BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv1266c Length=626 Score E Sequences producing significant alignments: (Bits) Value gi|15608406|ref|NP_215782.1| transmembrane serine/threonine-prot... 1276 0.0 gi|339297889|gb|AEJ49999.1| putative transmembrane serine/threon... 1275 0.0 gi|15840712|ref|NP_335749.1| serine/threonine protein kinase [My... 1274 0.0 gi|339294249|gb|AEJ46360.1| transmembrane serine/threonine-prote... 1273 0.0 gi|289573926|ref|ZP_06454153.1| transmembrane serine/threonine-p... 1273 0.0 gi|289446857|ref|ZP_06436601.1| transmembrane serine/threonine-p... 1273 0.0 gi|340626279|ref|YP_004744731.1| putative transmembrane serine/t... 1268 0.0 gi|289554945|ref|ZP_06444155.1| transmembrane serine/threonine-p... 1253 0.0 gi|289442702|ref|ZP_06432446.1| probable transmembrane serine/th... 1079 0.0 gi|121637194|ref|YP_977417.1| putative transmembrane serine/thre... 1077 0.0 gi|31792458|ref|NP_854951.1| transmembrane serine/threonine-prot... 1073 0.0 gi|342862145|ref|ZP_08718788.1| serine/threonine protein kinase ... 887 0.0 gi|118465657|ref|YP_880659.1| serine/threonine protein kinase [M... 872 0.0 gi|254774295|ref|ZP_05215811.1| serine/threonine-protein kinase ... 870 0.0 gi|254820140|ref|ZP_05225141.1| serine/threonine-protein kinase ... 812 0.0 gi|307083827|ref|ZP_07492940.1| putative protein kinase domain p... 720 0.0 gi|289749818|ref|ZP_06509196.1| LOW QUALITY PROTEIN: transmembra... 719 0.0 gi|289442704|ref|ZP_06432448.1| transmembrane serine/threonine-p... 718 0.0 gi|289569275|ref|ZP_06449502.1| predicted protein [Mycobacterium... 718 0.0 gi|340626281|ref|YP_004744733.1| putative serine/threonine-prote... 717 0.0 gi|289761418|ref|ZP_06520796.1| transmembrane serine/threonine-p... 706 0.0 gi|289573928|ref|ZP_06454155.1| transmembrane serine/threonine-p... 659 0.0 gi|183984127|ref|YP_001852418.1| transmembrane serine/threonine-... 650 0.0 gi|289757365|ref|ZP_06516743.1| transmembrane serine/threonine-p... 619 6e-175 gi|289753342|ref|ZP_06512720.1| predicted protein [Mycobacterium... 605 5e-171 gi|289446860|ref|ZP_06436604.1| transmembrane serine/threonine-p... 580 3e-163 gi|240173452|ref|ZP_04752110.1| transmembrane serine/threonine-p... 573 4e-161 gi|240173401|ref|ZP_04752059.1| transmembrane serine/threonine-p... 569 5e-160 gi|296170175|ref|ZP_06851770.1| non-specific serine/threonine pr... 550 2e-154 gi|183984140|ref|YP_001852431.1| transmembrane serine/threonine-... 548 2e-153 gi|183984142|ref|YP_001852433.1| transmembrane serine/threonine-... 539 6e-151 gi|41408602|ref|NP_961438.1| hypothetical protein MAP2504 [Mycob... 524 2e-146 gi|289749809|ref|ZP_06509187.1| transmembrane serine/threonine-p... 480 4e-133 gi|307083826|ref|ZP_07492939.1| hypothetical protein TMLG_02601 ... 451 2e-124 gi|240171192|ref|ZP_04749851.1| transmembrane serine/threonine-p... 442 1e-121 gi|240169468|ref|ZP_04748127.1| transmembrane serine/threonine-p... 434 3e-119 gi|183982591|ref|YP_001850882.1| transmembrane serine/threonine-... 431 2e-118 gi|118618539|ref|YP_906871.1| transmembrane serine/threonine-pro... 431 3e-118 gi|289757364|ref|ZP_06516742.1| transmembrane serine/threonine-p... 430 3e-118 gi|296164638|ref|ZP_06847204.1| possible non-specific serine/thr... 427 3e-117 gi|342860681|ref|ZP_08717331.1| putative transmembrane serine/th... 424 3e-116 gi|340626751|ref|YP_004745203.1| putative transmembrane serine/t... 422 9e-116 gi|120405645|ref|YP_955474.1| protein kinase [Mycobacterium vanb... 419 8e-115 gi|289446501|ref|ZP_06436245.1| transmembrane serine/threonine-p... 417 3e-114 gi|15608071|ref|NP_215446.1| transmembrane serine/threonine-prot... 415 1e-113 gi|254821942|ref|ZP_05226943.1| transmembrane serine/threonine-p... 415 1e-113 gi|289442346|ref|ZP_06432090.1| transmembrane serine/threonine-p... 415 1e-113 gi|339630994|ref|YP_004722636.1| Ser/Thr protein kinase D [Mycob... 415 2e-113 gi|306775061|ref|ZP_07413398.1| transmembrane serine/threonine-p... 413 4e-113 gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-... 410 5e-112 >gi|15608406|ref|NP_215782.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis H37Rv] gi|6093725|sp|Q11053.2|PKNH_MYCTU RecName: Full=Probable serine/threonine-protein kinase pknH gi|3261596|emb|CAB00914.1| PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE H PKNH (PROTEIN KINASE H) (STPK H) [Mycobacterium tuberculosis H37Rv] Length=626 Score = 1276 bits (3303), Expect = 0.0, Method: Compositional matrix adjust. Identities = 626/626 (100%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGYRITNQAGQIAAKIVDKVNKE Sbjct 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 >gi|339297889|gb|AEJ49999.1| putative transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CCDC5180] Length=641 Score = 1275 bits (3300), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 16 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 75 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 76 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 135 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 136 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 195 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 196 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 255 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 256 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 315 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 316 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 375 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 376 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 435 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 436 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 495 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 496 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 555 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 556 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 615 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 616 VNACGYQITNQAGQIAAKIVDKVNKE 641 >gi|15840712|ref|NP_335749.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|148661053|ref|YP_001282576.1| serine/threonine protein kinase [Mycobacterium tuberculosis H37Ra] gi|148822483|ref|YP_001287237.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis F11] 48 more sequence titles Length=626 Score = 1274 bits (3298), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 601 VNACGYQITNQAGQIAAKIVDKVNKE 626 >gi|339294249|gb|AEJ46360.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CCDC5079] Length=638 Score = 1273 bits (3294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 13 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 72 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 73 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 132 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 133 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 192 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 193 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 252 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 253 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 312 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 313 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 372 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 373 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 432 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 433 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 492 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 493 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 552 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 553 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 612 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 613 VNACGYQITNQAGQIAAKIVDKVNKE 638 >gi|289573926|ref|ZP_06454153.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis K85] gi|339631332|ref|YP_004722974.1| Ser/Thr protein kinase [Mycobacterium africanum GM041182] gi|289538357|gb|EFD42935.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis K85] gi|339330688|emb|CCC26357.1| putative membrane spanning serine/threonine protein kinase [Mycobacterium africanum GM041182] Length=626 Score = 1273 bits (3294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/626 (99%), Positives = 625/626 (99%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPV PPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVIPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 601 VNACGYQITNQAGQIAAKIVDKVNKE 626 >gi|289446857|ref|ZP_06436601.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] gi|289419815|gb|EFD17016.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] Length=626 Score = 1273 bits (3294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/626 (99%), Positives = 625/626 (99%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQD RVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDLRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 601 VNACGYQITNQAGQIAAKIVDKVNKE 626 >gi|340626279|ref|YP_004744731.