BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv1207

Length=318
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|196049662|pdb|2VP8|A  Chain A, Structure Of Mycobacterium Tube...   626    1e-177
gi|15608347|ref|NP_215723.1|  dihydropteroate synthase 2 FolP2 [M...   625    2e-177
gi|298524705|ref|ZP_07012114.1|  dihydropteroate synthase 2 [Myco...   582    3e-164
gi|308231775|ref|ZP_07413713.2|  dihydropteroate synthase 2 folP2...   541    6e-152
gi|342862092|ref|ZP_08718735.1|  dihydropteroate synthase [Mycoba...   531    7e-149
gi|289749751|ref|ZP_06509129.1|  dihydropteroate synthase 2 folP2...   526    2e-147
gi|254774230|ref|ZP_05215746.1|  dihydropteroate synthase [Mycoba...   472    3e-131
gi|118463792|ref|YP_880596.1|  dihydropteroate synthase [Mycobact...   469    2e-130
gi|41408668|ref|NP_961504.1|  FolP2 [Mycobacterium avium subsp. p...   468    8e-130
gi|183984203|ref|YP_001852494.1|  dihydropteroate synthase 2 FolP...   465    4e-129
gi|118616719|ref|YP_905051.1|  dihydropteroate synthase 2 FolP2 [...   464    1e-128
gi|126436807|ref|YP_001072498.1|  dihydropteroate synthase [Mycob...   458    6e-127
gi|108800970|ref|YP_641167.1|  dihydropteroate synthase [Mycobact...   457    1e-126
gi|254822032|ref|ZP_05227033.1|  dihydropteroate synthase [Mycoba...   449    3e-124
gi|240169014|ref|ZP_04747673.1|  dihydropteroate synthase 2 FolP2...   444    6e-123
gi|15827518|ref|NP_301781.1|  dihydropteroate synthase [Mycobacte...   444    7e-123
gi|296170112|ref|ZP_06851711.1|  dihydropteroate synthase [Mycoba...   444    8e-123
gi|333989822|ref|YP_004522436.1|  dihydropteroate synthase 2 FolP...   432    2e-119
gi|118472372|ref|YP_889335.1|  dihydropteroate synthase [Mycobact...   432    3e-119
gi|120405461|ref|YP_955290.1|  dihydropteroate synthase [Mycobact...   431    1e-118
gi|145222774|ref|YP_001133452.1|  dihydropteroate synthase [Mycob...   430    1e-118
gi|253799749|ref|YP_003032750.1|  dihydropteroate synthase 2 folP...   412    4e-113
gi|169628438|ref|YP_001702087.1|  dihydropteroate synthase [Mycob...   397    1e-108
gi|343926927|ref|ZP_08766420.1|  putative dihydropteroate synthas...   394    1e-107
gi|111022931|ref|YP_705903.1|  dihydropteroate synthase [Rhodococ...   375    4e-102
gi|226365437|ref|YP_002783220.1|  dihydropteroate synthase [Rhodo...   371    7e-101
gi|312138867|ref|YP_004006203.1|  dihydropteroate synthase folp2 ...   370    1e-100
gi|229493849|ref|ZP_04387622.1|  dihydropteroate synthase [Rhodoc...   360    2e-97 
gi|226307654|ref|YP_002767614.1|  dihydropteroate synthase [Rhodo...   358    6e-97 
gi|331694882|ref|YP_004331121.1|  dihydropteroate synthase [Pseud...   353    3e-95 
gi|54026711|ref|YP_120953.1|  putative dihydropteroate synthase [...   351    8e-95 
gi|262203200|ref|YP_003274408.1|  dihydropteroate synthase [Gordo...   346    3e-93 
gi|72161718|ref|YP_289375.1|  dihydropteroate synthase [Thermobif...   340    2e-91 
gi|296138891|ref|YP_003646134.1|  dihydropteroate synthase [Tsuka...   339    3e-91 
gi|258652356|ref|YP_003201512.1|  dihydropteroate synthase [Nakam...   333    3e-89 
gi|134097619|ref|YP_001103280.1|  dihydropteroate synthase [Sacch...   332    6e-89 
gi|256397046|ref|YP_003118610.1|  dihydropteroate synthase [Caten...   328    7e-88 
gi|257055201|ref|YP_003133033.1|  Dihydropteroate synthase [Sacch...   325    5e-87 
gi|326381460|ref|ZP_08203154.1|  dihydropteroate synthase [Gordon...   322    4e-86 
gi|302536705|ref|ZP_07289047.1|  dihydropteroate synthase [Strept...   322    6e-86 
gi|297157497|gb|ADI07209.1|  dihydropteroate synthase [Streptomyc...   321    8e-86 
gi|295836669|ref|ZP_06823602.1|  dihydropteroate synthase [Strept...   321    8e-86 
gi|333024607|ref|ZP_08452671.1|  putative dihydropteroate synthas...   321    1e-85 
gi|297202183|ref|ZP_06919580.1|  dihydropteroate synthase [Strept...   320    3e-85 
gi|302521755|ref|ZP_07274097.1|  dihydropteroate synthase [Strept...   319    4e-85 
gi|337767981|emb|CCB76694.1|  Dihydropteroate synthase 2 [Strepto...   318    1e-84 
gi|333921013|ref|YP_004494594.1|  putative dihydropteroate syntha...   317    1e-84 
gi|318058423|ref|ZP_07977146.1|  dihydropteroate synthase [Strept...   317    2e-84 
gi|297560205|ref|YP_003679179.1|  dihydropteroate synthase [Nocar...   317    2e-84 
gi|29829665|ref|NP_824299.1|  dihydropteroate synthase [Streptomy...   316    3e-84 


>gi|196049662|pdb|2VP8|A Chain A, Structure Of Mycobacterium Tuberculosis Rv1207
 gi|196049663|pdb|2VP8|B Chain B, Structure Of Mycobacterium Tuberculosis Rv1207
Length=318

 Score =  626 bits (1615),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 318/318 (100%), Positives = 318/318 (100%), Gaps = 0/318 (0%)

Query  1    VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60
            VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA
Sbjct  1    VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60

Query  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120
            TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI
Sbjct  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120

Query  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180
            SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV
Sbjct  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180

Query  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV  240
            SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV
Sbjct  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV  240

Query  241  MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM  300
            MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM
Sbjct  241  MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM  300

Query  301  VASIQGVRPPTRTVRGLA  318
            VASIQGVRPPTRTVRGLA
Sbjct  301  VASIQGVRPPTRTVRGLA  318


>gi|15608347|ref|NP_215723.1| dihydropteroate synthase 2 FolP2 [Mycobacterium tuberculosis 
H37Rv]
 gi|15840651|ref|NP_335688.1| dihydropteroate synthase [Mycobacterium tuberculosis CDC1551]
 gi|31792400|ref|NP_854893.1| dihydropteroate synthase 2 FolP2 [Mycobacterium bovis AF2122/97]
 43 more sequence titles
 Length=318

 Score =  625 bits (1613),  Expect = 2e-177, Method: Compositional matrix adjust.
 Identities = 317/318 (99%), Positives = 318/318 (100%), Gaps = 0/318 (0%)

Query  1    VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60
            +RSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA
Sbjct  1    MRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60

Query  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120
            TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI
Sbjct  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120

Query  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180
            SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV
Sbjct  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180

Query  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV  240
            SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV
Sbjct  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV  240

Query  241  MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM  300
            MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM
Sbjct  241  MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM  300

Query  301  VASIQGVRPPTRTVRGLA  318
            VASIQGVRPPTRTVRGLA
Sbjct  301  VASIQGVRPPTRTVRGLA  318


>gi|298524705|ref|ZP_07012114.1| dihydropteroate synthase 2 [Mycobacterium tuberculosis 94_M4241A]
 gi|298494499|gb|EFI29793.1| dihydropteroate synthase 2 [Mycobacterium tuberculosis 94_M4241A]
Length=304

 Score =  582 bits (1500),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 295/295 (100%), Positives = 295/295 (100%), Gaps = 0/295 (0%)

Query  24   PALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVID  83
            PALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVID
Sbjct  10   PALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVID  69

Query  84   VGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLIND  143
            VGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLIND
Sbjct  70   VGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLIND  129

Query  144  TWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAER  203
            TWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAER
Sbjct  130  TWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAER  189

Query  204  AVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVD  263
            AVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVD
Sbjct  190  AVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVD  249

Query  264  LTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA
Sbjct  250  LTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  304


>gi|308231775|ref|ZP_07413713.2| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
SUMu001]
 gi|308370029|ref|ZP_07420051.2| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
SUMu002]
 gi|308370655|ref|ZP_07422248.2| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
SUMu003]
 24 more sequence titles
 Length=274

 Score =  541 bits (1394),  Expect = 6e-152, Method: Compositional matrix adjust.
 Identities = 274/274 (100%), Positives = 274/274 (100%), Gaps = 0/274 (0%)

Query  45   MAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL  104
            MAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL
Sbjct  1    MAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL  60

Query  105  VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV  164
            VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV
Sbjct  61   VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV  120

Query  165  CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK  224
            CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK
Sbjct  121  CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK  180

Query  225  NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR  284
            NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR
Sbjct  181  NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR  240

Query  285  MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA
Sbjct  241  MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  274


>gi|342862092|ref|ZP_08718735.1| dihydropteroate synthase [Mycobacterium colombiense CECT 3035]
 gi|342130396|gb|EGT83711.1| dihydropteroate synthase [Mycobacterium colombiense CECT 3035]
Length=318

 Score =  531 bits (1367),  Expect = 7e-149, Method: Compositional matrix adjust.
 Identities = 277/318 (88%), Positives = 292/318 (92%), Gaps = 0/318 (0%)

Query  1    VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60
            + STPPASAG+STPPA AG STPPA AG S LCGRPVAGDRALIMAI+NRTPDSFYDKGA
Sbjct  1    MHSTPPASAGQSTPPASAGQSTPPASAGRSMLCGRPVAGDRALIMAIINRTPDSFYDKGA  60

Query  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120
            TF D AAR AVH+AVADGADVIDVGGVKAGPG+ VD DTEI RLVPFIEWLR AYPDQLI
Sbjct  61   TFGDEAARAAVHQAVADGADVIDVGGVKAGPGQEVDADTEIARLVPFIEWLRDAYPDQLI  120

Query  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180
            S DTWR +VAK ACAAGADLINDTWGG+DPA+PEVAAEFGAGLVC+HTG ALPRTRPFRV
Sbjct  121  SADTWRCEVAKVACAAGADLINDTWGGIDPALPEVAAEFGAGLVCSHTGNALPRTRPFRV  180

Query  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLV  240
            +YGTTTRGVVD VI+QVT AAERAVA GVAR++VLIDP HDFGKNTFHGLLLLRHV DLV
Sbjct  181  NYGTTTRGVVDDVIAQVTTAAERAVACGVARDRVLIDPTHDFGKNTFHGLLLLRHVGDLV  240

Query  241  MTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEM  300
             TGWPVLMALSNKD VGETLGV+LTERLEGTLAATALAAAAGARMFRVH+VAATRRVLEM
Sbjct  241  NTGWPVLMALSNKDFVGETLGVELTERLEGTLAATALAAAAGARMFRVHQVAATRRVLEM  300

Query  301  VASIQGVRPPTRTVRGLA  318
            VASIQG RPP RTVRGLA
Sbjct  301  VASIQGTRPPARTVRGLA  318


>gi|289749751|ref|ZP_06509129.1| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
T92]
 gi|289690338|gb|EFD57767.1| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
T92]
Length=274

 Score =  526 bits (1354),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 269/274 (99%), Positives = 269/274 (99%), Gaps = 0/274 (0%)

