BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1250 Length=579 Score E Sequences producing significant alignments: (Bits) Value gi|15608390|ref|NP_215766.1| drug-transport integral membrane pr... 1144 0.0 gi|31792443|ref|NP_854936.1| drug-transport integral membrane pr... 1141 0.0 gi|289749793|ref|ZP_06509171.1| drug-transport membrane protein ... 1139 0.0 gi|340626263|ref|YP_004744715.1| putative drug-transport integra... 1131 0.0 gi|308231792|ref|ZP_07663935.1| drug-transport membrane protein ... 1096 0.0 gi|254550257|ref|ZP_05140704.1| hypothetical protein Mtube_07324... 1094 0.0 gi|289569255|ref|ZP_06449482.1| drug-transport membrane protein ... 1080 0.0 gi|289761399|ref|ZP_06520777.1| conserved hypothetical protein [... 823 0.0 gi|240172270|ref|ZP_04750929.1| drug-transport integral membrane... 684 0.0 gi|41408632|ref|NP_961468.1| hypothetical protein MAP2534c [Myco... 683 0.0 gi|183984164|ref|YP_001852455.1| drug-transport integral membran... 682 0.0 gi|254821723|ref|ZP_05226724.1| hypothetical protein MintA_17447... 681 0.0 gi|342862127|ref|ZP_08718770.1| hypothetical protein MCOL_24671 ... 681 0.0 gi|296170152|ref|ZP_06851749.1| drug transporter [Mycobacterium ... 678 0.0 gi|118464957|ref|YP_880630.1| drug transporter [Mycobacterium av... 672 0.0 gi|254774267|ref|ZP_05215783.1| drug transporter [Mycobacterium ... 671 0.0 gi|126436559|ref|YP_001072250.1| EmrB/QacA family drug resistanc... 644 0.0 gi|108800934|ref|YP_641131.1| EmrB/QacA family drug resistance t... 640 0.0 gi|145222809|ref|YP_001133487.1| EmrB/QacA family drug resistanc... 640 0.0 gi|315443276|ref|YP_004076155.1| drug resistance transporter Emr... 635 9e-180 gi|118468657|ref|YP_889296.1| drug transporter [Mycobacterium sm... 625 9e-177 gi|333989858|ref|YP_004522472.1| drug-transport integral membran... 615 5e-174 gi|120405426|ref|YP_955255.1| EmrB/QacA family drug resistance t... 600 2e-169 gi|325676130|ref|ZP_08155811.1| drug transporter [Rhodococcus eq... 549 5e-154 gi|240168846|ref|ZP_04747505.1| drug-transport integral membrane... 548 1e-153 gi|312138486|ref|YP_004005822.1| mfs transporter [Rhodococcus eq... 529 6e-148 gi|226365491|ref|YP_002783274.1| drug resistance efflux protein ... 528 1e-147 gi|229493801|ref|ZP_04387579.1| multidrug efflux transport prote... 525 7e-147 gi|226307600|ref|YP_002767560.1| drug resistance efflux protein ... 525 1e-146 gi|240172791|ref|ZP_04751450.1| EmrB/QacA family drug resistance... 525 1e-146 gi|183983799|ref|YP_001852090.1| drug-transport integral membran... 523 3e-146 gi|111022986|ref|YP_705958.1| multidrug efflux transport protein... 516 5e-144 gi|343928045|ref|ZP_08767510.1| putative drug resistance efflux ... 515 8e-144 gi|326383546|ref|ZP_08205232.1| permease of the major facilitato... 512 6e-143 gi|262201828|ref|YP_003273036.1| EmrB/QacA subfamily drug resist... 510 3e-142 gi|119718568|ref|YP_925533.1| EmrB/QacA family drug resistance t... 509 5e-142 gi|336119081|ref|YP_004573855.1| putative drug resistance transp... 508 8e-142 gi|163841049|ref|YP_001625454.1| EmrB/QacA family drug resistanc... 496 4e-138 gi|116671551|ref|YP_832484.1| EmrB/QacA family drug resistance t... 494 1e-137 gi|331694707|ref|YP_004330946.1| EmrB/QacA subfamily drug resist... 492 8e-137 gi|326382060|ref|ZP_08203753.1| EmrB/QacA subfamily drug resista... 491 2e-136 gi|296138687|ref|YP_003645930.1| EmrB/QacA subfamily drug resist... 488 2e-135 gi|84497705|ref|ZP_00996527.1| albicidin efflux pump [Janibacter... 486 4e-135 gi|220913462|ref|YP_002488771.1| EmrB/QacA subfamily drug resist... 484 3e-134 gi|50955766|ref|YP_063054.1| albicidin efflux pump [Leifsonia xy... 482 8e-134 gi|183981892|ref|YP_001850183.1| drug-transport integral membran... 481 1e-133 gi|183983949|ref|YP_001852240.1| drug-transport integral membran... 480 3e-133 gi|317125848|ref|YP_004099960.1| drug resistance transporter Emr... 478 2e-132 gi|326331870|ref|ZP_08198157.1| drug transporter [Nocardioidacea... 477 2e-132 gi|323357646|ref|YP_004224042.1| permease of the major facilitat... 472 1e-130 >gi|15608390|ref|NP_215766.1| drug-transport integral membrane protein [Mycobacterium tuberculosis H37Rv] gi|15840696|ref|NP_335733.1| drug transporter [Mycobacterium tuberculosis CDC1551] gi|148661037|ref|YP_001282560.1| putative drug-transport integral membrane protein [Mycobacterium tuberculosis H37Ra] 30 more sequence titles Length=579 Score = 1144 bits (2959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 579/579 (100%), Positives = 579/579 (100%), Gaps = 0/579 (0%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT Sbjct 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG Sbjct 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV Sbjct 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV Sbjct 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV Sbjct 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG Sbjct 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA Sbjct 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA Sbjct 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 Query 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS Sbjct 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 Query 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL Sbjct 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 >gi|31792443|ref|NP_854936.1| drug-transport integral membrane protein [Mycobacterium bovis AF2122/97] gi|121637179|ref|YP_977402.1| putative drug-transport integral membrane protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989654|ref|YP_002644341.1| putative drug-transport integral membrane protein [Mycobacterium bovis BCG str. Tokyo 172] 14 more sequence titles Length=579 Score = 1141 bits (2951), Expect = 0.0, Method: Compositional matrix adjust. Identities = 578/579 (99%), Positives = 578/579 (99%), Gaps = 0/579 (0%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT Sbjct 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG Sbjct 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV Sbjct 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV Sbjct 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNL IAIIAFAGTGMMLPVTFYAQAV Sbjct 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG Sbjct 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA Sbjct 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA Sbjct 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 Query 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS Sbjct 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 Query 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL Sbjct 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 >gi|289749793|ref|ZP_06509171.1| drug-transport membrane protein [Mycobacterium tuberculosis T92] gi|289690380|gb|EFD57809.1| drug-transport membrane protein [Mycobacterium tuberculosis T92] Length=579 Score = 1139 bits (2945), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/579 (99%), Positives = 578/579 (99%), Gaps = 0/579 (0%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT Sbjct 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG Sbjct 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDS+GWEWIFFVNV Sbjct 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSIGWEWIFFVNV 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV Sbjct 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNL IAIIAFAGTGMMLPVTFYAQAV Sbjct 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG Sbjct 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA Sbjct 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA Sbjct 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 Query 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS Sbjct 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 Query 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL Sbjct 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 >gi|340626263|ref|YP_004744715.1| putative drug-transport integral membrane protein [Mycobacterium canettii CIPT 140010059] gi|340004453|emb|CCC43596.1| putative drug-transport integral membrane protein [Mycobacterium canettii CIPT 140010059] Length=579 Score = 1131 bits (2925), Expect = 0.0, Method: Compositional matrix adjust. Identities = 575/579 (99%), Positives = 577/579 (99%), Gaps = 0/579 (0%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT Sbjct 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG Sbjct 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLSTIT IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV Sbjct 121 AGLLTPQTLSTITWIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV Sbjct 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GGIGF+SLFVYWQARNAREPLIPLEVFNDRNFSLSNL IAIIAFAGTGMMLPVTFYAQAV Sbjct 241 GGIGFVSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIAIIAFAGTGMMLPVTFYAQAV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG Sbjct 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA Sbjct 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA Sbjct 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 Query 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS Sbjct 481 ALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRS 540 Query 541 GAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL 579 GAGGPLAVSWSTSA+GMPPGPPGRRAWQADTESTAPSAL Sbjct 541 GAGGPLAVSWSTSARGMPPGPPGRRAWQADTESTAPSAL 579 >gi|308231792|ref|ZP_07663935.1| drug-transport membrane protein [Mycobacterium tuberculosis SUMu001] gi|308370014|ref|ZP_07666845.1| drug-transport membrane protein [Mycobacterium tuberculosis SUMu002] gi|308370671|ref|ZP_07666989.1| drug-transport membrane protein [Mycobacterium tuberculosis SUMu003] 20 more sequence titles Length=556 Score = 1096 bits (2834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/556 (100%), Positives = 556/556 (100%), Gaps = 0/556 (0%) Query 24 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 83 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP Sbjct 1 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 60 Query 84 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 143 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV Sbjct 61 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 120 Query 144 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 203 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR Sbjct 121 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 180 Query 204 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 263 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP Sbjct 181 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 240 Query 264 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 323 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA Sbjct 241 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 300 Query 324 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 383 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP Sbjct 301 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 360 Query 384 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAG 443 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAG Sbjct 361 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAG 420 Query 444 QDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGD 503 QDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGD Sbjct 421 QDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGD 480 Query 504 ADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPG 563 ADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPG Sbjct 481 ADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPG 540 Query 564 RRAWQADTESTAPSAL 579 RRAWQADTESTAPSAL Sbjct 541 RRAWQADTESTAPSAL 556 >gi|254550257|ref|ZP_05140704.1| hypothetical protein Mtube_07324 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=555 Score = 1094 bits (2829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 555/555 (100%), Positives = 555/555 (100%), Gaps = 0/555 (0%) Query 25 MVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPK 84 MVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPK Sbjct 1 MVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPK 60 Query 85 NLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVA 144 NLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVA Sbjct 61 NLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVA 120 Query 145 LGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRF 204 LGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRF Sbjct 121 LGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRF 180 Query 205 DWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPL 264 DWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPL Sbjct 181 DWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPL 240 Query 265 EVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAP 324 EVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAP Sbjct 241 EVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAP 300 Query 325 FVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPL 384 FVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPL Sbjct 301 FVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPL 360 Query 385 TVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQ 444 TVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQ Sbjct 361 TVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQ 420 Query 445 DATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDA 504 DATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDA Sbjct 421 DATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDA 480 Query 505 DDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGR 564 DDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGR Sbjct 481 DDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGR 540 Query 565 RAWQADTESTAPSAL 579 RAWQADTESTAPSAL Sbjct 541 RAWQADTESTAPSAL 555 >gi|289569255|ref|ZP_06449482.1| drug-transport membrane protein [Mycobacterium tuberculosis T17] gi|289543009|gb|EFD46657.1| drug-transport membrane protein [Mycobacterium tuberculosis T17] Length=550 Score = 1080 bits (2794), Expect = 0.0, Method: Compositional matrix adjust. Identities = 549/550 (99%), Positives = 549/550 (99%), Gaps = 0/550 (0%) Query 30 MIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLI 89 MIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLI Sbjct 1 MIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLI 60 Query 90 GLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWG 149 GLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWG Sbjct 61 GLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWG 120 Query 150 TVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGV 209 TVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGV Sbjct 121 TVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGV 180 Query 210 GLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFND 269 GLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFND Sbjct 181 GLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFND 240 Query 270 RNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMI 329 RNFSLSNL IAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMI Sbjct 241 RNFSLSNLGIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMI 300 Query 330 IDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTAT 389 IDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTAT Sbjct 301 IDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTAT 360 Query 390 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVL 449 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVL Sbjct 361 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVL 420 Query 450 QLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADDDDY 509 QLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADDDDY Sbjct 421 QLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADDDDY 480 Query 510 VEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQA 569 VEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQA Sbjct 481 VEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQA 540 Query 570 DTESTAPSAL 579 DTESTAPSAL Sbjct 541 DTESTAPSAL 550 >gi|289761399|ref|ZP_06520777.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289708905|gb|EFD72921.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=420 Score = 823 bits (2127), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/420 (99%), Positives = 419/420 (99%), Gaps = 0/420 (0%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT Sbjct 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG Sbjct 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQ LSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV Sbjct 121 AGLLTPQALSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV Sbjct 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV Sbjct 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG Sbjct 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA Sbjct 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 >gi|240172270|ref|ZP_04750929.1| drug-transport integral membrane protein [Mycobacterium kansasii ATCC 12478] Length=593 Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/529 (70%), Positives = 414/529 (79%), Gaps = 10/529 (1%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MTTA R +SY +PW ALW+MM+GFFMIMLDST+VAIANPTIMA L +GYATVVWVT Sbjct 1 MTTATSRMPAASYSGSPWNALWSMMIGFFMIMLDSTIVAIANPTIMAVLHVGYATVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLL +AV +LVAGRLGDRFGPKNLYL GL VFT AS+ CGLS AG LI ARVVQGVG Sbjct 61 SAYLLGFAVVLLVAGRLGDRFGPKNLYLTGLAVFTAASMWCGLSGSAGALITARVVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLS ITR FPA RRGVA+ WG A VASLVGPLAGGALV +GWEWIFFVN+ Sbjct 121 AGLLTPQTLSIITRTFPAARRGVAMSMWGATAGVASLVGPLAGGALVGGLGWEWIFFVNI 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 P+GV+GL LAA+L+P LP RFD GV LSG GMFL+VFGLQ+G SA WQPWIWAV+V Sbjct 181 PIGVLGLALAAWLVPVLPVRAQRFDLIGVALSGIGMFLLVFGLQEGPSAGWQPWIWAVLV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 G+GFMS FVYWQ+ N PLIPLE+F DR+FSL + +AI AFA T MMLP+ FYAQ+V Sbjct 241 AGLGFMSAFVYWQSLNRHAPLIPLEIFRDRDFSLCTVGVAITAFATTAMMLPLIFYAQSV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSP A+L AP AI GVLAPFVG I+D SHPL V+GFGFS LAIAMTWL EM P Sbjct 301 CGLSPIRAALLIAPVAISSGVLAPFVGRIVDTSHPLPVVGFGFSALAIAMTWLSIEMEPD 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TP+WRLVLPF A+GV AFVWSPL TATRNLRP AGASSGV+NA RQ+GAVLGSASMA Sbjct 361 TPVWRLVLPFCAIGVGMAFVWSPLAATATRNLRPDQAGASSGVYNATRQIGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMTSRI+AEMP D G G + LQLPEFVR PF+AAMSQSMLLPAF+ALFGIVA Sbjct 421 AFMTSRISAEMPPPPDGAPG-FGGEGGGLQLPEFVRAPFSAAMSQSMLLPAFIALFGIVA 479 Query 481 ALFLVDFTGAAVAKEPLPESDGDADDDD---------YVEYILRREPEE 520 ALFLV TGA ++ LP+ D D + YVEYIL+ EP+ Sbjct 480 ALFLVGGTGATASRRLLPQGDHGDDYQESDEDFDDDDYVEYILQPEPDR 528 >gi|41408632|ref|NP_961468.1| hypothetical protein MAP2534c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396990|gb|AAS04851.1| hypothetical protein MAP_2534c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336458580|gb|EGO37547.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium avium subsp. paratuberculosis S397] Length=671 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/532 (69%), Positives = 411/532 (78%), Gaps = 28/532 (5%) Query 11 SSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVP 70 S++ +NPW LWAMM+GFFMIM+DST+VAIANPTIMA L IGY TVVWVTSAYLL YAV Sbjct 33 SAHSQNPWNPLWAMMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSAYLLGYAVV 92 Query 71 MLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLS 130 +LVAGRLGDRFG KNLYLIGL VFTVAS+ CGL+ A MLIAARVVQGVGAG+LTPQTLS Sbjct 93 LLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIAARVVQGVGAGVLTPQTLS 152 Query 131 TITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILA 190 TITRIFP RRGVA+ W A ASLVGPLAGG LVD +GW+WIFFVNVP+GV+GL LA Sbjct 153 TITRIFPPERRGVAVSVWSATAGAASLVGPLAGGVLVDGLGWQWIFFVNVPIGVLGLALA 212 Query 191 AYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFV 250 +L+P LP HRFD GVGLSG GMFLIVFGLQQGQ+A+WQPWIWA+IV G+GF+++FV Sbjct 213 YWLVPVLPTQSHRFDLVGVGLSGVGMFLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFV 272 Query 251 YWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAV 310 +WQ+ N REPLIPL +F DR+FSL N+ +AII+FA T MMLP+TFYAQAVCGLSPT +A+ Sbjct 273 FWQSVNVREPLIPLVIFADRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSAL 332 Query 311 LFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPF 370 L AP AI GV APFVG I+DR HP VLGFGFS+LAIA+TWL EM+P TPIWRLVLPF Sbjct 333 LIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSPATPIWRLVLPF 392 Query 371 IALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAE 430 A+GV AFVWSPLT TATRNL LAGA S V+N+VRQLGAVLGSA MAAFMT RI AE Sbjct 393 FAMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSAGMAAFMTWRIGAE 452 Query 431 MPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGA 490 MPG G+D+ LPEF+R PFAAAMSQS+LLPAF+ALFGIVAALFLV F Sbjct 453 MPGQPAG----GGEDSAGPVLPEFLRGPFAAAMSQSVLLPAFIALFGIVAALFLVGF--- 505 Query 491 AVAKEPLPESDGDAD-----------------DDDYVEYILRREPEEDCDTQ 525 P DG D DD YVE IL REPE + + Sbjct 506 ----RPWAHRDGGTDAFGPDDYGGDYDDDYDDDDAYVELILVREPEPEAQQR 553 >gi|183984164|ref|YP_001852455.1| drug-transport integral membrane protein [Mycobacterium marinum M] gi|183177490|gb|ACC42600.1| drug-transport integral membrane protein [Mycobacterium marinum M] Length=626 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/540 (68%), Positives = 409/540 (76%), Gaps = 23/540 (4%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MT R + Y NPW AL AMM+GFFMIMLDST+V+IANPTIMA+L IGYA VVWVT Sbjct 1 MTAVTSRVLDNGYSGNPWNALSAMMIGFFMIMLDSTIVSIANPTIMAELHIGYADVVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLL YAV +LVAGRLGDRFGPKNLYLIGL VFT AS+ CGL+ A MLIAAR VQG+G Sbjct 61 SAYLLGYAVVLLVAGRLGDRFGPKNLYLIGLSVFTAASMWCGLAGTAAMLIAARTVQGIG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 AGLLTPQTLSTITRIFPA RRG AL WG A VASLVGPL GG LV +GWEWIFFVN+ Sbjct 121 AGLLTPQTLSTITRIFPATRRGAALSLWGAAAGVASLVGPLIGGVLVSGLGWEWIFFVNI 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 P+G+ GL++A L+P LP H RFD GVGLSGAGMFL+VFGLQ+GQ+A+W PWIWAV+V Sbjct 181 PIGLAGLVVAYLLVPDLPVHAQRFDLIGVGLSGAGMFLLVFGLQEGQAADWAPWIWAVLV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 G+GFM++FVYWQA N R PLI L +F D FSL N+ + I AFA T MLP+TFYAQ+V Sbjct 241 AGVGFMAMFVYWQALNHRAPLISLAIFRDWEFSLCNIGVGITAFATTAPMLPLTFYAQSV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 CGLSP AVL AP A+ GVLAP VGM++DRSHPL VLGFGFS LAI+MTWL EM P Sbjct 301 CGLSPARAAVLIAPVALASGVLAPVVGMLVDRSHPLPVLGFGFSALAISMTWLSIEMVPE 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TP+WRLVLPF A+G AFVWSPL TATRNL HLAGA SGV+NA RQLGAVLGSASMA Sbjct 361 TPVWRLVLPFAAMGAGMAFVWSPLAATATRNLPAHLAGAGSGVYNATRQLGAVLGSASMA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 AFMT RI AEMP G DA G +G D LQLPE VR PF+AAMSQSMLLPAF+A+FGI+A Sbjct 421 AFMTWRITAEMPPGFDADRGFSGGDGG-LQLPEVVRTPFSAAMSQSMLLPAFIAVFGIIA 479 Query 481 ALFLVDFTGAAV-AKEPLPESD--------------GDADD-------DDYVEYILRREP 518 ALFLV A V A + +D G+ DD DDYVE++LR EP Sbjct 480 ALFLVRSRTAPVRAHDRASHADDDHVDRGDYGYGDYGEQDDFGEQDDYDDYVEFVLRPEP 539 >gi|254821723|ref|ZP_05226724.1| hypothetical protein MintA_17447 [Mycobacterium intracellulare ATCC 13950] Length=663 Score = 681 bits (1758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/482 (73%), Positives = 396/482 (83%), Gaps = 12/482 (2%) Query 11 SSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVP 70 S + +NPW LWAMM+GFFMIM+DST+VAIANPTIMA LRIGY TVVWVTSAYLL YAV Sbjct 26 SPHSQNPWNPLWAMMIGFFMIMVDSTIVAIANPTIMANLRIGYDTVVWVTSAYLLGYAVV 85 Query 71 MLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLS 130 +LVAGRLGDRFGPKNLYLIGL VFTV+S+ CGLS A MLIAARV QG+GAG+LTPQTLS Sbjct 86 LLVAGRLGDRFGPKNLYLIGLVVFTVSSVWCGLSGSAAMLIAARVAQGIGAGVLTPQTLS 145 Query 131 TITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILA 190 TITRIFP RRG+A+ WG A ASLVGPLAGG LVD +GW+WIFFVNVPVGVIGL LA Sbjct 146 TITRIFPPERRGIAVSLWGATAGAASLVGPLAGGVLVDGLGWQWIFFVNVPVGVIGLALA 205 Query 191 AYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFV 250 +LIP LP HRFD GVGLSG GMFLIVFGLQQGQ+A+W+PWIWA+IV G GFM++FV Sbjct 206 YWLIPVLPTQSHRFDLIGVGLSGVGMFLIVFGLQQGQAAHWEPWIWALIVAGFGFMTVFV 265 Query 251 YWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAV 310 +WQ+ N EPLIPL +F DR+FSL N+ +AI++F T MMLP+TFYAQAVCGLSPT +A+ Sbjct 266 FWQSVNPHEPLIPLVIFGDRDFSLCNVGVAIVSFTATAMMLPLTFYAQAVCGLSPTRSAL 325 Query 311 LFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPF 370 L AP AI GV APFVG I+D HP VLGFGFSVLAIA+TWL +M+P TPIWRLVLPF Sbjct 326 LIAPMAIANGVFAPFVGKIVDNYHPRPVLGFGFSVLAIALTWLTFDMSPTTPIWRLVLPF 385 Query 371 IALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAE 430 A+GV AFVWSPLT TATRNL HLAGA S V+N+VRQLGAVLGSA MAAFMT RI AE Sbjct 386 FAMGVGMAFVWSPLTATATRNLPAHLAGAGSAVYNSVRQLGAVLGSAGMAAFMTWRITAE 445 Query 431 MP-----GGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLV 485 MP GG+D +DA LQLP F+REPFAAAMSQS+LLPAF+ALFGI+AALFLV Sbjct 446 MPRRPAGGGID-------EDAATLQLPRFLREPFAAAMSQSVLLPAFIALFGIIAALFLV 498 Query 486 DF 487 F Sbjct 499 GF 500 >gi|342862127|ref|ZP_08718770.1| hypothetical protein MCOL_24671 [Mycobacterium colombiense CECT 3035] gi|342130431|gb|EGT83746.1| hypothetical protein MCOL_24671 [Mycobacterium colombiense CECT 3035] Length=644 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/472 (75%), Positives = 393/472 (84%), Gaps = 4/472 (0%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 NPW LWAMM+GFFMIM+DST+VAIANPTIMA LRIGY TVVWVTSAYLL YAV +LVA Sbjct 20 HNPWNPLWAMMIGFFMIMVDSTIVAIANPTIMASLRIGYDTVVWVTSAYLLGYAVVLLVA 79 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDRFGPKNLYL GL VFT +S+ CGL+ A MLIAARVVQGVGAGLLTPQTLSTITR Sbjct 80 GRLGDRFGPKNLYLFGLVVFTASSVWCGLAGSAAMLIAARVVQGVGAGLLTPQTLSTITR 139 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 IFP+ RRGVA+ WG A VASLVGPLAGG LVD +GW+WIFFVNVP+GVIGL+LA +L+ Sbjct 140 IFPSERRGVAVSLWGATAGVASLVGPLAGGVLVDGLGWQWIFFVNVPIGVIGLVLAYWLV 199 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQA 254 P LP HRFD GV LSG G+FLIVFGLQQGQ+A+WQPWIWA+IV G+GFM+ F +WQA Sbjct 200 PVLPTQLHRFDLIGVALSGIGIFLIVFGLQQGQAAHWQPWIWALIVAGVGFMTAFAFWQA 259 Query 255 RNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAP 314 NA EPLIPL +F DR+FSL N +AII+F T MMLP+TFYAQAVCGLSPT +A+L AP Sbjct 260 LNAHEPLIPLIIFGDRDFSLCNAGVAIISFTATAMMLPLTFYAQAVCGLSPTRSALLIAP 319 Query 315 TAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALG 374 AI GV APFVG I+D+ HP VLGFGFSVLAIA+TWL EM P TPIWRLVLPF A+G Sbjct 320 MAIANGVFAPFVGKIVDKYHPQPVLGFGFSVLAIALTWLTFEMLPTTPIWRLVLPFFAMG 379 Query 375 VAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGG 434 V AFVWSPLT TATRNL PHLAGA S V+N+VRQLGAVLGSA MAAFMT RI AEMP Sbjct 380 VGMAFVWSPLTATATRNLPPHLAGAGSAVYNSVRQLGAVLGSAGMAAFMTWRITAEMP-- 437 Query 435 VDALTGPA-GQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLV 485 +G A G+DA LQLP F+REPF+AAMSQS+LLPAF+ALFGIVAALFLV Sbjct 438 -RQPSGDATGEDAIALQLPGFLREPFSAAMSQSVLLPAFIALFGIVAALFLV 488 >gi|296170152|ref|ZP_06851749.