BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv1225c
Length=276
Score E
Sequences producing significant alignments: (Bits) Value
gi|15608365|ref|NP_215741.1| hypothetical protein Rv1225c [Mycob... 555 2e-156
gi|289573884|ref|ZP_06454111.1| conserved hypothetical protein [... 555 3e-156
gi|308231783|ref|ZP_07413731.2| hypothetical protein TMAG_01856 ... 552 2e-155
gi|298524725|ref|ZP_07012134.1| HAD-superfamily hydrolase [Mycob... 495 2e-138
gi|289761370|ref|ZP_06520748.1| conserved hypothetical protein [... 487 7e-136
gi|120401771|ref|YP_951600.1| HAD family hydrolase [Mycobacteriu... 373 2e-101
gi|108797579|ref|YP_637776.1| HAD family hydrolase [Mycobacteriu... 371 5e-101
gi|118471392|ref|YP_885269.1| hydrolase [Mycobacterium smegmatis... 368 7e-100
gi|145220752|ref|YP_001131430.1| Fis family transcriptional regu... 346 2e-93
gi|169627744|ref|YP_001701393.1| HAD-superfamily hydrolase [Myco... 323 2e-86
gi|289744970|ref|ZP_06504348.1| hydrolase [Mycobacterium tubercu... 295 4e-78
gi|111019141|ref|YP_702113.1| hydrolase [Rhodococcus jostii RHA1... 287 1e-75
gi|343925496|ref|ZP_08765015.1| putative hydrolase [Gordonia alk... 284 1e-74
gi|226361279|ref|YP_002779057.1| hydrolase [Rhodococcus opacus B... 283 2e-74
gi|226305013|ref|YP_002764971.1| hypothetical protein RER_15240 ... 275 8e-72
gi|229490168|ref|ZP_04384015.1| transcriptional regulator, Fis f... 274 1e-71
gi|262200688|ref|YP_003271896.1| HAD-superfamily hydrolase [Gord... 271 6e-71
gi|325673979|ref|ZP_08153669.1| inorganic pyrophosphatase [Rhodo... 268 8e-70
gi|312141192|ref|YP_004008528.1| haloacid dehalogenase-like hydr... 267 1e-69
gi|15321582|gb|AAK95491.1|AF233387_3 unknown [Rhodococcus equi] 267 1e-69
gi|289757323|ref|ZP_06516701.1| LOW QUALITY PROTEIN: predicted p... 265 8e-69
gi|312200039|ref|YP_004020100.1| HAD-superfamily hydrolase, subf... 249 2e-64
gi|294994782|ref|ZP_06800473.1| hypothetical protein Mtub2_09787... 248 5e-64
gi|29828745|ref|NP_823379.1| hydrolase [Streptomyces avermitilis... 246 4e-63
gi|333918245|ref|YP_004491826.1| putative hydrolase [Amycolicico... 244 2e-62
gi|302555585|ref|ZP_07307927.1| hydrolase [Streptomyces viridoch... 243 2e-62
gi|297203917|ref|ZP_06921314.1| hydrolase [Streptomyces sviceus ... 230 2e-58
gi|111221102|ref|YP_711896.1| putative hydrolase [Frankia alni A... 229 3e-58
gi|320010759|gb|ADW05609.1| HAD-superfamily hydrolase, subfamily... 223 3e-56
gi|134102052|ref|YP_001107713.1| HAD superfamily hydrolase [Sacc... 218 5e-55
gi|221635864|ref|YP_002523740.1| HAD-superfamily subfamily IIA h... 209 4e-52
gi|116753965|ref|YP_843083.1| HAD family hydrolase [Methanosaeta... 168 7e-40
gi|91775199|ref|YP_544955.1| HAD family hydrolase [Methylobacill... 166 3e-39
gi|253996501|ref|YP_003048565.1| HAD-superfamily subfamily IIA h... 162 7e-38
gi|24217163|ref|NP_714646.1| phospholysine phosphohistidine inor... 161 1e-37
gi|45655662|ref|YP_003471.1| haloacid dehalogenase-like protein ... 159 4e-37
gi|334109499|ref|ZP_08483778.1| HAD-superfamily subfamily IIA hy... 158 7e-37
gi|192360525|ref|YP_001983356.1| HAD-superfamily hydrolase [Cell... 157 1e-36
gi|297537265|ref|YP_003673034.1| HAD-superfamily subfamily IIA h... 157 1e-36
gi|114321702|ref|YP_743385.1| HAD family hydrolase [Alkalilimnic... 155 6e-36
gi|116332521|ref|YP_802238.1| sugar phosphatase [Leptospira borg... 153 3e-35
gi|307353415|ref|YP_003894466.1| HAD-superfamily subfamily IIA h... 152 4e-35
gi|114776581|ref|ZP_01451626.1| haloacid dehalogenase-like prote... 151 1e-34
gi|268317966|ref|YP_003291685.1| HAD-superfamily subfamily IIA h... 150 2e-34
gi|253999927|ref|YP_003051990.1| HAD-superfamily subfamily IIA h... 150 2e-34
gi|313201900|ref|YP_004040558.1| had-superfamily subfamily iia h... 150 2e-34
gi|53804785|ref|YP_113604.1| HAD superfamily hydrolase [Methyloc... 149 3e-34
gi|345131096|gb|EGW61998.1| HAD-superfamily subfamily IIA hydrol... 147 2e-33
gi|116329636|ref|YP_799355.1| sugar phosphatase [Leptospira borg... 147 3e-33
gi|71737277|ref|YP_276422.1| HAD superfamily hydrolase [Pseudomo... 145 5e-33
>gi|15608365|ref|NP_215741.1| hypothetical protein Rv1225c [Mycobacterium tuberculosis H37Rv]
gi|15840669|ref|NP_335706.1| HAD superfamily hydrolase [Mycobacterium tuberculosis CDC1551]
gi|31792418|ref|NP_854911.1| hypothetical protein Mb1257c [Mycobacterium bovis AF2122/97]
39 more sequence titles
Length=276
Score = 555 bits (1431), Expect = 2e-156, Method: Compositional matrix adjust.
Identities = 275/276 (99%), Positives = 276/276 (100%), Gaps = 0/276 (0%)
Query 1 VDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
+DVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA
Sbjct 1 MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
Query 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED
Sbjct 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
Query 121 CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG 180
CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG
Sbjct 121 CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG 180
Query 181 MEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT 240
MEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT
Sbjct 181 MEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT 240
Query 241 GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC
Sbjct 241 GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
>gi|289573884|ref|ZP_06454111.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
gi|339631292|ref|YP_004722934.1| hypothetical protein MAF_12440 [Mycobacterium africanum GM041182]
gi|289538315|gb|EFD42893.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
gi|339330648|emb|CCC26316.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
Length=276
Score = 555 bits (1430), Expect = 3e-156, Method: Compositional matrix adjust.
Identities = 274/276 (99%), Positives = 276/276 (100%), Gaps = 0/276 (0%)
Query 1 VDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
+DVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA
Sbjct 1 MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
Query 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED
Sbjct 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
Query 121 CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG 180
CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG
Sbjct 121 CPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTG 180
Query 181 MEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT 240
MEQACGKTATAIGKPA+EGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT
Sbjct 181 MEQACGKTATAIGKPASEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRT 240
Query 241 GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC
Sbjct 241 GKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
>gi|308231783|ref|ZP_07413731.2| hypothetical protein TMAG_01856 [Mycobacterium tuberculosis SUMu001]
gi|308370021|ref|ZP_07420033.2| hypothetical protein TMBG_01383 [Mycobacterium tuberculosis SUMu002]
gi|308370662|ref|ZP_07422266.2| hypothetical protein TMCG_00854 [Mycobacterium tuberculosis SUMu003]
22 more sequence titles
Length=274
Score = 552 bits (1422), Expect = 2e-155, Method: Compositional matrix adjust.
Identities = 273/274 (99%), Positives = 274/274 (100%), Gaps = 0/274 (0%)
Query 3 VAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALG 62
+AHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALG
Sbjct 1 MAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALG 60
Query 63 AAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCP 122
AAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCP
Sbjct 61 AAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCP 120
Query 123 EAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGME 182
EAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGME
Sbjct 121 EAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGME 180
Query 183 QACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGK 242
QACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGK
Sbjct 181 QACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGK 240
Query 243 FRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
FRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC
Sbjct 241 FRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 274
>gi|298524725|ref|ZP_07012134.1| HAD-superfamily hydrolase [Mycobacterium tuberculosis 94_M4241A]
gi|298494519|gb|EFI29813.1| HAD-superfamily hydrolase [Mycobacterium tuberculosis 94_M4241A]
Length=244
Score = 495 bits (1275), Expect = 2e-138, Method: Compositional matrix adjust.
Identities = 243/244 (99%), Positives = 244/244 (100%), Gaps = 0/244 (0%)
Query 33 VRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGAR 92
+RQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGAR
Sbjct 1 MRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGAR 60
Query 93 CFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDG 152
CFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDG
Sbjct 61 CFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDG 120
Query 153 VPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQ 212
VPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQ
Sbjct 121 VPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQ 180
Query 213 QMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPP 272
QMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPP
Sbjct 181 QMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPP 240
Query 273 LLGC 276
LLGC
Sbjct 241 LLGC 244
>gi|289761370|ref|ZP_06520748.1| conserved hypothetical protein [Mycobacterium tuberculosis GM
1503]
gi|289708876|gb|EFD72892.1| conserved hypothetical protein [Mycobacterium tuberculosis GM
1503]
Length=254
Score = 487 bits (1254), Expect = 7e-136, Method: Compositional matrix adjust.
Identities = 239/239 (100%), Positives = 239/239 (100%), Gaps = 0/239 (0%)
Query 38 HRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVN 97
HRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVN
Sbjct 16 HRGIACAYLTNTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVN 75
Query 98 NGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVA 157
NGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVA
Sbjct 76 NGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVYGWMLDGVPVVA 135
Query 158 MHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMI 217
MHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMI
Sbjct 136 MHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPAAEGFLAAADRVGVDPQQMVMI 195
Query 218 GDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 276
GDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC
Sbjct 196 GDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLAGASATRPHHVIDSVAGLPPLLGC 254
>gi|120401771|ref|YP_951600.1| HAD family hydrolase [Mycobacterium vanbaalenii PYR-1]
gi|119954589|gb|ABM11594.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium vanbaalenii
PYR-1]
Length=271
Score = 373 bits (957), Expect = 2e-101, Method: Compositional matrix adjust.