Query  45   MAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL  104
            MAIVN  P   YDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL
Sbjct  1    MAIVNPHPGFVYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRL  60

Query  105  VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV  164
            VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV
Sbjct  61   VPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLV  120

Query  165  CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK  224
            CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK
Sbjct  121  CAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGK  180

Query  225  NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR  284
            NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR
Sbjct  181  NTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGAR  240

Query  285  MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA
Sbjct  241  MFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  274


>gi|254774230|ref|ZP_05215746.1| dihydropteroate synthase [Mycobacterium avium subsp. avium ATCC 
25291]
Length=291

 Score =  472 bits (1214),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 258/290 (89%), Positives = 270/290 (94%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST CGRPVAGDRALIMAI+NRTPDSFYD+GATFSD AAR AVHRAVA+GADVIDVGGVK
Sbjct  2    QSTFCGRPVAGDRALIMAIINRTPDSFYDRGATFSDDAARAAVHRAVAEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD DTEI RLVPFIEWLRGAYPDQLIS DTWRA+VAK ACAAGADLINDTWGGV
Sbjct  62   AGPGQDVDADTEIARLVPFIEWLRGAYPDQLISADTWRAEVAKVACAAGADLINDTWGGV  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+PEVAAEFGAGLVC+HTG ALPRTRPFRVSYGT+TRGVVD VI+QVTAAAERAV  G
Sbjct  122  DPALPEVAAEFGAGLVCSHTGNALPRTRPFRVSYGTSTRGVVDDVIAQVTAAAERAVGCG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VA ++VLIDP HDFGKNTFHGLLLLRHV DLV TGWPVLMALSNKD VGETLGV+LTERL
Sbjct  182  VAPDRVLIDPTHDFGKNTFHGLLLLRHVGDLVNTGWPVLMALSNKDFVGETLGVELTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVHEVA TRRVLEMVASIQG RPPTRTVRGLA
Sbjct  242  EGTLAATALAAAAGARMFRVHEVAPTRRVLEMVASIQGTRPPTRTVRGLA  291


>gi|118463792|ref|YP_880596.1| dihydropteroate synthase [Mycobacterium avium 104]
 gi|118165079|gb|ABK65976.1| dihydropteroate synthase [Mycobacterium avium 104]
 gi|336458626|gb|EGO37591.1| dihydropteroate synthase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=291

 Score =  469 bits (1207),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 257/290 (89%), Positives = 269/290 (93%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST CGRPVAGDRALIMAI+NRTPDSFYD+GATFSD AAR AVHRAVA+GADVIDVGGVK
Sbjct  2    QSTFCGRPVAGDRALIMAIINRTPDSFYDRGATFSDDAARAAVHRAVAEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD DTEI RLVPFIEWLR AYPDQLIS DTWRA+VAK ACAAGADLINDTWGGV
Sbjct  62   AGPGQDVDADTEIARLVPFIEWLRDAYPDQLISADTWRAEVAKVACAAGADLINDTWGGV  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+PEVAAEFGAGLVC+HTG ALPRTRPFRVSYGT+TRGVVD VI+QVTAAAERAV  G
Sbjct  122  DPALPEVAAEFGAGLVCSHTGNALPRTRPFRVSYGTSTRGVVDDVIAQVTAAAERAVGCG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VA ++VLIDP HDFGKNTFHGLLLLRHV DLV TGWPVLMALSNKD VGETLGV+LTERL
Sbjct  182  VAPDRVLIDPTHDFGKNTFHGLLLLRHVGDLVNTGWPVLMALSNKDFVGETLGVELTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVHEVA TRRVLEMVASIQG RPPTRTVRGLA
Sbjct  242  EGTLAATALAAAAGARMFRVHEVAPTRRVLEMVASIQGTRPPTRTVRGLA  291


>gi|41408668|ref|NP_961504.1| FolP2 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|41397026|gb|AAS04887.1| FolP2 [Mycobacterium avium subsp. paratuberculosis K-10]
Length=307

 Score =  468 bits (1203),  Expect = 8e-130, Method: Compositional matrix adjust.
 Identities = 257/290 (89%), Positives = 269/290 (93%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST CGRPVAGDRALIMAI+NRTPDSFYD+GATFSD AAR AVHRAVA+GADVIDVGGVK
Sbjct  18   QSTFCGRPVAGDRALIMAIINRTPDSFYDRGATFSDDAARAAVHRAVAEGADVIDVGGVK  77

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD DTEI RLVPFIEWLR AYPDQLIS DTWRA+VAK ACAAGADLINDTWGGV
Sbjct  78   AGPGQDVDADTEIARLVPFIEWLRDAYPDQLISADTWRAEVAKVACAAGADLINDTWGGV  137

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+PEVAAEFGAGLVC+HTG ALPRTRPFRVSYGT+TRGVVD VI+QVTAAAERAV  G
Sbjct  138  DPALPEVAAEFGAGLVCSHTGNALPRTRPFRVSYGTSTRGVVDDVIAQVTAAAERAVGCG  197

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VA ++VLIDP HDFGKNTFHGLLLLRHV DLV TGWPVLMALSNKD VGETLGV+LTERL
Sbjct  198  VAPDRVLIDPTHDFGKNTFHGLLLLRHVGDLVNTGWPVLMALSNKDFVGETLGVELTERL  257

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVHEVA TRRVLEMVASIQG RPPTRTVRGLA
Sbjct  258  EGTLAATALAAAAGARMFRVHEVAPTRRVLEMVASIQGTRPPTRTVRGLA  307


>gi|183984203|ref|YP_001852494.1| dihydropteroate synthase 2 FolP2 [Mycobacterium marinum M]
 gi|183177529|gb|ACC42639.1| dihydropteroate synthase 2 FolP2 [Mycobacterium marinum M]
Length=291

 Score =  465 bits (1197),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 262/290 (91%), Positives = 275/290 (95%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             +TLCGRPVAGDR LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVA+GADVIDVGGVK
Sbjct  2    QATLCGRPVAGDRPLIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVAEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPGE VD DTEI RLVPF+EWLR AYP+Q+ISVDTWR++VA+ ACAAGADLINDTW GV
Sbjct  62   AGPGEDVDPDTEIGRLVPFVEWLRDAYPEQVISVDTWRSEVARRACAAGADLINDTWAGV  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+ EVAAEFGAGLVCAHTGGA PRTRPFRVSYGTTTRGVVD VI +VTAAAERAVAAG
Sbjct  122  DPAIVEVAAEFGAGLVCAHTGGARPRTRPFRVSYGTTTRGVVDDVIREVTAAAERAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR++VLIDPAHDFGKNT+HGLLLLRHVADLV TGWPVLMALSNKD VGETLGVDLTERL
Sbjct  182  VARDRVLIDPAHDFGKNTWHGLLLLRHVADLVKTGWPVLMALSNKDFVGETLGVDLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQG RPPTRTVRGLA
Sbjct  242  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGTRPPTRTVRGLA  291


>gi|118616719|ref|YP_905051.1| dihydropteroate synthase 2 FolP2 [Mycobacterium ulcerans Agy99]
 gi|118568829|gb|ABL03580.1| dihydropteroate synthase 2 FolP2 [Mycobacterium ulcerans Agy99]
Length=291

 Score =  464 bits (1193),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 260/290 (90%), Positives = 275/290 (95%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             +TLCGRPVAGDR LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVA+GADVIDVGGVK
Sbjct  2    QATLCGRPVAGDRPLIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVAEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD DTEI RLVPF+EWLR AYP+Q+ISVDTWR++VA+ ACAAGADLINDTW GV
Sbjct  62   AGPGQDVDPDTEIGRLVPFVEWLRDAYPEQVISVDTWRSEVARRACAAGADLINDTWAGV  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+ EVAAEFGAGLVCAHTGGA PRTRPFRVSYGTTTRGVVD VI +VTAAAERAVAAG
Sbjct  122  DPAIVEVAAEFGAGLVCAHTGGARPRTRPFRVSYGTTTRGVVDDVIREVTAAAERAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR++VLIDPAHDFGKNT+HGLLLLRHVADLV TGWPVLMALSNKD VGETLGVDLTERL
Sbjct  182  VARDRVLIDPAHDFGKNTWHGLLLLRHVADLVKTGWPVLMALSNKDFVGETLGVDLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVHE+AATRRVLEMVASIQG RPPTRTVRGLA
Sbjct  242  EGTLAATALAAAAGARMFRVHEIAATRRVLEMVASIQGTRPPTRTVRGLA  291


>gi|126436807|ref|YP_001072498.1| dihydropteroate synthase [Mycobacterium sp. JLS]
 gi|126236607|gb|ABO00008.1| Dihydropteroate synthase [Mycobacterium sp. JLS]
Length=291

 Score =  458 bits (1178),  Expect = 6e-127, Method: Compositional matrix adjust.
 Identities = 236/290 (82%), Positives = 258/290 (89%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST CGRPVAGDRA+IMAIVNRTPDSFYD+GATF+D AA+ A +R V DGADV+DVGGVK
Sbjct  2    ESTFCGRPVAGDRAMIMAIVNRTPDSFYDRGATFTDEAAKSAAYRVVEDGADVVDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ V  D EI R+VPFIEWLRG +PD +ISVDTWRA VAK ACAAGADLINDTWGG 
Sbjct  62   AGPGQTVGADEEIARVVPFIEWLRGTFPDVVISVDTWRASVAKQACAAGADLINDTWGGS  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DP +PEVAAEF AGLVC+HTGGA+PRTRPFRV+YG T RGVVD VI++VT+AAERAVAAG
Sbjct  122  DPGLPEVAAEFNAGLVCSHTGGAVPRTRPFRVNYGITERGVVDDVIAEVTSAAERAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR+++LIDP HDFGKNT+HGL LLRHV +LV TGWPVLMALSNKD VGETLGV LTERL
Sbjct  182  VARDRILIDPTHDFGKNTYHGLSLLRHVEELVKTGWPVLMALSNKDFVGETLGVGLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAA AGA MFRVHEV  TRRVLEMVASIQGVRPPTRTVRGLA
Sbjct  242  EGTLAATALAAHAGAAMFRVHEVGPTRRVLEMVASIQGVRPPTRTVRGLA  291


>gi|108800970|ref|YP_641167.1| dihydropteroate synthase [Mycobacterium sp. MCS]
 gi|119870110|ref|YP_940062.1| dihydropteroate synthase [Mycobacterium sp. KMS]
 gi|108771389|gb|ABG10111.1| Dihydropteroate synthase [Mycobacterium sp. MCS]
 gi|119696199|gb|ABL93272.1| Dihydropteroate synthase [Mycobacterium sp. KMS]
Length=291

 Score =  457 bits (1175),  Expect = 1e-126, Method: Compositional matrix adjust.
 Identities = 235/290 (82%), Positives = 258/290 (89%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST CGRPVAGDRA+IMAIVNRTPDSFYD+GATF+D AA+ A +R V DGADV+DVGGVK
Sbjct  2    ESTFCGRPVAGDRAMIMAIVNRTPDSFYDRGATFTDEAAKSAAYRVVEDGADVVDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ V  D EI R+VPFIEWLRG +PD +ISVDTWRA VAK ACAAGADLINDTWGG 
Sbjct  62   AGPGQTVGADEEIARVVPFIEWLRGTFPDVVISVDTWRASVAKQACAAGADLINDTWGGS  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DP +PEVAAEF AGLVC+HTGGA+PRTRPFRV+YG T RGVVD VI++VT+AA+RAVAAG
Sbjct  122  DPGLPEVAAEFNAGLVCSHTGGAVPRTRPFRVNYGITERGVVDDVIAEVTSAAQRAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR+++LIDP HDFGKNT+HGL LLRHV +LV TGWPVLMALSNKD VGETLGV LTERL
Sbjct  182  VARDRILIDPTHDFGKNTYHGLSLLRHVEELVKTGWPVLMALSNKDFVGETLGVGLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAA AGA MFRVHEV  TRRVLEMVASIQGVRPPTRTVRGLA
Sbjct  242  EGTLAATALAAHAGAAMFRVHEVGPTRRVLEMVASIQGVRPPTRTVRGLA  291