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium canettii CIPT 140010059] gi|340004469|emb|CCC43612.1| putative transmembrane serine/threonine-protein kinase H PKNH (protein kinase H) (STPK H) [Mycobacterium canettii CIPT 140010059] Length=626 Score = 1268 bits (3282), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/626 (99%), Positives = 623/626 (99%), Gaps = 0/626 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 KPVPPPTMPATAMAPRQPPAPPVTPPG QPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGAQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 420 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 601 VNACGYQITNQAGQIAAKIVDKVNKE 626 >gi|289554945|ref|ZP_06444155.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis KZN 605] gi|289439577|gb|EFD22070.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis KZN 605] Length=615 Score = 1253 bits (3243), Expect = 0.0, Method: Compositional matrix adjust. Identities = 614/615 (99%), Positives = 615/615 (100%), Gaps = 0/615 (0%) Query 12 MFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIAGRL 71 MFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIAGRL Sbjct 1 MFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIAGRL 60 Query 72 QEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAH 131 QEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAH Sbjct 61 QEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAH 120 Query 132 ADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDE 191 ADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDE Sbjct 121 ADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDE 180 Query 192 VTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVA 251 VTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVA Sbjct 181 VTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVA 240 Query 252 RGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPAT 311 RGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPAT Sbjct 241 RGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPAT 300 Query 312 AMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTP 371 AMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTP Sbjct 301 AMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTP 360 Query 372 TPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPV 431 TPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPV Sbjct 361 TPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPV 420 Query 432 QPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQD 491 QPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQD Sbjct 421 QPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQD 480 Query 492 PVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVT 551 PVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVT Sbjct 481 PVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVT 540 Query 552 VTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYRITNQ 611 VTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGY+ITNQ Sbjct 541 VTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQ 600 Query 612 AGQIAAKIVDKVNKE 626 AGQIAAKIVDKVNKE Sbjct 601 AGQIAAKIVDKVNKE 615 >gi|289442702|ref|ZP_06432446.1| probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T46] gi|289415621|gb|EFD12861.1| probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T46] Length=534 Score = 1079 bits (2790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/534 (99%), Positives = 534/534 (100%), Gaps = 0/534 (0%) Query 93 MRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRDDF 152 MRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRDDF Sbjct 1 MRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRDDF 60 Query 153 AYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGA 212 AYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGA Sbjct 61 AYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGA 120 Query 213 PPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALAA 272 PPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALAA Sbjct 121 PPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALAA 180 Query 273 HEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAP 332 HEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAP Sbjct 181 HEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAP 240 Query 333 KPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPW 392 KPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPW Sbjct 241 KPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPW 300 Query 393 AQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEV 452 AQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEV Sbjct 301 AQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEV 360 Query 453 NAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGD 512 NAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGD Sbjct 361 NAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGD 420 Query 513 NYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPT 572 NYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPT Sbjct 421 NYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPT 480 Query 573 ITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 ITVIDTQEGAEGWECQRAMSVANNVVVDVNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 481 ITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQAGQIAAKIVDKVNKE 534 >gi|121637194|ref|YP_977417.1| putative transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989669|ref|YP_002644356.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium bovis BCG str. Tokyo 172] gi|121492841|emb|CAL71312.1| Probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772782|dbj|BAH25588.1| putative transmembrane serine/threonine-protein kinase H [Mycobacterium bovis BCG str. Tokyo 172] gi|341601212|emb|CCC63885.1| probable transmembrane serine/threonine-protein kinase H pknH [Mycobacterium bovis BCG str. Moreau RDJ] Length=596 Score = 1077 bits (2785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 580/626 (93%), Positives = 584/626 (94%), Gaps = 30/626 (4%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 298 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 299 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 330 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VAGAAAVVLVLVLGAI Sbjct 331 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAGAAAVVLVLVLGAI 390 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 391 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 450 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 451 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 510 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 511 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 570 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 571 VNACGYQITNQAGQIAAKIVDKVNKE 596 >gi|31792458|ref|NP_854951.1| transmembrane serine/threonine-protein kinase H [Mycobacterium bovis AF2122/97] gi|61214289|sp|Q7U095.1|PKNH_MYCBO RecName: Full=Probable serine/threonine-protein kinase pknH gi|31618047|emb|CAD94158.1| PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE H PKNH (PROTEIN KINASE H) (STPK H) [Mycobacterium bovis AF2122/97] Length=596 Score = 1073 bits (2775), Expect = 0.0, Method: Compositional matrix adjust. Identities = 580/626 (93%), Positives = 584/626 (94%), Gaps = 30/626 (4%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 298 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 299 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 330 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI Sbjct 331 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 390 Query 421 GIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 480 GIWIA RPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP Sbjct 391 GIWIANRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLP 450 Query 481 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 540 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD Sbjct 451 DCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSAD 510 Query 541 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 600 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD Sbjct 511 KWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVD 570 Query 601 VNACGYRITNQAGQIAAKIVDKVNKE 626 VNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 571 VNACGYQITNQAGQIAAKIVDKVNKE 596 >gi|342862145|ref|ZP_08718788.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] gi|342130449|gb|EGT83764.