Identities = 184/265 (70%), Positives = 211/265 (80%), Gaps = 0/265 (0%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ IPGAAET+R L IACAYLTNTTTRTR QIA+ L AG+ V A
Sbjct 6 VLFDIDGVLVTSWKPIPGAAETLRTLADNQIACAYLTNTTTRTRVQIADLLTEAGMAVRA 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
D+VITA VLTA+Y+ YP ARCFLVN+G I ED+PGID+V S+E P+APDVV+L
Sbjct 66 DEVITAAVLTADYVRDRYPDARCFLVNSGQIGEDMPGIDLVYSSEFSGPRAPDAPDVVLL 125
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP++ H TLS VY WM GVPVVAMHR+ W TTDGLRIDTGMYL GMEQ G+ AT
Sbjct 126 GGAGPEYSHLTLSWVYDWMAQGVPVVAMHRSTAWTTTDGLRIDTGMYLIGMEQTSGRKAT 185
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKPA EGFL+AA R+GVDP++M M+GDDL+NDVLAAQ VGM+GVLVRTGKFRQ TLDR
Sbjct 186 AVGKPAPEGFLSAAARLGVDPEEMYMVGDDLNNDVLAAQVVGMSGVLVRTGKFRQDTLDR 245
Query 251 WLAGASATRPHHVIDSVAGLPPLLG 275
W A A +P+HVIDSVA P LLG
Sbjct 246 WAADEFAMQPNHVIDSVADFPALLG 270
>gi|108797579|ref|YP_637776.1| HAD family hydrolase [Mycobacterium sp. MCS]
gi|119866666|ref|YP_936618.1| HAD family hydrolase [Mycobacterium sp. KMS]
gi|126433202|ref|YP_001068893.1| HAD family hydrolase [Mycobacterium sp. JLS]
gi|108767998|gb|ABG06720.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. MCS]
gi|119692755|gb|ABL89828.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. KMS]
gi|126233002|gb|ABN96402.1| HAD-superfamily hydrolase, subfamily IIA [Mycobacterium sp. JLS]
Length=271
Score = 371 bits (953), Expect = 5e-101, Method: Compositional matrix adjust.
Identities = 184/266 (70%), Positives = 214/266 (81%), Gaps = 0/266 (0%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SWR I GAAE +R L+ IA +YLTNTTT+TRRQIA+ L AG+ V A
Sbjct 6 VLFDIDGVLVTSWRPIDGAAEALRVLSDHQIARSYLTNTTTKTRRQIADLLVDAGMAVTA 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
D+VITA VLTAEY+ YPGARCFLVN+G I ED+PG+D+V + E GP+ PE PDVV+L
Sbjct 66 DEVITAAVLTAEYVRDRYPGARCFLVNSGRIGEDMPGVDLVYAGEFGPDHVPETPDVVLL 125
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP++DH TLS VY WM GVPVVAMHR+ +WNT DGLRIDTGMYL GME+ G+ AT
Sbjct 126 GGAGPEYDHLTLSWVYDWMARGVPVVAMHRSTSWNTADGLRIDTGMYLIGMEETSGRKAT 185
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKPA EGFLAAA R+GVDP++M ++GDDL+NDVLA Q VGMTGVLVRTGKFRQ TLDR
Sbjct 186 AVGKPAPEGFLAAAGRLGVDPEEMYIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQDTLDR 245
Query 251 WLAGASATRPHHVIDSVAGLPPLLGC 276
W A A +P+HVIDSVA LP LLG
Sbjct 246 WAADEFAMQPNHVIDSVADLPGLLGL 271
>gi|118471392|ref|YP_885269.1| hydrolase [Mycobacterium smegmatis str. MC2 155]
gi|118172679|gb|ABK73575.1| hydrolase [Mycobacterium smegmatis str. MC2 155]
Length=271
Score = 368 bits (944), Expect = 7e-100, Method: Compositional matrix adjust.
Identities = 183/266 (69%), Positives = 211/266 (80%), Gaps = 0/266 (0%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ I GAA+T+R L IA +YLTNTTT+TR QIAE L AAG+ V+
Sbjct 6 VLFDIDGVLVTSWQPIEGAAQTLRVLADNQIARSYLTNTTTKTRVQIAELLTAAGMDVSP 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
D+VITA VLTAEY+ +PGARCFLVN+G I ED+PG+DVV S+E PEAPDVV+L
Sbjct 66 DEVITAAVLTAEYVRDRFPGARCFLVNSGRIDEDMPGVDVVYSSEFSGPRAPEAPDVVLL 125
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP++ H TLS VY WM GVPVVAMHR+ +W TTDGLR+DTGMYL GME+ G+ AT
Sbjct 126 GGAGPEYSHLTLSWVYDWMAQGVPVVAMHRSTSWTTTDGLRVDTGMYLIGMEETSGRKAT 185
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKPA EGFLAAA R+GVDP +M MIGDDL+NDVLAAQ VGMTGVLVRTGKFRQ LDR
Sbjct 186 AVGKPAPEGFLAAASRLGVDPDEMYMIGDDLNNDVLAAQVVGMTGVLVRTGKFRQSVLDR 245
Query 251 WLAGASATRPHHVIDSVAGLPPLLGC 276
W A A +P+HVIDSVA LP LLG
Sbjct 246 WAADDFAMQPNHVIDSVADLPALLGL 271
>gi|145220752|ref|YP_001131430.1| Fis family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|315442295|ref|YP_004075174.1| sugar phosphatase of HAD superfamily [Mycobacterium sp. Spyr1]
gi|145213238|gb|ABP42642.1| transcriptional regulator, Fis family [Mycobacterium gilvum PYR-GCK]
gi|315260598|gb|ADT97339.1| predicted sugar phosphatase of HAD superfamily [Mycobacterium
sp. Spyr1]
Length=271
Score = 346 bits (888), Expect = 2e-93, Method: Compositional matrix adjust.
Identities = 179/265 (68%), Positives = 208/265 (79%), Gaps = 0/265 (0%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ IPGAAET+R L IAC YLTNTTTRTR QIA+ L AG+ V A
Sbjct 6 VLFDIDGVLVTSWKPIPGAAETLRTLADNQIACTYLTNTTTRTRSQIADLLTEAGMAVRA 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
D+VITA VLTA+Y+ YP ARCFLVN+G I ED+PGID+V S+E PE PDVV+L
Sbjct 66 DEVITAAVLTADYVRDRYPDARCFLVNSGQIAEDMPGIDIVYSSEFTGPRAPERPDVVLL 125
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP++ H TLS VY WM GVPVVAMHR+ W T DGLR+DTGMYL GMEQ G+ A
Sbjct 126 GGAGPEYSHLTLSWVYDWMAQGVPVVAMHRSTAWTTVDGLRVDTGMYLIGMEQTSGRKAA 185
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKPA EGFL+AA+R+GVDP++M ++GDDL+NDVLA Q VGMTGVLVRTGKFRQ TLDR
Sbjct 186 AVGKPAPEGFLSAANRLGVDPEEMFIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQDTLDR 245
Query 251 WLAGASATRPHHVIDSVAGLPPLLG 275
W A A +P+HVIDS+A LP LLG
Sbjct 246 WAADEFAMQPNHVIDSIADLPALLG 270
>gi|169627744|ref|YP_001701393.1| HAD-superfamily hydrolase [Mycobacterium abscessus ATCC 19977]
gi|169239711|emb|CAM60739.1| Putative HAD-superfamily hydrolase [Mycobacterium abscessus]
Length=265
Score = 323 bits (827), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 162/264 (62%), Positives = 198/264 (75%), Gaps = 7/264 (2%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW I GAA+ ++ L + I +LTNTT+RTR QIAE L AAG+ V A
Sbjct 6 VLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPA 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
D+VITA +LTA+++ +PGARC+L+N+GDIT D+ G+D V E + PDV++L
Sbjct 66 DEVITAAMLTADHVITQHPGARCYLLNDGDITADMAGVDFV-------ESLSDDPDVIIL 118
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGPQFDH LSRVY M G+PVVAMHRN W+T +GLR+DTG+YL GMEQ G+ A
Sbjct 119 GGAGPQFDHVALSRVYELMAQGIPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAV 178
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKPA GF AA+R+G +P Q+VM+GDDLH DVLAAQ VGMTGVLVRTGKFRQ TLDR
Sbjct 179 AVGKPAPAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQDTLDR 238
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
W A A +P +V+DSVA LPPLL
Sbjct 239 WAADQYAMQPAYVVDSVADLPPLL 262
>gi|289744970|ref|ZP_06504348.1| hydrolase [Mycobacterium tuberculosis 02_1987]
gi|289685498|gb|EFD52986.1| hydrolase [Mycobacterium tuberculosis 02_1987]
gi|339294212|gb|AEJ46323.1| hypothetical protein CCDC5079_1133 [Mycobacterium tuberculosis
CCDC5079]
gi|339297852|gb|AEJ49962.1| hypothetical protein CCDC5180_1125 [Mycobacterium tuberculosis
CCDC5180]
Length=145
Score = 295 bits (756), Expect = 4e-78, Method: Compositional matrix adjust.
Identities = 143/143 (100%), Positives = 143/143 (100%), Gaps = 0/143 (0%)
Query 134 GPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIG 193
GPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIG
Sbjct 3 GPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIG 62
Query 194 KPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLA 253
KPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLA
Sbjct 63 KPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDRWLA 122
Query 254 GASATRPHHVIDSVAGLPPLLGC 276
GASATRPHHVIDSVAGLPPLLGC
Sbjct 123 GASATRPHHVIDSVAGLPPLLGC 145
>gi|111019141|ref|YP_702113.1| hydrolase [Rhodococcus jostii RHA1]
gi|110818671|gb|ABG93955.1| possible hydrolase [Rhodococcus jostii RHA1]
Length=259
Score = 287 bits (734), Expect = 1e-75, Method: Compositional matrix adjust.
