BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1256c Length=405 Score E Sequences producing significant alignments: (Bits) Value gi|15608396|ref|NP_215772.1| cytochrome P450 130 CYP130 [Mycobac... 829 0.0 gi|163310981|pdb|2UUQ|A Chain A, Crystal Structure Of Cyp130 Fro... 828 0.0 gi|148822473|ref|YP_001287227.1| cytochrome P450 130 cyp130 [Myc... 827 0.0 gi|289446847|ref|ZP_06436591.1| cytochrome P450 130 cyp130 [Myco... 826 0.0 gi|254220877|pdb|2WH8|A Chain A, Interaction Of Mycobacterium Tu... 825 0.0 gi|237640433|pdb|2WGY|A Chain A, Crystal Structure Of The G243a ... 824 0.0 gi|167969579|ref|ZP_02551856.1| putative cytochrome p450 130 CYP... 820 0.0 gi|253799699|ref|YP_003032700.1| cytochrome P450 130 cyp130 [Myc... 819 0.0 gi|342862133|ref|ZP_08718776.1| cytochrome P450 [Mycobacterium c... 717 0.0 gi|240172647|ref|ZP_04751306.1| cytochrome P450 130A4 Cyp130A4 [... 716 0.0 gi|254819466|ref|ZP_05224467.1| putative cytochrome P450 130 [My... 712 0.0 gi|183984155|ref|YP_001852446.1| cytochrome P450 130A4 Cyp130A4 ... 710 0.0 gi|336458597|gb|EGO37564.1| cytochrome P450 [Mycobacterium avium... 704 0.0 gi|118465845|ref|YP_880646.1| cytochrome P450 130 [Mycobacterium... 701 0.0 gi|41408616|ref|NP_961452.1| hypothetical protein MAP2518 [Mycob... 699 0.0 gi|296170158|ref|ZP_06851755.1| possible Linalool 8-monooxygenas... 696 0.0 gi|289757354|ref|ZP_06516732.1| cytochrome P450 130 cyp130 [Myco... 673 0.0 gi|120405417|ref|YP_955246.1| cytochrome P450 [Mycobacterium van... 655 0.0 gi|145222817|ref|YP_001133495.1| cytochrome P450 [Mycobacterium ... 650 0.0 gi|126436551|ref|YP_001072242.1| cytochrome P450 [Mycobacterium ... 646 0.0 gi|108800926|ref|YP_641123.1| cytochrome P450 [Mycobacterium sp.... 642 0.0 gi|118470510|ref|YP_889288.1| cytochrome P450 [Mycobacterium sme... 636 2e-180 gi|169628497|ref|YP_001702146.1| cytochrome P450 [Mycobacterium ... 594 8e-168 gi|333989863|ref|YP_004522477.1| cytochrome P450 [Mycobacterium ... 594 9e-168 gi|226365193|ref|YP_002782976.1| cytochrome P450 [Rhodococcus op... 562 3e-158 gi|111022684|ref|YP_705656.1| cytochrome P450 [Rhodococcus josti... 561 6e-158 gi|312140383|ref|YP_004007719.1| cytochrome p450 monooxygenase [... 553 3e-155 gi|325676007|ref|ZP_08155690.1| P450 heme-thiolate protein [Rhod... 552 5e-155 gi|229494501|ref|ZP_04388264.1| putative cytochrome P450 123 [Rh... 540 2e-151 gi|226304632|ref|YP_002764590.1| cytochrome P450 [Rhodococcus er... 537 1e-150 gi|296179474|gb|ADG96480.1| cytochrome P450 [Gordonia cholestero... 535 5e-150 gi|326381886|ref|ZP_08203579.1| cytochrome P450 [Gordonia neofel... 531 1e-148 gi|296141452|ref|YP_003648695.1| cytochrome P450 [Tsukamurella p... 521 6e-146 gi|311744597|ref|ZP_07718396.1| P450 heme-thiolate protein [Aero... 506 2e-141 gi|326329198|ref|ZP_08195525.1| P450 heme-thiolate protein [Noca... 474 1e-131 gi|262200984|ref|YP_003272192.1| cytochrome P450 CYP124E1 [Gordo... 462 4e-128 gi|119718837|ref|YP_925802.1| RelA/SpoT domain-containing protei... 410 2e-112 gi|254774283|ref|ZP_05215799.1| hypothetical protein MaviaA2_063... 341 1e-91 gi|333918653|ref|YP_004492234.1| cytochrome P450 [Amycolicicoccu... 335 6e-90 gi|126437155|ref|YP_001072846.1| cytochrome P450 [Mycobacterium ... 263 5e-68 gi|119716393|ref|YP_923358.1| cytochrome P450 [Nocardioides sp. ... 259 7e-67 gi|333921949|ref|YP_004495530.1| cytochrome P450 [Amycolicicoccu... 253 5e-65 gi|296164721|ref|ZP_06847286.1| cytochrome P450 Cyp189A7 [Mycoba... 253 5e-65 gi|120401342|ref|YP_951171.1| cytochrome P450 [Mycobacterium van... 252 8e-65 gi|311742017|ref|ZP_07715827.1| P450 heme-thiolate protein [Aero... 251 1e-64 gi|254818816|ref|ZP_05223817.1| cytochrome P450 [Mycobacterium i... 251 2e-64 gi|240173182|ref|ZP_04751840.1| cytochrome P450 189A7 Cyp189A7 [... 249 6e-64 gi|342861362|ref|ZP_08718010.1| cytochrome P450 [Mycobacterium c... 249 7e-64 gi|118466989|ref|YP_882170.1| cytochrome P450 [Mycobacterium avi... 248 2e-63 gi|108800798|ref|YP_640995.1| cytochrome P450 [Mycobacterium sp.... 247 2e-63 >gi|15608396|ref|NP_215772.1| cytochrome P450 130 CYP130 [Mycobacterium tuberculosis H37Rv] gi|15840702|ref|NP_335739.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|148661043|ref|YP_001282566.1| putative cytochrome p450 130 CYP130 [Mycobacterium tuberculosis H37Ra] 27 more sequence titles Length=405 Score = 829 bits (2141), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/405 (100%), Positives = 405/405 (100%), Gaps = 0/405 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR Sbjct 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV Sbjct 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD Sbjct 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 Query 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM Sbjct 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 Query 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD Sbjct 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 Query 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA Sbjct 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 Query 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 >gi|163310981|pdb|2UUQ|A Chain A, Crystal Structure Of Cyp130 From Mycobacterium Tuberculosis In The Ligand-Free Form gi|163310982|pdb|2UVN|A Chain A, Crystal Structure Of Econazole-Bound Cyp130 From Mycobacterium Tuberculosis gi|163310983|pdb|2UVN|B Chain B, Crystal Structure Of Econazole-Bound Cyp130 From Mycobacterium Tuberculosis Length=414 Score = 828 bits (2138), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/405 (100%), Positives = 405/405 (100%), Gaps = 0/405 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR Sbjct 8 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 67 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV Sbjct 68 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 127 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD Sbjct 128 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 187 Query 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM Sbjct 188 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 247 Query 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD Sbjct 248 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 307 Query 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA Sbjct 308 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 367 Query 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 368 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 412 >gi|148822473|ref|YP_001287227.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis F11] gi|289554955|ref|ZP_06444165.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis KZN 605] gi|289761408|ref|ZP_06520786.1| cytochrome P450 130 [Mycobacterium tuberculosis GM 1503] gi|148721000|gb|ABR05625.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis F11] gi|289439587|gb|EFD22080.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis KZN 605] gi|289708914|gb|EFD72930.1| cytochrome P450 130 [Mycobacterium tuberculosis GM 1503] gi|328459445|gb|AEB04868.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis KZN 4207] gi|344219085|gb|AEM99715.1| cytochrome P450 130 CYP130 [Mycobacterium tuberculosis CTRI-2] Length=405 Score = 827 bits (2135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/405 (99%), Positives = 404/405 (99%), Gaps = 0/405 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR Sbjct 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV Sbjct 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 RKFVVERLEKLRANGGGDIVTELF PLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD Sbjct 121 RKFVVERLEKLRANGGGDIVTELFNPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 Query 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM Sbjct 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 Query 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD Sbjct 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 Query 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA Sbjct 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 Query 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 >gi|289446847|ref|ZP_06436591.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis CPHL_A] gi|289419805|gb|EFD17006.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis CPHL_A] Length=405 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/405 (99%), Positives = 404/405 (99%), Gaps = 0/405 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR Sbjct 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV Sbjct 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD Sbjct 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 Query 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM Sbjct 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 Query 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQ LARTTTRD Sbjct 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQELARTTTRD 300 Query 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA Sbjct 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA 360 Query 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 361 RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 >gi|254220877|pdb|2WH8|A Chain A, Interaction Of Mycobacterium Tuberculosis Cyp130 With Heterocyclic Arylamines gi|254220878|pdb|2WH8|B Chain B, Interaction Of Mycobacterium Tuberculosis Cyp130 With Heterocyclic Arylamines gi|254220879|pdb|2WH8|C Chain C, Interaction Of Mycobacterium Tuberculosis Cyp130 With Heterocyclic Arylamines gi|254220880|pdb|2WH8|D Chain D, Interaction Of Mycobacterium Tuberculosis Cyp130 With Heterocyclic Arylamines gi|254220881|pdb|2WHF|A Chain A, Interaction Of Mycobacterium Tuberculosis Cyp130 With Heterocyclic Arylamines Length=413 Score = 825 bits (2132), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/404 (100%), Positives = 404/404 (100%), Gaps = 0/404 (0%) Query 2 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD 61 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD Sbjct 8 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD 67 Query 62 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR 121 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR Sbjct 68 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR 127 Query 122 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG 181 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG Sbjct 128 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG 187 Query 182 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV 241 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV Sbjct 188 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV 247 Query 242 TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV 301 TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV Sbjct 248 TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV 307 Query 302 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR 361 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR Sbjct 308 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR 367 Query 362 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 368 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 411 >gi|237640433|pdb|2WGY|A Chain A, Crystal Structure Of The G243a Mutant Of Cyp130 From M. Tuberculosis Length=413 Score = 824 bits (2128), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/404 (99%), Positives = 403/404 (99%), Gaps = 0/404 (0%) Query 2 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD 61 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD Sbjct 8 TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARD 67 Query 62 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR 121 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR Sbjct 68 HQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVR 127 Query 122 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG 181 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG Sbjct 128 KFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDG 187 Query 182 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV 241 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV Sbjct 188 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV 247 Query 242 TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV 301 T GNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV Sbjct 248 TAGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV 307 Query 302 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR 361 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR Sbjct 308 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR 367 Query 362 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 368 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 411 >gi|167969579|ref|ZP_02551856.1| putative cytochrome p450 130 CYP130 [Mycobacterium tuberculosis H37Ra] gi|254364154|ref|ZP_04980200.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis str. Haarlem] gi|294994813|ref|ZP_06800504.1| cytochrome P450 [Mycobacterium tuberculosis 210] 26 more sequence titles Length=401 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/401 (100%), Positives = 401/401 (100%), Gaps = 0/401 (0%) Query 5 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT 64 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT Sbjct 1 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT 60 Query 65 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV 124 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV Sbjct 61 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV 120 Query 125 VERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT 184 VERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT Sbjct 121 VERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT 180 Query 185 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 244 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG Sbjct 181 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 240 Query 245 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 304 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG Sbjct 241 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 300 Query 305 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 364 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC Sbjct 301 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 360 Query 365 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 361 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 401 >gi|253799699|ref|YP_003032700.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis KZN 1435] gi|254550263|ref|ZP_05140710.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|297633805|ref|ZP_06951585.1| cytochrome P450 [Mycobacterium tuberculosis KZN 4207] gi|297730791|ref|ZP_06959909.1| cytochrome P450 [Mycobacterium tuberculosis KZN R506] gi|313658123|ref|ZP_07815003.1| cytochrome P450 [Mycobacterium tuberculosis KZN V2475] gi|253321202|gb|ACT25805.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis KZN 1435] Length=401 Score = 819 bits (2116), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/401 (99%), Positives = 400/401 (99%), Gaps = 0/401 (0%) Query 5 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT 64 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT Sbjct 1 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT 60 Query 65 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV 124 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV Sbjct 61 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV 120 Query 125 VERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT 184 VERLEKLRANGGGDIVTELF PLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT Sbjct 121 VERLEKLRANGGGDIVTELFNPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT 180 Query 185 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 244 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG Sbjct 181 GALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 240 Query 245 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 304 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG Sbjct 241 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 300 Query 305 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 364 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC Sbjct 301 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 360 Query 365 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS Sbjct 361 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 401 >gi|342862133|ref|ZP_08718776.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342130437|gb|EGT83752.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=413 Score = 717 bits (1852), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/413 (85%), Positives = 374/413 (91%), Gaps = 8/413 (1%) Query 1 MTSVMSHE----FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVW 56 M +V+SHE FQLATA+TWPNPWPMYRALRDHDPVHHV+P + PE DYYVLSRHADVW Sbjct 1 MAAVVSHEAPVKFQLATADTWPNPWPMYRALRDHDPVHHVIPAKHPEDDYYVLSRHADVW 60 Query 57 SAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETV 116 +AARDH+T+SSAQGLTVNYG+LEMIGL + PP VMQDPPVHT+FRKLVSRGFTPRQVE V Sbjct 61 AAARDHETYSSAQGLTVNYGDLEMIGLQENPPFVMQDPPVHTQFRKLVSRGFTPRQVEAV 120 Query 117 EPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAA 176 EP VR+FVVER+E LR+NGGGDIV ELFKPLPSMVVAHYLGVPEEDW QFDGWTQAIVAA Sbjct 121 EPKVREFVVERIEGLRSNGGGDIVAELFKPLPSMVVAHYLGVPEEDWAQFDGWTQAIVAA 180 Query 177 NAVDGATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS 232 N +G GAL DAVGSMMAYFT LIERRRTEP DD ISHLVAAGVGADGD AGTLS Sbjct 181 NTAEGGVAGALETVGDAVGSMMAYFTALIERRRTEPEDDTISHLVAAGVGADGDVAGTLS 240 Query 233 ILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQG 292 ILAFTFTMVTGGNDTVTGMLGGSMPLLH+RPDQRRLL++DP +PDAVEELLR+TSPVQG Sbjct 241 ILAFTFTMVTGGNDTVTGMLGGSMPLLHQRPDQRRLLVNDPGRVPDAVEELLRMTSPVQG 300 Query 293 LARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAH 352 LARTTTRDVT+G+TTIPAGRRVLLLYGSANRDERQYG DA ELD+TRCPRNILTFSHGAH Sbjct 301 LARTTTRDVTVGETTIPAGRRVLLLYGSANRDERQYGSDAGELDLTRCPRNILTFSHGAH 360 Query 353 HCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 HCLGAAAARMQ VALTEL+ARCPDF+V ES IVW+GGSYVRRPLSVP RV S Sbjct 361 HCLGAAAARMQSCVALTELMARCPDFDVDESGIVWAGGSYVRRPLSVPIRVKS 413 >gi|240172647|ref|ZP_04751306.1| cytochrome P450 130A4 Cyp130A4 [Mycobacterium kansasii ATCC 12478] Length=402 Score = 716 bits (1848), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/401 (87%), Positives = 364/401 (91%), Gaps = 4/401 (0%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 FQLATAETW NPWPMYRALRDHDPVHHVVPP P++DYYVLSRHADVW+AARDHQTFSSA Sbjct 2 FQLATAETWANPWPMYRALRDHDPVHHVVPPDSPDHDYYVLSRHADVWAAARDHQTFSSA 61 Query 69 QGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERL 128 QGLTVNYGELE+IGL D PPMVMQDPP+HTEFRKLVSRGFTPRQVE VEP V++FVVER+ Sbjct 62 QGLTVNYGELELIGLQDNPPMVMQDPPLHTEFRKLVSRGFTPRQVEAVEPKVKEFVVERI 121 Query 129 EKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGAL- 187 E+LRANGGGDI ELFKPLPSMVVAHYLGVPEED QFDGWTQAIVAAN +G GAL Sbjct 122 ERLRANGGGDIAAELFKPLPSMVVAHYLGVPEEDRAQFDGWTQAIVAANTGEGGIAGALE 181 Query 188 ---DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 244 DAVGSMMAYFTGLIERRRTEP DD ISHLVAAGVGADGD AGTLSILAFTFTMVTGG Sbjct 182 TVGDAVGSMMAYFTGLIERRRTEPGDDTISHLVAAGVGADGDIAGTLSILAFTFTMVTGG 241 Query 245 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 304 NDTVTGMLGGSMPLL +RPDQR+LL+D PE IPDA+EELLRLTSPVQGL RT T DVTIG Sbjct 242 NDTVTGMLGGSMPLLQQRPDQRQLLVDQPERIPDAIEELLRLTSPVQGLTRTVTNDVTIG 301 Query 305 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 364 DTT+PAGR+VLLLYGSANRDERQYG DA ELDVTRCPRNILTFSHGAHHCLGAAAARMQ Sbjct 302 DTTVPAGRKVLLLYGSANRDERQYGSDAGELDVTRCPRNILTFSHGAHHCLGAAAARMQS 361 Query 365 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RVALTELL RCPDFE+ E IVWSGGSYVRRPLSVPFRV S Sbjct 362 RVALTELLLRCPDFEIDEPAIVWSGGSYVRRPLSVPFRVKS 402 >gi|254819466|ref|ZP_05224467.1| putative cytochrome P450 130 [Mycobacterium intracellulare ATCC 13950] Length=409 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/401 (87%), Positives = 364/401 (91%), Gaps = 4/401 (0%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 FQLATA TW NPWPMYRALRDHDPVHHVVP PE+DYYVLSRHADVW+AARDH+TFSSA Sbjct 9 FQLATAATWSNPWPMYRALRDHDPVHHVVPANSPEHDYYVLSRHADVWAAARDHETFSSA 68 Query 69 QGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERL 128 +GLTVNY +LE+IGL D PP VMQDPPVHT+FRKLVSRGFTPRQVE VEP VR+FVVER+ Sbjct 69 KGLTVNYDDLELIGLQDNPPFVMQDPPVHTQFRKLVSRGFTPRQVEAVEPKVREFVVERI 128 Query 129 EKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGAL- 187 E LRA GGGDIVTELFKPLPSMVVAHYLGVPEEDW QFDGWTQAIVAAN +G GAL Sbjct 129 EGLRAAGGGDIVTELFKPLPSMVVAHYLGVPEEDWVQFDGWTQAIVAANTAEGGVAGALE 188 Query 188 ---DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 244 DAVGSMMAYFTGLIERRRT+P DD ISHLV AGVGADGD AGTLSILAFTFTMVTGG Sbjct 189 TVGDAVGSMMAYFTGLIERRRTDPEDDTISHLVTAGVGADGDVAGTLSILAFTFTMVTGG 248 Query 245 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 304 NDTVTGMLGGSMPLLH RPDQR+LL+D+PE I DAVEELLR+TSPVQGLARTTTR+VTIG Sbjct 249 NDTVTGMLGGSMPLLHERPDQRKLLVDNPELITDAVEELLRMTSPVQGLARTTTREVTIG 308 Query 305 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 364 DTTIPAGRR LLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQ Sbjct 309 DTTIPAGRRALLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQS 368 Query 365 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RVALTELLARCPDFEV ES I W+GG+YVRRPLSVP RV S Sbjct 369 RVALTELLARCPDFEVDESGIAWAGGNYVRRPLSVPIRVGS 409 >gi|183984155|ref|YP_001852446.1| cytochrome P450 130A4 Cyp130A4 [Mycobacterium marinum M] gi|183177481|gb|ACC42591.1| cytochrome P450 130A4 Cyp130A4 [Mycobacterium marinum M] Length=413 Score = 710 bits (1833), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/401 (87%), Positives = 361/401 (91%), Gaps = 4/401 (0%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 FQLATA TWP+PWPMYRALRD DPVHHV+P +P+ DYYVLSRHADVW+AARDHQTFSSA Sbjct 13 FQLATAATWPDPWPMYRALRDQDPVHHVIPAHQPDQDYYVLSRHADVWAAARDHQTFSSA 72 Query 69 QGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERL 128 QGLTVNYG+LEMIGL D PPMVMQDPP HTEFRKLVSRGFTPRQVE VEP VR FVVER+ Sbjct 73 QGLTVNYGDLEMIGLQDNPPMVMQDPPAHTEFRKLVSRGFTPRQVEAVEPKVRDFVVERI 132 Query 129 EKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGAL- 187 E+LRA GGGDIVTELFKPLPSMVVAHYLGVPE+D TQFDGWTQAIVAAN +G GAL Sbjct 133 ERLRAQGGGDIVTELFKPLPSMVVAHYLGVPEQDRTQFDGWTQAIVAANTAEGGIAGALA 192 Query 188 ---DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGG 244 DAVGSMMAYFT LIERRR +P DD ISHLVAAGVGADGD AGTLSILAFTFTMVTGG Sbjct 193 TVGDAVGSMMAYFTSLIERRRAKPEDDTISHLVAAGVGADGDIAGTLSILAFTFTMVTGG 252 Query 245 NDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIG 304 NDTVTGMLGGSMPLLHRRPDQRRLL D+PE I DAVEELLRLTSPVQGLART T DVTIG Sbjct 253 NDTVTGMLGGSMPLLHRRPDQRRLLTDNPELITDAVEELLRLTSPVQGLARTVTHDVTIG 312 Query 305 DTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQC 364 + TIPAGRR LLLYGSANRDERQYGPDA ELDV RCPRNILTFSHGAHHCLGAAAARMQ Sbjct 313 NVTIPAGRRALLLYGSANRDERQYGPDAGELDVRRCPRNILTFSHGAHHCLGAAAARMQS 372 Query 365 RVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 RVALTELLARCPDFEV ESRIVWSGGSYVRRPLS+PF V S Sbjct 373 RVALTELLARCPDFEVDESRIVWSGGSYVRRPLSLPFEVRS 413 >gi|336458597|gb|EGO37564.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=413 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/413 (84%), Positives = 368/413 (90%), Gaps = 8/413 (1%) Query 1 MTSVMSHE----FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVW 56 MTS +SH F+L A+TW +PWPMYRALRDHDPVHHVVPP+RPE+DYYVLSRHADVW Sbjct 1 MTSTVSHNVPVAFELPNADTWADPWPMYRALRDHDPVHHVVPPKRPEHDYYVLSRHADVW 60 Query 57 SAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETV 116 +AARDH+TFSSA+GLTVNY +LE+IGL D PP VMQDPPVHTEFRKLVSR FTPRQVE V Sbjct 61 AAARDHETFSSAKGLTVNYDDLELIGLQDNPPFVMQDPPVHTEFRKLVSRSFTPRQVEAV 120 Query 117 EPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAA 176 EP VR FVVER+E+LRA GGGDIV ELFKPLPSMVVAHYLGVPEED QFDGWT+AIVAA Sbjct 121 EPKVRDFVVERIERLRAAGGGDIVAELFKPLPSMVVAHYLGVPEEDRAQFDGWTEAIVAA 180 Query 177 NAVDGATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS 232 N DG GAL DAV SMMAYFTGLIERRRT+P DD ISHLV+AGVGADGD AGTLS Sbjct 181 NTADGGVAGALGSAGDAVTSMMAYFTGLIERRRTDPEDDTISHLVSAGVGADGDIAGTLS 240 Query 233 ILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQG 292 +LAFTFTMVTGGNDT TGMLGGSMPLLH+RPDQR+ L+D+PE IPDAVEELLRLTSPVQG Sbjct 241 VLAFTFTMVTGGNDTTTGMLGGSMPLLHQRPDQRQRLVDEPELIPDAVEELLRLTSPVQG 300 Query 293 LARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAH 352 LARTTTRDVTIG TTIPAGRRVLLLYGSANRDERQYGPDA ELDV RCPRNILTFSHGAH Sbjct 301 LARTTTRDVTIGRTTIPAGRRVLLLYGSANRDERQYGPDAGELDVARCPRNILTFSHGAH 360 Query 353 HCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 HCLGAAAARMQ RVALTELLARCPDFEV ES IVW+GG+YVRRPLSVP RV S Sbjct 361 HCLGAAAARMQSRVALTELLARCPDFEVDESGIVWAGGNYVRRPLSVPIRVKS 413 >gi|118465845|ref|YP_880646.1| cytochrome P450 130 [Mycobacterium avium 104] gi|118167132|gb|ABK68029.1| putative cytochrome P450 130 [Mycobacterium avium 104] Length=409 Score = 701 bits (1810), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/409 (85%), Positives = 366/409 (90%), Gaps = 8/409 (1%) Query 5 MSHE----FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MSH F+L A+TW +PWPMYRALRDHDPVHHVVPP+RPE+DYYVLSRHADVW+AAR Sbjct 1 MSHNVPVAFELPNADTWADPWPMYRALRDHDPVHHVVPPKRPEHDYYVLSRHADVWAAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DH+TFSSA+GLTVNY +LE+IGL D PP VMQDPPVHTEFRKLVSRGFTPRQVE VEP V Sbjct 61 DHETFSSAKGLTVNYDDLELIGLQDNPPFVMQDPPVHTEFRKLVSRGFTPRQVEAVEPKV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 R FVVER+E+LRA GGGDIV ELFKPLPSMVVAHYLGVPEED QFDGWT+AIVAAN D Sbjct 121 RDFVVERIERLRAAGGGDIVAELFKPLPSMVVAHYLGVPEEDRAQFDGWTEAIVAANTAD 180 Query 181 GATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAF 236 G GAL DAV SMMAYFTGLIERRRT+P DD ISHLV+AGVGADGD AGTLS+LAF Sbjct 181 GGVAGALGSAGDAVTSMMAYFTGLIERRRTDPEDDTISHLVSAGVGADGDIAGTLSVLAF 240 Query 237 TFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLART 296 TFTMVTGGNDT TGMLGGSMPLLH+RPDQR+ L+D+PE IPDAVEELLRLTSPVQGLART Sbjct 241 TFTMVTGGNDTTTGMLGGSMPLLHQRPDQRQRLVDEPELIPDAVEELLRLTSPVQGLART 300 Query 297 TTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLG 356 TTRDVTIG TTIPAGRRVLLLYGSANRDERQYGPDA ELDV RCPRNILTFSHGAHHCLG Sbjct 301 TTRDVTIGRTTIPAGRRVLLLYGSANRDERQYGPDAGELDVARCPRNILTFSHGAHHCLG 360 Query 357 AAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 AAAARMQ RVALTELLARCPDFEV ES IVW+GG+YVRRPLSVP RV S Sbjct 361 AAAARMQSRVALTELLARCPDFEVDESGIVWAGGNYVRRPLSVPIRVKS 409 >gi|41408616|ref|NP_961452.1| hypothetical protein MAP2518 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396974|gb|AAS04835.1| hypothetical protein MAP_2518 [Mycobacterium avium subsp. paratuberculosis K-10] Length=409 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/409 (84%), Positives = 365/409 (90%), Gaps = 8/409 (1%) Query 5 MSHE----FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MSH F+L A+TW +PWPMYRALRDHDPVHHVVPP+RPE+DYYVLSRHADVW+AAR Sbjct 1 MSHNVPVAFELPNADTWADPWPMYRALRDHDPVHHVVPPKRPEHDYYVLSRHADVWAAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DH+TFSSA+GLTVNY +LE+IGL D PP VMQDPPVHTEFRKLVSR FTPRQVE VEP V Sbjct 61 DHETFSSAKGLTVNYDDLELIGLQDNPPFVMQDPPVHTEFRKLVSRSFTPRQVEAVEPKV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 R FVVER+E+LRA GGGDIV ELFKPLPSMVVAHYLGVPEED QFDGWT+AIVAAN D Sbjct 121 RDFVVERIERLRAAGGGDIVAELFKPLPSMVVAHYLGVPEEDRAQFDGWTEAIVAANTAD 180 Query 181 GATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAF 236 G GAL DAV SMMAYFTGLIERRRT+P DD ISHLV+AGVGADGD AGTLS+LAF Sbjct 181 GGVAGALGSAGDAVTSMMAYFTGLIERRRTDPEDDTISHLVSAGVGADGDIAGTLSVLAF 240 Query 237 TFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLART 296 TFTMVTGGNDT TGMLGGSMPLLH+RPDQR+ L+D+PE IPDAVEELLRLTSPVQGLART Sbjct 241 TFTMVTGGNDTTTGMLGGSMPLLHQRPDQRQRLVDEPELIPDAVEELLRLTSPVQGLART 300 Query 297 TTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLG 356 TTRDVTIG TTIPAGRRVLLLYGSANRDERQYGPDA ELDV RCPRNILTFSHGAHHCLG Sbjct 301 TTRDVTIGRTTIPAGRRVLLLYGSANRDERQYGPDAGELDVARCPRNILTFSHGAHHCLG 360 Query 357 AAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 AAAARMQ RVALTELLARCPDFEV ES IVW+GG+YVRRPLSVP RV S Sbjct 361 AAAARMQSRVALTELLARCPDFEVDESGIVWAGGNYVRRPLSVPIRVKS 409 >gi|296170158|ref|ZP_06851755.1| possible Linalool 8-monooxygenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895184|gb|EFG74899.1| possible Linalool 8-monooxygenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=416 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/414 (84%), Positives = 365/414 (89%), Gaps = 11/414 (2%) Query 1 MTSVMSHE----FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVW 56 M +VMSH+ F+LATA+TW NPWPMYRALRD DPVHHVVP +RP++DYYVLSRHADVW Sbjct 1 MAAVMSHDAPAVFELATADTWRNPWPMYRALRDRDPVHHVVPAKRPDHDYYVLSRHADVW 60 Query 57 SAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETV 116 +AARDH+TFSSAQGLTVNYG+LEMIGL D PP VMQDPPVHTEFRKLVSRGFTPRQVE V Sbjct 61 AAARDHETFSSAQGLTVNYGDLEMIGLQDNPPFVMQDPPVHTEFRKLVSRGFTPRQVEAV 120 Query 117 EPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAA 176 EP VR+FVVER+E+LRA GGGDIVTELFKPLPSMVVAHYLGVPE D QFD WT IVAA Sbjct 121 EPKVREFVVERIERLRAAGGGDIVTELFKPLPSMVVAHYLGVPEADRAQFDRWTDVIVAA 180 Query 177 NAVDGATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADG---DTAG 229 N DG GAL DAVGSMMAYFTGLIERRRTEP DD ISHLV+AG+G+ G D AG Sbjct 181 NTADGGVAGALETVGDAVGSMMAYFTGLIERRRTEPGDDTISHLVSAGIGSKGGAGDVAG 240 Query 230 TLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSP 289 LS+LAFTFTMVTGGNDT TGMLGGSMPLLH+RPDQRRLL+DD IPDAVEELLRLTSP Sbjct 241 MLSVLAFTFTMVTGGNDTTTGMLGGSMPLLHQRPDQRRLLVDDMGSIPDAVEELLRLTSP 300 Query 290 VQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSH 349 VQGLARTTTRDVTIGDTTIPAGR+V LLYGSANRDERQYGPDA ELDVTR PRNILTFSH Sbjct 301 VQGLARTTTRDVTIGDTTIPAGRKVFLLYGSANRDERQYGPDAGELDVTRRPRNILTFSH 360 Query 350 GAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 GAHHCLGAAAARMQ RVALTELL RCPDFEV ES IVWSGGSYVRRPLSVP R+ Sbjct 361 GAHHCLGAAAARMQSRVALTELLTRCPDFEVDESAIVWSGGSYVRRPLSVPIRM 414 >gi|289757354|ref|ZP_06516732.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis T85] gi|289712918|gb|EFD76930.1| cytochrome P450 130 cyp130 [Mycobacterium tuberculosis T85] Length=330 Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/330 (100%), Positives = 330/330 (100%), Gaps = 0/330 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR Sbjct 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV Sbjct 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD Sbjct 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD 180 Query 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM Sbjct 181 GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM 240 Query 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD Sbjct 241 VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD 300 Query 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGP 330 VTIGDTTIPAGRRVLLLYGSANRDERQYGP Sbjct 301 VTIGDTTIPAGRRVLLLYGSANRDERQYGP 330 >gi|120405417|ref|YP_955246.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119958235|gb|ABM15240.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=413 Score = 655 bits (1689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/412 (79%), Positives = 348/412 (85%), Gaps = 8/412 (1%) Query 1 MTSVMSH----EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVW 56 MT+V+SH F LA A TW +PWPMYRALRDHDPVHHVVP RP +DYYVLSRHAD+W Sbjct 1 MTAVLSHGSPVHFALADASTWADPWPMYRALRDHDPVHHVVPEDRPNHDYYVLSRHADIW 60 Query 57 SAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETV 116 +AARDHQTFSSA GLTVNYGEL++IGL D PPMVMQDPPVHTEFRKLV+RGFTPRQVE V Sbjct 61 AAARDHQTFSSALGLTVNYGELDLIGLADNPPMVMQDPPVHTEFRKLVARGFTPRQVEAV 120 Query 117 EPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAA 176 EP V FVV+R+E LRANGGGDIV ELFKPLPSMVVAHYLGVP+ED +FDGWT AIVAA Sbjct 121 EPKVHDFVVDRIEHLRANGGGDIVAELFKPLPSMVVAHYLGVPDEDRGKFDGWTDAIVAA 180 Query 177 NAVDGATTGALD----AVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS 232 N G GALD A+G MM+YFT LIERRRTEP DD ISHLVAAGVGADGD +G LS Sbjct 181 NTSAGGLGGALDTLGDALGEMMSYFTALIERRRTEPEDDTISHLVAAGVGADGDISGVLS 240 Query 233 ILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQG 292 ILAFTFTMVTGGNDT TGMLGGS+ LLHRRPDQR +L ++P+ IPDAV+E LRLTSPVQ Sbjct 241 ILAFTFTMVTGGNDTTTGMLGGSVQLLHRRPDQRTMLAENPDLIPDAVDEFLRLTSPVQM 300 Query 293 LARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAH 352 L RT T DVTIGD TIP GRRV+ LYGS NRDERQYG DA ELDVTR PRNILTFSHGAH Sbjct 301 LGRTVTHDVTIGDVTIPEGRRVMFLYGSGNRDERQYGDDAGELDVTRKPRNILTFSHGAH 360 Query 353 HCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVT 404 HCLGAAAARMQ RVALTELL R PDFEV ES I W+GGSYVRRP+SVPF VT Sbjct 361 HCLGAAAARMQSRVALTELLTRIPDFEVDESGIAWAGGSYVRRPVSVPFTVT 412 >gi|145222817|ref|YP_001133495.