQTRVLDDDGAAVPHDGETVGKLHVRGPMMFDGYLNRPDATAEAFDADGWYRTG 360 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAV+DG GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP V EAAVVG+PD DLGQR Sbjct 361 DVAVIDGGGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPGVQEAAVVGMPDADLGQR 420 Query 418 IVAYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 IVAY+VGSAN D LI++VAQQLSVHKRPREVR+VD LPRNA+GKVLKK+LLS+G Sbjct 421 IVAYIVGSAN--GDELIDYVAQQLSVHKRPREVRVVDTLPRNAMGKVLKKELLSDG 474 >gi|296170104|ref|ZP_06851704.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895246|gb|EFG74958.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=473 Score = 725 bits (1871), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/473 (84%), Positives = 435/473 (92%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPA V+A D+ DAVRIDG VLSRSDLVGAATSVAERVAGA RVA+LATPTA+TV Sbjct 1 MLLASLNPAAVTATDVPDAVRIDGAVLSRSDLVGAATSVAERVAGADRVAILATPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCLIAGVP VPVPADVG ERRHMLTDS QAWLGP+PD+ GLPHIPVR HARSW Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLTDSAAQAWLGPVPDEAEGLPHIPVRLHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEP P A AM++YTSGTTG PKGV LSRRAIAADLDALA+AWQWTA+DVLVHGLPL+ Sbjct 121 HRYPEPPPHATAMIIYTSGTTGLPKGVVLSRRAIAADLDALAQAWQWTADDVLVHGLPLF 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTPAGYA+AC EA GTLFFGVPTVWSRV AD+AAA Sbjct 181 HVHGLVLGLLGSLRMGNRFVHTGKPTPAGYARACSEAGGTLFFGVPTVWSRVVADEAAAR 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSA LPVPVFD L +LTGH+P+ERYGASESLIT+STRADGERRPGWVGLP Sbjct 241 ALRPARLLVSGSAPLPVPVFDGLARLTGHQPIERYGASESLITVSTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGVQTRL+DD GG VPHDGETVG+L+VRGP +FDGYLN+P+ATAAAFD D WYRTGDVA Sbjct 301 LAGVQTRLLDDAGGPVPHDGETVGRLEVRGPMMFDGYLNRPEATAAAFDDDGWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 V+D +GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP V E AVVG+PD+DLGQRIVA Sbjct 361 VIDAAGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPGVREVAVVGMPDEDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 +VVG+ ++ADGLI++VAQ+LSVHKRPREVR+VDALPRNA+GKVLKKQLLS G Sbjct 421 FVVGAPELNADGLIDYVAQELSVHKRPREVRLVDALPRNAMGKVLKKQLLSGG 473 >gi|118465336|ref|YP_880587.1| acyl-CoA synthetase [Mycobacterium avium 104] gi|254774220|ref|ZP_05215736.1| acyl-CoA synthetase [Mycobacterium avium subsp. avium ATCC 25291] gi|118166623|gb|ABK67520.1| acyl-CoA synthase [Mycobacterium avium 104] Length=473 Score = 717 bits (1851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/473 (84%), Positives = 431/473 (92%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL SLNP+ V+A DI DAVRIDG VLSR+DL+GAATSVAERVAGA RVAVLATPTA+TV Sbjct 1 MLLTSLNPSAVTATDIPDAVRIDGTVLSRADLLGAATSVAERVAGAGRVAVLATPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCLIAGVP VPVPADVG ERRHML DSGV+AWLGPLPD+P GLPH+PVR HARSW Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLADSGVRAWLGPLPDEPDGLPHVPVRLHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEPSP A AM++YTSGTTG PKGV LSRRAIAADLDALA+AWQWTA+DVLVHGLPL+ Sbjct 121 HRYPEPSPDATAMIIYTSGTTGLPKGVVLSRRAIAADLDALAQAWQWTADDVLVHGLPLF 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTPAGYAQA + GTLFFGVPTVWSRV AD+AAA Sbjct 181 HVHGLVLGLLGSLRIGNRFVHTGKPTPAGYAQARTDFGGTLFFGVPTVWSRVVADEAAAR 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSA LPVPVFD+L LTGH+PVERYGASESLIT+STRADGERRPGWVGLP Sbjct 241 ALRPARLLVSGSAPLPVPVFDRLAGLTGHQPVERYGASESLITISTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 L GVQTR+VDDDG VPHDGETVGKL VRGP +FDGYLN+PDATA AFDAD WYRTGDVA Sbjct 301 LTGVQTRVVDDDGNPVPHDGETVGKLLVRGPMMFDGYLNRPDATAEAFDADGWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVD +GMHRIVGRESVDLIKSGGYR+GAGEIET LLGHP VAEAAVVG+PD+DLGQRIVA Sbjct 361 VVDDAGMHRIVGRESVDLIKSGGYRIGAGEIETALLGHPGVAEAAVVGMPDEDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 +VV + V+ D LI+ VAQQLS+HKRPREVR+VDALPRNA+GKVLKKQLLS+G Sbjct 421 FVVPAGRVNPDDLIDHVAQQLSIHKRPREVRVVDALPRNAMGKVLKKQLLSDG 473 >gi|342862083|ref|ZP_08718726.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035] gi|342130387|gb|EGT83702.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035] Length=471 Score = 709 bits (1831), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/473 (83%), Positives = 428/473 (91%), Gaps = 2/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASL+P+V++ D+ADAVRIDG V SRSDL GAATSVAERV GA RVA+LA PTA+TV Sbjct 1 MLLASLDPSVLTTTDVADAVRIDGTVFSRSDLPGAATSVAERVGGAGRVAILAAPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCLIAGVP VPVPADVG ERRHMLTDSGV+AWLGP PD+ GLPHIPVR HARSW Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLTDSGVKAWLGPAPDEAEGLPHIPVRLHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRY EPSP A AM++YTSGTTG PKGV LSRRAIAADLDALAEAWQWTA+DVLVHGLPL+ Sbjct 121 HRYAEPSPDATAMIIYTSGTTGLPKGVVLSRRAIAADLDALAEAWQWTADDVLVHGLPLF 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRF+HTGKPTPAGYAQA + GTLFFGVPTVWSRV D+AAA Sbjct 181 HVHGLVLGLLGSLRIGNRFIHTGKPTPAGYAQAATDHGGTLFFGVPTVWSRVVGDEAAAR 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSAALPVPVFD+L LTGH+P+ERYGASESLITLSTRADGERRPGWVGLP Sbjct 241 ALRPARLLVSGSAALPVPVFDRLAGLTGHQPIERYGASESLITLSTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 L GVQTR++DDDGG VPHDGETVGKL VRGP +FDGYLN+PDATA AFD D WYRTGDVA Sbjct 301 LTGVQTRVLDDDGGLVPHDGETVGKLHVRGPMMFDGYLNRPDATAEAFDTDGWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 V+DG GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP V EAAVVG+PD DLGQRIVA Sbjct 361 VIDGDGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPGVQEAAVVGMPDADLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 ++VGSA D D LI++VAQ+LSVHKRPREVRIVDALPRNA+GKVLKK+LL++G Sbjct 421 FIVGSA--DGDALIDYVAQELSVHKRPREVRIVDALPRNAMGKVLKKRLLTDG 471 >gi|336458685|gb|EGO37647.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium avium subsp. paratuberculosis S397] Length=473 Score = 709 bits (1831), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/473 (84%), Positives = 429/473 (91%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL SLNP+ V+A DI DAVRIDG VLSR+DL+GAATSVAERVAGA RVAVLATPTA+TV Sbjct 1 MLLTSLNPSAVTATDIPDAVRIDGTVLSRADLLGAATSVAERVAGAGRVAVLATPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCLIAGVP VPVPADVG ERRHML DSGV+AWLGPLPD+P GLPH+PVR HARSW Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLADSGVRAWLGPLPDEPDGLPHVPVRLHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEPSP A AM++YTSGTTG PKGV LSRR IAADLDALAEAWQWTA+DVLVHGLPL+ Sbjct 121 HRYPEPSPDATAMIIYTSGTTGLPKGVVLSRRTIAADLDALAEAWQWTADDVLVHGLPLF 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTPAGYAQA + GTLFFGVPTVWSRV AD AAA Sbjct 181 HVHGLVLGLLGSLRIGNRFVHTGKPTPAGYAQARTDFGGTLFFGVPTVWSRVVADDAAAR 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSA LPVPVFD+L LTGH+PVERYGASESLIT+STRADGERRPGWVGLP Sbjct 241 ALRPARLLVSGSAPLPVPVFDRLAGLTGHQPVERYGASESLITISTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 L GVQTR+VDDDG VPHDGETVGKL VRGP +FDGYLN+PDATA AFDAD WYRTGDVA Sbjct 301 LTGVQTRVVDDDGNPVPHDGETVGKLLVRGPMMFDGYLNRPDATAEAFDADGWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVD +GMHRIVGRESVDLIKSGGYR+GAGEIET LLGHP VAEAAVVG+PD+DLGQRIVA Sbjct 361 VVDDAGMHRIVGRESVDLIKSGGYRIGAGEIETALLGHPGVAEAAVVGMPDEDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 +VV + V+ D LI+ VAQQLS+HKRPREVR+VDALPRNA+GKVLKKQLLS+G Sbjct 421 FVVPAGRVNPDDLIDHVAQQLSIHKRPREVRVVDALPRNAMGKVLKKQLLSDG 473 >gi|41408678|ref|NP_961514.1| acyl-CoA synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397036|gb|AAS04897.1| FadD36 [Mycobacterium avium subsp. paratuberculosis K-10] Length=473 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/473 (84%), Positives = 430/473 (91%), Gaps = 0/473 (0%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL SLNP+ V+A DI DAVRIDG VLSR+DL+GAATSVAERVAGA RVAVLATPTA+TV Sbjct 1 MLLTSLNPSAVTATDIPDAVRIDGTVLSRADLLGAATSVAERVAGAGRVAVLATPTAATV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+TGCLIAGVP VPVPADVG ERRHML DSGV+AWLGPLPD+P GLPH+PVR HARSW Sbjct 61 LAVTGCLIAGVPFVPVPADVGAAERRHMLADSGVRAWLGPLPDEPDGLPHVPVRLHARSW 120 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HRYPEPSP A AM++YTSGTTG PKGV LSRRAIAADLDALAEAWQWTA+DVLVHGLPL+ Sbjct 121 HRYPEPSPDATAMIIYTSGTTGLPKGVVLSRRAIAADLDALAEAWQWTADDVLVHGLPLF 180 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTPAGYAQA + GTLFFGVPTVWSRV AD AAA Sbjct 181 HVHGLVLGLLGSLRIGNRFVHTGKPTPAGYAQARTDFGGTLFFGVPTVWSRVVADDAAAR 240 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSA LPVPVFD+L LTGH+PVERYGASESLIT+STRADGERRPGWVGLP Sbjct 241 ALRPARLLVSGSAPLPVPVFDRLAGLTGHQPVERYGASESLITISTRADGERRPGWVGLP 300 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 L GVQTR+VDDDG VPHDGETVGKL VRGP +FDGYLN+PDATA AFDAD WYRTGDVA Sbjct 301 LTGVQTRVVDDDGNPVPHDGETVGKLLVRGPMMFDGYLNRPDATAEAFDADGWYRTGDVA 360 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 VVD +GMHRIVGRESVDLIKSGGYR+GAGEIET LLGHP VAEAAVVG+PD+DLGQRIVA Sbjct 361 VVDDAGMHRIVGRESVDLIKSGGYRIGAGEIETALLGHPGVAEAAVVGMPDEDLGQRIVA 420 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 +VV + V+ D LI+ VAQQLS+HKRPREVR+VDALPRNA+GKVLKKQLLS+G Sbjct 421 FVVPAGRVNPDDLIDHVAQQLSIHKRPREVRVVDALPRNAMGKVLKKQLLSDG 473 >gi|118468796|ref|YP_889362.1| acyl-CoA synthetase [Mycobacterium smegmatis str. MC2 155] gi|118170083|gb|ABK70979.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155] Length=468 Score = 698 bits (1802), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/470 (76%), Positives = 403/470 (86%), Gaps = 7/470 (1%) Query 1 VLLASLNPAVVSAADIADAV-RIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LLASLNPA V+A RIDG VLSRSDLVG ATSVAERVA A RVAVLA PTA+T Sbjct 1 MLLASLNPAAVAAGADIADAVRIDGAVLSRSDLVGGATSVAERVAVAQRVAVLAKPTATT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLAITGCLIAGV VVPVPADVGV ERRHML DSG QAWLG PDD GLPHIPVR HARS Sbjct 61 VLAITGCLIAGVTVVPVPADVGVAERRHMLEDSGAQAWLGERPDDAEGLPHIPVRLHARS 120 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WHRY EP P + A+++YTSGTTG PKGV ++R AIAAD+D LA+AW+WT ED LVHGLPL Sbjct 121 WHRYAEPPPESTAIIMYTSGTTGLPKGVPITRNAIAADIDGLAKAWEWTPEDTLVHGLPL 180 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGLVLGL+GSLR GNRFVHTGKPTP YA EA GTL+FGVPTVWSRV + AA Sbjct 181 FHVHGLVLGLIGSLRIGNRFVHTGKPTPERYA----EAKGTLYFGVPTVWSRVVNNLDAA 236 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF++L +LTG PVERYG++ESLIT++T +GERRPGWVG+ Sbjct 237 LALSSARLLVSGSAPLPVPVFEQLTKLTGQPPVERYGSTESLITITTLVNGERRPGWVGV 296 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 P+ GV+TRLVD++G EVPHDGET+G+LQ++GPT+F+GYLN+P+ATA AFD D W+RTGDV Sbjct 297 PIEGVRTRLVDENGAEVPHDGETIGRLQIKGPTVFEGYLNRPEATAEAFDDDGWFRTGDV 356 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP V EAAVVGVPDDDLGQRIV Sbjct 357 AVIDAGGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPGVKEAAVVGVPDDDLGQRIV 416 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 AYVVG A ++D LI+FVA+QLSVHKRPREVRIVD+LPRNA+GKVLKK+L Sbjct 417 AYVVGDA--ESDTLIDFVAKQLSVHKRPREVRIVDSLPRNAMGKVLKKEL 464 >gi|118616705|ref|YP_905037.