Identities = 153/264 (58%), Positives = 183/264 (70%), Gaps = 15/264 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL DIDGVLV SW I GAA VR++ RG+ACAYLTNTT+RT +IA+AL +AGI +
Sbjct 7 VLLDIDGVLVTSWHPIDGAAAAVREVRERGLACAYLTNTTSRTCDEIADALRSAGIEADS 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+++TA LTAEY+ YPGAR +++N+GDI DL GI E+ ED P+VV+L
Sbjct 67 GEIVTAARLTAEYVRSTYPGARAWVLNSGDIVADLSGI------ELDDED----PEVVIL 116
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV MLDGVPVVAMHR TW T DGLRIDTG YL GME+ G
Sbjct 117 GGAGPEFTHDALSRVVELMLDGVPVVAMHRATTWATHDGLRIDTGTYLPGMEEVAGTNVV 176
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
++GKP+ FL A D +G +P VM+GDDL NDVLAAQ VG+TGVLVRTGKFRQ LD
Sbjct 177 SVGKPSLAAFLTATDLMGTEPDVTVMVGDDLTNDVLAAQRVGLTGVLVRTGKFRQSVLD- 235
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+ RP HV+DSVA LP LL
Sbjct 236 ----LAPQRPDHVVDSVAQLPKLL 255
>gi|343925496|ref|ZP_08765015.1| putative hydrolase [Gordonia alkanivorans NBRC 16433]
gi|343764588|dbj|GAA11941.1| putative hydrolase [Gordonia alkanivorans NBRC 16433]
Length=266
Score = 284 bits (727), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 143/268 (54%), Positives = 184/268 (69%), Gaps = 8/268 (2%)
Query 7 MAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGI 66
MA +L DIDGV+V SW+A+PGA E V +L R I +LTNTT+R+R +IAE L G
Sbjct 1 MALGLLLDIDGVMVTSWKALPGAVEAVSRLADRKIPRMFLTNTTSRSRNEIAELLNDCGF 60
Query 67 PVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPD 126
V AD+++TA LTAEY+ +PG R +++N G I ED+ G+++ D P +
Sbjct 61 FVDADEILTAAKLTAEYVGSTFPGKRVWVLNQGPIAEDMTGVELT--------DDPADAE 112
Query 127 VVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACG 186
VVVLG AGP F H LS+V +LDGVPV+AMHR+MTW+T DGL IDTG+YL G+E+A G
Sbjct 113 VVVLGGAGPVFTHDALSKVLEMLLDGVPVIAMHRSMTWSTADGLSIDTGVYLEGLEKASG 172
Query 187 KTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ 246
K AIGKP+ GF AA D +G++P Q+VM+GDD+HNDVL AQA + GVLVRTGKFR++
Sbjct 173 KKIKAIGKPSPLGFRAATDMLGLEPNQVVMVGDDMHNDVLGAQASALIGVLVRTGKFREE 232
Query 247 TLDRWLAGASATRPHHVIDSVAGLPPLL 274
LD P HVIDSVA LP L+
Sbjct 233 ALDALARDEFGPFPDHVIDSVADLPELI 260
>gi|226361279|ref|YP_002779057.1| hydrolase [Rhodococcus opacus B4]
gi|226239764|dbj|BAH50112.1| putative hydrolase [Rhodococcus opacus B4]
Length=259
Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust.
Identities = 151/264 (58%), Positives = 184/264 (70%), Gaps = 15/264 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL DIDGVLV SW I GAA VR++ RG+ACAYLTNTT+RT +IA+AL +AGI +
Sbjct 7 VLLDIDGVLVTSWHPIDGAAAAVREVRERGLACAYLTNTTSRTCDEIADALRSAGIEADS 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+++TA LTAEY+ YPG+R +++N+GDIT DL GI++ +D E P+VV+L
Sbjct 67 GEIVTAARLTAEYVRSTYPGSRAWVLNSGDITADLSGIEL--------DD--ENPEVVIL 116
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV MLDGVPVVAMHR TW T DGLRIDTG YL GME+ G
Sbjct 117 GGAGPEFTHGALSRVVELMLDGVPVVAMHRGTTWATHDGLRIDTGTYLPGMEEVAGTNVV 176
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
++GKP+ FL A D +G P +M+GDDL DVLAAQ VG+TGVLVRTGKFRQ LD
Sbjct 177 SVGKPSLAAFLTATDLMGTGPDVTMMVGDDLTGDVLAAQRVGLTGVLVRTGKFRQSILD- 235
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+A RP HV+DSVA LP LL
Sbjct 236 ----LAAQRPDHVVDSVAQLPKLL 255
>gi|226305013|ref|YP_002764971.1| hypothetical protein RER_15240 [Rhodococcus erythropolis PR4]
gi|226184128|dbj|BAH32232.1| conserved hypothetical protein [Rhodococcus erythropolis PR4]
Length=261
Score = 275 bits (702), Expect = 8e-72, Method: Compositional matrix adjust.
Identities = 143/266 (54%), Positives = 179/266 (68%), Gaps = 15/266 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVL+ SW+ I GA E VR++ RG+AC +LTNTT+R+ IA+ L AGI V A
Sbjct 7 VLFDIDGVLLTSWQPIEGAGEAVREVRRRGLACGFLTNTTSRSSSLIAQGLCDAGIEVEA 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++TA LT EY+ YP AR +++N+GD++ DL GI+ +D P+VV+L
Sbjct 67 SQIVTAARLTGEYVRATYPDARAWVLNHGDVSADLEGIEF--------DDAD--PEVVIL 116
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV +L GVPVVAMHR M W T DGLRIDTG YL G E+ G
Sbjct 117 GGAGPEFTHEALSRVLELLLAGVPVVAMHRGMMWETVDGLRIDTGTYLPGFEEVAGVNIA 176
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKP+ GFL A + + V+P+ VM+GDDL DVL++Q VG+TGVLVRTGKFRQ LD
Sbjct 177 AVGKPSLTGFLTATELMHVEPEATVMVGDDLIGDVLSSQRVGLTGVLVRTGKFRQTVLD- 235
Query 251 WLAGASATRPHHVIDSVAGLPPLLGC 276
S +P HVIDSVA LP LLG
Sbjct 236 ----LSVQKPDHVIDSVADLPALLGV 257
>gi|229490168|ref|ZP_04384015.1| transcriptional regulator, Fis family [Rhodococcus erythropolis
SK121]
gi|229322916|gb|EEN88690.1| transcriptional regulator, Fis family [Rhodococcus erythropolis
SK121]
Length=261
Score = 274 bits (701), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 143/266 (54%), Positives = 179/266 (68%), Gaps = 15/266 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVL+ SW+ I GA E VR++ RG+AC +LTNTT+R+ IA+ L AGI V A
Sbjct 7 VLFDIDGVLLTSWQPIEGAGEAVREVRRRGLACGFLTNTTSRSSTLIAQGLCDAGIEVEA 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++TA LT EY+ YP AR +++N+GD++ DL GI+ +D P+VV+L
Sbjct 67 SQIVTAARLTGEYVRATYPDARAWVLNHGDVSADLEGIEF--------DDAD--PEVVIL 116
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV +L GVPVVAMHR M W T DGLRIDTG YL G E+ G
Sbjct 117 GGAGPEFTHEALSRVLELLLAGVPVVAMHRGMMWETVDGLRIDTGTYLPGFEEVAGVNIA 176
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
A+GKP+ GFL A + + V+P+ VM+GDDL DVL++Q VG+TGVLVRTGKFRQ LD
Sbjct 177 AVGKPSLTGFLTATELMHVEPEATVMVGDDLIGDVLSSQRVGLTGVLVRTGKFRQTVLD- 235
Query 251 WLAGASATRPHHVIDSVAGLPPLLGC 276
S +P HVIDSVA LP LLG
Sbjct 236 ----LSVQKPDHVIDSVADLPALLGV 257
>gi|262200688|ref|YP_003271896.1| HAD-superfamily hydrolase [Gordonia bronchialis DSM 43247]
gi|262084035|gb|ACY20003.1| HAD-superfamily hydrolase, subfamily IIA [Gordonia bronchialis
DSM 43247]
Length=264
Score = 271 bits (694), Expect = 6e-71, Method: Compositional matrix adjust.
Identities = 136/268 (51%), Positives = 181/268 (68%), Gaps = 8/268 (2%)
Query 7 MAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGI 66
MA VL DIDGV+V SW+A+PGA + + +L R + +LTNTT+R+R +IA+ LG G
Sbjct 1 MALGVLLDIDGVMVTSWKALPGAVDALAELADRAVPRMFLTNTTSRSRGEIAQLLGDCGF 60
Query 67 PVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPD 126
V A +++TA LTAEY+ +P R +++N G I ED+ G+++ D P +
Sbjct 61 DVDASEILTAAALTAEYVSSTFPDKRVWVLNQGPIAEDMVGVELT--------DDPSSAQ 112
Query 127 VVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACG 186
V+VLG AGP F H LS+V MLDGVP +AMHR+MTW+T DGL+IDTG+YL G+E+A G
Sbjct 113 VIVLGGAGPVFTHDALSKVLELMLDGVPAIAMHRSMTWSTADGLKIDTGVYLEGLEKAVG 172
Query 187 KTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ 246
+ AIGKP+ GF AA D + ++P Q+VM+GDD+HNDVL AQA + GVLVRTGKFR++
Sbjct 173 RKIKAIGKPSPLGFRAAVDLMQMEPTQVVMVGDDMHNDVLGAQASALIGVLVRTGKFREE 232
Query 247 TLDRWLAGASATRPHHVIDSVAGLPPLL 274
L P HVIDSVA LP LL
Sbjct 233 ALRALQRDEFGPVPDHVIDSVADLPTLL 260
>gi|325673979|ref|ZP_08153669.1| inorganic pyrophosphatase [Rhodococcus equi ATCC 33707]
gi|325555244|gb|EGD24916.1| inorganic pyrophosphatase [Rhodococcus equi ATCC 33707]
Length=280
Score = 268 bits (684), Expect = 8e-70, Method: Compositional matrix adjust.