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] Length=624 Score = 887 bits (2292), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/633 (73%), Positives = 517/633 (82%), Gaps = 20/633 (3%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD Q SR GSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKL++ FS+DPVFRER Sbjct 1 MSDEQSSRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 +KREAR AGRLQEPHVVP+HDYGE+DGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 LKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRD+KPQNIL+TRDDFAYLVDFGIASATTD+KLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAGGVMHRDIKPQNILLTRDDFAYLVDFGIASATTDDKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS+ EVTYRADIYALACVL ECLTG PPYRADSAG LVS+H+M PIP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGTPPYRADSAGVLVSAHMMEPIPAPSEQRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 G+PKAFDAV+ARGMAKKPEDRYASAGDLALAA +ALS+PDQD AA ILRRSQE+ LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKQALSNPDQDRAATILRRSQEAALPTVE 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 P A QP P P P P A G A +W P Sbjct 301 NPGAQAHAAAAPPPAYQPTYTTPPPSPFDPPSAPISGPIAAQGAA----------AWTPT 350 Query 361 SGPMPASGPTPTPQYYQGG--GWGAPPSGGPS-PWAQTPRK--TNPWPLVAGAAAVVLVL 415 SGP+PA+G P P YYQGG WG PP S PW Q P K N WP++A A V++V+ Sbjct 351 SGPIPAAG-QPAPPYYQGGNANWGGPPQFTSSTPWGQPPPKPHRNIWPIIAAVAVVLVVI 409 Query 416 VLGAIGIWIAIRPKPVQPPQ--PVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSS 473 G +GIW+ +RPKP +PPQ P+ ERLS LLL+ +++N VMGSSSMQPGKPIT+ DSS Sbjct 410 ASG-VGIWLVVRPKP-EPPQAAPLGPERLSGLLLSPADINGVMGSSSMQPGKPITATDSS 467 Query 474 PVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARA 533 VTVS PDCQGALYT+QDPVYAG+GY+A++GL+SSE GDNY+HWVNQAVV FP+AD+A++ Sbjct 468 SVTVSAPDCQGALYTTQDPVYAGSGYSAVSGLVSSEAGDNYDHWVNQAVVLFPSADRAKS 527 Query 534 FVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSV 593 FVQTSA+KWK CAGKTVTVTNK+KTYRWTFA ++GSPP IT++DTQEGA+GWECQRA+SV Sbjct 528 FVQTSAEKWKGCAGKTVTVTNKSKTYRWTFAQLQGSPPKITMMDTQEGADGWECQRALSV 587 Query 594 ANNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 ANNVVVD+NACGY I++Q GQIA KIV K++ + Sbjct 588 ANNVVVDINACGYHISDQGGQIADKIVGKIDSD 620 >gi|118465657|ref|YP_880659.1| serine/threonine protein kinase [Mycobacterium avium 104] gi|118166944|gb|ABK67841.1| serine/threonine-protein kinase PknE [Mycobacterium avium 104] gi|336458610|gb|EGO37577.1| protein kinase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=604 Score = 872 bits (2254), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/632 (74%), Positives = 521/632 (83%), Gaps = 34/632 (5%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD + S+VGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKL+ FS DPVFRER Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVP+HDYGE+DGQMFLEMRLVEGTDLDSVLKRFGPL PPRAVAII Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNIL+TRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS+ EVTYRADIYALACVL ECLTG+ PYRADSAG LVS+H+M PIP PSA RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 G+PKAFDAV+ARGMAKKPEDRYASAGDLALAA EALS PDQD AA ILRRSQE+ LPA Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 + +T +AP PP V QPG A + G W P Sbjct 301 Q---RDAGASTVLAP---------PPAVN---------TRQPGSAASQAG----RGWTPE 335 Query 361 SGPMPASGPTPTPQYYQGG--GWGAPPS--GGPSPWAQTPRKTNPWPLVAGAAAVVLVLV 416 SGP+PA+G P P YYQGG W A P+ GP PW + P K WP+VA A VLV++ Sbjct 336 SGPIPAAG-QPGPPYYQGGNANWAAAPAQFAGPPPWGRPPPKRRVWPIVA-AVVAVLVVI 393 Query 417 LGAIGIWIAIRPKPVQPPQ--PVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSP 474 G +G+W+ IRPKP +PPQ P+ +RL ALLL++SEVNAVMGSS+M+PGKPIT+ DSS Sbjct 394 AGGVGVWLVIRPKP-EPPQAAPLTSDRLGALLLSASEVNAVMGSSTMEPGKPITATDSSS 452 Query 475 VTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAF 534 VTVS+PDCQGALYT+QDPVYAG+GY+A+NGL+SSEPGDNY+HWVNQAVV FP+ADKA++F Sbjct 453 VTVSVPDCQGALYTTQDPVYAGSGYSAVNGLVSSEPGDNYDHWVNQAVVLFPSADKAKSF 512 Query 535 VQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVA 594 +QTS KWK CAG+TVTVTNK+KTYRWTFA V+G+PP IT++DTQEGA+GWECQRA+SVA Sbjct 513 LQTSLQKWKGCAGQTVTVTNKSKTYRWTFAQVQGAPPKITLMDTQEGADGWECQRALSVA 572 Query 595 NNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 NNV+VD+NACGYRIT+Q QIA KIV K++ E Sbjct 573 NNVIVDINACGYRITDQGDQIADKIVAKIDNE 604 >gi|254774295|ref|ZP_05215811.1| serine/threonine-protein kinase PknE [Mycobacterium avium subsp. avium ATCC 25291] Length=604 Score = 870 bits (2248), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/632 (73%), Positives = 520/632 (83%), Gaps = 34/632 (5%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD + S+VGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKL+ FS DPVFRER Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVP+HDYGE+DGQMFLEMRLVEGTDLDSVLKRFGPL PPRAVAII Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNIL+TRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS+ EVTYRADIYALACVL ECLTG+ PYRADSAG LVS+H+M PIP PSA RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 G+PKAFDAV+ARGMAKKPEDRYASAGDLALAA EALS PDQD AA ILRRSQE+ LPA Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 + +T +AP PP V QPG A + G W P Sbjct 301 Q---RDAGASTVLAP---------PPAVN---------TRQPGSAASQAG----RGWTPE 335 Query 361 SGPMPASGPTPTPQYYQGG--GWGAPPS--GGPSPWAQTPRKTNPWPLVAGAAAVVLVLV 416 SGP+PA+G P P YYQGG W A P+ GP PW + P K WP+VA A VLV++ Sbjct 336 SGPIPAAG-QPGPPYYQGGNANWAAAPAQFAGPPPWGRPPPKRRVWPIVA-AVVAVLVVI 393 Query 417 LGAIGIWIAIRPKPVQPPQ--PVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSP 474 G +G+W+ IRPKP +PPQ P+ +RL ALLL++SEVNAVMGSS+M+PGKPIT+ DSS Sbjct 394 AGGVGVWLVIRPKP-EPPQAAPLTSDRLGALLLSASEVNAVMGSSTMEPGKPITATDSSS 452 Query 475 VTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAF 534 VTVS+PDCQGALYT+QDPVYAG+GY+A+NGL+SSE GDNY+HWVNQAVV FP+ADKA++F Sbjct 453 VTVSVPDCQGALYTTQDPVYAGSGYSAVNGLVSSEAGDNYDHWVNQAVVLFPSADKAKSF 512 Query 535 VQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVA 594 +QTS KWK CAG+TVTVTNK+KTYRWTFA V+G+PP IT++DTQEGA+GWECQRA+SVA Sbjct 513 LQTSLQKWKGCAGQTVTVTNKSKTYRWTFAQVQGAPPKITLMDTQEGADGWECQRALSVA 572 Query 595 NNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 NNV+VD+NACGYRIT+Q QIA KIV K++ E Sbjct 573 NNVIVDINACGYRITDQGDQIADKIVAKIDNE 604 >gi|254820140|ref|ZP_05225141.1| serine/threonine-protein kinase PknE [Mycobacterium intracellulare ATCC 13950] Length=588 Score = 812 bits (2098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/627 (70%), Positives = 488/627 (78%), Gaps = 40/627 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD Q SR GSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKL++ FS+DPVFRER Sbjct 1 MSDEQASRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVP+HDYGE+DGQ+FLEMRLVEGTDL SVLKRFGPLTPPRAVA+I Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQIFLEMRLVEGTDLGSVLKRFGPLTPPRAVAVI 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNIL+T DDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTADDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS+ EVTYRADIYALACVL ECLTGAPPYRADSAG LVS+H+M PIP PS RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGAPPYRADSAGMLVSAHMMDPIPAPSQRRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 IPKAFDAV+ARGMAK+PEDRYASAGDLALAA +ALS PDQD AA ILRRSQE+ LP Sbjct 241 DIPKAFDAVIARGMAKRPEDRYASAGDLALAAKQALSHPDQDRAATILRRSQEAALPTAV 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 P PR APP P+P Y P P P Q + A Sbjct 301 NP-----------DPRLSTAPP---------PRP-YQPAFNTPPPSPSAAPYYQGASANW 339 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 G P PQ+ WG PP PR L+ A AVV VL+ + Sbjct 340 GG--------PPPQFANATPWGQPP----------PRPRRNVWLIVAAVAVVFVLLGSGL 381 Query 421 GIWIAIR-PKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSL 479 GIW+ R PP P+ +RLSALLL S++N VMGSS+MQPGKPITS D S VTVS Sbjct 382 GIWLVTRPDPEPPPPAPLEADRLSALLLGPSDINTVMGSSTMQPGKPITSTDHSAVTVST 441 Query 480 PDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSA 539 PDCQGALYT+QDPVYAGTGYT+++GL+SSEPGDNY+HWVNQAVV FP+ADKA++F++ SA Sbjct 442 PDCQGALYTTQDPVYAGTGYTSVSGLVSSEPGDNYDHWVNQAVVLFPSADKAKSFLENSA 501 Query 540 DKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVV 599 +KWK CAGKTVTVTNK+KTYRWTFA V+GSPP IT++DTQEGA+GWECQRA++VANNV+V Sbjct 502 EKWKGCAGKTVTVTNKSKTYRWTFAQVQGSPPKITLMDTQEGADGWECQRALTVANNVIV 561 Query 600 DVNACGYRITNQAGQIAAKIVDKVNKE 626 D+NACGY I++Q QIA KI ++ E Sbjct 562 DINACGYHISDQGAQIADKIAARIADE 588 >gi|307083827|ref|ZP_07492940.1| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu012] gi|308366510|gb|EFP55361.1| putative protein kinase domain protein [Mycobacterium tuberculosis SUMu012] Length=353 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/353 (100%), Positives = 353/353 (100%), Gaps = 0/353 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTG 353 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTG Sbjct 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTG 353 >gi|289749818|ref|ZP_06509196.1| LOW QUALITY PROTEIN: transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] gi|289690405|gb|EFD57834.1| LOW QUALITY PROTEIN: transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] Length=490 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/428 (90%), Positives = 384/428 (90%), Gaps = 30/428 (7%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 17 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 76 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 77 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 136 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 137 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 196 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 197 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 256 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 257 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 314 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 315 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 346 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 347 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 406 Query 421 GIWIAIRP 428 GIWIA RP Sbjct 407 GIWIANRP 414 >gi|289442704|ref|ZP_06432448.