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118568815|gb|ABL03566.1| fatty-acid-CoA synthetase, FadD36 [Mycobacterium ulcerans Agy99] Length=472 Score = 691 bits (1783), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/476 (85%), Positives = 431/476 (91%), Gaps = 7/476 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPA VSA DIADAVRIDG LSRSDL+GAAT+VAER+AGAH+VAVLATPT STV Sbjct 1 MLLASLNPAAVSADDIADAVRIDGVDLSRSDLLGAATAVAERIAGAHQVAVLATPTVSTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPD---DPAGLPHIPVRTHA 117 LA+TGCLIAGVPVVPVPADVGV ERRHML DSG AWLGP P +P GLP IPVR HA Sbjct 61 LAVTGCLIAGVPVVPVPADVGVAERRHMLADSGAVAWLGPAPAQDAEPDGLPQIPVRLHA 120 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 RSWHRYPEP P ++AMV+YTSGTTG PKGVQLSRRAIAADLDALA+AWQW AEDVLVHGL Sbjct 121 RSWHRYPEPPPDSVAMVIYTSGTTGLPKGVQLSRRAIAADLDALAQAWQWNAEDVLVHGL 180 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PLYHVHGLVLGLLGSLR GNRFVHTGKPT AGYAQA GTL+FGVPTVWSRVAAD+A Sbjct 181 PLYHVHGLVLGLLGSLRVGNRFVHTGKPTAAGYAQAG----GTLYFGVPTVWSRVAADRA 236 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 AA AL+PARLLVSGSAALPVPVFD+LV L GHRP+ERYG+SESLITLSTRADG+RR GWV Sbjct 237 AAEALRPARLLVSGSAALPVPVFDQLVHLAGHRPIERYGSSESLITLSTRADGDRRAGWV 296 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPLAGVQTRLVDD G VPHDGETVGKLQVRG TLFDGYLN+P+ATA AFDAD WYRTG Sbjct 297 GLPLAGVQTRLVDDHGNPVPHDGETVGKLQVRGSTLFDGYLNRPEATAEAFDADGWYRTG 356 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAVVD GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP+V EAAVVG+PD+DLGQR Sbjct 357 DVAVVDDGGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPEVQEAAVVGLPDEDLGQR 416 Query 418 IVAYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 IVAY+VGS +D D LI+FVAQQLSVHKRPREVRIV++LPRNALGKVLKKQLLSEG Sbjct 417 IVAYIVGSDRIDPDVLIDFVAQQLSVHKRPREVRIVESLPRNALGKVLKKQLLSEG 472 >gi|183984215|ref|YP_001852506.1| fatty-acid-CoA synthetase, FadD36 [Mycobacterium marinum M] gi|183177541|gb|ACC42651.1| fatty-acid-CoA synthetase, FadD36 [Mycobacterium marinum M] Length=472 Score = 691 bits (1782), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/476 (85%), Positives = 430/476 (91%), Gaps = 7/476 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LLASLNPA VSA DIADAV IDG LSRSDL+GAAT+VAER+AGAHRVAVLATPT STV Sbjct 1 MLLASLNPAAVSADDIADAVCIDGVDLSRSDLLGAATAVAERIAGAHRVAVLATPTVSTV 60 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPD---DPAGLPHIPVRTHA 117 LA+TGCLIAGVPVVPVPADVGV ERRHML DSG AWLGP P +P GLP IPVR HA Sbjct 61 LAVTGCLIAGVPVVPVPADVGVAERRHMLADSGAVAWLGPAPAQDAEPDGLPQIPVRLHA 120 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 RSWHRYPEP P ++AMV+YTSGTTG PKGVQLSRRAIAADLDALA+AWQW AEDVLVHGL Sbjct 121 RSWHRYPEPPPDSVAMVIYTSGTTGLPKGVQLSRRAIAADLDALAQAWQWNAEDVLVHGL 180 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PLYHVHGLVLGLLGSLR GNRFVHTGKPT AGYAQA GTL+FGVPTVWSRVAAD+A Sbjct 181 PLYHVHGLVLGLLGSLRVGNRFVHTGKPTAAGYAQAG----GTLYFGVPTVWSRVAADRA 236 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 AA AL+PARLLVSGSAALPVPVFD+LV L GHRP+ERYG+SESLITLSTRADGERR GWV Sbjct 237 AAEALRPARLLVSGSAALPVPVFDQLVHLAGHRPIERYGSSESLITLSTRADGERRAGWV 296 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPLAGVQTRLVDD G VPHDGETVGKLQVRG TLFDGYLN+P+ATA AFDAD WYRTG Sbjct 297 GLPLAGVQTRLVDDHGNPVPHDGETVGKLQVRGSTLFDGYLNRPEATAEAFDADGWYRTG 356 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAVVD GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP+V EAAVVG+PD+DLGQR Sbjct 357 DVAVVDDGGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPEVQEAAVVGLPDEDLGQR 416 Query 418 IVAYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 IVAY+VGS +D D LI+FVAQQLSVHKRPREVRIV++LPRNALGKVLKKQLLSEG Sbjct 417 IVAYIVGSDRIDPDVLIDFVAQQLSVHKRPREVRIVESLPRNALGKVLKKQLLSEG 472 >gi|145222763|ref|YP_001133441.1| acyl-CoA synthetase [Mycobacterium gilvum PYR-GCK] gi|315443230|ref|YP_004076109.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|145215249|gb|ABP44653.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|315261533|gb|ADT98274.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=472 Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/470 (75%), Positives = 394/470 (84%), Gaps = 3/470 (0%) Query 1 VLLASLNPAVVSA-ADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LLASLNPA V+A AD+ DAVRIDG LSRSDLVGAATSVAERVAGA RVA+LA P+A+T Sbjct 1 MLLASLNPAAVAAGADLGDAVRIDGVSLSRSDLVGAATSVAERVAGASRVAILARPSATT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+ GCLIAGVP VPVPADVG ERRH+LTDSG Q WLG LPDD GL HIPVR HARS Sbjct 61 VLAVAGCLIAGVPFVPVPADVGAAERRHILTDSGAQGWLGELPDDADGLAHIPVRMHARS 120 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WHRY EP P A AM++YTSGTTG PKGV +SRRAIAAD+D LA+AWQWT+ED LVHGLP+ Sbjct 121 WHRYAEPPPDATAMIIYTSGTTGLPKGVVVSRRAIAADIDMLAQAWQWTSEDTLVHGLPM 180 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 YHVHGLVLGLLGSLR GNRFVHTGKP P YA A E GTL FGVPTVWSR+ D AA Sbjct 181 YHVHGLVLGLLGSLRIGNRFVHTGKPKPEAYAHAVSELGGTLLFGVPTVWSRIVEDGDAA 240 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL PARLLVSGSAALPVPVFD L LTGH+P+ERYG++E+LITLST GERRPGWVG+ Sbjct 241 RALAPARLLVSGSAALPVPVFDGLAALTGHQPIERYGSTETLITLSTLVSGERRPGWVGM 300 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 L GVQTR+V +DG +PHD E++G+L V+ PTLFDGYLN+ DATA D WYRTGDV Sbjct 301 ALPGVQTRVVAEDGTALPHDAESIGQLHVQSPTLFDGYLNRADATAEVLGEDGWYRTGDV 360 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D GMHRIVGRESVDLIKSGG+R+GAGEIETVLLGHP V EAAV+G PD+DLGQRIV Sbjct 361 AVIDPDGMHRIVGRESVDLIKSGGFRIGAGEIETVLLGHPGVREAAVIGAPDEDLGQRIV 420 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A+VVG A D LI+ VA++LSVHKRPREVRIVD LPRNA+GKV+KK+L Sbjct 421 AFVVGEAQ--PDELIDHVARELSVHKRPREVRIVDGLPRNAMGKVMKKEL 468 >gi|120405474|ref|YP_955303.1| acyl-CoA synthetase [Mycobacterium vanbaalenii PYR-1] gi|119958292|gb|ABM15297.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=472 Score = 650 bits (1676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/470 (77%), Positives = 402/470 (86%), Gaps = 3/470 (0%) Query 1 VLLASLNPAVVSA-ADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LLASLNPA V+A AD+ DAVRIDG LSRSDLVGAATSVAERV GA RVAVLATPTA+T Sbjct 1 MLLASLNPAAVAAGADLGDAVRIDGVSLSRSDLVGAATSVAERVGGASRVAVLATPTAAT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+TGCLIAGVPVVPVPADVG ERRH+L DS QAWLG LP++ GLPH+PVR HARS Sbjct 61 VLAVTGCLIAGVPVVPVPADVGAAERRHILADSRAQAWLGELPEEAEGLPHVPVRLHARS 120 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WHRYPEPSP A A+++YTSGTTGPPKGV +SRRAIAAD+D LA+AW+WT +D LVHGLPL Sbjct 121 WHRYPEPSPDAAALIIYTSGTTGPPKGVVVSRRAIAADIDMLAQAWEWTPQDTLVHGLPL 180 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 YHVHGLVLGLLGSLR GNRFVHTGKP PA YA+A E GTL FGVPTVWSRV D AA Sbjct 181 YHVHGLVLGLLGSLRVGNRFVHTGKPKPAAYARAVRELGGTLLFGVPTVWSRVVEDGDAA 240 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL PARLLVSGSAALPVPVFD L L+GHR +ERYG++E+LITLST A GERRPGWVGL Sbjct 241 RALAPARLLVSGSAALPVPVFDGLAALSGHRAIERYGSTETLITLSTFASGERRPGWVGL 300 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PL GV TRLV DDG E+PHDGE++G+L V+ PTLFDGYLN+PDATA D WY TGDV Sbjct 301 PLQGVTTRLVADDGTELPHDGESIGQLHVQSPTLFDGYLNRPDATAEVLGDDGWYHTGDV 360 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D SGMHRIVGRESVDLIKSGG+R+GAGEIETVLL H V EAAV+G PD DLGQRI+ Sbjct 361 AVIDSSGMHRIVGRESVDLIKSGGFRIGAGEIETVLLQHAGVREAAVIGAPDADLGQRII 420 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A+VVG A D LI++VAQQLSVHKRPREVR+V++LPRNA+GK+LKK+L Sbjct 421 AFVVGDAQ--PDELIDYVAQQLSVHKRPREVRVVESLPRNAMGKLLKKEL 468 >gi|54026717|ref|YP_120959.1| acyl-CoA synthetase [Nocardia farcinica IFM 10152] gi|54018225|dbj|BAD59595.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152] Length=479 Score = 639 bits (1649), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/478 (72%), Positives = 380/478 (80%), Gaps = 10/478 (2%) Query 1 VLLASLNPAVVSA-ADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LL+SLNPA V+A ADI AV IDG LSR DL+GAATSVAERVA A RVAVLA PT T Sbjct 7 LLLSSLNPAAVAAGADIPAAVTIDGVTLSRGDLLGAATSVAERVARAERVAVLARPTVRT 66 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+ G L+AGV VVPVP D G E H+L DSG QAWLG PDD LP IPVR HARS Sbjct 67 VLAVVGSLLAGVTVVPVPPDSGAAELAHILADSGAQAWLGDAPDD-TDLPVIPVRVHARS 125 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH YPEP A A V+YTSGTTGPPKGV LSRRAIAA LDALAEAW+WTA D LVHGLPL Sbjct 126 WHTYPEPDSAAPAFVLYTSGTTGPPKGVVLSRRAIAAGLDALAEAWEWTANDTLVHGLPL 185 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGLVLG+LG LR G+ VHTGKPTP YA EA GTL+FGVPTVWSR+ D +A Sbjct 186 FHVHGLVLGVLGPLRVGSPLVHTGKPTPRAYA----EAKGTLYFGVPTVWSRIVEDPESA 241 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL+ ARLLVSGSA LPVPVF++L +LTGH PVERYG SE++ITLSTRADGERRPGWVG+ Sbjct 242 RALRDARLLVSGSAPLPVPVFERLRELTGHAPVERYGMSETMITLSTRADGERRPGWVGV 301 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 P+ GVQTRL D+ G VPHDGE++G LQVRGP LFDGYL +PDATAA++ D W+ TGDV Sbjct 302 PVRGVQTRLRDEAGAPVPHDGESIGGLQVRGPMLFDGYLGRPDATAASWTEDGWFSTGDV 361 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 A +D G HRIVGRESVDLIKSGGYR+GAGE+ET LLGHP VAEAAVVG+ DDDLGQR+V Sbjct 362 AAIDPDGFHRIVGRESVDLIKSGGYRIGAGEVETALLGHPAVAEAAVVGLADDDLGQRVV 421 Query 420 AYVVGSANVDAD----GLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 A+VV A D D LI VA QLSVHKRPREVR+VD+LPRNA+GKV KK L + G Sbjct 422 AFVVARAGHDRDDLPTALIGHVADQLSVHKRPREVRVVDSLPRNAMGKVQKKALAAGG 479 >gi|325676443|ref|ZP_08156121.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] gi|325552621|gb|EGD22305.