Identities = 141/264 (54%), Positives = 176/264 (67%), Gaps = 15/264 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ +PGA E + ++ RG A+LTNTT+RT +IA ALGAAG V
Sbjct 28 VLFDIDGVLVTSWKPVPGAVEALAEVRRRGGVRAFLTNTTSRTCDEIAAALGAAGFDVRP 87
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++++TA LT EYL YPG L+N+GDI D+P ++ +D P VVV+
Sbjct 88 EEIVTAARLTTEYLRSTYPGEPVLLLNHGDIRADMPDVEF--------DDV--DPRVVVI 137
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV M+ GVPVVAMHR + W+ +DGLR+DTG YL G+E A G
Sbjct 138 GGAGPEFTHEALSRVLDLMVSGVPVVAMHRALMWSESDGLRLDTGAYLPGLEDASGSRIV 197
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
++GKP+ GFL AA+ +G DP VM+GDD +DVL AQ VGMTGVLVRTGKFRQ LD
Sbjct 198 SVGKPSLAGFLTAAELMGADPASTVMVGDDFRSDVLPAQRVGMTGVLVRTGKFRQPVLD- 256
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+ RP H+IDSVA LP LL
Sbjct 257 ----LAVDRPDHIIDSVADLPALL 276
>gi|312141192|ref|YP_004008528.1| haloacid dehalogenase-like hydrolase [Rhodococcus equi 103S]
gi|311890531|emb|CBH49849.1| putative haloacid dehalogenase-like hydrolase [Rhodococcus equi
103S]
Length=280
Score = 267 bits (682), Expect = 1e-69, Method: Compositional matrix adjust.
Identities = 140/264 (54%), Positives = 176/264 (67%), Gaps = 15/264 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ +PGA E + ++ RG A+LTNTT+RT +IA ALGAAG V
Sbjct 28 VLFDIDGVLVTSWKPVPGAVEALAEVRRRGGVRAFLTNTTSRTCDEIAAALGAAGFDVRP 87
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++++TA LT EYL YPG L+N+GDI D+P ++ +D P VVV+
Sbjct 88 EEIVTAARLTTEYLRSTYPGEPVLLLNHGDIRADMPDVEF--------DDV--DPRVVVI 137
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV M+ GVPVVAMHR + W+ +DGLR+DTG YL G+E A G
Sbjct 138 GGAGPEFTHEALSRVLDLMVSGVPVVAMHRALMWSESDGLRLDTGAYLPGLEDASGSRIV 197
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
++GKP+ GFL AA+ +G DP VM+GDD +DVL AQ VGMTGVLVRTGKFRQ LD
Sbjct 198 SVGKPSLAGFLTAAELMGADPASTVMVGDDFRSDVLPAQRVGMTGVLVRTGKFRQPVLD- 256
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+ RP H++DSVA LP LL
Sbjct 257 ----LAVDRPDHILDSVADLPALL 276
>gi|15321582|gb|AAK95491.1|AF233387_3 unknown [Rhodococcus equi]
Length=259
Score = 267 bits (682), Expect = 1e-69, Method: Compositional matrix adjust.
Identities = 140/264 (54%), Positives = 176/264 (67%), Gaps = 15/264 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW+ +PGA E + ++ RG A+LTNTT+RT +IA ALGAAG V
Sbjct 7 VLFDIDGVLVTSWKPVPGAVEALAEVRRRGGVRAFLTNTTSRTCDEIAAALGAAGFDVRP 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++++TA LT EYL YPG L+N+GDI D+P ++ +D P VVV+
Sbjct 67 EEIVTAARLTTEYLRSTYPGEPVLLLNHGDIRADMPDVEF--------DDV--DPRVVVI 116
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP+F H LSRV M+ GVPVVAMHR + W+ +DGLR+DTG YL G+E A G
Sbjct 117 GGAGPEFTHEALSRVLDLMVSGVPVVAMHRALMWSESDGLRLDTGAYLPGLEDASGSRIV 176
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
++GKP+ GFL AA+ +G DP VM+GDD +DVL AQ VGMTGVLVRTGKFRQ LD
Sbjct 177 SVGKPSLAGFLTAAELMGADPASTVMVGDDFRSDVLPAQRVGMTGVLVRTGKFRQPVLD- 235
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+ RP H++DSVA LP LL
Sbjct 236 ----LAVDRPDHILDSVADLPALL 255
>gi|289757323|ref|ZP_06516701.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis
T85]
gi|289712887|gb|EFD76899.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis
T85]
gi|326902848|gb|EGE49781.1| LOW QUALITY PROTEIN: hydrolase [Mycobacterium tuberculosis W-148]
Length=277
Score = 265 bits (676), Expect = 8e-69, Method: Compositional matrix adjust.
Identities = 133/135 (99%), Positives = 134/135 (99%), Gaps = 0/135 (0%)
Query 1 VDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
+DVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA
Sbjct 1 MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEA 60
Query 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED
Sbjct 61 LGAAGIPVAADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPED 120
Query 121 CPEAPDVVVLGSAGP 135
CPEAPDVVVLGSA P
Sbjct 121 CPEAPDVVVLGSARP 135
>gi|312200039|ref|YP_004020100.1| HAD-superfamily hydrolase, subfamily IIA [Frankia sp. EuI1c]
gi|311231375|gb|ADP84230.1| HAD-superfamily hydrolase, subfamily IIA [Frankia sp. EuI1c]
Length=263
Score = 249 bits (637), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 137/267 (52%), Positives = 175/267 (66%), Gaps = 13/267 (4%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AV DIDGVL +SWRA+PGAA+ VRQL G+A A+LTNTT+RT+ I AL +AGI
Sbjct 5 AVFLDIDGVLTISWRALPGAAQAVRQLRDAGLAVAFLTNTTSRTKAAIGAALRSAGIEAR 64
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
D++ITA + A YL +PGAR L+N+GDIT DLP + P+ E PDVVV
Sbjct 65 DDEIITAATIGAAYLRRHHPGARVRLLNSGDITADLPDVRWA-----APD---EQPDVVV 116
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
LG AGP++ H L++V +L G +VA+ RN W T++G+ +DTG YL G+EQA G A
Sbjct 117 LGGAGPEYSHAALTQVLRDVLAGATLVALARNFYWATSEGMALDTGAYLAGLEQAAGTRA 176
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
+GKPA F AA D VGV + +M+GDDL +DVL AQA+G+TGVLVRTGKFR L
Sbjct 177 EVVGKPAPAFFSAALDLVGVTAGEALMVGDDLTSDVLGAQAIGLTGVLVRTGKFRADALT 236
Query 250 RWLAGASATRPHHVIDSVAGLPPLLGC 276
A+ P HV+DS+A LP LL
Sbjct 237 -----AAGGTPDHVVDSIADLPALLAA 258
>gi|294994782|ref|ZP_06800473.1| hypothetical protein Mtub2_09787 [Mycobacterium tuberculosis
210]
Length=325
Score = 248 bits (634), Expect = 5e-64, Method: Compositional matrix adjust.
Identities = 123/125 (99%), Positives = 124/125 (99%), Gaps = 0/125 (0%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+LFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA
Sbjct 1 MLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 60
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL
Sbjct 61 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 120
Query 131 GSAGP 135
GSA P
Sbjct 121 GSARP 125
>gi|29828745|ref|NP_823379.1| hydrolase [Streptomyces avermitilis MA-4680]
gi|29605849|dbj|BAC69914.1| putative hydrolase [Streptomyces avermitilis MA-4680]
Length=279
Score = 246 bits (627), Expect = 4e-63, Method: Compositional matrix adjust.
Identities = 131/265 (50%), Positives = 175/265 (67%), Gaps = 12/265 (4%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVL DIDGVL +SW+ +PGA E + ++ + LTNTT+RTR IA LGA+G PV+
Sbjct 21 AVLIDIDGVLTVSWKPLPGAIEALHRIRDASLGVVLLTNTTSRTRASIAATLGASGFPVS 80
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
A+D++TA TA +L PGARC L+N+GDI EDL G+ ++ +D PDVV+
Sbjct 81 AEDILTAPTATAAHLTDHCPGARCSLLNSGDIREDLVGVTLL-------DDTDTVPDVVI 133
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
+G AGP+FD+ L+RV+G + G +VAMHRN+ W T GL +D+G +L G+E A G A
Sbjct 134 VGGAGPEFDYAALNRVFGHLQRGARLVAMHRNLYWRTDRGLDLDSGAFLLGLEHAAGTRA 193
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
GKPA F AA R+G P Q VM+GDD+ +DVLAAQ G+TGVLV+TGK+ +T
Sbjct 194 EITGKPAPAFFEAALTRLGAGPGQAVMVGDDIESDVLAAQRTGITGVLVKTGKYLPET-- 251
Query 250 RWLAGASATRPHHVIDSVAGLPPLL 274
A++ RP HV+DSVA LP LL
Sbjct 252 ---HHAASARPDHVLDSVADLPALL 273
>gi|333918245|ref|YP_004491826.1| putative hydrolase [Amycolicicoccus subflavus DQS3-9A1]
gi|333480466|gb|AEF39026.1| Possible hydrolase [Amycolicicoccus subflavus DQS3-9A1]
Length=260
Score = 244 bits (622), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 128/266 (49%), Positives = 172/266 (65%), Gaps = 15/266 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFDIDGVLV SW I AA+ VR + G A +LT+TT+ T+ IA L GIPV