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895178|gb|EFG74893.1| drug transporter [Mycobacterium parascrofulaceum ATCC BAA-614] Length=656 Score = 678 bits (1750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/482 (73%), Positives = 395/482 (82%), Gaps = 10/482 (2%) Query 10 GSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAV 69 S + PW ALWAMM+GFFMIM+DST+VAIANPTIM LRIGY TVVWVTSAYLL YAV Sbjct 32 NSPQSQKPWNALWAMMIGFFMIMVDSTIVAIANPTIMTSLRIGYDTVVWVTSAYLLGYAV 91 Query 70 PMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTL 129 +LVAGRLGDRFGPKNLYLIGL VFT AS+ CGL+ A MLIAARVVQGVGAG+LTPQTL Sbjct 92 VLLVAGRLGDRFGPKNLYLIGLVVFTAASVWCGLADSAAMLIAARVVQGVGAGVLTPQTL 151 Query 130 STITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLIL 189 STITRIFP RRGVA+ WG A VASLVGPLAGG LVD +GW+WIFFVNVP+GV GL L Sbjct 152 STITRIFPPERRGVAVSLWGATAGVASLVGPLAGGVLVDGLGWQWIFFVNVPIGVAGLAL 211 Query 190 AAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLF 249 A +L+P LP HRFD GV LSGAGMFLIVFGLQQGQ+A+W+PWIWA+IV GIGFM++F Sbjct 212 AYWLVPVLPTQSHRFDLVGVALSGAGMFLIVFGLQQGQAAHWEPWIWAMIVAGIGFMTVF 271 Query 250 VYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA 309 V+WQ+ N EPLIPL +F DR+F L N +A+++FA T MMLP+TFYAQAVCGLSPT +A Sbjct 272 VFWQSMNTDEPLIPLVIFRDRDFGLCNAGVAVVSFAATAMMLPLTFYAQAVCGLSPTRSA 331 Query 310 VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP 369 +L AP AI GV APFVG ++DR HP VLGFGFSVLAIA+TWL EM+P TPIWRLVLP Sbjct 332 LLIAPMAIANGVFAPFVGRMVDRYHPRPVLGFGFSVLAIALTWLTFEMSPETPIWRLVLP 391 Query 370 FIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAA 429 F A GV AFVWSPLT TATRNL P LAGA S V+N+VRQLGAVLGSA MAAFMT+RI A Sbjct 392 FFATGVGMAFVWSPLTATATRNLPPGLAGAGSAVYNSVRQLGAVLGSAGMAAFMTARIGA 451 Query 430 EM----PGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLV 485 +M PGG + G+ A LQLPEF+R+PFAAAMSQS+LLPAFVALFGIVAALFLV Sbjct 452 QMPPRPPGGAE------GEAAASLQLPEFLRDPFAAAMSQSVLLPAFVALFGIVAALFLV 505 Query 486 DF 487 F Sbjct 506 GF 507 >gi|118464957|ref|YP_880630.1| drug transporter [Mycobacterium avium 104] gi|118166244|gb|ABK67141.1| drug transporter [Mycobacterium avium 104] Length=626 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/526 (68%), Positives = 406/526 (78%), Gaps = 28/526 (5%) Query 24 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 83 MM+GFFMIM+DST+VAIANPTIMA L IGY TVVWVTSAYLL YAV +LVAGRLGDRFG Sbjct 1 MMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSAYLLGYAVVLLVAGRLGDRFGT 60 Query 84 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 143 KNLYLIGL VFTVAS+ CGL+ A MLIAARVVQGVGAG++TPQTLSTITRIFPA RRGV Sbjct 61 KNLYLIGLAVFTVASVWCGLAGSAAMLIAARVVQGVGAGVMTPQTLSTITRIFPAERRGV 120 Query 144 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 203 A+ W A ASL GPLAGG LVD +GW+WIFFVNVP+GV+GL+LA +L+P LP HR Sbjct 121 AVSVWSATAGAASLAGPLAGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLPTQSHR 180 Query 204 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 263 FD GVGLSG GM LIVFGLQQGQ+A+WQPWIWA+IV G+GF+++FV+WQ+ N REPLIP Sbjct 181 FDLVGVGLSGVGMLLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVREPLIP 240 Query 264 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 323 L +F+DR+FSL N+ +AII+FA T MMLP+TFYAQAVCGLSPT +A+L AP AI GV A Sbjct 241 LVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSALLIAPMAIANGVFA 300 Query 324 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 383 PFVG I+DR HP VLGFGFS+LAIA+TWL EM+P TPIWRLVLPF A+GV AFVWSP Sbjct 301 PFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSPATPIWRLVLPFFAMGVGMAFVWSP 360 Query 384 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAG 443 LT TATRNL LAGA S V+N+VRQLGAVLGSA MAAFMT RI AEMPG G G Sbjct 361 LTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSAGMAAFMTWRIGAEMPG----QPGGGG 416 Query 444 QDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGD 503 +D+ LPEF+R PFAAAMSQS+LLPAF+ALFGIVAALFLV F P DG Sbjct 417 EDSAGPVLPEFLRGPFAAAMSQSVLLPAFIALFGIVAALFLVGF-------RPWAHRDGG 469 Query 504 AD-----------------DDDYVEYILRREPEEDCDTQPLRASRP 532 D DD YVE IL REPE + + + RP Sbjct 470 TDAFGPDDYGGDYHDDYDDDDAYVELILVREPEPEAQQRAGQPRRP 515 >gi|254774267|ref|ZP_05215783.1| drug transporter [Mycobacterium avium subsp. avium ATCC 25291] Length=626 Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/526 (69%), Positives = 405/526 (77%), Gaps = 28/526 (5%) Query 24 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 83 MM+GFFMIM+DST+VAIANPTIMA L IGY TVVWVTSAYLL YAV +LVAGRLGDRFG Sbjct 1 MMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSAYLLGYAVVLLVAGRLGDRFGT 60 Query 84 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 143 KNLYLIGL VFTVAS+ CGL+ A MLIAARVVQGVGAG+LTPQTLSTITRIFPA RRGV Sbjct 61 KNLYLIGLAVFTVASVWCGLAGSAAMLIAARVVQGVGAGVLTPQTLSTITRIFPAERRGV 120 Query 144 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 203 A+ W A ASL GPLAGG LVD +GW+WIFFVNVP+GV+GL+LA +L+P LP HR Sbjct 121 AVSVWSATAGAASLAGPLAGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLPTQSHR 180 Query 204 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 263 FD GVGLSG GMFLIVFGLQQGQ+A+WQPWIWA+IV G+GF+++FV+WQ+ N REPLIP Sbjct 181 FDLVGVGLSGVGMFLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVREPLIP 240 Query 264 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 323 L +F DR+FSL + +AII+FA T MMLP+TFYAQAVCGLSPT +A+L AP AI GV A Sbjct 241 LVIFADRDFSLCTIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSALLIAPMAIANGVFA 300 Query 324 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 383 PFVG I+DR HP VLGFGFS+LAIA+TWL EM+P TPIWRLVLPF A+GV AFVWSP Sbjct 301 PFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMSPATPIWRLVLPFFAMGVGMAFVWSP 360 Query 384 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAG 443 LT TATRNL LAGA S V+N+VRQLGAVLGSA MAAFMT RI AEMPG G G Sbjct 361 LTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSAGMAAFMTWRIGAEMPG----QPGGGG 416 Query 444 QDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGD 503 +D+ LPEF+R PFAAAMSQS+LLPAF+ALFGIVAALFLV F P DG Sbjct 417 EDSAGPVLPEFLRGPFAAAMSQSVLLPAFIALFGIVAALFLVGF-------RPWAHRDGG 469 Query 504 AD-----------------DDDYVEYILRREPEEDCDTQPLRASRP 532 D DD YVE IL REPE + + + RP Sbjct 470 TDAFGPDDYGGDYHDDYDDDDAYVELILVREPEPEAQQRAGQPRRP 515 >gi|126436559|ref|YP_001072250.1| EmrB/QacA family drug resistance transporter [Mycobacterium sp. JLS] gi|126236359|gb|ABN99759.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium sp. JLS] Length=646 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/577 (61%), Positives = 408/577 (71%), Gaps = 33/577 (5%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 +PW ALWAMMVGFFMI++D+T+VA+ANP +M ++ Y V+WVTSAYLLAYAVP+LVAG Sbjct 13 DPWHALWAMMVGFFMILVDATIVAVANPVLMEKMGADYDAVIWVTSAYLLAYAVPLLVAG 72 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGPKN+YL+GL VFT ASL CGL+ LIAARVVQGVGA LLTPQTLSTITRI Sbjct 73 RLGDRFGPKNVYLVGLAVFTAASLWCGLAGSIDTLIAARVVQGVGAALLTPQTLSTITRI 132 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FP RRGVA+ WG A VA+LVGPLAGG LVD +GW+WIFFVNVPVGV GL LA + +P Sbjct 133 FPPERRGVAMSVWGATAGVATLVGPLAGGVLVDHLGWQWIFFVNVPVGVAGLALAFWRVP 192 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 AL HRFD GV LSG GMF IVFGLQ+GQS WQPWIW VIV G+ M+ FVYWQ+ Sbjct 193 ALTTTAHRFDLLGVLLSGVGMFAIVFGLQEGQSHGWQPWIWVVIVAGVAVMAGFVYWQSV 252 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N EPLIPL +F DR+FSLS+ +A+I F TGM++P F+AQAVCGLSPT +A+L AP Sbjct 253 NPHEPLIPLRIFGDRDFSLSSFGVAVIGFVVTGMIVPAMFFAQAVCGLSPTESALLTAPM 312 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 AI GVLAP VG I+DR+HP ++GFGFS LAI +TWL EM P TPIWRLVLPF+ +G+ Sbjct 313 AIASGVLAPAVGRIVDRAHPRPIVGFGFSALAIGLTWLSIEMTPDTPIWRLVLPFLVMGI 372 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 AF+WSPL TATRNL PHLAGA SGV+NA RQ+G+VLGSA MAAFMTSRI+AEMP Sbjct 373 GMAFIWSPLAATATRNLAPHLAGAGSGVYNATRQVGSVLGSAGMAAFMTSRISAEMP--- 429 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKE 495 A G + V LPEF++ PFAAAMSQS+LLPAFVAL G+VAA+FL F GA+ Sbjct 430 SAQGGAPRGEGAVSALPEFLQVPFAAAMSQSLLLPAFVALIGVVAAIFLRGFGGASAPVV 489 Query 496 PLPESDGDADDDD-----------YVEYI-----------LRREPE---EDCDTQPLRAS 530 P + D DD Y+EY + PE +D T PL Sbjct 490 AAPVARADHRDDSVDDSHGYDDDDYLEYAVSWDDLQFTEPISTRPEVGADDSVTAPLATR 549 Query 531 -RPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRA 566 R A AAA SGA P W + P PP R A Sbjct 550 GRRAEAAAEPSGADDP----WRRVLDELLPEPPARPA 582 >gi|108800934|ref|YP_641131.1| EmrB/QacA family drug resistance transporter [Mycobacterium sp. MCS] gi|119870074|ref|YP_940026.1| EmrB/QacA family drug resistance transporter [Mycobacterium sp. KMS] gi|108771353|gb|ABG10075.1| Drug resistance transporter EmrB/QacA subfamily [Mycobacterium sp. MCS] gi|119696163|gb|ABL93236.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium sp. KMS] Length=646 Score = 640 bits (1651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/575 (61%), Positives = 405/575 (71%), Gaps = 33/575 (5%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 +PW ALWAMMVGFFMI++D+T+VA+ANP +M +L Y V+WVTSAYLLAYAVP+LVAG Sbjct 13 DPWHALWAMMVGFFMILVDATIVAVANPVLMEKLGADYDAVIWVTSAYLLAYAVPLLVAG 72 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGPKN+YL+GL VFT ASL CGL+ LIAARVVQGVGA LLTPQTLSTITRI Sbjct 73 RLGDRFGPKNVYLVGLAVFTAASLWCGLAGSIDTLIAARVVQGVGAALLTPQTLSTITRI 132 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FP RRGVA+ WG A VA+LVGPLAGG LVD +GW+WIFFVNVPVGV GL LA + +P Sbjct 133 FPPERRGVAMSVWGATAGVATLVGPLAGGVLVDHLGWQWIFFVNVPVGVAGLALAFWRVP 192 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 AL HRFD GV LSG GMF IVFGLQ+GQS WQPWIW VIV G+ M+ FVYWQ+ Sbjct 193 ALTTTAHRFDLLGVLLSGVGMFAIVFGLQEGQSHGWQPWIWVVIVAGVAVMAGFVYWQSV 252 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N EPLIPL +F DR+FSLS+ +A+I F TGM++P F+AQAVCGLSPT +A+L AP Sbjct 253 NPHEPLIPLRIFGDRDFSLSSFGVAVIGFVVTGMIVPAMFFAQAVCGLSPTESALLTAPM 312 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 AI GVLAP VG I+DR+HP ++GFGFS LAI +TWL EM P TPIWRLVLPF+ +G+ Sbjct 313 AITSGVLAPAVGRIVDRAHPRPIVGFGFSALAIGLTWLSIEMTPDTPIWRLVLPFLVMGI 372 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 AF+WSPL TATRNL PHLAGA SGV+NA RQ+G+VLGSA MAAFMTSRI+AEMP Sbjct 373 GMAFIWSPLAATATRNLAPHLAGAGSGVYNATRQVGSVLGSAGMAAFMTSRISAEMP--- 429 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKE 495 A G + V LPEF++ PFAAAMSQS+LLPAFVAL G+VAA+FL F + Sbjct 430 SAQGGAPRGEGAVSALPEFLQVPFAAAMSQSLLLPAFVALIGVVAAIFLRGFGEVSAPVV 489 Query 496 PLPESDGDADDDD-----------YVEYI-----------LRREPE---EDCDTQPLRAS 530 P + D DD Y+EY + PE +D T PL Sbjct 490 AAPVARADPRDDSVDDSHGYDDDDYLEYAVSWDDLQFTEPISTRPEVGADDSVTTPLATR 549 Query 531 -RPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGR 564 R A AAA SGA P W + P PP R Sbjct 550 GRRAEAAAEPSGADDP----WRRVLDELLPEPPAR 580 >gi|145222809|ref|YP_001133487.1| EmrB/QacA family drug resistance transporter [Mycobacterium gilvum PYR-GCK] gi|145215295|gb|ABP44699.