>gi|254822032|ref|ZP_05227033.1| dihydropteroate synthase [Mycobacterium intracellulare ATCC 13950]
Length=282

 Score =  449 bits (1155),  Expect = 3e-124, Method: Compositional matrix adjust.
 Identities = 247/282 (88%), Positives = 261/282 (93%), Gaps = 0/282 (0%)

Query  37   VAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVD  96
            ++ DRALIMAIVNRTPDSFYD+GATFSD AAR AVHRAVADGADVIDVGGVKAGPG+ VD
Sbjct  1    MSADRALIMAIVNRTPDSFYDRGATFSDEAARAAVHRAVADGADVIDVGGVKAGPGQEVD  60

Query  97   VDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVA  156
             DTEI RLVPFIEWLR AYPD +IS DTWR++VAK ACAAGADLINDTW GVDPA+PEVA
Sbjct  61   ADTEIARLVPFIEWLRDAYPDHVISADTWRSEVAKVACAAGADLINDTWAGVDPALPEVA  120

Query  157  AEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLI  216
            AEFGAGLVC+HTG A PRTRPFRV+YGT TRGVVD VI+QVTAAAERAVA GVAR++VLI
Sbjct  121  AEFGAGLVCSHTGNAQPRTRPFRVNYGTATRGVVDDVIAQVTAAAERAVACGVARDRVLI  180

Query  217  DPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATA  276
            DP HDFGKNTFHGLLLLRHV DLV TGWPVLMALSNKD VGETLGV+LTERLEGTLAATA
Sbjct  181  DPTHDFGKNTFHGLLLLRHVGDLVDTGWPVLMALSNKDFVGETLGVELTERLEGTLAATA  240

Query  277  LAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LAAAAGARMFRVHEVAATRRVLEMVASIQG RPPTRTVRGLA
Sbjct  241  LAAAAGARMFRVHEVAATRRVLEMVASIQGTRPPTRTVRGLA  282


>gi|240169014|ref|ZP_04747673.1| dihydropteroate synthase 2 FolP2 [Mycobacterium kansasii ATCC 
12478]
Length=291

 Score =  444 bits (1143),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 244/290 (85%), Positives = 268/290 (93%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
            H+ LCGRPVA DR LIMAIVNRTPDSFYDKGATFS+ AAR+AVHRA+ +GADVIDVGGVK
Sbjct  2    HAMLCGRPVAADRPLIMAIVNRTPDSFYDKGATFSEGAAREAVHRAIDEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD  TEI RL+PF+EWLR AYP QLISVDTWR++VA+ ACAAGADLINDTWGGV
Sbjct  62   AGPGQDVDAGTEIARLLPFVEWLRDAYPHQLISVDTWRSEVARLACAAGADLINDTWGGV  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+P+VAAEFGAG+VCAHTGGA PRTRPFR+SYGT+ R VVD VI +VTAAAERAVAAG
Sbjct  122  DPAIPDVAAEFGAGVVCAHTGGAQPRTRPFRMSYGTSARAVVDDVIREVTAAAERAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR++VLIDPAHDFGKNTFHGL+LLRHV DLV TGWPVLMALSNKD +GETLGVD+T+RL
Sbjct  182  VARDRVLIDPAHDFGKNTFHGLMLLRHVDDLVKTGWPVLMALSNKDFIGETLGVDVTQRL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVH+VAATRRVLEMVASIQG RPP RTVRGLA
Sbjct  242  EGTLAATALAAAAGARMFRVHQVAATRRVLEMVASIQGTRPPARTVRGLA  291


>gi|15827518|ref|NP_301781.1| dihydropteroate synthase [Mycobacterium leprae TN]
 gi|221229995|ref|YP_002503411.1| dihydropteroate synthase [Mycobacterium leprae Br4923]
 gi|85682845|sp|P0C0X2.1|DHPS2_MYCLE RecName: Full=Inactive dihydropteroate synthase 2; Short=DHPS 
2; AltName: Full=Dihydropteroate pyrophosphorylase 2
 gi|699152|gb|AAA62918.1| folP [Mycobacterium leprae]
 gi|13093068|emb|CAC31444.1| dihydropteroate synthase [Mycobacterium leprae]
 gi|219933102|emb|CAR71158.1| dihydropteroate synthase [Mycobacterium leprae Br4923]
Length=291

 Score =  444 bits (1143),  Expect = 7e-123, Method: Compositional matrix adjust.
 Identities = 250/290 (87%), Positives = 261/290 (90%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             S LCGRPVA DR LIMAIVNRTPDSFYD+GATFSD AAR A HRAVA+GADVIDVGGVK
Sbjct  2    QSMLCGRPVAADRQLIMAIVNRTPDSFYDRGATFSDEAARAAAHRAVAEGADVIDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VDVDTEI RLVPFIEWLR AY D LISVDTWRA+VA+ AC AGADLIND+WGG 
Sbjct  62   AGPGQGVDVDTEIARLVPFIEWLRSAYTDLLISVDTWRAEVARLACTAGADLINDSWGGA  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPAM EVAAE GAGLVC+HTGGALPRTRPFRVSYGTTTRGVVD VI QVTAAAERAVAAG
Sbjct  122  DPAMHEVAAELGAGLVCSHTGGALPRTRPFRVSYGTTTRGVVDDVIRQVTAAAERAVAAG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            V R+ VL+DP HDFGKNTFHGLLLLRHV +LV TGWPVLM+LSNKD VGETLGV LTERL
Sbjct  182  VTRDSVLVDPTHDFGKNTFHGLLLLRHVDELVKTGWPVLMSLSNKDFVGETLGVGLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAG RMFRVHEV ATRRVLEMVASIQG RPPTRTVRGLA
Sbjct  242  EGTLAATALAAAAGVRMFRVHEVVATRRVLEMVASIQGTRPPTRTVRGLA  291


>gi|296170112|ref|ZP_06851711.1| dihydropteroate synthase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295895214|gb|EFG74927.1| dihydropteroate synthase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=329

 Score =  444 bits (1142),  Expect = 8e-123, Method: Compositional matrix adjust.
 Identities = 251/290 (87%), Positives = 268/290 (93%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
            HS+ CGRPVAGDR LIMAIVNRTPDSFYDKGATF D AAR A HRA+A+GADVIDVGGVK
Sbjct  40   HSSFCGRPVAGDRPLIMAIVNRTPDSFYDKGATFGDEAARAAAHRAIAEGADVIDVGGVK  99

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG+ VD  TEI RL+PFIEWLR AYPDQLISVDTWR++VA+ ACAAGADLINDTWGGV
Sbjct  100  AGPGQEVDAHTEIARLIPFIEWLREAYPDQLISVDTWRSEVARVACAAGADLINDTWGGV  159

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DPA+ EVAAEFGAGLVC+HTGGALPRTRPFRVSYG TTRGVVD VI QVTA AERAVA G
Sbjct  160  DPALAEVAAEFGAGLVCSHTGGALPRTRPFRVSYGITTRGVVDDVIRQVTAGAERAVARG  219

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            VAR++VLIDPAHDFGKNTFHGLLLLRH++DLV TGWPVLMALSNKD VGETLGV+LTERL
Sbjct  220  VARDRVLIDPAHDFGKNTFHGLLLLRHLSDLVNTGWPVLMALSNKDFVGETLGVELTERL  279

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAAAGARMFRVH+VA TRRVLEMVASIQG+RPP RTVRGLA
Sbjct  280  EGTLAATALAAAAGARMFRVHQVAETRRVLEMVASIQGIRPPARTVRGLA  329


>gi|333989822|ref|YP_004522436.1| dihydropteroate synthase 2 FolP2 [Mycobacterium sp. JDM601]
 gi|333485790|gb|AEF35182.1| dihydropteroate synthase 2 FolP2 [Mycobacterium sp. JDM601]
Length=282

 Score =  432 bits (1112),  Expect = 2e-119, Method: Compositional matrix adjust.
 Identities = 237/282 (85%), Positives = 251/282 (90%), Gaps = 0/282 (0%)

Query  37   VAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVD  96
            +A DRALIMAI+NRTPDSFYD GATF D AA+ AVH+AVADGADVID+GGVKAGPG+ VD
Sbjct  1    MAADRALIMAIINRTPDSFYDAGATFDDDAAKSAVHQAVADGADVIDIGGVKAGPGQTVD  60

Query  97   VDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVA  156
             D E  R+VPFIEWLRGAYPDQLISVDTWR++VAK AC AGADLINDTWGGVDP +P VA
Sbjct  61   ADAETARVVPFIEWLRGAYPDQLISVDTWRSEVAKRACVAGADLINDTWGGVDPQLPAVA  120

Query  157  AEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLI  216
            AEFG GLVC+HTGGA PRTRPFRVSYGTT  GVVDAVI +VTAAA+RAVAAGV REKVLI
Sbjct  121  AEFGVGLVCSHTGGAAPRTRPFRVSYGTTVDGVVDAVIDEVTAAAQRAVAAGVPREKVLI  180

Query  217  DPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATA  276
            DP HDFGKNTFHGL LLRH   LV TGWPVLMALSNKD +GETLGV LTERLEGTLAATA
Sbjct  181  DPTHDFGKNTFHGLALLRHTERLVATGWPVLMALSNKDFIGETLGVGLTERLEGTLAATA  240

Query  277  LAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LAAAAGARMFRVHEV  TRRVLEMVASIQGVR PTRTVRGLA
Sbjct  241  LAAAAGARMFRVHEVGPTRRVLEMVASIQGVRAPTRTVRGLA  282


>gi|118472372|ref|YP_889335.1| dihydropteroate synthase [Mycobacterium smegmatis str. MC2 155]
 gi|118173659|gb|ABK74555.1| dihydropteroate synthase [Mycobacterium smegmatis str. MC2 155]
Length=291

 Score =  432 bits (1112),  Expect = 3e-119, Method: Compositional matrix adjust.
 Identities = 232/289 (81%), Positives = 253/289 (88%), Gaps = 0/289 (0%)

Query  30   STLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKA  89
            ST CGRPVA DRALIMAIVNRTPDSFYD+GATF+D AA+ A HR + +GADVIDVGGVKA
Sbjct  3    STFCGRPVAHDRALIMAIVNRTPDSFYDRGATFTDEAAKAAAHRVIDEGADVIDVGGVKA  62

Query  90   GPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVD  149
            GPG  VD + EITR+VPFIEWLR  +PD+LIS+DTWRA VAK ACAAGAD+INDTW G D
Sbjct  63   GPGSNVDAEEEITRVVPFIEWLRSTFPDRLISIDTWRAAVAKQACAAGADIINDTWAGAD  122

Query  150  PAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGV  209
            P + EVAAEFGAGLVC+HTGGA PRTRPFRV+YG + RGVVD VI++VTAAAERAVA GV
Sbjct  123  PGLAEVAAEFGAGLVCSHTGGATPRTRPFRVNYGISERGVVDDVIAEVTAAAERAVATGV  182

Query  210  AREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLE  269
             R+++LIDP HDFGKNT+HGL LLRHV DLV TGWPVLMALSNKD VGETLGVDLTERLE
Sbjct  183  QRDRILIDPTHDFGKNTYHGLSLLRHVKDLVNTGWPVLMALSNKDFVGETLGVDLTERLE  242