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] Length=470 Score = 625 bits (1611), Expect = 6e-177, Method: Compositional matrix adjust. Identities = 318/470 (68%), Positives = 380/470 (81%), Gaps = 4/470 (0%) Query 1 VLLASLNP-AVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 VLL+SLNP AV D+ DAVRI LSR+D++GAA ++A+R+AGA VAVLA PT +T Sbjct 4 VLLSSLNPLAVARGDDMPDAVRIGDTALSRTDILGAAGALAKRIAGARVVAVLAEPTPAT 63 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 V+A+ GCL+AGV VVPVP D G E H+L+DSG Q WLG P+ + LP +PVR HAR Sbjct 64 VIAVVGCLLAGVTVVPVPPDSGPAELEHILSDSGAQGWLGRAPEG-STLPVVPVRVHARD 122 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH +PEP P + A V+YTSGTTGPPKGV LSRRAIAA +DALAEAW WT++DVLVHGLPL Sbjct 123 WHSHPEPHPSSTAFVLYTSGTTGPPKGVLLSRRAIAAGIDALAEAWDWTSKDVLVHGLPL 182 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGL+LG+LG LR G+R VHT KPTP YA A A G+LFFGVPTVWSR+ D+A+A Sbjct 183 FHVHGLILGVLGPLRVGSRLVHTVKPTPQAYADAA-RAGGSLFFGVPTVWSRIVEDEASA 241 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF++L LTG P+ERYG SE+++T+STR DGERRPGWVG+ Sbjct 242 RALSGARLLVSGSAPLPVPVFERLRALTGLTPIERYGMSETMLTISTRVDGERRPGWVGV 301 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 P++GV+TRL D+ GGEVPHDGE++G LQVRG TLFDGYLN+PDATA ++ D W++TGDV Sbjct 302 PVSGVETRLRDEHGGEVPHDGESIGGLQVRGATLFDGYLNRPDATAESWTEDGWFKTGDV 361 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES DLIKSGGYR+GAGE+ET LLGHP V EAAVVG+PD DLGQRIV Sbjct 362 AVIDAGGFHRIVGRESTDLIKSGGYRIGAGEVETALLGHPGVKEAAVVGLPDADLGQRIV 421 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A+VVG +D LI+ VA QLSVHKRPREVR+V++LPRNA+GKV KK L Sbjct 422 AFVVGD-ELDEQALIDHVASQLSVHKRPREVRLVESLPRNAMGKVQKKLL 470 >gi|312138854|ref|YP_004006190.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] gi|311888193|emb|CBH47505.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] Length=467 Score = 623 bits (1607), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 318/470 (68%), Positives = 379/470 (81%), Gaps = 4/470 (0%) Query 1 VLLASLNP-AVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LL+SLNP AV D+ DAVRI VLSR+D++GAA ++A+R+AGA VAVLA PT +T Sbjct 1 MLLSSLNPLAVARGDDMPDAVRIGDTVLSRTDILGAAGALAKRIAGARVVAVLAEPTPAT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 V+A+ GCL+AGV VVPVP D G E H+L+DSG Q WLG P+ A LP +PVR HAR Sbjct 61 VIAVVGCLLAGVTVVPVPPDSGPAELEHILSDSGAQGWLGRAPEGSA-LPVVPVRVHARD 119 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH +PEP P + A V+YTSGTTGPPKGV LSRRAIAA +DALAEAW WT++DVLVHGLPL Sbjct 120 WHSHPEPHPSSTAFVLYTSGTTGPPKGVLLSRRAIAAGIDALAEAWDWTSKDVLVHGLPL 179 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGL+LG+LG LR G+R VHT KPTP Y A A G+LFFGVPTVWSR+ D+A+A Sbjct 180 FHVHGLILGVLGPLRVGSRLVHTVKPTPQAYVDAA-RAGGSLFFGVPTVWSRIVEDEASA 238 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF++L LTG P+ERYG SE+++T+STR DGERRPGWVG+ Sbjct 239 RALSGARLLVSGSAPLPVPVFERLRALTGLTPIERYGMSETMLTISTRVDGERRPGWVGV 298 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 P+ GV+TRL D+ GGEVPHDGE++G LQVRG TLFDGYLN+PDATA ++ D W++TGDV Sbjct 299 PVRGVETRLRDEHGGEVPHDGESIGGLQVRGATLFDGYLNRPDATAESWTEDGWFKTGDV 358 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES DLIKSGGYR+GAGE+ET LLGHP V EAAVVG+PD DLGQRIV Sbjct 359 AVIDAGGFHRIVGRESTDLIKSGGYRIGAGEVETALLGHPGVKEAAVVGLPDADLGQRIV 418 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A+VVG +D LI+ VA QLSVHKRPREVR+V++LPRNA+GKV KK L Sbjct 419 AFVVGD-GLDEQALIDHVASQLSVHKRPREVRLVESLPRNAMGKVQKKLL 467 >gi|229493925|ref|ZP_04387697.1| acyl-CoA synthetase [Rhodococcus erythropolis SK121] gi|229319202|gb|EEN85051.1| acyl-CoA synthetase [Rhodococcus erythropolis SK121] Length=471 Score = 622 bits (1603), Expect = 6e-176, Method: Compositional matrix adjust. Identities = 319/474 (68%), Positives = 371/474 (79%), Gaps = 8/474 (1%) Query 1 VLLASLNP-AVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 VLL SLNP AV D+ DAV I VLSRS ++GAATSVAERVA A RVAVLATPTA T Sbjct 2 VLLRSLNPLAVARGEDLDDAVTIGDTVLSRSAILGAATSVAERVAQADRVAVLATPTAKT 61 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 +LA+ G LIAGV VVPVP D G ER H+L DSG QAWLG D GLP +PVR HARS Sbjct 62 ILAVVGALIAGVTVVPVPPDSGKAEREHILRDSGAQAWLGETDDHCEGLPVVPVRLHARS 121 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH YPEP+P + A V+YTSGTTGPPKGV LSR AIAA LDALAEAW WT D LVHGLPL Sbjct 122 WHSYPEPAPQSTAFVLYTSGTTGPPKGVLLSRSAIAAGLDALAEAWDWTWRDTLVHGLPL 181 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGL+LG+LG LR G+R +HT KPTP YA+A G+L+FGVPTVWSR+A D+ AA Sbjct 182 FHVHGLILGILGPLRIGSRVIHTVKPTPENYARA----KGSLYFGVPTVWSRIAEDEEAA 237 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF+KL + TG P+ERYG SE+++TLSTR DGERRPGWVG+ Sbjct 238 RALSGARLLVSGSAPLPVPVFEKLRERTGLTPIERYGMSETMLTLSTRFDGERRPGWVGV 297 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PL GV+TRL D+ G +VPHDGE++G LQVRGP LFDGYLN+PDATA ++ D +++TGDV Sbjct 298 PLRGVETRLRDEKGNDVPHDGESIGGLQVRGPMLFDGYLNRPDATAESWTEDGYFKTGDV 357 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES+DLIKSGG+RVGAGEIET +LGHP V+E AV+GVPD DLGQRI+ Sbjct 358 AVIDEGGFHRIVGRESIDLIKSGGFRVGAGEIETAILGHPSVSEVAVIGVPDADLGQRII 417 Query 420 AYVV---GSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 A VV G+ V L+ V +LS HKRPREVR + LPRNA+GKV K++LL Sbjct 418 AVVVRKPGTPEVTEAELVELVGAELSAHKRPREVRFAETLPRNAMGKVQKRELL 471 >gi|169628425|ref|YP_001702074.1| acyl-CoA synthetase [Mycobacterium abscessus ATCC 19977] gi|169240392|emb|CAM61420.1| Probable fatty-acid-CoA ligase FadD [Mycobacterium abscessus] Length=463 Score = 621 bits (1602), Expect = 7e-176, Method: Compositional matrix adjust. Identities = 332/472 (71%), Positives = 384/472 (82%), Gaps = 10/472 (2%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHR-VAVLATPTAST 59 +LL SL+P + D+ADAVRI D R DLVGAAT+ AER+ GA +AVLA P+ T Sbjct 1 MLLTSLHP---KSPDLADAVRIGEDSWGRGDLVGAATAAAERIGGASGPIAVLARPSIDT 57 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+ LIAGVP+VPVPADVG+ ERRH+L DS AWLG PD+ GLPH+PVR HARS Sbjct 58 VLAVVAGLIAGVPIVPVPADVGIAERRHILADSAAVAWLGESPDESEGLPHVPVRRHARS 117 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH+Y EP+P + A++VYTSGTTG PKGV+LSRRA+AA LD LA+AW+WTA+DVLVHGLPL Sbjct 118 WHQYSEPNPESTALIVYTSGTTGAPKGVRLSRRALAASLDGLADAWEWTADDVLVHGLPL 177 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGLVLGLLGSLR GNRFVHT KPTP YA A G+L+FGVPTVW RVA D++ A Sbjct 178 FHVHGLVLGLLGSLRVGNRFVHTVKPTPEAYAAA----RGSLYFGVPTVWLRVAGDESCA 233 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVFD+L +LTGH P+ERYGA+E++ITLSTRADGERR GWVG Sbjct 234 RALSTARLLVSGSAPLPVPVFDELCRLTGHAPIERYGATETVITLSTRADGERRAGWVGH 293 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PL GV+TRL+ ++G HDGETVG+LQ++GPTLF GY N P+ TA D WYRTGDV Sbjct 294 PLTGVRTRLLAENGSPAAHDGETVGQLQIQGPTLFSGYHNLPEKTAEVLTEDGWYRTGDV 353 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D GMHRIVGRESVDLIKSGGYR+GAGEIETVLLGHP + E AVVGVPDDDLGQRIV Sbjct 354 AVIDAGGMHRIVGRESVDLIKSGGYRIGAGEIETVLLGHPGIVEVAVVGVPDDDLGQRIV 413 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLS 471 AYVVG +V D +I FVAQQLSVHKRPREVR VDALPRNA+GKVLKK+L++ Sbjct 414 AYVVG--DVAEDDVIGFVAQQLSVHKRPREVRRVDALPRNAMGKVLKKELIT 463 >gi|333989812|ref|YP_004522426.1| fatty-acid-CoA synthetase [Mycobacterium sp. JDM601] gi|333485780|gb|AEF35172.1| fatty-acid-CoA synthetase FadD36 [Mycobacterium sp. JDM601] Length=466 Score = 620 bits (1598), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 349/472 (74%), Positives = 393/472 (84%), Gaps = 9/472 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL SL+ V DIADAVRID LSR+DL AA + E + GA RVAVLATPTASTV Sbjct 1 MLLTSLDTHV---DDIADAVRIDNTTLSRADLRAAAAAAHEDLGGAGRVAVLATPTASTV 57 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+ GCL+AG+PVVPVPADVGV ER H+L DS QAWLG P + AGLPH+PVR A S Sbjct 58 LAVAGCLLAGLPVVPVPADVGVVERAHILRDSNAQAWLGERPTELAGLPHVPVRRGAGSA 117 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 PEP+ A+V+YTSGTTGPPKGVQLSRRA+AADLDALA+AWQW+ EDVLVHGLP+Y Sbjct 118 RPTPEPAGDDAALVIYTSGTTGPPKGVQLSRRALAADLDALAQAWQWSPEDVLVHGLPMY 177 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGLVLGLLGSLR GNRFVHTGKPTP YA A GTL+FGVPTVWSRV AD AA Sbjct 178 HVHGLVLGLLGSLRVGNRFVHTGKPTPQAYAAA----RGTLYFGVPTVWSRVVADAGAAE 233 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+PARLLVSGSAALPVPVFD LV TGH+P+ERYG++ESLIT+STR DGERRPGWVGLP Sbjct 234 ALRPARLLVSGSAALPVPVFDALVARTGHQPIERYGSTESLITVSTRVDGERRPGWVGLP 293 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 L GVQT+L+ +DGG VPHDG T+G+L VRGPTLFDGYLN P+ATAAAFDAD WYRTGDVA Sbjct 294 LHGVQTKLIGEDGGPVPHDGATIGRLAVRGPTLFDGYLNLPEATAAAFDADGWYRTGDVA 353 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 V+D GMHRIVGRESVDLIK+GG+RVGAGEIET LLGHP VAE AVVG+PD+DLGQRIVA Sbjct 354 VIDADGMHRIVGRESVDLIKTGGFRVGAGEIETALLGHPAVAEVAVVGLPDEDLGQRIVA 413 Query 421 YVVGSAN--VDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 +VV + + +D LI++V QQLS HKRPREVR+VDALPRNA+GKVLKK LL Sbjct 414 FVVAAPDHTATSDELIDYVGQQLSAHKRPREVRMVDALPRNAMGKVLKKALL 465 >gi|111022917|ref|YP_705889.1| acyl-CoA synthetase [Rhodococcus jostii RHA1] gi|110822447|gb|ABG97731.1| CoA ligase [Rhodococcus jostii RHA1] Length=466 Score = 619 bits (1596), Expect = 4e-175, Method: Compositional matrix adjust. Identities = 325/471 (70%), Positives = 377/471 (81%), Gaps = 6/471 (1%) Query 1 VLLASLNP-AVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LL SLNP AV DI DA+RI LSR D++GAATSVAERVA A RVA+LATPT +T Sbjct 1 MLLRSLNPLAVAQGDDIPDAIRIGDATLSRGDVLGAATSVAERVARADRVAILATPTVTT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+ GCLIAGV VPVP D G E H+L DSG QAWLG P D AGLP +PVR HARS Sbjct 61 VLAVVGCLIAGVTAVPVPPDSGPAELEHILRDSGAQAWLGEAPADTAGLPVVPVRVHARS 120 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH YPEP IA V+YTSGTTGPPKGV +SR+AIAA LDALA+AWQWT D LVHGLPL Sbjct 121 WHSYPEPPESGIAFVLYTSGTTGPPKGVLISRKAIAAGLDALADAWQWTRNDTLVHGLPL 180 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGL+LG+LG LR G+R VHT KPTPA YA A HGT++FGVPTVW R+A D +A Sbjct 181 FHVHGLILGVLGPLRIGSRLVHTVKPTPAAYAAA----HGTMYFGVPTVWGRIADDPESA 236 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF+KL +LTG P+ERYG SE+++TLSTRADGERRPGWVG+ Sbjct 237 RALSGARLLVSGSAPLPVPVFEKLHELTGLAPIERYGMSETMLTLSTRADGERRPGWVGV 296 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 P+ GV+TRL D+ GG+VPHDGE++G LQVRGP LFDGYL +PDATA +F D +++TGDV Sbjct 297 PVRGVETRLRDERGGDVPHDGESIGGLQVRGPMLFDGYLGKPDATAESFTDDGFFKTGDV 356 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES DLIKSGG+RVGAGE+ET LLGHP V EAAVVG+PD DLGQR+V Sbjct 357 AVIDPDGFHRIVGRESTDLIKSGGFRVGAGEVETSLLGHPSVREAAVVGLPDPDLGQRLV 416 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 A+VVG +V LI VA +LSVHKRPRE+R+V++LPRNA+GKV KKQL Sbjct 417 AFVVGD-DVSETELIEHVATELSVHKRPREIRVVESLPRNAMGKVQKKQLF 466 >gi|226365425|ref|YP_002783208.1| acyl-CoA synthetase [Rhodococcus opacus B4] gi|226243915|dbj|BAH54263.1| putative