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium gilvum PYR-GCK] Length=609 Score = 640 bits (1650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/537 (62%), Positives = 405/537 (76%), Gaps = 21/537 (3%) Query 3 TAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA 62 T RAAG++ NPWPALWA+++GFFMI++D+T+VA+ANP IMA L GY V+WVTSA Sbjct 4 TVTSRAAGTT---NPWPALWALLIGFFMILVDATIVAVANPAIMASLNAGYDAVIWVTSA 60 Query 63 YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAG 122 YLLAYAVP+LV+GRLGDR+GPKN+Y++GL VFTVASL CGLS GMLIAARVVQGVGA Sbjct 61 YLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLSDSIGMLIAARVVQGVGAA 120 Query 123 LLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPV 182 LLTPQT++ ITR FPAHRRGVA+ WG A VA+LVGPLAGG LVDS+GW+WIF VNVPV Sbjct 121 LLTPQTMTVITRTFPAHRRGVAMSVWGATAGVATLVGPLAGGVLVDSLGWQWIFIVNVPV 180 Query 183 GVIGLILAAYLIPALPHHPHR-FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVG 241 G++GL++A L+PALP+ + FD GV LSG G+FLIVF LQ+GQS W WIWA ++ Sbjct 181 GIVGLVMALRLVPALPNPVRQGFDVPGVVLSGVGLFLIVFALQEGQSHGWALWIWATVLA 240 Query 242 GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVC 301 G+ M+ FVYWQ+ N LIPL +F DRNFS+SNL +A I F TGM+LP+ F+AQAVC Sbjct 241 GVAVMAAFVYWQSINTAGALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAVC 300 Query 302 GLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGT 361 GL+PT A+L AP A+ GVLAPFVG ++DR+HP V+GFGFS++AI +TWL EM P T Sbjct 301 GLTPTRAALLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGVTWLSIEMTPTT 360 Query 362 PIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAA 421 PIWRL+LP A+G A AF+WSPL TATRNL PHLAGA SGV+N RQ+G+VLGSA MAA Sbjct 361 PIWRLLLPLTAMGAAMAFIWSPLAATATRNLPPHLAGAGSGVYNTTRQVGSVLGSAGMAA 420 Query 422 FMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAA 481 M+S ++ ++PG DA+ G+ V LP+F+REPFA AMSQSMLLPAFVALFG++AA Sbjct 421 LMSSELSTKIPGA-DAVPQSEGE---VAALPQFLREPFALAMSQSMLLPAFVALFGVIAA 476 Query 482 LFLVDFTGAAVAK-------EPLPESDGD-----AD-DDDYVEYILRREPEEDCDTQ 525 LFL D G A EPL D D AD +DDYVEY + RE + T Sbjct 477 LFLFDLLGDRDAAAPPAPDVEPLEPFDPDHPLDWADGEDDYVEYEVSREEFDRLATD 533 >gi|315443276|ref|YP_004076155.1| drug resistance transporter EmrB/QacA subfamily [Mycobacterium sp. Spyr1] gi|315261579|gb|ADT98320.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium sp. Spyr1] Length=609 Score = 635 bits (1637), Expect = 9e-180, Method: Compositional matrix adjust. Identities = 331/537 (62%), Positives = 404/537 (76%), Gaps = 21/537 (3%) Query 3 TAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSA 62 T RAAG++ NPWPAL A+++GFFMI++D+T+VA+ANP IMA L GY V+WVTSA Sbjct 4 TVTSRAAGTT---NPWPALGALLIGFFMILVDATIVAVANPAIMASLNAGYDAVIWVTSA 60 Query 63 YLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAG 122 YLLAYAVP+LV+GRLGDR+GPKN+Y++GL VFTVASL CGLS GMLIAARVVQGVGA Sbjct 61 YLLAYAVPLLVSGRLGDRYGPKNVYMVGLTVFTVASLWCGLSDSIGMLIAARVVQGVGAA 120 Query 123 LLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPV 182 LLTPQT++ ITR FPAHRRGVA+ WG A VA+LVGPLAGG LVDS+GW+WIF VNVPV Sbjct 121 LLTPQTMTVITRTFPAHRRGVAMSVWGATAGVATLVGPLAGGVLVDSLGWQWIFIVNVPV 180 Query 183 GVIGLILAAYLIPALPHHPHR-FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVG 241 G++GL++A L+PALP+ + FD GV LSG G+FLIVF LQ+GQS W WIWA ++ Sbjct 181 GIVGLVMALRLVPALPNPVRQGFDVPGVVLSGVGLFLIVFALQEGQSHGWALWIWATVLA 240 Query 242 GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVC 301 G+ M+ FVYWQ+ N LIPL +F DRNFS+SNL +A I F TGM+LP+ F+AQAVC Sbjct 241 GVAVMAAFVYWQSINTAGALIPLVIFRDRNFSMSNLGVATIGFVATGMILPLMFFAQAVC 300 Query 302 GLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGT 361 GL+PT A+L AP A+ GVLAPFVG ++DR+HP V+GFGFS++AI +TWL EM P T Sbjct 301 GLTPTRAALLTAPMAVATGVLAPFVGKLVDRAHPRSVVGFGFSLMAIGVTWLSIEMTPTT 360 Query 362 PIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAA 421 PIWRL+LP A+G A AF+WSPL TATRNL PHLAGA SGV+N RQ+G+VLGSA MAA Sbjct 361 PIWRLLLPLTAMGAAMAFIWSPLAATATRNLPPHLAGAGSGVYNTTRQVGSVLGSAGMAA 420 Query 422 FMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAA 481 M+S ++ ++PG DA+ G+ V LP+F+REPFA AMSQSMLLPAFVALFG++AA Sbjct 421 LMSSELSTKIPGA-DAVPQSEGE---VAALPQFLREPFALAMSQSMLLPAFVALFGVIAA 476 Query 482 LFLVDFTGAAVAK-------EPLPESDGD-----AD-DDDYVEYILRREPEEDCDTQ 525 LFL D G A EPL D D AD +DDYVEY + RE + T Sbjct 477 LFLFDLLGDRDAAAPPAPDVEPLEPFDPDHPLDWADGEDDYVEYEVSREEFDRLATD 533 >gi|118468657|ref|YP_889296.1| drug transporter [Mycobacterium smegmatis str. MC2 155] gi|118169944|gb|ABK70840.1| drug transporter [Mycobacterium smegmatis str. MC2 155] Length=568 Score = 625 bits (1611), Expect = 9e-177, Method: Compositional matrix adjust. Identities = 323/501 (65%), Positives = 389/501 (78%), Gaps = 4/501 (0%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 NPW ALWAMM GFFMI++D+T+V++ANPTIM +L Y V+WVTSAYLLAYAVP+LV G Sbjct 28 NPWNALWAMMFGFFMILVDATIVSVANPTIMVELGADYDGVIWVTSAYLLAYAVPLLVTG 87 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGD +GPKNLYL+GLGVFT ASL CGL+ MLIAARVVQG+GA LLTPQTLS ITRI Sbjct 88 RLGDMYGPKNLYLLGLGVFTAASLWCGLAGSIEMLIAARVVQGIGAALLTPQTLSAITRI 147 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FPA+RRGVA+ WG A VA+LVGPLAGG LV +GW+WIFFVNVPVG++G+ LA +L+P Sbjct 148 FPANRRGVAMSVWGATAGVATLVGPLAGGVLVGGLGWQWIFFVNVPVGIVGIALAVWLVP 207 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 LP H FD G+ LS GMFLIVF LQ+GQS +W PW+W G+G M+ F +WQ+ Sbjct 208 TLPTTRHHFDIPGIVLSAVGMFLIVFALQEGQSKDWAPWVWGTATLGVGVMAAFFFWQSV 267 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N REPLIPL VF DR+F+L+N+ +A+I FA T M+LP+ FY Q VCGLSP +A++ APT Sbjct 268 NTREPLIPLRVFADRDFTLANIGVAVIGFAVTAMILPLMFYLQTVCGLSPIRSALVTAPT 327 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 AI GVLAPFVG I+DR HP+ V+GFGFS +AI +TWL EMAP TPIWRL+LP + +G+ Sbjct 328 AIASGVLAPFVGRIVDRVHPMPVIGFGFSAMAIGLTWLSIEMAPTTPIWRLLLPQLLMGI 387 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 AF+WSPL TATR+L P LAGA SGV+N RQ+G+VLGSA +AAFMT RI E+PG Sbjct 388 GMAFIWSPLAATATRHLPPDLAGAGSGVYNTTRQVGSVLGSAGIAAFMTWRITDEVPGMQ 447 Query 436 DALTGPAGQD-ATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAK 494 DA PAG+ V QLPEF+REPF+AAMSQ+MLLPAF+ALFG+VAALFL+ F A Sbjct 448 DA--APAGESGGAVEQLPEFLREPFSAAMSQAMLLPAFIALFGVVAALFLLGFGSNRAAG 505 Query 495 EPLPESDGD-ADDDDYVEYIL 514 P PE GD DDD+YVE IL Sbjct 506 HPEPEHAGDYPDDDEYVEIIL 526 >gi|333989858|ref|YP_004522472.1| drug-transport integral membrane protein [Mycobacterium sp. JDM601] gi|333485826|gb|AEF35218.1| drug-transport integral membrane protein [Mycobacterium sp. JDM601] Length=676 Score = 615 bits (1587), Expect = 5e-174, Method: Compositional matrix adjust. Identities = 313/478 (66%), Positives = 373/478 (79%), Gaps = 10/478 (2%) Query 24 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 83 MM+GFF+I++DST+VA+ANP+IMA L +GY TV+WVTSAYLL YAVP+LV GRLGD+FGP Sbjct 1 MMLGFFVILVDSTIVAVANPSIMAALDVGYDTVIWVTSAYLLGYAVPLLVTGRLGDQFGP 60 Query 84 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 143 KNLYL GL VFT ASL CGL+ G MLI AR VQG+GA LLTPQTL+ ITR FPA RRG+ Sbjct 61 KNLYLAGLAVFTGASLWCGLAGGIDMLITARAVQGIGAALLTPQTLTVITRTFPADRRGM 120 Query 144 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 203 A+ WG A VA+L+GPLAGG LVD +GWEWIFFVNVPVGV+G+ILA LIP LP H HR Sbjct 121 AMSVWGATAGVATLIGPLAGGVLVDGLGWEWIFFVNVPVGVLGMILAYVLIPDLPVHRHR 180 Query 204 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 263 FD GV LSG GMFL+VF LQ+G+S W PWIWA+IVGG+G ++LFVYWQA EPL+P Sbjct 181 FDLIGVALSGIGMFLLVFALQEGESQGWAPWIWALIVGGVGCLALFVYWQAVTGGEPLVP 240 Query 264 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 323 L +F D +F L+N+ +A+I FA T M+LPV FYAQAVCG+SPT A+L AP AI GVLA Sbjct 241 LHIFRDLDFGLANIGVAVIGFAATAMVLPVMFYAQAVCGMSPTRAALLTAPMAIASGVLA 300 Query 324 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 383 P VG I+DR+HP ++GFGFS+LAIA+TWL EM P TP+WRL+LPF A+G+ AF+WSP Sbjct 301 PVVGKIVDRAHPRTMVGFGFSMLAIALTWLSIEMTPVTPVWRLLLPFTAVGIGMAFIWSP 360 Query 384 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAE---MPGGVDALTG 440 L TATRNL PHLAGA SGV+NA RQ+GAVLGSA MAAFMTSRI+ MPGG+ +G Sbjct 361 LAATATRNLPPHLAGAGSGVYNATRQIGAVLGSAGMAAFMTSRISTNLPPMPGGLHPGSG 420 Query 441 PAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLP 498 LP+F+ EPFAAAMS+S LLPAFV LFG+VAALF+V F A + P Sbjct 421 NR-------NLPDFLHEPFAAAMSESTLLPAFVTLFGVVAALFMVGFVIAPARRTARP 471 >gi|120405426|ref|YP_955255.1| EmrB/QacA family drug resistance transporter [Mycobacterium vanbaalenii PYR-1] gi|119958244|gb|ABM15249.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium vanbaalenii PYR-1] Length=627 Score = 600 bits (1547), Expect = 2e-169, Method: Compositional matrix adjust. Identities = 316/531 (60%), Positives = 390/531 (74%), Gaps = 27/531 (5%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 +PWPALWA+++GFFMI++D+T+V +ANP IMAQL Y V+WVTSAYLLAYAVP+LV+G Sbjct 13 DPWPALWALLIGFFMILVDATIVPVANPAIMAQLGADYDAVIWVTSAYLLAYAVPLLVSG 72 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDR+GPK +YL+GL VFT ASL CGLS GML+AARV+QGVGA LLTPQTL+ ITR Sbjct 73 RLGDRYGPKTVYLVGLAVFTAASLWCGLSDSIGMLVAARVLQGVGAALLTPQTLTVITRT 132 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FPAH RGVA+ WG A VA+L GPLAGG LVDS+GW+WIF VN+PVGV+G LA +L+P Sbjct 133 FPAHNRGVAMSVWGATAGVATLAGPLAGGVLVDSLGWQWIFIVNLPVGVLGFALAVWLVP 192 Query 196 ALPH-HPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQA 254 +LP RFD GV LSG +FLIVF LQ+GQS +W PWIWA I GI M+ F+YWQ+ Sbjct 193 SLPTARAQRFDLPGVVLSGVALFLIVFALQEGQSHDWAPWIWATIGIGIAVMAAFLYWQS 252 Query 255 RNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAP 314 N EPLIPL +F DRNFS+SNL +A I F TGM+LP+ FYAQ+VCGL+PT A+L AP Sbjct 253 VNTGEPLIPLIIFGDRNFSMSNLGVATIGFVATGMILPLMFYAQSVCGLTPTQAALLTAP 312 Query 315 TAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALG 374 A+ GVLAP VG ++DRSHP V+GFGF+++AI +TWL EM P TPIWRLV+P A+G Sbjct 313 MAVATGVLAPLVGKLVDRSHPRPVVGFGFALMAIGLTWLSIEMTPSTPIWRLVVPLTAMG 372 Query 375 VAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGG 434 VA AF+WSPL TATRNL P LAGA SGV+N RQ+G+VLGSA+MAA + S+++A++PG Sbjct 373 VAMAFIWSPLAATATRNLPPQLAGAGSGVYNTTRQVGSVLGSAAMAALLASQLSAKIPG- 431 Query 435 VDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAK 494 P + QLP F+ PFAAAMSQ+MLLPAFVALFG++AALFLV A Sbjct 432 ----EAPVPVEGQAGQLPAFLHAPFAAAMSQAMLLPAFVALFGVIAALFLVGLGDRLPAP 487 Query 495 --------EPLPESDGDAD------DDDYVEYIL-------RREPEEDCDT 524 EP+P D D + +D+YVEY + R P ++ DT Sbjct 488 PRRPQETAEPVPAFDPDDELYWADGEDEYVEYEVPWDDGAEPRRPAQEADT 538 >gi|325676130|ref|ZP_08155811.1| drug transporter [Rhodococcus equi ATCC 33707] gi|325553040|gb|EGD22721.1| drug transporter [Rhodococcus equi ATCC 33707] Length=499 Score = 549 bits (1414), Expect = 5e-154, Method: Compositional matrix adjust. Identities = 274/471 (59%), Positives = 349/471 (75%), Gaps = 0/471 (0%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 PWPALWA+ +GFFMI++DST+VA+ANP I A+L V+WVTSAYLLAYAVP+LV G Sbjct 6 RPWPALWALCLGFFMILVDSTIVAVANPVITAELNADVNAVIWVTSAYLLAYAVPLLVTG 65 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGPKN+YLIGL VFT+ASL CGLS G MLI ARV QG+GA ++TPQT++ ITRI Sbjct 66 RLGDRFGPKNMYLIGLVVFTLASLWCGLSGGVEMLIVARVFQGLGAAMMTPQTMAVITRI 125 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FP +RG A+G WG+VA VA+LVGP+ GG L+D++GW+WIFFVNVPVGV+G +LA L+P Sbjct 126 FPPDKRGTAMGLWGSVAGVATLVGPILGGVLLDNLGWQWIFFVNVPVGVVGFLLAWRLVP 185 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 +LP + H+FD GV LS G+F IVFGLQ+G S +W W +I GG+ M +FV+WQ Sbjct 186 SLPTNNHKFDMIGVALSAIGLFCIVFGLQEGNSYDWDARAWGLIAGGLVVMGVFVWWQKV 245 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N EPL+PL +F DRNFS++N+ IA + F+ TG+MLP FYAQ+V GLSPT +A+L AP Sbjct 246 NRNEPLVPLGLFKDRNFSVANVGIAAMGFSITGVMLPFMFYAQSVTGLSPTRSALLMAPM 305 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 AIV G+LAPFVG ++D++HP + G GF V A+A WL + P TP+W+++LP +G Sbjct 306 AIVTGILAPFVGRLVDKAHPRMIAGPGFLVFALATAWLATRLTPTTPVWQILLPMAIIGA 365 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 + AF+W+PL TATRNL GA SGV+N RQ+GAVLGSA+M A MTSRI AE+ Sbjct 366 SNAFIWAPLAATATRNLPSMHVGAGSGVYNTTRQVGAVLGSAAMGALMTSRITAELSTLG 425 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD 486 G+ + V QLPE VREPF+ AMSQS +LPA L G VA +F V+ Sbjct 426 VGGGAKVGEGSHVGQLPEMVREPFSTAMSQSAMLPAAALLVGFVAVMFFVN 476 >gi|240168846|ref|ZP_04747505.1| drug-transport integral membrane protein [Mycobacterium kansasii ATCC 12478] Length=491 Score = 548 bits (1411), Expect = 1e-153, Method: Compositional matrix adjust. Identities = 292/481 (61%), Positives = 347/481 (73%), Gaps = 4/481 (0%) Query 30 MIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLI 89 M +D TVV +ANP+IMA+L Y V+WVTSAY+LAY VP L+ GRLGDRFG KNLYL+ Sbjct 1 MTSVDDTVVYVANPSIMAELATDYHMVIWVTSAYVLAYTVPSLLVGRLGDRFGVKNLYLM 60 Query 90 GLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWG 149 GL VFT +SL CGLS MLIAAR VQG+GA LL QT S ITR+FP RRG A G W Sbjct 61 GLAVFTASSLWCGLSGTIEMLIAARAVQGIGAALLYTQTFSIITRVFPPERRGAAAGVWA 120 Query 150 TVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGV 209 VA SLVGPL GGALVD++GWEWIFFVN+P+GV+G+ LA +P LP H HRFD GV Sbjct 121 AVAGFGSLVGPLVGGALVDTLGWEWIFFVNIPIGVLGVALAVRFVPVLPTHAHRFDPIGV 180 Query 210 GLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFND 269 LSG G+FLIVF LQQG +A W PWIW +IV G+GF+++FVYWQ+ N REPLIPL++F D Sbjct 181 