Sbjct 6 VLFDIDGVLVTSWEPIARAADAVRTVVEAGYASGFLTSTTSLTQADIAMRLWQCGIPVEP 65
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++++TA LTAE++ + GARC+L+N+G++ D+ I E E+PD+++L
Sbjct 66 EEIVTAAKLTAEFVKRHHEGARCWLLNSGEVQADMSDI----------EFAEESPDLIIL 115
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AGP F H LSRV M++GVPV+AMHR ++W T+ GL+ID G YL G+E + T
Sbjct 116 GGAGPVFTHEALSRVAELMVEGVPVIAMHRALSWTTSAGLKIDVGAYLPGLEAVGHRDIT 175
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+ F AA +GV P+++VM+GDD++ DVLA QA GMTGVLVRTGKFR +T++
Sbjct 176 VIGKPSERAFSTAAAMMGVGPREVVMVGDDVNADVLAGQAAGMTGVLVRTGKFRPETME- 234
Query 251 WLAGASATRPHHVIDSVAGLPPLLGC 276
P H+IDSVA LP LL
Sbjct 235 ----GLDEEPDHIIDSVADLPELLSS 256
>gi|302555585|ref|ZP_07307927.1| hydrolase [Streptomyces viridochromogenes DSM 40736]
gi|302473203|gb|EFL36296.1| hydrolase [Streptomyces viridochromogenes DSM 40736]
Length=266
Score = 243 bits (620), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 137/265 (52%), Positives = 177/265 (67%), Gaps = 10/265 (3%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVL DIDGVL +SWR +PGA E +R++ G+A +TNTT+RTR IA LG AG PV+
Sbjct 6 AVLVDIDGVLTVSWRPLPGAVEALREVREAGLAVLLVTNTTSRTRASIAATLGDAGFPVS 65
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
A+D++TA TA YL PGARC L+N+GDI EDL G+ VV + + G PDVV+
Sbjct 66 AEDILTAPAATAAYLAEHCPGARCALLNSGDIAEDLEGVTVVDAADSGA-----VPDVVL 120
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
+G AGP+F +R L R +G + G +VAMHRN+ W T +GLR+D+G +LTG+EQA A
Sbjct 121 VGGAGPEFGYRALDRAFGHLQRGARLVAMHRNLYWRTAEGLRLDSGAFLTGLEQAARVEA 180
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
GKPA F AA R+G ++ VM+GDD+ +DVLAAQ G+TGVLVRTGKF+ + L
Sbjct 181 EVTGKPARAFFEAALARLGASAEEAVMVGDDVESDVLAAQRAGVTGVLVRTGKFQPEALR 240
Query 250 RWLAGASATRPHHVIDSVAGLPPLL 274
A+ P HVIDS A LP LL
Sbjct 241 -----AADGTPDHVIDSFADLPGLL 260
>gi|297203917|ref|ZP_06921314.1| hydrolase [Streptomyces sviceus ATCC 29083]
gi|197713108|gb|EDY57142.1| hydrolase [Streptomyces sviceus ATCC 29083]
Length=264
Score = 230 bits (586), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 130/267 (49%), Positives = 169/267 (64%), Gaps = 12/267 (4%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVL DIDGVL +SW +P A +R++ G A +TNTT+RTR IA L AG PV
Sbjct 6 AVLIDIDGVLTVSWAPLPRAVAALREVREAGFGVALVTNTTSRTRASIAAVLEGAGFPVR 65
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
A+D++TA +TA YL PGARC L+N+GDI EDL G+ T +G E E DVVV
Sbjct 66 AEDILTAPAVTASYLADHCPGARCTLLNSGDIAEDLAGV-----TLVGGE--AEDVDVVV 118
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
LG AGP+F + L+ +G + G +VAMHRN+ W T DGL++D G +L G+E+A A
Sbjct 119 LGGAGPEFGYTALNHAFGHLQRGARLVAMHRNLYWRTEDGLQLDAGAFLAGLERAARTEA 178
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
GKP+ F AA R+GV + +M+GDD+ +DVLAAQ G+TGVLV+TGK+ +T
Sbjct 179 EVTGKPSPAFFEAALARLGVGADEALMVGDDIESDVLAAQRAGLTGVLVKTGKYLPETHR 238
Query 250 RWLAGASATRPHHVIDSVAGLPPLLGC 276
AS T P HVI+S A LP LLG
Sbjct 239 ----SASGT-PDHVIESFADLPALLGA 260
>gi|111221102|ref|YP_711896.1| putative hydrolase [Frankia alni ACN14a]
gi|111148634|emb|CAJ60308.1| Putative hydrolase [Frankia alni ACN14a]
Length=261
Score = 229 bits (584), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 130/265 (50%), Positives = 170/265 (65%), Gaps = 15/265 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL DIDGVL +SW+A+PGA + + +L G+ A++TNTT+R R IA AL AAG V
Sbjct 7 VLIDIDGVLTVSWQALPGAPQALERLRAAGLGVAFVTNTTSRDRASIAAALVAAGFTVDP 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCP-EAPDVVV 129
+V TA + A YL +P ARC ++N+GDI DL G+ P E PDV+V
Sbjct 67 GEVFTAPAMAASYLRQHHPAARCHVLNSGDIRADLDGVAF---------SAPGERPDVIV 117
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
LG AGP+F + +++V+ W DGVP+VA+HRN+ W T GL++DTG YL G+EQA + A
Sbjct 118 LGGAGPEFSYEAVNQVFAWATDGVPLVALHRNLFWRTDGGLQLDTGAYLHGLEQALDRPA 177
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
+GKPAAE F A + + VMIGDD+ +DVLAA G+TGVLVRTGKFR +L
Sbjct 178 VVVGKPAAEFFATALRALDSRAEAAVMIGDDVEHDVLAAARHGLTGVLVRTGKFRPDSL- 236
Query 250 RWLAGASATRPHHVIDSVAGLPPLL 274
A++ RP HVIDS A LP LL
Sbjct 237 ----AAASGRPDHVIDSFADLPALL 257
>gi|320010759|gb|ADW05609.1| HAD-superfamily hydrolase, subfamily IIA [Streptomyces flavogriseus
ATCC 33331]
Length=266
Score = 223 bits (567), Expect = 3e-56, Method: Compositional matrix adjust.
Identities = 127/268 (48%), Positives = 165/268 (62%), Gaps = 11/268 (4%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVL DIDGVL +SW +PGA E + L + A +TNTT+RTR IA L +G PV
Sbjct 6 AVLIDIDGVLTVSWEPLPGAVEAMEALRAAEVPLALVTNTTSRTRAAIARRLADSGFPVG 65
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEA-PDVV 128
DD++TA +TA +L +PGARC L+N GD+ DL G+ +V ED A PDVV
Sbjct 66 PDDILTAPAVTAAHLRERHPGARCLLINTGDVRGDLSGVPLVEE-----EDGEGAVPDVV 120
Query 129 VLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
VLG AG F + L+R + + G +VAMHRN+ W T DGL +D+G +L G+E A
Sbjct 121 VLGGAGAAFTYAALNRAFHLVQQGAVLVAMHRNLYWRTADGLDLDSGAFLLGLEHAARTE 180
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A GKP+ F AA +G DP +M+M+GDD+ DVLAAQ G+TGVLVRTGK+R +T
Sbjct 181 AVVTGKPSGAFFAAALAHLGADPARMLMVGDDIETDVLAAQHHGITGVLVRTGKYRPET- 239
Query 249 DRWLAGASATRPHHVIDSVAGLPPLLGC 276
A+ P HV+DS A +P LLG
Sbjct 240 ----HAAAEGAPDHVVDSFADVPALLGL 263
>gi|134102052|ref|YP_001107713.1| HAD superfamily hydrolase [Saccharopolyspora erythraea NRRL 2338]
gi|291004913|ref|ZP_06562886.1| HAD superfamily hydrolase [Saccharopolyspora erythraea NRRL 2338]
gi|133914675|emb|CAM04788.1| hydrolase, haloacid dehalogenase-like family [Saccharopolyspora
erythraea NRRL 2338]
Length=257
Score = 218 bits (556), Expect = 5e-55, Method: Compositional matrix adjust.
Identities = 119/267 (45%), Positives = 169/267 (64%), Gaps = 15/267 (5%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
A+L DIDGVL +SW+ +PG E + +L G +TNTT+RTR I AL G +A
Sbjct 6 ALLIDIDGVLTVSWQPLPGNVEALARLRAAGFGVRLVTNTTSRTRSSIVRALRTGGFDIA 65
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
DDV+T V TAEYL +PGARC L+N+GD+T+DL G+ +V VVV
Sbjct 66 TDDVMTGVVATAEYLRRHHPGARCLLLNSGDVTDDLEGVTLVDDDPD----------VVV 115
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
LG AGP+F + ++RV+ + G VAMH ++ W T++GL +D+G +L G+E+A + A
Sbjct 116 LGGAGPEFSYGAINRVFRHVQRGAAFVAMHNSLRWRTSEGLALDSGAFLLGIERAANREA 175
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
+GKP+AE F +A +GV+ +M+GDD+ +DVLAAQ +G+TGVLVRTGK+ T +
Sbjct 176 VVVGKPSAEFFTSALRSLGVESGAALMVGDDVESDVLAAQRLGITGVLVRTGKYTAATTE 235
Query 250 RWLAGASATRPHHVIDSVAGLPPLLGC 276
A++ P HV+DS A +P LLG
Sbjct 236 -----AASGVPDHVLDSFADVPSLLGI 257
>gi|221635864|ref|YP_002523740.1| HAD-superfamily subfamily IIA hydrolase [Thermomicrobium roseum
DSM 5159]
gi|221157963|gb|ACM07081.1| HAD-superfamily subfamily IIA hydrolase [Thermomicrobium roseum
DSM 5159]
Length=258
Score = 209 bits (532), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 113/266 (43%), Positives = 161/266 (61%), Gaps = 16/266 (6%)
Query 9 AAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPV 68
+ L D+DGVL + IPGA + V +L RGI LTNTT RTRRQ+ L G PV
Sbjct 5 SGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLRELGFPV 64
Query 69 AADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVV 128
A D+++TAG TA YL YPG C+L+ +GD+ E+ GI +V ED ++ VV