fatty-acid--CoA ligase [Rhodococcus opacus B4] Length=466 Score = 616 bits (1589), Expect = 3e-174, Method: Compositional matrix adjust. Identities = 324/471 (69%), Positives = 377/471 (81%), Gaps = 6/471 (1%) Query 1 VLLASLNP-AVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LL SLNP AV DI DA+RI LSR D++GAATSVAERVA A RVA+LATPTA+T Sbjct 1 MLLRSLNPLAVARGDDIPDAIRIGDTTLSRGDVLGAATSVAERVARADRVAILATPTATT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLA+ GCLIAGV VPVP D G E H+L DSG QAWLG P D AGLP +PVR HARS Sbjct 61 VLAVVGCLIAGVTAVPVPPDSGPAELEHILRDSGAQAWLGEAPADAAGLPVVPVRVHARS 120 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH YPEP A+A V+YTSGTTGPPKGV +SR+AIAA LDALA+AWQWT D LV GLPL Sbjct 121 WHSYPEPPESAVAFVLYTSGTTGPPKGVLISRKAIAAGLDALADAWQWTGNDTLVQGLPL 180 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +H+HGL+LG+LG LR G+R VHT KPTPA YA A GT++FGVPTVWSR+A D +A Sbjct 181 FHIHGLILGVLGPLRIGSRLVHTVKPTPAAYAAA----RGTMYFGVPTVWSRIADDPESA 236 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF+K+ +LTG VERYG SE+++TLSTRADGERRPGWVG+ Sbjct 237 RALSGARLLVSGSAPLPVPVFEKVQELTGLALVERYGMSETMLTLSTRADGERRPGWVGV 296 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PL GV+TRL D+ GG+VPHDGE++G LQVRGP LFDGYL +PDATA +F D +++TGDV Sbjct 297 PLRGVETRLRDERGGDVPHDGESIGGLQVRGPMLFDGYLGRPDATAESFTDDGFFKTGDV 356 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES DLIKSGG+RVGAGE+ET LLGHP V EAAVVG+PD DLGQR+V Sbjct 357 AVIDPGGFHRIVGRESTDLIKSGGFRVGAGEVETSLLGHPSVREAAVVGIPDPDLGQRLV 416 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 A+VVG +V LI VA +LSVHKRPRE+R+V++LPRNA+GKV KKQL Sbjct 417 AFVVGD-DVSETALIEHVATELSVHKRPREIRVVESLPRNAMGKVQKKQLF 466 >gi|226307665|ref|YP_002767625.1| fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] gi|226186782|dbj|BAH34886.1| putative fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] Length=471 Score = 610 bits (1574), Expect = 1e-172, Method: Compositional matrix adjust. Identities = 315/474 (67%), Positives = 367/474 (78%), Gaps = 8/474 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGD-VLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 VLL SLNP V+ D DA GD VLSRS ++GAATSVAERVA A RVAVLATPTA T Sbjct 2 VLLRSLNPLAVARGDDLDAAVTIGDTVLSRSAILGAATSVAERVAQADRVAVLATPTAKT 61 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 +LA+ G LIAGV VVPVP D G ER H+L DSG QAWLG D LP +PVR HARS Sbjct 62 ILAVVGALIAGVTVVPVPPDSGKAEREHILRDSGAQAWLGETDDHCDTLPVVPVRLHARS 121 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WH YPEP+P + A V+YTSGTTGPPKGV LSR AIAA +DALAEAW WT D LVHGLPL Sbjct 122 WHSYPEPAPQSTAFVLYTSGTTGPPKGVLLSRSAIAAGIDALAEAWDWTWRDTLVHGLPL 181 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 +HVHGL+LG+LG LR G+R +HT KPTP YA+A G+L+FGVPTVWSR+A D+ AA Sbjct 182 FHVHGLILGILGPLRIGSRVIHTVKPTPENYARA----KGSLYFGVPTVWSRIAEDEEAA 237 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVF+KL TG P+ERYG SE+++TLSTR DGERRPGWVG+ Sbjct 238 RALSGARLLVSGSAPLPVPVFEKLRDRTGLTPIERYGMSETMLTLSTRFDGERRPGWVGV 297 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PL GV+TRL D+ G +VPHDGE++G LQVRGP LFDGYLN+PDATA ++ D +++TGDV Sbjct 298 PLRGVETRLRDEKGNDVPHDGESIGGLQVRGPMLFDGYLNRPDATAESWTEDGYFKTGDV 357 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AV+D G HRIVGRES+DLIK+GG+RVGAGEIET +LGHP V+E AV+GVPD DLGQRI+ Sbjct 358 AVIDEGGFHRIVGRESIDLIKTGGFRVGAGEIETAILGHPSVSEVAVIGVPDADLGQRII 417 Query 420 AYVV---GSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 A VV GS V L+ V +LS HKRPREVR + LPRNA+GKV K++L Sbjct 418 AVVVRKPGSPEVAEAELVELVGGELSAHKRPREVRFAETLPRNAMGKVQKRELF 471 >gi|108800984|ref|YP_641181.1| acyl-CoA synthetase [Mycobacterium sp. MCS] gi|119870125|ref|YP_940077.1| acyl-CoA synthetase [Mycobacterium sp. KMS] gi|126436821|ref|YP_001072512.1| acyl-CoA synthetase [Mycobacterium sp. JLS] gi|108771403|gb|ABG10125.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119696214|gb|ABL93287.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] gi|126236621|gb|ABO00022.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=467 Score = 599 bits (1544), Expect = 4e-169, Method: Compositional matrix adjust. Identities = 370/470 (79%), Positives = 403/470 (86%), Gaps = 8/470 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGD-VLSRSDLVGAATSVAERVAGAHRVAVLATPTAST 59 +LL SLNPA V+A G+ VLSRSDLVGAATSVAERV GA RVAVLATPT +T Sbjct 1 MLLTSLNPAAVAAGADIADAVTIGEAVLSRSDLVGAATSVAERVGGAQRVAVLATPTPAT 60 Query 60 VLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARS 119 VLAITGCLIAGVPVVPVPADVGV ERRH+LTDSG QAWLG P+D LPHIPVR HARS Sbjct 61 VLAITGCLIAGVPVVPVPADVGVAERRHILTDSGAQAWLGDKPEDTE-LPHIPVRLHARS 119 Query 120 WHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPL 179 WHRY EP P + A++VYTSGTTGPPKGV +SRRAIAADLDALAEAWQWTAED LVHGLPL Sbjct 120 WHRYAEPHPDSAALIVYTSGTTGPPKGVVISRRAIAADLDALAEAWQWTAEDTLVHGLPL 179 Query 180 YHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAA 239 YHVHGLVLGLLGSLR GNRFVHTG+PTP YAQA GTL+FGVPTVWSR+AAD AA Sbjct 180 YHVHGLVLGLLGSLRIGNRFVHTGRPTPEAYAQA----QGTLYFGVPTVWSRIAADDDAA 235 Query 240 GALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGL 299 AL ARLLVSGSA LPVPVFD+L TGH VERYG++ESLITLSTRADGERRPGWVGL Sbjct 236 RALATARLLVSGSAPLPVPVFDRLAASTGHEVVERYGSTESLITLSTRADGERRPGWVGL 295 Query 300 PLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDV 359 PLAGV+TRLV DDG VPHDGET+ +L+VRGPTLFDGYLN+PDATA D WYRTGDV Sbjct 296 PLAGVETRLVGDDGAPVPHDGETIARLEVRGPTLFDGYLNRPDATADVLGVDGWYRTGDV 355 Query 360 AVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIV 419 AVVDG GMHRIVGRESVDLIK+GG+RVGAGEIETVLLGH VAEAAVVG+PDDDLGQRIV Sbjct 356 AVVDGVGMHRIVGRESVDLIKTGGFRVGAGEIETVLLGHDGVAEAAVVGMPDDDLGQRIV 415 Query 420 AYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A+VVG A +A LI++VA+QLSVHKRPREVR+VD+LPRNA+GKVLKK+L Sbjct 416 AFVVGDATPEA--LIDYVAEQLSVHKRPREVRMVDSLPRNAMGKVLKKEL 463 >gi|262204578|ref|YP_003275786.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] gi|262087925|gb|ACY23893.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] Length=468 Score = 573 bits (1478), Expect = 2e-161, Method: Compositional matrix adjust. Identities = 311/472 (66%), Positives = 359/472 (77%), Gaps = 9/472 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL +L P +A D++DAV I D LSR DL+GAAT+VAER+ GAH VAVLA PT TV Sbjct 2 LLLPTLLP---NAPDLSDAVVIGDDHLSREDLIGAATAVAERIRGAHTVAVLARPTVDTV 58 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPD---DPAGLPHIPVRTHA 117 LA+ G LIAGV VVPVP D G E H+L DSG QAWLGP PD D GLP IPVR +A Sbjct 59 LAVVGGLIAGVAVVPVPPDSGPRELEHILADSGAQAWLGPAPDGASDQPGLPSIPVRRYA 118 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 RSWH +PEP + A+++YTSGTTG PKGV ++RRAIAA LDAL EAW W++ D L HGL Sbjct 119 RSWHSHPEPPADSTALILYTSGTTGLPKGVPITRRAIAAGLDALGEAWLWSSGDTLAHGL 178 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PL+HVHGL+LG+LG LR G R +HT KPTP GYA A T+FFGVPTVW RVAAD A Sbjct 179 PLFHVHGLILGVLGPLRRGGRLIHTVKPTPDGYAAAADAGA-TMFFGVPTVWHRVAADTA 237 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 AA L ARLLVSGSA LPVPVF+++ +GH VERYG +E+LIT+STRADGERRPGWV Sbjct 238 AAQRLSGARLLVSGSAPLPVPVFEQIRAHSGHEIVERYGMTETLITVSTRADGERRPGWV 297 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPL GV+TRL + +VPHDGE+VG L VRGP L GYLN+PDATA + D W+ TG Sbjct 298 GLPLLGVETRL-REGTEDVPHDGESVGDLHVRGPMLSTGYLNRPDATAECYLDDGWFATG 356 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAV+ GMHRIVGR S DLIKSGGYR+GAGEIETVL+ HP V E AV+GVPDDDLGQR Sbjct 357 DVAVIGADGMHRIVGRRSTDLIKSGGYRIGAGEIETVLMAHPSVREVAVIGVPDDDLGQR 416 Query 418 IVAYVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 IVAYVVG VD LI+ VA +LS HKRPRE+R +D LPRNA+GKV KK L Sbjct 417 IVAYVVGE-RVDDQVLIDLVASELSHHKRPREIRFLDELPRNAMGKVQKKML 467 >gi|296139000|ref|YP_003646243.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] gi|296027134|gb|ADG77904.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] Length=472 Score = 566 bits (1458), Expect = 3e-159, Method: Compositional matrix adjust. Identities = 301/476 (64%), Positives = 352/476 (74%), Gaps = 10/476 (2%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAG---AHRVAVLATPTA 57 +LL V +D AV + G LSR+DL+GA+T+VAER+ G VAV A PT Sbjct 1 MLLPHTVTPVPPGSDDEPAVTVGGRTLSRTDLIGASTAVAERLRGLGVRGPVAVWAEPTV 60 Query 58 STVLAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHA 117 +TV+A G L AGVP VPVP D G E H+L D+GVQAWLG PDDP GLP +PVR HA Sbjct 61 ATVIAFVGALRAGVPAVPVPPDSGSAEVAHVLADAGVQAWLGVTPDDPQGLPAVPVREHA 120 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 R WH PEP AIA+++YTSGTTG PKGV + R AIAA LD LA+AW WTA D LVHGL Sbjct 121 RGWHALPEPPASAIALIMYTSGTTGAPKGVPIRRGAIAACLDGLAQAWGWTANDTLVHGL 180 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PL+HVHGL+LG+LG+LR G+ VHTGKPTP YA A GTL+FGVPTVWSR+A D Sbjct 181 PLFHVHGLILGVLGALRAGSPLVHTGKPTPEAYAAA----RGTLYFGVPTVWSRIARDPE 236 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 +A ALK ARLLVSGSA LP PVFD++ LTGH VERYG +E+LIT+S RADG+RRPGWV Sbjct 237 SAAALKDARLLVSGSAPLPAPVFDRIRDLTGHEIVERYGMTETLITVSARADGDRRPGWV 296 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 GLPLAGV+TRLV D G VPHDGE+VG LQVRGP + YL +PDATA ++ + W+ TG Sbjct 297 GLPLAGVETRLVSDTGEAVPHDGESVGALQVRGPMVGTEYLGRPDATAESWVGEGWFDTG 356 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 DVAV+D +G HRIVGR S DLIK+GG+RVGAGEIE LLGH DV EAAVVG+PDDDLGQR Sbjct 357 DVAVIDPTGFHRIVGRASTDLIKTGGFRVGAGEIEAALLGHDDVREAAVVGLPDDDLGQR 416 Query 418 IVAYVVGSANVD---ADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 +VA+VV D A ++ FV Q LS HKRPRE+R VD LPRN +GKV KK LL Sbjct 417 VVAFVVADGARDDSAAVAIVEFVGQTLSKHKRPREIRFVDQLPRNPMGKVQKKLLL 472 >gi|325677455|ref|ZP_08157119.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] gi|325551702|gb|EGD21400.