Query  270  GTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            GTLAATALAAA GA MFRVHEV  TRRVLEMVASIQGVR P RTVRGLA
Sbjct  243  GTLAATALAAADGAAMFRVHEVGPTRRVLEMVASIQGVRKPARTVRGLA  291


>gi|120405461|ref|YP_955290.1| dihydropteroate synthase [Mycobacterium vanbaalenii PYR-1]
 gi|119958279|gb|ABM15284.1| Dihydropteroate synthase [Mycobacterium vanbaalenii PYR-1]
Length=282

 Score =  431 bits (1107),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 226/282 (81%), Positives = 248/282 (88%), Gaps = 0/282 (0%)

Query  37   VAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVD  96
            +AGDRALIMAIVNRTPDSFYD+GATF+D AA++A HR V DGAD+IDVGGVKAGPG  VD
Sbjct  1    MAGDRALIMAIVNRTPDSFYDRGATFTDDAAKEAAHRVVEDGADIIDVGGVKAGPGAIVD  60

Query  97   VDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVA  156
            VD EI R+VPFIEWLR  +PD++ISVDTWRA+VAK ACAAGADLINDTWGG DP +  VA
Sbjct  61   VDEEIARVVPFIEWLRATFPDRVISVDTWRAEVAKQACAAGADLINDTWGGADPDLAGVA  120

Query  157  AEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLI  216
            AEFGAGLVC+HTGGA+PRTRPFRV+YG + RGVVD VI++VT+AAERAVA GV R+ +LI
Sbjct  121  AEFGAGLVCSHTGGAVPRTRPFRVNYGLSERGVVDDVIAEVTSAAERAVALGVRRDGILI  180

Query  217  DPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATA  276
            DP HDFGKNT+HGL LLRHV DLV TGWPVLMALSNKD VGETLGV LTERLEGTLAATA
Sbjct  181  DPTHDFGKNTYHGLSLLRHVKDLVNTGWPVLMALSNKDFVGETLGVGLTERLEGTLAATA  240

Query  277  LAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LAAA GA MFRVHEV  TRRVLEMVASIQG RPP  TVRGLA
Sbjct  241  LAAADGAAMFRVHEVGPTRRVLEMVASIQGARPPKHTVRGLA  282


>gi|145222774|ref|YP_001133452.1| dihydropteroate synthase [Mycobacterium gilvum PYR-GCK]
 gi|315443241|ref|YP_004076120.1| dihydropteroate synthase [Mycobacterium sp. Spyr1]
 gi|145215260|gb|ABP44664.1| Dihydropteroate synthase [Mycobacterium gilvum PYR-GCK]
 gi|315261544|gb|ADT98285.1| Dihydropteroate synthase [Mycobacterium sp. Spyr1]
Length=291

 Score =  430 bits (1106),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 231/290 (80%), Positives = 256/290 (89%), Gaps = 0/290 (0%)

Query  29   HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVK  88
             ST  GRPVAGDRALIMAIVNRTPDSFYD+GATFSD AA++A HR +ADGAD++DVGGVK
Sbjct  2    QSTFLGRPVAGDRALIMAIVNRTPDSFYDRGATFSDDAAKEAAHRVIADGADIVDVGGVK  61

Query  89   AGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGV  148
            AGPG  VDVD EI R+VPFIEWLRG +PDQ+ISVDTWRA VAK ACAAGADLINDTWGG 
Sbjct  62   AGPGTTVDVDEEIARVVPFIEWLRGTFPDQVISVDTWRAAVAKQACAAGADLINDTWGGT  121

Query  149  DPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAG  208
            DP +  VAAEF AGLVC+HTGGA+PRTRPFRV+YG + RGVVD V+++VTAAAERAV+ G
Sbjct  122  DPDLAGVAAEFDAGLVCSHTGGAVPRTRPFRVNYGLSERGVVDDVLAEVTAAAERAVSLG  181

Query  209  VAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERL  268
            V+R+++LIDP HDFGKNT+HGL LLRHV +LV TGWPVLMALSNKD VGETLGV LTERL
Sbjct  182  VSRDRILIDPTHDFGKNTYHGLSLLRHVKELVNTGWPVLMALSNKDFVGETLGVGLTERL  241

Query  269  EGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            EGTLAATALAAA GA +FRVHEV  TRRVLEMVASIQG RPP RTVRGLA
Sbjct  242  EGTLAATALAAADGAAVFRVHEVGPTRRVLEMVASIQGARPPKRTVRGLA  291


>gi|253799749|ref|YP_003032750.1| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
KZN 1435]
 gi|253321252|gb|ACT25855.1| dihydropteroate synthase 2 folP2 [Mycobacterium tuberculosis 
KZN 1435]
Length=268

 Score =  412 bits (1058),  Expect = 4e-113, Method: Compositional matrix adjust.
 Identities = 212/215 (99%), Positives = 213/215 (99%), Gaps = 1/215 (0%)

Query  1    VRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60
            +RSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA
Sbjct  1    MRSTPPASAGRSTPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGA  60

Query  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120
            TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI
Sbjct  61   TFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLI  120

Query  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180
            SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV
Sbjct  121  SVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRV  180

Query  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVA-REKV  214
            SYGTTTRGVVDAVISQVTAAAERAVAAGVA RE V
Sbjct  181  SYGTTTRGVVDAVISQVTAAAERAVAAGVAPREGV  215


>gi|169628438|ref|YP_001702087.1| dihydropteroate synthase [Mycobacterium abscessus ATCC 19977]
 gi|169240405|emb|CAM61433.1| Probable dihydropteroate synthase 2 FolP2 [Mycobacterium abscessus]
Length=302

 Score =  397 bits (1020),  Expect = 1e-108, Method: Compositional matrix adjust.
 Identities = 226/289 (79%), Positives = 250/289 (87%), Gaps = 0/289 (0%)

Query  30   STLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKA  89
             T CGRPV  DRALIMAIVNRTPDSFYD+GATF+D AA+ AVH+AVADGADV+D+GGVKA
Sbjct  14   ETFCGRPVRTDRALIMAIVNRTPDSFYDRGATFTDEAAQAAVHQAVADGADVVDIGGVKA  73

Query  90   GPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVD  149
            GPGE VD D EI R+VPFIEW+RGA+PD LISVDTWRA+VA  ACAAGADLINDTW G D
Sbjct  74   GPGENVDADAEIARVVPFIEWVRGAHPDLLISVDTWRAEVAAKACAAGADLINDTWAGAD  133

Query  150  PAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGV  209
            P +P VAA +GAGLVC+HTGGA+PRTRP+RV YGT   GVV AV+ +VTA+AERA+A GV
Sbjct  134  PELPAVAAAYGAGLVCSHTGGAVPRTRPYRVHYGTEVDGVVRAVLDEVTASAERALALGV  193

Query  210  AREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLE  269
            +++ +LIDP HDFGKNTFHGL LLRHV DLV TGWPVLMALSNKD +GETLGV LTERLE
Sbjct  194  SKDAILIDPTHDFGKNTFHGLALLRHVNDLVNTGWPVLMALSNKDFIGETLGVGLTERLE  253

Query  270  GTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            GTLAATALAAAAGARMFRVHEV  TRR LEMV SI G RPP RTVRGLA
Sbjct  254  GTLAATALAAAAGARMFRVHEVGPTRRTLEMVGSIVGTRPPARTVRGLA  302


>gi|343926927|ref|ZP_08766420.1| putative dihydropteroate synthase [Gordonia alkanivorans NBRC 
16433]
 gi|343763287|dbj|GAA13346.1| putative dihydropteroate synthase [Gordonia alkanivorans NBRC 
16433]
Length=293

 Score =  394 bits (1012),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 211/288 (74%), Positives = 239/288 (83%), Gaps = 0/288 (0%)

Query  31   TLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAG  90
            TLCGRPVA DRAL+MAIVNRTPDSFYD+GA+F D AA+  V + VA+GAD+IDVGGVKAG
Sbjct  6    TLCGRPVAVDRALVMAIVNRTPDSFYDRGASFDDTAAQRRVDQVVAEGADIIDVGGVKAG  65

Query  91   PGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDP  150
            PGE VD  TE  R+VP I W+R  +PD LISVDTWR++VA  ACAAGADLINDTW GVDP
Sbjct  66   PGEEVDAMTEAARVVPMISWIRERHPDVLISVDTWRSEVADQACAAGADLINDTWAGVDP  125

Query  151  AMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVA  210
             +  VAAE GAG+VC+HTGGA+ RTRP RVSYG +   VV  V+ +VT AAERA+AAGV 
Sbjct  126  EVVAVAAERGAGIVCSHTGGAVVRTRPHRVSYGDSVDAVVADVLDEVTGAAERALAAGVH  185

Query  211  REKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEG  270
            R+ ++IDP HDFGKNT HGL LLR V DLV TGWPVLMALSNKD VGETLG DL +RLEG
Sbjct  186  RDAIVIDPTHDFGKNTHHGLALLRRVKDLVNTGWPVLMALSNKDFVGETLGTDLEQRLEG  245

Query  271  TLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            TLAATALAAA GAR+FRVHEVAATRRV++MVA+I G RPP RTVRGLA
Sbjct  246  TLAATALAAAEGARIFRVHEVAATRRVVDMVAAIAGTRPPARTVRGLA  293


>gi|111022931|ref|YP_705903.1| dihydropteroate synthase [Rhodococcus jostii RHA1]
 gi|110822461|gb|ABG97745.1| dihydropteroate synthase [Rhodococcus jostii RHA1]
Length=299

 Score =  375 bits (964),  Expect = 4e-102, Method: Compositional matrix adjust.
 Identities = 208/303 (69%), Positives = 240/303 (80%), Gaps = 5/303 (1%)

Query  17   LAGHSTPPALAGHS-TLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAV  75
            +A    PPA    S TLCGRPVA DRAL+MAIVNRTPDSFYD+GATF+D+AA  AV RAV
Sbjct  1    MAETDVPPAPDHLSPTLCGRPVAVDRALVMAIVNRTPDSFYDRGATFTDSAALSAVDRAV  60

Query  76   ADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACA  135
             +GAD++D+GGVKAGPG+ VD   E  R+VPF+  +R  YP+ LISVDTWR+ VA+ A A
Sbjct  61   DEGADLVDIGGVKAGPGDVVDAAEETRRVVPFVAAIRERYPELLISVDTWRSDVARLAVA  120

Query  136  AGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVIS  195
             G DLINDTW G DPA+ EVAAE GAG+VC+HTGGA+PRTRPFRV Y      VV  V+ 
Sbjct  121  EGTDLINDTWAGADPALVEVAAETGAGIVCSHTGGAVPRTRPFRVRYA----DVVADVLR  176

Query  196  QVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDV  255
            +V +AAE A   GV  + +LIDP HDFGKNT+HGL LLR V DLV TGWPVLMALSNKD 
Sbjct  177  EVVSAAENAARLGVPADSILIDPTHDFGKNTYHGLELLRRVEDLVNTGWPVLMALSNKDF  236

Query  256  VGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVR  315
            VGETLGVDL ERLEGTLAATA+AAA GAR+FRVHEVA TRRV++MVA+IQG R P+RTVR
Sbjct  237  VGETLGVDLVERLEGTLAATAMAAAGGARVFRVHEVAPTRRVVDMVAAIQGRRAPSRTVR  296

Query  316  GLA  318
            GLA
Sbjct  297  GLA  299


>gi|226365437|ref|YP_002783220.1| dihydropteroate synthase [Rhodococcus opacus B4]
 gi|226243927|dbj|BAH54275.1| putative dihydropteroate synthase [Rhodococcus opacus B4]
Length=299