ALSGLGLFLIVFALQQGHAAGWMPWIWVMIVAGVGFLAVFVYWQSVNTREPLIPLKIFRD 240 Query 270 RNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMI 329 RNF+L ++ +A+IA MMLP FY Q VCGLSPT +A+L AP IV +L P +G I Sbjct 241 RNFALCSVGVAVIASVVAAMMLPGVFYIQTVCGLSPTRSALLMAPLPIVAALLTPIIGKI 300 Query 330 IDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTAT 389 +DR+HP V+GFGF V+AIA+TW EMAP TP+WRL LP +LG+ FVW L TAT Sbjct 301 LDRAHPRPVVGFGFFVVAIALTWFSIEMAPTTPVWRLALPIASLGMGMVFVWPALAATAT 360 Query 390 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMP---GGVDALTGPAGQDA 446 R+L HLAGASSGV+NAVR LGA LGSA MAA MTSRIAA+MP GG D L + Sbjct 361 RDLPAHLAGASSGVYNAVRALGATLGSAGMAALMTSRIAAQMPPIHGGAD-LAALGASEG 419 Query 447 TVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADD 506 T LQLPE REPF+ AMSQSMLLPAF+AL GI AALF+V G + P+ D Sbjct 420 TALQLPEAAREPFSTAMSQSMLLPAFIALTGIGAALFMVRTAGTTNTRSPIRTQATDIGT 479 Query 507 D 507 + Sbjct 480 E 480 >gi|312138486|ref|YP_004005822.1| mfs transporter [Rhodococcus equi 103S] gi|311887825|emb|CBH47137.1| putative MFS transporter [Rhodococcus equi 103S] Length=480 Score = 529 bits (1362), Expect = 6e-148, Method: Compositional matrix adjust. Identities = 265/457 (58%), Positives = 338/457 (74%), Gaps = 0/457 (0%) Query 30 MIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLI 89 MI++DST+VA+ANP I A+L V+WVTSAYLLAYAVP+LV GRLGDRFGPKN+YLI Sbjct 1 MILVDSTIVAVANPVITAELNADVNAVIWVTSAYLLAYAVPLLVTGRLGDRFGPKNMYLI 60 Query 90 GLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWG 149 GL VFT+ASL CGLS G MLI ARV QG+GA ++TPQT++ ITRIFP +RG A+G WG Sbjct 61 GLVVFTLASLWCGLSGGVEMLIVARVFQGLGAAMMTPQTMAVITRIFPPDKRGTAMGLWG 120 Query 150 TVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGV 209 +VA VA+LVGP+ GG L+D++GW+WIFFVNVPVGV+G +LA L+P+LP + H+FD GV Sbjct 121 SVAGVATLVGPILGGVLLDNLGWQWIFFVNVPVGVVGFLLAWRLVPSLPTNNHKFDMIGV 180 Query 210 GLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFND 269 LS G+F IVFGLQ+G S +W W +I GG+ M +FV+WQ N EPL+PL +F D Sbjct 181 ALSAIGLFCIVFGLQEGNSYDWDARAWGLIAGGLVVMGVFVWWQKVNRNEPLVPLGLFKD 240 Query 270 RNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMI 329 RNFS++N+ IA + F+ TG+MLP FYAQ+V GLSPT +A+L AP AIV G+LAPFVG + Sbjct 241 RNFSVANVGIAAMGFSITGVMLPFMFYAQSVTGLSPTRSALLMAPMAIVTGILAPFVGRL 300 Query 330 IDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTAT 389 +D++HP + G GF V A+A WL + P TP+W+++LP +G + AF+W+PL TAT Sbjct 301 VDKAHPRMIAGPGFLVFALATAWLATRLTPTTPVWQILLPMAIIGASNAFIWAPLAATAT 360 Query 390 RNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVL 449 RNL P GA SGV+N RQ+GAVLGSA+M A MTSRI AE+ G+ + V Sbjct 361 RNLPPMHVGAGSGVYNTTRQVGAVLGSAAMGALMTSRITAELSTLGVGGGAKVGEGSHVG 420 Query 450 QLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD 486 QLPE VREPF+ AMSQS +LPA L G VA +F V+ Sbjct 421 QLPEMVREPFSTAMSQSAMLPAAALLVGFVAVMFFVN 457 >gi|226365491|ref|YP_002783274.1| drug resistance efflux protein [Rhodococcus opacus B4] gi|226243981|dbj|BAH54329.1| drug resistance efflux protein [Rhodococcus opacus B4] Length=500 Score = 528 bits (1359), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 277/494 (57%), Positives = 356/494 (73%), Gaps = 11/494 (2%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 RNPWPALWA+++GFFMI++DST+VA+ANP IM L VVWVTSAYLLAYAVP+LV Sbjct 13 RNPWPALWALVIGFFMILVDSTIVAVANPAIMNDLHTDINKVVWVTSAYLLAYAVPLLVT 72 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDRFGPKN+YLIGL +FT ASL CGLS MLI ARV QG+GA L+TPQT++ ITR Sbjct 73 GRLGDRFGPKNIYLIGLVLFTGASLWCGLSGTITMLIVARVFQGLGAALMTPQTMAVITR 132 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 FP RRG A+G WG VA VA+LVGPLAGG LVD++GW+WIF VNVPVGVI +LA L+ Sbjct 133 TFPPDRRGTAMGLWGAVAGVATLVGPLAGGVLVDNLGWQWIFIVNVPVGVIAFVLAWRLV 192 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQA 254 PAL H H+FD GV LS GMF +VFG+Q+G S +W + A I G+ + +FV++Q+ Sbjct 193 PALETHTHKFDIPGVVLSALGMFFLVFGIQEGSSYDWSATVLASIGAGLVLLGVFVWYQS 252 Query 255 RNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAP 314 N EPL+PL +F DRNFSL+N+ I + FA T M+LP+ FY QAV GLSPT +A+L P Sbjct 253 WNRNEPLLPLALFTDRNFSLANVAITAMGFAITAMVLPLMFYTQAVRGLSPTKSALLLVP 312 Query 315 TAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALG 374 A++ GV APF+G ++DR+HP + G GF + +IA+ WL M+P IW L+LP +G Sbjct 313 MAVLTGVFAPFIGKLVDRTHPRYIAGAGFLLFSIALGWLSMVMSPDVAIWELLLPIALIG 372 Query 375 VAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGG 434 +A A +WSPL TAT NL PH AGA +GV+N RQ+GAVLGSA++ A +T+R++A+ G Sbjct 373 LANACIWSPLAATATHNLPPHQAGAGAGVYNTTRQVGAVLGSAAIGALITARLSAQ---G 429 Query 435 VDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAK 494 ++A Q+A V ++PEFV+EPFA AM+QS+ LPA V L G VA+ V F K Sbjct 430 LNA----GSQEAGVGEMPEFVKEPFATAMAQSIWLPAAVLLVGFVAS---VCFARPLRQK 482 Query 495 EPLPESDGDADDDD 508 +P S+GDA + Sbjct 483 DP-GVSEGDAASRE 495 >gi|229493801|ref|ZP_04387579.1| multidrug efflux transport protein [Rhodococcus erythropolis SK121] gi|229319300|gb|EEN85143.1| multidrug efflux transport protein [Rhodococcus erythropolis SK121] Length=494 Score = 525 bits (1353), Expect = 7e-147, Method: Compositional matrix adjust. Identities = 277/503 (56%), Positives = 355/503 (71%), Gaps = 20/503 (3%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 NPW ALWA+ +GFFMI++DST+VA+ANP IM L VVWVTSAYLLAYAVP+LV G Sbjct 6 NPWHALWALCIGFFMILVDSTIVAVANPAIMEDLGTDINKVVWVTSAYLLAYAVPLLVTG 65 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGPKNLY+IGL +FT ASL CGLS MLI AR QG+GA ++TPQT++ ITR Sbjct 66 RLGDRFGPKNLYMIGLVLFTGASLWCGLSGSVEMLIVARAFQGLGAAMMTPQTMAVITRT 125 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 F ++RG A+G WG VA VA+LVGPLAGG LVD++GWEWIF VNVPVGVI +LA L+P Sbjct 126 FAPNKRGAAMGLWGAVAGVATLVGPLAGGVLVDNLGWEWIFIVNVPVGVIAFLLAWKLVP 185 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 +LP H+FD GV LS AGMFL+VFG+Q+G S +W ++W++I G+ +++FV++Q+R Sbjct 186 SLPTSEHKFDIPGVILSAAGMFLLVFGIQEGSSYDWNGFVWSLIGAGVVLLAVFVFYQSR 245 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N EPL+PLE+F DRNFSL+N+ I + FA T M+LP+ FY QAV GLSPT +A+L P Sbjct 246 NKNEPLLPLELFKDRNFSLANVAITAMGFAITSMVLPLMFYTQAVRGLSPTQSALLLVPM 305 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 A++ G+ AP +G ++D++HP + G GF + AIA+ WL M+P IW L+LP +G Sbjct 306 AVLTGIFAPIIGKLVDKTHPRYIAGTGFLLFAIALGWLALVMSPDVAIWELLLPIGLIGF 365 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 A A +WSPL TAT NL P AGA +GV+N RQ+GAVLGSA++ A +T+R+AA+ Sbjct 366 ANACIWSPLAATATHNLPPMQAGAGAGVYNTTRQVGAVLGSAAIGALITARLAAQ----- 420 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKE 495 LTG +A V LPEFVREPF+ AMS+S+ LPA V L G VA++ Sbjct 421 -GLTG-GSSEAGVGHLPEFVREPFSTAMSESIWLPAGVLLIGFVASVCF---------AR 469 Query 496 PLPESDGDADDDDY-VEYILRRE 517 PL GDA DD V RRE Sbjct 470 PL---RGDAHDDAMAVSAEARRE 489 >gi|226307600|ref|YP_002767560.1| drug resistance efflux protein [Rhodococcus erythropolis PR4] gi|226186717|dbj|BAH34821.1| putative drug resistance efflux protein [Rhodococcus erythropolis PR4] Length=494 Score = 525 bits (1351), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 276/503 (55%), Positives = 355/503 (71%), Gaps = 20/503 (3%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 NPW ALWA+ +GFFMI++DST+VA+ANP IM L VVWVTSAYLLAYAVP+LV G Sbjct 6 NPWHALWALCIGFFMILVDSTIVAVANPAIMEDLGTDINKVVWVTSAYLLAYAVPLLVTG 65 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGPKNLY+IGL +FT ASL CGLS MLI AR QG+GA ++TPQT++ ITR Sbjct 66 RLGDRFGPKNLYMIGLVLFTGASLWCGLSGSVEMLIVARAFQGLGAAMMTPQTMAVITRT 125 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 F ++RG A+G WG VA VA+LVGPLAGG LVD++GWEWIF VNVPVGVI +LA L+P Sbjct 126 FAPNKRGAAMGLWGAVAGVATLVGPLAGGVLVDNLGWEWIFIVNVPVGVIAFLLAWKLVP 185 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 +LP H+FD GV LS AGMFL+VFG+Q+G S +W ++W++I G+ +++FV++Q+R Sbjct 186 SLPTSEHKFDIPGVILSAAGMFLLVFGIQEGSSYDWNGFVWSLIGAGVVLLAVFVFYQSR 245 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 N EPL+PLE+F DRNFSL+N+ I + FA T M+LP+ FY QAV GLSPT +A+L P Sbjct 246 NKNEPLLPLELFKDRNFSLANVAITAMGFAITSMVLPLMFYTQAVRGLSPTQSALLLVPM 305 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 A++ G+ AP +G ++D++HP + G GF + A+A+ WL M+P IW L+LP +G Sbjct 306 AVLTGIFAPIIGKLVDKTHPRYIAGTGFLLFAVALGWLALVMSPDVAIWELLLPIGLIGF 365 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 A A +WSPL TAT NL P AGA +GV+N RQ+GAVLGSA++ A +T+R+AA+ Sbjct 366 ANACIWSPLAATATHNLPPMQAGAGAGVYNTTRQVGAVLGSAAIGALITARLAAQ----- 420 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKE 495 LTG +A V LPEFVREPF+ AMS+S+ LPA V L G VA++ Sbjct 421 -GLTG-GSSEAGVGHLPEFVREPFSTAMSESIWLPAGVLLIGFVASVCF---------AR 469 Query 496 PLPESDGDADDDDY-VEYILRRE 517 PL GDA DD V RRE Sbjct 470 PL---RGDAHDDAMAVSAEARRE 489 >gi|240172791|ref|ZP_04751450.1| EmrB/QacA family drug resistance transporter [Mycobacterium kansasii ATCC 12478] Length=527 Score = 525 bits (1351), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 307/539 (57%), Positives = 371/539 (69%), Gaps = 16/539 (2%) Query 24 MMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGP 83 M++G FMI +D +V +ANP+IM L Y TV+WVTSA +LAYAV LVAGRLGDRFGP Sbjct 1 MLLGSFMIQVDFIIVVVANPSIMTDLHSDYDTVIWVTSAAVLAYAVSALVAGRLGDRFGP 60 Query 84 KNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGV 143 KN+YLIGL +FT ASL CGLS MLIAAR +QG+GA LL QTLSTITR FP RRG Sbjct 61 KNVYLIGLAIFTAASLWCGLSDSVEMLIAARAIQGIGASLLNTQTLSTITRTFPPERRGT 120 Query 144 ALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHR 203 AL WG A +A+LVGPL GG LV ++GW+ IFFVNVP+GV+GL LAA IP LP H HR Sbjct 121 ALSVWGATAGIATLVGPLLGGLLVGALGWKSIFFVNVPIGVVGLALAARWIPVLPTHTHR 180 Query 204 FDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIP 263 FDW GV LSG G L+VF LQ+GQSA W WIWA I G+GF+++FV+WQ+ N REPLIP Sbjct 181 FDWIGVALSGMGTSLVVFALQEGQSAGWGTWIWAAIGTGMGFLAVFVHWQSVNLREPLIP 240 Query 264 LEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLA 323 LE+F R+F+LS+L +A+IAF T MMLP FYAQ V GLSP +A+L AP A+ +LA Sbjct 241 LEIFRYRDFALSSLGVAMIAFVTTAMMLPAMFYAQGVLGLSPAQSALLTAPMAVTTTLLA 300 Query 324 PFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSP 383 P VG ++DR+HP V+GFGFS+++ A+TWL EM PG PIW+LVLPF ALGV A +WSP Sbjct 301 PLVGKLVDRAHPRPVIGFGFSLVSAALTWLAVEMTPGAPIWQLVLPFAALGVGMAMLWSP 360 Query 384 LTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPG-GVDALTGPA 442 L TA+RNL HLAGA SGV+N+VR LGAVLGS+ MAAFM +RIAAE P Sbjct 361 LAATASRNLPAHLAGACSGVYNSVRLLGAVLGSSGMAAFMAARIAAETPNHSGPPPPPAG 420 Query 443 GQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDG 502 G ++LP+ +REPF+ AMSQSMLLPAFVAL G+VAALF+V +GA ++ + P S Sbjct 421 GGTGIGVRLPDLMREPFSTAMSQSMLLPAFVALLGVVAALFMVG-SGAHLSSDRCPRSAT 479 Query 503 DADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGP 561 RR P D QP AA A A P T+ MP P Sbjct 480 AGKIGS------RRFP---IDVQPT-----AATAKKSPPAPNPTDSCGRTNGNTMPARP 524 >gi|183983799|ref|YP_001852090.1| drug-transport integral membrane protein [Mycobacterium marinum M] gi|183177125|gb|ACC42235.1| drug-transport integral membrane protein [Mycobacterium marinum M] Length=511 Score = 523 bits (1348), Expect = 3e-146, Method: Compositional matrix adjust. Identities = 284/489 (59%), Positives = 359/489 (74%), Gaps = 2/489 (0%) Query 4 AIRRAAGSSYFR--NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTS 61 A R A G+ R NPWPALWAM+VG+FMI+LDSTVV +ANP+IMA Y V+WVTS Sbjct 11 ARRIARGTRRARSLNPWPALWAMLVGYFMIVLDSTVVMLANPSIMADQHTSYYLVIWVTS 70 Query 62 AYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGA 121 AYLL YA P+LVAGRLGDRFGPKN+Y+IGL VFT ASL CGLS GMLI AR VQG+GA Sbjct 71 AYLLTYAAPLLVAGRLGDRFGPKNIYVIGLAVFTAASLWCGLSGSIGMLITARAVQGLGA 130 Query 122 GLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVP 181 LL PQTLS ITRIF RRGVAL W VA+LVGPLAGG LV ++GW+WIFF+NVP Sbjct 131 SLLFPQTLSIITRIFEPQRRGVALAIWTATGGVATLVGPLAGGVLVQALGWQWIFFINVP 190 Query 182 VGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVG 241 +G+ GL+LAA L+P LP H + D G LS G+FL++F LQ+GQ A W PW +++G Sbjct 191 IGLAGLVLAALLLPVLPVHRPQLDLLGAALSALGVFLVLFALQEGQHAGWAPWTSMMLIG 250 Query 242 GIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVC 301 G+G +++FVYWQ+ N +PL+PL++F+DRNFSLS++ +A +AFA T MM+P F+ Q+ Sbjct 251 GVGVIAVFVYWQSVNRGDPLVPLKIFSDRNFSLSSIGVAAVAFATTAMMVPAMFFVQSAV 310 Query 302 GLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGT 361 GLSP +A L AP ++ GV++P VG I+DR HP V+ F++LA+A+TWL EM+ T Sbjct 311 GLSPIRSAALIAPMVVMSGVVSPLVGKIVDRYHPKLVVSSAFTMLAVALTWLSIEMSLST 370 Query 362 PIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAA 421 PIWRLVLP ALGVA FVW+PL +R+L LAG +GV+ A RQ+GAVLG++ MAA Sbjct 371 PIWRLVLPITALGVAIPFVWAPLAAIGSRDLPAQLAGTGAGVYTAARQVGAVLGASGMAA 430 Query 422 FMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAA 481 FMT+RIAAEMP G D T ++LP +REPF+ AMSQSMLLPA VAL G+ A Sbjct 431 FMTARIAAEMPPSPGNSPALRGSDGTAVRLPGLLREPFSVAMSQSMLLPACVALCGVAAG 490 Query 482 LFLVDFTGA 490 LF++ F+G+ Sbjct 491 LFMLGFSGS 499 >gi|111022986|ref|YP_705958.1| multidrug