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] Length=477 Score = 563 bits (1451), Expect = 2e-158, Method: Compositional matrix adjust. Identities = 285/454 (63%), Positives = 343/454 (76%), Gaps = 6/454 (1%) Query 19 AVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVPA 78 AVR+ L+RSDL+ A +VA+ ++GA VA+ AT T TV+A+TGCL+AGVP VPVP Sbjct 25 AVRVGDGALTRSDLIAAGAAVADEISGATSVAIDATATLETVIAVTGCLMAGVPAVPVPP 84 Query 79 DVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMVVYTS 138 D G ER H+L DSG Q WLG +D LPH+P+ ARS Y EP PG AM++YTS Sbjct 85 DSGPAERDHILKDSGAQLWLGGRRED-VTLPHVPIHARARSGSTYAEPDPGTTAMIMYTS 143 Query 139 GTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLRFGNR 198 GTTG PKGV L+R AIAA LD LAEAW W+ +D LVHGLPL+HVHGL+LG++G+LR G+ Sbjct 144 GTTGAPKGVVLARSAIAAGLDGLAEAWDWSPDDTLVHGLPLFHVHGLILGVVGALRHGSP 203 Query 199 FVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAALPVP 258 VHT +PTP YA A G+L+FGVPTVWSRV AD++AA L ARLLVSGSA LPVP Sbjct 204 LVHTVRPTPESYAAAG----GSLYFGVPTVWSRVCADESAARTLGAARLLVSGSAPLPVP 259 Query 259 VFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGGEVPH 318 +F+++ LTG P+ERYG SE+LITLSTR DGERRPGWVGLP+ GV RL D G V H Sbjct 260 IFERMQALTGSAPIERYGMSETLITLSTRFDGERRPGWVGLPIRGVAARLRDQAGNPVAH 319 Query 319 DGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGRESVDL 378 DGET+G+L++ G TLFDGYL D TA + D W++TGD+AVVD G HRIVGRES+D+ Sbjct 320 DGETLGQLEIAGATLFDGYLGNFDKTAESMTDDGWFKTGDIAVVDEQGFHRIVGRESIDM 379 Query 379 IKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGLINFVA 438 IKSGGYR+GAGE+E LL HP V EAAVVGVPDDDLGQRIVA++VG N D L NFVA Sbjct 380 IKSGGYRIGAGEVEQALLAHPGVKEAAVVGVPDDDLGQRIVAFIVGDCN-DHRELSNFVA 438 Query 439 QQLSVHKRPREVRIVDALPRNALGKVLKKQLLSE 472 Q LS+HKRPRE+R+VD LPRNA+GKV KK L+ + Sbjct 439 QTLSIHKRPREIRVVDVLPRNAMGKVQKKLLVDD 472 >gi|312137574|ref|YP_004004910.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] gi|311886913|emb|CBH46222.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] Length=477 Score = 563 bits (1451), Expect = 2e-158, Method: Compositional matrix adjust. Identities = 286/454 (63%), Positives = 343/454 (76%), Gaps = 6/454 (1%) Query 19 AVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVPA 78 AVR+ L+RSDL+ A +VA+ ++GA VA+ AT T TV+A+TGCL+AGVP VPVP Sbjct 25 AVRVGDGALTRSDLIAAGAAVADEISGATSVAIDATATLETVIAVTGCLMAGVPAVPVPP 84 Query 79 DVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMVVYTS 138 D G ER H+L DSG Q WLG +D LPH+P+ ARS Y EP PG AM++YTS Sbjct 85 DSGPAERDHILKDSGAQLWLGGRRED-VTLPHVPIHARARSGSTYAEPDPGTTAMIMYTS 143 Query 139 GTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLRFGNR 198 GTTG PKGV L+R AIAA LD LAEAW W+ +D LVHGLPL+HVHGL+LG++G+LR G+ Sbjct 144 GTTGAPKGVVLARSAIAAGLDGLAEAWDWSPDDTLVHGLPLFHVHGLILGVVGALRHGSP 203 Query 199 FVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAALPVP 258 VHT +PTP YA A G+L+FGVPTVWSRV AD++AA L ARLLVSGSA LPVP Sbjct 204 LVHTVRPTPESYAAAG----GSLYFGVPTVWSRVCADESAARTLGSARLLVSGSAPLPVP 259 Query 259 VFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGGEVPH 318 VF+++ LTG P+ERYG SE+LITLSTR DGERRPGWVGLP+ GV RL D G V H Sbjct 260 VFERMQALTGSAPIERYGMSETLITLSTRFDGERRPGWVGLPIRGVAARLRDQAGNPVAH 319 Query 319 DGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGRESVDL 378 DGET+G+L++ G TLFDGYL D TA + D W++TGD+AVVD G HRIVGRES+D+ Sbjct 320 DGETLGQLEIAGATLFDGYLGNFDKTAESMTDDGWFKTGDIAVVDEQGFHRIVGRESIDM 379 Query 379 IKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGLINFVA 438 IKSGGYR+GAGE+E LL HP V EAAVVGVPDDDLGQRIVA++VG N D L NFVA Sbjct 380 IKSGGYRIGAGEVEQALLAHPGVKEAAVVGVPDDDLGQRIVAFIVGDCN-DHRELSNFVA 438 Query 439 QQLSVHKRPREVRIVDALPRNALGKVLKKQLLSE 472 Q LS+HKRPRE+R+VD LPRNA+GKV KK L+ + Sbjct 439 QTLSIHKRPREIRVVDVLPRNAMGKVQKKLLVDD 472 >gi|333921022|ref|YP_004494603.1| putative acyl-CoA synthetase [Amycolicicoccus subflavus DQS3-9A1] gi|333483243|gb|AEF41803.1| Putative acyl-CoA synthetase [Amycolicicoccus subflavus DQS3-9A1] Length=469 Score = 555 bits (1429), Expect = 8e-156, Method: Compositional matrix adjust. Identities = 307/474 (65%), Positives = 364/474 (77%), Gaps = 11/474 (2%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL SL+ A +S D + A I G+ L+R +L+GAAT+ A RV GA VAVLATPTA TV Sbjct 1 MLLTSLHDAAISD-DTSPAFTIGGESLTRQELIGAATAAAARVQGAAAVAVLATPTAKTV 59 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPH---IPVRTHA 117 +++TG L+AGVPVVPVP D G E H+L DSG QAWLG PD P G+P IPVR HA Sbjct 60 VSVTGALLAGVPVVPVPPDSGPGEVSHILRDSGAQAWLGSAPDLP-GIPKLHAIPVRIHA 118 Query 118 RSWHRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGL 177 R WH+ EP A ++YTSGTTGPPKG +SR AIAA LDALAEAW WTAED LVHGL Sbjct 119 RDWHQLLEPPRDTPAFIMYTSGTTGPPKGAVISRGAIAAGLDALAEAWAWTAEDTLVHGL 178 Query 178 PLYHVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQA 237 PL+HVHGLVLG+LG LR G+R VHTGKP+P YA A G+L+FGVPTVWSR+AAD + Sbjct 179 PLFHVHGLVLGMLGPLRTGSRLVHTGKPSPESYASA----KGSLYFGVPTVWSRIAADPS 234 Query 238 AAGALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWV 297 AA L ARLLVSGSA L PVF+ + L+GH+ VERYG +E+LIT+S RADGERRPGWV Sbjct 235 AAKQLSGARLLVSGSAGLSAPVFESMKSLSGHQLVERYGMTETLITVSARADGERRPGWV 294 Query 298 GLPLAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTG 357 G PL GV TR+V +DGGEV HDGE++G+L VRGP +F GY QP+ TAAAF D W+RTG Sbjct 295 GRPLRGVNTRIVGEDGGEVSHDGESIGQLHVRGPMMFSGYTGQPEVTAAAFAEDGWFRTG 354 Query 358 DVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQR 417 D+A +D SG HRIVGRES DLIKSGGYR+GAGE+E+ LL HP + EAAV+GV DDDLGQ+ Sbjct 355 DIAAIDESGFHRIVGRESTDLIKSGGYRIGAGEVESALLAHPGITEAAVIGVADDDLGQK 414 Query 418 IVAYVVGSANVDADG--LINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 +VAYVVG + DG +I FVA+ LS HKRPREVR+VDALPRNA+GKV K+QL Sbjct 415 LVAYVVGDLDRSDDGAAVIEFVAKYLSAHKRPREVRVVDALPRNAMGKVQKRQL 468 >gi|343928640|ref|ZP_08768085.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] gi|343761389|dbj|GAA15011.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] Length=463 Score = 546 bits (1407), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 305/469 (66%), Positives = 358/469 (77%), Gaps = 7/469 (1%) Query 1 VLLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 +LL +L P +A D + +RI D LSR DLVGAAT+VAER+AGA VAVLA PT TV Sbjct 1 MLLPTLTP---TAPDDPEVIRIGEDRLSREDLVGAATAVAERIAGARTVAVLAQPTVETV 57 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 LA+ G LIAGVPVVPVP D G E H+L DSG QAWLG P D A LP +PVR +A+SW Sbjct 58 LAVVGGLIAGVPVVPVPPDSGPREFAHILADSGAQAWLGQGPAD-ATLPVVPVRRYAKSW 116 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 HR+PEP + A+ +YTSGTTG PKGV ++R+AIA LDALA+AW WTA+D L HGLPL+ Sbjct 117 HRHPEPHADSTALTLYTSGTTGLPKGVPITRQAIAEGLDALADAWLWTADDTLAHGLPLF 176 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGL+LG+LG LR G R +HT KPT A + EA ++FFGVPTVWSRV AD AA Sbjct 177 HVHGLILGVLGPLRRGGRLIHTEKPT-AAGYASAAEAGASMFFGVPTVWSRVGADPEAAR 235 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 L AR+LVSGSA LPVPVFD++ +LTGH VERYG +E+LIT+STR DGERRPGWVGLP Sbjct 236 TLSSARILVSGSAPLPVPVFDRVRELTGHEIVERYGMTETLITVSTRVDGERRPGWVGLP 295 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 LAGV+TRL + D +VPHDGE+VG L VRGP + GYLN+ DATA ++ D ++ TGDVA Sbjct 296 LAGVETRLREGDA-DVPHDGESVGDLHVRGPMMASGYLNRADATAESWLDDGFFATGDVA 354 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 V+D GMHRIVGR S DLIKSGG+R+GAGEIETVLL HP V E AV+GVPDD LGQRIVA Sbjct 355 VIDPDGMHRIVGRRSTDLIKSGGFRIGAGEIETVLLAHPAVRETAVIGVPDDYLGQRIVA 414 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 YVV VD LI FVA +LS HKRPRE+R VD+LPRNA+GKV KK L Sbjct 415 YVVAD-EVDDTELIEFVAGELSNHKRPREIRFVDSLPRNAMGKVQKKLL 462 >gi|302866959|ref|YP_003835596.1| AMP-dependent synthetase and ligase [Micromonospora aurantiaca ATCC 27029] gi|302569818|gb|ADL46020.1| AMP-dependent synthetase and ligase [Micromonospora aurantiaca ATCC 27029] Length=470 Score = 516 bits (1328), Expect = 4e-144, Method: Compositional matrix adjust. Identities = 282/460 (62%), Positives = 334/460 (73%), Gaps = 9/460 (1%) Query 18 DAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVP 77 DA+R+DG +S +L AT+VA+ + G RVA+ AT T TV+ + G L AG VVP+P Sbjct 16 DAIRVDGRAVSWVELRRLATAVADELRGVDRVAIEATATLETVVGVVGALTAGAAVVPIP 75 Query 78 ADVGVTERRHMLTDSGVQAWLGPLPDD----PAGLPHIPVRTHARSWHRYPEPSPGAIAM 133 D G ER H+L DSG A L P + AG P +PV RS +PEP P A+ Sbjct 76 PDAGPMERDHILRDSGATALLAPAGAERTVGDAGRPVVPVDLTRRSDTVHPEPDPACTAV 135 Query 134 VVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSL 193 ++YTSGTTG PKG +SRRAIAA LD LA+AW WT +D+LVHGLPL+HVHGLVLG+LG L Sbjct 136 ILYTSGTTGAPKGAVISRRAIAACLDGLADAWAWTPDDLLVHGLPLFHVHGLVLGVLGPL 195 Query 194 RFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSA 253 R G R H G+P P YA A +GT++FGVPTVWSR+AAD AA AL+PARLLVSGSA Sbjct 196 RLGGRLHHVGRPRPDRYAAA----NGTMYFGVPTVWSRIAADPDAARALRPARLLVSGSA 251 Query 254 ALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDG 313 ALP VF L LTGHR VERYG +E+LIT+S R DG RRPG VGL L GV+TRLV DDG Sbjct 252 ALPAAVFADLATLTGHRVVERYGMTETLITVSARTDGPRRPGTVGLALPGVRTRLVGDDG 311 Query 314 GEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGR 373 +P DG T+G+LQV GPTLFDGYLN+PDA AA+ D W+RTGDVA VD G HRIVGR Sbjct 312 TPLPADGATMGELQVTGPTLFDGYLNRPDADAASRTPDGWFRTGDVATVDPDGWHRIVGR 371 Query 374 ESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGL 433 S DLIKSGGYR+GAGE+E LL HP V EAAVVG P DLGQ++ AYVVG +A+ L Sbjct 372 ASTDLIKSGGYRIGAGEVEDALLTHPGVREAAVVGTPHPDLGQQVTAYVVGDGVGEAE-L 430 Query 434 INFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 I+FVA+ LS HKRPREVR+VDALPRNALGKV K +L ++G Sbjct 431 IDFVARHLSAHKRPREVRLVDALPRNALGKVQKTRLSADG 470 >gi|315506603|ref|YP_004085490.1| amp-dependent synthetase and ligase [Micromonospora sp. L5] gi|315413222|gb|ADU11339.1| AMP-dependent synthetase and ligase [Micromonospora sp. L5] Length=470 Score = 515 bits (1326), Expect = 8e-144, Method: Compositional matrix adjust. Identities = 282/460 (62%), Positives = 333/460 (73%), Gaps = 9/460 (1%) Query 18 DAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVP 77 DA+R+DG S +L AT+VA+ + G RVA+ AT T TV+ + G L AG VVP+P Sbjct 16 DAIRVDGRAASWVELRRLATAVADELRGVDRVAIEATATLETVVGVVGALTAGAAVVPIP 75 Query 78 ADVGVTERRHMLTDSGVQAWLGPLPDD----PAGLPHIPVRTHARSWHRYPEPSPGAIAM 133 D G ER H+L DSG A L P + AG P +PV RS +PEP P A+ Sbjct 76 PDAGPMERDHILRDSGATALLAPAGAEHTVGDAGRPVVPVDLTRRSDTVHPEPDPACTAV 135 Query 134 VVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSL 193 ++YTSGTTG PKG +SRRAIAA LD LA+AW WT +D+LVHGLPL+HVHGLVLG+LG L Sbjct 136 ILYTSGTTGAPKGAVISRRAIAACLDGLADAWAWTPDDLLVHGLPLFHVHGLVLGVLGPL 195 Query 194 RFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSA 253 R G R H G+P P YA A +GT++FGVPTVWSR+AAD AA AL+PARLLVSGSA Sbjct 196 RLGGRLHHVGRPRPDRYAAA----NGTMYFGVPTVWSRIAADPDAARALRPARLLVSGSA 251 Query 254 ALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDG 313 ALP VF L LTGHR VERYG +E+LIT+S R DG RRPG VGL L GV+TRLV DDG Sbjct 252 ALPAAVFADLATLTGHRVVERYGMTETLITVSARTDGPRRPGTVGLALPGVRTRLVGDDG 311 Query 314 GEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGR 373 +P DG T+G+LQV GPTLFDGYLN+PDA AA+ D W+RTGDVA VD G HRIVGR Sbjct 312 TPLPADGTTMGELQVTGPTLFDGYLNRPDADAASRTPDGWFRTGDVATVDPDGWHRIVGR 371 Query 374 ESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGL 433 S DLIKSGGYR+GAGE+E LL HP V EAAVVG P DLGQ++ AYVVG +A+ L Sbjct 372 ASTDLIKSGGYRIGAGEVEDALLTHPGVREAAVVGTPHPDLGQQVTAYVVGDGVGEAE-L 430 Query 434 INFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 I+FVA+ LS HKRPREVR+VDALPRNALGKV K +L ++G Sbjct 431 IDFVARHLSAHKRPREVRLVDALPRNALGKVQKTRLSADG 470 >gi|312200234|ref|YP_004020295.1| AMP-dependent synthetase and ligase [Frankia sp. EuI1c] gi|311231570|gb|ADP84425.1| AMP-dependent synthetase and ligase [Frankia sp. EuI1c] Length=499 Score = 501 bits (1291), Expect = 8e-140, Method: Compositional matrix adjust. Identities = 287/476 (61%), Positives = 338/476 (72%), Gaps = 28/476 (5%) Query 19 AVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVPA 78 AVR+ L R +L AAT+VA+ VAGA VAV + + TV+ I GCL+AGVPVVPVPA Sbjct 24 AVRLADAALRRDELWAAATAVADEVAGAAVVAVHGSASLRTVVGIVGCLLAGVPVVPVPA 83 Query 79 DVGVTERRHMLTDSGVQAWLGPLP-------DDPAGLPHIPVRTHARSWHRYPEPSPGAI 131 D G ER H+L DS + WLG P + L +P+ RS YPEP P Sbjct 84 DAGPRERAHILADSRAELWLGDPPANGDRLDEGSRALTVVPIDPARRSDTSYPEPDPSTT 143 Query 132 AMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLG 191 AM++YTSGTTG PKGV +SRRAIA+ LD LA AW WTA+DVLVHGLPL+HVHGLVLG+LG Sbjct 144 AMIMYTSGTTGAPKGVVISRRAIASCLDGLANAWAWTADDVLVHGLPLFHVHGLVLGVLG 203 Query 192 SLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSG 251 +LR G+ VHTG+P PA YA A G+LFFGVPTVWSR+ + AAA +L ARLLVSG Sbjct 204 ALRVGSPLVHTGRPRPAEYATAAERHGGSLFFGVPTVWSRMCDEPAAAASLGQARLLVSG 263 Query 252 SAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRL--- 308 SA LPVPV ++L LTG PVERYG +ESLIT++ R+DGERRPGWVGL L GV+TRL Sbjct 264 SAPLPVPVAERLRGLTGLVPVERYGMTESLITVAVRSDGERRPGWVGLSLPGVETRLRPL 323 Query 309 -------------VDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYR 355 D D VP DGE+VG+LQVRG +LFDGYL + TAA++ D W+R Sbjct 324 PDASDTPAATSPAADKD---VPWDGESVGELQVRGGSLFDGYLGLAEVTAASWTPDGWFR 380 Query 356 TGDVAVVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLG 415 TGD AV+D +G HRIVGR SVDLIKSGGYR+GAGE+E LL HP + EAAVVGVPD DLG Sbjct 381 TGDAAVIDPAGWHRIVGRTSVDLIKSGGYRIGAGEVEAALLAHPTIVEAAVVGVPDPDLG 440 Query 416 QRIVAYVVGSAN--VDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 QRIVAYVVG VD + +FVA QLSVHKRPREVR+V+ LPRNA+GKV KK L Sbjct 441 QRIVAYVVGDGTTPVDPATVADFVATQLSVHKRPREVRVVEDLPRNAMGKVQKKLL 496 >gi|229494260|ref|ZP_04388023.1| acyl-CoA synthetase family member 3 [Rhodococcus erythropolis SK121] gi|229318622|gb|EEN84480.1| acyl-CoA synthetase family member 3 [Rhodococcus erythropolis SK121] Length=469 Score = 499 bits (1284), Expect = 6e-139, Method: Compositional matrix adjust. Identities = 280/469 (60%), Positives = 345/469 (74%), Gaps = 9/469 (1%) Query 2 LLASLNPAVVSAADIADAVRI-DGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTV 60 LL SL+P + + D AV +G LSR+DL AAT+VA+++ GA RVAV A TV Sbjct 7 LLRSLDPRI--SDDHGAAVSFGEGATLSRADLFAAATAVADQIHGAQRVAVQAAAGLETV 64 Query 61 LAITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSW 120 +A+ G LIAGV VVP+P D G ER+H++ DS + LG P D + +P IP+ HARS Sbjct 65 VAVAGALIAGVAVVPIPPDSGPLERQHIIADSKAELILGEGPTD-SSIPLIPIDIHARSA 123 Query 121 HRYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLY 180 YPEPS A A+++YTSGTTG PKGV LSR +IAADLDALA W WT ED LVHGLPL+ Sbjct 124 TSYPEPSAAATALIMYTSGTTGAPKGVVLSRASIAADLDALAHVWNWTPEDTLVHGLPLF 183 Query 181 HVHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAG 240 HVHGL+LG+LG+LR G+ +HT +PTP YA A G+L+FGVPTVWSRV D +AA Sbjct 184 HVHGLILGVLGALRVGSPLIHTVRPTPDSYAAAG----GSLYFGVPTVWSRVCGDPSAAA 239 Query 241 ALKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLP 300 AL+ ARLLVSGSA LPVP+F+++ LTG PVERYG SE+LIT+ST DGERRPGWVG Sbjct 240 ALRSARLLVSGSAPLPVPLFERMKSLTGLAPVERYGMSETLITVSTTHDGERRPGWVGHS 299 Query 301 LAGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVA 360 + GV+TRL ++G HDGE +G+L+V G LFD YL P TA + D W+RTGD+A Sbjct 300 VPGVRTRLRGENGELSAHDGEQLGQLEVAGAVLFDEYLGNPSKTAESMTEDGWFRTGDIA 359 Query 361 VVDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVA 420 V+D SG HRIVGRESVD+IKSGGYR+GAGE+E LL +P V EAAVVGVPDDDLGQRIVA Sbjct 360 VIDDSGFHRIVGRESVDMIKSGGYRIGAGEVEQALLAYPGVREAAVVGVPDDDLGQRIVA 419 Query 421 YVVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 ++VG D + +FVA+ LS+HKRPR+V +VD+LPRNA+GKV KK L Sbjct 420 FIVGDV-ADCAVVSDFVAESLSIHKRPRQVCLVDSLPRNAMGKVQKKLL 467 >gi|238063671|ref|ZP_04608380.1| acyl-CoA synthetase [Micromonospora sp. ATCC 39149] gi|237885482|gb|EEP74310.1| acyl-CoA synthetase [Micromonospora sp. ATCC 39149] Length=468 Score = 494 bits (1273), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 276/464 (60%), Positives = 328/464 (71%), Gaps = 8/464 (1%) Query 12 SAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGV 71 SA D DA+R+D +S +L AT+VA+ + G RVAV ATPT TV+ + G L+AG Sbjct 10 SADDRPDAIRVDDRAVSWVELRRLATAVADDLVGVDRVAVEATPTLETVVGVVGALLAGA 69 Query 72 PVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPH---IPVRTHARSWHRYPEPSP 128 VVPVP D G ER H+L DSG A L P D +PV RS +PEP P Sbjct 70 AVVPVPPDAGPMERDHILRDSGAAALLVPAGGDGPTDGGPPVVPVDLARRSDTVHPEPDP 129 Query 129 GAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLG 188 A A+++YTSGTTG PKG + R A+AA LD LA+AW WT D+LVHGLPL+HVHGLVLG Sbjct 130 AATALILYTSGTTGAPKGAVIPRGAVAACLDGLADAWAWTPADLLVHGLPLFHVHGLVLG 189 Query 189 LLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLL 248 +LG LR G+R H G+P P YA A GT++FGVPTVWSR+AAD +A AL+PARLL Sbjct 190 VLGPLRLGSRLHHVGRPRPERYAAAG----GTVYFGVPTVWSRIAADPDSARALRPARLL 245 Query 249 VSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRL 308 VSGSAALP VF L LTGH VERYG +E+LIT+S RADG RRPG VG+PL GV+TRL Sbjct 246 VSGSAALPAAVFADLAALTGHEIVERYGMTETLITVSARADGPRRPGTVGVPLPGVRTRL 305 Query 309 VDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMH 368 VD+ G +P DG +G+LQV GPTL DGYLN+PDA AA D W+RTGDVA V G H Sbjct 306 VDEHGAALPADGVAMGELQVAGPTLCDGYLNRPDADAATRTPDGWFRTGDVATVAPDGWH 365 Query 369 RIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANV 428 RIVGR + DLIKSGGYR+GAGE+E LL HP V EAAVVG P DLGQ++ AYVVG V Sbjct 366 RIVGRAATDLIKSGGYRIGAGEVEDALLAHPGVREAAVVGTPHPDLGQQVTAYVVGD-GV 424 Query 429 DADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSE 472 + LI+FVA+ LS HKRPREVR+VDALPRNALGKV K +L ++ Sbjct 425 NGPELIDFVARHLSAHKRPREVRLVDALPRNALGKVQKSRLAAD 468 >gi|145595459|ref|YP_001159756.1| acyl-CoA synthetase [Salinispora tropica CNB-440] gi|145304796|gb|ABP55378.1| AMP-dependent synthetase and ligase [Salinispora tropica CNB-440] Length=469 Score = 487 bits (1253), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 275/471 (59%), Positives = 331/471 (71%), Gaps = 9/471 (1%) Query 6 LNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITG 65 LN SA + DAV+I+G + +L A +VA+ + G RVAV A +TV+ + G Sbjct 4 LNWLSESADERPDAVQINGRGVPWVELRRLAAAVADDLHGLDRVAVEAGTDLATVVGVAG 63 Query 66 CLIAGVPVVPVPADVGVTERRHMLTDSGVQAWL----GPLPDDPAGLPHIPVRTHARSWH 121 L+AG VVPVP D G ER H+L DS +A L G D AG P IPV RS Sbjct 64 ALLAGTAVVPVPPDAGPRERDHLLRDSAAEAVLVPAHGKCRGDYAGRPRIPVDLTHRSDS 123 Query 122 RYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYH 181 PEP P A+++YTSGTTG PKG LSRRA+AA LD LA+AW WT +D+LVHGLPL+H Sbjct 124 TRPEPDPAGTALILYTSGTTGAPKGAVLSRRAVAACLDGLADAWGWTPDDLLVHGLPLFH 183 Query 182 VHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGA 241 VHGLVLG+LG LR G+R H G+PTP YA A G+L+FGVPT+WSR+ A AA A Sbjct 184 VHGLVLGVLGPLRLGSRLHHVGRPTPERYAGAA----GSLYFGVPTIWSRITAVPEAARA 239 Query 242 LKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPL 301 L+ ARLLVSGSAALP V L LTG R V+RYG +E+LIT+S ADG RP VGLPL Sbjct 240 LRSARLLVSGSAALPAAVGTDLAALTGRRVVQRYGMTETLITVSAHADGPHRPDTVGLPL 299 Query 302 AGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAV 361 GV+TRLVDD +P DGET+G+LQV GPTLFDGYL++P+A AA+ +D W+RTGDVA Sbjct 300 PGVRTRLVDDGDVPLPADGETMGELQVCGPTLFDGYLHRPEADAASRTSDGWFRTGDVAT 359 Query 362 VDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAY 421 + G HRIVGR + DLIKSGGYR+GAGE+E LL HP V EAAVVG+PD DLGQ++ AY Sbjct 360 IGPDGWHRIVGRAATDLIKSGGYRIGAGEVEDALLAHPGVREAAVVGIPDSDLGQQVTAY 419 Query 422 VVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSE 472 VV S +V LI+FVA+QLS HKRPR+VR VDALPRNALGKV K QL +E Sbjct 420 VV-SDDVAESELIDFVARQLSAHKRPRQVRRVDALPRNALGKVQKSQLTTE 469 >gi|317506368|ref|ZP_07964179.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974] gi|316255331|gb|EFV14590.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974] Length=464 Score = 485 bits (1249), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 274/454 (61%), Positives = 320/454 (71%), Gaps = 6/454 (1%) Query 20 VRIDGDVLSRSDLVGAATSVAERVA--GAHRVAVLATPTASTVLAITGCLIAGVPVVPVP 77 +R+ + L DL+ AAT+VAERV GA RVAV ATP +++A+ G L AGVPVV V Sbjct 12 LRVGDETLEGPDLLAAATAVAERVLILGARRVAVFATPELRSLVAVLGALRAGVPVVLVS 71 Query 78 ADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMVVYT 137 G E H+L DS AWLG PD + LP IP+ HARSWH PEP A A+V+YT Sbjct 72 PHSGSAELAHVLADSEPDAWLGFAPDQ-SDLPRIPISVHARSWHALPEPPADAPALVLYT 130 Query 138 SGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLRFGN 197 SGTTGPPKGV LSRRA+A LDALAEAW+WT +D + HGLP++H+HGLVLG LG LR G Sbjct 131 SGTTGPPKGVVLSRRALAGCLDALAEAWEWTGKDTVAHGLPVFHLHGLVLGTLGPLRLGG 190 Query 198 RFVHTGKPTPAGYAQA--CYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAAL 255 HT +PTP YA+A E T+ F VPTVWSR+ + A AL ARLLVSGSA L Sbjct 191 GSTHTVRPTPQAYAEAVASKEHAATMLFAVPTVWSRIVREPEHARALGRARLLVSGSAPL 250 Query 256 PVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGGE 315 P+PV L G PVERYG SE++ITLSTRA GERR G VGLPL GVQTRL + G Sbjct 251 PIPVAAALADSAGQVPVERYGMSETIITLSTRAGGERRLGSVGLPLRGVQTRLRSESGEP 310 Query 316 VPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGRES 375 V DGETVG+L+VR P LF YL +P+AT+A+F D W+ TGD+A V G HRIVGRES Sbjct 311 VAEDGETVGRLEVRAPWLFSEYLGKPEATSASFAGDGWFSTGDLATVGPDGFHRIVGRES 370 Query 376 VDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGLIN 435 VDLIKSGGYR+GAGE+E LL HP VAEAAVVGVPD+DLGQRIVA+VV V A L+ Sbjct 371 VDLIKSGGYRIGAGEVEAALLDHPAVAEAAVVGVPDEDLGQRIVAWVVAD-GVGAQELVA 429 Query 436 FVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 FVA LS HKRPRE+R V LPRN +GKVLK+ L Sbjct 430 FVASSLSTHKRPREIRFVSELPRNPMGKVLKRDL 463 >gi|296393265|ref|YP_003658149.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM 44985] gi|296180412|gb|ADG97318.