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315443284|ref|YP_004076163.1| cytochrome P450 [Mycobacterium sp. Spyr1] gi|145215303|gb|ABP44707.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|315261587|gb|ADT98328.1| cytochrome P450 [Mycobacterium sp. Spyr1] Length=412 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/413 (78%), Positives = 353/413 (86%), Gaps = 9/413 (2%) Query 1 MTSVMSH----EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVW 56 MT+V+SH F+ A A TW +PWPMYRALRDHDPVHHVVP P++DYYVLSRHAD+W Sbjct 1 MTAVLSHGSPARFEPANASTWRDPWPMYRALRDHDPVHHVVPAD-PQHDYYVLSRHADIW 59 Query 57 SAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETV 116 +AARDH+TFSSAQGLTVNYGEL++IGL D PPMVMQDPP HTEFR+LV+RGFTPRQVE V Sbjct 60 AAARDHETFSSAQGLTVNYGELDLIGLADNPPMVMQDPPGHTEFRRLVARGFTPRQVEAV 119 Query 117 EPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAA 176 EP VR+FVVER+E+LRA+GGGDIV ELFKPLPSMVVAHYLGVP+ED +FDGWT AIVAA Sbjct 120 EPKVREFVVERIERLRADGGGDIVAELFKPLPSMVVAHYLGVPDEDRGKFDGWTDAIVAA 179 Query 177 NAVDGATTGAL----DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS 232 N DG GAL DA+G MM YFT LIERRR+EPADD +SHLVAAGVGADGD +G LS Sbjct 180 NTTDGGIAGALGTLGDALGEMMGYFTALIERRRSEPADDTVSHLVAAGVGADGDISGVLS 239 Query 233 ILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQG 292 ILAFTFTMVTGGNDT TGMLGGS+ LLH+RPDQRRLL D+P IPDAV+E LRLTSPVQ Sbjct 240 ILAFTFTMVTGGNDTTTGMLGGSVQLLHQRPDQRRLLADNPNLIPDAVDEFLRLTSPVQM 299 Query 293 LARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAH 352 L RT TRDVT+ D TIP GRRV+ LYGS NRDER +G DA ELDVTR PRNILTFSHGAH Sbjct 300 LGRTVTRDVTLHDVTIPEGRRVMFLYGSGNRDERHFGDDAGELDVTRRPRNILTFSHGAH 359 Query 353 HCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 HCLGAAAARMQ RVALTELL R P+FEV ES IVW+GGSYVRRPLSVPF VTS Sbjct 360 HCLGAAAARMQSRVALTELLTRIPNFEVDESGIVWAGGSYVRRPLSVPFTVTS 412 >gi|126436551|ref|YP_001072242.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236351|gb|ABN99751.1| cytochrome P450 [Mycobacterium sp. JLS] Length=398 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/403 (80%), Positives = 344/403 (86%), Gaps = 9/403 (2%) Query 1 MTSVMSH--EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ +SH F+LATAETW NPWPMY ALRDHDPVHHV+PP PE DYYVLSRHADVW A Sbjct 1 MTTNVSHAARFELATAETWTNPWPMYAALRDHDPVHHVLPPAAPERDYYVLSRHADVWRA 60 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARDH+TFSSAQGLTVNYGELEMIGL D PP VMQDPP HTEFRKLVSRGFTPRQVE VEP Sbjct 61 ARDHETFSSAQGLTVNYGELEMIGLADNPPFVMQDPPTHTEFRKLVSRGFTPRQVEDVEP 120 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FV+ER+E+LRA+GGGDIV ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAAN Sbjct 121 AVREFVIERIERLRADGGGDIVRELFKPLPSMVVAHYLGVPEADRAQFDGWTEAIVAANT 180 Query 179 VDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTF 238 TGA DA+G+MM YF LIERRR EP DD ISHLVAAGV L +LAFTF Sbjct 181 ESAGVTGAGDAIGAMMGYFAELIERRRREPGDDTISHLVAAGV-------DVLPVLAFTF 233 Query 239 TMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTT 298 TMVTGGNDT TGMLGG++ LLH+RPDQRRLL DP I DAV+E LRLTSPVQGLART T Sbjct 234 TMVTGGNDTTTGMLGGTVQLLHQRPDQRRLLAGDPGLIADAVDEFLRLTSPVQGLARTAT 293 Query 299 RDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAA 358 RDVT+ DTTIPAGR+VLLLYGSANRDER++GPDAAELDVTR PRNILTFSHGAH CLGAA Sbjct 294 RDVTVADTTIPAGRKVLLLYGSANRDEREFGPDAAELDVTRRPRNILTFSHGAHFCLGAA 353 Query 359 AARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF 401 AARMQ RVALTELLARCPDF V E+ IVW+GGSYVRRPLSVPF Sbjct 354 AARMQSRVALTELLARCPDFTVDEAGIVWAGGSYVRRPLSVPF 396 >gi|108800926|ref|YP_641123.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119870066|ref|YP_940018.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108771345|gb|ABG10067.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119696155|gb|ABL93228.1| cytochrome P450 [Mycobacterium sp. KMS] Length=398 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/403 (79%), Positives = 343/403 (86%), Gaps = 9/403 (2%) Query 1 MTSVMSH--EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ +SH F+LATAETW NPWPMY ALRDHDPVHHV+PP PE DYYVLSRHADVW A Sbjct 1 MTTNVSHAARFELATAETWTNPWPMYAALRDHDPVHHVLPPAAPERDYYVLSRHADVWRA 60 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARDH+TFSSAQGLTVNYGELEMIGL D PP VMQDPP HTEFRKLVSRGFTPRQVE VEP Sbjct 61 ARDHETFSSAQGLTVNYGELEMIGLADNPPFVMQDPPTHTEFRKLVSRGFTPRQVEDVEP 120 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FV+ER+E+LRA+GGGDIV ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAAN Sbjct 121 AVREFVIERIERLRADGGGDIVRELFKPLPSMVVAHYLGVPEADRAQFDGWTEAIVAANT 180 Query 179 VDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTF 238 TGA DA+G+M+ YF LIERRR EP DD ISHLVAAGV L +LAFTF Sbjct 181 ESAGVTGAGDAIGAMIGYFAELIERRRREPGDDTISHLVAAGV-------DVLPVLAFTF 233 Query 239 TMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTT 298 TMVTGGNDT TGMLGG++ LLH+RPDQRRLL DP I DAV+E LRLTSPVQGLART T Sbjct 234 TMVTGGNDTTTGMLGGTVQLLHQRPDQRRLLAGDPGLIADAVDEFLRLTSPVQGLARTAT 293 Query 299 RDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAA 358 RDVT+ DTTIPAGR+VLLLYGSANRDER++G DAAELDVTR PRNILTFSHGAH CLGAA Sbjct 294 RDVTVADTTIPAGRKVLLLYGSANRDEREFGSDAAELDVTRRPRNILTFSHGAHFCLGAA 353 Query 359 AARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF 401 AARMQ RVALTELLARCPDF V E+ IVW+GGSYVRRPLSVPF Sbjct 354 AARMQSRVALTELLARCPDFTVDEAGIVWAGGSYVRRPLSVPF 396 >gi|118470510|ref|YP_889288.1| cytochrome P450 [Mycobacterium smegmatis str. MC2 155] gi|118171797|gb|ABK72693.1| putative cytochrome P450 123 [Mycobacterium smegmatis str. MC2 155] Length=406 Score = 636 bits (1640), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 313/405 (78%), Positives = 344/405 (85%), Gaps = 5/405 (1%) Query 1 MTSVMSH---EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWS 57 M + +SH F+LA A+TW +PW MY ALRDHDPVHHVVPP+RP +DY+VLSRHAD+W+ Sbjct 1 MGADLSHPAVAFELANADTWADPWDMYTALRDHDPVHHVVPPERPHHDYFVLSRHADIWA 60 Query 58 AARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVE 117 AARDH+T+SSAQGLTVNYGELE+IGL D PP VMQDPP HTEFRKLVSRGFTPRQVE VE Sbjct 61 AARDHETYSSAQGLTVNYGELELIGLADNPPFVMQDPPTHTEFRKLVSRGFTPRQVEAVE 120 Query 118 PTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAAN 177 P VR+FVVERLE+LRA GGGDIV ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAAN Sbjct 121 PQVREFVVERLERLRAEGGGDIVAELFKPLPSMVVAHYLGVPEADRAQFDGWTEAIVAAN 180 Query 178 AVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFT 237 + G+ GA DAV SM YF LIERRR EP DD ISHLVAA GAD + LSILAFT Sbjct 181 SEAGSALGAGDAVMSMTGYFAELIERRRREPGDDTISHLVAA--GADDEAVDVLSILAFT 238 Query 238 FTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTT 297 FTMVTGGNDT TGMLGG++ LL + PDQRR+L DDP+ IPDAV+E LRLTSPVQGLART Sbjct 239 FTMVTGGNDTTTGMLGGAVQLLQQHPDQRRVLTDDPDLIPDAVDEFLRLTSPVQGLARTA 298 Query 298 TRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGA 357 TRDVTIGDTTIPAGR+VLLLYGS NRDER++GPDAA+LDV R PRNILTFSHGAH CLGA Sbjct 299 TRDVTIGDTTIPAGRKVLLLYGSGNRDEREFGPDAAQLDVRRRPRNILTFSHGAHFCLGA 358 Query 358 AAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFR 402 AAARMQ RVALTELL RCPDF V +VW+GGSYVRRPLSVPFR Sbjct 359 AAARMQSRVALTELLTRCPDFTVDLDAVVWAGGSYVRRPLSVPFR 403 >gi|169628497|ref|YP_001702146.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169240464|emb|CAM61492.1| Probable cytochrome P450 [Mycobacterium abscessus] Length=413 Score = 594 bits (1532), Expect = 8e-168, Method: Compositional matrix adjust. Identities = 294/402 (74%), Positives = 322/402 (81%), Gaps = 15/402 (3%) Query 12 ATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGL 71 TA+ W NPWPMY ALRDHDPVHHVVP P+ DYYVL+RHADV+ AARD +TFSSA+GL Sbjct 16 GTADNWTNPWPMYAALRDHDPVHHVVPEYTPDQDYYVLTRHADVYEAARDWETFSSARGL 75 Query 72 TVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKL 131 TV YG+LE G+ D PPMVMQDPP HTEFRKLVSRGFTPRQV VEP VR+FVV+RLE+L Sbjct 76 TVTYGDLEKTGMGDNPPMVMQDPPTHTEFRKLVSRGFTPRQVTAVEPKVREFVVQRLERL 135 Query 132 RANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALD--- 188 + G GDIV ELFKPLPSMVVAHYLGVPEED TQFD WT IVAA A+ GA+D Sbjct 136 KERGEGDIVVELFKPLPSMVVAHYLGVPEEDRTQFDAWTDGIVAA-----ASGGAIDIEA 190 Query 189 -------AVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV 241 +G +M YFTGLIERRR EP DD +SHLVAAGVGADGD +GTL IL F FTMV Sbjct 191 MQGEVAQTIGELMMYFTGLIERRRAEPEDDTVSHLVAAGVGADGDISGTLQILGFAFTMV 250 Query 242 TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDV 301 TGGNDT TGMLGG++ LLH+ P QR+ L+DDP IP AVEE LRLTSPVQGLART TRDV Sbjct 251 TGGNDTTTGMLGGAIQLLHQNPAQRQKLIDDPSLIPGAVEEFLRLTSPVQGLARTATRDV 310 Query 302 TIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAAR 361 IGDTTIPAGRR LLLYGSANRDER+YG DAAELDV R PRNILTFSHG HHCLGAAAAR Sbjct 311 IIGDTTIPAGRRALLLYGSANRDEREYGNDAAELDVLRKPRNILTFSHGNHHCLGAAAAR 370 Query 362 MQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 MQ R+AL ELL R PDFEV + W+ GSYVRRPL+VP RV Sbjct 371 MQSRIALEELLTRIPDFEVDLDGVTWADGSYVRRPLTVPIRV 412 >gi|333989863|ref|YP_004522477.1| cytochrome P450 [Mycobacterium sp. JDM601] gi|333485831|gb|AEF35223.1| cytochrome P450 130A4 Cyp130A4 [Mycobacterium sp. JDM601] Length=403 Score = 594 bits (1531), Expect = 9e-168, Method: Compositional matrix adjust. Identities = 289/394 (74%), Positives = 324/394 (83%), Gaps = 0/394 (0%) Query 8 EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSS 67 +F AETWPNP+PMY ALR+HDPVH V+P P+ DYYVLSRHADVW+AA DH+TFSS Sbjct 6 KFVPCNAETWPNPYPMYAALREHDPVHRVIPDGHPDQDYYVLSRHADVWAAAADHETFSS 65 Query 68 AQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVER 127 A+GLT+NY +LEMIGL D PPMVMQDPP HTEFRKLV+R FTP V+ +E VR+FVVER Sbjct 66 AKGLTINYNDLEMIGLADNPPMVMQDPPRHTEFRKLVARAFTPAHVKRLESQVREFVVER 125 Query 128 LEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGAL 187 +E+LRA G GDIVTELFKPLPSMVVAH+LGVP+ D QFD WT AIVAA + A Sbjct 126 IERLRAAGSGDIVTELFKPLPSMVVAHFLGVPQADRAQFDRWTDAIVAATVSEDGVASAG 185 Query 188 DAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDT 247 DAV MMAYF+GLIERRRT+ +D ISHLVAAG+GA GD