 Score =  371 bits (953),  Expect = 7e-101, Method: Compositional matrix adjust.
 Identities = 212/303 (70%), Positives = 243/303 (81%), Gaps = 5/303 (1%)

Query  17   LAGHSTPPALAG-HSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAV  75
            +A    PPA     STLCGRPVA DRAL+MAIVNRTPDSFYD+GATF+D+AA  AV RAV
Sbjct  1    MADRDVPPAPDRPSSTLCGRPVAVDRALVMAIVNRTPDSFYDRGATFTDSAAMAAVERAV  60

Query  76   ADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACA  135
             +GAD++D+GGVKAGPG+ VD   EI R+VPF+  +RG YP+ L+SVDTWRA VA+ A A
Sbjct  61   DEGADLVDIGGVKAGPGDVVDSAEEIRRVVPFVAAIRGRYPELLVSVDTWRADVARLAVA  120

Query  136  AGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVIS  195
             GADLINDTW G DPA+ EVAAE GAG+VC+HTGGA+PRTRPFRV Y      VV  V+ 
Sbjct  121  EGADLINDTWAGADPALVEVAAETGAGIVCSHTGGAVPRTRPFRVRYSD----VVADVLE  176

Query  196  QVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDV  255
            +V AAAE A   GV  + +LIDP HDFGKNT+HGL LLR V DLV TGWPVLMALSNKD 
Sbjct  177  EVVAAAENAARLGVPADSILIDPTHDFGKNTYHGLELLRRVEDLVNTGWPVLMALSNKDF  236

Query  256  VGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVR  315
            VGETLGVDL ERLEGTLAATA+AAA GAR+FRVHEVA TRRV++MVA+IQG R P+RTVR
Sbjct  237  VGETLGVDLVERLEGTLAATAMAAAGGARVFRVHEVAPTRRVVDMVAAIQGRRAPSRTVR  296

Query  316  GLA  318
            GLA
Sbjct  297  GLA  299


>gi|312138867|ref|YP_004006203.1| dihydropteroate synthase folp2 [Rhodococcus equi 103S]
 gi|325676429|ref|ZP_08156107.1| dihydropteroate synthase [Rhodococcus equi ATCC 33707]
 gi|311888206|emb|CBH47518.1| dihydropteroate synthase FolP2 [Rhodococcus equi 103S]
 gi|325552607|gb|EGD22291.1| dihydropteroate synthase [Rhodococcus equi ATCC 33707]
Length=308

 Score =  370 bits (951),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 210/315 (67%), Positives = 240/315 (77%), Gaps = 13/315 (4%)

Query  6    PASAGRS--TPPALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFS  63
            PAS   S  + P   GH  P       TLCGRPVA DRAL+MAIVNRTPDSFYD+GATFS
Sbjct  5    PASDNDSVTSAPWAPGHVLP-------TLCGRPVATDRALVMAIVNRTPDSFYDRGATFS  57

Query  64   DAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVD  123
            D AA  AV RAV +GAD++D+GGVKAGPG  VD   E  R+VPF+E +R  YPD +ISVD
Sbjct  58   DEAAMAAVDRAVDEGADLVDIGGVKAGPGTLVDAAEETRRVVPFVEAIRARYPDVIISVD  117

Query  124  TWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYG  183
            TWR++VA+ ACA GADLINDTW G DP + EVAAE GAG+VC+HTGGA+PRTRP RV Y 
Sbjct  118  TWRSEVARLACAEGADLINDTWAGADPGLVEVAAELGAGIVCSHTGGAVPRTRPHRVRYA  177

Query  184  TTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTG  243
                     V+ +V  AAE A A GV  + +L+DP HDFGKNTFHGL LLR V DLV TG
Sbjct  178  DVVA----DVVDEVVRAAEHATALGVKSDSILVDPTHDFGKNTFHGLELLRRVEDLVNTG  233

Query  244  WPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVAS  303
            WPVLMALSNKD VGETLGV+L +RLEGTLAATALAAA GAR+FRVHEVA+TRRV++MVA+
Sbjct  234  WPVLMALSNKDFVGETLGVELADRLEGTLAATALAAAGGARVFRVHEVASTRRVVDMVAA  293

Query  304  IQGVRPPTRTVRGLA  318
            I G R P RTVRGLA
Sbjct  294  IMGTRQPVRTVRGLA  308


>gi|229493849|ref|ZP_04387622.1| dihydropteroate synthase [Rhodococcus erythropolis SK121]
 gi|229319236|gb|EEN85084.1| dihydropteroate synthase [Rhodococcus erythropolis SK121]
Length=299

 Score =  360 bits (923),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 205/303 (68%), Positives = 240/303 (80%), Gaps = 6/303 (1%)

Query  16   ALAGHSTPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAV  75
            +L G +  P  A   TLCGRPVA DRAL+MAIVNRTPDSFYD+GATFSD+AA  AV RAV
Sbjct  3    SLPGSTAQPGPA--PTLCGRPVAVDRALVMAIVNRTPDSFYDQGATFSDSAAMAAVDRAV  60

Query  76   ADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACA  135
             +GAD++D+GGVKAGPG+ VD D E+ R+VPF+  +R  YP+ +ISVDTWR+ VA+ A  
Sbjct  61   GEGADLVDIGGVKAGPGDLVDADEEVRRVVPFVAAIRAKYPELIISVDTWRSGVARLARG  120

Query  136  AGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVIS  195
             GADLINDTW G DP +  V AE GAG+VC+HTGGA+PRTRP RV Y      VV  V+S
Sbjct  121  EGADLINDTWAGADPELVVVTAETGAGIVCSHTGGAVPRTRPHRVRYDDVVADVVTEVVS  180

Query  196  QVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDV  255
                AAERA+A GV R+ +LIDP HDFGKNTFHGL LLR V  LV TGWPVLMALSNKD 
Sbjct  181  ----AAERALALGVPRDAILIDPTHDFGKNTFHGLELLRKVDVLVNTGWPVLMALSNKDF  236

Query  256  VGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVR  315
            +GETLGV+L+ERLEGTLAATA+AAA GAR+FRVHEVA+TRRV++MVA+IQG R P RTVR
Sbjct  237  IGETLGVELSERLEGTLAATAMAAAGGARVFRVHEVASTRRVVDMVAAIQGRRAPVRTVR  296

Query  316  GLA  318
            GLA
Sbjct  297  GLA  299


>gi|226307654|ref|YP_002767614.1| dihydropteroate synthase [Rhodococcus erythropolis PR4]
 gi|226186771|dbj|BAH34875.1| putative dihydropteroate synthase [Rhodococcus erythropolis PR4]
Length=302

 Score =  358 bits (919),  Expect = 6e-97, Method: Compositional matrix adjust.
 Identities = 201/288 (70%), Positives = 235/288 (82%), Gaps = 4/288 (1%)

Query  31   TLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAG  90
            TLCGRPVA DRAL+MAIVNRTPDSFYD+GATFSD++A  AV RAV +GAD++D+GGVKAG
Sbjct  19   TLCGRPVAVDRALVMAIVNRTPDSFYDQGATFSDSSAMAAVDRAVDEGADLVDIGGVKAG  78

Query  91   PGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDP  150
            PG+ VD D E+ R+VPF+  +R  YP+ +ISVDTWR+ VA+ A   GADLINDTW G DP
Sbjct  79   PGDLVDADEEVRRVVPFVAAIRAKYPELIISVDTWRSGVARLARGEGADLINDTWAGADP  138

Query  151  AMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVA  210
             +  VAAE GAG+VC+HTGGA+PRTRP RV Y      VV  V+S    AAERA+A GV 
Sbjct  139  DLVLVAAETGAGIVCSHTGGAVPRTRPHRVRYDDVVADVVTEVVS----AAERALALGVP  194

Query  211  REKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEG  270
            R+ +LIDP HDFGKNTFHGL LLR V  LV TGWPVLMALSNKD +GETLGV+L+ERLEG
Sbjct  195  RDAILIDPTHDFGKNTFHGLELLRKVDVLVNTGWPVLMALSNKDFIGETLGVELSERLEG  254

Query  271  TLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            TLAATA+AAA GAR+FRVHEVA+TRRV++MVA+IQG R P RTVRGLA
Sbjct  255  TLAATAMAAAGGARVFRVHEVASTRRVVDMVAAIQGRRAPVRTVRGLA  302


>gi|331694882|ref|YP_004331121.1| dihydropteroate synthase [Pseudonocardia dioxanivorans CB1190]
 gi|326949571|gb|AEA23268.1| dihydropteroate synthase [Pseudonocardia dioxanivorans CB1190]
Length=297

 Score =  353 bits (905),  Expect = 3e-95, Method: Compositional matrix adjust.
 Identities = 199/285 (70%), Positives = 226/285 (80%), Gaps = 5/285 (1%)

Query  35   RPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGER  94
            R +AGDRAL+MAIVNRTPDSFYD+GATFSD AA  AV RAV +GADVID+GGVKAGPG  
Sbjct  17   RTLAGDRALVMAIVNRTPDSFYDRGATFSDHAAMAAVERAVGEGADVIDIGGVKAGPGPV  76

Query  95   VDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPE  154
            VDV  E  R+VPF+  +R  +PD +ISVDTWR +V + A A GADL+NDTW G DP + E
Sbjct  77   VDVAEETRRVVPFVAAVRARHPDVVISVDTWRGEVGRLAVAEGADLLNDTWSGADPTLAE  136

Query  155  VAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKV  214
            VAA  GAG+VC+HTG A+PR RP RV Y      VV  VI++VT  AER VA GV RE +
Sbjct  137  VAAGTGAGIVCSHTGKAVPRLRPHRVRYAD----VVADVIAEVTGQAERLVAMGVPREGI  192

Query  215  LIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGV-DLTERLEGTLA  273
            L+DP HDFGKNTFHGL LLR + +LV TGWPVLMALSNKD VGETLGV ++TERLEGTLA
Sbjct  193  LVDPTHDFGKNTFHGLALLRRLDELVATGWPVLMALSNKDFVGETLGVAEVTERLEGTLA  252

Query  274  ATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            ATALAAAAGARMFR HEVA TRRV+EMVA+I G RPP RTVR LA
Sbjct  253  ATALAAAAGARMFRAHEVAETRRVVEMVAAIVGTRPPARTVRALA  297


>gi|54026711|ref|YP_120953.1| putative dihydropteroate synthase [Nocardia farcinica IFM 10152]
 gi|54018219|dbj|BAD59589.1| putative dihydropteroate synthase [Nocardia farcinica IFM 10152]
Length=313

 Score =  351 bits (901),  Expect = 8e-95, Method: Compositional matrix adjust.
 Identities = 205/313 (66%), Positives = 239/313 (77%), Gaps = 22/313 (7%)

Query  22   TPPALAGHSTLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADV  81
            +PPA A   TLCG+PVA DRAL+MAIVNRTPDSFYD+GATF+D AA  AV RAVA+GAD+
Sbjct  5    SPPA-APLPTLCGKPVATDRALVMAIVNRTPDSFYDRGATFTDEAAMAAVDRAVAEGADL  63

Query  82   IDVGGVKAGPGERVD--VDT---------------EITRLVPFIEWLRGAYPDQLISVDT  124
            +D+GGVKAGPG  VD  VD                E  R+VPF+  +R AYPD LISVDT
Sbjct  64   VDIGGVKAGPGSEVDAAVDIGGVKAGPGSEVDAAEETRRVVPFVAAIRAAYPDLLISVDT  123

Query  125  WRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGT  184
            WR++VA+AA A GADLINDTW G DP +  VAAE GAG+VC+HTGGA+PRTRP RV Y  
Sbjct  124  WRSEVARAAVAEGADLINDTWAGADPELVRVAAEHGAGIVCSHTGGAVPRTRPHRVRYAD  183