Sbjct 65 ADDEIVTAGAATAAYLRAHYPGEPCYLLVDGDVQEEFAGIPLV-------ED--DSATVV 115
Query 129 VLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
V G AGP + + L+R + +L G VAMHRN+ W+ DG +DTG +L G+E A G+
Sbjct 116 VFGGAGPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALDTGAFLLGLEAALGRQ 175
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A +GKP+ + F A +R+G+ P+++ ++GD L D+L A+ +GMTGVLV+TG+FR L
Sbjct 176 AHLVGKPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDL 235
Query 249 DRWLAGASATRPHHVIDSVAGLPPLL 274
+ RP ++ S+A LP L
Sbjct 236 E-------LGRPDALLPSIAELPSWL 254
>gi|116753965|ref|YP_843083.1| HAD family hydrolase [Methanosaeta thermophila PT]
gi|116665416|gb|ABK14443.1| HAD-superfamily subfamily IIA hydrolase like protein [Methanosaeta
thermophila PT]
Length=257
Score = 168 bits (426), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 90/262 (35%), Positives = 144/262 (55%), Gaps = 14/262 (5%)
Query 9 AAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPV 68
+A L D+DGVL + +PGA E + + +G + +++N+T R R +A+ L G +
Sbjct 6 SAFLMDLDGVLYVGRNPVPGARECLELMEEKGYSFRFISNSTRRCRASVAKRLSEMGYRI 65
Query 69 AADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVV 128
+ + T V E +H + RC+L++ GD+ D + L + D V
Sbjct 66 QPERIFTPSVAAIERIHRS-GKRRCYLISTGDVHRDFEDAGIAL--------VEDEADFV 116
Query 129 VLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
V+G AG F + L+R + +L+G ++A+ + W ++GL + G ++ +E A GK
Sbjct 117 VIGDAGSNFTYERLNRAFNHVLEGADMIALEMDRYWRESEGLVLSAGPFVAALEYATGKR 176
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A +GKP+ E F A + +GV+PQ MIGDD+ DV AQ VGM G+LVRTGK+R + +
Sbjct 177 AELVGKPSPEFFSLALNDMGVNPQDAAMIGDDIITDVGGAQRVGMLGILVRTGKYRPEHV 236
Query 249 DRWLAGASATRPHHVIDSVAGL 270
+R S RP V+DS+A L
Sbjct 237 ER-----SGVRPDCVLDSIADL 253
>gi|91775199|ref|YP_544955.1| HAD family hydrolase [Methylobacillus flagellatus KT]
gi|91775343|ref|YP_545099.1| HAD family hydrolase [Methylobacillus flagellatus KT]
gi|91709186|gb|ABE49114.1| HAD-superfamily subfamily IIA hydrolase, hypothetical 2 [Methylobacillus
flagellatus KT]
gi|91709330|gb|ABE49258.1| HAD-superfamily subfamily IIA hydrolase, hypothetical 2 [Methylobacillus
flagellatus KT]
gi|167042418|gb|ABZ07144.1| putative haloacid dehalogenase-like hydrolase [uncultured marine
microorganism HF4000_ANIW133B20]
Length=260
Score = 166 bits (420), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 96/267 (36%), Positives = 151/267 (57%), Gaps = 18/267 (6%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVLFD+DGVL + IPGA ET+ L +G+ C ++TNT+T +R + + + G +A
Sbjct 8 AVLFDLDGVLHIGNSPIPGAIETIDLLRRQGLGCRFVTNTSTLSRHSLHQKILGMGFYIA 67
Query 70 ADDVITAGVLTAEYLHG-AYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVV 128
+++I+A +YL P R L + D+ +D + + +
Sbjct 68 PEEIISAPEAALKYLEQLGNPICRFLLAD--DVKKDFSHF----------RQSNTSAEYI 115
Query 129 VLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
V+G G + + ++ V+ + +G ++A+H+N W T GL+ID G ++TG+E A G
Sbjct 116 VVGDIGQAWTYDIMNEVFNCLKNGAKLIAIHKNRFWQTEAGLQIDIGGFITGLEYAAGTQ 175
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A IGKPA E F A + + +++MIGDD+ +D+ AQ G+ GVLVRTGKFR++
Sbjct 176 AMIIGKPATEFFQIALADLKLPASEVLMIGDDVDSDIGGAQKAGIRGVLVRTGKFREE-- 233
Query 249 DRWLAGASATRPHHVIDSVAGLPPLLG 275
+LA +S T P +IDS+A LP LLG
Sbjct 234 --YLASSSVT-PDLIIDSIADLPALLG 257
>gi|253996501|ref|YP_003048565.1| HAD-superfamily subfamily IIA hydrolase-like protein [Methylotenera
mobilis JLW8]
gi|253983180|gb|ACT48038.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylotenera
mobilis JLW8]
Length=258
Score = 162 bits (409), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 96/268 (36%), Positives = 145/268 (55%), Gaps = 22/268 (8%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+LFD+DGVL AI GA + V + G+ C ++TNT+T + + L G + +
Sbjct 9 ILFDLDGVLYTGSSAISGAIDAVNTIRASGMPCRFVTNTSTLSLASLHHKLTTLGFSIPS 68
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEA---PDV 127
++I+A T YL A C L+ D+ +D + P+A PD
Sbjct 69 TEIISAPQATLLYLK-QQAHATCRLLLADDVKKDFDAL-------------PQAATNPDY 114
Query 128 VVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGK 187
+V+G G + + L+ V+ ++ G ++ +H+N W T GL++D G ++ +E A G
Sbjct 115 IVIGDIGNAWTYTLLNDVFNALMQGAKLITIHKNKFWQTEHGLQMDIGGFVDALEYASGV 174
Query 188 TATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQT 247
A IGKPA + F A D +G+ P + +M+GDD+ DV Q VG+TGVLV+TGK+RQ
Sbjct 175 KAMVIGKPAPDFFKIALDDLGLTPAEAMMVGDDIDVDVGGGQQVGLTGVLVKTGKYRQHY 234
Query 248 LDRWLAGASATRPHHVIDSVAGLPPLLG 275
D ASA +P VIDSVA LP +LG
Sbjct 235 AD-----ASAIKPDIVIDSVADLPKILG 257
>gi|24217163|ref|NP_714646.1| phospholysine phosphohistidine inorganic pyrophosphate phosphatase
[Leptospira interrogans serovar Lai str. 56601]
gi|24202203|gb|AAN51661.1| haloacid dehalogenase-like protein [Leptospira interrogans serovar
Lai str. 56601]
Length=269
Score = 161 bits (407), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 86/260 (34%), Positives = 144/260 (56%), Gaps = 16/260 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL D+DGVL A+PGA+E + L I +LTNTTT++R++++E L GIP
Sbjct 19 VLLDLDGVLYTGNTALPGASEAISYLKKNHIPYLFLTNTTTKSRKELSEFLNDLGIPAEE 78
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+ ++ + EY+ + F V +I +DL I++ +T P+ V++
Sbjct 79 EKILNSPRAAGEYIRET-GNPKTFFVIKKEIQDDLKEINLESNT----------PEAVLV 127
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G +++++ L+ ++ + +G ++A+H+ W T +GL +D G +++G+E A G A
Sbjct 128 GDIGKEWNYQILNEIFQKVKNGARLIALHKGKFWQTKEGLMLDIGAFVSGIEYATGIKAE 187
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+ F AA + + +MIGDDL +DV AQA G+ GVLV+TGK+R L
Sbjct 188 IIGKPSGAFFNAALKMISAEASHTIMIGDDLDSDVGGAQAYGIRGVLVKTGKYRDGILKN 247
Query 251 WLAGASATRPHHVIDSVAGL 270
S P+ V D+++ +
Sbjct 248 -----SNIHPYAVWDNISSI 262
>gi|45655662|ref|YP_003471.1| haloacid dehalogenase-like protein [Leptospira interrogans serovar
Copenhageni str. Fiocruz L1-130]
gi|45602633|gb|AAS72108.1| haloacid dehalogenase-like protein [Leptospira interrogans serovar
Copenhageni str. Fiocruz L1-130]
Length=269
Score = 159 bits (402), Expect = 4e-37, Method: Compositional matrix adjust.
Identities = 85/260 (33%), Positives = 144/260 (56%), Gaps = 16/260 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL D+DGVL A+PGA+E + L I +LTNTTT++R++++E L GIP
Sbjct 19 VLLDLDGVLYTGNTALPGASEAISYLKKNHIPYLFLTNTTTKSRKELSEFLNDLGIPAEE 78
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+ ++ + EY+ + F V +I +DL I++ +T P+ V++
Sbjct 79 EKILNSPRAAGEYIRET-GNPKTFFVIKKEIQDDLKEINLESNT----------PEAVLV 127
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G +++++ L+ ++ + +G ++A+H+ W T +GL +D G +++G+E A G A
Sbjct 128 GDIGKEWNYQILNEIFQKVKNGARLIALHKGKFWQTKEGLMLDIGAFVSGIEYATGIKAE 187
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+ F AA + + +MIGDDL +DV AQA G+ GVLV+TGK+R L
Sbjct 188 IIGKPSGAFFNAALKMISAEASHTIMIGDDLDSDVGGAQACGIRGVLVKTGKYRDGILKN 247
Query 251 WLAGASATRPHHVIDSVAGL 270
S P+ V ++++ +
Sbjct 248 -----SNIHPYAVWNNISSI 262
>gi|334109499|ref|ZP_08483778.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylomicrobium
album BG8]
gi|333600131|gb|EGL04948.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylomicrobium
album BG8]
Length=260
Score = 158 bits (400), Expect = 7e-37, Method: Compositional matrix adjust.