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis T46] gi|289415623|gb|EFD12863.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis T46] Length=576 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/428 (90%), Positives = 384/428 (90%), Gaps = 30/428 (7%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 298 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 299 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 330 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 331 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 390 Query 421 GIWIAIRP 428 GIWIA RP Sbjct 391 GIWIANRP 398 >gi|289569275|ref|ZP_06449502.1| predicted protein [Mycobacterium tuberculosis T17] gi|289543029|gb|EFD46677.1| predicted protein [Mycobacterium tuberculosis T17] Length=588 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/428 (90%), Positives = 384/428 (90%), Gaps = 30/428 (7%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 13 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 72 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 73 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 132 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 133 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 192 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 193 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 252 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 253 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 310 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 311 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 342 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 343 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 402 Query 421 GIWIAIRP 428 GIWIA RP Sbjct 403 GIWIANRP 410 >gi|340626281|ref|YP_004744733.1| putative serine/threonine-protein kinase pknh [Mycobacterium canettii CIPT 140010059] gi|340004471|emb|CCC43614.1| putative serine/threonine-protein kinase pknh [Mycobacterium canettii CIPT 140010059] Length=576 Score = 717 bits (1851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/428 (89%), Positives = 384/428 (90%), Gaps = 30/428 (7%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 298 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 299 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 330 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGP+PWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 331 SGPMPASGPTPTPQYYQGGGWGAPPSGGPTPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 390 Query 421 GIWIAIRP 428 GIWIA RP Sbjct 391 GIWIANRP 398 >gi|289761418|ref|ZP_06520796.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis GM 1503] gi|289708924|gb|EFD72940.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis GM 1503] Length=352 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/351 (99%), Positives = 351/351 (100%), Gaps = 0/351 (0%) Query 276 LSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPS 335 LSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPS Sbjct 2 LSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPS 61 Query 336 YTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQT 395 YTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQT Sbjct 62 YTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQT 121 Query 396 PRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAV 455 PRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAV Sbjct 122 PRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAV 181 Query 456 MGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYE 515 MGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYE Sbjct 182 MGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYE 241 Query 516 HWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITV 575 HWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITV Sbjct 242 HWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITV 301 Query 576 IDTQEGAEGWECQRAMSVANNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 IDTQEGAEGWECQRAMSVANNVVVDVNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 302 IDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQAGQIAAKIVDKVNKE 352 >gi|289573928|ref|ZP_06454155.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis K85] gi|339631334|ref|YP_004722976.1| Ser/Thr protein kinase [Mycobacterium africanum GM041182] gi|289538359|gb|EFD42937.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium tuberculosis K85] gi|339330690|emb|CCC26359.1| putative membrane-spanning serine/threonine protein kinase [Mycobacterium africanum GM041182] Length=555 Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/428 (85%), Positives = 363/428 (85%), Gaps = 51/428 (11%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVT YRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVT---------------------YRADSAGTLVSSHLMGPIPQPSAIRP 219 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP Sbjct 220 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG-- 277 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 A+ + P P VTPP +Q A PTGQPSWAPN Sbjct 278 ---------TAAVTAQPPTMPTVTPPPIQAA-------------------PTGQPSWAPN 309 Query 361 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAI 420 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWP VA AAAVVLVLVLGAI Sbjct 310 SGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPFVAVAAAVVLVLVLGAI 369 Query 421 GIWIAIRP 428 GIWIA RP Sbjct 370 GIWIANRP 377 >gi|183984127|ref|YP_001852418.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium marinum M] gi|183177453|gb|ACC42563.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium marinum M] Length=596 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/433 (77%), Positives = 360/433 (84%), Gaps = 27/433 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 M +A DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMT EFSKDPVFRER Sbjct 1 MGEAPDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTTEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGE+DGQMFLEMRL+EGTDLDS+LKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTDLDSILKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKP NILITRDDFAYLVDFGIASAT DEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPPNILITRDDFAYLVDFGIASATGDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+N+EVTYRADIYALACVL ECLTG+PPYR+DSAGTLV++HLM P+PQ S +R Sbjct 181 YMAPERFANEEVTYRADIYALACVLFECLTGSPPYRSDSAGTLVTAHLMDPVPQVSTVRS 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAV+ARGMAKKPE+RYASAGDLA AAH+ALS+PDQDHAADILRRS+ESTLP Sbjct 241 GIPKAFDAVIARGMAKKPEERYASAGDLARAAHDALSNPDQDHAADILRRSRESTLPGTA 300 Query 301 KPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAP 359 P PPTMPA VTPP P Y PA GP Q PTGQP WAP Sbjct 301 AITPQPPTMPA------------VTPPPAMP-----YADPASSGPLPQS-APTGQPGWAP 342 Query 360 NSGPMPASG-PTPTPQYYQGGGWGAPPSG-------GPSPWAQTPRKTNPWPLVAGAAAV 411 SGP+PA+ P PQYYQ G W + P G GP+PW Q P K NPWP+VAG AA+ Sbjct 343 ASGPIPAAHQPAQVPQYYQSGSWASTPPGTPPQQPVGPTPWNQPPPKRNPWPIVAGVAAL 402 Query 412 VLVLVLGAIGIWI 424 V VL++G IG+W+ Sbjct 403 VFVLIVGGIGVWL 415 >gi|289757365|ref|ZP_06516743.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] gi|289712929|gb|EFD76941.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] Length=314 Score = 619 bits (1595), Expect = 6e-175, Method: Compositional matrix adjust. Identities = 299/299 (100%), Positives = 299/299 (100%), Gaps = 0/299 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 15 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 74 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 75 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 134 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 135 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 194 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 195 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 254 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP Sbjct 255 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 313 >gi|289753342|ref|ZP_06512720.1| predicted protein [Mycobacterium tuberculosis EAS054] gi|289693929|gb|EFD61358.1| predicted protein [Mycobacterium tuberculosis EAS054] Length=319 Score = 605 bits (1561), Expect = 5e-171, Method: Compositional matrix adjust. Identities = 293/297 (99%), Positives = 294/297 (99%), Gaps = 0/297 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 16 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 75 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 76 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 135 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 136 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 195 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 196 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 255 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLP 297 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQ + P Sbjct 256 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQAAKNP 312 >gi|289446860|ref|ZP_06436604.