efflux transport protein [Rhodococcus jostii RHA1] gi|110822516|gb|ABG97800.1| multidrug efflux transport protein [Rhodococcus jostii RHA1] Length=504 Score = 516 bits (1329), Expect = 5e-144, Method: Compositional matrix adjust. Identities = 276/494 (56%), Positives = 355/494 (72%), Gaps = 11/494 (2%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 RNPWPALWA+++GFFMI++DST+VA+ANP IM L VVWVTSAYLLAYAVP+LV Sbjct 17 RNPWPALWALVIGFFMILVDSTIVAVANPAIMNDLHTDINKVVWVTSAYLLAYAVPLLVT 76 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDRFGPKN+YLIGL +FT ASL CGLS MLI ARV QG+GA L+TPQT++ ITR Sbjct 77 GRLGDRFGPKNIYLIGLVLFTGASLWCGLSGTITMLIVARVFQGLGAALMTPQTMAVITR 136 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 FP RRG A+G WG VA VA+LVGPLAGG LVD++GWEWIF VNVPVGV+ +LA L+ Sbjct 137 TFPPDRRGTAMGLWGAVAGVATLVGPLAGGVLVDNLGWEWIFIVNVPVGVVAFVLAWRLV 196 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQA 254 P+L H H+FD GV LS GMF +VFG+Q+G S +W + A I G+ + +FV++Q+ Sbjct 197 PSLETHEHKFDIPGVVLSALGMFFLVFGIQEGSSYDWSATVLASIGAGLVLLGVFVWYQS 256 Query 255 RNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAP 314 N EPL+PL +F DRNFSL+N+ I + FA T M+LP+ FY QAV GLSPT +A+L P Sbjct 257 WNKNEPLLPLGLFKDRNFSLANVAITSMGFAITAMVLPLMFYTQAVRGLSPTRSALLLVP 316 Query 315 TAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALG 374 A++ GV APF+G ++DR+HP + G GF + +IA+ WL M+P IW L+LP +G Sbjct 317 MAVLTGVFAPFIGKLVDRTHPRYIAGAGFLLFSIALAWLSMVMSPDVAIWELLLPIGLIG 376 Query 375 VAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGG 434 +A A +WSPL TAT NL PH AGA +GV+N RQ+GAVLGSA++ A +T+R++A+ G Sbjct 377 LANACIWSPLAATATHNLPPHQAGAGAGVYNTTRQVGAVLGSAAIGALITARLSAQ---G 433 Query 435 VDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAK 494 ++A Q+A V ++PEFV+EPFA AMSQS+ LPA V L G +A+ V F K Sbjct 434 LNA----DSQEAGVGEMPEFVKEPFATAMSQSIWLPAAVLLIGFLAS---VCFARPLREK 486 Query 495 EPLPESDGDADDDD 508 +P S GDA + Sbjct 487 KP-GVSAGDAASRE 499 >gi|343928045|ref|ZP_08767510.1| putative drug resistance efflux protein [Gordonia alkanivorans NBRC 16433] gi|343762053|dbj|GAA14436.1| putative drug resistance efflux protein [Gordonia alkanivorans NBRC 16433] Length=518 Score = 515 bits (1327), Expect = 8e-144, Method: Compositional matrix adjust. Identities = 262/477 (55%), Positives = 346/477 (73%), Gaps = 5/477 (1%) Query 10 GSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAV 69 GS PW AL A+ VGFFMI++D T+VA+A P I A L VVWVTSAYLL YAV Sbjct 13 GSEVTTRPWAALMALCVGFFMILVDMTIVAVAQPRIQADLNTDVNGVVWVTSAYLLTYAV 72 Query 70 PMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTL 129 P+L+ GRLGD++GPK++Y IGL VFT+AS+ CGLS G LIAAR +QGVGA L+TPQT+ Sbjct 73 PLLITGRLGDKYGPKSMYQIGLIVFTIASVWCGLSDSIGELIAARALQGVGAALITPQTM 132 Query 130 STITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLIL 189 S ITRIFP +RG A+G WGTVA VA+LVGPL GG L D+ GWEWIFF+NVPVG+ GL+L Sbjct 133 SLITRIFPPEKRGAAMGIWGTVAGVATLVGPLLGGVLTDAFGWEWIFFINVPVGIAGLVL 192 Query 190 AAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLF 249 AA L+P + + H+FDW GVGLS G+ +VFG+Q+G+S +W W+WA+I GG+ F+ +F Sbjct 193 AAVLVPQVETNDHQFDWIGVGLSAVGLSALVFGIQEGESFDWAAWVWALIGGGLIFLGVF 252 Query 250 VYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA 309 V+WQ+R EPL+PL +F DRNF+L+ + I+ + FA + MM+P+TF+ Q V G++PT +A Sbjct 253 VWWQSRIRTEPLLPLSLFRDRNFALATVGISSMGFAVSAMMIPLTFFLQLVGGMTPTQSA 312 Query 310 VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP 369 V+ P AI+ G+LAP VG ++DR HP ++ + AIA+ WL P TP+W ++LP Sbjct 313 VVLVPMAILTGILAPIVGRVVDRVHPRAIVSTALLLNAIAIGWLGVVARPDTPVWMIILP 372 Query 370 FIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAA 429 +GVA A +W+PL TATRNL H AGA +GV+N +R +G+VLGSA + A + SR+AA Sbjct 373 LCLMGVASAGIWAPLAATATRNLPWHQAGAGAGVYNTLRVIGSVLGSAMIGALLQSRLAA 432 Query 430 EMPGGVDALTGPAGQDAT-VLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLV 485 E+P G+DA A QDA+ QLPEF+RE FA+AM QS+ LPA L G+VA F V Sbjct 433 ELP-GIDA---GAAQDASGANQLPEFLREGFASAMGQSLFLPAAALLVGVVATFFFV 485 >gi|326383546|ref|ZP_08205232.1| permease of the major facilitator superfamily protein [Gordonia neofelifaecis NRRL B-59395] gi|326197630|gb|EGD54818.1| permease of the major facilitator superfamily protein [Gordonia neofelifaecis NRRL B-59395] Length=503 Score = 512 bits (1319), Expect = 6e-143, Method: Compositional matrix adjust. Identities = 259/490 (53%), Positives = 348/490 (72%), Gaps = 15/490 (3%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLR---IGYATVV 57 MTT+ + R+PWPALWA+++GFFM+++D+T+V++ANP I L VV Sbjct 1 MTTSPAASGAGDTQRSPWPALWALVIGFFMVLVDTTIVSVANPAIKEALDPDTNNLDNVV 60 Query 58 WVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQ 117 WVTSAYLLAYAVP+L+ GRLGDRFGP+NLYLIG+ VFT++SLGCGLS+ MLIA R VQ Sbjct 61 WVTSAYLLAYAVPLLITGRLGDRFGPRNLYLIGITVFTLSSLGCGLSNTLTMLIAFRAVQ 120 Query 118 GVGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFF 177 G+GA ++TPQT++ ITR FP H+RG A+G WG+VA +A LVGPLAGG LVD GWEWIFF Sbjct 121 GLGAAMVTPQTMAVITRTFPPHQRGAAMGLWGSVAGIAMLVGPLAGGLLVDHAGWEWIFF 180 Query 178 VNVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWA 237 VNVPVG+IG A L+P L HPHRFD GV +S G+FLIVFGLQ+GQ +W W+W Sbjct 181 VNVPVGIIGFAAAWKLVPKLETHPHRFDLVGVAISTIGLFLIVFGLQEGQKYDWAAWVWV 240 Query 238 VIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYA 297 +++GG+ M+LF++ Q+R + EPL+PLE+F DRNFS+SN+ IA++ FA T M LP+ F+ Sbjct 241 MVIGGVAIMALFLWQQSRTSSEPLVPLELFRDRNFSISNIGIAVVGFAVTSMTLPMMFFI 300 Query 298 QAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEM 357 Q GLSPT +A+L P A++ G+LAP G ++DR+ P +L G + ++++ W M Sbjct 301 QVARGLSPTKSALLLIPMAVLAGILAPLAGKLLDRTDPRFLLVPGIGLYSVSLFWYASMM 360 Query 358 APGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSA 417 TPI +LP +G+A A +W PL TATRNL P AGA +G++N RQ+G+V+GSA Sbjct 361 NADTPIPMFLLPAALMGIANAGMWGPLATTATRNLPPRQAGAGAGIYNTTRQIGSVIGSA 420 Query 418 SMAAFMTSRIAAEMPG--GVDAL-TGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVA 474 ++AA M R+ A +PG G D++ TG LP+F+ PF+ AM+QSMLLPA V Sbjct 421 AIAAAMQGRLQANVPGATGTDSVGTG---------SLPDFLVAPFSTAMAQSMLLPAAVL 471 Query 475 LFGIVAALFL 484 L G+VA F+ Sbjct 472 LIGVVAVAFM 481 >gi|262201828|ref|YP_003273036.1| EmrB/QacA subfamily drug resistance transporter [Gordonia bronchialis DSM 43247] gi|262085175|gb|ACY21143.1| drug resistance transporter, EmrB/QacA subfamily [Gordonia bronchialis DSM 43247] Length=505 Score = 510 bits (1313), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 268/492 (55%), Positives = 344/492 (70%), Gaps = 16/492 (3%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 PW AL A+ VGFFMI++D T+VA+A P I A L +VWVTSAYLL YAVP+L+ G Sbjct 14 RPWVALLALCVGFFMILVDMTIVAVAQPQIQAALDTDVNGIVWVTSAYLLTYAVPLLITG 73 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGD+FGPKN+Y +GL VFT+ASL CGLSS G LIAAR +QGVGA L+TPQT++ ITRI Sbjct 74 RLGDKFGPKNVYQLGLLVFTLASLWCGLSSSIGELIAARALQGVGAALITPQTMALITRI 133 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FP +RG A+G WGTVA VA+LVGPL GG L DS GWEWIFFVN+PVG++GLILAA L+P Sbjct 134 FPPEKRGAAMGVWGTVAGVATLVGPLLGGILTDSFGWEWIFFVNIPVGIVGLILAAMLVP 193 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQAR 255 ++ H H+FDW GV LS G+ +VFG+Q+G++ +W WIW +IVGG+ M+LFVYWQ+R Sbjct 194 SVETHDHQFDWIGVVLSAIGLSALVFGIQEGETYDWAAWIWVLIVGGVLTMALFVYWQSR 253 Query 256 NAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPT 315 EPL+PL +F DRNFSLSN+ IA + FA +G+M+P+ F+ Q V G+SPT +AV+ P Sbjct 254 IQTEPLVPLSLFRDRNFSLSNIGIASMGFAISGLMIPMMFFLQLVGGMSPTQSAVMMVPM 313 Query 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375 A++ GVLAP VG I+DR HP ++ + AIA+ L P TP+W+ V+P +GV Sbjct 314 AVLTGVLAPIVGRILDRVHPRAIISSALLLNAIAVFLLGILAKPATPVWQFVIPLCLMGV 373 Query 376 AGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGV 435 A A +W+PL TATRNL AGA +GV+N R +G+VLG+A + A M +R+AAE+P GV Sbjct 374 ASAGIWAPLAATATRNLPWRQAGAGAGVYNTTRMIGSVLGAAMVGALMQTRLAAELP-GV 432 Query 436 DALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKE 495 D TV QLP F+RE FA AM QS+ LPA L G+ A +FLV Sbjct 433 DT----NEHRDTVAQLPAFIREGFADAMGQSLFLPAAALLVGVAATVFLVR--------- 479 Query 496 PLPESDGDADDD 507 P+ A DD Sbjct 480 --PKHQASATDD 489 >gi|119718568|ref|YP_925533.1| EmrB/QacA family drug resistance transporter [Nocardioides sp. JS614] gi|119539229|gb|ABL83846.1| drug resistance transporter, EmrB/QacA subfamily [Nocardioides sp. JS614] Length=493 Score = 509 bits (1311), Expect = 5e-142, Method: Compositional matrix adjust. Identities = 264/474 (56%), Positives = 338/474 (72%), Gaps = 4/474 (0%) Query 11 SSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVP 70 +S + PWPAL+A+ +GFFMI++D+T+V++A P I+ LR G VVWVTSAYLLAYAVP Sbjct 15 TSEQKEPWPALFALCIGFFMILVDTTIVSVATPAIIEDLRAGVNDVVWVTSAYLLAYAVP 74 Query 71 MLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLS 130 +L+ GRLGDRFGPK LYL GL VFT+ASL CGL+ MLIAARV+QGVGA ++TPQT++ Sbjct 75 VLITGRLGDRFGPKRLYLTGLTVFTLASLWCGLTGSIEMLIAARVLQGVGASMMTPQTMA 134 Query 131 TITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILA 190 ITRIFPAHRRG A+ WG A VA+LVGP+ GG LVD +GWEWIFF+NVPVG+IG +LA Sbjct 135 IITRIFPAHRRGSAMALWGATAGVATLVGPILGGVLVDGLGWEWIFFINVPVGLIGFVLA 194 Query 191 AYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFV 250 L+P L H HRFDW GV LSG GMFL+VFG+Q+G +W IW +I G+ + FV Sbjct 195 VRLVPRLETHAHRFDWVGVALSGVGMFLLVFGIQEGHQYDWNGVIWTLIGTGLVVLGAFV 254 Query 251 YWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAV 310 WQARN REPL+PL +F DRNF+L+N+ I+++ FA T M +P+ +AQ V GLSPT +A+ Sbjct 255 VWQARNRREPLVPLGLFADRNFTLANVAISVMGFAITAMAIPIMIWAQVVRGLSPTRSAL 314 Query 311 LFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPF 370 L P A++ LA VG + DR HP + FGF+ + ++ WL M P T IW LV Sbjct 315 LLVPMAVMTIALARNVGRLTDRVHPRQLTSFGFACIVASLVWLSVLMTPDTSIWWLVPAM 374 Query 371 IALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAE 430 + LG+ A VW+P + TATRNL LAGA SGV+NA RQ+GAVLGSA++A M +R++AE Sbjct 375 VLLGIGNACVWAPNSATATRNLPMRLAGAGSGVYNATRQVGAVLGSAAIAVLMDARLSAE 434 Query 431 MPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFL 484 G+ TG AG D + LP V + F+ AM+ SMLLPA V + G VA LF Sbjct 435 ---GLPPFTG-AGGDGGPVTLPPAVADHFSQAMATSMLLPAAVLVLGFVAVLFF 484 >gi|336119081|ref|YP_004573855.1| putative drug resistance transporter [Microlunatus phosphovorus NM-1] gi|334686867|dbj|BAK36452.1| putative drug resistance transporter [Microlunatus phosphovorus NM-1] Length=514 Score = 508 bits (1309), Expect = 8e-142, Method: Compositional matrix adjust. Identities = 262/478 (55%), Positives = 343/478 (72%), Gaps = 13/478 (2%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLR---IGYATVVWVTSAYLLAYAVPM 71 +NPWPALWA+++GFFMI++D+T+V++ANP I A L VVWVTSAYLL+YAVP+ Sbjct 16 KNPWPALWALVIGFFMILVDTTIVSVANPAIKAALDPNTNNLDNVVWVTSAYLLSYAVPL 75 Query 72 LVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLST 131 L+ GRLGDRFGPKN+YLIGL +FT+ASLGCGLS+ G L+A R VQG+GA L+TPQT++ Sbjct 76 LITGRLGDRFGPKNIYLIGLAIFTLASLGCGLSASLGALVAMRAVQGLGASLMTPQTMAV 135 Query 132 ITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAA 191 ITR FP +RRG A+G WG A VA+LVGPLAGG LVD GWEWIFFVN+PVGVIG +LA Sbjct 136 ITRTFPPNRRGAAMGLWGATAGVATLVGPLAGGLLVDGFGWEWIFFVNLPVGVIGFVLAW 195 Query 192 YLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQP-W----IWAVIVGGIGFM 246 L+P LP HPHRFD GV LS +FLIVFGLQ+G++ +W W +W +I+ G+ + Sbjct 196 ILVPKLPTHPHRFDVLGVLLSALALFLIVFGLQEGEAYDWGTIWGPITVWGMIIAGVVVL 255 Query 247 SLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPT 306 LFV+ Q+R REPL+PLE+F DRNFS+SNL IA + F T M LP+ F+ Q GL+PT Sbjct 256 VLFVWAQSRTKREPLVPLELFGDRNFSISNLAIATVGFTVTSMSLPLMFFIQLAIGLTPT 315 Query 307 HTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRL 366 A+L P A++ GVLAPF G ++DR+ P +L G + ++++ W M P TP+W Sbjct 316 RAALLMIPMAVISGVLAPFAGRLLDRTDPRFLLVPGLLLTSLSLFWYAWLMKPDTPVWMF 375 Query 367 VLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSR 426 +LP +G+ A +W PL ATRNL P AGA +G++N R +G+V+GSA++AAFM SR Sbjct 376 LLPSALMGLGNAGMWGPLATIATRNLPPRQAGAGAGIYNTTRTMGSVIGSAAIAAFMQSR 435 Query 427 IAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFL 484 + A +PG + +G GQ A LP FV + F+ AMSQ++LLPA V L G+VA LFL Sbjct 436 LVANLPGAAEH-SGGFGQGA----LPAFVVDGFSTAMSQAVLLPACVLLIGVVAVLFL 488 >gi|163841049|ref|YP_001625454.1| EmrB/QacA family drug resistance transporter [Renibacterium salmoninarum ATCC 33209] gi|162954525|gb|ABY24040.1| drug resistance transporter EmrB/QacA subfamily [Renibacterium salmoninarum ATCC 33209] Length=493 Score = 496 bits (1277), Expect = 4e-138, Method: Compositional matrix adjust. Identities = 256/491 (53%), Positives = 334/491 (69%), Gaps = 10/491 (2%) Query 18 WPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRL 77 WPALW++++GFFMI++DST+V +A P+IM VWVT AYLLAY VP+L+ GRL Sbjct 8 WPALWSLVIGFFMILVDSTIVTVAMPSIMKSFDADINQAVWVTRAYLLAYVVPLLITGRL 67 Query 78 GDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFP 137 GDRFGPKN+YLIGL VFT++S