AG +ILAF FTMVTGGNDT Sbjct 186 DAVVEMMAYFSGLIERRRTDQEEDTISHLVAAGMGAPGDDAGIFAILAFAFTMVTGGNDT 245 Query 248 VTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTT 307 TGMLGGS LLHR PDQRRLL+DDP I +AVEELLR+TSPVQGLART TRDVT+GDTT Sbjct 246 TTGMLGGSAQLLHRHPDQRRLLIDDPSLIHEAVEELLRMTSPVQGLARTATRDVTMGDTT 305 Query 308 IPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVA 367 IPAGRR LLLYGSANRDE+Q+GP A ELDV R PR ILTF +GAHHC+G AARMQ RVA Sbjct 306 IPAGRRALLLYGSANRDEQQFGPTAGELDVLRKPRQILTFGYGAHHCIGNQAARMQARVA 365 Query 368 LTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF 401 L ELLARCPDF V E+ I W+GG+YVRRPLSVPF Sbjct 366 LEELLARCPDFTVDEAGIRWAGGAYVRRPLSVPF 399 >gi|226365193|ref|YP_002782976.1| cytochrome P450 [Rhodococcus opacus B4] gi|226243683|dbj|BAH54031.1| cytochrome P450 [Rhodococcus opacus B4] Length=412 Score = 562 bits (1449), Expect = 3e-158, Method: Compositional matrix adjust. Identities = 281/399 (71%), Positives = 316/399 (80%), Gaps = 1/399 (0%) Query 4 VMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQ 63 V S F + ++W PW MY LRDHDPVHHVVP P+ DY+VLSRHADV++AARD + Sbjct 11 VSSVSFVPRSGQSWRAPWQMYADLRDHDPVHHVVPADAPDNDYWVLSRHADVYAAARDAE 70 Query 64 TFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKF 123 TFSSA GLT YGELE IGL D PP+VM DPP HT FR+LVS+GFTPRQV VEP VR F Sbjct 71 TFSSAAGLTTTYGELEKIGLQDNPPLVMLDPPDHTAFRRLVSKGFTPRQVTAVEPDVRAF 130 Query 124 VVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGAT 183 VVERL++LR G GD+V ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAANA G T Sbjct 131 VVERLDRLREAGEGDVVKELFKPLPSMVVAHYLGVPEADRAQFDGWTEAIVAANA-QGDT 189 Query 184 TGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTG 243 A AV +M YFT LIERRRT+P DD +SHLVA+G+GADGD AG LSIL F FTMVTG Sbjct 190 LQASGAVTDLMGYFTTLIERRRTDPGDDTVSHLVASGMGADGDVAGLLSILGFAFTMVTG 249 Query 244 GNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTI 303 GNDT TGMLGG++ LL +QRR L+D PE I DAVEELLRLTSPVQGLARTTTRDV I Sbjct 250 GNDTTTGMLGGAVQLLTHHREQRRELIDQPELIGDAVEELLRLTSPVQGLARTTTRDVEI 309 Query 304 GDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQ 363 T +PAGR+V LLYGSANRD R++GPDA +LDV R P+ ILTFSHGAHHCLGAAAARMQ Sbjct 310 AGTVVPAGRKVFLLYGSANRDPRRFGPDAEDLDVRRGPKQILTFSHGAHHCLGAAAARMQ 369 Query 364 CRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFR 402 R+AL ELLARCPDF V +V++ G+YVRRP SVPFR Sbjct 370 ARIALEELLARCPDFTVDIDAVVYAEGNYVRRPTSVPFR 408 >gi|111022684|ref|YP_705656.1| cytochrome P450 [Rhodococcus jostii RHA1] gi|110822214|gb|ABG97498.1| cytochrome P450 CYP130 [Rhodococcus jostii RHA1] Length=415 Score = 561 bits (1446), Expect = 6e-158, Method: Compositional matrix adjust. Identities = 280/400 (70%), Positives = 314/400 (79%), Gaps = 1/400 (0%) Query 4 VMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQ 63 V S F + ++W PW MY LRDHDPVHHVVP P DY+VLSRHADV++AARD + Sbjct 14 VSSVSFVPRSGQSWRAPWQMYAGLRDHDPVHHVVPEDAPGNDYWVLSRHADVYAAARDPE 73 Query 64 TFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKF 123 TFSSA GLT YGELE IGL D PP+VM DPP HT FR+LVS+GFTPRQV VEP VR F Sbjct 74 TFSSAAGLTTTYGELEKIGLQDNPPLVMLDPPDHTAFRRLVSKGFTPRQVTAVEPNVRAF 133 Query 124 VVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGAT 183 VVER+E+LR G GD+V ELFKPLPSMVVAHYLGVP+ED QFDGWT+AIVAANA G T Sbjct 134 VVERIERLREAGAGDVVKELFKPLPSMVVAHYLGVPDEDRAQFDGWTEAIVAANA-QGDT 192 Query 184 TGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTG 243 A AV +M YFTGLIERRRT+P DD ISHLVA G+GADGD G LSIL F FTMVTG Sbjct 193 LQATGAVTELMGYFTGLIERRRTDPGDDTISHLVAGGMGADGDITGLLSILGFAFTMVTG 252 Query 244 GNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTI 303 GNDT TGMLGG++ LL DQRR L++ PE + DAVEELLRLT+PVQGLART TRDV I Sbjct 253 GNDTTTGMLGGAVQLLTEHRDQRRDLIEHPELVRDAVEELLRLTAPVQGLARTVTRDVEI 312 Query 304 GDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQ 363 T +P GR+VLLLYGSANRD R++GPDA LDV R P+ ILTFSHGAHHCLGAAAARMQ Sbjct 313 EGTVVPEGRKVLLLYGSANRDPRRFGPDAEVLDVRRSPKQILTFSHGAHHCLGAAAARMQ 372 Query 364 CRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 R+AL ELLARCPDF V +V++ G+YVRRP SVPFRV Sbjct 373 ARIALEELLARCPDFTVDIDAVVYADGNYVRRPTSVPFRV 412 >gi|312140383|ref|YP_004007719.1| cytochrome p450 monooxygenase [Rhodococcus equi 103S] gi|311889722|emb|CBH49039.1| cytochrome P450 monooxygenase [Rhodococcus equi 103S] Length=410 Score = 553 bits (1424), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 282/409 (69%), Positives = 321/409 (79%), Gaps = 8/409 (1%) Query 1 MTSVMSHEFQLA--TAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ MS + + E+W +PW MY ALRDHDPVHHVVP P+ DY+VL+RH DV++A Sbjct 1 MTTTMSGKASYVPRSGESWRDPWGMYAALRDHDPVHHVVPDGSPQDDYWVLTRHEDVYTA 60 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARD +TFSSA+GLT+ YGEL+ IGL D PP+VM DPPVHT+FR+LV+RGFTPRQVE VEP Sbjct 61 ARDAETFSSAEGLTMTYGELDKIGLRDNPPLVMLDPPVHTQFRRLVARGFTPRQVEAVEP 120 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FVVERLE LRA G GDIVT LFKPLPSMVVAHYLGVP ED +FDGWT AIVAANA Sbjct 121 EVRRFVVERLEGLRAAGEGDIVTALFKPLPSMVVAHYLGVPPEDRGRFDGWTDAIVAANA 180 Query 179 VDGATTGALDAVGSMMAYFTGLIERRRTEP-----ADDAISHLVAAGVGADGDTAGTLSI 233 G A AV +M YF GLIERR+ E DD ISHLVAAG+GADGD +G LSI Sbjct 181 T-GDPLAAQTAVVELMTYFGGLIERRKAEAEAGNAGDDTISHLVAAGIGADGDVSGLLSI 239 Query 234 LAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGL 293 L F FTMVTGGNDT TGMLGG++ LL +R DQR LLL DP IP A+EELLRLTSPVQGL Sbjct 240 LGFAFTMVTGGNDTTTGMLGGAVQLLTQRRDQRDLLLADPGLIPGAIEELLRLTSPVQGL 299 Query 294 ARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHH 353 ARTTT DVTI D TIPAGR+VLL+YGSANRD R +G +A ELDV R P+ I+TFSHG HH Sbjct 300 ARTTTCDVTIDDATIPAGRKVLLVYGSANRDPRAFGENAEELDVRRNPKQIMTFSHGNHH 359 Query 354 CLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFR 402 CLGAAAARMQ RVAL ELLARCPDF+V + ++ G+YVRRP VPFR Sbjct 360 CLGAAAARMQARVALEELLARCPDFDVDIDGVEYAAGNYVRRPTHVPFR 408 >gi|325676007|ref|ZP_08155690.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707] gi|325553245|gb|EGD22924.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707] Length=410 Score = 552 bits (1422), Expect = 5e-155, Method: Compositional matrix adjust. Identities = 282/409 (69%), Positives = 321/409 (79%), Gaps = 8/409 (1%) Query 1 MTSVMS--HEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ MS + + E+W +PW MY ALRDHDPVHHVVP P+ DY+VL+RH DV++A Sbjct 1 MTTTMSGTASYVPRSGESWRDPWGMYAALRDHDPVHHVVPDGSPQDDYWVLTRHEDVYTA 60 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARD +TFSSA+GLT+ YGEL+ IGL D PP+VM DPPVHT+FR+LV+RGFTPRQVE VEP Sbjct 61 ARDAETFSSAEGLTMTYGELDKIGLRDNPPLVMLDPPVHTQFRRLVARGFTPRQVEAVEP 120 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FVVERLE LRA G GDIVT LFKPLPSMVVAHYLGVP ED +FDGWT AIVAANA Sbjct 121 EVRRFVVERLEGLRAAGEGDIVTALFKPLPSMVVAHYLGVPPEDRGRFDGWTDAIVAANA 180 Query 179 VDGATTGALDAVGSMMAYFTGLIERRRTEP-----ADDAISHLVAAGVGADGDTAGTLSI 233 G A AV +M YF GLIERR+ E DD ISHLVAAG+GADGD +G LSI Sbjct 181 T-GDPLAAQTAVVELMTYFGGLIERRKAEAEAGNAGDDTISHLVAAGIGADGDVSGLLSI 239 Query 234 LAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGL 293 L F FTMVTGGNDT TGMLGG++ LL +R DQR LLL DP IP A+EELLRLTSPVQGL Sbjct 240 LGFAFTMVTGGNDTTTGMLGGAVQLLTQRRDQRDLLLADPGLIPGAIEELLRLTSPVQGL 299 Query 294 ARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHH 353 ARTTT DVTI D TIPAGR+VLL+YGSANRD R +G +A ELDV R P+ I+TFSHG HH Sbjct 300 ARTTTCDVTIDDATIPAGRKVLLVYGSANRDPRAFGENAEELDVRRNPKQIMTFSHGNHH 359 Query 354 CLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFR 402 CLGAAAARMQ RVAL ELLARCPDF+V + ++ G+YVRRP VPFR Sbjct 360 CLGAAAARMQARVALEELLARCPDFDVDIDGVEYAAGNYVRRPTHVPFR 408 >gi|229494501|ref|ZP_04388264.1| putative cytochrome P450 123 [Rhodococcus erythropolis SK121] gi|229318863|gb|EEN84721.1| putative cytochrome P450 123 [Rhodococcus erythropolis SK121] Length=417 Score = 540 bits (1391), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 272/409 (67%), Positives = 320/409 (79%), Gaps = 5/409 (1%) Query 1 MTSVMSHE--FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ +SH F +T E+W +PW MY ALR++DPVH+VVP P+ DY+VL+RH DV++A Sbjct 7 MTTSVSHSPRFVPSTGESWRSPWAMYDALRENDPVHNVVPEAAPQDDYWVLTRHEDVYNA 66 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARD++T+SSA+GLT YGELE IG+ D PP VMQDPPV +EFR++VS+GFTPRQV VEP Sbjct 67 ARDYETYSSAKGLTTVYGELEQIGMQDNPPFVMQDPPVQSEFRRMVSKGFTPRQVSAVEP 126 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FVVER+E L+A G GDIV ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAAN+ Sbjct 127 MVREFVVERIEALKARGSGDIVVELFKPLPSMVVAHYLGVPESDRDQFDGWTEAIVAANS 186 Query 179 VDGATTGALDAVG---SMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILA 235 G A A +M YF LIERR+ EP DD ISHL+AAG+G DGD +G LSIL Sbjct 187 AGGVAAAATTAQAATGELMMYFASLIERRKVEPGDDTISHLLAAGLGEDGDMSGLLSILG 246 Query 236 FTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLAR 295 F FTMV GGNDT TGMLGGS +L R DQR++LLDDP I DAV+ELLRLTSPVQGLAR Sbjct 247 FAFTMVAGGNDTTTGMLGGSAAMLTERLDQRQILLDDPALITDAVDELLRLTSPVQGLAR 306 Query 296 TTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCL 355 TTTRDV +G IPAGR+VLL+YG+ANRD +YGPDAAELDV R P+ ILTFSHGAHHCL Sbjct 307 TTTRDVALGGKVIPAGRKVLLMYGAANRDPEKYGPDAAELDVLRRPQKILTFSHGAHHCL 366 Query 356 GAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVT 404 GA+AARMQ RVAL ELL+R PDF V + ++ G+YVRRPLS P VT Sbjct 367 GASAARMQARVALEELLSRIPDFHVDIDAMQYAPGNYVRRPLSAPMSVT 415 >gi|226304632|ref|YP_002764590.1| cytochrome P450 [Rhodococcus erythropolis PR4] gi|226183747|dbj|BAH31851.1| cytochrome P450 [Rhodococcus erythropolis PR4] Length=411 Score = 537 bits (1384), Expect = 1e-150, Method: Compositional matrix adjust. Identities = 269/408 (66%), Positives = 320/408 (79%), Gaps = 5/408 (1%) Query 1 MTSVMSHE--FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSA 58 MT+ +SH F +T E+W +PW MY ALR++DPVH+VVP P+ DY+VL+RH DV++A Sbjct 1 MTTSVSHSPRFVPSTGESWRSPWAMYDALRENDPVHNVVPEASPQDDYWVLTRHEDVYNA 60 Query 59 ARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEP 118 ARD++T+SSA+GLT YGELE IG+ D PP VMQDPPV +EFR++VS+GFTPRQV VEP Sbjct 61 ARDYETYSSAKGLTTVYGELEQIGMQDNPPFVMQDPPVQSEFRRMVSKGFTPRQVSAVEP 120 Query 119 TVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA 178 VR+FVVER+E L+A G GDIV ELFKPLPSMVVAHYLGVPE D QFDGWT+AIVAAN+ Sbjct 121 MVREFVVERIEALKARGSGDIVVELFKPLPSMVVAHYLGVPESDRDQFDGWTEAIVAANS 180 Query 179 VDGATTGALDAVG---SMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILA 235 G A A +M YF LIERR+ EP DD ISHL+AAG+G DGD +G LSIL Sbjct 181 AGGVAAAATTAQAATGELMMYFASLIERRKVEPGDDTISHLLAAGLGEDGDMSGLLSILG 240 Query 236 FTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLAR 295 F FTMV GGNDT TGMLGGS+ +L R DQR++LLDDP I DAV+ELLRLTSPVQGLAR Sbjct 241 FAFTMVAGGNDTTTGMLGGSVAMLTERLDQRQILLDDPALITDAVDELLRLTSPVQGLAR 300 Query 296 TTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCL 355 TTTRDV +G IPAGR+VLL+YG+ANRD +YGPDAAELDV R P+ ILTFSHGAHHCL Sbjct 301 TTTRDVALGGKVIPAGRKVLLMYGAANRDPEKYGPDAAELDVLRRPQKILTFSHGAHHCL 360 Query 356 GAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 GA+AARMQ RVAL ELL+R PDF + + ++ G+YVRRPL+ P V Sbjct 361 GASAARMQARVALEELLSRIPDFHIDIEAMQYAPGNYVRRPLTAPMSV 408 >gi|296179474|gb|ADG96480.1| cytochrome P450 [Gordonia cholesterolivorans] Length=407 Score = 535 bits (1378), Expect = 5e-150, Method: Compositional matrix adjust. Identities = 272/405 (68%), Positives = 308/405 (77%), Gaps = 4/405 (0%) Query 1 MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR 60 M + +S EF L + +W +P+ MY LRD DPVHHVVP P DYYVL+RHADV +AAR Sbjct 1 MKNDLSPEFTLRSGPSWRDPFEMYALLRDCDPVHHVVPEGDPAADYYVLTRHADVMAAAR 60 Query 61 DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV 120 D +TFSSA+GLTV YGELE IGL D PPMVMQDPP HT FR+LV+RGFTPRQV T+EP V Sbjct 61 DWETFSSARGLTVAYGELESIGLQDNPPMVMQDPPRHTAFRRLVARGFTPRQVTTLEPEV 120 Query 121 RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANA-- 178 R+FV+ERL L + GGGDI +LFKPLPSMVVAHYLGVPE D QFD WT AIVAAN Sbjct 121 REFVIERLADLASRGGGDIAADLFKPLPSMVVAHYLGVPESDRGQFDAWTDAIVAANPGA 180 Query 179 -VDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGAD-GDTAGTLSILAF 236 + A A +AV +MAYF LIE R+ P DD +SHLVAAG+ D D +G LS+LAF Sbjct 181 DMASAVESASEAVMGLMAYFADLIEFRKRSPGDDTVSHLVAAGLTDDPADQSGVLSVLAF 240 Query 237 TFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLART 296 FTMV GGNDT TGMLGGS LL PDQR +L +PE +P AV ELLRLTSPVQGLART Sbjct 241 AFTMVAGGNDTTTGMLGGSSALLTMHPDQRAILRREPELLPSAVNELLRLTSPVQGLART 300 Query 297 TTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLG 356 TRDV + + TIPAGR+VLL Y SANRDER YG DAA+LDV R P NILTFSHG+HHCLG Sbjct 301 ATRDVEVEEVTIPAGRKVLLCYASANRDERVYGEDAADLDVRRDPANILTFSHGSHHCLG 360 Query 357 AAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF 401 AAAARMQ RVAL ELLARCPDF V I W+ G+YVRRP+SVPF Sbjct 361 AAAARMQARVALEELLARCPDFHVDVDGIEWASGNYVRRPVSVPF 405 >gi|326381886|ref|ZP_08203579.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395] gi|326199312|gb|EGD56493.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395] Length=404 Score = 531 bits (1367), Expect = 1e-148, Method: Compositional matrix adjust. Identities = 279/404 (70%), Positives = 308/404 (77%), Gaps = 5/404 (1%) Query 5 MSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQT 64 MS EF L + TW +P+ MY LR +DPVHHVVP + P DYYVLSRHADV +AARD +T Sbjct 1 MSPEFTLRSGSTWRDPFGMYAQLRAYDPVHHVVPERDPSSDYYVLSRHADVMAAARDWET 60 Query 65 FSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFV 124 FSSAQGLTV YGELE IGL PPMVMQDPP HT+FR+LV+RGFTPRQV T+EP VR+FV Sbjct 61 FSSAQGLTVAYGELEKIGLQANPPMVMQDPPAHTDFRRLVARGFTPRQVTTLEPKVRQFV 120 Query 125 VERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAAN---AVDG 181 VERLE L A G GDI ELFKPLPSMVVAHYLGVP+ D +QFDGWT AIVAAN + Sbjct 121 VERLEDLVARGSGDIAAELFKPLPSMVVAHYLGVPDSDRSQFDGWTDAIVAANPGADLSA 180 Query 182 ATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGAD--GDTAGTLSILAFTFT 239 A T A DAV +MAYF+ LIE RR P DD +SHLVAAGV D G+ G LS+LAF FT Sbjct 181 AATTAADAVVGLMAYFSELIEYRRRNPGDDTVSHLVAAGVADDPEGNPGGVLSVLAFAFT 240 Query 240 MVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTR 299 MV GGNDT TGMLGGS LL DQR +LL +PE + AV ELLRLTSPVQGL RTTTR Sbjct 241 MVAGGNDTTTGMLGGSSALLTVERDQREILLREPELLAVAVNELLRLTSPVQGLTRTTTR 300 Query 300 DVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAA 359 DV I T+PAGR+VLL Y SANRDER YG DA LDV R P NILTFSHG+HHCLGAAA Sbjct 301 DVEIEGVTVPAGRKVLLCYASANRDERMYGEDADRLDVRRDPANILTFSHGSHHCLGAAA 360 Query 360 ARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 ARMQ RVAL ELLARCP FEV I W+ G+YVRRP+SVPF V Sbjct 361 ARMQARVALEELLARCPGFEVDVDGIEWATGNYVRRPVSVPFSV 404 >gi|296141452|ref|YP_003648695.1| cytochrome P450 [Tsukamurella paurometabola DSM 20162] gi|296029586|gb|ADG80356.1| cytochrome P450 [Tsukamurella paurometabola DSM 20162] Length=403 Score = 521 bits (1343), Expect = 6e-146, Method: Compositional matrix adjust. Identities = 271/404 (68%), Positives = 298/404 (74%), Gaps = 8/404 (1%) Query 5 MSHE-FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQ 63 MSH F +A++W NPWPMYRALR H PVHHV DYYVLSRHADV +A R+ Sbjct 1 MSHPVFAPCSAQSWRNPWPMYRALRTHSPVHHV--DNGDGADYYVLSRHADVAAALREPA 58 Query 64 TFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKF 123 TFSSA GLT YGELE GL D PPMVMQDPP HT+FR+LVSRGFTPRQV +EP VR F Sbjct 59 TFSSATGLTTVYGELERTGLQDNPPMVMQDPPNHTQFRRLVSRGFTPRQVSAIEPAVRDF 118 Query 124 VVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGAT 183 VV R+E+LRA GGGDIV LFKPLPSMVVAHYLGVPEED +FD WT+ IV A A G Sbjct 119 VVTRIERLRAEGGGDIVASLFKPLPSMVVAHYLGVPEEDRPRFDDWTERIVGAAAEAGTD 178 Query 184 TGALD-----AVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTF 238 A+ A+G +M YF L++RRR EP DD +SHLVAAG GADGDTAG LSIL F F Sbjct 179 IAAMGPEVATAIGELMGYFGELVQRRRREPGDDTVSHLVAAGYGADGDTAGLLSILGFAF 238 Query 239 TMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTT 298 TMVTGGNDT TGMLGG+ LL R DQ RLL DP IPDAVEE LRLTSPVQGLART T Sbjct 239 TMVTGGNDTTTGMLGGATELLARHRDQWRLLAGDPGLIPDAVEEFLRLTSPVQGLARTVT 298 Query 299 RDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAA 358 RD TI IPAGR+ LLLY SANRDER +G + ELDVTR PR ILTF+ G HHCLGAA Sbjct 299 RDTTIEGVCIPAGRKALLLYASANRDERVFGTRSEELDVTRRPREILTFAQGNHHCLGAA 358 Query 359 AARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFR 402 AARMQ RVAL ELL R PD +V I W+ G+YVRRPLS+ R Sbjct 359 AARMQSRVALHELLTRLPDLDVDPDSITWAPGNYVRRPLSLQVR 402 >gi|311744597|ref|ZP_07718396.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] gi|311312080|gb|EFQ81998.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] Length=410 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 260/395 (66%), Positives = 297/395 (76%), Gaps = 11/395 (2%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 F +++TW +P+ MY LR HDPVHHV DY+VL+RHADV++A RDH+TFSSA Sbjct 23 FVPGSSDTWADPFGMYAELRTHDPVHHVA-----GGDYWVLTRHADVFAAVRDHETFSSA 77 Query 69 QGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERL 128 +GLT YGEL+ IG+ D PPMVM DPP HTEFR+LVSRGFTPR VE VEP VR FV ERL Sbjct 78 EGLTTTYGELDAIGMRDNPPMVMTDPPSHTEFRRLVSRGFTPRHVEAVEPAVRAFVTERL 137 Query 129 EKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALD 188 E + + GGGDIV LFKPLPSMVVAHYLGVP D +FD WT+AIVAANA G G D Sbjct 138 ESIISAGGGDIVELLFKPLPSMVVAHYLGVPPTDHERFDRWTEAIVAANAT-GDPAGVAD 196 Query 189 AVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTV 248 AVG ++ YFT LIE RR PADD +SHLVAAG D AG L +LAFTFTMVTGGNDT Sbjct 197 AVGDLLGYFTELIEHRRDHPADDTVSHLVAAGEA--DDDAGILRVLAFTFTMVTGGNDTT 254 Query 249 TGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTI 308 TG+LGG++ LL RPDQR + LDD VEELLRLTSPVQGL RTTTRDVT+ DTTI Sbjct 255 TGLLGGAVQLLAARPDQRNIALDDARAT---VEELLRLTSPVQGLCRTTTRDVTLHDTTI 311 Query 309 PAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVAL 368 P+GR+VLL YG+ANRD YGPDA +LDVTR PR++LTF+HGAHHCLGAAAARM RV L Sbjct 312 PSGRKVLLCYGAANRDVDAYGPDAEQLDVTRDPRHVLTFAHGAHHCLGAAAARMMGRVTL 371 Query 369 TELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRV 403 ELL R PDF V + W+ G+YVRRP VPF V Sbjct 372 EELLTRIPDFAVDHDAVTWADGAYVRRPTRVPFTV 406 >gi|326329198|ref|ZP_08195525.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] gi|325952993|gb|EGD45006.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1] Length=397 Score = 474 bits (1219), Expect = 1e-131, Method: Compositional matrix adjust. Identities = 262/408 (65%), Positives = 299/408 (74%), Gaps = 14/408 (3%) Query 1 MTSVMSH---EFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWS 57 MTS +SH + T +W +PWPMY ALR+HDPVHHVV DY+VL+RH DV+S Sbjct 1 MTSDVSHGIAAYVPPTRPSWADPWPMYAALREHDPVHHVV-----RSDYWVLTRHDDVFS 55 Query 58 AARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVE 117 A RDH+TFSS GLT + ELE IGL + PPMVM DPP HT FRKLV+RGFTP+QVE V Sbjct 56 AVRDHETFSSTGGLTTAHDELERIGLAENPPMVMTDPPAHTAFRKLVNRGFTPKQVEDVT 115 Query 118 PTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAAN 177 P V +FV ER++ +RA GGGDIV ELFKPLPSMVVAHYLGVPEEDW +FD WT AIV AN Sbjct 116 PRVTRFVSERIDAIRAAGGGDIVAELFKPLPSMVVAHYLGVPEEDWGRFDVWTDAIVTAN 175 Query 178 AVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFT 237 A GA A +M YF LIERRR +P DD +SHLVAAG D AG L +LAF Sbjct 176 AAQDEAIGAG-AAAELMGYFAELIERRRRDPGDDTVSHLVAAGEA--DDDAGLLRVLAFA 232 Query 238 FTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTT 297 FTMV GGNDT TG+LGG +PLL RPDQR L L D +P AVEELLRLTSPVQGLARTT Sbjct 233 FTMVAGGNDTTTGLLGGGLPLLAVRPDQRELALQD---VPAAVEELLRLTSPVQGLARTT 289 Query 298 TRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGA 357 TRDVT+ TIPAG++VLL Y +ANRD R +G DA ELDVTR PR ILTF+HGAHHCLGA Sbjct 290 TRDVTLHGVTIPAGKKVLLCYAAANRDPRVFGADAEELDVTRNPRQILTFAHGAHHCLGA 349 Query 358 AAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS 405 AAARM RV LTE+L R P F V + W+ GSYVRRP+S+ VT+ Sbjct 350 AAARMMGRVTLTEILTRMPSFTVDHDSVAWAPGSYVRRPVSLRVEVTA 397 >gi|262200984|ref|YP_003272192.1| cytochrome P450 CYP124E1 [Gordonia bronchialis DSM 43247] gi|262084331|gb|ACY20299.1| cytochrome P450 CYP124E1 [Gordonia bronchialis DSM 43247] Length=414 Score = 462 bits (1190), Expect = 4e-128, Method: Compositional matrix adjust. Identities = 261/412 (64%), Positives = 293/412 (72%), Gaps = 16/412 (3%) Query 1 MTSVMSHE--FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYD---YYVLSRHADV 55 MTS SH F L + TW NP+ MY LR PVH V D Y+VL+RHADV Sbjct 1 MTSTTSHAPVFTLRSGATWANPFGMYARLRSAAPVHRVATGAASASDPGEYWVLTRHADV 60 Query 56 WSAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVET 115 +AA D TFSSA GLTV YGEL IG+ D PPMVM DPP HT FR+LV+RGFTPRQV Sbjct 61 LAAASDPSTFSSADGLTVTYGELAAIGMTDNPPMVMTDPPAHTAFRRLVARGFTPRQVSA 120 Query 116 VEPTVRKFVVERLEKL--RANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAI 173 +EP +R FV ERL+++ ++G DIV ELFKPLPSMVVAHYLGVPE D QFDGWT AI Sbjct 121 LEPQIRDFVRERLDRIDGASDGPADIVGELFKPLPSMVVAHYLGVPESDRAQFDGWTDAI 180 Query 174 VAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSI 233 V A+ D G A M+ YF LIE RR PADD +SHLVAAG+ AD D AG LS+ Sbjct 181 VGASP-DSPDAGP--ATLDMLGYFGRLIEYRRDHPADDTVSHLVAAGI-ADED-AGVLSV 235 Query 234 LAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGL 293 LAFTFTMV GGNDT TGMLGGS+ LLHR PDQR LLDDP I DAV+E LRLTSPVQ L Sbjct 236 LAFTFTMVAGGNDTTTGMLGGSIELLHRYPDQRARLLDDPALIGDAVDEFLRLTSPVQNL 295 Query 294 ARTTTRDVTI----GDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSH 349 ARTTTR VT+ G TIPA R+VLL Y +ANRD + +GPDA LDV R PRNILTFSH Sbjct 296 ARTTTRAVTLAGADGPVTIPAARKVLLCYAAANRDPQAFGPDAEHLDVGRRPRNILTFSH 355 Query 350 GAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF 401 GAHHCLGAAAAR+ RV LTELL+R PDF V + I W+ G+YVRRP VPF Sbjct 356 GAHHCLGAAAARLAARVTLTELLSRYPDFAVDVAGIRWAEGNYVRRPTYVPF 