Query  185  TTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGW  244
                    V   V AAAERA AAGV  + +LIDP HDFGKNT+HGL LLR +  LV +GW
Sbjct  184  VVA----EVTETVVAAAERAAAAGVRTDSILIDPTHDFGKNTYHGLELLRGLDVLVNSGW  239

Query  245  PVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASI  304
            PVLMALSNKD +GETLGV L+ERLEGTLAATA +AAAGAR+FRVHEVA TRRV++M+A+I
Sbjct  240  PVLMALSNKDFIGETLGVGLSERLEGTLAATAWSAAAGARVFRVHEVAHTRRVVDMIAAI  299

Query  305  QGVRPPTRTVRGL  317
            QG+RPP RT+RGL
Sbjct  300  QGIRPPARTLRGL  312


>gi|262203200|ref|YP_003274408.1| dihydropteroate synthase [Gordonia bronchialis DSM 43247]
 gi|262086547|gb|ACY22515.1| dihydropteroate synthase [Gordonia bronchialis DSM 43247]
Length=293

 Score =  346 bits (887),  Expect = 3e-93, Method: Compositional matrix adjust.
 Identities = 202/288 (71%), Positives = 237/288 (83%), Gaps = 4/288 (1%)

Query  31   TLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAG  90
            TLCGRPVA DRAL+MAIVNRTPDSFYD+GA+F+D AA+  + + VA+GAD++D+GGVKAG
Sbjct  10   TLCGRPVATDRALVMAIVNRTPDSFYDRGASFADDAAQARIAQVVAEGADIVDIGGVKAG  69

Query  91   PGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDP  150
            PGE VD +TE  R+VP I W+R +YPD +ISVDTWRA+VA AACAAGADLINDTW G DP
Sbjct  70   PGEEVDAETEAARVVPMIGWIRESYPDLIISVDTWRAEVADAACAAGADLINDTWAGADP  129

Query  151  AMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVA  210
             +  VAA  GAG+VC+HTGGA  RTRP RV Y      +V  V++++  AAERA  AGVA
Sbjct  130  GLVSVAAARGAGIVCSHTGGATVRTRPHRVGYAD----IVGEVVAELGGAAERAAEAGVA  185

Query  211  REKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEG  270
            R+ ++IDP HDFGKNT HGL LLR V  LV TGWPVLMALSNKD VGETLGVDL +RLEG
Sbjct  186  RDSIVIDPTHDFGKNTHHGLALLRDVKVLVNTGWPVLMALSNKDFVGETLGVDLDQRLEG  245

Query  271  TLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            TLAATAL+AA GAR+FRVHEVAATRRV++MVA+I G+RPP RTVRGLA
Sbjct  246  TLAATALSAAHGARIFRVHEVAATRRVVDMVAAIAGIRPPARTVRGLA  293


>gi|72161718|ref|YP_289375.1| dihydropteroate synthase [Thermobifida fusca YX]
 gi|71915450|gb|AAZ55352.1| Dihydropteroate synthase [Thermobifida fusca YX]
Length=286

 Score =  340 bits (871),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 171/287 (60%), Positives = 211/287 (74%), Gaps = 4/287 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L  R    D+ L+MAIVNRTPDSFYD+GAT+ +  A D VH+ VA+GAD++D+GGVKA P
Sbjct  4    LGSRTFTDDQMLVMAIVNRTPDSFYDRGATWEEERALDRVHQVVAEGADIVDIGGVKAAP  63

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            GE + V  EI R+  F+  +R AYPD +ISVDTWRA+V +  C AGADL+ND WGG DPA
Sbjct  64   GEEIPVAEEIRRVAGFVAKVRDAYPDIVISVDTWRAEVGREVCQAGADLLNDAWGGYDPA  123

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            + EVAAEF  GLVC HTGG  PRTRP RV Y      VV + I    A AERAVA GV R
Sbjct  124  LAEVAAEFDVGLVCTHTGGVRPRTRPHRVHYD----DVVQSAIRDTVALAERAVALGVDR  179

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
             ++LIDPAHDFGK T H L + R + ++  TGWPVL++LSNKD VGETL + + ERL GT
Sbjct  180  SRILIDPAHDFGKTTRHSLEVTRRLNEMTATGWPVLVSLSNKDFVGETLDLPVEERLVGT  239

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LAATA+ A  GAR++RVH+V  TR+VL+MV+SI+G+R P+R VRGLA
Sbjct  240  LAATAVCAWHGARVYRVHQVVETRQVLDMVSSIKGLRAPSRAVRGLA  286


>gi|296138891|ref|YP_003646134.1| dihydropteroate synthase [Tsukamurella paurometabola DSM 20162]
 gi|296027025|gb|ADG77795.1| dihydropteroate synthase [Tsukamurella paurometabola DSM 20162]
Length=287

 Score =  339 bits (870),  Expect = 3e-91, Method: Compositional matrix adjust.
 Identities = 193/289 (67%), Positives = 222/289 (77%), Gaps = 4/289 (1%)

Query  30   STLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKA  89
            STLCGRPV  DRAL+MAI+NRTPDSFYD+G+ F+  AA D V  AVA+GAD++DVGGVKA
Sbjct  3    STLCGRPVPVDRALVMAIINRTPDSFYDRGSYFAVDAALDRVDAAVAEGADIVDVGGVKA  62

Query  90   GPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVD  149
            GPG+ VD   EI R VPFI  +R  +P  LISVDTWR+ VA+AA  AGADLINDTW G D
Sbjct  63   GPGQTVDAAEEIARTVPFIAQVRERHPQLLISVDTWRSSVAEAAVDAGADLINDTWAGAD  122

Query  150  PAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGV  209
              +P VAAE GAGLVC+HTGGA+PR+RP+RV Y      VV  V   + AAA+ A AAGV
Sbjct  123  RDLPRVAAETGAGLVCSHTGGAVPRSRPYRVRYPD----VVAEVRDHLVAAADAAYAAGV  178

Query  210  AREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLE  269
              + ++IDP HDFGKNT HGL LLRH+  LV TGWPVLMALSNKD +GETL   L ER+ 
Sbjct  179  REDGIVIDPTHDFGKNTHHGLALLRHLDALVDTGWPVLMALSNKDFIGETLDAGLEERVA  238

Query  270  GTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            GTLAATALAA  GARMFRVH+VA TRRV+EMVA+I G RPP R VRGLA
Sbjct  239  GTLAATALAARDGARMFRVHQVADTRRVIEMVAAIDGTRPPARVVRGLA  287


>gi|258652356|ref|YP_003201512.1| dihydropteroate synthase [Nakamurella multipartita DSM 44233]
 gi|258555581|gb|ACV78523.1| dihydropteroate synthase [Nakamurella multipartita DSM 44233]
Length=293

 Score =  333 bits (853),  Expect = 3e-89, Method: Compositional matrix adjust.
 Identities = 177/286 (62%), Positives = 207/286 (73%), Gaps = 4/286 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L GRP+  DRA +MAIVNRTPDSF+D GATF + AA +AV RAV +GAD++D+GGVKAG 
Sbjct  11   LRGRPLPADRAAVMAIVNRTPDSFFDAGATFGETAAMEAVRRAVDEGADLVDIGGVKAGV  70

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            G  V    EI R+VPF+  +R  +P+  ISVDTWRA VA AAC AGADLINDTW G DP 
Sbjct  71   GPEVTESDEIDRVVPFVARVRERFPELPISVDTWRAGVAVAACEAGADLINDTWAGADPD  130

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            +  VAA FGAG+VC+HTGGA PRT P+RVSY      VV AVI Q T AA R V  GV R
Sbjct  131  LAHVAARFGAGIVCSHTGGAAPRTNPYRVSYPD----VVAAVIEQTTTAARRMVELGVPR  186

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
              VLIDP HDFGKNT+H L L+    +LV TGWPVLMALSNKD VGETL + + +RLEGT
Sbjct  187  AGVLIDPTHDFGKNTWHSLELVHRTGELVATGWPVLMALSNKDFVGETLDLPVDQRLEGT  246

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGL  317
            LAATA+A   GA + R H+V ATRRV+EM A++ G R P    RGL
Sbjct  247  LAATAIAVWQGAAVVRAHQVRATRRVVEMAAAVAGTRAPLAPRRGL  292


>gi|134097619|ref|YP_001103280.1| dihydropteroate synthase [Saccharopolyspora erythraea NRRL 2338]
 gi|291010013|ref|ZP_06567986.1| dihydropteroate synthase [Saccharopolyspora erythraea NRRL 2338]
 gi|133910242|emb|CAM00355.1| dihydropteroate synthase [Saccharopolyspora erythraea NRRL 2338]
Length=289

 Score =  332 bits (850),  Expect = 6e-89, Method: Compositional matrix adjust.
 Identities = 175/279 (63%), Positives = 206/279 (74%), Gaps = 5/279 (1%)

Query  40   DRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAG-PGERVDVD  98
            DR L+MAIVNRT DSFYD+G TF  +AA +AV RAVADGAD++D+GGV+AG  GE VD  
Sbjct  14   DRPLVMAIVNRTRDSFYDRGRTFETSAAAEAVDRAVADGADIVDIGGVRAGAQGETVDAA  73

Query  99   TEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAE  158
             E  R+VPF+  +R  +P+ +ISVDTWR +VA+  C AGADL+NDTW G DP + EVAAE
Sbjct  74   EEARRVVPFVAAVRERHPELVISVDTWRHEVARHVCDAGADLLNDTWAGADPRLAEVAAE  133

Query  159  FGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDP  218
            FG G+VC+HTGG  PRT P RV Y      VV  V +++   AER V  GV    VLIDP
Sbjct  134  FGVGVVCSHTGGLPPRTDPHRVRYAD----VVAEVTAELVERAERMVRIGVPAHGVLIDP  189

Query  219  AHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALA  278
             HDFGKNT+HGL LLR V +LV TGWPVLMALSNKD VGETLG  + ERLEGTLAATA+A
Sbjct  190  THDFGKNTWHGLALLRRVDELVATGWPVLMALSNKDFVGETLGAGVDERLEGTLAATAVA  249

Query  279  AAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGL  317
            A  GAR+FR H V  TRRV+EMVASI G RPP + +R L
Sbjct  250  AWGGARVFRAHHVRETRRVVEMVASIAGTRPPAQVLRAL  288


>gi|256397046|ref|YP_003118610.1| dihydropteroate synthase [Catenulispora acidiphila DSM 44928]
 gi|256363272|gb|ACU76769.1| dihydropteroate synthase [Catenulispora acidiphila DSM 44928]
Length=312

 Score =  328 bits (841),  Expect = 7e-88, Method: Compositional matrix adjust.
 Identities = 166/279 (60%), Positives = 205/279 (74%), Gaps = 3/279 (1%)

Query  40   DRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDT  99
            D+ L+MAIVNRTPDSFYDKGATF+DAAA D V RA+++GAD+ID+GGVKAGPG+ VD+  
Sbjct  37   DQRLVMAIVNRTPDSFYDKGATFTDAAALDRVERALSEGADLIDIGGVKAGPGDAVDLAE  96

Query  100  EITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEF  159
            E  R+VPF+  +R  +P+ +ISVDTWRA+V  A CA GAD++ND WGG DP + EVAA  
Sbjct  97   ETRRVVPFVAEVRKRFPEAVISVDTWRAEVGDAVCAEGADVLNDAWGGWDPRLAEVAARH  156

Query  160  GAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPA  219
               LVC H GG  PRTRP RV Y      + D +   V   AERA A GV R+++LIDP 
Sbjct  157  AVALVCTHAGGVEPRTRPHRVGYADI---MADILERTVHGEAERAAALGVPRDRILIDPG  213