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] gi|289419818|gb|EFD17019.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis CPHL_A] Length=300 Score = 580 bits (1495), Expect = 3e-163, Method: Compositional matrix adjust. Identities = 287/301 (96%), Positives = 288/301 (96%), Gaps = 1/301 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER Sbjct 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII Sbjct 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRA LTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP Sbjct 181 YMAPERFSNDEVTYRA-TSTRWLRAARMLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 239 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP Sbjct 240 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPR 299 Query 301 K 301 + Sbjct 300 R 300 >gi|240173452|ref|ZP_04752110.1| transmembrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=353 Score = 573 bits (1476), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 283/313 (91%), Positives = 295/313 (95%), Gaps = 0/313 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQ SRVGS FGPY LKRLLGRGGMGEVYEAEHTVKEWTVAVKLM+ FSKDPVFRER Sbjct 1 MSDAQGSRVGSTFGPYRLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMSETFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARI GRLQEPHVVPIHDYGE+DGQM+LEMRL+EGTDLD +LKRFGPLTPPRAVAII Sbjct 61 MKREARITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDHILKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNIL+TRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTG+PPYRADSA LV++HLM PIPQPS +R Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGSPPYRADSASMLVTAHLMDPIPQPSTLRS 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAV+ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQE+TLP PP Sbjct 241 GIPKAFDAVIARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQEATLPGPP 300 Query 301 KPVPPPTMPATAM 313 V PPTMPAT M Sbjct 301 TAVAPPTMPATGM 313 >gi|240173401|ref|ZP_04752059.1| transmembrane serine/threonine-protein kinase H PknH [Mycobacterium kansasii ATCC 12478] Length=592 Score = 569 bits (1467), Expect = 5e-160, Method: Compositional matrix adjust. Identities = 328/437 (76%), Positives = 364/437 (84%), Gaps = 27/437 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 M +A DSRVGSMFGPYHLKRLLGRGGMGEVYEAE+TVKEW AVKLMTAEFSKDPVFRER Sbjct 1 MGEAPDSRVGSMFGPYHLKRLLGRGGMGEVYEAENTVKEWPCAVKLMTAEFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVPIHDYGE+DGQM+LEMRL+EGTDLD++LKRFGPLTPPRAVAII Sbjct 61 MKREARTAGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDTLLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 +Q+ASALDAAHA GVMHRDVKP N+L+TRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 SQVASALDAAHAAGVMHRDVKPPNVLVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVL+ECLTG+PPYRADSA TLV++HLM P+PQ SA+R Sbjct 181 YMAPERFSNDEVTYRADIYALACVLYECLTGSPPYRADSASTLVTAHLMDPVPQASAVRS 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPK DAV+ARGMAK+PEDRYASAGD A AAH+ALSDPDQDHAADILRRSQE+TL Sbjct 241 GIPKGLDAVIARGMAKRPEDRYASAGDFARAAHDALSDPDQDHAADILRRSQEATL---- 296 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPN 360 P TA AP+ P TPP P+P+ + P P PTGQP+WAP Sbjct 297 --------PGTAFAPQPPTLAAATPPPAPQYPEPAGSGPLPPA------SPTGQPAWAPA 342 Query 361 SGPMPASG-PTPTPQYYQGGGWGAPPS-------GGPSPWAQ-TPRKTNPWPLVAGAAAV 411 SGP+PA+G P P PQYYQGGGWG P GGP+PW Q R+ NPWP+VAGAAA+ Sbjct 343 SGPIPAAGQPAPVPQYYQGGGWGGTPPGTPPQQLGGPAPWNQPASRQRNPWPIVAGAAAL 402 Query 412 VLVLVLGAIGIWIAIRP 428 V+VLV+ AIG+W+A RP Sbjct 403 VVVLVVAAIGVWLATRP 419 >gi|296170175|ref|ZP_06851770.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895167|gb|EFG74883.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=625 Score = 550 bits (1418), Expect = 2e-154, Method: Compositional matrix adjust. Identities = 291/368 (80%), Positives = 309/368 (84%), Gaps = 12/368 (3%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD Q SRVGS FGPY LKRLLGRGGMGEVYEAEHTVKEWTVAVKL++ FS+DPVFRER Sbjct 1 MSDEQASRVGSNFGPYRLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVPIHDYGE+DGQMFLEMRL+EGTDLDSVLKRFGPL PPRAVAII Sbjct 61 MKREARTAGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTDLDSVLKRFGPLAPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSN EVTYRADIYALACVL+ECLTG PPYRADSA LV++H+M PIPQP+A+RP Sbjct 181 YMAPERFSNAEVTYRADIYALACVLYECLTGTPPYRADSASVLVTAHMMDPIPQPTALRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIPKAFDAV+ARGMAKKP+DRYASAGDLALAAH+ALSDPDQDHAA ILRRSQE+TLP Sbjct 241 GIPKAFDAVIARGMAKKPQDRYASAGDLALAAHDALSDPDQDHAATILRRSQEATLPGTA 300 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTP-PAQPGPAGQRPGPTGQPSWAP 359 P PT+ TAMAP P P P TP PAQ G P W P Sbjct 301 TLGPQPTVADTAMAPPATPPSPAPTANTPPPSAAGLTPVPAQ-----------GAPPWRP 349 Query 360 NSGPMPAS 367 SGP P++ Sbjct 350 ESGPFPSA 357 >gi|183984140|ref|YP_001852431.1| transmembrane serine/threonine-protein kinase H, PknH_1 [Mycobacterium marinum M] gi|183177466|gb|ACC42576.1| transmembrane serine/threonine-protein kinase H, PknH_1 [Mycobacterium marinum M] Length=617 Score = 548 bits (1411), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 294/447 (66%), Positives = 333/447 (75%), Gaps = 17/447 (3%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MS+A +R GSMFGPY L R LGRGGMG+VYEAEHTVK W VAVKLM+ FS DPVFRER Sbjct 1 MSEAPSARAGSMFGPYRLIRPLGRGGMGQVYEAEHTVKGWAVAVKLMSETFSSDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARI GRLQEPHVVPIHDYGE+DGQMFLEMRL+EGT+LDS+LKRFGPLTPPRAVAII Sbjct 61 MKREARITGRLQEPHVVPIHDYGEIDGQMFLEMRLIEGTNLDSLLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHAD VMHRDVKP NILITRDDFAYLVDFGIA+A TDEKLTQ+GTAVGTWK Sbjct 121 TQIASALDAAHADEVMHRDVKPPNILITRDDFAYLVDFGIANAATDEKLTQMGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ND VT+ ADIYALACVLHE LTG+ PY++++AG L+S+H+M PIP+PSA+ P Sbjct 181 YMAPERFTNDRVTHHADIYALACVLHESLTGSAPYQSNNAGLLISAHMMEPIPKPSAVHP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 IPKAFDAV+ARGMAKKP DRYASAGDLA AAH+ALS PDQ+ A ILRRSQ+STLP Sbjct 241 EIPKAFDAVIARGMAKKPADRYASAGDLARAAHQALSTPDQNQAETILRRSQQSTLPG-- 298 Query 301 KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQP-GPAGQRPGPTGQPSWAP 359 + V PT+ PR PA P G PA P + P GP GP GQP+W+P Sbjct 299 QVVEQPTL-EHRREPRCGPANPQHSSGPMPAYSSEPIPRSGPSGPTHPPSGPIGQPAWSP 357 Query 360 NSGP-MPASGPTPTPQYYQGGGWGAPPS-------GGPSPW-----AQTPRKTNPWPLVA 406 + P PA P P + G GA P GG W + PR NPW +V+ Sbjct 358 GAHPAAPAHSPVAPPPWDGGMSPGAAPRALAPQQLGGTPAWNPGVPQRPPRARNPWAIVS 417 Query 407 GAAAVVLVLVLGAIGIWIAIRPKPVQP 433 G A +LV++L AI IW A QP Sbjct 418 GVAVAILVMILVAIVIWAATHDDNPQP 444 >gi|183984142|ref|YP_001852433.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] gi|183177468|gb|ACC42578.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum M] Length=667 Score = 539 bits (1389), Expect = 6e-151, Method: Compositional matrix adjust. Identities = 263/296 (89%), Positives = 281/296 (95%), Gaps = 0/296 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDAQ SRVGS FGPY L RLLGRGGMGEVYEAEHTVKEWTVAVKLM+ FSKDPVFRER Sbjct 1 MSDAQGSRVGSTFGPYRLTRLLGRGGMGEVYEAEHTVKEWTVAVKLMSETFSKDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREARI GRLQEPHVVPIHDYGE+DGQM+LEMRL+EGTDLD++LKRFGPLTPPRAVAII Sbjct 61 MKREARITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTDLDNLLKRFGPLTPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQ+ASALDAAHA GVMHRDVKPQNIL+TR+DFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQVASALDAAHAAGVMHRDVKPQNILVTREDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFSNDEVTYRADIYALACVLHECLTG+PPYRADSA LV++H+M PIPQPS +R Sbjct 181 YMAPERFSNDEVTYRADIYALACVLHECLTGSPPYRADSASMLVTAHMMDPIPQPSTVRA 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTL 296 GIPKAFD V+ARGMAK+P DRYASAGDLALAAHEALS+PDQDHAADILRRSQE+TL Sbjct 241 GIPKAFDTVIARGMAKQPGDRYASAGDLALAAHEALSNPDQDHAADILRRSQEATL 296 >gi|41408602|ref|NP_961438.1| hypothetical protein MAP2504 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396960|gb|AAS04821.1| hypothetical protein MAP_2504 [Mycobacterium avium subsp. paratuberculosis K-10] Length=401 Score = 524 bits (1349), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 268/321 (84%), Positives = 282/321 (88%), Gaps = 0/321 (0%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSD + S+VGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKL+ FS DPVFRER Sbjct 1 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNESFSSDPVFRER 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 MKREAR AGRLQEPHVVP+HDYGE+DGQMFLEMRLVEGTDLDSVLKRFGPL PPRAVAII Sbjct 61 MKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTDLDSVLKRFGPLPPPRAVAII 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 TQIASALDAAHA GVMHRDVKPQNIL+TRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK Sbjct 121 TQIASALDAAHAAGVMHRDVKPQNILVTRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS+ EVTYRADIYALACVL ECLTG+ PYRADSAG LVS+H+M PIP PSA RP Sbjct 181 YMAPERFSDAEVTYRADIYALACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRP 240 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 G+PKAFDAV+ARGMAKKPEDRYASAGDLALAA EALS PDQD AA ILRRSQE+ LP Sbjct 241 GVPKAFDAVIARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPPRG 300 Query 301 KPVPPPTMPATAMAPRQPPAP 321 P P P P +P Sbjct 301 SATPGPARCWRHRLPSTPGSP 321 >gi|289749809|ref|ZP_06509187.