407 >gi|119718837|ref|YP_925802.1| RelA/SpoT domain-containing protein [Nocardioides sp. JS614] gi|119539498|gb|ABL84115.1| RelA/SpoT domain protein [Nocardioides sp. JS614] Length=1046 Score = 410 bits (1054), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 210/297 (71%), Positives = 237/297 (80%), Gaps = 3/297 (1%) Query 91 MQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSM 150 M DPP HT FRKLV+RGFTPRQV T+EP VR FVVERLE+LRA GGGD+V LFKPLP+M Sbjct 1 MLDPPEHTAFRKLVARGFTPRQVATLEPMVRAFVVERLERLRAEGGGDVVETLFKPLPTM 60 Query 151 VVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPAD 210 VVAHYLGVPE+ +F WT AIV+A++ G GA +A+G +MAYFT LI+RRR EP D Sbjct 61 VVAHYLGVPEDGRERFAAWTHAIVSASSA-GEVLGAAEALGELMAYFTELIDRRRGEPGD 119 Query 211 DAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLL 270 D +SHLVAAGVG DT G LSILA+ FT+VTGGNDT TGMLGG++ LL DQRRLLL Sbjct 120 DTVSHLVAAGVG--DDTRGLLSILAYIFTVVTGGNDTTTGMLGGTVQLLEAARDQRRLLL 177 Query 271 DDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGP 330 DDP +PDAVEELLRLTSPVQGLARTTTRDV + T +P GRRVLLLYG+ANRD R+YGP Sbjct 178 DDPGLVPDAVEELLRLTSPVQGLARTTTRDVELHGTKVPEGRRVLLLYGAANRDPRRYGP 237 Query 331 DAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVW 387 DA ELDV R P ILTFS G+HHCLGAAAAR+Q RVAL ELLARCPDF V + W Sbjct 238 DADELDVRRRPTQILTFSQGSHHCLGAAAARLQARVALEELLARCPDFAVDLDGVEW 294 >gi|254774283|ref|ZP_05215799.1| hypothetical protein MaviaA2_06390 [Mycobacterium avium subsp. avium ATCC 25291] Length=189 Score = 341 bits (875), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 168/189 (89%), Positives = 177/189 (94%), Gaps = 0/189 (0%) Query 217 VAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGI 276 ++AGVGADGD AGTLS+LAFTFTMVTGGNDT TGMLGGSMPLLH+RPDQR+ L+D+PE I Sbjct 1 MSAGVGADGDIAGTLSVLAFTFTMVTGGNDTTTGMLGGSMPLLHQRPDQRQRLVDEPELI 60 Query 277 PDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELD 336 PDAVEELLRLTSPVQGLARTTTRDVTIG TTIPAGRRVLLLYGSANRDERQYGPDA ELD Sbjct 61 PDAVEELLRLTSPVQGLARTTTRDVTIGRTTIPAGRRVLLLYGSANRDERQYGPDAGELD 120 Query 337 VTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRP 396 V RCPRNILTFSHGAHHCLGAAAARMQ RVALTELLARCPDFEV ES IVW+GG+YVRRP Sbjct 121 VARCPRNILTFSHGAHHCLGAAAARMQSRVALTELLARCPDFEVDESGIVWAGGNYVRRP 180 Query 397 LSVPFRVTS 405 LSVP RV S Sbjct 181 LSVPIRVKS 189 >gi|333918653|ref|YP_004492234.1| cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] gi|333480874|gb|AEF39434.1| Cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] Length=255 Score = 335 bits (860), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 167/253 (67%), Positives = 192/253 (76%), Gaps = 1/253 (0%) Query 150 MVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPA 209 MVVAHYLGVPEED QFD WT AIV A A G T A A+ MM Y T LIERRR EP Sbjct 1 MVVAHYLGVPEEDRPQFDEWTHAIVGATAT-GENTAAEAAIADMMQYCTALIERRRVEPG 59 Query 210 DDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLL 269 DD I+HLVA+G+G GD AG LSIL F FTM++GGNDT TG LGG++ LL PD+RR L Sbjct 60 DDTIAHLVASGLGQKGDVAGMLSILGFAFTMISGGNDTTTGNLGGAVQLLEMFPDERRRL 119 Query 270 LDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYG 329 ++D + IPD+ E LRLTSPVQGLART TRDV TIPAGRRVLLLY SANRDER +G Sbjct 120 INDMDLIPDSANEFLRLTSPVQGLARTATRDVVYESATIPAGRRVLLLYASANRDERAFG 179 Query 330 PDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSG 389 PDA +LDVTR P+NILTFS G+HHCLGAAAARMQ ++AL ELLARCP+F + + ++ Sbjct 180 PDAGQLDVTRKPKNILTFSQGSHHCLGAAAARMQAQIALEELLARCPNFTIDIEGVRYAE 239 Query 390 GSYVRRPLSVPFR 402 G+YVR P SVPFR Sbjct 240 GNYVRWPTSVPFR 252 >gi|126437155|ref|YP_001072846.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126236955|gb|ABO00356.1| cytochrome P450 [Mycobacterium sp. JLS] Length=398 Score = 263 bits (671), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 157/368 (43%), Positives = 208/368 (57%), Gaps = 10/368 (2%) Query 14 AETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTV 73 A +P+P YR+LRD PV+ E +VLSRHADV +AA DH T+SS G+ Sbjct 13 ASILNDPYPTYRSLRDTAPVYRA-----EESHTWVLSRHADVQAAALDHGTYSSVDGIFP 67 Query 74 NYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKL-R 132 + IG P M++ DPP H + R LVSR FTPR+V ++ + + E E+L Sbjct 68 TPPGSDFIGSF-LPMMIVMDPPRHDQLRALVSRAFTPRRVAGLQGAITQMAAELFERLDE 126 Query 133 ANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGS 192 +G D VT+ LP+ V+A LG+P D QF W+ +V + G TT AL A S Sbjct 127 GSGSADFVTDFAAILPAAVIADLLGIPATDRDQFRLWSSQLVQVDVNHGQTTDALTAATS 186 Query 193 MMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGML 252 + AYFT + RR P +D +S L A V DG +L F ++ G +T T +L Sbjct 187 IYAYFTDFLADRRQTPREDMMSALANATV--DGIRLTDEEVLGFCALLLVAGYETTTNLL 244 Query 253 GGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGR 312 G S +L + RR L D + AVEELLR SP QGL+RT TRDVT+ DTT+ G Sbjct 245 GNSAVVLAQHRQTRRRLAADRTLLGPAVEELLRYDSPAQGLSRTLTRDVTLHDTTMRQGE 304 Query 313 RVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELL 372 +VLLL+GSANRDER + PD D+ R + + F G H CLGAA ARM+ R+AL LL Sbjct 305 KVLLLFGSANRDERAF-PDPDVFDIERTSEHQVAFGRGIHFCLGAALARMEARIALDALL 363 Query 373 ARCPDFEV 380 + PD+EV Sbjct 364 DKVPDWEV 371 >gi|119716393|ref|YP_923358.1| cytochrome P450 [Nocardioides sp. JS614] gi|119537054|gb|ABL81671.1| cytochrome P450 [Nocardioides sp. JS614] Length=392 Score = 259 bits (661), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 152/384 (40%), Positives = 218/384 (57%), Gaps = 9/384 (2%) Query 19 NPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGEL 78 +P+P+YR LRD+ P + P+ +VLSRH DVW A D T+SSA G+ + Sbjct 18 DPYPVYRELRDNAPAY-----WSPQASSWVLSRHQDVWGALADPTTYSSASGIFPTPPGV 72 Query 79 EMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGD 138 +M L P ++M DPP HT+ R+LVS+ FTPR++ +E + V L++ G D Sbjct 73 DMTELF-LPMLIMSDPPRHTQLRRLVSKAFTPRRIAGLEAHIETLVDGLLDEAPEAGAWD 131 Query 139 IVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFT 198 V+ PLP++V+A LGVP ED +F W+ ++ +N G LDA ++ YF+ Sbjct 132 FVSGFAGPLPAIVIADMLGVPSEDRDRFRTWSTTLIQSNPTRGEFGAGLDAASALYEYFS 191 Query 199 GLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPL 258 + RR P DD ++ LV A V DG+ +L F ++ G++T T +L S + Sbjct 192 AFLAERRAHPQDDLMTALVHAEV--DGEHLSEDELLGFCLLLLVAGHETTTNLLSNSAVV 249 Query 259 LHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLY 318 L + PD RR L D+P+ +P AVEELLR SPVQGLART TR V + + G VLLL+ Sbjct 250 LAQHPDSRRQLADNPKLVPAAVEELLRYDSPVQGLARTLTRQVDLHGQAMEPGDTVLLLF 309 Query 319 GSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDF 378 GSANRD++ + P+A D+ R P + F G H CLGA+ AR++ R+AL LLAR D+ Sbjct 310 GSANRDDQAF-PEADHFDIHRDPERQVAFGRGIHFCLGASLARLEARIALETLLARRRDW 368 Query 379 EVAESRIVWSGGSYVRRPLSVPFR 402 +V V +R S+P R Sbjct 369 DVDLDSAVRLRSGPIRGYSSLPLR 392 >gi|333921949|ref|YP_004495530.1| cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] gi|333484170|gb|AEF42730.1| Cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] Length=398 Score = 253 bits (645), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 155/391 (40%), Positives = 224/391 (58%), Gaps = 15/391 (3%) Query 19 NPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGEL 78 +P+P+Y+ LR+ PV+ E +++ LSR D+W+A +DH+ FSSA+G+ V G+ Sbjct 15 DPYPVYQVLREESPVY-----WNTEQEFWALSRFDDIWTATQDHRRFSSAEGIIV--GQD 67 Query 79 EMIGLHDTPPMVMQDPPV-HTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGG 137 G+ D PM++ P H+ RKLVSR FTPR++ +E ++R LE G Sbjct 68 LATGMVDLMPMMIMMDPPRHSALRKLVSRAFTPRRMAGMEDSIRATARGLLESFIERGEV 127 Query 138 DIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATT-GALDAVGSMMAY 196 D V E PLP++V+A LG+P ED QF W+ +V N D A+ ++A + Y Sbjct 128 DFVHEYAGPLPTIVIADMLGIPNEDRQQFREWSDRLVQVNPNDPASVEDGMNAALGLYDY 187 Query 197 FTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSM 256 FT ++ RR DD +S L+ A V DG+ +L F F ++ GN+T T ++ + Sbjct 188 FTPMLAARRANRKDDLMSALLDAEV--DGERLSEEELLGFCFMLLIAGNETTTNLISNTA 245 Query 257 PLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLL 316 +L RPD R + D +P AVEE LRL SPVQGLART T DV + T+ G +V++ Sbjct 246 QILSERPDTLRTIAADHSLLPAAVEEFLRLESPVQGLARTVTEDVELHGETMRTGSKVMM 305 Query 317 LYGSANRDERQYG-PDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARC 375 LYGSANRD+R++ P++ LD R L F HG H CLGAA AR++CRVA ELL+ Sbjct 306 LYGSANRDDREFADPESFILD--RKTERGLAFGHGPHFCLGAALARLECRVAYEELLSYV 363 Query 376 PDFEVAE-SRIVWSGGSYVRRPLSVPFRVTS 405 PDF + + + + SG + L + F TS Sbjct 364 PDFALTDGAERLLSGPVRGYKKLPMTFEPTS 394 >gi|296164721|ref|ZP_06847286.1| cytochrome P450 Cyp189A7 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899939|gb|EFG79380.1| cytochrome P450 Cyp189A7 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=412 Score = 253 bits (645), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 152/392 (39%), Positives = 220/392 (57%), Gaps = 18/392 (4%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 F E +P+PM++ LRD P+++ EYD+Y LSR ADV A D+ T+SSA Sbjct 22 FDPYDVELIADPYPMFKRLRDEAPLYY-----NSEYDFYALSRFADVNKAIIDYGTYSSA 76 Query 69 QGLTVNYGELEMIGLHDTPP---MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVV 125 +G+ +E+I + P ++ +DPP+H RKL+SR FTPR++ +EP +R+F Sbjct 77 RGVI-----MELIKANLEIPSGMLIFEDPPIHDVHRKLLSRMFTPRKIAALEPMIREFCA 131 Query 126 ERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTG 185 + L+ L +G D VT+L +P V++ LG+PEED A + G Sbjct 132 QALDPLVGSGRFDFVTDLGAIMPMKVISALLGIPEEDQEYIRDRGNAQLRTEP--GKPMS 189 Query 186 ALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTL---SILAFTFTMVT 242 A + S+ F I+ R P+DD ++ L+ + T L IL + + Sbjct 190 AAEHGLSVGEQFEAYIDWRADNPSDDIMTELLNVEFVDETGTTRRLRREEILVYLNVVAG 249 Query 243 GGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVT 302 GN+T T ++G + +L PDQRR L+++P IP A+EELLR P +AR TRDV+ Sbjct 250 AGNETTTRLIGWAGKVLAEHPDQRRELVENPGLIPQAIEELLRFEPPAPHMARYVTRDVS 309 Query 303 IGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARM 362 + D T+P G +L+L GSA RDERQ+GPDA E D+ R R LTFS GAH CLG+A AR+ Sbjct 310 LYDQTVPEGSVMLMLIGSACRDERQFGPDAGEFDIHRPARPHLTFSVGAHFCLGSALARL 369 Query 363 QCRVALTELLARCPDFEVAESRIVWSGGSYVR 394 + RVAL E+L R P++E + S S VR Sbjct 370 EGRVALEEILKRFPEWEPDLANATLSPTSSVR 401 >gi|120401342|ref|YP_951171.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119954160|gb|ABM11165.