Query  220  HDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAA  279
            HDFGKNT H L   R +A++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A
Sbjct  214  HDFGKNTRHSLEATRRLAEMTATGWPVLVSLSNKDFVGETLNRPVKERLTGTLATTAVSA  273

Query  280  AAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
              GAR++RVHEVA TR+VLEMV++IQG+R P    RGLA
Sbjct  274  WLGARVYRVHEVAETRQVLEMVSAIQGLREPAVAKRGLA  312


>gi|257055201|ref|YP_003133033.1| Dihydropteroate synthase [Saccharomonospora viridis DSM 43017]
 gi|256585073|gb|ACU96206.1| Dihydropteroate synthase [Saccharomonospora viridis DSM 43017]
Length=288

 Score =  325 bits (834),  Expect = 5e-87, Method: Compositional matrix adjust.
 Identities = 178/284 (63%), Positives = 215/284 (76%), Gaps = 4/284 (1%)

Query  34   GRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGE  93
            GR V  +RAL+MAIVNRTPDSFYD+G+T+   AA  AV  AVADGAD++D+GGVKAGPG 
Sbjct  8    GRVVERNRALVMAIVNRTPDSFYDRGSTYDLDAALRAVDAAVADGADIVDIGGVKAGPGS  67

Query  94   RVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMP  153
             V V  EI R+VP +  +R  +PD LISVDTWR++V ++AC  GAD++NDTW   DPA+ 
Sbjct  68   EVSVAEEIRRVVPLVAAVRERHPDLLISVDTWRSEVGRSACEVGADILNDTWQSADPALA  127

Query  154  EVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREK  213
            EVAAEF AG VC+HTGGA PRT P RVSY      VV AVI +VT  AER  A GV R  
Sbjct  128  EVAAEFEAGYVCSHTGGAPPRTLPHRVSYP----DVVAAVIEEVTGRAERLAAMGVPRGG  183

Query  214  VLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLA  273
            +LIDP HDFGKNT+HGL LLR + +L  T WPVL+ALSNKD VGETLG +L +R++GTLA
Sbjct  184  ILIDPTHDFGKNTWHGLELLRRIRELTTTPWPVLLALSNKDFVGETLGAELHDRVDGTLA  243

Query  274  ATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGL  317
            ATA+AA  GA +FR HEV  TR+V++MVASI+G RPPT  +RGL
Sbjct  244  ATAVAAWEGAAVFRAHEVRRTRQVVDMVASIRGTRPPTLCLRGL  287


>gi|326381460|ref|ZP_08203154.1| dihydropteroate synthase [Gordonia neofelifaecis NRRL B-59395]
 gi|326199707|gb|EGD56887.1| dihydropteroate synthase [Gordonia neofelifaecis NRRL B-59395]
Length=292

 Score =  322 bits (826),  Expect = 4e-86, Method: Compositional matrix adjust.
 Identities = 198/289 (69%), Positives = 227/289 (79%), Gaps = 4/289 (1%)

Query  30   STLCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKA  89
            +TLCGRPVA DRAL+MAIVNRTPDSFYD+G+TFSD AA+  +   VA GAD+IDVGGVKA
Sbjct  8    ATLCGRPVATDRALVMAIVNRTPDSFYDRGSTFSDDAAKARIDEVVAQGADMIDVGGVKA  67

Query  90   GPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVD  149
            GPG  VD  TE  R+VP I W+R  +PD LISVDTWRA+VA  AC AGAD+INDTW GVD
Sbjct  68   GPGAEVDAATEAQRVVPMIAWIRRTHPDVLISVDTWRAEVAAEACEAGADMINDTWAGVD  127

Query  150  PAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGV  209
            PA+  VAA  GAG+VC+HTGGA  RTRP RV+Y          V+++V+ AA+RA  AGV
Sbjct  128  PALVSVAAAAGAGIVCSHTGGARVRTRPHRVAYDDVVA----DVVAEVSGAAQRARDAGV  183

Query  210  AREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLE  269
              + +LIDP HDFGKNT HGL LLRH+  LV TGWPVLMALSNKD +GETL  DL +R+ 
Sbjct  184  REDGILIDPTHDFGKNTHHGLALLRHLDRLVDTGWPVLMALSNKDFIGETLNADLDDRVA  243

Query  270  GTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            GTLAATALAAA GARMFRVHEVA TRRV++MVASI G RPP RTVRGLA
Sbjct  244  GTLAATALAAAQGARMFRVHEVADTRRVVDMVASIIGTRPPARTVRGLA  292


>gi|302536705|ref|ZP_07289047.1| dihydropteroate synthase [Streptomyces sp. C]
 gi|302445600|gb|EFL17416.1| dihydropteroate synthase [Streptomyces sp. C]
Length=286

 Score =  322 bits (824),  Expect = 6e-86, Method: Compositional matrix adjust.
 Identities = 165/276 (60%), Positives = 201/276 (73%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF D  A D V +AVA+GA +ID+GGVKAGPGE VD   E  
Sbjct  15   VIMAIVNRTPDSFYDQGATFRDEPALDRVEQAVAEGAAIIDIGGVKAGPGEHVDAAEEAR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R V F+  +R  +PD +ISVDTWR +V +A C AGAD++ND WGGVDP + EVAA +GAG
Sbjct  75   RTVGFVAEVRRRHPDVVISVDTWRHEVGEAVCEAGADVLNDAWGGVDPKLAEVAARYGAG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            +VC H GG  PRTRP R SY      V++ V+    A AERA A GV RE ++IDP HDF
Sbjct  135  IVCTHAGGVEPRTRPHRTSY----EDVMEDVLRVTVALAERAEALGVPRESIMIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R +A++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A  G
Sbjct  191  GKNTRHSLEATRRLAEMTETGWPVLVSLSNKDFVGETLDKPVKERLLGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            A+++RVHEVA T++VL+MV SIQG RPP    RGLA
Sbjct  251  AQVYRVHEVAETKQVLDMVRSIQGHRPPAVARRGLA  286


>gi|297157497|gb|ADI07209.1| dihydropteroate synthase [Streptomyces bingchenggensis BCW-1]
Length=286

 Score =  321 bits (823),  Expect = 8e-86, Method: Compositional matrix adjust.
 Identities = 168/287 (59%), Positives = 202/287 (71%), Gaps = 4/287 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L  R    +  +IMAIVNRTPDSFYD+GATF D  A D V +AVA+GA ++D+GGVKAGP
Sbjct  4    LGRREFGENEQVIMAIVNRTPDSFYDRGATFQDGPALDRVEQAVAEGAAIVDIGGVKAGP  63

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            GE V    E+ R V F+  +R  +PD +ISVDTWR +V +A C AGADL+ND WGGVDP 
Sbjct  64   GEEVSAAEEVRRTVGFVAEVRRRHPDVVISVDTWRHEVGEAVCGAGADLLNDAWGGVDPK  123

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            + EVAA +GAGLVC H GGA PRTRP RV+Y      VV  V+      A RAV  GV R
Sbjct  124  LAEVAARYGAGLVCTHAGGAQPRTRPHRVAYDD----VVADVLRVTLELARRAVELGVER  179

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
            E +LIDP HDFGKNT H L   R + +L  TGWPVL++LSNKD VGETL   + ERL GT
Sbjct  180  ESILIDPGHDFGKNTRHSLEATRRLGELAETGWPVLVSLSNKDFVGETLDRPVKERLLGT  239

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LA TA++A  GAR++RVHEVA TR+VL+MV+SI G RPP    RG+A
Sbjct  240  LATTAISAWLGARVYRVHEVAETRQVLDMVSSIAGHRPPAVARRGVA  286


>gi|295836669|ref|ZP_06823602.1| dihydropteroate synthase [Streptomyces sp. SPB74]
 gi|197699700|gb|EDY46633.1| dihydropteroate synthase [Streptomyces sp. SPB74]
Length=286

 Score =  321 bits (823),  Expect = 8e-86, Method: Compositional matrix adjust.
 Identities = 167/276 (61%), Positives = 202/276 (74%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF+D  A   V RAVA+GA +IDVGGVKAGPGE V  + E+ 
Sbjct  15   VIMAIVNRTPDSFYDQGATFADEPALTRVERAVAEGAAIIDVGGVKAGPGEEVSAEEEVR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R   F+  +R  +P+ +ISVDTWR +V +A CAAGADLIND WGGVDP + EVA  +GAG
Sbjct  75   RTAGFVAEVRRRFPEVVISVDTWRHEVGEAVCAAGADLINDAWGGVDPRLAEVAGRYGAG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            +VC H GGA PRTRP RV+Y      V+  ++   TA AERAV+ GV RE VLIDP HDF
Sbjct  135  IVCTHAGGARPRTRPHRVAY----EDVMADILRVTTALAERAVSLGVPRESVLIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R + ++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A  G
Sbjct  191  GKNTRHSLEATRRLPEMTATGWPVLVSLSNKDFVGETLDRPVKERLLGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            AR++RVHEVA TR++L+MVASI G R P    RGLA
Sbjct  251  ARVYRVHEVAETRQILDMVASIAGWREPAVARRGLA  286


>gi|333024607|ref|ZP_08452671.1| putative dihydropteroate synthase [Streptomyces sp. Tu6071]
 gi|332744459|gb|EGJ74900.1| putative dihydropteroate synthase [Streptomyces sp. Tu6071]
Length=286

 Score =  321 bits (822),  Expect = 1e-85, Method: Compositional matrix adjust.
 Identities = 167/276 (61%), Positives = 202/276 (74%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF+D  A   V RAVA+GA +IDVGGVKAGPGE V  + E+ 
Sbjct  15   VIMAIVNRTPDSFYDQGATFADEPALTRVERAVAEGAAIIDVGGVKAGPGEEVSAEEEVR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R   F+  +R  +P+ +ISVDTWR +V +A CAAGADLIND WGGVDP + EVA  +GAG
Sbjct  75   RTAGFVAEVRRRFPEVVISVDTWRHEVGEAVCAAGADLINDAWGGVDPRLAEVAGRYGAG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            +VC H GGA PRTRP RV+Y      V+  ++   TA AERAV+ GV RE VLIDP HDF
Sbjct  135  IVCTHAGGARPRTRPHRVAY----EDVMADILRVTTALAERAVSLGVPRESVLIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R + ++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A  G
Sbjct  191  GKNTRHSLESTRRLPEMAATGWPVLVSLSNKDFVGETLDRPVKERLLGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            AR++RVHEVA TR++L+MVASI G R P    RGLA
Sbjct  251  ARVYRVHEVAETRQILDMVASIAGWREPAVARRGLA  286


>gi|297202183|ref|ZP_06919580.1| dihydropteroate synthase [Streptomyces sviceus ATCC 29083]
 gi|197713622|gb|EDY57656.1| dihydropteroate synthase [Streptomyces sviceus ATCC 29083]
Length=286

 Score =  320 bits (819),  Expect = 3e-85, Method: Compositional matrix adjust.
 Identities = 169/276 (62%), Positives = 199/276 (73%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF D  A   V +AVA+GA +IDVGGVKAGPGE V    E  
Sbjct  15   VIMAIVNRTPDSFYDQGATFLDEPALARVEQAVAEGAAIIDVGGVKAGPGEEVSAAEEAR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R V F+  +R  +PD +ISVDTWRA V KA C AGADL+ND WGGVDP + EVAA +G G
Sbjct  75   RTVGFVAEVRRRFPDVIISVDTWRASVGKAVCEAGADLLNDAWGGVDPGLAEVAARYGVG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            LVC H GGA PRTRP RV+Y      V+  ++      AERAVA GV RE VLIDP HDF
Sbjct  135  LVCTHAGGAEPRTRPHRVTYDD----VMADILRVTVGLAERAVALGVPRESVLIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R + ++V TGWPVL++LSNKD VGETL   + ER+ GTLA TA++A  G
Sbjct  191  GKNTRHSLEATRRLGEMVETGWPVLVSLSNKDFVGETLDKPVKERVVGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            A+++RVHEVA TR+VL+MVASI G RPP    RGLA
Sbjct  251  AQVYRVHEVAETRQVLDMVASIAGRRPPAVARRGLA  286