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] gi|289690396|gb|EFD57825.1| transmembrane serine/threonine-protein kinase H pknH [Mycobacterium tuberculosis T92] Length=303 Score = 480 bits (1235), Expect = 4e-133, Method: Compositional matrix adjust. Identities = 284/284 (100%), Positives = 284/284 (100%), Gaps = 0/284 (0%) Query 152 FAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTG 211 FAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTG Sbjct 1 FAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTG 60 Query 212 APPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALA 271 APPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALA Sbjct 61 APPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALA 120 Query 272 AHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPA 331 AHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPA Sbjct 121 AHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPA 180 Query 332 PKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSP 391 PKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSP Sbjct 181 PKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSP 240 Query 392 WAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQ 435 WAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQ Sbjct 241 WAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQ 284 >gi|307083826|ref|ZP_07492939.1| hypothetical protein TMLG_02601 [Mycobacterium tuberculosis SUMu012] gi|308366543|gb|EFP55394.1| hypothetical protein TMLG_02601 [Mycobacterium tuberculosis SUMu012] Length=222 Score = 451 bits (1159), Expect = 2e-124, Method: Compositional matrix adjust. Identities = 220/222 (99%), Positives = 222/222 (100%), Gaps = 0/222 (0%) Query 405 VAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPG 464 +AGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPG Sbjct 1 MAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPG 60 Query 465 KPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVA 524 KPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVA Sbjct 61 KPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVA 120 Query 525 FPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEG 584 FPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEG Sbjct 121 FPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEG 180 Query 585 WECQRAMSVANNVVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 WECQRAMSVANNVVVDVNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 181 WECQRAMSVANNVVVDVNACGYQITNQAGQIAAKIVDKVNKE 222 >gi|240171192|ref|ZP_04749851.1| transmembrane serine/threonine-protein kinase H PknH_2 [Mycobacterium kansasii ATCC 12478] Length=585 Score = 442 bits (1136), Expect = 1e-121, Method: Compositional matrix adjust. Identities = 214/286 (75%), Positives = 252/286 (89%), Gaps = 0/286 (0%) Query 9 VGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIA 68 +G+ FGPY+LKRLLG GGMGEVYEA TV++ VA+KLM+ S DPVFR RM+REAR A Sbjct 1 MGTRFGPYYLKRLLGTGGMGEVYEAVDTVRQRVVALKLMSESLSHDPVFRMRMQREARNA 60 Query 69 GRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALD 128 GRLQEPHVVPIHDYGE+DGQ++L+MRL+EGT L +L+RFGP+TPP AVA++ Q+A+ALD Sbjct 61 GRLQEPHVVPIHDYGEIDGQLYLDMRLIEGTHLALLLERFGPVTPPWAVALVHQVAAALD 120 Query 129 AAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFS 188 AAHA GVMHRDVKP+NIL+TRDDF YLVDFGIASA TDEKLTQLG+AVGTW+YMAPERFS Sbjct 121 AAHAAGVMHRDVKPENILVTRDDFVYLVDFGIASAATDEKLTQLGSAVGTWRYMAPERFS 180 Query 189 NDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDA 248 + EVT+RADIY+L CVLHECLTG PPYRADSAG L+++HLM PIP+PS +RPGIP AFDA Sbjct 181 DAEVTHRADIYSLTCVLHECLTGTPPYRADSAGMLITAHLMAPIPRPSQLRPGIPAAFDA 240 Query 249 VVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQES 294 V+ARGMAK+PEDRYASAGDLALAAH+ALS P Q IL+RS+E+ Sbjct 241 VIARGMAKRPEDRYASAGDLALAAHQALSGPHQAQEFRILKRSEEA 286 >gi|240169468|ref|ZP_04748127.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium kansasii ATCC 12478] Length=607 Score = 434 bits (1115), Expect = 3e-119, Method: Compositional matrix adjust. Identities = 237/393 (61%), Positives = 279/393 (71%), Gaps = 33/393 (8%) Query 6 DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREA 65 DSR GS FG Y L+RL+GRG MG+VYEAE TV+E VA+KLM+ S DPVFR RM+REA Sbjct 7 DSREGSQFGQYRLRRLVGRGAMGDVYEAEDTVRERVVALKLMSPTLSSDPVFRTRMQREA 66 Query 66 RIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIAS 125 R AGRL EPHVVPIHDYGE+DGQ++++MRL++G DL ++LKR+GPLTPPRAVA++ QI S Sbjct 67 RTAGRLHEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAILKRYGPLTPPRAVAVVRQIGS 126 Query 126 ALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPE 185 ALDAAHA GV HRDVKP+NIL++ DDFAYLVDFGIASAT+DEKLTQLG+ VGT YMAPE Sbjct 127 ALDAAHAAGVTHRDVKPENILVSGDDFAYLVDFGIASATSDEKLTQLGSTVGTLYYMAPE 186 Query 186 RFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKA 245 RF+N EVTYRADIYALACVL+ECLTG+PPYR D +++ +HL IP+PSA RPGIP A Sbjct 187 RFANTEVTYRADIYALACVLYECLTGSPPYRGDQL-SVMGAHLSQAIPRPSAARPGIPAA 245 Query 246 FDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPP 305 FD V+ARGMAK P DRYA+ GDL+ AA+ AL+ PDQD A DIL+RSQ + LPA Sbjct 246 FDQVIARGMAKDPADRYATCGDLSAAAYAALATPDQDRATDILQRSQVAQLPAAAV---- 301 Query 306 PTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMP 365 PA AP P P PS TP AQP G P P+P Sbjct 302 -GQPAAGFAP--------------PMPTPS-TPAAQPA---------GWSPPTPPGSPVP 336 Query 366 ASGPTPTPQYYQGGGWGA--PPSGGPSPWAQTP 396 P PTP + GWG P + G PW Q P Sbjct 337 TGAPQPTP-WTGATGWGTGYPGTAGAPPWGQPP 368 >gi|183982591|ref|YP_001850882.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium marinum M] gi|183175917|gb|ACC41027.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium marinum M] Length=608 Score = 431 bits (1109), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 230/362 (64%), Positives = 272/362 (76%), Gaps = 15/362 (4%) Query 1 MSDAQ-DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRE 59 MSDA DSR GS FGPY L+R++GRG MG+VYEAE TV+E VA+KLM+ S DPVFR Sbjct 1 MSDATADSREGSQFGPYRLRRIVGRGAMGDVYEAEDTVRERVVALKLMSQTLSNDPVFRT 60 Query 60 RMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAI 119 RM+REAR AGRLQEPHVVPIHDYGE+DGQ++++MRL++G DL ++LKR+GPL PPRAVAI Sbjct 61 RMQREARTAGRLQEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAMLKRYGPLPPPRAVAI 120 Query 120 ITQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTW 179 QI SALDAAHA GV HRDVKP+NIL++ DDFAYLVDFGIASAT+DEKLTQLG+ VGT Sbjct 121 TRQIGSALDAAHAAGVTHRDVKPENILVSHDDFAYLVDFGIASATSDEKLTQLGSTVGTL 180 Query 180 KYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIR 239 YMAPERFS+ +VTYRADIYALACVL+ECLTG+PPYR D +++ +HL PIP+PSA R Sbjct 181 YYMAPERFSSGDVTYRADIYALACVLYECLTGSPPYRGDQL-SVMGAHLSQPIPRPSAAR 239 Query 240 PGIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 PGIP FD V+ARGMAK P DRYA+ GDL+ AA+ AL+ PDQD A DIL+RSQ + LPA Sbjct 240 PGIPAGFDNVIARGMAKDPADRYATCGDLSAAAYSALATPDQDRATDILQRSQVAQLPAG 299 Query 300 PKPVPPPTMPATAMAPRQPPAPPVTPPGVQPA---PKPSYTPPAQPGPAGQRPGP-TGQP 355 PP P +P V PG P+ P PS P A P+ P P G P Sbjct 300 FASTPPGGF--------APSSPAVPVPGSAPSTGWPAPS-VPGAPVAPSAPVPTPWAGVP 350 Query 356 SW 357 W Sbjct 351 GW 352 >gi|118618539|ref|YP_906871.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium ulcerans Agy99] gi|118570649|gb|ABL05400.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium ulcerans Agy99] Length=587 Score = 431 bits (1107), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 229/362 (64%), Positives = 273/362 (76%), Gaps = 15/362 (4%) Query 1 MSDAQ-DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRE 59 MSDA DSR GS FGPY L+R++GRG MG+VYEAE TV+E VA+KLM+ S DPVFR Sbjct 1 MSDATADSREGSQFGPYRLRRIVGRGAMGDVYEAEDTVRERVVALKLMSQTLSNDPVFRT 60 Query 60 RMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAI 119 RM+REAR AGRLQEPHVVPIHDYGE+DGQ++++MRL++G DL ++LKR+GPL PPRAVAI Sbjct 61 RMQREARTAGRLQEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAMLKRYGPLPPPRAVAI 120 Query 120 ITQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTW 179 QI SALDAAHA GV HRDVKP+NIL++ DDFAYLVDFGIASAT+DEKLTQLG+ VGT Sbjct 121 TRQIGSALDAAHAAGVTHRDVKPENILVSHDDFAYLVDFGIASATSDEKLTQLGSTVGTL 180 Query 180 KYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIR 239 YMAPERFS+ +VTYRADIYALACVL+ECLTG+PPYR D +++ +HL PIP+PSA R Sbjct 181 YYMAPERFSSGDVTYRADIYALACVLYECLTGSPPYRGDQL-SVIGAHLSQPIPRPSAAR 239 Query 240 PGIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 PGIP FD V+ARGMAK P DRYA+ GDL+ AA+ AL+ PDQD A DIL+RSQ + LPA Sbjct 240 PGIPAGFDNVIARGMAKDPADRYATCGDLSAAAYSALATPDQDRATDILQRSQVAQLPA- 298 Query 300 PKPVPPPTMPATAMAPRQPPAPPVTPPGVQPA---PKPSYTPPAQPGPAGQRPGP-TGQP 355 +T+ P +P V PG P+ P PS P A P+ P P G P Sbjct 299 -------GFASTSPGGFAPSSPAVPVPGSAPSTGWPAPS-VPGAPVAPSAPVPTPWAGVP 350 Query 356 SW 357 W Sbjct 351 GW 352 >gi|289757364|ref|ZP_06516742.