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=398 Score = 252 bits (644), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 158/368 (43%), Positives = 208/368 (57%), Gaps = 10/368 (2%) Query 14 AETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTV 73 A +P+P YR LRD PV+ E +VLSRHADV +AA DH T+SS G+ Sbjct 13 ASILNDPYPTYRLLRDVAPVYRA-----EESHTWVLSRHADVQAAALDHSTYSSVDGIFP 67 Query 74 NYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKL-R 132 + IG P M++ DPP H + R LVSR FTPR+V ++ T+ + E E+L Sbjct 68 TPPGSDFIGSF-LPMMIVMDPPRHDQLRALVSRAFTPRRVAGLQGTITQMAAELFERLDE 126 Query 133 ANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGS 192 +G D VT+ LP+ V+A LGVP D QF W+ +V + G TT AL A + Sbjct 127 GSGSADFVTDFAAILPAAVIADLLGVPATDRDQFRLWSSQLVQVDVNHGQTTDALAAAAA 186 Query 193 MMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGML 252 + AYFT + RR P +D +S L A V DG +L F ++ G +T T +L Sbjct 187 IYAYFTDFLADRRKNPREDLMSALANATV--DGIGLTDEEVLGFCALLLVAGYETTTNLL 244 Query 253 GGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGR 312 G S +L + RR L D + AVEELLR SP QGL+RT TRDVT+ DTT+ G Sbjct 245 GNSAVVLAQHRQTRRRLAADRTLLGPAVEELLRYDSPAQGLSRTLTRDVTLHDTTMRQGE 304 Query 313 RVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELL 372 +VLLL+GSANRDER + PD D+ R + + F G H CLGAA ARM+ R+AL LL Sbjct 305 KVLLLFGSANRDERAF-PDPDVFDIERTSEHQVAFGRGIHFCLGAALARMEARIALNALL 363 Query 373 ARCPDFEV 380 + PD+EV Sbjct 364 DKVPDWEV 371 >gi|311742017|ref|ZP_07715827.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] gi|311314510|gb|EFQ84417.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] Length=392 Score = 251 bits (642), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 149/366 (41%), Positives = 210/366 (58%), Gaps = 9/366 (2%) Query 15 ETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVN 74 E +P+P+YR LR H PV+ + + +VLSR+ DV A D T SSA G+ Sbjct 14 EVMADPYPVYRELRAHAPVY-----WSSQANCWVLSRYDDVCVALADPATHSSASGIFPT 68 Query 75 YGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRAN 134 ++M L P ++M DPP HT+ R LVS+ FTPR++ +EP + V + L+++ Sbjct 69 PPGVDMTDLF-LPMLIMSDPPRHTQLRHLVSKAFTPRRITELEPHIHSIVDDLLDQVPVA 127 Query 135 GGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMM 194 G D V+ PLP++V+A LGVP +D QF W+ ++ +N G LDA ++ Sbjct 128 GPWDFVSRFAGPLPAIVIADMLGVPRKDRDQFRNWSTTLIQSNPTRGEFGPGLDAAAALY 187 Query 195 AYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGG 254 YF+ + RR P DD ++ LV A V DG+ +L F ++ G++T T +L Sbjct 188 EYFSAFLTERRAHPRDDLMTALVQAEV--DGEQLTDDELLGFCLLLLVAGHETTTNLLSN 245 Query 255 SMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRV 314 S +L + PD RR L D+P+ IP AVEELLR SPVQGLART T+ V + + AG V Sbjct 246 SAVILAQHPDTRRQLADNPDLIPAAVEELLRYDSPVQGLARTLTQQVDLHGQPMKAGDTV 305 Query 315 LLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLAR 374 LLL+GSANRD+ DA D+ R P + F G H CLGA+ AR++ RVAL LLAR Sbjct 306 LLLFGSANRDDHAIT-DADHFDINRRPERQVAFGRGIHFCLGASLARLEARVALQALLAR 364 Query 375 CPDFEV 380 D++V Sbjct 365 HRDWDV 370 >gi|254818816|ref|ZP_05223817.1| cytochrome P450 [Mycobacterium intracellulare ATCC 13950] Length=401 Score = 251 bits (640), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 151/385 (40%), Positives = 219/385 (57%), Gaps = 24/385 (6%) Query 19 NPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGEL 78 +P+PM+ LR P+++ E+D+Y +SR+ADV A DH+T+SSA+G L Sbjct 21 DPYPMFARLRQEAPLYY-----NAEFDFYAVSRYADVSKALVDHETYSSARGAI-----L 70 Query 79 EMIGLHDTPP---MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANG 135 E+I + P ++ +DPP+H RKL+SR FTPR++ +EP +R F + L+ L +G Sbjct 71 ELIKANLEIPSGMLIFEDPPIHDVHRKLLSRMFTPRRIAALEPMIRDFCAQLLDPLVGSG 130 Query 136 GGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIV---AANAVDGATTGALDAVGS 192 D VT+L +P V++ LG+PE+D A + A +D A G +VG Sbjct 131 HFDFVTDLGAQMPMKVISMLLGIPEDDQEYIRDRGNAQLRTEAGKPMDAAQHGL--SVGE 188 Query 193 MMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS---ILAFTFTMVTGGNDTVT 249 F I+ R P+DD ++ L+ + LS IL + + GN+T T Sbjct 189 Q---FEAYIDWRAEHPSDDIMTELLNVEFVDETGVNRHLSREEILVYLNVVAGAGNETTT 245 Query 250 GMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIP 309 ++G S +L PDQRR LL++P IP A+EELLR P ++R TRDVT+ D T+P Sbjct 246 RLIGWSGKVLAEHPDQRRDLLENPALIPQAIEELLRYEPPAPHVSRYVTRDVTVHDQTVP 305 Query 310 AGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALT 369 G +++L GSA RDE Q+GPDA E ++ R R LTFS G H CLG+A AR++ RVAL Sbjct 306 EGSVMMMLIGSACRDEAQFGPDAGEFNIHRAVRPHLTFSMGTHFCLGSALARLEGRVALE 365 Query 370 ELLARCPDFEVAESRIVWSGGSYVR 394 E+L R P++EV S+ S S VR Sbjct 366 EILKRFPEWEVDLSKATLSPTSTVR 390 >gi|240173182|ref|ZP_04751840.1| cytochrome P450 189A7 Cyp189A7 [Mycobacterium kansasii ATCC 12478] Length=400 Score = 249 bits (636), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 152/395 (39%), Positives = 217/395 (55%), Gaps = 24/395 (6%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 F E +P+PM+R LRD P+++ ++D+Y LSR ADV A D+QTFSSA Sbjct 11 FDPYDVELNADPYPMFRRLRDEAPLYY-----NAQHDFYALSRFADVERAIVDYQTFSSA 65 Query 69 QGLTVNYGELEMIGLH-DTPP--MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVV 125 +G LE+I + D PP +V +DPP+H RKL+SR FTPR++ +EP +R+F Sbjct 66 RGAI-----LEIIKANIDIPPGVLVFEDPPIHNVHRKLLSRMFTPRKINDLEPKIREFCS 120 Query 126 ERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIV---AANAVDGA 182 L+ L G D V +L +P V+ LGVPEED + A + A + + Sbjct 121 RSLDPLVGTGRFDFVADLGAQMPMRVIGMLLGVPEEDQEAARDFANAQLRTEAGKPMKAS 180 Query 183 TTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTL---SILAFTFT 239 T G + +F I+ R PA+D ++ L+ + T L +L + Sbjct 181 TDGMVSG-----DFFARYIDWRAEHPANDIMTELLNVEFEDETGTVRRLRRDELLIYVSV 235 Query 240 MVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTR 299 + GN+T T ++G + +L PDQRR L+DDP IP AVEELLR P +AR TR Sbjct 236 VSGAGNETTTRLIGWAGKVLAEHPDQRRALVDDPSLIPQAVEELLRYEPPAPHVARYVTR 295 Query 300 DVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAA 359 DV +P G +++L G+ANRD RQ+ PD D+ R PR LTFS G H+CLG+A Sbjct 296 DVEYYGRQVPKGSVMMMLIGAANRDHRQFPPDGDVFDIRREPRQHLTFSVGTHYCLGSAL 355 Query 360 ARMQCRVALTELLARCPDFEVAESRIVWSGGSYVR 394 AR++ R+AL E+L R P+++V S+ S S VR Sbjct 356 ARLEGRIALEEILKRFPEWDVDLSQAKLSPTSTVR 390 >gi|342861362|ref|ZP_08718010.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342131262|gb|EGT84543.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=400 Score = 249 bits (635), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 151/384 (40%), Positives = 222/384 (58%), Gaps = 22/384 (5%) Query 19 NPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGEL 78 +P+PM+ LR+ P+++ EYD+Y +SR+ADV A DH+T+SSA+G L Sbjct 21 DPYPMFARLREEAPLYY-----NAEYDFYAVSRYADVSKALVDHETYSSARGAI-----L 70 Query 79 EMIGLH-DTPP--MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANG 135 E+I + + PP ++ +DPP+H RKL+SR FTPR++ +EP +R F + L+ L +G Sbjct 71 ELIKANLEIPPGMLIFEDPPIHDVHRKLLSRMFTPRRIAALEPMIRDFCAQLLDPLVGSG 130 Query 136 GGDIVTELFKPLPSMVVAHYLGVPEED--WTQFDGWTQAIVAANAVDGATTGALDAVGSM 193 D VT+L +P V++ LG+PE+D + + G Q A A L AVG Sbjct 131 RFDFVTDLGAQMPMKVISMLLGIPEDDQEYIRDRGNAQLRTEAGKPMSAAEHGL-AVGEQ 189 Query 194 MAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS---ILAFTFTMVTGGNDTVTG 250 F I+ R P+DD ++ L+ + T LS IL + + GN+T T Sbjct 190 ---FEAYIDWRGEHPSDDIMTELLNVEFVDETGTTRRLSREEILVYLNVVAGAGNETTTR 246 Query 251 MLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPA 310 ++G S +L PDQRR L+++P IP A+EELLR P ++R TRDVT+ D T+P Sbjct 247 LIGWSGKVLAEHPDQRRDLVENPALIPQAIEELLRYEPPAPHVSRYVTRDVTVHDQTVPE 306 Query 311 GRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTE 370 G +++L GSA RDE Q+G DA + ++ R R LTFS G H CLG+A AR++ RVAL E Sbjct 307 GSVMMMLIGSACRDEAQFGSDAGDFNIHRTVRPHLTFSMGTHFCLGSALARLEGRVALEE 366 Query 371 LLARCPDFEVAESRIVWSGGSYVR 394 +L R P++E+ + V S S VR Sbjct 367 ILKRFPEWEIDLTNAVLSPTSTVR 390 >gi|118466989|ref|YP_882170.1| cytochrome P450 [Mycobacterium avium 104] gi|118168276|gb|ABK69173.1| cytochrome P450 [Mycobacterium avium 104] Length=400 Score = 248 bits (632), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 148/382 (39%), Positives = 217/382 (57%), Gaps = 18/382 (4%) Query 19 NPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGEL 78 +P+PM+ LR+ P+++ EYD+Y +SR+ADV A DH+T+SSA+G L Sbjct 21 DPYPMFARLREEAPLYY-----NAEYDFYAVSRYADVSKALVDHETYSSARGAI-----L 70 Query 79 EMIGLH-DTPP--MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANG 135 E+I + D P ++ +DPP+H RKL+SR FTPR++ +EP +R F + L+ L G Sbjct 71 ELIKANLDIPSGMLIFEDPPIHDVHRKLLSRMFTPRRIAALEPMIRDFCAQCLDPLVGTG 130 Query 136 GGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMA 195 D VT+L +P V++ LG+PE+D A + A G A + S+ Sbjct 131 HFDFVTDLGAQMPMKVISMLLGIPEDDQEYIRDRGNAQLRTEA--GKPMKAAEQGLSVGE 188 Query 196 YFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLS---ILAFTFTMVTGGNDTVTGML 252 F I+ R P+DD ++ L+ + T L+ IL + + GN+T T ++ Sbjct 189 QFEAYIDWRAEHPSDDIMTELLNVEFVDETGTTRRLTREEILVYLNVVAGAGNETTTRLI 248 Query 253 GGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGR 312 G + +L PDQRR L+++P IP A+EELLR P ++R TRDV + D T+P G Sbjct 249 GWTGKVLAEHPDQRRDLVENPALIPQAIEELLRYEPPAPHVSRYVTRDVVVHDQTVPEGS 308 Query 313 RVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELL 372 +++L GSA RDE Q+G DA E ++ R R LTFS G H CLG+A AR++ RVAL E+L Sbjct 309 VMMMLIGSACRDEAQFGSDAGEFNIHRAVRPHLTFSMGTHFCLGSALARLEGRVALEEIL 368 Query 373 ARCPDFEVAESRIVWSGGSYVR 394 R P++EV SR S S VR Sbjct 369 KRFPEWEVDLSRATLSPTSTVR 390 >gi|108800798|ref|YP_640995.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119869938|ref|YP_939890.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108771217|gb|ABG09939.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119696027|gb|ABL93100.1| cytochrome P450 [Mycobacterium sp. KMS] Length=404 Score = 247 bits (631), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 143/398 (36%), Positives = 219/398 (56%), Gaps = 18/398 (4%) Query 9 FQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSA 68 F E +P+PM++ LR+ P+++ +YD+Y +SR+ DV A DH+TFSSA Sbjct 15 FDPYDVELNADPYPMFKRLREEAPLYY-----NTQYDFYAVSRYDDVCKALVDHETFSSA 69 Query 69 QGLTVNYGELEMIGLH-DTPP--MVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVV 125 +G + E+I + D PP ++ +DPP+H RKL++R FTPR++ +EP +R+F Sbjct 70 RGAII-----ELIKANIDIPPGTVIFEDPPIHDVHRKLLARMFTPRKINALEPKIREFCA 124 Query 126 ERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTG 185 + L+ L G D +T+ +P V++ LG+PE+D + A + A G Sbjct 125 QSLDPLVGAGRFDFITDFGAQMPMKVISSLLGIPEDDQEMIRDYGNAQLRTEA--GKPMS 182 Query 186 ALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTL---SILAFTFTMVT 242 A + F I+ R+ P+DD ++ L+ + T L +L + + Sbjct 183 AAEQGMVTGEVFEAYIDWRKDNPSDDIMTELLNVEFADETGTVRRLRREELLVYLNVVAG 242 Query 243 GGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVT 302 GN+T T ++G + +L PDQRR L+D+P IP AVEELLR P +AR TRD+ Sbjct 243 AGNETTTRLIGWAAKVLAEHPDQRRELVDNPALIPQAVEELLRFEPPAPHVARYVTRDIE 302 Query 303 IGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARM 362 I T+P G +L+L G+A RD RQ+ PD D+ R PR L FS G H+CLG+A AR+ Sbjct 303 IHGQTVPEGSVMLMLIGAAVRDHRQFPPDGDVFDIHREPRQHLAFSVGTHYCLGSALARL 362 Query 363 QCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVP 400 + R+AL E+L R P+++V + S S VR S+P Sbjct 363 EGRIALEEILKRFPEWDVDMANAALSPTSTVRGWDSMP 400 Lambda K H 0.320 0.135 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 804061019016 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40