CGLS+ MLI ARVVQG+GA L+TPQT++ ITR+FP Sbjct 68 GDRFGPKNIYLIGLVVFTLSSAWCGLSNSIEMLILARVVQGLGAALMTPQTMAVITRVFP 127 Query 138 AHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPAL 197 RRG A+G WG+VA VA+LVGP+ GG LVD+ GWEWIF++NVPVGVIG I AA L+P L Sbjct 128 TERRGSAMGLWGSVAGVATLVGPILGGVLVDAAGWEWIFYINVPVGVIGFIFAARLVPTL 187 Query 198 PHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPW-----IWAVIVGGIGFMSLFVYW 252 P HRFDW GV LSG G+F IVFG+Q+ +S NW IW++I+ GI M LFV W Sbjct 188 PTTAHRFDWLGVVLSGLGLFCIVFGIQEAESYNWGKITGPIPIWSLIITGIVLMVLFVIW 247 Query 253 QARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLF 312 Q N EPL+PL +F DRNFSL+NL I+ F T M+LP+ YAQ V L+PT A+L Sbjct 248 QRLNRAEPLLPLVLFKDRNFSLANLAISATGFTITSMVLPLMLYAQNVRTLTPTQAALLL 307 Query 313 APTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIA 372 P A++ G LAP VG ++++ P GF++L++A+ W+ + PIW L+ P Sbjct 308 VPMALISGGLAPVVGKLLNKVDPRYFAIGGFAILSVALFWMGSILTADVPIWLLLFPIAL 367 Query 373 LGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMP 432 G A A +W+P+++TATRNL P LAGA SGVFN RQ+GAVLGSA++AA M +R+ +P Sbjct 368 FGFANAGIWAPVSMTATRNLDPRLAGAGSGVFNTTRQIGAVLGSAAIAAVMQARLNENLP 427 Query 433 GGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAV 492 A LPEF+R F+ AM QSM +PA V L G++AA+F V + Sbjct 428 HAPAGAA-----PAGEGPLPEFLRAGFSTAMGQSMFVPAAVILVGVLAAIFFVKPKKTSQ 482 Query 493 AKEPLPESDGD 503 K+ +P G+ Sbjct 483 KKDEVPAFAGE 493 >gi|116671551|ref|YP_832484.1| EmrB/QacA family drug resistance transporter [Arthrobacter sp. FB24] gi|116611660|gb|ABK04384.1| drug resistance transporter, EmrB/QacA subfamily [Arthrobacter sp. FB24] Length=512 Score = 494 bits (1273), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 254/478 (54%), Positives = 330/478 (70%), Gaps = 6/478 (1%) Query 12 SYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPM 71 + PWPALW++++GFFMI++D+T+V++ANP IM L +V+WVTSAYLLAYAVP+ Sbjct 2 EHVARPWPALWSLVIGFFMILIDTTIVSVANPRIMEGLNADINSVIWVTSAYLLAYAVPL 61 Query 72 LVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLST 131 L+ GRLGDRFGPK LYL GL VFT+ASL CGLS LI ARVVQG GA ++TPQT++ Sbjct 62 LITGRLGDRFGPKRLYLTGLVVFTLASLWCGLSGDVQTLILARVVQGFGAAIMTPQTMAV 121 Query 132 ITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAA 191 ITRIFP RRG A+G WG A VA+LVGP+ GG LVD +GWEWIFF+NVPVG++G ILA Sbjct 122 ITRIFPPDRRGAAMGIWGATAGVATLVGPILGGVLVDGLGWEWIFFINVPVGIVGFILAQ 181 Query 192 YLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQP-----WIWAVIVGGIGFM 246 +P L HPH+FD GV LS G+FL+VFG+Q+G++ NW +W++I+ G+ + Sbjct 182 RFVPTLSTHPHKFDIPGVLLSAVGLFLLVFGIQEGETYNWGTITGPVTVWSLIIAGLVVL 241 Query 247 SLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPT 306 FV WQ N EPL+PL +F DRNFSL+N+ I + F T LP+ FY Q V GL+PT Sbjct 242 VGFVLWQRFNKGEPLLPLSLFKDRNFSLANIGITTVGFTVTAFSLPLIFYYQVVRGLTPT 301 Query 307 HTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRL 366 +A++ P A++ G LAP VG IIDR +P + G ++++A+ W M P TPIW Sbjct 302 QSALMMVPMALISGGLAPVVGRIIDRVNPKYITAAGLVLMSVALFWNSSLMHPDTPIWLF 361 Query 367 VLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSR 426 +LP LG A A +W+PL+ TATRNL P AGA SGV+N RQ+GAVLGSA++A + +R Sbjct 362 LLPSAVLGFANAGIWAPLSSTATRNLPPRQAGAGSGVYNTTRQIGAVLGSAAIAVLIQAR 421 Query 427 IAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFL 484 +AAE+P D +G A A LPE + E F+ AM QS+LLPA V L G ALF Sbjct 422 LAAELPAAPDG-SGEASPMAFGGTLPEALHEGFSTAMGQSILLPAAVILLGAAVALFF 478 >gi|331694707|ref|YP_004330946.1| EmrB/QacA subfamily drug resistance transporter [Pseudonocardia dioxanivorans CB1190] gi|326949396|gb|AEA23093.1| drug resistance transporter, EmrB/QacA subfamily [Pseudonocardia dioxanivorans CB1190] Length=508 Score = 492 bits (1266), Expect = 8e-137, Method: Compositional matrix adjust. Identities = 258/470 (55%), Positives = 328/470 (70%), Gaps = 9/470 (1%) Query 16 NPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAG 75 +PWPALWAM+VGFFMI++DST+V++A P I L G VVWVTSAYLLAYAVP+L+ G Sbjct 17 SPWPALWAMVVGFFMILVDSTIVSVATPAIQESLGAGVDAVVWVTSAYLLAYAVPLLITG 76 Query 76 RLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRI 135 RLGDRFGP +YL+GL +FT+ASL CGL+ G L+AARVVQG+GA L+TPQT++ ITR Sbjct 77 RLGDRFGPGRVYLVGLTIFTLASLWCGLTHSIGGLVAARVVQGLGASLMTPQTMAVITRT 136 Query 136 FPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP 195 FPA RG A+ WG VA VA+LVGP+ GG LVD +GWEWIFF+NVPVGV+ +LA L+P Sbjct 137 FPAESRGRAMSLWGAVAGVATLVGPILGGVLVDGLGWEWIFFINVPVGVVAFVLAVRLVP 196 Query 196 ALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPW-----IWAVIVGGIGFMSLFV 250 AL H HRFD GV LS GMFL+VFG+Q+GQ+ +W +W++I G+ M +F+ Sbjct 197 ALETHVHRFDLLGVALSAVGMFLLVFGIQEGQTYDWGTIAGPISVWSLIGAGVVVMGVFL 256 Query 251 YWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAV 310 +WQARN EPL+ L +F DRNFSL+N+ I + FA T M P+ FYAQ V GLSPT +A+ Sbjct 257 WWQARNRGEPLVNLALFRDRNFSLANVAITTVGFAITAMAFPLMFYAQGVMGLSPTRSAL 316 Query 311 LFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPF 370 LF P A++ G LAP+VG I D HP + GFG + A+ W+ + PG +W L+LP Sbjct 317 LFVPMAVLSGGLAPWVGRITDTVHPRWIAGFGMLCFSAALFWIGAILRPGLAVWELLLPI 376 Query 371 IALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAE 430 LGVA FVW+P+ TATRNL AG+ +G++N RQ+GAVLGSA++A M SRIAA Sbjct 377 ALLGVANGFVWAPIATTATRNLPMSSAGSGAGIYNTTRQVGAVLGSAAIATLMASRIAAN 436 Query 431 MPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 +P A A V LP F+ FA+AM Q+M LPA V L G VA Sbjct 437 LPAAGAAGG----GGADVATLPPFLHAGFASAMGQAMYLPAAVLLVGFVA 482 >gi|326382060|ref|ZP_08203753.1| EmrB/QacA subfamily drug resistance transporter [Gordonia neofelifaecis NRRL B-59395] gi|326199486|gb|EGD56667.1| EmrB/QacA subfamily drug resistance transporter [Gordonia neofelifaecis NRRL B-59395] Length=508 Score = 491 bits (1263), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 261/490 (54%), Positives = 334/490 (69%), Gaps = 6/490 (1%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MT+ + A S PW AL A+ +GFFMI++D T+VA+A P IM L +VWVT Sbjct 1 MTSTPQTPAFKSVTDRPWAALMALCLGFFMILVDMTIVAVAQPQIMEALDADVNGIVWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLL YAVP+LVAGRLGD+ GPK +Y GL +FT AS+ CGLS G LIAAR VQG+G Sbjct 61 SAYLLTYAVPLLVAGRLGDKIGPKRVYQAGLLLFTAASVWCGLSGSIGELIAARSVQGLG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 A L+TPQT++ ITRIFP RRG A+G WGTVA VA+LVGPL GG L DS GWEWIFFVN+ Sbjct 121 AALITPQTMALITRIFPPERRGAAMGVWGTVAGVATLVGPLLGGILTDSFGWEWIFFVNL 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVG+ GL+LA L+P + H H+FDW GV LS G+ +VFG+Q+G+S +W WIWA+I Sbjct 181 PVGLAGLVLAQVLVPNVETHDHKFDWIGVALSAVGLSALVFGIQEGESYDWAGWIWALIG 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 G M LF W++R EPL+PL +F DRNFS+SN+ IA + FA +G M+P+ F+ Q V Sbjct 241 SGAVVMGLFFLWESRTKGEPLVPLSLFRDRNFSVSNVGIATMGFAVSGSMIPIMFFLQLV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 G++P +A++ P A++ G+ AP VG I+DR HP V+ G A+A W P Sbjct 301 GGMTPLRSALVLVPMAVLTGIFAPIVGRILDRVHPRNVVALGLFGYAVASFWAGMVFRPE 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 TP+W LV P + +G++ A VW+PL TATRNL H AGA +GV+N R +G+V+GSA + Sbjct 361 TPVWMLVAPTLLMGLSSAGVWAPLAATATRNLPWHQAGAGAGVYNTTRVIGSVIGSAGIG 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 A M SR+AA +P GVD A +V QLPEF+RE FA AM QS+ L A V L G +A Sbjct 421 ALMMSRLAANLP-GVDT----ASHSGSVQQLPEFLREGFARAMGQSIYLGAAVLLIGAIA 475 Query 481 ALFLVDFTGA 490 LFLV TGA Sbjct 476 TLFLVR-TGA 484 >gi|296138687|ref|YP_003645930.1| EmrB/QacA subfamily drug resistance transporter [Tsukamurella paurometabola DSM 20162] gi|296026821|gb|ADG77591.1| drug resistance transporter, EmrB/QacA subfamily [Tsukamurella paurometabola DSM 20162] Length=511 Score = 488 bits (1255), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 265/501 (53%), Positives = 343/501 (69%), Gaps = 26/501 (5%) Query 1 MTTAIRRAAGSSYFRN--PWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVW 58 MTT R G + PWPALWAM++GFFMI++DST+V++A +IM L +VVW Sbjct 1 MTTTDDRPVGGGLPEDYRPWPALWAMVIGFFMILVDSTIVSVATDSIMVGLGTDLNSVVW 60 Query 59 VTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQG 118 VTSAYLLAY VP+LVAGRLGD +GPKNLYLIGL +FT AS CGLS AGMLIAARVVQG Sbjct 61 VTSAYLLAYVVPLLVAGRLGDMYGPKNLYLIGLVIFTAASAWCGLSGTAGMLIAARVVQG 120 Query 119 VGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFV 178 GA L+TPQT++ ITR FPA +RG A+ WG+VA VA LVGPLAGG LVD +GWEW+FFV Sbjct 121 FGAALMTPQTMAVITRTFPADKRGSAMALWGSVAGVAILVGPLAGGVLVDRLGWEWVFFV 180 Query 179 NVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQP-W--- 234 NVPVGVI +LA L+P+LP H HRFD G+ LS AG+FL+ FGLQ+GQ +W W Sbjct 181 NVPVGVIAFLLAVRLVPSLPTHKHRFDIPGIVLSAAGLFLLTFGLQEGQKYDWGTIWHLG 240 Query 235 -----IWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGM 289 +W +I+ G+ +++FV+WQ R A EPL+ L +F DRNFSL+N+ IA + F+ TGM Sbjct 241 PVPIGVWTLIIAGLVLLAVFVWWQGR-APEPLMSLTLFKDRNFSLANVAIATMGFSVTGM 299 Query 290 MLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIA 349 +P+ +AQ GL+PT +A+L P A++ G LAP G +ID+ HP + GFGF+ +IA Sbjct 300 SIPLMLFAQKSMGLTPTRSALLLIPLAVISGGLAPLSGKLIDQVHPRYLAGFGFAANSIA 359 Query 350 MTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQ 409 + WL +P TP+ ++ P +GV AF+W PL TA RNL LAGA SGV+N RQ Sbjct 360 LFWLGAVASPTTPVVGILAPIALMGVGNAFIWGPLATTANRNLPLALAGAGSGVYNMTRQ 419 Query 410 LGAVLGSASMAAFMTSRIAAEM-----PGGV---DALTGPAGQDATVLQLPEFVREPFAA 461 +GAVLGSAS+ M ++I A++ PG DA++G G LP+F++ PFA Sbjct 420 VGAVLGSASVGVLMQNQIQAKLTPVFPPGQAPSQDAISGSVG------PLPDFLKGPFAD 473 Query 462 AMSQSMLLPAFVALFGIVAAL 482 AM S+ LPA +FG +A L Sbjct 474 AMGNSIYLPATALIFGFIAVL 494 >gi|84497705|ref|ZP_00996527.1| albicidin efflux pump [Janibacter sp. HTCC2649] gi|84382593|gb|EAP98475.1| albicidin efflux pump [Janibacter sp. HTCC2649] Length=494 Score = 486 bits (1252), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 253/475 (54%), Positives = 331/475 (70%), Gaps = 9/475 (1%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 R+PWPALWAM++GFFMI++D+T+V++A P IM L VVWVTSAYLLAYAVP+L+ Sbjct 17 RSPWPALWAMVLGFFMILVDTTIVSVATPAIMEGLDTDVNGVVWVTSAYLLAYAVPLLIT 76 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDRFGPKNLYLIGL VFT+ASL CGL+ G L+AAR+VQG+GA +LTPQT++ ITR Sbjct 77 GRLGDRFGPKNLYLIGLAVFTLASLWCGLTDSIGGLVAARIVQGLGASMLTPQTMAVITR 136 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 FPA RG A+ WG A VA LVGP+ GG L D GWEWIFF+NVPVG++GL+LA L+ Sbjct 137 TFPAASRGSAMALWGATAGVAILVGPVLGGVLTDGPGWEWIFFINVPVGIVGLVLAWRLV 196 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV-----GGIGFMSLF 249 P+L H H FDW GV LS GMFL+VFG+Q+G++ +W + V G+ ++ F Sbjct 197 PSLETHSHSFDWLGVALSAVGMFLLVFGVQEGETYDWGTISGVISVPLLIGAGLIMLAAF 256 Query 250 VYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA 309 ++WQ RN EPL+PL +F DRNFSL+N+ I I FA T M P+ +AQ V G SPT A Sbjct 257 LWWQRRNTSEPLLPLGLFVDRNFSLANVAITTIGFAFTAMGFPLMLFAQVVLGFSPTRAA 316 Query 310 VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP 369 +L P AIV LAP VG + DR HP ++GFG + ++++ WL M+P W+L+LP Sbjct 317 LLLVPMAIVSIALAPVVGKLTDRMHPRQLVGFGITTSSVSLFWLSRVMSPDIATWQLLLP 376 Query 370 FIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAA 429 +GV A +W+PL TATRNL AGA +GV+N RQ+GAV GSA++AA M +R+AA Sbjct 377 MTLMGVGSACMWAPLGATATRNLPLRSAGAGAGVYNTTRQVGAVFGSAAIAALMENRLAA 436 Query 430 EMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFL 484 +PG + G +A +LP + + FA AMSQ+++LPA V L G+VAA+ L Sbjct 437 HLPG----MPAGGGLEAAGTKLPPQLADGFAQAMSQAVVLPAAVLLIGVVAAVLL 487 >gi|220913462|ref|YP_002488771.1| EmrB/QacA subfamily drug resistance transporter [Arthrobacter chlorophenolicus A6] gi|219860340|gb|ACL40682.1| drug resistance transporter, EmrB/QacA subfamily [Arthrobacter chlorophenolicus A6] Length=509 Score = 484 bits (1245), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 263/503 (53%), Positives = 343/503 (69%), Gaps = 9/503 (1%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 PW ALW++++GFFMI++DST+V++ANP IM L +V+WVTSAYLLAYAVP+L+ Sbjct 5 EKPWAALWSLVIGFFMILIDSTIVSVANPRIMEGLGADINSVIWVTSAYLLAYAVPLLIT 64 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDRFGPK LYL+GL VFT+ASL CGL+ LIAARV+QG+GA ++TPQT++ ITR Sbjct 65 GRLGDRFGPKKLYLLGLVVFTLASLWCGLAQDVETLIAARVLQGLGAAVMTPQTMAVITR 124 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 IFP RRG A+ WG A +A+LVGP+ GG LVDS+GWEWIFF+NVP+GV+G ILA + Sbjct 125 IFPPDRRGAAMAIWGATAGMATLVGPILGGVLVDSLGWEWIFFINVPIGVVGFILAVRNV 184 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPW-----IWAVIVGGIGFMSLF 249 PAL HPHRFD GV LS G+FL+VFG+Q+G++ NW +W++I+ GI ++ F Sbjct 185 PALRTHPHRFDIPGVLLSAVGVFLLVFGIQEGETYNWGTITGPISVWSLIIAGIIVLAGF 244 Query 250 VYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA 309 V WQ N EPL+PL +F DRNFSL+NL I ++ F T LP+ FY Q V GL+PT +A Sbjct 245 VTWQRFNKGEPLLPLGLFRDRNFSLANLGITMVGFTVTSFGLPLIFYYQMVRGLTPTQSA 304 Query 310 VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP 369 +L P A++ G +AP VG I+DR +P + G +++A+A+ W M P TPIW +LP Sbjct 305 LLMVPMALISGGMAPVVGKIVDRVNPKYLATAGLTLMAVALVWNGLLMQPDTPIWLFLLP 