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM 44985] Length=458 Score = 483 bits (1243), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 282/452 (63%), Positives = 319/452 (71%), Gaps = 8/452 (1%) Query 20 VRIDGDVLSRSDLVGAATSVAERV--AGAHRVAVLATPTASTVLAITGCLIAGVPVVPVP 77 +R+ + L DL AAT+VAERV AG RVAV ATP +++A+ G L AGVP V V Sbjct 12 LRVGSEALEGPDLAAAATAVAERVLTAGVRRVAVFATPELRSLVAVLGALRAGVPAVLVS 71 Query 78 ADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMVVYT 137 G E H+L DS AWLG PD A +IPV THARSWH PEP+P A+V+YT Sbjct 72 PHSGAAELAHVLADSKPDAWLGAAPDG-AACANIPVSTHARSWHTLPEPAPQQPALVLYT 130 Query 138 SGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLRFGN 197 SGTTGPPKGV +SR AIA LDALAEAW WT DV+ HGLPL+H+HGLVLG LG LRFG Sbjct 131 SGTTGPPKGVVVSRLAIAGCLDALAEAWGWTGADVVAHGLPLFHLHGLVLGSLGPLRFGG 190 Query 198 RFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAALPV 257 HT +P+P YAQA T++F VPTVWSR+ + A AL ARLLVSGSA LPV Sbjct 191 GSTHTVRPSPQAYAQA----KATMWFAVPTVWSRIVREPEHAKALGGARLLVSGSAPLPV 246 Query 258 PVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGGEVP 317 PV L L G PVERYG SE+LITLSTRADGERR G VG LAG QTRL + G EV Sbjct 247 PVGLALADLAGQSPVERYGMSETLITLSTRADGERRLGSVGTALAGAQTRLRSETGDEVA 306 Query 318 HDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGRESVD 377 DGETVG+LQVR P LF YL +PDAT A F D W+ TGD+A + G HRIVGRESVD Sbjct 307 ADGETVGRLQVRAPWLFSEYLGKPDATRACFTDDGWFSTGDLATIGEDGFHRIVGRESVD 366 Query 378 LIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGLINFV 437 LIKSGGYRVGAGE+E LL HP VAEAAVVGVPDDDLGQRIVA+VV D + LI+FV Sbjct 367 LIKSGGYRVGAGEVEAALLNHPAVAEAAVVGVPDDDLGQRIVAWVVADGVGDKE-LIDFV 425 Query 438 AQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 A LS HKRPREVR V LPRN +GKVLK++L Sbjct 426 AASLSTHKRPREVRFVPELPRNPMGKVLKREL 457 >gi|159038692|ref|YP_001537945.1| acyl-CoA synthetase [Salinispora arenicola CNS-205] gi|157917527|gb|ABV98954.1| AMP-dependent synthetase and ligase [Salinispora arenicola CNS-205] Length=469 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 273/465 (59%), Positives = 332/465 (72%), Gaps = 9/465 (1%) Query 12 SAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGV 71 SA + DAVRI+ +S +L AT+VA+ + G RVAV A+ +TV+ + G L AG Sbjct 10 SADERPDAVRINDQSVSWVELRRLATAVADDLRGLDRVAVEASTDLATVVGVVGALQAGT 69 Query 72 PVVPVPADVGVTERRHMLTDSGVQAWLGPL----PDDPAGLPHIPVRTHARSWHRYPEPS 127 VVPVP D G ER H+L DS +A L P D G P +PV RS PEP Sbjct 70 AVVPVPPDSGPMERDHILRDSSAEAVLVPAGSQRQGDYLGRPIVPVDLTHRSDSTLPEPD 129 Query 128 PGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVL 187 P A+++YTSGTTG PKGV LSRRA+AA LD LA AW WT +D+LVHGLPL+HVHGLVL Sbjct 130 PTGTALILYTSGTTGAPKGVVLSRRAVAACLDGLAAAWGWTQDDLLVHGLPLFHVHGLVL 189 Query 188 GLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARL 247 G+LG LR G+R H G+PTP YA+A +G+L+FGVPTVWSR+AA AA AL+ ARL Sbjct 190 GVLGPLRLGSRLHHVGRPTPERYARA----NGSLYFGVPTVWSRIAAAPDAARALRSARL 245 Query 248 LVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTR 307 LVSGSAALP V L LTG R VERYG +E+LIT+S RADG RPG VGLPL GV+TR Sbjct 246 LVSGSAALPATVCADLAALTGRRIVERYGMTETLITVSARADGPHRPGTVGLPLPGVRTR 305 Query 308 LVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGM 367 +VD+ +P DG+T+G+LQV GPTLFDGYL++P+A AA+ +D W+RTGDVA V G Sbjct 306 VVDERDAPLPADGDTMGELQVCGPTLFDGYLHRPEADAASHTSDGWFRTGDVATVGPDGW 365 Query 368 HRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSAN 427 HRIVGR + DLIKSGGYR+GAGE+E LL HP V EAAVVG P DLGQ++ AYVV S Sbjct 366 HRIVGRAATDLIKSGGYRIGAGEVEDALLTHPGVREAAVVGTPHPDLGQQVTAYVV-SDG 424 Query 428 VDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSE 472 V L++FVA+QLS HKRPR+VR+VDALPRNALGKV K +L ++ Sbjct 425 VPESELVDFVARQLSAHKRPRQVRLVDALPRNALGKVQKSRLAAD 469 >gi|337766095|emb|CCB74806.1| Acyl-CoA synthetase [Streptomyces cattleya NRRL 8057] Length=470 Score = 477 bits (1227), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 294/459 (65%), Positives = 340/459 (75%), Gaps = 8/459 (1%) Query 15 DIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVV 74 D DAV +DG S +L+GAA +VA RVAGA VAV ATPTA TV+A+ G L+AGVPVV Sbjct 13 DRRDAVVVDGRAFSYEELLGAAGAVAARVAGAPAVAVHATPTARTVVAVVGALLAGVPVV 72 Query 75 PVPADVGVTERRHMLTDSGVQAWL-GPLPDDPA--GLP-HIPVRTHARSWHRYPEPSPGA 130 PVP D G ER H+L DSG L G D PA G P H+PV R+ R + SP Sbjct 73 PVPPDAGPAERGHILRDSGAALLLTGAGADHPAAGGEPEHLPVDPDERAGFRAVDASPDH 132 Query 131 IAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLL 190 A+++YTSGTTG PKGV + RRA+AA LDALAEAW W AED LVHGLPL+HVHGLVLG+L Sbjct 133 PALILYTSGTTGAPKGVLIPRRAVAAGLDALAEAWAWNAEDTLVHGLPLFHVHGLVLGVL 192 Query 191 GSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVS 250 G+LR G+R VHTG+PTP YA+A GT++FGVPTVW+RV D AAA L ARLLVS Sbjct 193 GALRTGSRLVHTGRPTPERYARAG----GTVYFGVPTVWTRVVRDAAAARELGGARLLVS 248 Query 251 GSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVD 310 GSA LP PVF +L +LTG PVERYG +E+LIT+STRADGERRPG VGLP+AGV TRLV Sbjct 249 GSAPLPTPVFHELARLTGKPPVERYGMTETLITVSTRADGERRPGSVGLPVAGVATRLVG 308 Query 311 DDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRI 370 +DG VP+DG TVG+LQV GPTLF GYL +P+ATAAA AD W+RTGD+AV+ GMHRI Sbjct 309 EDGSPVPYDGATVGELQVSGPTLFSGYLGRPEATAAATTADGWFRTGDMAVIGADGMHRI 368 Query 371 VGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDA 430 VGR S DLIKSGGYR+GAGE+E LL HP V EAAVVG P DLGQ+IVAYVV V Sbjct 369 VGRASTDLIKSGGYRIGAGEVENALLDHPAVREAAVVGAPHPDLGQQIVAYVVTEGEVGE 428 Query 431 DGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 LI+FVA LSVHKRPR V + +LPRNA+GK KK L Sbjct 429 RELIDFVAGHLSVHKRPRIVVFLPSLPRNAMGKPQKKLL 467 >gi|345015718|ref|YP_004818072.1| AMP-dependent synthetase and ligase [Streptomyces violaceusniger Tu 4113] gi|344042067|gb|AEM87792.1| AMP-dependent synthetase and ligase [Streptomyces violaceusniger Tu 4113] Length=459 Score = 472 bits (1214), Expect = 7e-131, Method: Compositional matrix adjust. Identities = 278/456 (61%), Positives = 335/456 (74%), Gaps = 15/456 (3%) Query 15 DIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVV 74 D DA+ + G LSR +L+GAA +VA R+AGA VAV AT T TV+A+ G L+AGVPVV Sbjct 15 DRPDALSVGGRSLSREELLGAAGAVAARIAGAPVVAVRATATPETVVAVVGALLAGVPVV 74 Query 75 PVPADVGVTERRHMLTDSGVQAWL-GPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAM 133 PVP D G ER H+L DSG L G + P + +PV R+ PEP + A Sbjct 75 PVPPDSGPAERDHILRDSGATLLLTGEAIEAP--IETVPVDPAERAAWTKPEPDAESTAF 132 Query 134 VVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSL 193 ++YTSGTTG PKG +SRRA+AADLD LA AW WTAED LVHGLPL+HVHGLVLG+LG+L Sbjct 133 ILYTSGTTGAPKGALISRRAVAADLDGLAAAWAWTAEDTLVHGLPLFHVHGLVLGVLGAL 192 Query 194 RFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSA 253 R G+R VHTGKPTPA YA A G+L+FGVPTVW+R+ DQ +A AL ARLLVSGSA Sbjct 193 RTGSRLVHTGKPTPAAYAAAG----GSLYFGVPTVWNRIVQDQDSARALASARLLVSGSA 248 Query 254 ALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDG 313 LP PVF L +LTG RP+ERYG +ESLITLSTRADGERRPG+VG PLAG++TR+ ++G Sbjct 249 PLPAPVFRDLERLTGQRPIERYGMTESLITLSTRADGERRPGYVGTPLAGIRTRIATEEG 308 Query 314 GEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGR 373 E+ G+LQ+ GPTLFDGYLN+P+ATA ++ D W+RTGD+A V+ G HRIVGR Sbjct 309 AEI-------GELQLTGPTLFDGYLNRPEATAGSYTEDGWFRTGDIAAVEQDGFHRIVGR 361 Query 374 ESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGL 433 S D+IKSGGYR+GAGE+E LL HP V EAAVVG P +DLGQ IVAYVV + L Sbjct 362 ASTDMIKSGGYRIGAGEVENALLDHPAVREAAVVGAPHEDLGQEIVAYVVAD-GIGEQEL 420 Query 434 INFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 I+FVA QLSVHKRPR+VR ++ALPRNA+GK KK L Sbjct 421 IDFVASQLSVHKRPRKVRFLEALPRNAMGKPQKKLL 456 >gi|297561651|ref|YP_003680625.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296846099|gb|ADH68119.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=466 Score = 468 bits (1204), Expect = 1e-129, Method: Compositional matrix adjust. Identities = 286/459 (63%), Positives = 337/459 (74%), Gaps = 3/459 (0%) Query 12 SAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGV 71 S AD AV + G L R L AA +VAERVAGA VAV + STV+A+ G L+AGV Sbjct 5 SGADEGTAVSVGGAGLDREGLWSAAAAVAERVAGADAVAVHGEASLSTVVAVVGGLLAGV 64 Query 72 PVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAI 131 PVVPVPAD G ERRH++ DSG WLG P + LP +PV RS PEP P + Sbjct 65 PVVPVPADSGTAERRHIVRDSGAALWLG-APREDVDLPVVPVDPAERSSFALPEPPPEST 123 Query 132 AMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLG 191 A+V+YTSGTTGPPKG + RRA+AADLDALA+AW WT +DVLVHGLPL+HVHGL+LG+LG Sbjct 124 ALVMYTSGTTGPPKGALIPRRAVAADLDALADAWDWTPDDVLVHGLPLFHVHGLILGVLG 183 Query 192 SLRFGNRFVHTGKPTPAGYAQACYEAH-GTLFFGVPTVWSRVAADQAAAGALKPARLLVS 250 +LR G+ +HT +PTPA YA A GTLFFGVPTVWSR+A D +A AL ARLLVS Sbjct 184 ALRVGSPLLHTVRPTPAAYAAAAQGTRRGTLFFGVPTVWSRIARDPDSARALSGARLLVS 243 Query 251 GSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVD 310 GSA LP V D L GH PVERYG +E+LIT++ RAD RR GWVG L G++TRL Sbjct 244 GSAPLPDTVADGLRGACGHSPVERYGMTETLITVAARADAPRRTGWVGTALPGLETRLRG 303 Query 311 DDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRI 370 + G V DGE+VG+LQVRG TLF GYL P+ATAAA+ D W+RTGD AV DG G HRI Sbjct 304 EHGEPVASDGESVGELQVRGATLFGGYLGLPEATAAAWTGDGWFRTGDAAVRDGDGWHRI 363 Query 371 VGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDA 430 VGR SVD+IK+GGYRVGAGE+E VLLGHP V EAAVVG DDDLGQRIVAY+VG + Sbjct 364 VGRMSVDMIKTGGYRVGAGEVEAVLLGHPGVMEAAVVGEADDDLGQRIVAYLVGE-GISP 422 Query 431 DGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 + +I+FVA++LSVHKRPREVR+VD LPRNA+GK+ KK L Sbjct 423 EAVIDFVAERLSVHKRPREVRVVDTLPRNAMGKIQKKLL 461 >gi|86741668|ref|YP_482068.1| acyl-CoA synthetase [Frankia sp. CcI3] gi|86568530|gb|ABD12339.1| AMP-dependent synthetase and ligase [Frankia sp. CcI3] Length=498 Score = 467 bits (1202), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 281/485 (58%), Positives = 334/485 (69%), Gaps = 41/485 (8%) Query 19 AVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVPA 78 AVR+ +R++L AA+ VA RVAGA VAV A T +TV+++ GCL+AGVP VPVP Sbjct 15 AVRVGEVEFTRAELFAAASVVAGRVAGAPAVAVHAEATMATVVSVVGCLLAGVPAVPVPP 74 Query 79 DVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYP-------EPSPGAI 131 D G ER H+L DSG LG D +P +PV ARS E P Sbjct 75 DSGPRERGHILRDSGAALLLGRPAWDNLAIPTVPVDLTARSGSAGSGSGSGSGETGP--- 131 Query 132 AMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLG 191 A+++YTSGTTG PKGV LS AIAADLDALA+AW WT ED LVHGLPL+HVHGLVLG+LG Sbjct 132 ALILYTSGTTGAPKGVVLSAPAIAADLDALADAWAWTPEDTLVHGLPLFHVHGLVLGVLG 191 Query 192 SLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSG 251 +LR G+R +HT +PTP YA A GTL+FGVPTVWSRV D A AL ARLLVSG Sbjct 192 ALRVGSRLIHTVRPTPTAYAAAG----GTLYFGVPTVWSRVCDDPTTARALVSARLLVSG 247 Query 252 SAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDD 311 SA LP PV D+L LTG P+ERYG +E+LIT+S RADGERR GWVG L GV+ RLVDD Sbjct 248 SAPLPRPVIDRLTGLTGLAPIERYGMTETLITISARADGERRAGWVGTTLPGVRARLVDD 