Identities = 87/264 (33%), Positives = 144/264 (55%), Gaps = 16/264 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+L D+DGVL + R + GA E VR++ RG C ++TNT+T +R + + L G +
Sbjct 10 ILIDLDGVLYVGSRTVDGAIEAVREIKRRGYCCRFVTNTSTLSRASLHKKLAGFGFDIDE 69
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++++A +L + C L+ D+ +D + D V++
Sbjct 70 HEIVSAPQAALIHLR-QFGDPVCHLLLTDDVKQDFRHL----------RQSDSKADFVIV 118
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G + + L+ V+ ++ G ++A+H+N W T GL++D G +++G+E A K AT
Sbjct 119 GDIGNAWSYPLLNNVFNLLIGGAELIAIHKNRFWQTERGLQLDIGAFVSGLEYASRKQAT 178
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+++ F AA + +G+ P+Q+ ++GDD+ DV Q G+TG+LV+TGK+RQ
Sbjct 179 IIGKPSSDFFKAALNELGMPPEQVAIVGDDIDADVGGGQRAGLTGILVKTGKYRQD---- 234
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
A S P +I SVA LP LL
Sbjct 235 -YAENSQIVPGLIIPSVAKLPNLL 257
>gi|192360525|ref|YP_001983356.1| HAD-superfamily hydrolase [Cellvibrio japonicus Ueda107]
gi|190686690|gb|ACE84368.1| HAD-superfamily subfamily IIA hydrolase, TIGR01458 [Cellvibrio
japonicus Ueda107]
Length=262
Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 99/269 (37%), Positives = 141/269 (53%), Gaps = 19/269 (7%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+L D+DG L + IPGA E V L G +LTNTTT+++ Q+ L G +A
Sbjct 8 ILLDLDGTLYVGNDPIPGALEAVAHLRREGFVLRFLTNTTTKSQAQLIAQLRHLGFELAD 67
Query 71 DDVITAGV---LTAEYL-HGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPD 126
+++++A V L E L A R + + I D G APD
Sbjct 68 EELVSAPVAARLALETLQQAAGRPLRIWPLVAEAIKPDFSGFAW----------DEAAPD 117
Query 127 VVVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACG 186
VVLG G +D ++R++ M G ++A+H+N W T DGL+ D G ++ G+E
Sbjct 118 YVVLGDIGDAWDLALINRLFNAMHSGAELIALHKNRFWQTADGLKADIGFFVAGLEYVSS 177
Query 187 KTATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ 246
KTA +GKP + F D VGV Q +M+GDD+ +DV AQA+G+ G LV+TGKFRQ
Sbjct 178 KTALVMGKPNRDFFQGLLDSVGVSAGQALMVGDDIDSDVGGAQAMGIGGCLVKTGKFRQA 237
Query 247 TLDRWLAGASATRPHHVIDSVAGLPPLLG 275
D+ SA P ++DS+A LP LG
Sbjct 238 YFDQ-----SAVTPDILLDSIANLPEALG 261
>gi|297537265|ref|YP_003673034.1| HAD-superfamily subfamily IIA hydrolase-like protein [Methylotenera
versatilis 301]
gi|297256612|gb|ADI28457.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylotenera
versatilis 301]
Length=258
Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 89/265 (34%), Positives = 143/265 (54%), Gaps = 17/265 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+LFD+DGVL AI GA E + +L I C ++TNT+T + + + + G +
Sbjct 10 ILFDLDGVLYTGSNAIDGAVEAIEKLRASHI-CRFVTNTSTLSLVSLQQKINKLGFAIPI 68
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+++I+A T YL C L+ D+ +D A + +V+
Sbjct 69 NEIISAPQATLFYLQ-RQKNPVCRLLLAEDVKQDFKEF----------HQSVAAANYIVI 117
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G + + L++V+ ++ G ++A+H+N W T GL++D G ++ +E A G A
Sbjct 118 GDIGSTWSYTLLNQVFNDLMQGAKLIAIHKNKFWQTEHGLQMDIGGFVEALEYASGVKAM 177
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+A+ F A D +G+ ++ MIGDD+ DV +Q +G+TG+LV+TGK+RQ
Sbjct 178 IIGKPSADFFQIALDDMGLKSSEVAMIGDDIDVDVGGSQQIGLTGILVKTGKYRQN---- 233
Query 251 WLAGASATRPHHVIDSVAGLPPLLG 275
A AS +P +IDS+A LP LLG
Sbjct 234 -YAEASQVKPDLLIDSIADLPKLLG 257
>gi|114321702|ref|YP_743385.1| HAD family hydrolase [Alkalilimnicola ehrlichii MLHE-1]
gi|114228096|gb|ABI57895.1| HAD-superfamily subfamily IIA hydrolase like protein [Alkalilimnicola
ehrlichii MLHE-1]
Length=260
Score = 155 bits (392), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 88/236 (38%), Positives = 134/236 (57%), Gaps = 14/236 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
+L DI GVL A+PGA E +++L G+A + TNT+ TR +AE LG G VAA
Sbjct 9 LLLDIGGVLYQGAEALPGAPEAMQRLRASGLALRFATNTSRTTRAALAEKLGRLGFDVAA 68
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+++ TA + + + G R L+ + D+ DL G D P PD V++
Sbjct 69 EEIFTAPLAAVQTIRER--GLRPLLLVHPDLGPDLTGF----------PDGP--PDAVLI 114
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AG FD+R L+R + +++G P++A+ RN + DGL +D G ++ +E A G A
Sbjct 115 GDAGEHFDYRGLNRAFRLLMEGAPLLALARNRYFREQDGLSLDVGPFVAALEYASGVAAE 174
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ 246
GKPA F AA+ +GV P++++M+GDD+ +DV+ A G+ LVRTGKF +
Sbjct 175 VYGKPAPGFFREAAEALGVAPERLLMVGDDVESDVIGALDAGLQAALVRTGKFSPE 230
>gi|116332521|ref|YP_802238.1| sugar phosphatase [Leptospira borgpetersenii serovar Hardjo-bovis
JB197]
gi|116127388|gb|ABJ77480.1| Sugar phosphatase [Leptospira borgpetersenii serovar Hardjo-bovis
JB197]
Length=268
Score = 153 bits (386), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 88/264 (34%), Positives = 137/264 (52%), Gaps = 16/264 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL D+DGVL +PGA E + L I +LTNTTT++R+ I+E L IPV
Sbjct 18 VLLDLDGVLYTGDSVLPGAREAISYLKENHIPHLFLTNTTTKSRKGISEFLNDLKIPVEE 77
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
V+ + EY+ + F V ++ +DL GID EA V++
Sbjct 78 KRVLNSPRAAGEYIRET-GNPKTFFVIRKEVKKDLEGIDF-------ERKISEA---VLI 126
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G ++++ L+ ++ + G ++A+H+ W T +GL +D G +++G+E A G A
Sbjct 127 GDIGEEWNYGILNDIFQKVKGGARLIALHKGKYWQTKEGLMLDIGTFVSGIEYATGVKAE 186
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
IGKP+ F AA + + +MIGDDL +DV AQ G+ GVLV+TGK+R + L
Sbjct 187 VIGKPSPAFFKAALKMISTQASETIMIGDDLDSDVGGAQVCGIRGVLVKTGKYRNEILQN 246
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
S RP + ++++ L P
Sbjct 247 -----SNVRPDAIWENISSLIPFF 265
>gi|307353415|ref|YP_003894466.1| HAD-superfamily subfamily IIA hydrolase-like protein [Methanoplanus
petrolearius DSM 11571]
gi|307156648|gb|ADN36028.1| HAD-superfamily subfamily IIA hydrolase like protein [Methanoplanus
petrolearius DSM 11571]
Length=260
Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 86/265 (33%), Positives = 145/265 (55%), Gaps = 14/265 (5%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL DIDGVL IPGA++ + L I ++NTT ++++ I+E LG+ G +
Sbjct 7 VLLDIDGVLYTGDEPIPGASDAIGFLKDSKIPFRCISNTTRKSKKSISEKLGSYGFDIPV 66
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
+ + T + L CFL+ GD+ +D +L I E P+A V+V
Sbjct 67 EHIFTPASVVVSILKENNV-KNCFLLTWGDVRQD------ILKEGI-TESIPDAGAVIV- 117
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G AG FD+ ++++ + + +G A+ ++ W +DGL + G ++ G+E A G++A
Sbjct 118 GDAGDNFDYSSMNQAFRLINEGAEFYALEKDRYWMDSDGLSLSAGPFVLGLEYATGRSAI 177
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
+GKP+ F A + + V +M+GDD+++DV AQ +G+ G+LVRTGKF ++ L +
Sbjct 178 LVGKPSPSFFTKALESMNVTASGAIMVGDDINSDVGGAQNIGVRGMLVRTGKFSEERLKK 237
Query 251 WLAGASATRPHHVIDSVAGLPPLLG 275
S P+ +IDS+ LP ++G
Sbjct 238 -----SEIIPYRIIDSIGVLPEIIG 257
>gi|114776581|ref|ZP_01451626.1| haloacid dehalogenase-like protein [Mariprofundus ferrooxydans
PV-1]
gi|114553411|gb|EAU55809.1| haloacid dehalogenase-like protein [Mariprofundus ferrooxydans
PV-1]
Length=260
Score = 151 bits (381), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 91/266 (35%), Positives = 141/266 (54%), Gaps = 20/266 (7%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVLFD+DGVL + +PGAAE+V+ + G++ A +TNTTT RR IA+ L GIP+
Sbjct 11 AVLFDLDGVLYIGNALLPGAAESVQYIKDLGLSVAGVTNTTTSPRRAIAKKLADLGIPMD 70
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
D++ T L + + G T L D +L E E PD +V
Sbjct 71 PDNIYTPAALAVQAI--------------GTSTAQLYVQDALLEDFSTVELTKEKPDFIV 116
Query 130 LGSAGPQ-FDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
+G G + + L R++ ++DG ++A+H+N W DGL +D G ++T +E A G
Sbjct 117 MGDLGDRGYTPAILHRIFNQVMDGATLLALHKNRFWQKPDGLHLDIGPFVTAIEYATGTQ 176
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A +GKP+ F + V P+ +MIGDD+ +D+ AQ G+ LV+TGK+RQ +
Sbjct 177 AIVLGKPSQAFFHGVCIALHVHPEAALMIGDDIESDIAGAQQAGLHTALVQTGKYRQAFV 236
Query 249 DRWLAGASATRPHHVIDSVAGLPPLL 274
++ + R ++ S+A LP L
Sbjct 237 EQ-----TGIRADLILPSIASLPEAL 257
>gi|268317966|ref|YP_003291685.1| HAD-superfamily subfamily IIA hydrolase like protein [Rhodothermus
marinus DSM 4252]
gi|262335500|gb|ACY49297.1| HAD-superfamily subfamily IIA hydrolase like protein [Rhodothermus
marinus DSM 4252]
Length=257
Score = 150 bits (380), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 93/264 (36%), Positives = 133/264 (51%), Gaps = 19/264 (7%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