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] gi|289712928|gb|EFD76940.1| transmembrane serine/threonine-protein kinase H [Mycobacterium tuberculosis T85] Length=210 Score = 430 bits (1106), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 208/210 (99%), Positives = 210/210 (100%), Gaps = 0/210 (0%) Query 417 LGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVT 476 +GAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVT Sbjct 1 MGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVT 60 Query 477 VSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQ 536 VSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQ Sbjct 61 VSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQ 120 Query 537 TSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANN 596 TSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANN Sbjct 121 TSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANN 180 Query 597 VVVDVNACGYRITNQAGQIAAKIVDKVNKE 626 VVVDVNACGY+ITNQAGQIAAKIVDKVNKE Sbjct 181 VVVDVNACGYQITNQAGQIAAKIVDKVNKE 210 >gi|296164638|ref|ZP_06847204.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899946|gb|EFG79386.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=318 Score = 427 bits (1098), Expect = 3e-117, Method: Compositional matrix adjust. Identities = 205/293 (70%), Positives = 246/293 (84%), Gaps = 1/293 (0%) Query 6 DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREA 65 DSR GS FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR RM+REA Sbjct 7 DSREGSQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSQTLSNDPVFRSRMQREA 66 Query 66 RIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIAS 125 R AGRLQEPHVVPIHD+GE+DGQ++++MRL++G DL +L R+G L+PPRAVAI+ QI S Sbjct 67 RTAGRLQEPHVVPIHDFGEIDGQLYVDMRLIDGKDLAGMLSRYGALSPPRAVAIVRQIGS 126 Query 126 ALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPE 185 ALDAAHA GV+HRDVKP+NIL++ DDFAYLVDFGIASA+ DEKLTQ+GT VGT KYMAPE Sbjct 127 ALDAAHAAGVLHRDVKPENILVSSDDFAYLVDFGIASASADEKLTQIGTTVGTVKYMAPE 186 Query 186 RFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKA 245 RFS+ EVT+RADIYAL CVL+ECLTG+PPY D G ++ +HL IPQPSA RPGIP A Sbjct 187 RFSDSEVTHRADIYALGCVLYECLTGSPPYTGDQIG-VIGAHLHQAIPQPSAARPGIPAA 245 Query 246 FDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPA 298 FDAV+ARGMAK P DRYA+ GDL+ AA+ AL++PD+D A DIL+RSQ + PA Sbjct 246 FDAVIARGMAKNPADRYATCGDLSAAAYAALAEPDRDRATDILQRSQVARPPA 298 >gi|342860681|ref|ZP_08717331.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium colombiense CECT 3035] gi|342131705|gb|EGT84962.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium colombiense CECT 3035] Length=601 Score = 424 bits (1090), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 234/426 (55%), Positives = 286/426 (68%), Gaps = 43/426 (10%) Query 1 MSDAQ-DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRE 59 M DA DSR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR Sbjct 3 MGDATADSREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSRTLSNDPVFRS 62 Query 60 RMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAI 119 RM+REAR AGRL EPHVVPIHD+GE+DGQ++++MRL++G DL S+LKR+GP++PPRA+AI Sbjct 63 RMQREARTAGRLHEPHVVPIHDFGEIDGQLYVDMRLIDGKDLASMLKRYGPISPPRAIAI 122 Query 120 ITQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTW 179 + QI SALDAAH G++HRDVKP+NIL++ DDFAYLVDFGIASAT+DEKLTQ GT VGT Sbjct 123 VRQIGSALDAAHTAGILHRDVKPENILVSADDFAYLVDFGIASATSDEKLTQFGTTVGTA 182 Query 180 KYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIR 239 KYMAPERF + E+T +ADIYALACVL+ECLTG+PPY D +++ +H+ PIP+PSA R Sbjct 183 KYMAPERFGDSEITAKADIYALACVLYECLTGSPPYTGDQL-SVMGAHMHQPIPRPSAAR 241 Query 240 PGIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 P IP AFD V+ARGMAK P DR+ + GDL+ AA+ AL+ PDQD A DIL RSQ +T PA Sbjct 242 PSIPAAFDGVIARGMAKDPADRFLTCGDLSAAAYGALAAPDQDRATDILERSQMATPPAA 301 Query 300 PKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAP 359 P P G PAP P AQP AG P QP+ Sbjct 302 FAGQPAGGFAPGPPVAAP----APPPLGGWPAP-----PAAQPLTAG---APGLQPA--- 346 Query 360 NSGPMPASGPTPTPQYYQGGGWGAPP----SGGPSPWAQTPRKT-NPWPLVAGAAAVVLV 414 WG PP +G PW Q PR + PW L G AA + V Sbjct 347 --------------------AWGGPPVWTNAGATPPWGQPPRSSRKPW-LWVGVAATLTV 385 Query 415 LVLGAI 420 ++G I Sbjct 386 ALIGVI 391 >gi|340626751|ref|YP_004745203.1| putative transmembrane serine/threonine-protein kinase E [Mycobacterium canettii CIPT 140010059] gi|340004941|emb|CCC44089.1| putative transmembrane serine/threonine-protein kinase E PKNE (protein kinase E) (STPK E) [Mycobacterium canettii CIPT 140010059] Length=566 Score = 422 bits (1085), Expect = 9e-116, Method: Compositional matrix adjust. Identities = 216/337 (65%), Positives = 256/337 (76%), Gaps = 8/337 (2%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 M +SR G+ FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR R Sbjct 1 MDGTAESREGTQFGPYRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPVFRTR 60 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REAR AGRLQEPHVVPIHD+GE+DGQ++++MRL+ G DL ++L+R GPL PPRAVAI+ Sbjct 61 MQREARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QI SALDAAHA GV HRDVKP+NIL++ DDFAYLVDFGIASATTDEKLTQLG VGT Sbjct 121 RQIGSALDAAHAAGVTHRDVKPENILVSADDFAYLVDFGIASATTDEKLTQLGNTVGTLY 180 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERFS TYRADIYAL CVL+ECLTG+PPY+ D +++ +H+ IP+PS +RP Sbjct 181 YMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQL-SVMGAHINQAIPRPSTVRP 239 Query 241 GIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP 300 GIP AFDAV+ARGMAK PEDRY + GDL+ AAH AL+ DQD A DILRRSQ + LP P Sbjct 240 GIPVAFDAVIARGMAKNPEDRYVTCGDLSAAAHAALATADQDRATDILRRSQVAKLPVPS 299 Query 301 -KPVPP------PTMPATAMAPRQPPAPPVTPPGVQP 330 PV P PT A P PP+ P+ QP Sbjct 300 THPVSPGTRWPQPTPWAGGAPPWGPPSSPLPRSARQP 336 >gi|120405645|ref|YP_955474.1| protein kinase [Mycobacterium vanbaalenii PYR-1] gi|119958463|gb|ABM15468.1| protein kinase [Mycobacterium vanbaalenii PYR-1] Length=574 Score = 419 bits (1077), Expect = 8e-115, Method: Compositional matrix adjust. Identities = 200/299 (67%), Positives = 243/299 (82%), Gaps = 1/299 (0%) Query 1 MSDAQ-DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRE 59 M+D Q SRVGS GPY L+RLLG+GGMGEVYEAE TVK+ VA+KL+ S DPVFR+ Sbjct 1 MTDPQRGSRVGSQVGPYRLRRLLGKGGMGEVYEAEDTVKDRVVALKLLPEAVSHDPVFRK 60 Query 60 RMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAI 119 R++REA AGRLQEPHVVPIHDYGEVDG +F++MRL++GTDL +LK GP+TP RA AI Sbjct 61 RLQREAHAAGRLQEPHVVPIHDYGEVDGLLFVDMRLIDGTDLRKLLKEQGPMTPARATAI 120 Query 120 ITQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTW 179 + Q+ASALDAAH +G+MHRDVKP+NILI RDDFAYLVDFGIA+A TDE LT+LGTAVGT+ Sbjct 121 VAQVASALDAAHQNGIMHRDVKPENILINRDDFAYLVDFGIANAVTDEALTELGTAVGTY 180 Query 180 KYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIR 239 YMAPERF+N EVT+RAD+YAL CVLHECLTGA P++ DS ++++HL P P+PS R Sbjct 181 AYMAPERFTNGEVTHRADVYALTCVLHECLTGAQPFQGDSVSVVITAHLNDPAPRPSQSR 240 Query 240 PGIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPA 298 PGIP D V++RGMAK+PEDRYASAG++A AA AL+ QD A IL+RSQ +T+ A Sbjct 241 PGIPAGLDDVISRGMAKRPEDRYASAGEMARAATAALTGAQQDQADSILQRSQAATMMA 299 >gi|289446501|ref|ZP_06436245.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis CPHL_A] gi|289419459|gb|EFD16660.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis CPHL_A] Length=664 Score = 417 bits (1071), Expect = 3e-114, Method: Compositional matrix adjust. Identities = 240/432 (56%), Positives = 295/432 (69%), Gaps = 30/432 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDA +VGS FGPY L RLLGRGGMGEVYEAE T K VA+KL++ ++S + VFR R Sbjct 1 MSDAV-PQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRAR 59 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REA AGRL EPH+VPIHDYGE++GQ F+EMR+++GT L ++LK++GPLTP RAVAI+ Sbjct 60 MQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIV 119 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QIA+ALDAAHA+GV HRDVKP+NIL+T DFAYLVDFGIA A +D LTQ GTAVGT+ Sbjct 120 RQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYN 179 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ DEVTYRADIYALACVL ECLTGAPPYRADS L+++HLM P PQPS +RP Sbjct 180 YMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRP 239 Query 241 G-IPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 G +P A D V+A+GMAK P +R+ SAGDLA+AAH+AL+ +Q A ILRR +TL A Sbjct 240 GRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLAT 299 Query 300 PKPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWA 358 P + A A PP TP + +P S T A P A R G +W Sbjct 300 PADTGLSQSESGIAGAGTGPP----TPGAARWSPGDSAT-VAGPLAADSRGG-----NWP 349 Query 359 PNSGPMPASGPTPTPQYYQGG-GWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVL 417 +G PA P Q G+ PP+G K W +V GAAA+VLV ++ Sbjct 350 SQTGHSPA-----VPNALQASLGYAVPPAG---------NKRKVWAVV-GAAAIVLVAIV 394 Query 418 GAIGIWIAIRPK 429 A G ++ +RP Sbjct 395 AAAG-YLVLRPS 405 >gi|15608071|ref|NP_215446.1| transmembrane serine/threonine-protein kinase D PKND (protein kinase D) (STPK D) [Mycobacterium tuberculosis H37Rv] gi|15840354|ref|NP_335391.