364 Query 370 FIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAA 429 LG A A +W+PL+ TATRNL P AGA SGV+N RQ GAVLGSA++A + SR+AA Sbjct 365 SAVLGFANAGIWAPLSTTATRNLPPRQAGAGSGVYNTTRQFGAVLGSAAIAVLIQSRLAA 424 Query 430 EM-PGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVD-- 486 E+ G G A LPEF+ F+ AM+QS+LLPA V L G V LF Sbjct 425 ELPAGPGGQAGGAGEGMAMGGSLPEFLHAGFSTAMAQSILLPAAVVLAGAVVVLFFAKPK 484 Query 487 -FTGAAVAKEPLPESDGDADDDD 508 G A+EP+P + DA D Sbjct 485 PVQGWGSAEEPVPSAKVDAGLDS 507 >gi|50955766|ref|YP_063054.1| albicidin efflux pump [Leifsonia xyli subsp. xyli str. CTCB07] gi|50952248|gb|AAT89949.1| albicidin efflux pump [Leifsonia xyli subsp. xyli str. CTCB07] Length=512 Score = 482 bits (1240), Expect = 8e-134, Method: Compositional matrix adjust. Identities = 261/484 (54%), Positives = 338/484 (70%), Gaps = 19/484 (3%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIG--YATVVWVTSAYLLAYAVPML 72 R PWPALWA+++GFFMI++D+T+V++ANP+IM L +G Y V+WVTSAYLLAYAVP+L Sbjct 5 RKPWPALWALVIGFFMILIDTTIVSVANPSIMKGLNLGANYNAVIWVTSAYLLAYAVPLL 64 Query 73 VAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSS-----GAGMLIAARVVQGVGAGLLTPQ 127 + GRLGDRFGPKN+YLIGL VFT+AS CG S G GMLI ARVVQG+GA L+TPQ Sbjct 65 ITGRLGDRFGPKNIYLIGLVVFTLASAWCGFSGDMPGGGIGMLITARVVQGLGAALMTPQ 124 Query 128 TLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGL 187 T++ ITRIF RRG A+G WG VA VA+LVGPL GG LVDS+GWEWIFF+NVPVG + Sbjct 125 TMAVITRIFLPDRRGAAMGLWGAVAGVATLVGPLLGGVLVDSLGWEWIFFINVPVGFVAF 184 Query 188 ILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPW-----IWAVIVGG 242 +LA L+P LP H HRFD GV LS GMFL+VFG+Q+G + +W +W +IV G Sbjct 185 VLAVRLVPELPTHSHRFDILGVVLSAVGMFLLVFGIQEGGTYDWGVIGGPVSVWGLIVAG 244 Query 243 IGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCG 302 I + FV WQA N +EPL+PL +F DRNFSLSN I + FA T M LP+ FY Q V G Sbjct 245 IVVLIGFVIWQALNKKEPLLPLTLFKDRNFSLSNGAITAVGFAVTCMALPLVFYFQTVRG 304 Query 303 LSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTP 362 L+PT +A++ APTA+ GVLAP VG +ID+ +P+ + G + +A+ ++P Sbjct 305 LTPTQSALMLAPTAVFSGVLAPVVGRLIDKVNPVFIAAPGLVLFGLALFLYSQMLSPDAN 364 Query 363 IWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAF 422 I L++P LG+A + VW P++ T TRNL AGA SGVFN RQ+GAVLGSAS+AA Sbjct 365 IGLLLIPGALLGIAMSGVWGPISATTTRNLPLSQAGAGSGVFNTTRQVGAVLGSASIAAL 424 Query 423 MTSRIAAEMPGGVDALTGPAGQDATV-LQLPEFVREPFAAAMSQSMLLPAFVALFGIVAA 481 ++ R++ ++P G +G AT +LP F+ F AMS+S+LLPA VA+ G A Sbjct 425 ISGRLSVDLP---KLPGGASGNGATTGTELPAFLHAGFTQAMSESLLLPAAVAVLG---A 478 Query 482 LFLV 485 LF++ Sbjct 479 LFVI 482 >gi|183981892|ref|YP_001850183.1| drug-transport integral membrane protein [Mycobacterium marinum M] gi|183175218|gb|ACC40328.1| drug-transport integral membrane protein [Mycobacterium marinum M] Length=500 Score = 481 bits (1239), Expect = 1e-133, Method: Compositional matrix adjust. Identities = 283/469 (61%), Positives = 339/469 (73%), Gaps = 2/469 (0%) Query 21 LWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDR 80 LWA+ +G FM +D TVV +ANP+IMA L Y V+WVTS Y+LAY VP LVAGRLGDR Sbjct 21 LWAIAIGIFMTSVDDTVVYVANPSIMAGLNTSYHMVIWVTSGYVLAYTVPSLVAGRLGDR 80 Query 81 FGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHR 140 FG KNLYL GL VFTV+SL CG+S +LIAARV QG+GA LL QT + +TR FP R Sbjct 81 FGVKNLYLAGLAVFTVSSLWCGVSGTIEILIAARVAQGIGAALLYTQTFTIVTRAFPPER 140 Query 141 RGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHH 200 RG A W A +LVGPL GGALVD++GW+WIFFVN+PVG++GL+LA +PALP H Sbjct 141 RGAAATVWAAAAGFGNLVGPLLGGALVDTLGWQWIFFVNIPVGIVGLVLAVRFVPALPTH 200 Query 201 PHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREP 260 RFD GVGLSG G+ LIVFGLQQG +A W PWIWA+I G+GF+++FVYWQ+ N EP Sbjct 201 ARRFDLIGVGLSGLGLLLIVFGLQQGHAAGWSPWIWAMIAVGVGFVTVFVYWQSVNTSEP 260 Query 261 LIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGG 320 LIPL +F DRNF+L + +A+IAF MMLP FY Q V GLSPT TA+L AP IV G Sbjct 261 LIPLRIFGDRNFALCSFGVAVIAFVAAAMMLPGVFYMQTVRGLSPTRTALLMAPLPIVVG 320 Query 321 VLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFV 380 +L PF+G I+DR+HP V GFGFSV+AI++ W EMAP TP+WRL +P LGV F Sbjct 321 LLTPFIGKILDRAHPRAVAGFGFSVVAISLIWFSIEMAPATPVWRLAVPIAFLGVGMVFA 380 Query 381 WSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVD--AL 438 W LTVTATR+L L GASSGV+NA R LGA LGSA MAA MTSRIAA+ P D Sbjct 381 WPVLTVTATRDLPAELVGASSGVYNAARALGATLGSAGMAALMTSRIAAQAPAIHDDAHT 440 Query 439 TGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDF 487 + A + LQLPEF REPF+A+MSQS+LLPA +AL G+ AALF+ D Sbjct 441 SAAAATEGVALQLPEFAREPFSASMSQSLLLPALIALLGVGAALFMSDL 489 >gi|183983949|ref|YP_001852240.1| drug-transport integral membrane protein [Mycobacterium marinum M] gi|183177275|gb|ACC42385.1| drug-transport integral membrane protein [Mycobacterium marinum M] Length=499 Score = 480 bits (1235), Expect = 3e-133, Method: Compositional matrix adjust. Identities = 269/496 (55%), Positives = 339/496 (69%), Gaps = 10/496 (2%) Query 1 MTTAIRRAAGSSY--------FRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIG 52 ++ A+RRA ++ + PW ALWA+MVG+FMI D TVV +ANP+I L Sbjct 4 LSDAVRRARSTTSALLGSPADSQKPWYALWALMVGWFMIGFDITVVMVANPSIKVSLDAD 63 Query 53 YATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIA 112 Y+ V+WVTSAYLLA VP+L GRLGDRFGPK +YLIGL +FTV SL C LS G MLI Sbjct 64 YSKVIWVTSAYLLASTVPLLTTGRLGDRFGPKKMYLIGLTIFTVGSLWCSLSQGVTMLIG 123 Query 113 ARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGW 172 ARVVQG+GA LL PQ L TIT+IFP RRG+ALG + +A LVGP AGGALV + W Sbjct 124 ARVVQGLGASLLAPQLLLTITQIFPPQRRGMALGISSAIGGLALLVGPFAGGALVSGLSW 183 Query 173 EWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQ 232 +WIF +NVP+G+ GLILAA+ IPA+P +FD G+GLSG GMFL+VF LQQGQSA+W Sbjct 184 QWIFLINVPIGICGLILAAWFIPAVPTQARQFDLLGLGLSGIGMFLVVFALQQGQSASWA 243 Query 233 PWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLP 292 PWIW +++ G+ M+LFVYWQA ++ EPLIPL +F +R F+ S+L I + + LP Sbjct 244 PWIWFMLLSGVVLMALFVYWQAISSGEPLIPLRIFGNREFAWSSLGIVVYGLLIMALGLP 303 Query 293 VTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTW 352 FYAQ VCGLSP TA+L +P I ++ P VG I+DR++ VLG F+ +A+A+ W Sbjct 304 TIFYAQMVCGLSPMGTALLCSPMPIAAFLVTPIVGKIVDRANQRPVLGCAFATVAVALAW 363 Query 353 LLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGA 412 L EM P T I L++P I LG+ AF+ LT TATR L P LAGA SGV+N LG Sbjct 364 LSFEMVPDTSISHLIMPTIVLGLGLAFIRPALTATATRKLAPQLAGAGSGVYNTAGSLGQ 423 Query 413 VLGSASMAAFMTSRIAAEMPGGVDA--LTGPAGQDATVLQLPEFVREPFAAAMSQSMLLP 470 +LGSASMAAF+ SR AAEMP D+ L+ + T +QL E +REPFAA MSQSMLL Sbjct 424 LLGSASMAAFIASRTAAEMPTPSDSAQLSALREAEKTGVQLVESLREPFAAVMSQSMLLL 483 Query 471 AFVALFGIVAALFLVD 486 A +AL G+ A F+ D Sbjct 484 ALIALIGMATAFFIAD 499 >gi|317125848|ref|YP_004099960.1| drug resistance transporter EmrB/QacA subfamily [Intrasporangium calvum DSM 43043] gi|315589936|gb|ADU49233.1| drug resistance transporter, EmrB/QacA subfamily [Intrasporangium calvum DSM 43043] Length=523 Score = 478 bits (1229), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 255/475 (54%), Positives = 325/475 (69%), Gaps = 8/475 (1%) Query 15 RNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVA 74 R+PWPALWAM++GFFMI++DST+V++A P IM VVWVTSAYLLAYAVP+L+ Sbjct 44 RSPWPALWAMVLGFFMILVDSTIVSVATPAIMVAFDANVNGVVWVTSAYLLAYAVPLLIT 103 Query 75 GRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITR 134 GRLGDR+GPK LYLIGL VFT+ASL CGL+ G L+ ARVVQG+GA +LTPQT++ ITR Sbjct 104 GRLGDRYGPKRLYLIGLTVFTLASLWCGLTDTIGALVVARVVQGIGASMLTPQTMAVITR 163 Query 135 IFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLI 194 FPA RG A+ WG A VA LVGP+ GG L D GWEWIFFVNVPVG++GL+LA L+ Sbjct 164 TFPAASRGQAMALWGATAGVAMLVGPILGGLLTDGPGWEWIFFVNVPVGIVGLVLAIRLV 223 Query 195 PALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPW-----IWAVIVGGIGFMSLF 249 P L H H FDW GV LS GMFLIVF +Q+G++ +W I A+I+ G+ + +F Sbjct 224 PRLETHTHSFDWLGVVLSAVGMFLIVFAIQEGETYDWGTITGPVSIPALIILGLIVIGVF 283 Query 250 VYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTA 309 ++WQ RN+REPL+PL +F DRNFSL+N I+ + + T M P+ YAQ V GLSPT A Sbjct 284 LWWQRRNSREPLLPLGLFRDRNFSLANAGISAVGCSITAMAFPLMLYAQGVRGLSPTGAA 343 Query 310 VLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLP 369 +L AP A++ G LAP G + DR HP + FG A A+ WL M P T W+L+LP Sbjct 344 LLLAPMAVISGGLAPVAGRLTDRLHPRSLASFGVVTTAGAIFWLASVMRPDTETWQLLLP 403 Query 370 FIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAA 429 +GV F+W+PL+ TATRNL AGA SGV+N RQ+GAVLGSA++A M +R+A Sbjct 404 MSLMGVGSPFLWAPLSATATRNLPMSAAGAGSGVYNTTRQVGAVLGSAAIAVLMQARLAT 463 Query 430 EMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFL 484 +PG T A +P + + FAAAM++SM+LPA V L G+VA LF Sbjct 464 NLPG---IPTDGAAIRQGGGTMPPAIADGFAAAMAESMVLPAAVLLAGVVAVLFF 515 >gi|326331870|ref|ZP_08198157.1| drug transporter [Nocardioidaceae bacterium Broad-1] gi|325950367|gb|EGD42420.1| drug transporter [Nocardioidaceae bacterium Broad-1] Length=490 Score = 477 bits (1228), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 253/484 (53%), Positives = 320/484 (67%), Gaps = 5/484 (1%) Query 1 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVT 60 MT A + +PW +L A+ +GFFMI++D T+V +A P IM L V+WVT Sbjct 1 MTETTASQAPGTTVEHPWRSLAALCIGFFMILVDMTIVTVATPDIMRDLEASTNDVLWVT 60 Query 61 SAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVG 120 SAYLL YAVP+L+ GRLGDRFGPK LYL GL +FT+ASL CGL+ MLI AR VQGVG Sbjct 61 SAYLLTYAVPVLIMGRLGDRFGPKWLYLGGLAIFTLASLWCGLADDITMLIIARAVQGVG 120 Query 121 AGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNV 180 A ++TPQT++ ITRIFPA RRG A+ WG A +A+LVGP+ GG LVD GWEWIFF+N+ Sbjct 121 ASMMTPQTMAVITRIFPADRRGAAMALWGATAGIATLVGPILGGVLVDLGGWEWIFFINI 180 Query 181 PVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIV 240 PVGV+ L+L L+P LP HPH FDW GV LSG GMF +VFGLQ G+ W IWA++V Sbjct 181 PVGVVALVLNWRLVPLLPTHPHVFDWLGVALSGIGMFGLVFGLQDGEQRGWDGLIWALVV 240 Query 241 GGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAV 300 GG+ + LFV W+ARN +EPL+PL +F DRNFS++N+ I + A T M P+ YAQ V Sbjct 241 GGVAVLGLFVLWEARNKQEPLLPLGLFGDRNFSVANIAITCMGMAATTMGFPLMLYAQIV 300 Query 301 CGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPG 360 G ++L P A V VLAP VG I D+ HP + FGF A A+ WL M PG Sbjct 301 RGYDALEASLLMVPMAAVSLVLAPVVGRINDKVHPRWLTSFGFFCCAAAIFWLTGPMTPG 360 Query 361 TPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMA 420 + +W L++P LG+ AFVW+PL ATRNL PH AGA SGV+NA R +G+V+GSA++A Sbjct 361 SAVWELLVPMGLLGLGMAFVWAPLAAAATRNLPPHQAGAGSGVYNATRTVGSVVGSAAIA 420 Query 421 AFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVA 480 M +RI+A G+DA AG QLP V E F+ AM+++ LLPA G VA Sbjct 421 VLMDARISAN---GLDASAETAGGAGA--QLPAEVAERFSQAMAEATLLPAVALAVGFVA 475 Query 481 ALFL 484 LF Sbjct 476 VLFF 479 >gi|323357646|ref|YP_004224042.1| permease of the major facilitator superfamily [Microbacterium testaceum StLB037] gi|323274017|dbj|BAJ74162.1| permease of the major facilitator superfamily [Microbacterium testaceum StLB037] Length=519 Score = 472 bits (1214), Expect = 1e-130, Method: Compositional matrix adjust. Identities = 249/486 (52%), Positives = 330/486 (68%), Gaps = 8/486 (1%) Query 2 TTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLR---IGYATVVW 58 T + R + ++ R+PWPALWA+++GFFMI++D+T+V++ANP I A L VVW Sbjct 9 TASTRTGSHKTHERSPWPALWALVIGFFMILVDTTIVSVANPAIKAALDPNTNNLDNVVW 68 Query 59 VTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQG 118 VTSAYLL YAVP+L+ GRLGDRFGPKN+YL GL +FT+ASL CGL+ +LIAAR VQG Sbjct 69 VTSAYLLTYAVPLLITGRLGDRFGPKNIYLTGLAIFTLASLACGLAPSLEVLIAARAVQG 128 Query 119 VGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFV 178 +GA L+TPQT++ ITR FP RG A+G WG A VA+LVGPLAGG LVD +GWEWIFF+ Sbjct 129 LGAALMTPQTMAVITRTFPPQNRGAAMGLWGATAGVATLVGPLAGGLLVDGLGWEWIFFI 188 Query 179 NVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAV 238 N+PVG+IG I A L+P LP H+FD GV LS G+FLIVFGLQ+G+ +W WIW + Sbjct 189 NIPVGIIGFIAAVILVPQLPRTAHKFDILGVVLSAVGLFLIVFGLQEGEHYSWAAWIWGM 248 Query 239 IVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQ 298 + G+ M +FV+ QAR+ EPL+PL++F DRNFS++NL IA + F T M LP FY Q Sbjct 249 VAAGVVVMGVFVWTQARSKGEPLVPLDLFRDRNFSVANLAIAAVGFTVTSMALPQMFYLQ 308 Query 299 AVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMA 358 GL+PT +A+L P AI+ GVLAPF G ++DR+ P +L G ++ ++ + + Sbjct 309 LARGLTPTESALLLVPLAILSGVLAPFAGKLLDRTDPRFLLVPGLLLVGGSLGIYVALIL 368 Query 359 PGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSAS 418 PIW ++P +GV A +W PL TATRNL P AGA +G++N R +G+V+GSAS Sbjct 369 NDAPIWAFLIPSALMGVGNAGMWGPLATTATRNLPPRQAGAGAGIYNTTRTVGSVIGSAS 428 Query 419 MAAFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGI 478 +AAFM +R+ A +PG DA G LP V F+ AM QS+ LP V G+ Sbjct 429 IAAFMQARLEANLPGAADASASFGGG-----TLPPQVVTGFSQAMGQSLTLPIIVIGVGL 483 Query 479 VAALFL 484 VA LF+ Sbjct 484 VAVLFM 489 Lambda K H 0.325 0.138 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1307024972652 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40