A +FD+DG L +A+PGA E +R L G A + TNTT+++RRQ+ E L G +
Sbjct 12 AFVFDLDGTLYQGEQALPGAVEAIRALQQAGYAVCFATNTTSKSRRQLVEKLRRLGFEAS 71
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
AD V + L +L GA +L+ ED G+ P++ PD VV
Sbjct 72 ADRVFSPPALAGAFLRAQ--GASAYLLVPEATLEDFAGVR--------PDET--HPDYVV 119
Query 130 LGSAGPQFDHRTLSRVYGWMLD-GVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKT 188
+G GP + L+R + + + G ++ + R W T GL++D G ++ +E A G+
Sbjct 120 VGDLGPAWTFERLNRAFRLIQEHGARLIGLGRTRYWQTDAGLQLDAGPFIAALEYATGRE 179
Query 189 ATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
A GKP F + P Q+ M+GDD+ DV AA G+ GVLVRTGKFR L
Sbjct 180 AIIFGKPDRRFFEQICAALAPPPGQVAMVGDDIRTDVEAAMQAGLRGVLVRTGKFRPSDL 239
Query 249 DRWLAGASATRPHHVIDSVAGLPP 272
+ RP V+DSVA L P
Sbjct 240 E------GPVRPEVVLDSVADLRP 257
>gi|253999927|ref|YP_003051990.1| HAD-superfamily subfamily IIA hydrolase-like protein [Methylovorus
glucosetrophus SIP3-4]
gi|253986606|gb|ACT51463.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylovorus
glucosetrophus SIP3-4]
Length=259
Score = 150 bits (379), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 90/266 (34%), Positives = 144/266 (55%), Gaps = 18/266 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFD+DGVL + + + GA + V ++ + G+ C ++TNT+T + + LG+ G V
Sbjct 10 VLFDLDGVLYIGGKPVEGAMDAVDRIRNAGLPCRFVTNTSTLSLASLQAKLGSLGFAVET 69
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGD-ITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
+++I+A AR +L+ GD + L DV+ + +A + +V
Sbjct 70 EEIISAT-----------QAARLYLMRQGDPVCRFLLAEDVMQDFADFRQSDTDA-EFIV 117
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
+G G + +R L+ V+ ++ G ++A+H+N W T GL++D G ++TG+E A G
Sbjct 118 IGDIGDAWSYRLLNEVFNCLMRGAKLIAIHKNRYWQTEHGLQMDIGAFITGLEYASGAQT 177
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
T +GKP+A+ F A + V V+IGDD+ D+ AQ G+ GVLV+TGK+RQ D
Sbjct 178 TLMGKPSADFFAMALISMSVAACDAVLIGDDIDADIGGAQQAGLHGVLVQTGKYRQAYCD 237
Query 250 RWLAGASATRPHHVIDSVAGLPPLLG 275
AS P VI S+ P LLG
Sbjct 238 -----ASTIHPDRVIPSIREFPDLLG 258
>gi|313201900|ref|YP_004040558.1| had-superfamily subfamily iia hydrolase-like protein [Methylovorus
sp. MP688]
gi|312441216|gb|ADQ85322.1| HAD-superfamily subfamily IIA hydrolase like protein [Methylovorus
sp. MP688]
Length=259
Score = 150 bits (378), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 90/266 (34%), Positives = 144/266 (55%), Gaps = 18/266 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFD+DGVL + + + GA + V ++ + G+ C ++TNT+T + + LG+ G V
Sbjct 10 VLFDLDGVLYIGGKPVEGAMDAVDRIRNAGLPCRFVTNTSTLSLASLQAKLGSLGFAVET 69
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGD-ITEDLPGIDVVLSTEIGPEDCPEAPDVVV 129
+++I+A AR +L+ GD + L DV+ + +A + +V
Sbjct 70 EEIISA-----------TQAARLYLMRQGDPVCRFLLAEDVMQDFADFRQSDTDA-EFIV 117
Query 130 LGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTA 189
+G G + +R L+ V+ ++ G ++A+H+N W T GL++D G ++TG+E A G
Sbjct 118 IGDIGDAWSYRLLNEVFNCLMRGAKLIAIHKNRYWQTEHGLQMDIGAFITGLEYASGAQT 177
Query 190 TAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLD 249
T +GKP+A+ F A + V V+IGDD+ D+ AQ G+ GVLV+TGK+RQ D
Sbjct 178 TLMGKPSADFFAMALISMSVAACDAVLIGDDIDADIGGAQQAGLHGVLVQTGKYRQAYCD 237
Query 250 RWLAGASATRPHHVIDSVAGLPPLLG 275
AS P VI S+ P LLG
Sbjct 238 -----ASTIHPDRVIPSIREFPDLLG 258
>gi|53804785|ref|YP_113604.1| HAD superfamily hydrolase [Methylococcus capsulatus str. Bath]
gi|53758546|gb|AAU92837.1| hydrolase, haloacid dehalogenase-like family [Methylococcus capsulatus
str. Bath]
Length=264
Score = 149 bits (377), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 89/264 (34%), Positives = 139/264 (53%), Gaps = 16/264 (6%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VLFD+DGVL + + IPGA E V ++ G C ++TNT+T + + + A G PV
Sbjct 11 VLFDLDGVLYVDSQPIPGAVEAVAKIKAGGWICRFVTNTSTSSLATLERKIRALGFPVER 70
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
++I+A A H G L+ D+ D GI P+ E + +VL
Sbjct 71 SEIISAP--QAALRHLRTTGLSAHLLLEDDVKADFAGI---------PQASMEDAEALVL 119
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G + H L R++ +L G ++A+H+N W T GLR+D G + +E G
Sbjct 120 GDIPEVWTHDCLDRMFNAILRGAQLIAVHKNRFWQTGQGLRMDIGGLVAALEYCAGVRPW 179
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTLDR 250
+GKP+A+ F A +G+ P+++ ++GDD+ D+ +A G+ G+LVRTGKFR L+
Sbjct 180 VMGKPSADFFAIALRDMGLPPERVAIVGDDIEADIGGGRAAGLYGILVRTGKFRPFQLE- 238
Query 251 WLAGASATRPHHVIDSVAGLPPLL 274
+ +P +IDS+A LP LL
Sbjct 239 ----TGSMQPDRIIDSIADLPDLL 258
>gi|345131096|gb|EGW61998.1| HAD-superfamily subfamily IIA hydrolase like protein [Dechlorosoma
suillum PS]
Length=266
Score = 147 bits (371), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 96/237 (41%), Positives = 136/237 (58%), Gaps = 19/237 (8%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
AVL D+ GVL + R +PGAA +++L G+ +LTNTT R+ + + L + G+ VA
Sbjct 19 AVLIDLAGVLHVGDRPVPGAAAALQRLRASGLPLRFLTNTTRSPRQALVQLLHSMGLAVA 78
Query 70 ADDVITAGVLTAEYLH--GAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDV 127
+++ TA TA+ + G +P +LV+ ++ E+GP PE PD
Sbjct 79 PEEIQTAVRATAQLVRQRGLHP---HYLVHPA------------IADEVGPSH-PE-PDA 121
Query 128 VVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGK 187
VVLG AG F L+R + + G P++AM RN + DGL +D G ++ +E G
Sbjct 122 VVLGDAGEHFTFDALNRAFRLLQAGCPLIAMARNRYFQEPDGLTLDLGAFVAALEYGAGV 181
Query 188 TATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFR 244
A +GKPAA FL A +GV P + V+IGDDL +D+ AQAVGM GVLVRTGKFR
Sbjct 182 RAEVVGKPAAPFFLGALAELGVVPGEAVLIGDDLRDDIGGAQAVGMPGVLVRTGKFR 238
>gi|116329636|ref|YP_799355.1| sugar phosphatase [Leptospira borgpetersenii serovar Hardjo-bovis
L550]
gi|116122529|gb|ABJ80422.1| Sugar phosphatase [Leptospira borgpetersenii serovar Hardjo-bovis
L550]
Length=258
Score = 147 bits (370), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 83/238 (35%), Positives = 127/238 (54%), Gaps = 11/238 (4%)
Query 11 VLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVAA 70
VL D+DGVL +PGA E + L I +LTNTTT++R+ I+E L IPV
Sbjct 18 VLLDLDGVLYTGDSVLPGAREAISYLKENHIPHLFLTNTTTKSRKGISEFLNDLKIPVEE 77
Query 71 DDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVL 130
V+ + EY+ + F V ++ +DL GID EA V++
Sbjct 78 KRVLNSPRAAGEYIRET-GNPKTFFVIRKEVKKDLEGIDF-------ERKISEA---VLI 126
Query 131 GSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTAT 190
G G ++++ L+ ++ + G ++A+H+ W T +GL +D G +++G+E A G A
Sbjct 127 GDIGEEWNYGILNDIFQKVKGGARLIALHKGKYWQTKEGLMLDIGTFVSGIEYATGVKAE 186
Query 191 AIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQTL 248
IGKP+ F AA + + +MIGDDL +DV AQ G+ GVLV+TGK+R + L
Sbjct 187 VIGKPSPAFFKAALKMISTQASETIMIGDDLDSDVGGAQVCGIRGVLVKTGKYRNEIL 244
>gi|71737277|ref|YP_276422.1| HAD superfamily hydrolase [Pseudomonas syringae pv. phaseolicola
1448A]
gi|71557830|gb|AAZ37041.1| hydrolase, HAD-superfamily, subfamily IIA [Pseudomonas syringae
pv. phaseolicola 1448A]
gi|115265573|dbj|BAF32835.1| HAD-superfamily hydrolase of subfamily IIA [Pseudomonas syringae
pv. actinidiae]
6 more sequence titles
Length=260
Score = 145 bits (367), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 97/272 (36%), Positives = 135/272 (50%), Gaps = 31/272 (11%)
Query 10 AVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLTNTTTRTRRQIAEALGAAGIPVA 69
A+L DIDG +V AIPGAAE + G+ +LTN T + IAE L GI V
Sbjct 5 ALLLDIDGTMVFKGHAIPGAAEAIEAARMAGLQLRFLTNITGQLPSTIAEDLQRHGINVR 64
Query 70 ADDVITAGVLTAEYLHGAYPGARCFLVNNGDITEDLPGI--DVVLSTEIGPEDCPEAPDV 127
A+++ TA A YL + CF + + GI D V +PDV
Sbjct 65 AEEIHTASTSCARYLK-SLGDVSCFFLMPESVNSMFEGIARDHV------------SPDV 111
Query 128 VVLGSAGPQFDHRTLSRVYGWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGK 187
VV+G G FD+ L++ +G++ G +V H+N+ W G+R+D G ++ G+E A GK
Sbjct 112 VVIGDIGESFDYACLNQAFGYLHKGARLVVPHKNLFWFDPRGVRLDCGAFILGLEAASGK 171
Query 188 TATAIGKPAAEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQT 247
A GKP+ F + D +GV P Q ++IGDDL D+ AAQ + + LV TGK
Sbjct 172 QALVTGKPSPVFFTSVMDSLGVKPSQTMIIGDDLLTDIAAAQHLEVAHALVLTGK----- 226
Query 248 LDRWLAGASAT-----RPHHVIDSVAGLPPLL 274
GAS T RP + S+A L L
Sbjct 227 ------GASYTESDVPRPERLWPSIAELSRFL 252
Lambda K H
0.321 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 435544382258
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40