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|148660710|ref|YP_001282233.1| serine/threonine protein kinase [Mycobacterium tuberculosis H37Ra] 62 more sequence titles Length=664 Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 240/432 (56%), Positives = 294/432 (69%), Gaps = 30/432 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDA +VGS FGPY L RLLGRGGMGEVYEAE T K VA+KL++ ++S + VFR R Sbjct 1 MSDAV-PQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRAR 59 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REA AGRL EPH+VPIHDYGE++GQ F+EMR+++GT L ++LK++GPLTP RAVAI+ Sbjct 60 MQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIV 119 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QIA+ALDAAHA+GV HRDVKP+NIL+T DFAYLVDFGIA A +D LTQ GTAVGT+ Sbjct 120 RQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYN 179 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ DEVTYRADIYALACVL ECLTGAPPYRADS L+++HLM P PQPS +RP Sbjct 180 YMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRP 239 Query 241 G-IPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 G +P A D V+A+GMAK P +R+ SAGDLA+AAH+AL+ +Q A ILRR +TL A Sbjct 240 GRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLAT 299 Query 300 PKPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWA 358 P + A A PP TP + +P S T A P A R G +W Sbjct 300 PADTGLSQSESGIAGAGTGPP----TPGAARWSPGDSAT-VAGPLAADSRGG-----NWP 349 Query 359 PNSGPMPASGPTPTPQYYQGG-GWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVL 417 +G PA P Q G PP+G K W +V GAAA+VLV ++ Sbjct 350 SQTGHSPA-----VPNALQASLGHAVPPAG---------NKRKVWAVV-GAAAIVLVAIV 394 Query 418 GAIGIWIAIRPK 429 A G ++ +RP Sbjct 395 AAAG-YLVLRPS 405 >gi|254821942|ref|ZP_05226943.1| transmembrane serine/threonine-protein kinase E PknE [Mycobacterium intracellulare ATCC 13950] Length=326 Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 199/293 (68%), Positives = 245/293 (84%), Gaps = 1/293 (0%) Query 6 DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREA 65 D+R GS FGPY L+RL+GRGGMG+VYEAE TV+E VA+KLM+ S DPVFR RM+REA Sbjct 16 DTRAGSQFGPYLLRRLVGRGGMGDVYEAEDTVRERVVALKLMSPTLSNDPVFRSRMQREA 75 Query 66 RIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIAS 125 R AGRL EPHVVPIHD+GE+DGQ++++MRLV+G DL +LKR+GPL+PPRAVAI+ QI S Sbjct 76 RTAGRLHEPHVVPIHDFGEIDGQLYVDMRLVDGKDLAGMLKRYGPLSPPRAVAIVRQIGS 135 Query 126 ALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPE 185 ALDAAHA G++HRDVKP+NIL++ DDFAYLVDFGIASAT+DEKLTQ+GT VGT KYMAPE Sbjct 136 ALDAAHAAGILHRDVKPENILVSADDFAYLVDFGIASATSDEKLTQIGTTVGTAKYMAPE 195 Query 186 RFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKA 245 RF + +VT+RADIYALACVL+ECLTG+PPY D +++ +H+ PIP+PSA RP IP Sbjct 196 RFGDSQVTHRADIYALACVLYECLTGSPPYTGDQL-SVIGAHVHQPIPRPSAARPSIPAG 254 Query 246 FDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPA 298 FD V+ARGMAK P+DRY + GDL+ AA+ AL+ PDQD A DIL R+Q +T P+ Sbjct 255 FDEVIARGMAKNPDDRYLTCGDLSSAAYAALAAPDQDRATDILARTQMATPPS 307 >gi|289442346|ref|ZP_06432090.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis T46] gi|289415265|gb|EFD12505.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis T46] Length=664 Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 240/432 (56%), Positives = 294/432 (69%), Gaps = 30/432 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDA +VGS FGPY L RLLGRGGMGEVYEAE T K VA+KL++ ++S + VFR R Sbjct 1 MSDAV-PQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRAR 59 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REA AGRL EPH+VPIHDYGE++GQ F+EMR+++GT L ++LK++GPLTP RAVAI+ Sbjct 60 MQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIV 119 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QIA+ALDAAHA+GV HRDVKP+NIL+T DFAYLVDFGIA A +D LTQ GTAVGT+ Sbjct 120 RQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYN 179 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ DEVTYRADIYALACVL ECLTGAPPYRADS L+++HLM P PQPS +RP Sbjct 180 YMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRP 239 Query 241 G-IPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 G +P A D V+A+GMAK P +R+ SAGDLA+AAH+AL+ +Q A ILRR +TL A Sbjct 240 GRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLAT 299 Query 300 PKPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWA 358 P + A A PP TP + +P S T A P A R G +W Sbjct 300 PADTGLSQSESGIAGAGTGPP----TPGAARWSPGDSAT-VAGPLAADSRGG-----NWP 349 Query 359 PNSGPMPASGPTPTPQYYQGG-GWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVL 417 +G PA P Q G PP+G K W +V GAAA+VLV ++ Sbjct 350 SQTGHSPA-----VPNALQASLGHAVPPAG---------NKRKVWAVV-GAAAIVLVAIV 394 Query 418 GAIGIWIAIRPK 429 A G ++ +RP Sbjct 395 AAAG-YLVLRPS 405 >gi|339630994|ref|YP_004722636.1| Ser/Thr protein kinase D [Mycobacterium africanum GM041182] gi|339330350|emb|CCC26012.1| transmembrane serine/threonine-protein kinase D PKND (protein kinase D) [Mycobacterium africanum GM041182] Length=664 Score = 415 bits (1066), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 240/432 (56%), Positives = 294/432 (69%), Gaps = 30/432 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDA +VGS FGPY L RLLGRGGMGEVYEAE T K VA+KL++ ++S + VFR R Sbjct 1 MSDAV-PQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRAR 59 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REA AGRL EPH+VPIHDYGE++GQ F+EMR+++GT L ++LK++GPLTP RAVAI+ Sbjct 60 MQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIV 119 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QIA+ALDAAHA+GV HRDVKP+NIL+T DFAYLVDFGIA A +D LTQ GTAVGT+ Sbjct 120 RQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYN 179 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ DEVTYRADIYALACVL ECLTGAPPYRADS L+++HLM P PQPS +RP Sbjct 180 YMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMHPAPQPSQLRP 239 Query 241 G-IPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 G +P A D V+A+GMAK P +R+ SAGDLA+AAH+AL+ +Q A ILRR +TL A Sbjct 240 GRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLAT 299 Query 300 PKPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWA 358 P + A A PP TP + +P S T A P A R G +W Sbjct 300 PADTGLSQSESGIAGAGTGPP----TPGAARWSPGDSAT-VAGPLAADSRGG-----NWP 349 Query 359 PNSGPMPASGPTPTPQYYQGG-GWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVL 417 +G PA P Q G PP+G K W +V GAAA+VLV ++ Sbjct 350 SQTGHSPA-----VPNALQASLGHAVPPAG---------NKRKVWAVV-GAAAIVLVAIV 394 Query 418 GAIGIWIAIRPK 429 A G ++ +RP Sbjct 395 AAAG-YLVLRPS 405 >gi|306775061|ref|ZP_07413398.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis SUMu001] gi|308216410|gb|EFO75809.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis SUMu001] Length=659 Score = 413 bits (1062), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 240/432 (56%), Positives = 294/432 (69%), Gaps = 30/432 (6%) Query 1 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 MSDA +VGS FGPY L RLLGRGGMGEVYEAE T K VA+KL++ ++S + VFR R Sbjct 1 MSDAV-PQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRAR 59 Query 61 MKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAII 120 M+REA AGRL EPH+VPIHDYGE++GQ F+EMR+++GT L ++LK++GPLTP RAVAI+ Sbjct 60 MQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIV 119 Query 121 TQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWK 180 QIA+ALDAAHA+GV HRDVKP+NIL+T DFAYLVDFGIA A +D LTQ GTAVGT+ Sbjct 120 RQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYN 179 Query 181 YMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRP 240 YMAPERF+ DEVTYRADIYALACVL ECLTGAPPYRADS L+++HLM P PQPS +RP Sbjct 180 YMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRP 239 Query 241 G-IPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 G +P A D V+A+GMAK P +R+ SAGDLA+AAH+AL+ +Q A ILRR +TL A Sbjct 240 GRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLAT 299 Query 300 PKPVP-PPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWA 358 P + A A PP TP + +P S T A P A R G +W Sbjct 300 PADTGLSQSESGIAGAGTGPP----TPGAARWSPGDSAT-VAGPLAADSRGG-----NWP 349 Query 359 PNSGPMPASGPTPTPQYYQGG-GWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVL 417 +G PA P Q G PP+G K W +V GAAA+VLV ++ Sbjct 350 SQTGHSPA-----VPNALQASLGHAVPPAG---------NKRKVWAVV-GAAAIVLVAIV 394 Query 418 GAIGIWIAIRPK 429 A G ++ +RP Sbjct 395 AAAG-YLVLRPS 405 >gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] gi|183177872|gb|ACC42982.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] Length=698 Score = 410 bits (1053), Expect = 5e-112, Method: Compositional matrix adjust. Identities = 193/294 (66%), Positives = 234/294 (80%), Gaps = 1/294 (0%) Query 7 SRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREAR 66 SRVGS FGPY L RL+GRGGMGEVYEAE T K VA+KL++ ++S +P FR RM+REA Sbjct 8 SRVGSRFGPYELVRLIGRGGMGEVYEAEDTRKRRVVALKLISTQYSGNPTFRARMQREAD 67 Query 67 IAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASA 126 AGRL EPH+VPIHDYGE+D Q F+EMRL++G L ++L +FGPLTP RAVAI+ QIA+A Sbjct 68 TAGRLTEPHIVPIHDYGEIDDQFFVEMRLIDGVSLRAMLTQFGPLTPARAVAIVRQIAAA 127 Query 127 LDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPER 186 LDAAH++GV HRDVKP+NIL+ +DFAYLVDFGIA A D LTQ G AVGT+ YMAPER Sbjct 128 LDAAHSNGVTHRDVKPENILVADNDFAYLVDFGIARAAADPGLTQGGMAVGTYNYMAPER 187 Query 187 FSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPG-IPKA 245 F+ ++VTYRADIYALACVL ECLTGAPPYRADS L+++HLM P P+PS +RPG +P A Sbjct 188 FTGNDVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMEPPPRPSQLRPGRVPAA 247 Query 246 FDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAP 299 D V+A+GMAK P++RY SAGDLA+AAHEAL+ P+Q A ILR+ L P Sbjct 248 LDEVIAKGMAKNPDERYMSAGDLAIAAHEALTTPEQRQEATILRQGDNMALMTP 301 Lambda K H 0.315 0.132 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1438247500800 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40