>gi|302521755|ref|ZP_07274097.1| dihydropteroate synthase [Streptomyces sp. SPB78]
 gi|302430650|gb|EFL02466.1| dihydropteroate synthase [Streptomyces sp. SPB78]
Length=286

 Score =  319 bits (817),  Expect = 4e-85, Method: Compositional matrix adjust.
 Identities = 166/276 (61%), Positives = 201/276 (73%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF+D  A   V RAVA+GA +IDVGGVKAGPGE V  + E+ 
Sbjct  15   VIMAIVNRTPDSFYDQGATFADEPALTRVERAVAEGAAIIDVGGVKAGPGEEVSAEEEVR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R   F+  +R  +P+ +ISVDTWR +V +A CAAGADLIND WGGVDP + EVA  +G G
Sbjct  75   RTAGFVAEVRRRFPEVVISVDTWRHEVGEAVCAAGADLINDAWGGVDPRLAEVAGRYGVG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            +VC H GGA PRTRP RV+Y      V+  ++   TA AERAV+ GV RE VLIDP HDF
Sbjct  135  IVCTHAGGARPRTRPHRVAY----EDVMADILRVTTALAERAVSLGVPRESVLIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R + ++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A  G
Sbjct  191  GKNTRHSLEATRRLPEMTATGWPVLVSLSNKDFVGETLDRPVKERLLGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            AR++RVHEVA TR++L+MVASI G R P    RGLA
Sbjct  251  ARVYRVHEVAETRQILDMVASIAGWRDPAVARRGLA  286


>gi|337767981|emb|CCB76694.1| Dihydropteroate synthase 2 [Streptomyces cattleya NRRL 8057]
Length=286

 Score =  318 bits (814),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 168/287 (59%), Positives = 202/287 (71%), Gaps = 4/287 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L  R       +IMAIVNRTPDSFYD+GATF+D AA   V RAVA+GA +ID+GGVKAGP
Sbjct  4    LGKREFGDHEPVIMAIVNRTPDSFYDQGATFADEAALARVDRAVAEGAAIIDIGGVKAGP  63

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            GE V  + EI R+VPF+  +R  +PD +ISVDTWR +V +A CA GADL+ND WGGVDP 
Sbjct  64   GEEVTTEEEIRRIVPFVAEVRERHPDVVISVDTWRHEVGEAVCAVGADLLNDAWGGVDPH  123

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            + EVAA    GLVC H GGA PRTRP RV Y      V+  ++      A+RA   GV R
Sbjct  124  LAEVAARHRVGLVCTHAGGAEPRTRPHRVGY----EDVMADILRVTLGLAQRAAELGVPR  179

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
            + +LIDP HDFGKNT H L   R + ++V TGWPVL++LSNKD VGETL   + ERL GT
Sbjct  180  DAILIDPGHDFGKNTRHSLEATRRLGEMVGTGWPVLVSLSNKDFVGETLDRPVKERLLGT  239

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LA TA++A  GAR++RVHEVA TR+VL+MVASI G RPP    RGLA
Sbjct  240  LATTAVSAWLGARVYRVHEVAETRQVLDMVASIAGHRPPAVARRGLA  286


>gi|333921013|ref|YP_004494594.1| putative dihydropteroate synthase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333483234|gb|AEF41794.1| Putative dihydropteroate synthase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=247

 Score =  317 bits (812),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 168/250 (68%), Positives = 197/250 (79%), Gaps = 4/250 (1%)

Query  69   DAVHRAVADGADVIDVGGVKAGPGERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQ  128
            +AV R+V +GADVID+GGVKAGPG+ VD   E+ R+VPF+  +R  +PD +IS+DTWRA 
Sbjct  2    EAVRRSVNEGADVIDIGGVKAGPGQDVDEAEEMRRVVPFVAAVRNTFPDVIISIDTWRAN  61

Query  129  VAKAACAAGADLINDTWGGVDPAMPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRG  188
            VA+ ACA GADLINDTW G DP +  VAAE GAG+VC+HTGGA PRTRP RV Y      
Sbjct  62   VARRACAEGADLINDTWAGADPELAVVAAELGAGIVCSHTGGAEPRTRPHRVRYADIAAE  121

Query  189  VVDAVISQVTAAAERAVAAGVAREKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLM  248
            V D    +VT AA+RA++AGV  + +LIDP HDFGKNTFHGL LLR +  LV +GWPVLM
Sbjct  122  VAD----EVTRAADRALSAGVREDGILIDPTHDFGKNTFHGLDLLRRLDVLVNSGWPVLM  177

Query  249  ALSNKDVVGETLGVDLTERLEGTLAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVR  308
            ALSNKD +GETL V LTERLEGTLAATA+AA +GARMFRVHEVA TRRVL+MVA+I G R
Sbjct  178  ALSNKDFIGETLDVGLTERLEGTLAATAVAAWSGARMFRVHEVAQTRRVLDMVAAIAGTR  237

Query  309  PPTRTVRGLA  318
            PP RTVRGLA
Sbjct  238  PPARTVRGLA  247


>gi|318058423|ref|ZP_07977146.1| dihydropteroate synthase [Streptomyces sp. SA3_actG]
Length=286

 Score =  317 bits (812),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 165/276 (60%), Positives = 201/276 (73%), Gaps = 4/276 (1%)

Query  43   LIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGPGERVDVDTEIT  102
            +IMAIVNRTPDSFYD+GATF+D  A   V RAVA+GA +IDVGGVKAGPGE V  + E+ 
Sbjct  15   VIMAIVNRTPDSFYDQGATFADEPALMRVERAVAEGAAIIDVGGVKAGPGEEVSAEEEVR  74

Query  103  RLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPAMPEVAAEFGAG  162
            R   F+  +R  +P+ +ISVDTWR +V +A CAAGADLIND WGGVDP + EVA  +G G
Sbjct  75   RTAGFVAEVRRRFPEVVISVDTWRHEVGEAVCAAGADLINDAWGGVDPRLAEVAGRYGVG  134

Query  163  LVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAREKVLIDPAHDF  222
            +VC H GGA PRTRP RV+Y      V+  ++   TA AERAV+ GV RE VLIDP HDF
Sbjct  135  IVCTHAGGARPRTRPHRVAY----EDVMADILRVTTALAERAVSLGVPRESVLIDPGHDF  190

Query  223  GKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGTLAATALAAAAG  282
            GKNT H L   R + ++  TGWPVL++LSNKD VGETL   + ERL GTLA TA++A  G
Sbjct  191  GKNTRHSLEATRRLPEMAATGWPVLVSLSNKDFVGETLDRPVKERLLGTLATTAVSAWLG  250

Query  283  ARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            A+++RVHEVA TR++L+MVASI G R P    RGLA
Sbjct  251  AQVYRVHEVAETRQILDMVASIAGWREPAVARRGLA  286


>gi|297560205|ref|YP_003679179.1| dihydropteroate synthase [Nocardiopsis dassonvillei subsp. dassonvillei 
DSM 43111]
 gi|296844653|gb|ADH66673.1| dihydropteroate synthase [Nocardiopsis dassonvillei subsp. dassonvillei 
DSM 43111]
Length=286

 Score =  317 bits (811),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 165/286 (58%), Positives = 201/286 (71%), Gaps = 4/286 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L GR    D  L+MAIVNRTPDSFYD GAT+ D  A + V R VA+GAD++D+GGV AG 
Sbjct  4    LRGREYDADTTLVMAIVNRTPDSFYDSGATWDDGPAFERVRRVVAEGADIVDIGGVTAGY  63

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            G+ VD D E  R+V F+  +R  +P  +ISVDTWRA V +A C AGADL+ND WGG DP 
Sbjct  64   GQPVDADEEKRRVVDFVAAVRAEFPQLVISVDTWRASVGRAVCEAGADLLNDAWGGYDPE  123

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            + EVAAEF A LVC HTGG  PRT P R  Y    R  V+  +    A AERAV+ GV  
Sbjct  124  LAEVAAEFDAALVCTHTGGVAPRTPPHRTRYEDVVRSAVEDTV----ALAERAVSLGVHP  179

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
               +IDPAHDFGKNT+H L L R + ++  TG PVL++LSNK+ VGETL + + ERL GT
Sbjct  180  ASAIIDPAHDFGKNTWHSLELTRRLDEMTATGRPVLVSLSNKNFVGETLDLPVGERLTGT  239

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGL  317
            LAATA+ A  GA+++RVHEVA TR+ L+MVASI+GVRPP R VRGL
Sbjct  240  LAATAVCAWHGAQVYRVHEVAQTRQTLDMVASIRGVRPPARAVRGL  285


>gi|29829665|ref|NP_824299.1| dihydropteroate synthase [Streptomyces avermitilis MA-4680]
 gi|29606773|dbj|BAC70834.1| putative dihydropteroate synthase [Streptomyces avermitilis MA-4680]
Length=286

 Score =  316 bits (810),  Expect = 3e-84, Method: Compositional matrix adjust.
 Identities = 166/287 (58%), Positives = 201/287 (71%), Gaps = 4/287 (1%)

Query  32   LCGRPVAGDRALIMAIVNRTPDSFYDKGATFSDAAARDAVHRAVADGADVIDVGGVKAGP  91
            L  R       +IMAIVNRTPDSFYD+GATF D AA   V RAV++GA +ID+GGVKAGP
Sbjct  4    LGKREFGTHEPVIMAIVNRTPDSFYDQGATFHDEAALARVERAVSEGAAIIDIGGVKAGP  63

Query  92   GERVDVDTEITRLVPFIEWLRGAYPDQLISVDTWRAQVAKAACAAGADLINDTWGGVDPA  151
            GE V  + E  R V F+  +R  +PD +ISVDTWR +V  A C AGADL+ND WGGVDP 
Sbjct  64   GEEVTAEEEARRTVGFVAEVRRRHPDVIISVDTWRHEVGAAVCEAGADLLNDAWGGVDPR  123

Query  152  MPEVAAEFGAGLVCAHTGGALPRTRPFRVSYGTTTRGVVDAVISQVTAAAERAVAAGVAR  211
            + EVAA +G GLVC H GG+ PRTRP R++Y      V+  ++      AERAV  GV R
Sbjct  124  LAEVAARYGVGLVCTHAGGSQPRTRPHRIAYDD----VMADILGVTLGLAERAVELGVPR  179

Query  212  EKVLIDPAHDFGKNTFHGLLLLRHVADLVMTGWPVLMALSNKDVVGETLGVDLTERLEGT  271
            E VLIDP HDFGKNT H L   R + ++V TGWPVL++LSNKD VGETL   + ER+ GT
Sbjct  180  ESVLIDPGHDFGKNTRHSLEATRRLGEMVETGWPVLVSLSNKDFVGETLDKPVKERVLGT  239

Query  272  LAATALAAAAGARMFRVHEVAATRRVLEMVASIQGVRPPTRTVRGLA  318
            LA TA++A  GA+++RVHEVA TR+VL+MVASI G RPP    RGLA
Sbjct  240  LATTAVSAWLGAQVYRVHEVAETRQVLDMVASIAGHRPPAVARRGLA  286



Lambda     K      H
   0.320    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 555428799294


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40