307 Query 312 DGG-EVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRI 370 + G E+P DGE++G+LQVRG TLFDGYL +P+ TAA+F AD W+RTGD AVV G HRI Sbjct 308 ETGTELPADGESIGELQVRGATLFDGYLGRPEVTAASFTADGWFRTGDAAVVAPDGHHRI 367 Query 371 VGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVG------ 424 VGR S DLIKSGGYRVGAGE+E VLL HP V EAAVVG+PDDDLGQRI A+VV Sbjct 368 VGRRSTDLIKSGGYRVGAGEVEAVLLAHPAVREAAVVGLPDDDLGQRIAAFVVAPDLAGA 427 Query 425 -------------------SANVDA-DGLINFVAQQLSVHKRPREVRIVDALPRNALGKV 464 +AN A + LI+FVA++LS+HKRPRE+ +V LPRN++GK+ Sbjct 428 AGGAPGGIPGRASDGTPSETANETASEALIDFVARELSIHKRPREIHLVAELPRNSMGKI 487 Query 465 LKKQL 469 K L Sbjct 488 RKSAL 492 >gi|297157954|gb|ADI07666.1| acyl-CoA synthetase [Streptomyces bingchenggensis BCW-1] Length=466 Score = 466 bits (1198), Expect = 5e-129, Method: Compositional matrix adjust. Identities = 279/461 (61%), Positives = 337/461 (74%), Gaps = 18/461 (3%) Query 15 DIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVV 74 D DA+ + G SR +L+GAA +VA R+AGA VAV A+PTA TV A+ G L+AGVPVV Sbjct 15 DRPDALTVGGRACSREELLGAAGAVAARIAGAPVVAVRASPTAETVTAVVGALLAGVPVV 74 Query 75 PVPADVGVTERRHMLTDSGVQAWL------GPLPDDPAGLPHIPVRTHARSWHRYPEPSP 128 PVP D G ER H+L DS L P ++ + +PV R+ PEP P Sbjct 75 PVPPDSGPAERDHILRDSKAALLLTGSLTGSPTEEEAGPVETVPVDLAERAAWSGPEPDP 134 Query 129 GAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLG 188 + A V+YTSGTTG PKG +SR A+AADLDALA AW WTAED LVHGLPL+HVHGLVLG Sbjct 135 ESTAFVLYTSGTTGAPKGALISRGAVAADLDALAGAWAWTAEDTLVHGLPLFHVHGLVLG 194 Query 189 LLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLL 248 +LG+LR G+R VHTG+PTPA YA A G+L+FGVPTVW RV D AA AL ARLL Sbjct 195 VLGALRVGSRLVHTGRPTPAAYAAAG----GSLYFGVPTVWHRVVQDPDAARALSGARLL 250 Query 249 VSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRL 308 VSGSA LP PVF L QLTGHRPVERYG +E+LIT+STRADGERRPG+VG PL+G++TR+ Sbjct 251 VSGSAPLPAPVFRDLEQLTGHRPVERYGMTETLITISTRADGERRPGYVGTPLSGIRTRV 310 Query 309 VDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMH 368 ++G E+ G+LQ+ GPTLFDGYLN+P+ATA ++ D W+RTGD+A V+ G H Sbjct 311 AAEEGAEI-------GELQLTGPTLFDGYLNRPEATAGSYTEDGWFRTGDIAAVEPDGFH 363 Query 369 RIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANV 428 RIVGR S DLIKSGGYR+GAGE+E LL HP V EAAVVG P +DLGQ+IVAYVV Sbjct 364 RIVGRASTDLIKSGGYRIGAGEVENALLDHPAVREAAVVGAPHEDLGQQIVAYVVADGVS 423 Query 429 DADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 +A+ LI++VA QLSVHKRPR+VR ++ALPRNA+GK KK L Sbjct 424 EAE-LIDYVAGQLSVHKRPRKVRFLEALPRNAMGKPQKKLL 463 >gi|302544822|ref|ZP_07297164.1| substrate-CoA ligase [Streptomyces hygroscopicus ATCC 53653] gi|302462440|gb|EFL25533.1| substrate-CoA ligase [Streptomyces himastatinicus ATCC 53653] Length=460 Score = 466 bits (1198), Expect = 5e-129, Method: Compositional matrix adjust. Identities = 285/468 (61%), Positives = 336/468 (72%), Gaps = 15/468 (3%) Query 2 LLASLNPAVVSAADIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVL 61 LL+SL D DA+ + G LSR DL+GAA +VA RVAGA VAV AT TA TV Sbjct 5 LLSSL---AAPGGDRPDALTVGGRALSREDLLGAAGAVAARVAGAPVVAVRATATAETVT 61 Query 62 AITGCLIAGVPVVPVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWH 121 A+ G L+AGVPVVPVP D G ER H+L DS L A + +PV R+ Sbjct 62 AVVGALLAGVPVVPVPPDSGPAERDHILRDSAATLLLTGDTGVEAPIETVPVDLTERAAW 121 Query 122 RYPEPSPGAIAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYH 181 PEP P + A+++YTSGTTG PKG +SRRA+AADLD LAEAW WT +D LVHGLPL+H Sbjct 122 TKPEPDPESTALILYTSGTTGAPKGALISRRAVAADLDGLAEAWAWTPDDTLVHGLPLFH 181 Query 182 VHGLVLGLLGSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGA 241 VHGLVLG+LG+LR G+R VHTGKPTPA YA A G+L+FGVPTVW+RV D +A A Sbjct 182 VHGLVLGVLGALRTGSRLVHTGKPTPAAYAAAG----GSLYFGVPTVWNRVVQDPESARA 237 Query 242 LKPARLLVSGSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPL 301 L ARLLVSGSA LP PVF L QLTG RPVERYG +ESLIT+STRA GERRPG VG P+ Sbjct 238 LSAARLLVSGSAPLPAPVFRDLEQLTGQRPVERYGMTESLITISTRAGGERRPGSVGTPI 297 Query 302 AGVQTRLVDDDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAV 361 GV+TR+V ++G E +G+LQ+ GPTLFDGYL + +ATA ++ D W+RTGD+A Sbjct 298 TGVRTRIVAEEGAE-------IGELQLTGPTLFDGYLGRSEATAGSYTEDGWFRTGDIAA 350 Query 362 VDGSGMHRIVGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAY 421 VD G HRIVGR S D+IKSGGYR+GAGE+E LL HP V EAAVVG P DDLGQ+IVAY Sbjct 351 VDPDGFHRIVGRASTDMIKSGGYRIGAGEVENALLDHPAVHEAAVVGAPHDDLGQQIVAY 410 Query 422 VVGSANVDADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 VV + D LI+FVA QLSVHKRPR+VR +DALPRNA+GK KK L Sbjct 411 VVADGVGEQD-LIDFVATQLSVHKRPRKVRFLDALPRNAMGKPQKKLL 457 >gi|311895109|dbj|BAJ27517.1| putative long-chain fatty-acid--CoA ligase [Kitasatospora setae KM-6054] Length=473 Score = 464 bits (1194), Expect = 1e-128, Method: Compositional matrix adjust. Identities = 291/465 (63%), Positives = 343/465 (74%), Gaps = 11/465 (2%) Query 15 DIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVV 74 D ADAV + G LS L+GAA +VAER AGA +AVLA PTA TV A+ G L+AGVPVV Sbjct 13 DRADAVTVAGTALSWEQLLGAAGAVAERAAGAPALAVLARPTAETVAAVVGGLLAGVPVV 72 Query 75 PVPADVGVTERRHMLTDSGVQAWLGP-LPDDPAGLPHIPVRTHAR---SWHRYPEPSPGA 130 P+P D G ER H+L DSG G LP+D GL +PV R W E P Sbjct 73 PLPPDSGPVERAHILRDSGATLLAGTALPEDAEGLTALPVDLADRPGGGWRPAAE-DPDR 131 Query 131 IAMVVYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLL 190 A V+YTSGTTG PKG + RA+AA LD LA+AWQW A D LVHGLPL+HVHGL+LG+L Sbjct 132 TAFVLYTSGTTGAPKGALIPHRAVAAGLDGLADAWQWDAGDTLVHGLPLFHVHGLLLGVL 191 Query 191 GSLRFGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVS 250 G+LR G+R VHTGKPTPAGYA A G+L+FGVPTVWSR+AA+ AA AL ARLLVS Sbjct 192 GALRTGSRLVHTGKPTPAGYAAA----RGSLYFGVPTVWSRIAAEPDAARALAGARLLVS 247 Query 251 GSAALPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVD 310 GSA LPVPVF++L LTG P ERYG +E+LIT++TRADGERRPG VG+PL G +TRLV Sbjct 248 GSAPLPVPVFERLRALTGQAPAERYGMTETLITVATRADGERRPGAVGVPLPGTRTRLVG 307 Query 311 DDGGEVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRI 370 +DG VP DGE+VG+LQV+GPTLFDGYL + +ATAA+ AD W+RTGDVAV+ G HRI Sbjct 308 EDGRPVPADGESVGELQVQGPTLFDGYLGRAEATAASRTADGWFRTGDVAVIGPDGFHRI 367 Query 371 VGRESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSAN--V 428 VGR SVDLIKSGGYR+GAGE+E L HP VA+AAVVG PD DLGQ +VAYVV + + Sbjct 368 VGRASVDLIKSGGYRIGAGEVEAALRDHPGVADAAVVGAPDPDLGQAVVAYVVANGEHVL 427 Query 429 DADGLINFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLLSEG 473 LI+FVA +LSVHKRPR + +V LPRNA+GKVLKKQLL +G Sbjct 428 GERELIDFVAGRLSVHKRPRRIVLVGDLPRNAMGKVLKKQLLEDG 472 >gi|331694181|ref|YP_004330420.1| Long-chain-fatty-acid--CoA ligase [Pseudonocardia dioxanivorans CB1190] gi|326948870|gb|AEA22567.1| Long-chain-fatty-acid--CoA ligase [Pseudonocardia dioxanivorans CB1190] Length=462 Score = 454 bits (1169), Expect = 1e-125, Method: Compositional matrix adjust. Identities = 283/451 (63%), Positives = 329/451 (73%), Gaps = 6/451 (1%) Query 19 AVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVVPVPA 78 AV + L RS+L AAT+VA R+AGA VAV + TV+++ G L+AGVPVVPVP+ Sbjct 15 AVTVGDRALRRSELWAAATAVAARIAGAPAVAVHGDASLETVVSVVGGLLAGVPVVPVPS 74 Query 79 DVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMVVYTS 138 D G ER H+L DSG WLGP P + L + V AR EP P A A+++YTS Sbjct 75 DAGTFERAHVLADSGAALWLGP-PTEGVSLERVAVDATARGGALPAEPDPDATALIMYTS 133 Query 139 GTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLRFGNR 198 GTTG PKGV +SRRAIAADLDALA+AW WTA+D LVHGLPL+HVHGLVLG LG+LR G+ Sbjct 134 GTTGKPKGVIMSRRAIAADLDALADAWAWTADDTLVHGLPLFHVHGLVLGTLGALRHGSP 193 Query 199 FVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAALPVP 258 VHT +P P YA A GTL+FGVPTVWSRVAAD AAA AL ARLLVSGSA LP Sbjct 194 LVHTVRPRPEAYAAAG----GTLYFGVPTVWSRVAADPAAARALSGARLLVSGSAGLPDR 249 Query 259 VFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGGEVPH 318 V + L L+G PVERYG +E+LIT++ RAD R GWVG P+AGV++RL + G VPH Sbjct 250 VAETLTALSGCSPVERYGMTETLITVAARADAPVRTGWVGTPVAGVESRLRTEHGDPVPH 309 Query 319 DGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVDGSGMHRIVGRESVDL 378 DG TVG LQVRG T+FDGYL P+ATAA++ D W+RTGD AVV G HRIVGR SVDL Sbjct 310 DGATVGDLQVRGATMFDGYLGLPEATAASWTDDGWFRTGDAAVVAEDGRHRIVGRISVDL 369 Query 379 IKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGLINFVA 438 IK+GGYRVGAGEIE LL HP V EAAVVG PDDDLGQRIVAYVVG +V D LI VA Sbjct 370 IKTGGYRVGAGEIEAALLDHPSVREAAVVGEPDDDLGQRIVAYVVGD-DVRPDELIAHVA 428 Query 439 QQLSVHKRPREVRIVDALPRNALGKVLKKQL 469 LS HKRPREVR++++LPRNA+GKV K QL Sbjct 429 GGLSTHKRPREVRVLESLPRNAMGKVQKTQL 459 >gi|302539402|ref|ZP_07291744.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. C] gi|302448297|gb|EFL20113.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. C] Length=461 Score = 451 bits (1161), Expect = 1e-124, Method: Compositional matrix adjust. Identities = 276/457 (61%), Positives = 322/457 (71%), Gaps = 27/457 (5%) Query 15 DIADAVRIDGDVLSRSDLVGAATSVAERVAGAHRVAVLATPTASTVLAITGCLIAGVPVV 74 D ADAVR+ G S +L+GAA +VA VAGA AV AT + TV A G L+AGVP V Sbjct 11 DRADAVRVAGRTASYEELLGAAGAVAADVAGAPAFAVTATASLETVAAAVGGLLAGVPFV 70 Query 75 PVPADVGVTERRHMLTDSGVQAWLGPLPDDPAGLPHIPVRTHARSWHRYPEPSPGAIAMV 134 P+P D G ER H+L DSG +PV R+ P A+V Sbjct 71 PLPPDAGPAEREHVLRDSGAV--------------EVPVDFARRAAAPARAAGPEDPALV 116 Query 135 VYTSGTTGPPKGVQLSRRAIAADLDALAEAWQWTAEDVLVHGLPLYHVHGLVLGLLGSLR 194 +YTSGTTGPPKGV L+ AIAADLDALA AWQWTAED LVHGLPL+HVHGLVLG+LG+LR Sbjct 117 LYTSGTTGPPKGVVLTAGAIAADLDALAGAWQWTAEDTLVHGLPLFHVHGLVLGVLGALR 176 Query 195 FGNRFVHTGKPTPAGYAQACYEAHGTLFFGVPTVWSRVAADQAAAGALKPARLLVSGSAA 254 G+R VHTG+PTP YA A G+L+FGVPTVWSR+AA+ A AL ARLLVSGSAA Sbjct 177 TGSRLVHTGRPTPQAYAAAG----GSLYFGVPTVWSRIAAEPEHAAALSGARLLVSGSAA 232 Query 255 LPVPVFDKLVQLTGHRPVERYGASESLITLSTRADGERRPGWVGLPLAGVQTRLVDDDGG 314 LP PVF L +LTGHRPVERYG +E+LIT+S RA G RPG VG PL G++TR+ + G Sbjct 233 LPAPVFRDLERLTGHRPVERYGMTETLITVSGRAGGGVRPGTVGTPLPGIRTRIAAEPGA 292 Query 315 EVPHDGETVGKLQVRGPTLFDGYLNQPDATAAAFDADSWYRTGDVAVVD-GSGMHRIVGR 373 E +G+LQ+ GPTLF GYL +PDATAAA+ D W+RTGD+A VD G+HRIVGR Sbjct 293 E-------IGELQLTGPTLFSGYLGRPDATAAAYTGDGWFRTGDIAAVDPEDGVHRIVGR 345 Query 374 ESVDLIKSGGYRVGAGEIETVLLGHPDVAEAAVVGVPDDDLGQRIVAYVVGSANVDADGL 433 S+D+IKSGGYR+GAGEIE LL HP VAEAAVVGVPD DLGQRIVA+VV A+ L Sbjct 346 ASIDMIKSGGYRIGAGEIENALLDHPKVAEAAVVGVPDADLGQRIVAFVVADGVTGAE-L 404 Query 434 INFVAQQLSVHKRPREVRIVDALPRNALGKVLKKQLL 470 +FVA LSVHKRPREVR V A+PRNA+GK KK LL Sbjct 405 TDFVAAHLSVHKRPREVRFVPAIPRNAMGKPQKKLLL 441 Lambda K H 0.318 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1003872181620 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40